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Search results 3101 to 3200 out of 5246 for App

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Category: Publication
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Type Details Score
Publication
10931940 | -
First Author: Farzan M
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: BACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein.
Volume: 97
Issue: 17
Pages: 9712-7
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Publication
10749877 | -
First Author: Bennett BD
Year: 2000
Journal: J Biol Chem
Title: Expression analysis of BACE2 in brain and peripheral tissues.
Volume: 275
Issue: 27
Pages: 20647-51
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Publication
38747498 | J:351617
First Author: Chen XQ
Year: 2024
Journal: Ann Neurol
Title: γ-Secretase Modulator BPN15606 Reduced Aβ42 and Aβ40 and Countered Alzheimer-Related Pathologies in a Mouse Model of Down Syndrome.
Volume: 96
Issue: 2
Pages: 390-404
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Publication
27023444 | J:253508
First Author: Belichenko PV
Year: 2016
Journal: PLoS One
Title: An Anti-β-Amyloid Vaccine for Treating Cognitive Deficits in a Mouse Model of Down Syndrome.
Volume: 11
Issue: 3
Pages: e0152471
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Publication
26341908 | J:227512
 
First Author: Overk CR
Year: 2015
Journal: Neuroscience
Title: Differential calcium alterations in animal models of neurodegenerative disease: Reversal by FK506.
Volume: 310
Pages: 549-60
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Publication
21383152 | J:170096
First Author: Park L
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid-beta.
Volume: 108
Issue: 12
Pages: 5063-8
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Publication
23382216 | J:194544
First Author: Park L
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Innate immunity receptor CD36 promotes cerebral amyloid angiopathy.
Volume: 110
Issue: 8
Pages: 3089-94
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Publication
34120899 | J:333785
First Author: Stoiljkovic M
Year: 2022
Journal: J Alzheimers Dis
Title: TREM2 Deficiency Disrupts Network Oscillations Leading to Epileptic Activity and Aggravates Amyloid-β-Related Hippocampal Pathophysiology in Mice.
Volume: 88
Issue: 3
Pages: 837-847
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Publication
22105352 | J:178937
First Author: Wen L
Year: 2011
Journal: J Cell Biol
Title: VPS35 haploinsufficiency increases Alzheimer's disease neuropathology.
Volume: 195
Issue: 5
Pages: 765-79
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Publication
28141794 | J:258573
First Author: You MH
Year: 2017
Journal: Cell Death Differ
Title: Death-associated protein kinase 1 phosphorylates NDRG2 and induces neuronal cell death.
Volume: 24
Issue: 2
Pages: 238-250
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Publication
36357367 | J:341736
First Author: Pan JX
Year: 2022
Journal: Cell Death Dis
Title: Muscular Swedish mutant APP-to-Brain axis in the development of Alzheimer's disease.
Volume: 13
Issue: 11
Pages: 952
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Publication
21115069 | J:174156
First Author: Blanchard J
Year: 2011
Journal: Behav Brain Res
Title: Detection of age-dependent working memory deterioration in APP751SL mice.
Volume: 218
Issue: 1
Pages: 129-37
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Publication
16519965 | J:121174
First Author: Sizova D
Year: 2007
Journal: Neurobiol Aging
Title: Proteomic analysis of brain tissue from an Alzheimer's disease mouse model by two-dimensional difference gel electrophoresis.
Volume: 28
Issue: 3
Pages: 357-70
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Publication
17350733 | J:140918
First Author: Blanchard J
Year: 2008
Journal: Neurobiol Aging
Title: Impairment of spatial memory consolidation in APP(751SL) mice results in cue-guided response.
Volume: 29
Issue: 7
Pages: 1011-21
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Publication
16337798 | J:108027
First Author: El Tannir El Tayara N
Year: 2006
Journal: Neurobiol Dis
Title: Age-related evolution of amyloid burden, iron load, and MR relaxation times in a transgenic mouse model of Alzheimer's disease.
Volume: 22
Issue: 1
Pages: 199-208
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Publication
17125750 | J:117687
First Author: Damjanac M
Year: 2007
Journal: Brain Res
Title: Fluoro-Jade B staining as useful tool to identify activated microglia and astrocytes in a mouse transgenic model of Alzheimer's disease.
Volume: 1128
Issue: 1
Pages: 40-9
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Publication
19428628 | J:148385
First Author: Blanchard J
Year: 2009
Journal: Behav Brain Res
Title: Characterization of cognition alteration across the course of the disease in APP751SL mice with parallel estimation of cerebral Abeta deposition.
Volume: 201
Issue: 1
Pages: 147-57
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Publication
17588710 | J:145822
First Author: Dhenain M
Year: 2009
Journal: Neurobiol Aging
Title: Characterization of in vivo MRI detectable thalamic amyloid plaques from APP/PS1 mice.
Volume: 30
Issue: 1
Pages: 41-53
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Publication
17566751 | J:134839
First Author: Cacquevel M
Year: 2007
Journal: Neurobiol Dis
Title: Ageing and amyloid-beta peptide deposition contribute to an impaired brain tissue plasminogen activator activity by different mechanisms.
Volume: 27
Issue: 2
Pages: 164-73
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Publication
28197095 | J:276720
 
