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Search results 401 to 500 out of 1236 for Cdkn2a

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Category: Publication
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Type Details Score
Publication
19056891 | J:142038
First Author: Signer RA
Year: 2008
Journal: Genes Dev
Title: Aging and cancer resistance in lymphoid progenitors are linked processes conferred by p16Ink4a and Arf.
Volume: 22
Issue: 22
Pages: 3115-20
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Publication
18809412 | J:168957
First Author: Sivakolundu SG
Year: 2008
Journal: J Mol Biol
Title: Intrinsically unstructured domains of Arf and Hdm2 form bimolecular oligomeric structures in vitro and in vivo.
Volume: 384
Issue: 1
Pages: 240-54
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Publication
22095712 | J:180377
First Author: Través PG
Year: 2011
Journal: J Immunol
Title: The tumor suppressor ARF regulates innate immune responses in mice.
Volume: 187
Issue: 12
Pages: 6527-38
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Publication
21233453 | J:184169
First Author: Cardenas JC
Year: 2011
Journal: Arterioscler Thromb Vasc Biol
Title: Overexpression of the cell cycle inhibitor p16INK4a promotes a prothrombotic phenotype following vascular injury in mice.
Volume: 31
Issue: 4
Pages: 827-33
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Publication
25485910 | J:227946
First Author: Yoda A
Year: 2015
Journal: Nat Med
Title: Mutations in G protein β subunits promote transformation and kinase inhibitor resistance.
Volume: 21
Issue: 1
Pages: 71-5
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Publication
24789920 | J:229850
First Author: Bantubungi K
Year: 2014
Journal: Diabetes
Title: Cdkn2a/p16Ink4a regulates fasting-induced hepatic gluconeogenesis through the PKA-CREB-PGC1α pathway.
Volume: 63
Issue: 10
Pages: 3199-209
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Publication
26950362 | J:234557
First Author: Helman A
Year: 2016
Journal: Nat Med
Title: p16(Ink4a)-induced senescence of pancreatic beta cells enhances insulin secretion.
Volume: 22
Issue: 4
Pages: 412-20
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Publication
26528722 | J:244391
First Author: Koudelkova P
Year: 2015
Journal: PLoS One
Title: Liver Sinusoidal Endothelial Cells Escape Senescence by Loss of p19ARF.
Volume: 10
Issue: 11
Pages: e0142134
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Publication
29216180 | J:252619
First Author: El-Athman R
Year: 2017
Journal: PLoS Biol
Title: The Ink4a/Arf locus operates as a regulator of the circadian clock modulating RAS activity.
Volume: 15
Issue: 12
Pages: e2002940
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Publication
32125276 | J:292431
   
First Author: Che H
Year: 2020
Journal: Elife
Title: p16 deficiency attenuates intervertebral disc degeneration by adjusting oxidative stress and nucleus pulposus cell cycle.
Volume: 9
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Publication
30790400 | J:295414
First Author: Kim SJ
Year: 2019
Journal: Aging Cell
Title: Endothelial toll-like receptor 4 maintains lung integrity via epigenetic suppression of p16INK4a.
Volume: 18
Issue: 3
Pages: e12914
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Publication
24522534 | J:315522
First Author: Sousa-Victor P
Year: 2014
Journal: Nature
Title: Geriatric muscle stem cells switch reversible quiescence into senescence.
Volume: 506
Issue: 7488
Pages: 316-21
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Publication
10753221 | J:61786
First Author: Meléndez B
Year: 2000
Journal: Carcinogenesis
Title: Characterization of the murine p19(ARF) promoter CpG island and its methylation pattern in primary lymphomas.
Volume: 21
Issue: 4
Pages: 817-21
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Publication
15567177 | J:94162
First Author: Suzuki H
Year: 2005
Journal: Biochem Biophys Res Commun
Title: The ARF tumor suppressor inhibits BCL6-mediated transcriptional repression.
