|  Help  |  About  |  Contact Us

Search our database by keyword

- or -

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 401 to 500 out of 848 for Htt

Category restricted to Publication (x)

<< First    < Previous  |  Next >    Last >>
0.04s

Categories

Category: Publication
« show all
Type Details Score
Publication
38096054 | J:348589
First Author: Chen JH
Year: 2023
Journal: Cell Rep
Title: Reduced lysosomal density in neuronal dendrites mediates deficits in synaptic plasticity in Huntington's disease.
Volume: 42
Issue: 12
Pages: 113573
•
•
•
•
•
Publication
17239451 | J:141673
First Author: Dorner JL
Year: 2007
Journal: Behav Brain Res
Title: Sex differences in behavior and striatal ascorbate release in the 140 CAG knock-in mouse model of Huntington's disease.
Volume: 178
Issue: 1
Pages: 90-7
•
•
•
•
•
Publication
30365550 | J:267707
First Author: Bertoglio D
Year: 2018
Journal: PLoS One
Title: MR-based spatial normalization improves [18F]MNI-659 PET regional quantification and detectability of disease effect in the Q175 mouse model of Huntington's disease.
Volume: 13
Issue: 10
Pages: e0206613
•
•
•
•
•
Publication
27559163 | J:353776
First Author: Hong Y
Year: 2016
Journal: J Neurosci
Title: Mutant Huntingtin Impairs BDNF Release from Astrocytes by Disrupting Conversion of Rab3a-GTP into Rab3a-GDP.
Volume: 36
Issue: 34
Pages: 8790-801
•
•
•
•
•
Publication
37726802 | J:340801
First Author: Li SH
Year: 2023
Journal: Mol Brain
Title: Comparison of Huntington's disease phenotype progression in male and female heterozygous FDNQ175 mice.
Volume: 16
Issue: 1
Pages: 67
•
•
•
•
•
Publication
28502806 | J:258623
 
First Author: Stefanko DP
Year: 2017
Journal: Neurobiol Dis
Title: Treadmill exercise delays the onset of non-motor behaviors and striatal pathology in the CAG140 knock-in mouse model of Huntington's disease.
Volume: 105
Pages: 15-32
•
•
•
•
•
Publication
19264961 | J:147083
First Author: Simmons DA
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice.
Volume: 106
Issue: 12
Pages: 4906-11
•
•
•
•
•
Publication
31132785 | J:284644
First Author: Nam H
Year: 2019
Journal: Neuropsychopharmacology
Title: Reduced nucleus accumbens enkephalins underlie vulnerability to social defeat stress.
Volume: 44
Issue: 11
Pages: 1876-1885
•
•
•
•
•
Publication
31418857 | J:352081
First Author: Hamilton J
Year: 2019
Journal: J Neurochem
Title: Mutant huntingtin fails to directly impair brain mitochondria.
Volume: 151
Issue: 6
Pages: 716-731
•
•
•
•
•
Publication
16230019 | J:105723
First Author: Graham RK
Year: 2006
Journal: Neurobiol Dis
Title: Levels of mutant huntingtin influence the phenotypic severity of Huntington disease in YAC128 mouse models.
Volume: 21
Issue: 2
Pages: 444-55
•
•
•
•
•
Publication
32144144 | J:288894
 
