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Search results 301 to 400 out of 538 for Snca

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Category: Publication
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Type Details Score
Publication
29367610 | J:260213
First Author: Svarcbahs R
Year: 2018
Journal: Sci Rep
Title: Removal of prolyl oligopeptidase reduces alpha-synuclein toxicity in cells and in vivo.
Volume: 8
Issue: 1
Pages: 1552
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Publication
29166608 | J:254936
First Author: Oh CK
Year: 2017
Journal: Cell Rep
Title: S-Nitrosylation of PINK1 Attenuates PINK1/Parkin-Dependent Mitophagy in hiPSC-Based Parkinson's Disease Models.
Volume: 21
Issue: 8
Pages: 2171-2182
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Publication
23393156 | J:194306
First Author: Schultheis PJ
Year: 2013
Journal: Hum Mol Genet
Title: Atp13a2-deficient mice exhibit neuronal ceroid lipofuscinosis, limited α-synuclein accumulation and age-dependent sensorimotor deficits.
Volume: 22
Issue: 10
Pages: 2067-82
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Publication
25028513 | J:317643
First Author: Suzuki Y
Year: 2014
Journal: J Biol Chem
Title: β-III Tubulin fragments inhibit α-synuclein accumulation in models of multiple system atrophy.
Volume: 289
Issue: 35
Pages: 24374-82
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Publication
24076025 | J:202009
First Author: Roy A
Year: 2013
Journal: FEBS Lett
Title: Ankyrin repeat and BTB/POZ domain containing protein-2 inhibits the aggregation of alpha-synuclein: implications for Parkinson's disease.
Volume: 587
Issue: 21
Pages: 3567-74
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Publication
24983211 | J:215464
 
First Author: Yin G
Year: 2014
Journal: Neurobiol Dis
Title: α-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner.
Volume: 70
Pages: 149-61
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Publication
18702517 | J:140580
First Author: Sevlever D
Year: 2008
Journal: Biochemistry
Title: Cathepsin D is the main lysosomal enzyme involved in the degradation of alpha-synuclein and generation of its carboxy-terminally truncated species.
Volume: 47
Issue: 36
Pages: 9678-87
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Publication
19012742 | J:143080
First Author: Israeli E
Year: 2009
Journal: J Neurochem
Title: Beta-synuclein occurs in vivo in lipid-associated oligomers and forms hetero-oligomers with alpha-synuclein.
Volume: 108
Issue: 2
Pages: 465-74
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Publication
19885730 | J:159509
First Author: Zhong SC
Year: 2010
Journal: Cell Mol Neurobiol
Title: Expression and subcellular location of alpha-synuclein during mouse-embryonic development.
Volume: 30
Issue: 3
Pages: 469-82
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Publication
19553474 | J:164488
First Author: Sousa VL
Year: 2009
Journal: Mol Biol Cell
Title: {alpha}-synuclein and its A30P mutant affect actin cytoskeletal structure and dynamics.
Volume: 20
Issue: 16
Pages: 3725-39
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Publication
24866403 | J:218078
First Author: Du Y
Year: 2014
Journal: Neurobiol Aging
Title: Histone deacetylase 6 regulates cytotoxic α-synuclein accumulation through induction of the heat shock response.
Volume: 35
Issue: 10
Pages: 2316-28
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Publication
26663874 | J:248921
First Author: Chintalapudi SR
Year: 2016
Journal: FEBS J
Title: Multipronged approach to identify and validate a novel upstream regulator of Sncg in mouse retinal ganglion cells.
Volume: 283
Issue: 4
Pages: 678-93
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Publication
22508489 | J:315246
First Author: Spencer B
Year: 2013
Journal: Mol Ther
Title: Lentivirus mediated delivery of neurosin promotes clearance of wild-type α-synuclein and reduces the pathology in an α-synuclein model of LBD.
Volume: 21
Issue: 1
Pages: 31-41
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Publication
27881461 | J:329664
First Author: Sambri I
Year: 2017
Journal: EMBO Mol Med
Title: Lysosomal dysfunction disrupts presynaptic maintenance and restoration of presynaptic function prevents neurodegeneration in lysosomal storage diseases.
Volume: 9
Issue: 1
Pages: 112-132
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Publication
23013868 | J:324569
 