Volume: 326
Issue: 1
Pages: 242-8
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Publication
17486078 | J:189986
First Author: Reef S
Year: 2007
Journal: Oncogene
Title: The autophagic inducer smARF interacts with and is stabilized by the mitochondrial p32 protein.
Volume: 26
Issue: 46
Pages: 6677-83
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Publication
9178896 | J:39206
First Author: Malumbres M
Year: 1997
Journal: Oncogene
Title: Inactivation of the cyclin-dependent kinase inhibitor p15INK4b by deletion and de novo methylation with independence of p16INK4a alterations in murine primary T-cell lymphomas.
Volume: 14
Issue: 11
Pages: 1361-70
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Publication
17043139 | J:114509
First Author: Wasmeier C
Year: 2006
Journal: J Cell Biol
Title: Rab38 and Rab32 control post-Golgi trafficking of melanogenic enzymes.
Volume: 175
Issue: 2
Pages: 271-81
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Publication
31428695 | J:288816
 
First Author: Cottage CT
Year: 2019
Journal: Commun Biol
Title: Targeting p16-induced senescence prevents cigarette smoke-induced emphysema by promoting IGF1/Akt1 signaling in mice.
Volume: 2
Pages: 307
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Publication
36125896 | J:337607
 
First Author: Haase S
Year: 2022
Journal: J Clin Invest
Title: H3.3-G34 mutations impair DNA repair and promote cGAS/STING-mediated immune responses in pediatric high-grade glioma models.
Volume: 132
Issue: 22
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Publication
19390085 | J:147943
First Author: Dhawan S
Year: 2009
Journal: Genes Dev
Title: Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation.
Volume: 23
Issue: 8
Pages: 906-11
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Publication
22351929 | J:182507
First Author: Oguro H
Year: 2012
Journal: J Exp Med
Title: Lethal myelofibrosis induced by Bmi1-deficient hematopoietic cells unveils a tumor suppressor function of the polycomb group genes.
Volume: 209
Issue: 3
Pages: 445-54
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Publication
23029524 | J:191959
First Author: Fan L
Year: 2012
Journal: PLoS One
Title: Bmi1 is required for hepatic progenitor cell expansion and liver tumor development.
Volume: 7
Issue: 9
Pages: e46472
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Publication
30895687 | J:291357
First Author: Chen G
Year: 2019
Journal: Stem Cells
Title: Bmi1 Overexpression in Mesenchymal Stem Cells Exerts Antiaging and Antiosteoporosis Effects by Inactivating p16/p19 Signaling and Inhibiting Oxidative Stress.
Volume: 37
Issue: 9
Pages: 1200-1211
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Publication
25832744 | J:224107
First Author: Yamakoshi K
Year: 2015
Journal: Aging Cell
Title: Dysregulation of the Bmi-1/p16(Ink⁴a) pathway provokes an aging-associated decline of submandibular gland function.
Volume: 14
Issue: 4
Pages: 616-24
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Publication
20207230 | J:158982
First Author: Oguro H
Year: 2010
Journal: Cell Stem Cell
Title: Poised lineage specification in multipotential hematopoietic stem and progenitor cells by the polycomb protein Bmi1.
Volume: 6
Issue: 3
Pages: 279-86
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16954369 | J:124627
First Author: Oguro H
Year: 2006
Journal: J Exp Med
Title: Differential impact of Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi1-deficient mice.
Volume: 203
Issue: 10
Pages: 2247-53
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Publication
9923679 | J:52056
First Author: Jacobs JJ
Year: 1999
Journal: Nature
Title: The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus.
Volume: 397
Issue: 6715
Pages: 164-8
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Publication
14574365 | J:89979
First Author: Molofsky AV
Year: 2003
Journal: Nature
Title: Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation.