First Author: Glangetas C
Year: 2020
Journal: eNeuro
Title: Deficit in Motor Skill Consolidation-Dependent Synaptic Plasticity at Motor Cortex to Dorsolateral Striatum Synapses in a Mouse Model of Huntington's Disease.
Volume: 7
Issue: 2
•
•
•
•
•
Publication
32436947 | J:293809
First Author: Laroche M
Year: 2020
Journal: Hum Mol Genet
Title: Early deficits in olfaction are associated with structural and molecular alterations in the olfactory system of a Huntington disease mouse model.
Volume: 29
Issue: 13
Pages: 2134-2147
•
•
•
•
•
Publication
19915593 | J:155890
First Author: Okamoto S
Year: 2009
Journal: Nat Med
Title: Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin.
Volume: 15
Issue: 12
Pages: 1407-13
•
•
•
•
•
Publication
15843620 | J:98736
First Author: Van Raamsdonk JM
Year: 2005
Journal: J Neurosci
Title: Cognitive dysfunction precedes neuropathology and motor abnormalities in the YAC128 mouse model of Huntington's disease.
Volume: 25
Issue: 16
Pages: 4169-80
•
•
•
•
•
Publication
11358447 | J:69982
First Author: Guidetti P
Year: 2001
Journal: Exp Neurol
Title: Early degenerative changes in transgenic mice expressing mutant huntingtin involve dendritic abnormalities but no impairment of mitochondrial energy production.
Volume: 169
Issue: 2
Pages: 340-50
•
•
•
•
•
Publication
23678106 | J:198425
First Author: Ben M'Barek K
Year: 2013
Journal: J Neurosci
Title: Huntingtin mediates anxiety/depression-related behaviors and hippocampal neurogenesis.
Volume: 33
Issue: 20
Pages: 8608-20
•
•
•
•
•
Publication
17708681 | J:125228
First Author: Lee JM
Year: 2007
Journal: PLoS Genet
Title: Unbiased gene expression analysis implicates the huntingtin polyglutamine tract in extra-mitochondrial energy metabolism.
Volume: 3
Issue: 8
Pages: e135
•
•
•
•
•
Publication
8757264 | J:34936
First Author: Bhide PG
Year: 1996
Journal: J Neurosci
Title: Expression of normal and mutant huntingtin in the developing brain.
Volume: 16
Issue: 17
Pages: 5523-35
•
•
•
•
•
Publication
16256944 | J:102831
First Author: Omi K
Year: 2005
Journal: Biochem Biophys Res Commun
Title: siRNA-mediated inhibition of endogenous Huntington disease gene expression induces an aberrant configuration of the ER network in vitro.
Volume: 338
Issue: 2
Pages: 1229-35
•
•
•
•
•
Publication
7662892 | J:29604
First Author: Tatter SB
Year: 1995
Journal: Neuroreport
Title: Effects of striatal excitotoxicity on huntingtin-like immunoreactivity.
Volume: 6
Issue: 8
Pages: 1125-9
•
•
•
•
•
Publication
10037472 | J:53133
First Author: Metzler M
Year: 1999
Journal: J Neurochem
Title: Life without huntingtin: normal differentiation into functional neurons.
Volume: 72
Issue: 3
Pages: 1009-18
•
•
•
•
•
Publication
10754231 | J:62396
First Author: Guidetti P
Year: 2000
Journal: Neurosci Lett
Title: Early kynurenergic impairment in Huntington's disease and in a transgenic animal model.
Volume: 283
Issue: 3
Pages: 233-5
•
•
•
•
•
Publication
10799690 | J:61819
First Author: Pérez-Severiano F
Year: 2000
Journal: Brain Res
Title: Striatal oxidative damage parallels the expression of a neurological phenotype in mice transgenic for the mutation of Huntington's disease.
Volume: 862
Issue: 1-2
Pages: 234-7
•
•
•
•
•
Publication
11013077 | J:65121
First Author: Matsuyama N
Year: 2000
Journal: Genomics
Title: Identification and characterization of the miniature pig Huntington's disease gene homolog: evidence for conservation and polymorphism in the CAG triplet repeat.
Volume: 69
Issue: 1
Pages: 72-85
•
•
•
•
•
Publication
1284592 | J:3574
First Author: Goldberg YP
Year: 1992
Journal: Hum Mol Genet
Title: Cloning and mapping of the alpha-adducin gene close to D4S95 and assessment of its relationship to Huntington disease.
Volume: 1
Issue: 9
Pages: 669-75
•
•
•
•
•
Publication
8401589 | J:42662
First Author: Andrew SE
Year: 1993
Journal: Nat Genet
Title: The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease.
Volume: 4
Issue: 4
Pages: 398-403
•
•
•
•
•
Publication
8845840 | J:32989
First Author: Wood JD
Year: 1996
Journal: Hum Mol Genet
Title: Partial characterisation of murine huntingtin and apparent variations in the subcellular localisation of huntingtin in human, mouse and rat brain.
Volume: 5
Issue: 4
Pages: 481-7
•
•
•
•
•
Publication
8824873 | J:31281
First Author: Goldberg YP
Year: 1996
Journal: Hum Mol Genet
Title: Absence of disease phenotype and intergenerational stability of the CAG repeat in transgenic mice expressing the human Huntington disease transcript.
Volume: 5
Issue: 2
Pages: 177-85
•
•
•
•
•
Publication
8968738 | J:37964
First Author: Hodgson JG
Year: 1996
Journal: Hum Mol Genet
Title: Human huntingtin derived from YAC transgenes compensates for loss of murine huntingtin by rescue of the embryonic lethal phenotype.
Volume: 5
Issue: 12
Pages: 1875-85
•
•
•
•
•
Publication
9017261 | J:37717
First Author: Casanova E
Year: 1996
Journal: Brain Res
Title: Identification of a long huntingtin mRNA transcript in mouse brain.
Volume: 743
Issue: 1-2
Pages: 320-3
•
•
•
•
•
Publication
9300654 | J:42616
First Author: Bates GP
Year: 1997
Journal: Hum Mol Genet
Title: Transgenic models of Huntington's disease.
Volume: 6
Issue: 10
Pages: 1633-7
•
•
•
•
•
Publication
9328479 | J:43794
First Author: Sathasivam K
Year: 1997
Journal: Hum Mol Genet
Title: Aberrant processing of the Fugu HD (FrHD) mRNA in mouse cells and in transgenic mice.
Volume: 6
Issue: 12
Pages: 2141-9
•
•
•
•
•
Publication
10098399 | J:53101
First Author: Perutz MF
Year: 1999
Journal: Trends Biochem Sci
Title: Glutamine repeats and neurodegenerative diseases: molecular aspects.
Volume: 24
Issue: 2
Pages: 58-63
•
•
•
•
•
Publication
10196370 | J:54554
First Author: Sathasivam K
Year: 1999
Journal: Hum Mol Genet
Title: Formation of polyglutamine inclusions in non-CNS tissue.
Volume: 8
Issue: 5
Pages: 813-22
•
•
•
•
•
Publication
10434294 | J:56819
First Author: Sathasivam K
Year: 1999
Journal: Philos Trans R Soc Lond B Biol Sci
Title: Transgenic models of Huntington's disease.
Volume: 354
Issue: 1386
Pages: 963-9
•
•
•
•
•
Publication
10434303 | J:56821
First Author: Reddy PH
Year: 1999
Journal: Philos Trans R Soc Lond B Biol Sci
Title: Transgenic mice expressing mutated full-length HD cDNA: a paradigm for locomotor changes and selective neuronal loss in Huntington's disease.
Volume: 354
Issue: 1386
Pages: 1035-45
•
•
•
•
•
Publication
11932021 | J:75817
First Author: Rubinsztein DC
Year: 2002
Journal: Trends Genet
Title: Lessons from animal models of Huntington's disease.
Volume: 18
Issue: 4
Pages: 202-9
•
•
•
•
•
Publication
16289942 | J:105308
First Author: Jeong SJ
Year: 2006
Journal: Int J Dev Neurosci
Title: Huntingtin is localized in the nucleus during preimplanatation embryo development in mice.
Volume: 24
Issue: 1
Pages: 81-5
•
•
•
•
•
Publication
19487684 | J:150069
First Author: Nekooki-Machida Y
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Distinct conformations of in vitro and in vivo amyloids of huntingtin-exon1 show different cytotoxicity.
Volume: 106
Issue: 24
Pages: 9679-84
•
•
•
•
•
Publication
20403078 | J:161823
First Author: Oliveira JM
Year: 2010
Journal: J Neurochem
Title: Nature and cause of mitochondrial dysfunction in Huntington's disease: focusing on huntingtin and the striatum.
Volume: 114
Issue: 1
Pages: 1-12
•
•
•
•
•
Publication
21459327 | J:172244
First Author: Hult S
Year: 2011
Journal: Cell Metab
Title: Mutant huntingtin causes metabolic imbalance by disruption of hypothalamic neurocircuits.
Volume: 13
Issue: 4
Pages: 428-439
•
•
•
•
•
Publication
21954231 | J:178870
First Author: Lee H
Year: 2012
Journal: Hum Mol Genet
Title: IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux.
Volume: 21
Issue: 1
Pages: 101-14
•
•
•
•
•
Publication
23365139 | J:194319
First Author: Sontag EM
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Exogenous delivery of chaperonin subunit fragment ApiCCT1 modulates mutant Huntingtin cellular phenotypes.
Volume: 110
Issue: 8
Pages: 3077-82
•
•
•
•
•
Publication
17611284 | J:209492
First Author: Anne SL
Year: 2007
Journal: J Neurosci
Title: Phosphorylation of huntingtin by cyclin-dependent kinase 5 is induced by DNA damage and regulates wild-type and mutant huntingtin toxicity in neurons.
Volume: 27
Issue: 27
Pages: 7318-28
•
•
•
•
•
Publication
25205111 | J:217211
First Author: Nath S
Year: 2015
Journal: Hum Mol Genet
Title: A huntingtin-mediated fast stress response halting endosomal trafficking is defective in Huntington's disease.
Volume: 24
Issue: 2
Pages: 450-62
•
•
•
•
•
Publication
25368120 | J:217418
First Author: Brandstaetter H
Year: 2014
Journal: Dis Model Mech
Title: Huntingtin is required for ER-to-Golgi transport and for secretory vesicle fusion at the plasma membrane.
Volume: 7
Issue: 12
Pages: 1335-40
•
•
•
•
•
Publication
29912367 | J:274658
First Author: Ko J
Year: 2018
Journal: Hum Mol Genet
Title: Identification of distinct conformations associated with monomers and fibril assemblies of mutant huntingtin.
Volume: 27
Issue: 13
Pages: 2330-2343
•
•
•
•
•
Publication
22956985 | J:315225
First Author: Neveklovska M
Year: 2012
Journal: J Huntingtons Dis
Title: Deletion of the huntingtin proline-rich region does not significantly affect normal huntingtin function in mice.
Volume: 1
Issue: 1
Pages: 71-87
•
•
•
•
•
Publication
25004085 | J:318278
 
First Author: Frederick NM
Year: 2014
Journal: Neurochem Int
Title: Dysregulation of system xc(-) expression induced by mutant huntingtin in a striatal neuronal cell line and in R6/2 mice.
Volume: 76
Pages: 59-69
•
•
•
•
•
Publication
37664244 | J:340523
 
First Author: Xu C
Year: 2023
Journal: Front Mol Neurosci
Title: Altered exocytosis of inhibitory synaptic vesicles at single presynaptic terminals of cultured striatal neurons in a knock-in mouse model of Huntington's disease.
Volume: 16
Pages: 1175522
•
•
•
•
•
Publication
11035034 | J:277863
First Author: Peters MF
Year: 2001
Journal: J Biol Chem
Title: Isolation of a 40-kDa Huntingtin-associated protein.
Volume: 276
Issue: 5
Pages: 3188-94
•
•
•
•
•
Publication
28469074 | J:244563
 
First Author: Ma Q
Year: 2017
Journal: JCI Insight
Title: SorCS2-mediated NR2A trafficking regulates motor deficits in Huntington's disease.
Volume: 2
Issue: 9
•
•
•
•
•
Publication
9398841 | J:44391
First Author: White JK
Year: 1997
Journal: Nat Genet
Title: Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion.
Volume: 17
Issue: 4
Pages: 404-10
•
•
•
•
•
Publication
12217951 | J:79126
First Author: Fossale E
Year: 2002
Journal: Hum Mol Genet
Title: Identification of a presymptomatic molecular phenotype in Hdh CAG knock-in mice.
Volume: 11
Issue: 19
Pages: 2233-41
•
•
•
•
•
Publication
21632937 | J:173377
First Author: Saavedra A
Year: 2011
Journal: J Neurosci
Title: Striatal-enriched protein tyrosine phosphatase expression and activity in Huntington's disease: a STEP in the resistance to excitotoxicity.
Volume: 31
Issue: 22
Pages: 8150-62
•
•
•
•
•
Publication
21403395 | J:172008
First Author: Lin YS
Year: 2011
Journal: J Clin Invest
Title: Dysregulated brain creatine kinase is associated with hearing impairment in mouse models of Huntington disease.
Volume: 121
Issue: 4
Pages: 1519-23
•
•
•
•
•
Publication
30587542 | J:271675
First Author: Lin MS
Year: 2019
Journal: J Neurosci
Title: Degeneration of ipRGCs in Mouse Models of Huntington's Disease Disrupts Non-Image-Forming Behaviors Before Motor Impairment.
Volume: 39
Issue: 8
Pages: 1505-1524
•
•
•
•
•
Publication
11145989 | J:67773
First Author: Morton AJ
Year: 2001
Journal: J Neurochem
Title: Progressive depletion of complexin II in a transgenic mouse model of Huntington's disease.
Volume: 76
Issue: 1
Pages: 166-72
•
•
•
•
•
Publication
29534157 | J:263425
First Author: Galvan L
Year: 2018
Journal: Brain
Title: The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin.
Volume: 141
Issue: 5
Pages: 1434-1454
•
•
•
•
•
Publication
35366418 | J:325617
First Author: Ma X
Year: 2022
Journal: Cell
Title: CCT2 is an aggrephagy receptor for clearance of solid protein aggregates.
Volume: 185
Issue: 8
Pages: 1325-1345.e22
•
•
•
•
•
Publication
34648564 | J:311740
First Author: Heikkinen T
Year: 2021
Journal: PLoS One
Title: Global Rhes knockout in the Q175 Huntington's disease mouse model.
Volume: 16
Issue: 10
Pages: e0258486
•
•
•
•
•
Publication
8528205 | J:26500
First Author: Schmitt I
Year: 1995
Journal: Hum Mol Genet
Title: Expression of the Huntington disease gene in rodents: cloning the rat homologue and evidence for downregulation in non-neuronal tissues during development.
Volume: 4
Issue: 7
Pages: 1173-82
•
•
•
•
•
Publication
8264627 | J:16058
First Author: Kozak UC
Year: 1994
Journal: Mol Cell Biol
Title: An upstream enhancer regulating brown-fat-specific expression of the mitochondrial uncoupling protein gene.
Volume: 14
Issue: 1
Pages: 59-67
•
•
•
•
•
Publication
25411494 | J:217389
First Author: Tallaksen-Greene SJ
Year: 2014
Journal: J Neurosci
Title: Differential effects of delayed aging on phenotype and striatal pathology in a murine model of Huntington disease.
Volume: 34
Issue: 47
Pages: 15658-68
•
•
•
•
•
Publication
25180603 | J:217639
First Author: Brito V
Year: 2014
Journal: J Clin Invest
Title: Neurotrophin receptor p75(NTR) mediates Huntington's disease-associated synaptic and memory dysfunction.
Volume: 124
Issue: 10
Pages: 4411-28
•
•
•
•
•
Publication
20053912 | J:164039
First Author: Ribeiro FM
Year: 2010
Journal: J Neurosci
Title: Metabotropic glutamate receptor-mediated cell signaling pathways are altered in a mouse model of Huntington's disease.
Volume: 30
Issue: 1
Pages: 316-24
•
•
•
•
•
Publication
24282028 | J:207093
First Author: Ribeiro FM
Year: 2014
Journal: Hum Mol Genet
Title: Metabotropic glutamate receptor 5 knockout promotes motor and biochemical alterations in a mouse model of Huntington's disease.
Volume: 23
Issue: 8
Pages: 2030-42
•
•
•
•
•
Publication
17124493 | J:200423
First Author: Zhang Y
Year: 2006
Journal: EMBO J
Title: Huntingtin inhibits caspase-3 activation.
Volume: 25
Issue: 24
Pages: 5896-906
•
•
•
•
•
Publication
15496430 | J:94581
First Author: Dragatsis I
Year: 2004
Journal: Hum Mol Genet
Title: Huntingtin-associated protein 1 (Hap1) mutant mice bypassing the early postnatal lethality are neuroanatomically normal and fertile but display growth retardation.
Volume: 13
Issue: 24
Pages: 3115-25
•
•
•
•
•
Publication
10581038 | J:58797
First Author: Manley K
Year: 1999
Journal: Nat Genet
Title: Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice.
Volume: 23
Issue: 4
Pages: 471-3
•
•
•
•
•
Publication
12554681 | J:81666
First Author: Wheeler VC
Year: 2003
Journal: Hum Mol Genet
Title: Mismatch repair gene Msh2 modifies the timing of early disease in Hdh(Q111) striatum.
Volume: 12
Issue: 3
Pages: 273-81
•
•
•
•
•
Publication
24302884 | J:205270
First Author: Mielcarek M
Year: 2013
Journal: PLoS Biol
Title: HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration.
Volume: 11
Issue: 11
Pages: e1001717
•
•
•
•
•
Publication
17065224 | J:146707
First Author: Cyr M
Year: 2006
Journal: FASEB J
Title: Dopamine enhances motor and neuropathological consequences of polyglutamine expanded huntingtin.
Volume: 20
Issue: 14
Pages: 2541-3
•
•
•
•
•
Publication
32513388 | J:290430
   
First Author: Moreno-Delgado D
Year: 2020
Journal: Elife
Title: Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease.
Volume: 9
•
•
•
•
•
Publication
34793694 | J:322642
First Author: Capizzi M
Year: 2022
Journal: Neuron
Title: Developmental defects in Huntington's disease show that axonal growth and microtubule reorganization require NUMA1.
Volume: 110
Issue: 1
Pages: 36-50.e5
•
•
•
•
•
Publication
31790427 | J:287860
First Author: Comella Bolla A
Year: 2019
Journal: PLoS One
Title: CD200 is up-regulated in R6/1 transgenic mouse model of Huntington's disease.
Volume: 14
Issue: 12
Pages: e0224901
•
•
•
•
•
Publication
18829967 | J:143463
First Author: Paoletti P
Year: 2008
Journal: J Neurosci
Title: Dopaminergic and glutamatergic signaling crosstalk in Huntington's disease neurodegeneration: the role of p25/cyclin-dependent kinase 5.
Volume: 28
Issue: 40
Pages: 10090-101
•
•
•
•
•
Publication
36029989 | J:328548
 
First Author: Rodríguez-Urgellés E
Year: 2022
Journal: Neurobiol Dis
Title: Postnatal Foxp2 regulates early psychiatric-like phenotypes and associated molecular alterations in the R6/1 transgenic mouse model of Huntington's disease.
Volume: 173
Pages: 105854
•
•
•
•
•
Publication
29355642 | J:315885
 
First Author: Weber JJ
Year: 2018
Journal: Neuropharmacology
Title: Calpastatin ablation aggravates the molecular phenotype in cell and animal models of Huntington disease.
Volume: 133
Pages: 94-106
•
•
•
•
•
Publication
22341442 | J:181549
First Author: Liu CR
Year: 2012
Journal: Cell
Title: Spt4 is selectively required for transcription of extended trinucleotide repeats.
Volume: 148
Issue: 4
Pages: 690-701
•
•
•
•
•
Publication
28970536 | J:255756
First Author: Neueder A
Year: 2017
Journal: Sci Rep
Title: HSF1-dependent and -independent regulation of the mammalian in vivo heat shock response and its impairment in Huntington's disease mouse models.
Volume: 7
Issue: 1
Pages: 12556
•
•
•
•
•
Publication
17018277 | J:116058
First Author: Cui L
Year: 2006
Journal: Cell
Title: Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.
Volume: 127
Issue: 1
Pages: 59-69
•
•
•
•
•
Publication
12881722 | J:243542
First Author: Zuccato C
Year: 2003
Journal: Nat Genet
Title: Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes.
Volume: 35
Issue: 1
Pages: 76-83
•
•
•
•
•
Publication
18625318 | J:147008
First Author: Lorincz MT
Year: 2009
Journal: Mol Cell Neurosci
Title: Expanded CAG repeats in the murine Huntington's disease gene increases neuronal differentiation of embryonic and neural stem cells.
Volume: 40
Issue: 1
Pages: 1-13
•
•
•
•
•
Publication
18625748 | J:138558
First Author: Björkqvist M
Year: 2008
Journal: J Exp Med
Title: A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease.
Volume: 205
Issue: 8
Pages: 1869-77
•
•
•
•
•
Publication
20945165 | J:175960
First Author: Switonski PM
Year: 2011
Journal: Neuromolecular Med
Title: Mouse ataxin-3 functional knock-out model.
Volume: 13
Issue: 1
Pages: 54-65
•
•
•
•
•
Publication
21785217 | J:176008
First Author: Labbadia J
Year: 2011
Journal: J Clin Invest
Title: Altered chromatin architecture underlies progressive impairment of the heat shock response in mouse models of Huntington disease.
Volume: 121
Issue: 8
Pages: 3306-19
•
•
•
•
•
Publication
26247199 | J:228819
First Author: Budworth H
Year: 2015
Journal: PLoS Genet
Title: Suppression of Somatic Expansion Delays the Onset of Pathophysiology in a Mouse Model of Huntington's Disease.
Volume: 11
Issue: 8
Pages: e1005267
•
•
•
•
•
Publication
23861892 | J:204285
First Author: Proenca CC
Year: 2013
Journal: PLoS One
Title: Atg4b-dependent autophagic flux alleviates Huntington's disease progression.
Volume: 8
Issue: 7
Pages: e68357
•
•
•
•
•
Publication
33601422 | J:339888
First Author: Cozzolino F
Year: 2021
Journal: Hum Mol Genet
Title: ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease.
Volume: 30
Issue: 13
Pages: 1175-1187
•
•
•
•
•
Publication
24955833 | J:216828
First Author: Menalled LB
Year: 2014
Journal: PLoS One
Title: Genetic deletion of transglutaminase 2 does not rescue the phenotypic deficits observed in R6/2 and zQ175 mouse models of Huntington's disease.
Volume: 9
Issue: 6
Pages: e99520
•
•
•
•
•
Publication
26195796 | J:226055
First Author: Ahmed I
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Huntington's disease: Neural dysfunction linked to inositol polyphosphate multikinase.
Volume: 112
Issue: 31
Pages: 9751-6
•
•
•
•
•
Publication
29688337 | J:263782
First Author: Di Pardo A
Year: 2018
Journal: Hum Mol Genet
Title: Stimulation of S1PR5 with A-971432, a selective agonist, preserves blood-brain barrier integrity and exerts therapeutic effect in an animal model of Huntington's disease.
Volume: 27
Issue: 14
Pages: 2490-2501
•
•
•
•
•
Publication
21969577 | J:177450
First Author: Hu Y
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Transcriptional modulator H2A histone family, member Y (H2AFY) marks Huntington disease activity in man and mouse.
Volume: 108
Issue: 41
Pages: 17141-6
•
•
•
•
•
Publication
36044851 | J:328314
First Author: Benraiss A
Year: 2022
Journal: Cell Rep
Title: A TCF7L2-responsive suppression of both homeostatic and compensatory remyelination in Huntington disease mice.
Volume: 40
Issue: 9
Pages: 111291
•
•
•
•
•
Publication
25205109 | J:217212
First Author: Gratuze M
Year: 2015
Journal: Hum Mol Genet
Title: Tau hyperphosphorylation and deregulation of calcineurin in mouse models of Huntington's disease.
Volume: 24
Issue: 1
Pages: 86-99
•
•
•
•
•
Publication
34880223 | J:318006
First Author: Sönmez A
Year: 2021
Journal: Cell Death Dis
Title: Nucleolar stress controls mutant Huntington toxicity and monitors Huntington's disease progression.
Volume: 12
Issue: 12
Pages: 1139
•
•
•
•
•
Publication
25143394 | J:216514
First Author: Blum D
Year: 2015
Journal: Hum Mol Genet
Title: Mutant huntingtin alters Tau phosphorylation and subcellular distribution.
Volume: 24
Issue: 1
Pages: 76-85
•
•
•
•
•
Publication
31068790 | J:284337
 
First Author: Di Pardo A
Year: 2019
Journal: Front Mol Neurosci
Title: Stimulation of Sphingosine Kinase 1 (SPHK1) Is Beneficial in a Huntington's Disease Pre-clinical Model.
Volume: 12
Pages: 100
•
•
•
•
•
Publication
20497470 | J:163791
First Author: Leon R
Year: 2010
Journal: Eur J Neurosci
Title: BimEL as a possible molecular link between proteasome dysfunction and cell death induced by mutant huntingtin.
Volume: 31
Issue: 11
Pages: 1915-25
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom