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Category: Publication
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Type Details Score
Publication
25436414 | J:216962
First Author: Yuyama K
Year: 2015
Journal: FEBS Lett
Title: A potential function for neuronal exosomes: sequestering intracerebral amyloid-β peptide.
Volume: 589
Issue: 1
Pages: 84-8
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Publication
37884349 | J:355536
First Author: Eckman EA
Year: 2023
Journal: J Neurosci
Title: Nascent Aβ42 Fibrillization in Synaptic Endosomes Precedes Plaque Formation in a Mouse Model of Alzheimer's-like β-Amyloidosis.
Volume: 43
Issue: 50
Pages: 8812-8824
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Publication
38326859 | J:350706
First Author: Daily KP
Year: 2024
Journal: Alzheimers Res Ther
Title: DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates inflammation and amyloid-β deposition in Alzheimer's disease.
Volume: 16
Issue: 1
Pages: 29
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Publication
19287391 | J:149374
First Author: Loane DJ
Year: 2009
Journal: Nat Med
Title: Amyloid precursor protein secretases as therapeutic targets for traumatic brain injury.
Volume: 15
Issue: 4
Pages: 377-9
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Publication
29298895 | J:262527
First Author: Hashimoto S
Year: 2018
Journal: J Biol Chem
Title: Endoplasmic reticulum stress responses in mouse models of Alzheimer's disease: Overexpression paradigm versus knockin paradigm.
Volume: 293
Issue: 9
Pages: 3118-3125
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Publication
28779511 | J:248482
First Author: Branca C
Year: 2017
Journal: Aging Cell
Title: Dyrk1 inhibition improves Alzheimer's disease-like pathology.
Volume: 16
Issue: 5
Pages: 1146-1154
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Publication
11848685 | J:75155
First Author: Niwa K
Year: 2002
Journal: Neurobiol Dis
Title: Alterations in cerebral blood flow and glucose utilization in mice overexpressing the amyloid precursor protein.
Volume: 9
Issue: 1
Pages: 61-8
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Publication
11796757 | J:73607
First Author: Zheng H
Year: 2002
Journal: J Neurochem
Title: Modulation of A(beta) peptides by estrogen in mouse models.
Volume: 80
Issue: 1
Pages: 191-6
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Publication
11290552 | J:68670
First Author: Matsuoka Y
Year: 2001
Journal: Am J Pathol
Title: Inflammatory responses to amyloidosis in a transgenic mouse model of Alzheimer's disease.
Volume: 158
Issue: 4
Pages: 1345-54
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Publication
24223856 | J:209324
First Author: Tajiri N
Year: 2013
Journal: PLoS One
Title: Traumatic brain injury precipitates cognitive impairment and extracellular Aβ aggregation in Alzheimer's disease transgenic mice.
Volume: 8
Issue: 11
Pages: e78851
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Publication
19674815 | J:173733
First Author: Vanmierlo T
Year: 2011
Journal: Neurobiol Aging
Title: Liver X receptor activation restores memory in aged AD mice without reducing amyloid.
Volume: 32
Issue: 7
Pages: 1262-72
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Publication
26379542 | J:271353
 
First Author: Biallosterski BT
Year: 2015
Journal: Front Aging Neurosci
Title: Changes in voiding behavior in a mouse model of Alzheimer's disease.
Volume: 7
Pages: 160
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Publication
28832675 | J:248072
First Author: Wang H
Year: 2017
Journal: PLoS One
Title: Time-course global proteome analyses reveal an inverse correlation between Aβ burden and immunoglobulin M levels in the APPNL-F mouse model of Alzheimer disease.
Volume: 12
Issue: 8
Pages: e0182844
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Publication
33971978 | J:311724
First Author: Ruiz-Riquelme A
Year: 2021
Journal: Acta Neuropathol Commun
Title: Aβ43 aggregates exhibit enhanced prion-like seeding activity in mice.
Volume: 9
Issue: 1
Pages: 83
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Publication
22518836 | J:186515
First Author: Boncompagni S
Year: 2012
Journal: J Biol Chem
Title: Mitochondrial dysfunction in skeletal muscle of amyloid precursor protein-overexpressing mice.
Volume: 287
Issue: 24
Pages: 20534-44
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Publication
34522221 | J:324397
First Author: Biechele G
Year: 2021
Journal: Theranostics
Title: Pre-therapeutic microglia activation and sex determine therapy effects of chronic immunomodulation.
Volume: 11
Issue: 18
Pages: 8964-8976
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Publication
- | J:303205
     