Volume: 425
Issue: 6961
Pages: 962-7
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Publication
28790310 | J:275156
First Author: Jin J
Year: 2017
Journal: Sci Rep
Title: P16 INK4a Deletion Ameliorated Renal Tubulointerstitial Injury in a Stress-induced Premature Senescence Model of Bmi-1 Deficiency.
Volume: 7
Issue: 1
Pages: 7502
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Publication
24915841 | J:216517
First Author: Jin J
Year: 2014
Journal: Aging Cell
Title: Bmi-1 plays a critical role in protection from renal tubulointerstitial injury by maintaining redox balance.
Volume: 13
Issue: 5
Pages: 797-809
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Publication
31959867 | J:333099
First Author: Chen H
Year: 2020
Journal: Exp Mol Med
Title: TGF-β1/IL-11/MEK/ERK signaling mediates senescence-associated pulmonary fibrosis in a stress-induced premature senescence model of Bmi-1 deficiency.
Volume: 52
Issue: 1
Pages: 130-151
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Publication
18635350 | J:139803
First Author: Pietersen AM
Year: 2008
Journal: Curr Biol
Title: Bmi1 regulates stem cells and proliferation and differentiation of committed cells in mammary epithelium.
Volume: 18
Issue: 14
Pages: 1094-9
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11779495 | J:88792
First Author: Sharpless NE
Year: 2001
Journal: Mol Cell
Title: Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions.
Volume: 8
Issue: 6
Pages: 1187-96
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Publication
16510579 | J:106704
First Author: van Schanke A
Year: 2006
Journal: Cancer Res
Title: Induction of nevi and skin tumors in Ink4a/Arf Xpa knockout mice by neonatal, intermittent, or chronic UVB exposures.
Volume: 66
Issue: 5
Pages: 2608-15
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Publication
31563962 | J:309367
First Author: Fu Y
Year: 2020
Journal: Neuro Oncol
Title: TSPO deficiency induces mitochondrial dysfunction, leading to hypoxia, angiogenesis, and a growth-promoting metabolic shift toward glycolysis in glioblastoma.
Volume: 22
Issue: 2
Pages: 240-252
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Publication
17912041 | J:222385
First Author: Lee HJ
Year: 2007
Journal: Cell Cycle
Title: Loss of CABLES1, a cyclin-dependent kinase-interacting protein that inhibits cell cycle progression, results in germline expansion at the expense of oocyte quality in adult female mice.
Volume: 6
Issue: 21
Pages: 2678-84
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37106126 | J:337454
First Author: Guijarro MV
Year: 2023
Journal: Oncogene
Title: TYMS promotes genomic instability and tumor progression in Ink4a/Arf null background.
Volume: 42
Issue: 23
Pages: 1926-1939
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Publication
24338698 | J:209290
First Author: Catucci M
Year: 2014
Journal: Eur J Immunol
Title: Wiskott-Aldrich syndrome protein deficiency in natural killer and dendritic cells affects antitumor immunity.
Volume: 44
Issue: 4
Pages: 1039-45
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Publication
9353252 | J:44088
First Author: Chin L
Year: 1997
Journal: Genes Dev
Title: Cooperative effects of INK4a and ras in melanoma susceptibility in vivo.
Volume: 11
Issue: 21
Pages: 2822-34
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Publication
24056773 | J:202318
First Author: Pyonteck SM
Year: 2013
Journal: Nat Med
Title: CSF-1R inhibition alters macrophage polarization and blocks glioma progression.
Volume: 19
Issue: 10
Pages: 1264-72
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Publication
25543281 | J:232692
First Author: Rotty JD
Year: 2015
Journal: Dev Cell
Title: Profilin-1 serves as a gatekeeper for actin assembly by Arp2/3-dependent and -independent pathways.
Volume: 32
Issue: 1
Pages: 54-67
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Publication
24147027 | J:225181
First Author: Pong WW
Year: 2013
Journal: PLoS One
Title: F11R is a novel monocyte prognostic biomarker for malignant glioma.