First Author: Sekigawa A
Year: 2012
Journal: Mol Brain
Title: Distinct mechanisms of axonal globule formation in mice expressing human wild type α-synuclein or dementia with Lewy bodies-linked P123H β-synuclein.
Volume: 5
Pages: 34
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Publication
9648883 | J:48620
First Author: Hsu LJ
Year: 1998
Journal: J Neurochem
Title: Expression pattern of synucleins (non-Abeta component of Alzheimer's disease amyloid precursor protein/alpha-synuclein) during murine brain development.
Volume: 71
Issue: 1
Pages: 338-44
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Publication
22371502 | J:184367
First Author: Joe MK
Year: 2012
Journal: J Biol Chem
Title: Myocilin interacts with syntrophins and is member of dystrophin-associated protein complex.
Volume: 287
Issue: 16
Pages: 13216-27
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Publication
9750188 | J:50153
First Author: Lavedan C
Year: 1998
Journal: Genome Res
Title: The synuclein family.
Volume: 8
Issue: 9
Pages: 871-80
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Publication
35172141 | J:324659
First Author: Sterling JK
Year: 2022
Journal: Cell Rep
Title: Interleukin-6 triggers toxic neuronal iron sequestration in response to pathological α-synuclein.
Volume: 38
Issue: 7
Pages: 110358
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Publication
16636270 | J:109461
First Author: Stanic AK
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Immune dysregulation accelerates atherosclerosis and modulates plaque composition in systemic lupus erythematosus.
Volume: 103
Issue: 18
Pages: 7018-23
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Publication
17018883 | J:129277
First Author: Ebadi M
Year: 2006
Journal: Exp Biol Med (Maywood)
Title: Metallothioneins 1 and 2 attenuate peroxynitrite-induced oxidative stress in Parkinson disease.
Volume: 231
Issue: 9
Pages: 1576-83
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Publication
19542206 | J:152425
First Author: Zuo P
Year: 2009
Journal: Toxicol Sci
Title: Potential role of alpha-synuclein and metallothionein in lead-induced inclusion body formation.
Volume: 111
Issue: 1
Pages: 100-8
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Publication
17227870 | J:119515
First Author: Ekstrand MI
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons.
Volume: 104
Issue: 4
Pages: 1325-30
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Publication
28855681 | J:256452
First Author: Aulić S
Year: 2017
Journal: Sci Rep
Title: α-Synuclein Amyloids Hijack Prion Protein to Gain Cell Entry, Facilitate Cell-to-Cell Spreading and Block Prion Replication.
Volume: 7
Issue: 1
Pages: 10050
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Publication
27733604 | J:236300
First Author: Ludtmann MH
Year: 2016
Journal: J Neurosci
Title: Monomeric Alpha-Synuclein Exerts a Physiological Role on Brain ATP Synthase.
Volume: 36
Issue: 41
Pages: 10510-10521
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Publication
27614017 | J:235050
 
First Author: Connor-Robson N
Year: 2016
Journal: Neurobiol Aging
Title: Combinational losses of synucleins reveal their differential requirements for compensating age-dependent alterations in motor behavior and dopamine metabolism.
Volume: 46
Pages: 107-12
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Publication
28993630 | J:323747
First Author: Baksi S
Year: 2017
Journal: Sci Rep
Title: α-Synuclein impairs ferritinophagy in the retinal pigment epithelium: Implications for retinal iron dyshomeostasis in Parkinson's disease.
Volume: 7
Issue: 1
Pages: 12843
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Publication
37542299 | J:341051
First Author: Chen X
Year: 2023
Journal: Mol Neurodegener
Title: VPS35 and α-Synuclein fail to interact to modulate neurodegeneration in rodent models of Parkinson's disease.
Volume: 18
Issue: 1
Pages: 51
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Publication
33273122 | J:300944
First Author: Somayaji M
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: A dual role for α-synuclein in facilitation and depression of dopamine release from substantia nigra neurons in vivo.
Volume: 117
Issue: 51
Pages: 32701-32710
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Publication
20356833 | J:164560
First Author: Lou H
Year: 2010
Journal: J Biol Chem
Title: Serine 129 phosphorylation reduces the ability of alpha-synuclein to regulate tyrosine hydroxylase and protein phosphatase 2A in vitro and in vivo.
Volume: 285
Issue: 23
Pages: 17648-61
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Publication
14585981 | J:86439
First Author: Ninkina N
Year: 2003
Journal: Mol Cell Biol
Title: Neurons expressing the highest levels of gamma-synuclein are unaffected by targeted inactivation of the gene.
Volume: 23
Issue: 22
Pages: 8233-45
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Publication
33091110 | J:308837
 
First Author: Bassil F
Year: 2021
Journal: J Exp Med
Title: α-Synuclein modulates tau spreading in mouse brains.
Volume: 218
Issue: 1
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Publication
15147505 | J:92213
First Author: Robertson DC
Year: 2004
Journal: J Neurochem
Title: Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of gamma-synuclein, alpha-synuclein and double alpha/gamma-synuclein null mutant mice.
Volume: 89
Issue: 5
Pages: 1126-36
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Publication
25917213 | J:309832
First Author: Lee SK
Year: 2015
Journal: Cerebellum
Title: α-Synuclein expression in the mouse cerebellum is restricted to VGluT1 excitatory terminals and is enriched in unipolar brush cells.
Volume: 14
Issue: 5
Pages: 516-27
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Publication
31899072 | J:291156
First Author: Henderson MX
Year: 2020
Journal: Neuron
Title: Glucocerebrosidase Activity Modulates Neuronal Susceptibility to Pathological α-Synuclein Insult.
Volume: 105
Issue: 5
Pages: 822-836.e7
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Publication
22355774 | J:207278
 
First Author: Shimshek DR
Year: 2012
Journal: Sci Rep
Title: Excess α-synuclein worsens disease in mice lacking ubiquitin carboxy-terminal hydrolase L1.
Volume: 2
Pages: 262
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Publication
26451483 | J:226090
First Author: Ejlerskov P
Year: 2015
Journal: Cell
Title: Lack of Neuronal IFN-β-IFNAR Causes Lewy Body- and Parkinson's Disease-like Dementia.
Volume: 163
Issue: 2
Pages: 324-39
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Publication
15465911 | J:93544
First Author: Chandra S
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions.
Volume: 101
Issue: 41
Pages: 14966-71
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Publication
27348587 | J:232550
First Author: Brahmachari S
Year: 2016
Journal: J Clin Invest
Title: Activation of tyrosine kinase c-Abl contributes to α-synuclein-induced neurodegeneration.
Volume: 126
Issue: 8
Pages: 2970-88
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Publication
28039592 | J:323046
First Author: Pavlin T
Year: 2017
Journal: Neurochem Res
Title: Loss or Mislocalization of Aquaporin-4 Affects Diffusion Properties and Intermediary Metabolism in Gray Matter of Mice.
Volume: 42
Issue: 1
Pages: 77-91
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Publication
20056137 | J:159729
First Author: Kurz A
Year: 2010
Journal: Neuroscience
Title: Alpha-synuclein deficiency affects brain Foxp1 expression and ultrasonic vocalization.
Volume: 166
Issue: 3
Pages: 785-95
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Publication
23209687 | J:195450
First Author: Schell H
Year: 2012
Journal: PLoS One
Title: Impaired c-Fos and polo-like kinase 2 induction in the limbic system of fear-conditioned α-synuclein transgenic mice.
Volume: 7
Issue: 11
Pages: e50245
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Publication
19680561 | J:244610
First Author: Fournier M
Year: 2009
Journal: PLoS One
Title: Parkin deficiency delays motor decline and disease manifestation in a mouse model of synucleinopathy.
Volume: 4
Issue: 8
Pages: e6629
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Publication
24619358 | J:210987
First Author: Diepenbroek M
Year: 2014
Journal: Hum Mol Genet
Title: Overexpression of the calpain-specific inhibitor calpastatin reduces human alpha-Synuclein processing, aggregation and synaptic impairment in [A30P]αSyn transgenic mice.
Volume: 23
Issue: 15
Pages: 3975-89
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Publication
26099047 | J:224864
First Author: Bachhuber T
Year: 2015
Journal: Nat Med
Title: Inhibition of amyloid-β plaque formation by α-synuclein.
Volume: 21
Issue: 7
Pages: 802-7
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Publication
34508096 | J:314207
First Author: Dutta D
Year: 2021
Journal: Nat Commun
Title: Selective targeting of the TLR2/MyD88/NF-κB pathway reduces α-synuclein spreading in vitro and in vivo.
Volume: 12
Issue: 1
Pages: 5382
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Publication
28288128 | J:244405
First Author: Logan T
Year: 2017
Journal: Nat Neurosci
Title: α-Synuclein promotes dilation of the exocytotic fusion pore.
Volume: 20
Issue: 5
Pages: 681-689
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Publication
20974939 | J:167549
First Author: Greten-Harrison B
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: αβγ-Synuclein triple knockout mice reveal age-dependent neuronal dysfunction.
Volume: 107
Issue: 45
Pages: 19573-8
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Publication