First Author: Magusali N
Year: 2021
Journal: bioRxiv
Title: Genetic variability associated with OAS1 expression in myeloid cells increases the risk of Alzheimer's disease and severe COVID-19 outcomes.
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Publication
10349858 | J:55025
First Author: Li QX
Year: 1999
Journal: J Neurochem
Title: Intracellular accumulation of detergent-soluble amyloidogenic A beta fragment of Alzheimer's disease precursor protein in the hippocampus of aged transgenic mice.
Volume: 72
Issue: 6
Pages: 2479-87
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Publication
10940226 | J:64575
First Author: Cherny RA
Year: 2000
Journal: J Struct Biol
Title: Chelation and intercalation: complementary properties in a compound for the treatment of Alzheimer's disease.
Volume: 130
Issue: 2-3
Pages: 209-16
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Publication
35243232 | J:324410
First Author: Kaneshiro N
Year: 2022
Journal: iScience
Title: Lipid flippase dysfunction as a therapeutic target for endosomal anomalies in Alzheimer's disease.
Volume: 25
Issue: 3
Pages: 103869
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Publication
19103644 | J:147312
First Author: Argellati F
Year: 2009
Journal: FASEB J
Title: Protein kinase C-dependent alpha-secretory processing of the amyloid precursor protein is mediated by phosphorylation of myosin II-B.
Volume: 23
Issue: 4
Pages: 1246-51
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Publication
10617132 | J:59022
First Author: Sheng JG
Year: 2000
Journal: J Neurochem
Title: Overexpression of the neuritotrophic cytokine S100beta precedes the appearance of neuritic beta-amyloid plaques in APPV717F mice.
Volume: 74
Issue: 1
Pages: 295-301
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Publication
19679659 | J:156978
First Author: Nishida Y
Year: 2009
Journal: J Biol Chem
Title: Depletion of vitamin E increases amyloid beta accumulation by decreasing its clearances from brain and blood in a mouse model of Alzheimer disease.
Volume: 284
Issue: 48
Pages: 33400-8
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Publication
20936700 | J:274035
First Author: Seino Y
Year: 2010
Journal: J Neurosci Res
Title: Amyloid β accelerates phosphorylation of tau and neurofibrillary tangle formation in an amyloid precursor protein and tau double-transgenic mouse model.
Volume: 88
Issue: 16
Pages: 3547-54
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Publication
28855626 | J:255802
First Author: Baglietto-Vargas D
Year: 2017
Journal: Sci Rep
Title: Dual roles of Aβ in proliferative processes in an amyloidogenic model of Alzheimer's disease.
Volume: 7
Issue: 1
Pages: 10085
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Publication
21323766 | J:176381
First Author: Chlan-Fourney J
Year: 2011
Journal: Eur J Neurosci
Title: The increased density of p38 mitogen-activated protein kinase-immunoreactive microglia in the sensorimotor cortex of aged TgCRND8 mice is associated predominantly with smaller dense-core amyloid plaques.
Volume: 33
Issue: 8
Pages: 1433-44
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Publication
24584353 | J:210257
 
First Author: Zhang W
Year: 2014
Journal: Nat Commun
Title: Amyloid precursor protein regulates neurogenesis by antagonizing miR-574-5p in the developing cerebral cortex.
Volume: 5
Pages: 3330
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Publication
22424792 | J:183235
 