Volume: 8
Issue: 10
Pages: e77571
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Publication
30456364 | J:286031
First Author: Giessner C
Year: 2018
Journal: Life Sci Alliance
Title: Vnn1 pantetheinase limits the Warburg effect and sarcoma growth by rescuing mitochondrial activity.
Volume: 1
Issue: 4
Pages: e201800073
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Publication
28759044 | J:247694
First Author: Yan D
Year: 2017
Journal: Oncogene
Title: Inhibition of colony stimulating factor-1 receptor abrogates microenvironment-mediated therapeutic resistance in gliomas.
Volume: 36
Issue: 43
Pages: 6049-6058
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Publication
38566120 | J:346860
First Author: Yalcin F
Year: 2024
Journal: Acta Neuropathol Commun
Title: Tumor associated microglia/macrophages utilize GPNMB to promote tumor growth and alter immune cell infiltration in glioma.
Volume: 12
Issue: 1
Pages: 50
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Publication
16620915 | J:110215
First Author: Cheong C
Year: 2006
Journal: Mech Ageing Dev
Title: Role of INK4a locus in normal eye development and cataract genesis.
Volume: 127
Issue: 7
Pages: 633-8
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Publication
19805150 | J:153678
First Author: Tamase A
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Identification of tumor-initiating cells in a highly aggressive brain tumor using promoter activity of nucleostemin.
Volume: 106
Issue: 40
Pages: 17163-8
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Publication
26884185 | J:231005
First Author: Lissanu Deribe Y
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Truncating PREX2 mutations activate its GEF activity and alter gene expression regulation in NRAS-mutant melanoma.
Volume: 113
Issue: 9
Pages: E1296-305
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17099725 | J:122886
First Author: Nilsson LM
Year: 2007
Journal: Oncogene
Title: Ink4c is dispensable for tumor suppression in Myc-induced B-cell lymphomagenesis.
Volume: 26
Issue: 20
Pages: 2833-9
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Publication
17510401 | J:121732
First Author: Ramsey MR
Year: 2007
Journal: Cancer Res
Title: Expression of p16Ink4a compensates for p18Ink4c loss in cyclin-dependent kinase 4/6-dependent tumors and tissues.
Volume: 67
Issue: 10
Pages: 4732-41
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Publication
21245485 | J:170512
First Author: Liu Y
Year: 2011
Journal: Blood
Title: Expression of p16(INK4a) prevents cancer and promotes aging in lymphocytes.
Volume: 117
Issue: 12
Pages: 3257-67
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10435599 | J:56600
First Author: Meléndez B
Year: 1999
Journal: Oncogene
Title: Loss of heterozygosity at the proximal-mid part of mouse chromosome 4 defines two novel tumor suppressor gene loci in T-cell lymphomas.
Volume: 18
Issue: 28
Pages: 4166-9
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Publication
22065720 | J:181044
First Author: Grange M
Year: 2012
Journal: Cancer Res
Title: Activated STAT5 promotes long-lived cytotoxic CD8+ T cells that induce regression of autochthonous melanoma.
Volume: 72
Issue: 1
Pages: 76-87
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Publication
37353538 | J:338133
First Author: Matsudaira T
Year: 2023
Journal: Commun Biol
Title: Cellular senescence in white matter microglia is induced during ageing in mice and exacerbates the neuroinflammatory phenotype.
Volume: 6
Issue: 1
Pages: 665
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Publication
24091330 | J:203979
First Author: Wang Y
Year: 2013
Journal: J Clin Invest
Title: p16(INK4a) protects against dysfunctional telomere-induced ATR-dependent DNA damage responses.
Volume: 123
Issue: 10
Pages: 4489-501
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Publication
25882552 | J:247262
First Author: Grange M
Year: 2015
Journal: Immunology
Title: Control of CD8 T cell proliferation and terminal differentiation by active STAT5 and CDKN2A/CDKN2B.