First Author: Brendel M
Year: 2017
Journal: Front Aging Neurosci
Title: Increase of TREM2 during Aging of an Alzheimer's Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis.
Volume: 9
Pages: 8
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Publication
36906584 | J:339796
First Author: Ballweg A
Year: 2023
Journal: J Neuroinflammation
Title: [(18)F]F-DED PET imaging of reactive astrogliosis in neurodegenerative diseases: preclinical proof of concept and first-in-human data.
Volume: 20
Issue: 1
Pages: 68
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Publication
15922048 | J:98909
First Author: Woolley ML
Year: 2005
Journal: Behav Brain Res
Title: Age-related impairments in operant DMTP performance in the PS2APP mouse, a transgenic mouse model of Alzheimer's disease.
Volume: 161
Issue: 2
Pages: 220-8
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Publication
17008022 | J:116044
First Author: Güntert A
Year: 2006
Journal: Neuroscience
Title: High sensitivity analysis of amyloid-beta peptide composition in amyloid deposits from human and PS2APP mouse brain.
Volume: 143
Issue: 2
Pages: 461-75
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Publication
25456500 | J:223074
First Author: Šišková Z
Year: 2014
Journal: Neuron
Title: Dendritic structural degeneration is functionally linked to cellular hyperexcitability in a mouse model of Alzheimer's disease.
Volume: 84
Issue: 5
Pages: 1023-33
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Publication
17251422 | J:117779
First Author: Lopez-Lopez C
Year: 2007
Journal: J Neurosci
Title: Disturbed cross talk between insulin-like growth factor I and AMP-activated protein kinase as a possible cause of vascular dysfunction in the amyloid precursor protein/presenilin 2 mouse model of Alzheimer's disease.
Volume: 27
Issue: 4
Pages: 824-31
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Publication
11403971 | J:108749
First Author: Wirths O
Year: 2001
Journal: Neurosci Lett
Title: Intraneuronal Abeta accumulation precedes plaque formation in beta-amyloid precursor protein and presenilin-1 double-transgenic mice.
Volume: 306
Issue: 1-2
Pages: 116-20
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Publication
21531045 | J:188209
First Author: Petiet A
Year: 2012
Journal: Neurobiol Aging
Title: Gadolinium-staining reveals amyloid plaques in the brain of Alzheimer's transgenic mice.
Volume: 33
Issue: 8
Pages: 1533-44
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Publication
15207260 | J:91228
First Author: Delatour B
Year: 2004
Journal: Neurobiol Dis
Title: Alzheimer pathology disorganizes cortico-cortical circuitry: direct evidence from a transgenic animal model.
Volume: 16
Issue: 1
Pages: 41-7
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Publication
24927710 | J:284912
First Author: Trujillo-Estrada L
Year: 2014
Journal: J Alzheimers Dis
Title: Early neuronal loss and axonal/presynaptic damage is associated with accelerated amyloid-β accumulation in AβPP/PS1 Alzheimer's disease mice subiculum.
Volume: 42
Issue: 2
Pages: 521-41
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Publication
19661615 | J:274986
First Author: Moreno-Gonzalez I
Year: 2009
Journal: J Alzheimers Dis
Title: Extracellular amyloid-beta and cytotoxic glial activation induce significant entorhinal neuron loss in young PS1(M146L)/APP(751SL) mice.
Volume: 18
Issue: 4
Pages: 755-76
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Publication
30249297 | J:277619
First Author: Nguyen TV
Year: 2018
Journal: Acta Neuropathol Commun
Title: Alzheimer's associated amyloid and tau deposition co-localizes with a homeostatic myelin repair pathway in two mouse models of post-stroke mixed dementia.
Volume: 6
Issue: 1
Pages: 100
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21403389 | J:280595
First Author: Havas D
Year: 2011
Journal: J Alzheimers Dis
Title: A longitudinal study of behavioral deficits in an AβPP transgenic mouse model of Alzheimer's disease.
Volume: 25
Issue: 2
Pages: 231-43
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26620558 | J:276292
First Author: Spencer B
Year: 2016
Journal: J Biol Chem
Title: Systemic Central Nervous System (CNS)-targeted Delivery of Neuropeptide Y (NPY) Reduces Neurodegeneration and Increases Neural Precursor Cell Proliferation in a Mouse Model of Alzheimer Disease.
Volume: 291
Issue: 4
Pages: 1905-20
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35165441 | J:326161
First Author: Yang AC
Year: 2022
Journal: Nature
Title: A human brain vascular atlas reveals diverse mediators of Alzheimer's risk.
Volume: 603
Issue: 7903
Pages: 885-892
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Publication
17328871 | J:121462
 