First Author: Corrigan F
Year: 2012
Journal: Brain Res
Title: Characterisation of the effect of knockout of the amyloid precursor protein on outcome following mild traumatic brain injury.
Volume: 1451
Pages: 87-99
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Publication
17919826 | J:141485
First Author: Yang L
Year: 2007
Journal: Neuroscience
Title: Increased asynchronous release and aberrant calcium channel activation in amyloid precursor protein deficient neuromuscular synapses.
Volume: 149
Issue: 4
Pages: 768-78
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Publication
16822978 | J:144690
First Author: Priller C
Year: 2006
Journal: J Neurosci
Title: Synapse formation and function is modulated by the amyloid precursor protein.
Volume: 26
Issue: 27
Pages: 7212-21
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Publication
18955571 | J:201390
First Author: Qing H
Year: 2008
Journal: J Exp Med
Title: Valproic acid inhibits Abeta production, neuritic plaque formation, and behavioral deficits in Alzheimer's disease mouse models.
Volume: 205
Issue: 12
Pages: 2781-9
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Publication
11222652 | J:67583
First Author: Winkler DT
Year: 2001
Journal: J Neurosci
Title: Spontaneous hemorrhagic stroke in a mouse model of cerebral amyloid angiopathy.
Volume: 21
Issue: 5
Pages: 1619-27
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Publication
28287086 | J:244385
 
First Author: Klementieva O
Year: 2017
Journal: Nat Commun
Title: Pre-plaque conformational changes in Alzheimer's disease-linked Aβ and APP.
Volume: 8
Pages: 14726
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Publication
28753424 | J:252789
First Author: Szaruga M
Year: 2017
Journal: Cell
Title: Alzheimer's-Causing Mutations Shift Aβ Length by Destabilizing γ-Secretase-Aβn Interactions.
Volume: 170
Issue: 3
Pages: 443-456.e14
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Publication
33980545 | J:324392
First Author: Takamura R
Year: 2021
Journal: J Neurosci
Title: Modality-Specific Impairment of Hippocampal CA1 Neurons of Alzheimer's Disease Model Mice.
Volume: 41
Issue: 24
Pages: 5315-5329
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Publication
34831483 | J:324339
 
First Author: Liu X
Year: 2021
Journal: Cells
Title: Microglia-Based Sex-Biased Neuropathology in Early-Stage Alzheimer's Disease Model Mice and the Potential Pharmacologic Efficacy of Dioscin.
Volume: 10
Issue: 11
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Publication
16227582 | J:114737
First Author: Hashimoto Y
Year: 2005
Journal: Mol Cell Biol
Title: Transforming growth factor beta2 is a neuronal death-inducing ligand for amyloid-beta precursor protein.
Volume: 25
Issue: 21
Pages: 9304-17
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Publication
9951631 | J:52156
First Author: Hsiao K
Year: 1998
Journal: Exp Gerontol
Title: Transgenic mice expressing Alzheimer amyloid precursor proteins.
Volume: 33
Issue: 7-8
Pages: 883-9
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18936252 | J:140648
First Author: Sakurai T
Year: 2008
Journal: J Cell Biol
Title: Membrane microdomain switching: a regulatory mechanism of amyloid precursor protein processing.
Volume: 183
Issue: 2
Pages: 339-52
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Publication
19110058 | J:146364
First Author: Hébert SS
Year: 2009
Journal: Neurobiol Dis
Title: MicroRNA regulation of Alzheimer's Amyloid precursor protein expression.
Volume: 33
Issue: 3
Pages: 422-8
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Publication
20167227 | J:163208
First Author: Randall AD
Year: 2010
Journal: Neuropharmacology
Title: The functional neurophysiology of the amyloid precursor protein (APP) processing pathway.
Volume: 59
Issue: 4-5
Pages: 243-67
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Publication
25771168 | J:258954
 
First Author: Christianson MG
Year: 2015
Journal: Neurobiol Dis
Title: Differential roles of Aβ processing in hypoxia-induced axonal damage.
Volume: 77
Pages: 94-105
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Publication
31984308 | J:301133
First Author: An YA
Year: 2019
Journal: Nat Metab
Title: Dysregulation of Amyloid Precursor Protein Impairs Adipose Tissue Mitochondrial Function and Promotes Obesity.
Volume: 1
Issue: 12
Pages: 1243-1257
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Publication
9461064 | J:45851
First Author: von Koch CS
Year: 1997
Journal: Neurobiol Aging
Title: Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice.
Volume: 18
Issue: 6
Pages: 661-9
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Publication
22490781 | J:319557
First Author: Vella LJ
Year: 2012
Journal: FASEB J
Title: Identification of a novel amyloid precursor protein processing pathway that generates secreted N-terminal fragments.
Volume: 26
Issue: 7
Pages: 2930-40
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Publication
30506868 | J:273251
First Author: Truong PH
Year: 2019
Journal: Glia
Title: Amyloid precursor protein and amyloid precursor-like protein 2 have distinct roles in modulating myelination, demyelination, and remyelination of axons.
Volume: 67
Issue: 3
Pages: 525-538
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Publication
15919150 | J:100994
First Author: Yang G
Year: 2005
Journal: Neurosci Lett
Title: Reduced synaptic vesicle density and active zone size in mice lacking amyloid precursor protein (APP) and APP-like protein 2.
Volume: 384
Issue: 1-2
Pages: 66-71
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Publication
23585881 | J:200042
First Author: Zhang X
Year: 2013
Journal: PLoS One
Title: Hippocampal network oscillations in APP/APLP2-deficient mice.
Volume: 8
Issue: 4
Pages: e61198
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Publication
16584729 | J:111366
First Author: Siemes C
Year: 2006
Journal: Exp Cell Res
Title: Keratinocytes from APP/APLP2-deficient mice are impaired in proliferation, adhesion and migration in vitro.
Volume: 312
Issue: 11
Pages: 1939-49
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Publication
19625522 | J:151795
First Author: Peng S
Year: 2009
Journal: J Neurosci
Title: Decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of Alzheimer's disease.
Volume: 29
Issue: 29
Pages: 9321-9
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Publication
29311134 | J:261970
     
First Author: Kidana K
Year: 2018
Journal: EMBO Mol Med
Title: Loss of kallikrein-related peptidase 7 exacerbates amyloid pathology in Alzheimer's disease model mice.
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Publication
24760838 | J:210616
First Author: Parra-Damas A
Year: 2014
Journal: J Neurosci
Title: Crtc1 activates a transcriptional program deregulated at early Alzheimer's disease-related stages.
Volume: 34
Issue: 17
Pages: 5776-87
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Publication
29129695 | J:273422
First Author: Yin X
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Tetrahydroxystilbene glucoside modulates amyloid precursor protein processing via activation of AKT-GSK3β pathway in cells and in APP/PS1 transgenic mice.
Volume: 495
Issue: 1
Pages: 672-678
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Publication
17012232 | J:117621
First Author: Zerbinatti CV
Year: 2006
Journal: J Biol Chem
Title: Apolipoprotein E and low density lipoprotein receptor-related protein facilitate intraneuronal Abeta42 accumulation in amyloid model mice.
Volume: 281
Issue: 47
Pages: 36180-6
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Publication
24747018 | J:210621
 
First Author: Gu H
Year: 2014
Journal: Neuroscience
Title: The role of choroid plexus in IVIG-induced beta-amyloid clearance.
Volume: 270
Pages: 168-176
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Publication
16314516 | J:103763
First Author: Cao Q
Year: 2005
Journal: Mol Cell Biol
Title: Amyloid precursor proteins anchor CPEB to membranes and promote polyadenylation-induced translation.
Volume: 25
Issue: 24
Pages: 10930-9
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Publication
23719799 | J:198662
First Author: Megill A
Year: 2013
Journal: J Neurosci
Title: A tetra(ethylene glycol) derivative of benzothiazole aniline enhances Ras-mediated spinogenesis.
Volume: 33
Issue: 22
Pages: 9306-18
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Publication
30630900 | J:273342
 
