|  Help  |  About  |  Contact Us

Search our database by keyword

- or -

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 301 to 400 out of 1011 for Sirt1

Category restricted to Publication (x)

<< First    < Previous  |  Next >    Last >>
0.075s

Categories

Category: Publication
« show all
Type Details Score
Publication
25563725 | J:220749
First Author: Gilbert RE
Year: 2015
Journal: Diabetologia
Title: SIRT1 activation ameliorates hyperglycaemia by inducing a torpor-like state in an obese mouse model of type 2 diabetes.
Volume: 58
Issue: 4
Pages: 819-27
•
•
•
•
•
Publication
21965330 | J:178460
First Author: Wang RH
Year: 2011
Journal: J Clin Invest
Title: Hepatic Sirt1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance.
Volume: 121
Issue: 11
Pages: 4477-90
•
•
•
•
•
Publication
23980167 | J:201052
First Author: Yamamoto M
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: SIRT1 regulates adaptive response of the growth hormone--insulin-like growth factor-I axis under fasting conditions in liver.
Volume: 110
Issue: 37
Pages: 14948-53
•
•
•
•
•
Publication
23604553 | J:198959
First Author: White AT
Year: 2013
Journal: Diabetologia
Title: Skeletal muscle-specific overexpression of SIRT1 does not enhance whole-body energy expenditure or insulin sensitivity in young mice.
Volume: 56
Issue: 7
Pages: 1629-37
•
•
•
•
•
Publication
24184811 | J:301895
First Author: Li Y
Year: 2014
Journal: Gastroenterology
Title: Hepatic SIRT1 attenuates hepatic steatosis and controls energy balance in mice by inducing fibroblast growth factor 21.
Volume: 146
Issue: 2
Pages: 539-49.e7
•
•
•
•
•
Publication
33009367 | J:309309
First Author: Wang YM
Year: 2020
Journal: Cell Death Dis
Title: SIRT1 deacetylates mitochondrial trifunctional enzyme α subunit to inhibit ubiquitylation and decrease insulin resistance.
Volume: 11
Issue: 10
Pages: 821
•
•
•
•
•
Publication
37200907 | J:343400
 
First Author: Wang P
Year: 2023
Journal: J Orthop Translat
Title: Sirt1 protects against intervertebral disc degeneration induced by 1,25-dihydroxyvitamin D insufficiency in mice by inhibiting the NF-κB inflammatory pathway.
Volume: 40
Pages: 13-26
•
•
•
•
•
Publication
22290433 | J:183692
First Author: Purushotham A
Year: 2012
Journal: Mol Cell Biol
Title: Hepatic deletion of SIRT1 decreases hepatocyte nuclear factor 1α/farnesoid X receptor signaling and induces formation of cholesterol gallstones in mice.
Volume: 32
Issue: 7
Pages: 1226-36
•
•
•
•
•
Publication
34171408 | J:312530
 
First Author: Zhong G
Year: 2021
Journal: Neuroscience
Title: The Serum SIRT1 Protein is Associated with the Severity of Injury and Neurological Recovery in Mice with Traumatic Spinal Cord Injury.
Volume: 469
Pages: 103-109
•
•
•
•
•
Publication
26388263 | J:251331
 
First Author: Nadtochiy SM
Year: 2015
Journal: J Mol Cell Cardiol
Title: Metabolomic profiling of the heart during acute ischemic preconditioning reveals a role for SIRT1 in rapid cardioprotective metabolic adaptation.
Volume: 88
Pages: 64-72
•
•
•
•
•
Publication
30318050 | J:295285
 
First Author: Sun W
Year: 2018
Journal: Metabolism
Title: Overexpression of Sirt1 in mesenchymal stem cells protects against bone loss in mice by FOXO3a deacetylation and oxidative stress inhibition.
Volume: 88
Pages: 61-71
•
•
•
•
•
Publication
24425865 | J:209499
First Author: Sahar S
Year: 2014
Journal: J Biol Chem
Title: Circadian control of fatty acid elongation by SIRT1 protein-mediated deacetylation of acetyl-coenzyme A synthetase 1.
Volume: 289
Issue: 9
Pages: 6091-7
•
•
•
•
•
Publication
35342358 | J:322860
First Author: Li J
Year: 2022
Journal: Int J Biol Sci
Title: Specific overexpression of SIRT1 in mesenchymal stem cells rescues hematopoiesis niche in BMI1 knockout mice through promoting CXCL12 expression.
Volume: 18
Issue: 5
Pages: 2091-2103
•
•
•
•
•
Publication
21103071 | J:179193
First Author: Wang RH
Year: 2010
Journal: Int J Biol Sci
Title: Liver steatosis and increased ChREBP expression in mice carrying a liver specific SIRT1 null mutation under a normal feeding condition.
Volume: 6
Issue: 7
Pages: 682-90
•
•
•
•
•
Publication
31658614 | J:291009
 
First Author: Sanz MN
Year: 2019
Journal: Int J Mol Sci
Title: Inducible Cardiac-Specific Deletion of Sirt1 in Male Mice Reveals Progressive Cardiac Dysfunction and Sensitization of the Heart to Pressure Overload.
Volume: 20
Issue: 20
•
•
•
•
•
Publication
18230695 | J:135570
First Author: Nedachi T
Year: 2008
Journal: Am J Physiol Endocrinol Metab
Title: Ambient glucose levels qualify the potency of insulin myogenic actions by regulating SIRT1 and FoxO3a in C2C12 myocytes.
Volume: 294
Issue: 4
Pages: E668-78
•
•
•
•
•
Publication
22190494 | J:179993
First Author: Menssen A
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop.
Volume: 109
Issue: 4
Pages: E187-96
•
•
•
•
•
Publication
27339462 | J:246227
First Author: Li DJ
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: α7 Nicotinic Acetylcholine Receptor Relieves Angiotensin II-Induced Senescence in Vascular Smooth Muscle Cells by Raising Nicotinamide Adenine Dinucleotide-Dependent SIRT1 Activity.
Volume: 36
Issue: 8
Pages: 1566-76
•
•
•
•
•
Publication
28544355 | J:294692
First Author: Svensson K
Year: 2017
Journal: Acta Physiol (Oxf)
Title: Temporal overexpression of SIRT1 in skeletal muscle of adult mice does not improve insulin sensitivity or markers of mitochondrial biogenesis.
Volume: 221
Issue: 3
Pages: 193-203
•
•
•
•
•
Publication
26873964 | J:232936
First Author: Yamamoto T
Year: 2016
Journal: Am J Physiol Heart Circ Physiol
Title: Cardiac Sirt1 mediates the cardioprotective effect of caloric restriction by suppressing local complement system activation after ischemia-reperfusion.
Volume: 310
Issue: 8
Pages: H1003-14
•
•
•
•
•
Publication
20339025 | J:161763
First Author: Xu F
Year: 2010
Journal: Endocrinology
Title: Lack of SIRT1 (Mammalian Sirtuin 1) activity leads to liver steatosis in the SIRT1+/- mice: a role of lipid mobilization and inflammation.
Volume: 151
Issue: 6
Pages: 2504-14
•
•
•
•
•
Publication
24039251 | J:210197
First Author: Yao H
Year: 2013
Journal: Am J Physiol Lung Cell Mol Physiol
Title: SIRT1 redresses the imbalance of tissue inhibitor of matrix metalloproteinase-1 and matrix metalloproteinase-9 in the development of mouse emphysema and human COPD.
Volume: 305
Issue: 9
Pages: L615-24
•
•
•
•
•
Publication
20810901 | J:164001
First Author: Dietrich MO
Year: 2010
Journal: J Neurosci
Title: Agrp neurons mediate Sirt1's action on the melanocortin system and energy balance: roles for Sirt1 in neuronal firing and synaptic plasticity.
Volume: 30
Issue: 35
Pages: 11815-25
•
•
•
•
•
Publication
30705425 | J:329421
First Author: Lei Y
Year: 2020
Journal: Mol Psychiatry
Title: SIRT1 in forebrain excitatory neurons produces sexually dimorphic effects on depression-related behaviors and modulates neuronal excitability and synaptic transmission in the medial prefrontal cortex.
Volume: 25
Issue: 5
Pages: 1094-1111
•
•
•
•
•
Publication
23990359 | J:208926
First Author: Wang L
Year: 2013
Journal: Diabetes
Title: PPARα and Sirt1 mediate erythropoietin action in increasing metabolic activity and browning of white adipocytes to protect against obesity and metabolic disorders.
Volume: 62
Issue: 12
Pages: 4122-31
•
•
•
•
•
Publication
32003755 | J:304832
First Author: Cao K
Year: 2020
Journal: Aging (Albany NY)
Title: The neuroprotective effects of SIRT1 in mice carrying the APP/PS1 double-transgenic mutation and in SH-SY5Y cells over-expressing human APP670/671 may involve elevated levels of α7 nicotinic acetylcholine receptors.
Volume: 12
Issue: 2
Pages: 1792-1807
•
•
•
•
•
Publication
19934264 | J:182482
First Author: Kang MR
Year: 2010
Journal: Nucleic Acids Res
Title: Reciprocal roles of SIRT1 and SKIP in the regulation of RAR activity: implication in the retinoic acid-induced neuronal differentiation of P19 cells.
Volume: 38
Issue: 3
Pages: 822-31
•
•
•
•
•
Publication
31421827 | J:291839
First Author: Li W
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Inhibition of SIRT1 in hippocampal CA1 ameliorates PTSD-like behaviors in mice by protections of neuronal plasticity and serotonin homeostasis via NHLH2/MAO-A pathway.
Volume: 518
Issue: 2
Pages: 344-350
•
•
•
•
•
Publication
29162670 | J:271789
 