First Author: Willis M
Year: 2007
Journal: Brain Res
Title: Localization and expression of substance P in transgenic mice overexpressing human APP751 with the London (V717I) and Swedish (K670M/N671L) mutations.
Volume: 1143
Pages: 199-207
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Publication
22574282 | J:281406
First Author: Faizi M
Year: 2012
Journal: Brain Behav
Title: Thy1-hAPP(Lond/Swe+) mouse model of Alzheimer's disease displays broad behavioral deficits in sensorimotor, cognitive and social function.
Volume: 2
Issue: 2
Pages: 142-54
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Publication
23643485 | J:211728
First Author: Löffler T
Year: 2013
Journal: Neurobiol Aging
Title: Impact of ApoB-100 expression on cognition and brain pathology in wild-type and hAPPsl mice.
Volume: 34
Issue: 10
Pages: 2379-88
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Publication
23555933 | J:200158
First Author: Lipsanen A
Year: 2013
Journal: PLoS One
Title: Non-selective calcium channel blocker bepridil decreases secondary pathology in mice after photothrombotic cortical lesion.
Volume: 8
Issue: 3
Pages: e60235
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Publication
25406061 | J:217691
First Author: Roth DM
Year: 2014
Journal: PLoS Biol
Title: Modulation of the maladaptive stress response to manage diseases of protein folding.
Volume: 12
Issue: 11
Pages: e1001998
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23545424 | J:211739
First Author: Knowles JK
Year: 2013
Journal: Neurobiol Aging
Title: Small molecule p75NTR ligand prevents cognitive deficits and neurite degeneration in an Alzheimer's mouse model.
Volume: 34
Issue: 8
Pages: 2052-63
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27836896 | J:239408
First Author: Merlini M
Year: 2017
Journal: Am J Physiol Heart Circ Physiol
Title: Reduced nitric oxide bioavailability mediates cerebroarterial dysfunction independent of cerebral amyloid angiopathy in a mouse model of Alzheimer's disease.
Volume: 312
Issue: 2
Pages: H232-H238
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Publication
30890928 | J:276312
 
First Author: Ni R
Year: 2019
Journal: Front Aging Neurosci
Title: fMRI Reveals Mitigation of Cerebrovascular Dysfunction by Bradykinin Receptors 1 and 2 Inhibitor Noscapine in a Mouse Model of Cerebral Amyloidosis.
Volume: 11
Pages: 27
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Publication
26834622 | J:244747
 
First Author: Ielacqua GD
Year: 2015
Journal: Front Aging Neurosci
Title: Magnetic Resonance Q Mapping Reveals a Decrease in Microvessel Density in the arcAβ Mouse Model of Cerebral Amyloidosis.
Volume: 7
Pages: 241
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Publication
23840405 | J:203724
First Author: Klohs J
Year: 2013
Journal: PLoS One
Title: Longitudinal Assessment of Amyloid Pathology in Transgenic ArcAβ Mice Using Multi-Parametric Magnetic Resonance Imaging.
Volume: 8
Issue: 6
Pages: e66097
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Publication
37298502 | J:348455
 
First Author: Choi Y
Year: 2023
Journal: Int J Mol Sci
Title: Capacitive Electrode-Based Electric Field Treatments on Redox-Toxic Iron Deposits in Transgenic AD Mouse Models: The Electroceutical Targeting of Alzheimer's Disease Feasibility Study.
Volume: 24
Issue: 11
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7592716 | J:29538
First Author: von Koch CS
Year: 1995
Journal: J Biol Chem
Title: The mouse APLP2 gene. Chromosomal localization and promoter characterization.
Volume: 270
Issue: 43
Pages: 25475-80
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36442651 | J:352444
 
First Author: Li YZ
Year: 2023
Journal: Neuropharmacology
Title: Reduced expression of APLP2 in spinal GABAergic inhibitory neurons contributed to nerve injury-induced microglial activation and pain sensitization.
Volume: 224
Pages: 109334
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Publication
27470171 | J:236530
First Author: Höfling C
Year: 2016
Journal: Aging Cell
Title: Differential transgene expression patterns in Alzheimer mouse models revealed by novel human amyloid precursor protein-specific antibodies.
Volume: 15
Issue: 5
Pages: 953-63
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19664757 | J:281363
First Author: España J
Year: 2010
Journal: Biol Psychiatry
Title: Intraneuronal beta-amyloid accumulation in the amygdala enhances fear and anxiety in Alzheimer's disease transgenic mice.
Volume: 67
Issue: 6
Pages: 513-21
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14645205 | J:87691
First Author: Jankowsky JL
Year: 2004
Journal: Hum Mol Genet
Title: Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase.
Volume: 13
Issue: 2
Pages: 159-70
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12486146 | J:129689
First Author: Buttini M
Year: 2002
Journal: J Neurosci
Title: Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation.
Volume: 22
Issue: 24
Pages: 10539-48
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23236499 | J:195677
First Author: Chen Y
Year: 2012
Journal: PLoS One
Title: Brain gene expression of a sporadic (icv-STZ Mouse) and a familial mouse model (3xTg-AD mouse) of Alzheimer's disease.
Volume: 7
Issue: 12
Pages: e51432
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36950017 | J:345220
 
First Author: Zhou X
Year: 2023
Journal: Front Pharmacol
Title: Evaluation of therapeutic effects of tetramethylpyrazine nitrone in Alzheimer's disease mouse model and proteomics analysis.
Volume: 14
Pages: 1082602
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36968493 | J:345227
 
First Author: Hu YT
Year: 2023
Journal: Front Neurosci
Title: Sex differences in hippocampal β-amyloid accumulation in the triple-transgenic mouse model of Alzheimer's disease and the potential role of local estrogens.
Volume: 17
Pages: 1117584
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26635562 | J:289580
 
First Author: Huang HJ
Year: 2015
Journal: Front Behav Neurosci
Title: Administration of NaHS Attenuates Footshock-Induced Pathologies and Emotional and Cognitive Dysfunction in Triple Transgenic Alzheimer's Mice.
Volume: 9
Pages: 312
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26582141 | J:290046
 
First Author: Hou X
Year: 2015
Journal: Front Aging Neurosci
Title: Differential contributions of ApoE4 and female sex to BACE1 activity and expression mediate Aβ deposition and learning and memory in mouse models of Alzheimer's disease.
Volume: 7
Pages: 207
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31062249 | J:348502
First Author: Ting LL
Year: 2019
Journal: Mol Neurobiol
Title: Expression of AHI1 Rescues Amyloidogenic Pathology in Alzheimer's Disease Model Cells.
Volume: 56
Issue: 11
Pages: 7572-7582
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18694898 | J:140396
First Author: Stokin GB
Year: 2008
Journal: Hum Mol Genet
Title: Amyloid precursor protein-induced axonopathies are independent of amyloid-beta peptides.
Volume: 17
Issue: 22
Pages: 3474-86
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27524794 | J:236982
First Author: Tiwari SS
Year: 2016
Journal: Brain
Title: Alzheimer-related decrease in CYFIP2 links amyloid production to tau hyperphosphorylation and memory loss.
Volume: 139
Issue: Pt 10
Pages: 2751-2765
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Publication
28647555 | J:260246
 
First Author: García-Cerro S
Year: 2017
Journal: Neurobiol Dis
Title: Normalizing the gene dosage of Dyrk1A in a mouse model of Down syndrome rescues several Alzheimer's disease phenotypes.
Volume: 106
Pages: 76-88
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31043483 | J:277174
First Author: Jiang Y
Year: 2019
Journal: J Neurosci
Title: Lysosomal Dysfunction in Down Syndrome Is APP-Dependent and Mediated by APP-βCTF (C99).
Volume: 39
Issue: 27
Pages: 5255-5268
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Publication
28337562 | J:336953
First Author: Alcarraz-Vizán G
Year: 2017
Journal: Cell Mol Life Sci
Title: BACE2 suppression promotes β-cell survival and function in a model of type 2 diabetes induced by human islet amyloid polypeptide overexpression.
Volume: 74
Issue: 15
Pages: 2827-2838
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34015524 | J:330292
 
First Author: Díaz-Catalán D
Year: 2021
Journal: Mol Metab
Title: BACE2 suppression in mice aggravates the adverse metabolic consequences of an obesogenic diet.
Volume: 53
Pages: 101251
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- | J:63102
   
First Author: Choi DK
Year: 2000
Journal: GenBank Submission
Title: Mus musculus aspartyl protease 1 mRNA, complete cds
Pages: AF216310
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28426964 | J:256027
First Author: Abud EM
Year: 2017
Journal: Neuron
Title: iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases.
Volume: 94
Issue: 2
Pages: 278-293.e9
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32999463 | J:297311
First Author: Badimon A
Year: 2020
Journal: Nature
Title: Negative feedback control of neuronal activity by microglia.
Volume: 586
Issue: 7829
Pages: 417-423
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32457076 | J:291055
First Author: Zhang H
Year: 2020
Journal: J Neurosci
Title: A Role of Low-Density Lipoprotein Receptor-Related Protein 4 (LRP4) in Astrocytic Aβ Clearance.
Volume: 40
Issue: 28
Pages: 5347-5361
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31375314 | J:283800
First Author: Hasselmann J
Year: 2019
Journal: Neuron
Title: Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo.
Volume: 103
Issue: 6
Pages: 1016-1033.e10
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Publication
33833046 | J:306099
 
First Author: Gulbranson DR
Year: 2021
Journal: eNeuro
Title: Phenotypic Differences between the Alzheimer's Disease-Related hAPP-J20 Model and Heterozygous Zbtb20 Knock-Out Mice.
Volume: 8
Issue: 3
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23605442 | J:200729
First Author: Crowe SE
Year: 2013
Journal: J Comp Neurol
Title: In vivo characterization of a bigenic fluorescent mouse model of Alzheimer's disease with neurodegeneration.
Volume: 521
Issue: 10
Pages: Spc1
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33097708 | J:296852
First Author: McQuade A
Year: 2020
Journal: Nat Commun
Title: Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease.
Volume: 11
Issue: 1
Pages: 5370
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39813317 | J:361219
First Author: Brandao W
Year: 2025
Journal: Sci Transl Med
Title: Inhaled xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy.
Volume: 17
Issue: 781
Pages: eadk3690
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Publication
33911285 | J:326194
First Author: Da Mesquita S
Year: 2021
Journal: Nature
Title: Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy.
Volume: 593
Issue: 7858
Pages: 255-260
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19041304 | J:174270
First Author: Levine S
Year: 2009
Journal: Exp Mol Pathol
Title: Systemic pathology in aged mouse models of Down's syndrome and Alzheimer's disease.
Volume: 86
Issue: 1
Pages: 18-22
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22926141 | J:188922
First Author: Manczak M
Year: 2012
Journal: Hum Mol Genet
Title: Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease.
Volume: 21
Issue: 23
Pages: 5131-46
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25947203 | J:351760
First Author: Plagg B
Year: 2015
Journal: Biogerontology
Title: Platelet dysfunction in hypercholesterolemia mice, two Alzheimer's disease mouse models and in human patients with Alzheimer's disease.
Volume: 16
Issue: 4
Pages: 543-58
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Publication
26159193 | J:264838
First Author: Plagg B
Year: 2015
Journal: Curr Alzheimer Res
Title: Increased Acetylation of Histone H4 at Lysine 12 (H4K12) in Monocytes of Transgenic Alzheimer's Mice and in Human Patients.
Volume: 12
Issue: 8
Pages: 752-60
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Publication
35883442 | J:345094
 
First Author: Xu G
Year: 2022
Journal: Biomolecules
Title: Modeling the Competition between Misfolded Aβ Conformers That Produce Distinct Types of Amyloid Pathology in Alzheimer's Disease.
Volume: 12
Issue: 7
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Publication
33766652 | J:307687
 
First Author: William CM
Year: 2021
Journal: Neurobiol Dis
Title: Impairment of visual cortical plasticity by amyloid-beta species.
Volume: 154
Pages: 105344
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16990547 | J:112842
First Author: Meyer-Luehmann M
Year: 2006
Journal: Science
Title: Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host.
Volume: 313
Issue: 5794
Pages: 1781-4
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Publication
18068129 | J:130326
First Author: Zhou XW
Year: 2008
Journal: FEBS Lett
Title: Parallel increase in p70 kinase activation and tau phosphorylation (S262) with Abeta overproduction.
Volume: 582
Issue: 2
Pages: 159-64
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7584867 | J:30392
First Author: Cho HS
Year: 1995
Journal: Comp Biochem Physiol B Biochem Mol Biol
Title: Age-related changes of mRNA expression of amyloid precursor protein in the brain of senescence-accelerated mouse.
Volume: 112
Issue: 2
Pages: 399-404
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7590737 | J:27752
First Author: Chrast R
Year: 1995
Journal: Genomics
Title: Mapping of the human transcription factor GABPA (E4TF1-60) gene to chromosome 21.
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