First Author: Rice HC
Year: 2019
Journal: Science
Title: Secreted amyloid-β precursor protein functions as a GABABR1a ligand to modulate synaptic transmission.
Volume: 363
Issue: 6423
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Publication
33926999 | J:306668
First Author: Galanis C
Year: 2021
Journal: J Neurosci
Title: Amyloid-Beta Mediates Homeostatic Synaptic Plasticity.
Volume: 41
Issue: 24
Pages: 5157-5172
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Publication
25274811 | J:216597
First Author: Wang B
Year: 2014
Journal: J Neurosci
Title: The amyloid precursor protein controls adult hippocampal neurogenesis through GABAergic interneurons.
Volume: 34
Issue: 40
Pages: 13314-25
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Publication
29100987 | J:259322
 
First Author: Orr AG
Year: 2018
Journal: Neurobiol Dis
Title: Istradefylline reduces memory deficits in aging mice with amyloid pathology.
Volume: 110
Pages: 29-36
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Publication
31690660 | J:282370
First Author: Aikawa T
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: ABCA7 haplodeficiency disturbs microglial immune responses in the mouse brain.
Volume: 116
Issue: 47
Pages: 23790-23796
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Publication
35181976 | J:322941
First Author: Xie Z
Year: 2022
Journal: Aging Cell
Title: Microglial cathepsin E plays a role in neuroinflammation and amyloid β production in Alzheimer's disease.
Volume: 21
Issue: 3
Pages: e13565
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Publication
8207383 | J:18694
First Author: Salbaum JM
Year: 1994
Journal: J Exp Zool
Title: Embryonic expression pattern of amyloid protein precursor suggests a role in differentiation of specific subsets of neurons.
Volume: 269
Issue: 2
Pages: 116-27
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Publication
18497889 | J:137727
First Author: Pickford F
Year: 2008
Journal: J Clin Invest
Title: The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice.
Volume: 118
Issue: 6
Pages: 2190-9
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Publication
18393365 | J:134311
First Author: Needham BE
Year: 2008
Journal: J Pathol
Title: Identification of the Alzheimer's disease amyloid precursor protein (APP) and its homologue APLP2 as essential modulators of glucose and insulin homeostasis and growth.
Volume: 215
Issue: 2
Pages: 155-63
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Publication
22819135 | J:194432
First Author: Pimentel-Coelho PM
Year: 2013
Journal: Neurobiol Aging
Title: Effects of mild chronic cerebral hypoperfusion and early amyloid pathology on spatial learning and the cellular innate immune response in mice.
Volume: 34
Issue: 3
Pages: 679-93
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Publication
11053674 | J:65414
First Author: Dewachter I
Year: 2000
Journal: Exp Gerontol
Title: Modeling Alzheimer's disease in transgenic mice: effect of age and of presenilin1 on amyloid biochemistry and pathology in APP/London mice.
Volume: 35
Issue: 6-7
Pages: 831-41
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Publication
28499154 | J:241632
 