35417693 | J:325104
First Author: Carnazza KE
Year: 2022
Journal: Cell Rep
Title: Synaptic vesicle binding of α-synuclein is modulated by β- and γ-synucleins.
Volume: 39
Issue: 2
Pages: 110675
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Publication
37516240 | J:340456
First Author: Vargas KJ
Year: 2023
Journal: J Biol Chem
Title: α-Synuclein colocalizes with AP180 and affects the size of clathrin lattices.
Volume: 299
Issue: 9
Pages: 105091
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Publication
16597723 | J:107254
First Author: von Coelln R
Year: 2006
Journal: J Neurosci
Title: Inclusion body formation and neurodegeneration are parkin independent in a mouse model of alpha-synucleinopathy.
Volume: 26
Issue: 14
Pages: 3685-96
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Publication
23129765 | J:193755
First Author: Ninkina N
Year: 2012
Journal: J Biol Chem
Title: Contrasting effects of α-synuclein and γ-synuclein on the phenotype of cysteine string protein α (CSPα) null mutant mice suggest distinct function of these proteins in neuronal synapses.
Volume: 287
Issue: 53
Pages: 44471-7
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21846727 | J:177590
First Author: Emmer KL
Year: 2011
Journal: J Biol Chem
Title: E46K human alpha-synuclein transgenic mice develop Lewy-like and tau pathology associated with age-dependent, detrimental motor impairment.
Volume: 286
Issue: 40
Pages: 35104-18
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Publication
29547959 | J:261581
First Author: Papadopoulos VE
Year: 2018
Journal: Hum Mol Genet
Title: Modulation of β-glucocerebrosidase increases α-synuclein secretion and exosome release in mouse models of Parkinson's disease.
Volume: 27
Issue: 10
Pages: 1696-1710
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Publication
34321069 | J:328429
First Author: Ha TY
Year: 2021
Journal: Mol Brain
Title: Age-related increase in caveolin-1 expression facilitates cell-to-cell transmission of α-synuclein in neurons.
Volume: 14
Issue: 1
Pages: 122
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Publication
25009269 | J:215304
First Author: Vargas KJ
Year: 2014
Journal: J Neurosci
Title: Synucleins regulate the kinetics of synaptic vesicle endocytosis.
Volume: 34
Issue: 28
Pages: 9364-76
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11572944 | J:72239
First Author: Masliah E
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease.
Volume: 98
Issue: 21
Pages: 12245-50
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Publication
29272304 | J:254622
First Author: Zhou W
Year: 2017
Journal: PLoS One
Title: Running wheel exercise reduces α-synuclein aggregation and improves motor and cognitive function in a transgenic mouse model of Parkinson's disease.
Volume: 12
Issue: 12
Pages: e0190160
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26317866 | J:243017
First Author: Chen X
Year: 2015
Journal: PLoS One
Title: Longitudinal Metabolomics Profiling of Parkinson's Disease-Related α-Synuclein A53T Transgenic Mice.
Volume: 10
Issue: 8
Pages: e0136612
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20457918 | J:160542
First Author: Tong Y
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of alpha-synuclein, and apoptotic cell death in aged mice.
Volume: 107
Issue: 21
Pages: 9879-84
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Publication
30150626 | J:266239
First Author: Bae EJ
Year: 2018
Journal: Nat Commun
Title: LRRK2 kinase regulates α-synuclein propagation via RAB35 phosphorylation.
Volume: 9
Issue: 1
Pages: 3465
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Publication
24388731 | J:211953
First Author: Ginns EI
Year: 2014
Journal: Mol Genet Metab
Title: Neuroinflammation and α-synuclein accumulation in response to glucocerebrosidase deficiency are accompanied by synaptic dysfunction.
Volume: 111
Issue: 2
Pages: 152-62
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Publication
29246723 | J:268285
 
First Author: Schapansky J
Year: 2018
Journal: Neurobiol Dis
Title: Familial knockin mutation of LRRK2 causes lysosomal dysfunction and accumulation of endogenous insoluble α-synuclein in neurons.
Volume: 111
Pages: 26-35
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Publication
24412932 | J:210101
First Author: Mahul-Mellier AL
Year: 2014
Journal: Hum Mol Genet
Title: c-Abl phosphorylates α-synuclein and regulates its degradation: implication for α-synuclein clearance and contribution to the pathogenesis of Parkinson's disease.
Volume: 23
Issue: 11
Pages: 2858-79
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Publication
26643113 | J:338235
 