First Author: Liu Q
Year: 2017
Journal: Biosci Rep
Title: PU.1-deficient mice are resistant to thioacetamide-induced hepatic fibrosis: PU.1 finely regulates Sirt1 expression via transcriptional promotion of miR-34a and miR-29c in hepatic stellate cells.
Volume: 37
Issue: 6
•
•
•
•
•
Publication
28193684 | J:239815
First Author: Chen H
Year: 2017
Journal: J Neurosci
Title: An Agonist of the Protective Factor SIRT1 Improves Functional Recovery and Promotes Neuronal Survival by Attenuating Inflammation after Spinal Cord Injury.
Volume: 37
Issue: 11
Pages: 2916-2930
•
•
•
•
•
Publication
19553684 | J:153447
First Author: Amat R
Year: 2009
Journal: J Biol Chem
Title: SIRT1 controls the transcription of the peroxisome proliferator-activated receptor-gamma Co-activator-1alpha (PGC-1alpha) gene in skeletal muscle through the PGC-1alpha autoregulatory loop and interaction with MyoD.
Volume: 284
Issue: 33
Pages: 21872-80
•
•
•
•
•
Publication
21454709 | J:172671
First Author: Kong S
Year: 2011
Journal: J Biol Chem
Title: The type III histone deacetylase Sirt1 protein suppresses p300-mediated histone H3 lysine 56 acetylation at Bclaf1 promoter to inhibit T cell activation.
Volume: 286
Issue: 19
Pages: 16967-75
•
•
•
•
•
Publication
34473715 | J:309381
First Author: Sadegh C
Year: 2021
Journal: PLoS One
Title: Synthetic modified Fezf2 mRNA (modRNA) with concurrent small molecule SIRT1 inhibition enhances refinement of cortical subcerebral/corticospinal neuron identity from mouse embryonic stem cells.
Volume: 16
Issue: 9
Pages: e0254113
•
•
•
•
•
Publication
31794263 | J:286271
First Author: Svensson K
Year: 2020
Journal: Am J Physiol Endocrinol Metab
Title: Combined overexpression of SIRT1 and knockout of GCN5 in adult skeletal muscle does not affect glucose homeostasis or exercise performance in mice.
Volume: 318
Issue: 2
Pages: E145-E151
•
•
•
•
•
Publication
36568088 | J:332702
 
First Author: Artsi H
Year: 2022
Journal: Front Endocrinol (Lausanne)
Title: SIRT1 haplo-insufficiency results in reduced cortical bone thickness, increased porosity and decreased estrogen receptor alpha in bone in adult 129/Sv female mice.
Volume: 13
Pages: 1032262
•
•
•
•
•
Publication
25182532 | J:224330
First Author: Fu T
Year: 2014
Journal: Mol Cell Biol
Title: MicroRNA 34a inhibits beige and brown fat formation in obesity in part by suppressing adipocyte fibroblast growth factor 21 signaling and SIRT1 function.
Volume: 34
Issue: 22
Pages: 4130-42
•
•
•
•
•
Publication
31296102 | J:294570
First Author: Li F
Year: 2019
Journal: Cell Cycle
Title: Adipose-specific knockdown of Sirt1 results in obesity and insulin resistance by promoting exosomes release.
Volume: 18
Issue: 17
Pages: 2067-2082
•
•
•
•
•
Publication
36656684 | J:353985
First Author: Jiang H
Year: 2023
Journal: COPD
Title: FOXO3 Activation Prevents Cellular Senescence in Emphysema Induced by Cigarette Smoke.
Volume: 20
Issue: 1
Pages: 80-91
•
•
•
•
•
Publication
20167603 | J:165940
First Author: Guo X
Year: 2010
Journal: J Biol Chem
Title: DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1.
Volume: 285
Issue: 17
Pages: 13223-32
•
•
•
•
•
Publication
36322781 | J:338949
First Author: Lancho O
Year: 2023
Journal: Blood Cancer Discov
Title: A Therapeutically Targetable NOTCH1-SIRT1-KAT7 Axis in T-cell Leukemia.
Volume: 4
Issue: 1
Pages: 12-33
•
•
•
•
•
Publication
22033337 | J:316697
First Author: Muñoz-Fontela C
Year: 2011
Journal: Cell Cycle
Title: Acetylation is indispensable for p53 antiviral activity.
Volume: 10
Issue: 21
Pages: 3701-5
•
•
•
•
•
Publication
21102633 | J:166994
First Author: Herranz D
Year: 2010
Journal: Nat Rev Cancer
Title: SIRT1: recent lessons from mouse models.
Volume: 10
Issue: 12
Pages: 819-23
•
•
•
•
•
Publication
24073240 | J:207527
First Author: Zou T
Year: 2013
Journal: PLoS One
Title: Resveratrol Inhibits CD4+ T cell activation by enhancing the expression and activity of Sirt1.
Volume: 8
Issue: 9
Pages: e75139
•
•
•
•
•
Publication
22729177 | J:191603
First Author: Dietrich MO
Year: 2012
Journal: Nat Neurosci
Title: AgRP neurons regulate development of dopamine neuronal plasticity and nonfood-associated behaviors.
Volume: 15
Issue: 8
Pages: 1108-10
•
•
•
•
•
Publication
30193097 | J:265944
First Author: Latorre-Muro P
Year: 2018
Journal: Mol Cell
Title: Dynamic Acetylation of Phosphoenolpyruvate Carboxykinase Toggles Enzyme Activity between Gluconeogenic and Anaplerotic Reactions.
Volume: 71
Issue: 5
Pages: 718-732.e9
•
•
•
•
•
Publication
16098828 | J:100638
First Author: Moynihan KA
Year: 2005
Journal: Cell Metab
Title: Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice.
Volume: 2
Issue: 2
Pages: 105-17
•
•
•
•
•
Publication
18687325 | J:160869
First Author: Sequeira J
Year: 2008
Journal: Exp Cell Res
Title: sirt1-null mice develop an autoimmune-like condition.
Volume: 314
Issue: 16
Pages: 3069-74
•
•
•
•
•
Publication
21189328 | J:169315
First Author: Powell MJ
Year: 2011
Journal: Cancer Res
Title: Disruption of a Sirt1-dependent autophagy checkpoint in the prostate results in prostatic intraepithelial neoplasia lesion formation.
Volume: 71
Issue: 3
Pages: 964-75
•
•
•
•
•
Publication
31901447 | J:286191
First Author: Najt CP
Year: 2020
Journal: Mol Cell
Title: Lipid Droplet-Derived Monounsaturated Fatty Acids Traffic via PLIN5 to Allosterically Activate SIRT1.
Volume: 77
Issue: 4
Pages: 810-824.e8
•
•
•
•
•
Publication
24931715 | J:220725
First Author: Mercken EM
Year: 2014
Journal: Aging Cell
Title: SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass.
Volume: 13
Issue: 5
Pages: 787-96
•
•
•
•
•
Publication
20869593 | J:167861
First Author: Min SW
Year: 2010
Journal: Neuron
Title: Acetylation of tau inhibits its degradation and contributes to tauopathy.
Volume: 67
Issue: 6
Pages: 953-66
•
•
•
•
•
Publication
34631698 | J:312505
 