Volume: 145
Issue: 4
Pages: 543-57
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26139534 | J:225832
First Author: Giordano M
Year: 2015
Journal: EMBO J
Title: Molecular profiling of CD8 T cells in autochthonous melanoma identifies Maf as driver of exhaustion.
Volume: 34
Issue: 15
Pages: 2042-58
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Publication
25024217 | J:212245
First Author: Giordano M
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: The tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20) imposes a brake on antitumor activity of CD8 T cells.
Volume: 111
Issue: 30
Pages: 11115-20
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15894264 | J:98939
First Author: Nilsson JA
Year: 2005
Journal: Cancer Cell
Title: Targeting ornithine decarboxylase in Myc-induced lymphomagenesis prevents tumor formation.
Volume: 7
Issue: 5
Pages: 433-44
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35881544 | J:346271
   
First Author: Su W
Year: 2022
Journal: Elife
Title: Senescent preosteoclast secretome promotes metabolic syndrome associated osteoarthritis through cyclooxygenase 2.
Volume: 11
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8313388 | J:16958
First Author: Potter M
Year: 1994
Journal: Cancer Res
Title: Identification of two genes on chromosome 4 that determine resistance to plasmacytoma induction in mice.
Volume: 54
Issue: 4
Pages: 969-75
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27568978 | J:236390
First Author: Palacio L
Year: 2017
Journal: Oncogene
Title: Sustained p16INK4a expression is required to prevent IR-induced tumorigenesis in mice.
Volume: 36
Issue: 9
Pages: 1309-1314
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Publication
22109529 | J:220933
 
First Author: Lindsay CR
Year: 2011
Journal: Nat Commun
Title: P-Rex1 is required for efficient melanoblast migration and melanoma metastasis.
Volume: 2
Pages: 555
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31408372 | J:296135
First Author: Sessions GA
Year: 2019
Journal: FASEB J
Title: Controlled induction and targeted elimination of p16INK4a-expressing chondrocytes in cartilage explant culture.
Volume: 33
Issue: 11
Pages: 12364-12373
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Publication
30811968 | J:282283
 
First Author: Novais EJ
Year: 2019
Journal: Matrix Biol
Title: p16Ink4a deletion in cells of the intervertebral disc affects their matrix homeostasis and senescence associated secretory phenotype without altering onset of senescence.
Volume: 82
Pages: 54-70
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23508105 | J:204031
First Author: Kawagishi H
Year: 2013
Journal: Mol Cell Biol
Title: HuR maintains a replicative life span by repressing the ARF tumor suppressor.
Volume: 33
Issue: 10
Pages: 1886-900
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38731817 | J:348378
 
First Author: Jiang YN
Year: 2024
Journal: Int J Mol Sci
Title: Microcephaly Gene Mcph1 Deficiency Induces p19ARF-Dependent Cell Cycle Arrest and Senescence.
Volume: 25
Issue: 9
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15826307 | J:128558
First Author: Lavado A
Year: 2005
Journal: BMC Cell Biol
Title: A strategy to study tyrosinase transgenes in mouse melanocytes.
Volume: 6
Issue: 1
Pages: 18
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11259404 | J:143694
First Author: Sugihara T
Year: 2001
Journal: J Biol Chem
Title: Pex19p dampens the p19ARF-p53-p21WAF1 tumor suppressor pathway.
Volume: 276
Issue: 22
Pages: 18649-52
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11707341 | J:72891
First Author: Muscarella P
Year: 2001
Journal: Gene
Title: Identification and sequencing of the Syrian Golden hamster (Mesocricetus auratus) p16(INK4a) and p15(INK4b) cDNAs and their homozygous gene deletion in cheek pouch and pancreatic tumor cells.
Volume: 278
Issue: 1-2
Pages: 235-43
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7585567 | J:29767
First Author: Linardopoulos S
Year: 1995
Journal: Cancer Res
Title: Deletion and altered regulation of p16INK4a and p15INK4b in undifferentiated mouse skin tumors.
Volume: 55
Issue: 22
Pages: 5168-72
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8587124 | J:30410
First Author: Jiang P
Year: 1995
Journal: J Mol Evol
Title: Comparative analysis of Homo sapiens and Mus musculus cyclin-dependent kinase (CDK) inhibitor genes p16 (MTS1) and p15 (MTS2).
Volume: 41
Issue: 6
Pages: 795-802
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8934534 | J:36879
First Author: Herzog CR
Year: 1996
Journal: Oncogene
Title: Homozygous codeletion and differential decreased expression of p15INK4b, p16INK4a-alpha and p16INK4a-beta in mouse lung tumor cells.
Volume: 13
Issue: 9
Pages: 1885-91
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9094671 | J:39477
First Author: Lander JK
Year: 1997
Journal: J Virol
Title: Low-frequency loss of heterozygosity in Moloney murine leukemia virus-induced tumors in BRAKF1/J mice.
Volume: 71
Issue: 5
Pages: 3940-52
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9488045 | J:46150
First Author: Zhuang SM
Year: 1998
Journal: Oncogene
Title: Inactivations of p16INK4a-alpha, p16INK4a-beta and p15INK4b genes in 2',3'-dideoxycytidine- and 1,3-butadiene-induced murine lymphomas.
Volume: 16
Issue: 6
Pages: 803-8
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18056257 | J:132150
First Author: Bierings R
Year: 2008
Journal: J Biol Chem
Title: An endothelial cell genetic screen identifies the GTPase Rem2 as a suppressor of p19ARF expression that promotes endothelial cell proliferation and angiogenesis.
Volume: 283
Issue: 7
Pages: 4408-16
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19298843 | J:148713
First Author: Bruggeman SW
Year: 2009
Journal: Biochim Biophys Acta
Title: Bmi1 deficient neural stem cells have increased integrin dependent adhesion to self-secreted matrix.
Volume: 1790
Issue: 5
Pages: 351-60
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20308430 | J:158803
First Author: Herkert B
Year: 2010
Journal: J Cell Biol
Title: The Arf tumor suppressor protein inhibits Miz1 to suppress cell adhesion and induce apoptosis.
Volume: 188
Issue: 6
Pages: 905-18
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21708981 | J:174202
First Author: Rivera LB
Year: 2011
Journal: J Cell Biol
Title: SPARC promotes pericyte recruitment via inhibition of endoglin-dependent TGF-β1 activity.
Volume: 193
Issue: 7
Pages: 1305-19
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Publication
22904067 | J:199752
First Author: Petz M
Year: 2012
Journal: Nucleic Acids Res
Title: PDGF enhances IRES-mediated translation of Laminin B1 by cytoplasmic accumulation of La during epithelial to mesenchymal transition.
Volume: 40
Issue: 19
Pages: 9738-49
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24567370 | J:213678
First Author: Li C
Year: 2014
Journal: Mol Cell Biol
Title: Simultaneous gene editing by injection of mRNAs encoding transcription activator-like effector nucleases into mouse zygotes.
Volume: 34
Issue: 9
Pages: 1649-58
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18538737 | J:336733
First Author: Itahana K
Year: 2008
Journal: Cancer Cell
Title: Mitochondrial p32 is a critical mediator of ARF-induced apoptosis.
Volume: 13
Issue: 6
Pages: 542-53
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Publication
17110379 | J:127208
First Author: Tompkins VS
Year: 2007
Journal: J Biol Chem
Title: A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability.
Volume: 282
Issue: 2
Pages: 1322-33
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Publication
21996748 | J:186130
First Author: Whipple CA
Year: 2012
Journal: Oncogene
Title: A KrasG12D-driven genetic mouse model of pancreatic cancer requires glypican-1 for efficient proliferation and angiogenesis.
Volume: 31
Issue: 20
Pages: 2535-44
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