First Author: Helferich AM
Year: 2015
Journal: Mol Neurodegener
Title: α-synuclein interacts with SOD1 and promotes its oligomerization.
Volume: 10
Pages: 66
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Publication
22232689 | J:179915
First Author: Ranson A
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Homeostatic plasticity mechanisms are required for juvenile, but not adult, ocular dominance plasticity.
Volume: 109
Issue: 4
Pages: 1311-6
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21045828 | J:220941
 
First Author: Fujita M
Year: 2010
Journal: Nat Commun
Title: A β-synuclein mutation linked to dementia produces neurodegeneration when expressed in mouse brain.
Volume: 1
Pages: 110
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26170293 | J:225977
First Author: McGlinchey RP
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Cysteine cathepsins are essential in lysosomal degradation of α-synuclein.
Volume: 112
Issue: 30
Pages: 9322-7
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Publication
31041657 | J:295776
First Author: Bistaffa E
Year: 2019
Journal: Mol Neurobiol
Title: Prion Efficiently Replicates in α-Synuclein Knockout Mice.
Volume: 56
Issue: 11
Pages: 7448-7457
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Publication
33972291 | J:320992
 
First Author: Stoyka LE
Year: 2021
Journal: eNeuro
Title: Templated α-Synuclein Inclusion Formation Is Independent of Endogenous Tau.
Volume: 8
Issue: 3
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32560668 | J:319327
First Author: Takaichi Y
Year: 2020
Journal: Acta Neuropathol Commun
Title: Phosphorylation and oligomerization of α-synuclein associated with GSK-3β activation in the rTg4510 mouse model of tauopathy.
Volume: 8
Issue: 1
Pages: 86
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27378698 | J:237861
First Author: Magalhaes J
Year: 2016
Journal: Hum Mol Genet
Title: Autophagic lysosome reformation dysfunction in glucocerebrosidase deficient cells: relevance to Parkinson disease.
Volume: 25
Issue: 16
Pages: 3432-3445
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11312297 | J:68925
First Author: Simon HH
Year: 2001
Journal: J Neurosci
Title: Fate of midbrain dopaminergic neurons controlled by the engrailed genes.
Volume: 21
Issue: 9
Pages: 3126-34
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24691202 | J:215043
First Author: Cochain C
Year: 2014
Journal: PLoS One
Title: Programmed cell death-1 deficiency exacerbates T cell activation and atherogenesis despite expansion of regulatory T cells in atherosclerosis-prone mice.
Volume: 9
Issue: 4
Pages: e93280
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25825709 | J:220456
First Author: Wang S
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: α-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylation.
Volume: 112
Issue: 15
Pages: E1926-35
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29863470 | J:264191
   
First Author: Rousseaux MW
Year: 2018
Journal: Elife
Title: Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau.
Volume: 7
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21593311 | J:173360
First Author: Anwar S
Year: 2011
Journal: J Neurosci
Title: Functional alterations to the nigrostriatal system in mice lacking all three members of the synuclein family.
Volume: 31
Issue: 20
Pages: 7264-74
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23382946 | J:195914
First Author: Paine SM
Year: 2013
Journal: PLoS One
Title: Pale body-like inclusion formation and neurodegeneration following depletion of 26S proteasomes in mouse brain neurones are independent of α-synuclein.
Volume: 8
Issue: 1
Pages: e54711
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Publication
26676570 | J:329750
First Author: Fan Z
Year: 2016
Journal: Mol Neurobiol
Title: MicroRNA-7 Enhances Subventricular Zone Neurogenesis by Inhibiting NLRP3/Caspase-1 Axis in Adult Neural Stem Cells.
Volume: 53
Issue: 10
Pages: 7057-7069
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Publication
34736896 | J:346429
First Author: Ninkina N
Year: 2021
Journal: J Biol Chem
Title: β-synuclein potentiates synaptic vesicle dopamine uptake and rescues dopaminergic neurons from MPTP-induced death in the absence of other synucleins.
Volume: 297
Issue: 6
Pages: 101375
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Publication
27779468 | J:238738
   
First Author: Rousseaux MW
Year: 2016
Journal: Elife
Title: TRIM28 regulates the nuclear accumulation and toxicity of both alpha-synuclein and tau.
Volume: 5
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Publication
20858756 | J:172332
First Author: Geng X
Year: 2011
Journal: Am J Physiol Endocrinol Metab
Title: α-Synuclein binds the K(ATP) channel at insulin-secretory granules and inhibits insulin secretion.
Volume: 300
Issue: 2
Pages: E276-86
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Publication
25051958 | J:216227
First Author: Luo J
Year: 2014
Journal: Hum Mol Genet
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