First Author: Chen B
Year: 2021
Journal: Front Cell Dev Biol
Title: A KDM4-DBC1-SIRT1 Axis Contributes to TGF-b Induced Mesenchymal Transition of Intestinal Epithelial Cells.
Volume: 9
Pages: 697614
•
•
•
•
•
Publication
22027215 | J:180689
First Author: Gomes AP
Year: 2012
Journal: Biochim Biophys Acta
Title: Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis.
Volume: 1822
Issue: 2
Pages: 185-95
•
•
•
•
•
Publication
23530205 | J:196193
First Author: Matarese G
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Hunger-promoting hypothalamic neurons modulate effector and regulatory T-cell responses.
Volume: 110
Issue: 15
Pages: 6193-8
•
•
•
•
•
Publication
27586459 | J:242106
 
First Author: Vikram A
Year: 2016
Journal: Nat Commun
Title: Vascular microRNA-204 is remotely governed by the microbiome and impairs endothelium-dependent vasorelaxation by downregulating Sirtuin1.
Volume: 7
Pages: 12565
•
•
•
•
•
Publication
25738568 | J:247295
First Author: Moreira D
Year: 2015
Journal: PLoS Pathog
Title: Leishmania infantum modulates host macrophage mitochondrial metabolism by hijacking the SIRT1-AMPK axis.
Volume: 11
Issue: 3
Pages: e1004684
•
•
•
•
•
Publication
24877878 | J:317514
First Author: Giblin W
Year: 2014
Journal: Trends Genet
Title: Sirtuins: guardians of mammalian healthspan.
Volume: 30
Issue: 7
Pages: 271-86
•
•
•
•
•
Publication
28923965 | J:256921
First Author: Fang J
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Sirt7 promotes adipogenesis in the mouse by inhibiting autocatalytic activation of Sirt1.
Volume: 114
Issue: 40
Pages: E8352-E8361
•
•
•
•
•
Publication
20816089 | J:166368
First Author: Kim HS
Year: 2010
Journal: Cell Metab
Title: Hepatic-specific disruption of SIRT6 in mice results in fatty liver formation due to enhanced glycolysis and triglyceride synthesis.
Volume: 12
Issue: 3
Pages: 224-36
•
•
•
•
•
Publication
25083875 | J:214604
First Author: Masri S
Year: 2014
Journal: Cell
Title: Partitioning circadian transcription by SIRT6 leads to segregated control of cellular metabolism.
Volume: 158
Issue: 3
Pages: 659-72
•
•
•
•
•
Publication
24214980 | J:207189
First Author: Yang H
Year: 2013
Journal: J Biol Chem
Title: Histone deacetylase sirtuin 1 deacetylates IRF1 protein and programs dendritic cells to control Th17 protein differentiation during autoimmune inflammation.
Volume: 288
Issue: 52
Pages: 37256-66
•
•
•
•
•
Publication
29634925 | J:270335
First Author: Kim KE
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Myeloid sirtuin1 deficiency aggravates hippocampal inflammation in mice fed high-fat diets.
Volume: 499
Issue: 4
Pages: 1025-1031
•
•
•
•
•
Publication
25155613 | J:215562
First Author: Tang S
Year: 2014
Journal: Mol Cell
Title: SIRT1-mediated deacetylation of CRABPII regulates cellular retinoic acid signaling and modulates embryonic stem cell differentiation.
Volume: 55
Issue: 6
Pages: 843-855
•
•
•
•
•
Publication
36194488 | J:334288
 
First Author: Luo N
Year: 2022
Journal: J Clin Invest
Title: A neuronal action of sirtuin 1 suppresses bone mass in young and aging mice.
Volume: 132
Issue: 23
•
•
•
•
•
Publication
25319116 | J:225706
 
First Author: Zhang SM
Year: 2014
Journal: Nat Commun
Title: Interferon regulatory factor 9 is critical for neointima formation following vascular injury.
Volume: 5
Pages: 5160
•
•
•
•
•
Publication
20493163 | J:164265
First Author: Hwang JW
Year: 2010
Journal: Arch Biochem Biophys
Title: Cigarette smoke-induced autophagy is regulated by SIRT1-PARP-1-dependent mechanism: implication in pathogenesis of COPD.
Volume: 500
Issue: 2
Pages: 203-9
•
•
•
•
•
Publication
25545407 | J:223236
First Author: Di Sante G
Year: 2015
Journal: Mol Endocrinol
Title: Sirt1-deficient mice have hypogonadotropic hypogonadism due to defective GnRH neuronal migration.
Volume: 29
Issue: 2
Pages: 200-12
•
•
•
•
•
Publication
28445726 | J:254520
First Author: Limagne E
Year: 2017
Journal: Cell Rep
Title: Sirtuin-1 Activation Controls Tumor Growth by Impeding Th17 Differentiation via STAT3 Deacetylation.
Volume: 19
Issue: 4
Pages: 746-759
•
•
•
•
•
Publication
22051242 | J:218881
First Author: Vinciguerra M
Year: 2012
Journal: Aging Cell
Title: mIGF-1/JNK1/SirT1 signaling confers protection against oxidative stress in the heart.
Volume: 11
Issue: 1
Pages: 139-49
•
•
•
•
•
Publication
31116983 | J:284382
First Author: Aras E
Year: 2019
Journal: Cell Rep
Title: Light Entrains Diurnal Changes in Insulin Sensitivity of Skeletal Muscle via Ventromedial Hypothalamic Neurons.
Volume: 27
Issue: 8
Pages: 2385-2398.e3
•
•
•
•
•
Publication
32441762 | J:302283
 
First Author: Dasgupta A
Year: 2020
Journal: J Exp Med
Title: SIRT1-NOX4 signaling axis regulates cancer cachexia.
Volume: 217
Issue: 7
•
•
•
•
•
Publication
27732856 | J:323551
First Author: Williams EO
Year: 2016
Journal: Cell Rep
Title: Sirtuin 1 Promotes Deacetylation of Oct4 and Maintenance of Naive Pluripotency.
Volume: 17
Issue: 3
Pages: 809-820
•
•
•
•
•
Publication
25454945 | J:219511
First Author: Liu T
Year: 2014
Journal: Mol Cell
Title: A divergent role of the SIRT1-TopBP1 axis in regulating metabolic checkpoint and DNA damage checkpoint.
Volume: 56
Issue: 5
Pages: 681-95
•
•
•
•
•
Publication
19578370 | J:150958
First Author: Zhou Y
Year: 2009
Journal: Nat Cell Biol
Title: Reversible acetylation of the chromatin remodelling complex NoRC is required for non-coding RNA-dependent silencing.
Volume: 11
Issue: 8
Pages: 1010-6
•
•
•
•
•
Publication
19286518 | J:147996
First Author: Nakahata Y
Year: 2009
Journal: Science
Title: Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1.
Volume: 324
Issue: 5927
Pages: 654-7
•
•
•
•
•
Publication
22055503 | J:179686
First Author: Oka S
Year: 2011
Journal: Cell Metab
Title: PPARα-Sirt1 complex mediates cardiac hypertrophy and failure through suppression of the ERR transcriptional pathway.
Volume: 14
Issue: 5
Pages: 598-611
•
•
•
•
•
Publication
30471862 | J:291084
First Author: Kim KE
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Effects of myeloid sirtuin 1 deficiency on hypothalamic neurogranin in mice fed a high-fat diet.
Volume: 508
Issue: 1
Pages: 123-129
•
•
•
•
•
Publication
29570999 | J:261120
First Author: Das A
Year: 2018
Journal: Cell
Title: Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging.
Volume: 173
Issue: 1
Pages: 74-89.e20
•
•
•
•
•
Publication
25822341 | J:259020
First Author: Morató L
Year: 2015
Journal: Cell Death Differ
Title: Activation of sirtuin 1 as therapy for the peroxisomal disease adrenoleukodystrophy.
Volume: 22
Issue: 11
Pages: 1742-53
•
•
•
•
•
Publication
25921090 | J:269580
First Author: Yoon MJ
Year: 2015
Journal: Cell Metab
Title: SIRT1-Mediated eNAMPT Secretion from Adipose Tissue Regulates Hypothalamic NAD+ and Function in Mice.
Volume: 21
Issue: 5
Pages: 706-17
•
•
•
•
•
Publication
26184910 | J:258837
First Author: Biel TG
Year: 2016
Journal: Cell Death Differ
Title: Sirtuin 1 suppresses mitochondrial dysfunction of ischemic mouse livers in a mitofusin 2-dependent manner.
Volume: 23
Issue: 2
Pages: 279-90
•
•
•
•
•
Publication
24360282 | J:205482
First Author: Gomes AP
Year: 2013
Journal: Cell
Title: Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging.
Volume: 155
Issue: 7
Pages: 1624-38
•
•
•
•
•
Publication
28181559 | J:275161
 
First Author: Kassan M
Year: 2017
Journal: Sci Rep
Title: Sirtuin1 protects endothelial Caveolin-1 expression and preserves endothelial function via suppressing miR-204 and endoplasmic reticulum stress.
Volume: 7
Pages: 42265
•
•
•
•
•
Publication
23329826 | J:196710
First Author: Menzies KJ
Year: 2013
Journal: J Biol Chem
Title: Sirtuin 1-mediated effects of exercise and resveratrol on mitochondrial biogenesis.
Volume: 288
Issue: 10
Pages: 6968-79
•
•
•
•
•
Publication
27554864 | J:241451
 