First Author: Xu F
Year: 2017
Journal: Thromb Res
Title: Mutation of the Kunitz-type proteinase inhibitor domain in the amyloid β-protein precursor abolishes its anti-thrombotic properties in vivo.
Volume: 155
Pages: 58-64
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Publication
15921918 | J:102542
First Author: Köhler C
Year: 2005
Journal: Neurobiol Dis
Title: Alzheimer's disease-like neuropathology of gene-targeted APP-SLxPS1mut mice expressing the amyloid precursor protein at endogenous levels.
Volume: 20
Issue: 2
Pages: 528-40
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Publication
23610434 | J:197345
First Author: Xie H
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Rapid cell death is preceded by amyloid plaque-mediated oxidative stress.
Volume: 110
Issue: 19
Pages: 7904-9
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Publication
22795785 | J:194433
First Author: Zhang X
Year: 2013
Journal: Neurobiol Aging
Title: Prenatal hypoxia may aggravate the cognitive impairment and Alzheimer's disease neuropathology in APPSwe/PS1A246E transgenic mice.
Volume: 34
Issue: 3
Pages: 663-78
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Publication
20532168 | J:161812
First Author: Netzer WJ
Year: 2010
Journal: PLoS One
Title: Lowering beta-amyloid levels rescues learning and memory in a Down syndrome mouse model.
Volume: 5
Issue: 6
Pages: e10943
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Publication
14985348 | J:89848
First Author: Davis J
Year: 2004
Journal: J Biol Chem
Title: Early-onset and robust cerebral microvascular accumulation of amyloid beta-protein in transgenic mice expressing low levels of a vasculotropic Dutch/Iowa mutant form of amyloid beta-protein precursor.
Volume: 279
Issue: 19
Pages: 20296-306
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Publication
15677459 | J:98747
First Author: Cappai R
Year: 2005
Journal: J Biol Chem
Title: The amyloid precursor protein (APP) of Alzheimer disease and its paralog, APLP2, modulate the Cu/Zn-Nitric Oxide-catalyzed degradation of glypican-1 heparan sulfate in vivo.
Volume: 280
Issue: 14
Pages: 13913-20
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Publication
21445342 | J:171673
First Author: Barbagallo AP
Year: 2011
Journal: PLoS One
Title: The intracellular threonine of amyloid precursor protein that is essential for docking of Pin1 is dispensable for developmental function.
Volume: 6
Issue: 3
Pages: e18006
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Publication
23815291 | J:202265
First Author: Laßek M
Year: 2013
Journal: J Neurochem
Title: Amyloid precursor proteins are constituents of the presynaptic active zone.
Volume: 127
Issue: 1
Pages: 48-56
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11050115 | J:65196
First Author: Heber S
Year: 2000
Journal: J Neurosci
Title: Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members.
Volume: 20
Issue: 21
Pages: 7951-63
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Publication
15561424 | J:95286
First Author: López-Sánchez N
Year: 2005
Journal: Neuroscience
Title: Lengthening of G2/mitosis in cortical precursors from mice lacking beta-amyloid precursor protein.
Volume: 130
Issue: 1
Pages: 51-60
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Publication
21873424 | J:177577
First Author: Kilger E
Year: 2011
Journal: J Biol Chem
Title: BRI2 protein regulates β-amyloid degradation by increasing levels of secreted insulin-degrading enzyme (IDE).
Volume: 286
Issue: 43
Pages: 37446-57
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Publication
25432317 | J:285095
First Author: Hick M
Year: 2015
Journal: Acta Neuropathol
Title: Acute function of secreted amyloid precursor protein fragment APPsα in synaptic plasticity.
Volume: 129
Issue: 1
Pages: 21-37
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Publication
34172567 | J:307211
 
First Author: Ludewig S
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: APPsα rescues impaired Ca2+ homeostasis in APP- and APLP2-deficient hippocampal neurons.
Volume: 118
Issue: 26
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Publication
22927427 | J:190030
First Author: Castellano JM
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Low-density lipoprotein receptor overexpression enhances the rate of brain-to-blood Aβ clearance in a mouse model of β-amyloidosis.
Volume: 109
Issue: 38
Pages: 15502-7
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Publication
28843453 | J:282606
 
First Author: Navarro G
Year: 2018
Journal: Brain Behav Immun
Title: Receptor-heteromer mediated regulation of endocannabinoid signaling in activated microglia. Role of CB1 and CB2 receptors and relevance for Alzheimer's disease and levodopa-induced dyskinesia.
Volume: 67
Pages: 139-151
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Publication
11896164 | J:75588
First Author: Jantzen PT
Year: 2002
Journal: J Neurosci
Title: Microglial activation and beta -amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice.
Volume: 22
Issue: 6
Pages: 2246-54
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