First Author: Gallardo-Montejano VI
Year: 2016
Journal: Nat Commun
Title: Nuclear Perilipin 5 integrates lipid droplet lipolysis with PGC-1α/SIRT1-dependent transcriptional regulation of mitochondrial function.
Volume: 7
Pages: 12723
•
•
•
•
•
Publication
31881009 | J:297808
First Author: Li B
Year: 2019
Journal: Aging (Albany NY)
Title: Sirt1-inducible deacetylation of p21 promotes cardiomyocyte proliferation.
Volume: 11
Issue: 24
Pages: 12546-12567
•
•
•
•
•
Publication
12960381 | J:85542
First Author: Cheng HL
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice.
Volume: 100
Issue: 19
Pages: 10794-9
•
•
•
•
•
Publication
17197703 | J:120915
First Author: Tanno M
Year: 2007
Journal: J Biol Chem
Title: Nucleocytoplasmic shuttling of the NAD+-dependent histone deacetylase SIRT1.
Volume: 282
Issue: 9
Pages: 6823-32
•
•
•
•
•
Publication
21998399 | J:189452
First Author: Wu J
Year: 2011
Journal: Diabetes
Title: WldS enhances insulin transcription and secretion via a SIRT1-dependent pathway and improves glucose homeostasis.
Volume: 60
Issue: 12
Pages: 3197-207
•
•
•
•
•
Publication
24416337 | J:212204
First Author: Michan S
Year: 2014
Journal: PLoS One
Title: Sirtuin1 over-expression does not impact retinal vascular and neuronal degeneration in a mouse model of oxygen-induced retinopathy.
Volume: 9
Issue: 1
Pages: e85031
•
•
•
•
•
Publication
38051904 | J:357482
First Author: Li B
Year: 2024
Journal: Neural Regen Res
Title: Neural stem cell-derived exosomes promote mitochondrial biogenesis and restore abnormal protein distribution in a mouse model of Alzheimer's disease.
Volume: 19
Issue: 7
Pages: 1593-1601
•
•
•
•
•
Publication
29940007 | J:262913
First Author: Assali DR
Year: 2018
Journal: PLoS One
Title: Food anticipatory activity on a calorie-restricted diet is independent of Sirt1.
Volume: 13
Issue: 6
Pages: e0199586
•
•
•
•
•
Publication
21060073 | J:179477
First Author: Hsu CP
Year: 2010
Journal: Circulation
Title: Silent information regulator 1 protects the heart from ischemia/reperfusion.
Volume: 122
Issue: 21
Pages: 2170-82
•
•
•
•
•
Publication
28993270 | J:321033
 
First Author: Han D
Year: 2017
Journal: Free Radic Biol Med
Title: Reduced silent information regulator 1 signaling exacerbates sepsis-induced myocardial injury and mitigates the protective effect of a liver X receptor agonist.
Volume: 113
Pages: 291-303
•
•
•
•
•
Publication
28191886 | J:251095
First Author: Vikram A
Year: 2017
Journal: Nat Med
Title: Sirtuin 1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel.
Volume: 23
Issue: 3
Pages: 361-367
•
•
•
•
•
Publication
37928261 | J:342370
First Author: Li H
Year: 2023
Journal: Int J Biol Sci
Title: Screening of an FDA-approved compound library identifies apigenin for the treatment of myocardial injury.
Volume: 19
Issue: 16
Pages: 5233-5244
•
•
•
•
•
Publication
25040736 | J:216808
First Author: Wan YZ
Year: 2014
Journal: Aging Cell
Title: SIRT1-mediated epigenetic downregulation of plasminogen activator inhibitor-1 prevents vascular endothelial replicative senescence.
Volume: 13
Issue: 5
Pages: 890-9
•
•
•
•
•
Publication
20008278 | J:158436
First Author: Sulaiman M
Year: 2010
Journal: Am J Physiol Heart Circ Physiol
Title: Resveratrol, an activator of SIRT1, upregulates sarcoplasmic calcium ATPase and improves cardiac function in diabetic cardiomyopathy.
Volume: 298
Issue: 3
Pages: H833-43
•
•
•
•
•
Publication
29050301 | J:298800
First Author: Peng J
Year: 2017
Journal: Oncotarget
Title: MiR-377 promotes white adipose tissue inflammation and decreases insulin sensitivity in obesity via suppression of sirtuin-1 (SIRT1).
Volume: 8
Issue: 41
Pages: 70550-70563
•
•
•
•
•
Publication
29405961 | J:262820
 
First Author: Arul Nambi Rajan K
Year: 2018
Journal: Placenta
Title: Sirtuin1 is required for proper trophoblast differentiation and placental development in mice.
Volume: 62
Pages: 1-8
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom