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Search results 401 to 500 out of 659 for Jak2

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Category: Publication
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Type Details Score
Publication
15475610 | -
First Author: Sandberg EM
Year: 2004
Journal: Cell Biochem Biophys
Title: Jak2 tyrosine kinase: a true jak of all trades?
Volume: 41
Issue: 2
Pages: 207-32
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Publication
17389152 | -
First Author: Hsu HC
Year: 2007
Journal: J Chin Med Assoc
Title: Pathogenetic role of JAK2 V617F mutation in chronic myeloproliferative disorders.
Volume: 70
Issue: 3
Pages: 89-93
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Publication
24354892 | J:210554
First Author: Varghese LN
Year: 2014
Journal: Biochem J
Title: Mechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analyses.
Volume: 458
Issue: 2
Pages: 395-405
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Publication
21368206 | J:170821
First Author: Berry DC
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Signaling by vitamin A and retinol-binding protein regulates gene expression to inhibit insulin responses.
Volume: 108
Issue: 11
Pages: 4340-5
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Publication
30463063 | J:328639
First Author: Swaminathan M
Year: 2019
Journal: Acta Haematol
Title: Unique Case of Myeloproliferative Neoplasm with Two Rare Clonal Abnormalities: Rare JAK2 Exon 12 Mutation and Rare e14a3 (b3a3) BCR/ABL Fusion Transcript.
Volume: 141
Issue: 1
Pages: 23-27
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Publication
21841788 | -
First Author: Ungureanu D
Year: 2011
Journal: Nat Struct Mol Biol
Title: The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling.
Volume: 18
Issue: 9
Pages: 971-6
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Publication
17466371 | -
First Author: Karow A
Year: 2008
Journal: Leuk Res
Title: JAK2 mutations other than V617F: a novel mutation and mini review.
Volume: 32
Issue: 2
Pages: 365-6
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Publication
31709318 | J:285383
First Author: Sano S
Year: 2019
Journal: JACC Basic Transl Sci
Title: JAK2 V617F -Mediated Clonal Hematopoiesis Accelerates Pathological Remodeling in Murine Heart Failure.
Volume: 4
Issue: 6
Pages: 684-697
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Publication
21457752 | -
First Author: Helmer RA
Year: 2011
Journal: Mol Cell Endocrinol
Title: Prolactin induces Jak2 phosphorylation of RUSHY195.
Volume: 338
Issue: 1-2
Pages: 79-83
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Publication
19290934 | -
First Author: Ghoreschi K
Year: 2009
Journal: Immunol Rev
Title: Janus kinases in immune cell signaling.
Volume: 228
Issue: 1
Pages: 273-87
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Publication
21533163 | -
First Author: Sanz A
Year: 2011
Journal: PLoS One
Title: Analysis of Jak2 catalytic function by peptide microarrays: the role of the JH2 domain and V617F mutation.
Volume: 6
Issue: 4
Pages: e18522
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Publication
9573010 | -
First Author: Chin H
Year: 1998
Journal: Blood
Title: Lyn physically associates with the erythropoietin receptor and may play a role in activation of the Stat5 pathway.
Volume: 91
Issue: 10
Pages: 3734-45
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Publication
11923481 | -
First Author: Bahrenberg G
Year: 2002
Journal: Mol Endocrinol
Title: Identification of the critical sequence elements in the cytoplasmic domain of leptin receptor isoforms required for Janus kinase/signal transducer and activator of transcription activation by receptor heterodimers.
Volume: 16
Issue: 4
Pages: 859-72
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Publication
19783980 | -
First Author: Dawson MA
Year: 2009
Journal: Nature
Title: JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin.
Volume: 461
Issue: 7265
Pages: 819-22
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Publication
16810614 | -
First Author: Bellucci S
Year: 2006
Journal: Semin Thromb Hemost
Title: The role of JAK2 V617F mutation, spontaneous erythropoiesis and megakaryocytopoiesis, hypersensitive platelets, activated leukocytes, and endothelial cells in the etiology of thrombotic manifestations in polycythemia vera and essential thrombocythemia.
Volume: 32
Issue: 4 Pt 2
Pages: 381-98
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Publication
16239216 | -
First Author: Staerk J
Year: 2005
Journal: J Biol Chem
Title: JAK1 and Tyk2 activation by the homologous polycythemia vera JAK2 V617F mutation: cross-talk with IGF1 receptor.
Volume: 280
Issue: 51
Pages: 41893-9
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Publication
20098430 | J:157074
First Author: Guilluy C
Year: 2010
Journal: Nat Med
Title: The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure.
Volume: 16
Issue: 2
Pages: 183-90
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8068943 | -
First Author: Miura O
Year: 1994
Journal: Blood
Title: Erythropoietin induces association of the JAK2 protein tyrosine kinase with the erythropoietin receptor in vivo.
Volume: 84
Issue: 5
Pages: 1501-7
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Publication
9343427 | -
First Author: Rui L
Year: 1997
Journal: Mol Cell Biol
Title: Identification of SH2-Bbeta as a substrate of the tyrosine kinase JAK2 involved in growth hormone signaling.
Volume: 17
Issue: 11
Pages: 6633-44
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Publication
12552091 | -
First Author: Leung KC
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Estrogen inhibits GH signaling by suppressing GH-induced JAK2 phosphorylation, an effect mediated by SOCS-2.
Volume: 100
Issue: 3
Pages: 1016-21
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Publication
15143188 | -
First Author: Feener EP
Year: 2004
Journal: Mol Cell Biol
Title: Tyrosine phosphorylation of Jak2 in the JH2 domain inhibits cytokine signaling.
Volume: 24
Issue: 11
Pages: 4968-78
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Publication
9363897 | -
First Author: Yamauchi T
Year: 1997
Journal: Nature
Title: Tyrosine phosphorylation of the EGF receptor by the kinase Jak2 is induced by growth hormone.
Volume: 390
Issue: 6655
Pages: 91-6
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Publication
15988755 | -
First Author: Huang HM
Year: 2005
Journal: J Cell Biochem
Title: Simultaneous activation of JAK1 and JAK2 confers IL-3 independent growth on Ba/F3 pro-B cells.
Volume: 96
Issue: 2
Pages: 361-75
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10757801 | -
First Author: Rui L
Year: 2000
Journal: Mol Cell Biol
Title: Differential binding to and regulation of JAK2 by the SH2 domain and N-terminal region of SH2-bbeta.
Volume: 20
Issue: 9
Pages: 3168-77
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Publication
8702385 | -
First Author: Fuhrer DK
Year: 1996
Journal: Biochem Biophys Res Commun
Title: Complex formation of JAK2 with PP2A, P13K, and Yes in response to the hematopoietic cytokine interleukin-11.
Volume: 224
Issue: 2
Pages: 289-96
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Publication
- | J:72448
     
First Author: Sjoling A
Year: 2001
Journal: MGI Direct Data Submission
Title: Analysis of chromosomal aberrations involving rat chromosome 1q31-q51 in a DMBA-induced rat fibrosarcoma cell line: amplification and over-expression of Jak2
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8611693 | -
First Author: Weiler SR
Year: 1996
Journal: Blood
Title: JAK2 is associated with the c-kit proto-oncogene product and is phosphorylated in response to stem cell factor.
Volume: 87
Issue: 9
Pages: 3688-93
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7499845 | -
First Author: Szente BE
Year: 1995
Journal: J Immunol
Title: Identification of IFN-gamma receptor binding sites for JAK2 and enhancement of binding by IFN-gamma and its C-terminal peptide IFN-gamma(95-133).
Volume: 155
Issue: 12
Pages: 5617-22
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16914724 | -
First Author: Kurzer JH
Year: 2006
Journal: Mol Cell Biol
Title: Binding of SH2-B family members within a potential negative regulatory region maintains JAK2 in an active state.
Volume: 26
Issue: 17
Pages: 6381-94
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Publication
9111009 | -
First Author: Hackett RH
Year: 1997
Journal: J Biol Chem
Title: Mapping of a cytoplasmic domain of the human growth hormone receptor that regulates rates of inactivation of Jak2 and Stat proteins.
Volume: 272
Issue: 17
Pages: 11128-32
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Publication
22019628 | J:191404
First Author: Majumder A
Year: 2012
Journal: Exp Hematol
Title: A46, a benzothiophene-derived compound, suppresses Jak2-mediated pathologic cell growth.
Volume: 40
Issue: 1
Pages: 22-34
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22796437 | J:188525
First Author: Kirabo A
Year: 2012
Journal: Am J Pathol
Title: The small molecule inhibitor G6 significantly reduces bone marrow fibrosis and the mutant burden in a mouse model of Jak2-mediated myelofibrosis.
Volume: 181
Issue: 3
Pages: 858-65
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27401345 | J:236468
First Author: Sashida G
Year: 2016
Journal: J Exp Med
Title: The loss of Ezh2 drives the pathogenesis of myelofibrosis and sensitizes tumor-initiating cells to bromodomain inhibition.
Volume: 213
Issue: 8
Pages: 1459-77
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17133099 | -
First Author: Levine RL
Year: 2007
Journal: Curr Opin Hematol
Title: JAK-2 mutations and their relevance to myeloproliferative disease.
Volume: 14
Issue: 1
Pages: 43-7
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11340172 | J:69504
First Author: Yamada M
Year: 2001
Journal: Mol Cell Biol
Title: Loss of hippocampal CA3 pyramidal neurons in mice lacking STAM1.
Volume: 21
Issue: 11
Pages: 3807-19
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34497325 | J:319703
First Author: Shinoda D
Year: 2022
Journal: Leukemia
Title: Insufficiency of non-canonical PRC1 synergizes with JAK2V617F in the development of myelofibrosis.
Volume: 36
Issue: 2
Pages: 452-463
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25395421 | J:330937
First Author: Kameda T
Year: 2015
Journal: Blood
Title: Loss of TET2 has dual roles in murine myeloproliferative neoplasms: disease sustainer and disease accelerator.
Volume: 125
Issue: 2
Pages: 304-15
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35286385 | J:326022
First Author: Li L
Year: 2022
Journal: Blood
Title: HMGA1 chromatin regulators induce transcriptional networks involved in GATA2 and proliferation during MPN progression.
Volume: 139
Issue: 18
Pages: 2797-2815
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18334677 | J:135993
First Author: Xing S
Year: 2008
Journal: Blood
Title: Transgenic expression of JAK2V617F causes myeloproliferative disorders in mice.
Volume: 111
Issue: 10
Pages: 5109-17
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32294178 | J:301286
First Author: Matsuura S
Year: 2020
Journal: Blood
Title: Adhesion to fibronectin via α5β1 integrin supports expansion of the megakaryocyte lineage in primary myelofibrosis.
Volume: 135
Issue: 25
Pages: 2286-2291
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24391943 | J:209831
First Author: Jin X
Year: 2013
Journal: PLoS One
Title: Generation of a new congenic mouse strain with enhanced chymase expression in mast cells.
Volume: 8
Issue: 12
Pages: e84340
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31511238 | J:282109
First Author: Rao TN
Year: 2019
Journal: Blood
Title: JAK2-mutant hematopoietic cells display metabolic alterations that can be targeted to treat myeloproliferative neoplasms.
Volume: 134
Issue: 21
Pages: 1832-1846
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15561980 | -
First Author: Horvath CM
Year: 2004
Journal: Sci STKE
Title: The Jak-STAT pathway stimulated by interferon gamma.
Volume: 2004
Issue: 260
Pages: tr8
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12446783 | J:80617
First Author: Yamada M
Year: 2002
Journal: Mol Cell Biol
Title: Signal-transducing adaptor molecules STAM1 and STAM2 are required for T-cell development and survival.
Volume: 22
Issue: 24
Pages: 8648-58
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21187078 | -
First Author: Lim J
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Solution structure of UIM and interaction of tandem ubiquitin binding domains in STAM1 with ubiquitin.
Volume: 405
Issue: 1
Pages: 24-30
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26101075 | J:226940
 
First Author: Kapuralin K
Year: 2015
Journal: Mol Cell Neurosci
Title: STAM2, a member of the endosome-associated complex ESCRT-0 is highly expressed in neurons.
Volume: 67
Pages: 104-15
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9407053 | J:44869
First Author: Asao H
Year: 1997
Journal: J Biol Chem
Title: Hrs is associated with STAM, a signal-transducing adaptor molecule. Its suppressive effect on cytokine-induced cell growth.
Volume: 272
Issue: 52
Pages: 32785-91
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11728436 | -
First Author: Lohi O
Year: 2001
Journal: FEBS Lett
Title: STAM/EAST/Hbp adapter proteins--integrators of signalling pathways.
Volume: 508
Issue: 3
Pages: 287-90
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10899310 | -
First Author: Endo K
Year: 2000
Journal: FEBS Lett
Title: STAM2, a new member of the STAM family, binding to the Janus kinases.
Volume: 477
Issue: 1-2
Pages: 55-61
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29296743 | J:303417
First Author: Ueda K
Year: 2017
Journal: Blood Adv
Title: Hmga2 collaborates with JAK2V617F in the development of myeloproliferative neoplasms.
Volume: 1
Issue: 15
Pages: 1001-1015
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36873934 | J:343719
 
First Author: Aini W
Year: 2023
Journal: Front Genet
Title: Exploration and identification of anoikis-related genes in polycythemia vera.
Volume: 14
Pages: 1139351
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28550162 | J:244489
First Author: Kim E
Year: 2017
Journal: J Exp Med
Title: Rb family proteins enforce the homeostasis of quiescent hematopoietic stem cells by repressing Socs3 expression.
Volume: 214
Issue: 7
Pages: 1901-1912
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24820309 | J:211277
First Author: Duek A
Year: 2014
Journal: Blood
Title: Loss of Stat1 decreases megakaryopoiesis and favors erythropoiesis in a JAK2-V617F-driven mouse model of MPNs.
Volume: 123
Issue: 25
Pages: 3943-50
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27133820 | J:237878
First Author: Zhan H
Year: 2016
Journal: Leukemia
Title: JAK2V617F-mutant megakaryocytes contribute to hematopoietic stem/progenitor cell expansion in a model of murine myeloproliferation.
Volume: 30
Issue: 12
Pages: 2332-2341
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16905102 | J:201263
First Author: Bergamin E
Year: 2006
Journal: Structure
Title: Structural basis for phosphotyrosine recognition by suppressor of cytokine signaling-3.
Volume: 14
Issue: 8
Pages: 1285-92
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16098827 | J:129837
First Author: Ren D
Year: 2005
Journal: Cell Metab
Title: Identification of SH2-B as a key regulator of leptin sensitivity, energy balance, and body weight in mice.
Volume: 2
Issue: 2
Pages: 95-104
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28912580 | J:255767
First Author: Shintani T
Year: 2017
Journal: Sci Rep
Title: PTPRJ Inhibits Leptin Signaling, and Induction of PTPRJ in the Hypothalamus Is a Cause of the Development of Leptin Resistance.
Volume: 7
Issue: 1
Pages: 11627
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25194569 | J:227594
First Author: Price FD
Year: 2014
Journal: Nat Med
Title: Inhibition of JAK-STAT signaling stimulates adult satellite cell function.
Volume: 20
Issue: 10
Pages: 1174-81
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16966486 | J:114638
First Author: Samardzija M
Year: 2006
Journal: FASEB J
Title: Differential role of Jak-STAT signaling in retinal degenerations.
Volume: 20
Issue: 13
Pages: 2411-3
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29168692 | J:254972
   
First Author: Klisch TJ
Year: 2017
Journal: Elife
Title: Jak2-mediated phosphorylation of Atoh1 is critical for medulloblastoma growth.
Volume: 6
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32160545 | J:288284
First Author: Viaud M
Year: 2020
Journal: Cell Rep
Title: ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms.
Volume: 30
Issue: 10
Pages: 3397-3410.e5
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30254368 | J:268393
First Author: Balcerek J
Year: 2018
Journal: Nat Commun
Title: Lnk/Sh2b3 deficiency restores hematopoietic stem cell function and genome integrity in Fancd2 deficient Fanconi anemia.
Volume: 9
Issue: 1
Pages: 3915
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34433042 | J:350601
First Author: Qian Y
Year: 2021
Journal: Cell Rep
Title: ZEB1 promotes pathogenic Th1 and Th17 cell differentiation in multiple sclerosis.
Volume: 36
Issue: 8
Pages: 109602
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35459909 | J:330712
First Author: Das Gupta D
Year: 2022
Journal: Cell Death Differ
Title: IRF4 deficiency vulnerates B-cell progeny for leukemogenesis via somatically acquired Jak3 mutations conferring IL-7 hypersensitivity.
Volume: 29
Issue: 11
Pages: 2163-2176
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22941110 | J:204885
First Author: Huang H
Year: 2012
Journal: Nat Neurosci
Title: Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling.
Volume: 15
Issue: 10
Pages: 1391-8
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16287972 | J:103836
First Author: Kimura A
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Suppressor of cytokine signaling-1 selectively inhibits LPS-induced IL-6 production by regulating JAK-STAT.
Volume: 102
Issue: 47
Pages: 17089-94
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31085626 | J:276872
 
First Author: Li XG
Year: 2019
Journal: EMBO Rep
Title: Tau accumulation triggers STAT1-dependent memory deficits by suppressing NMDA receptor expression.
Volume: 20
Issue: 6
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24475281 | J:212706
First Author: Hawkins ED
Year: 2014
Journal: PLoS One
Title: Lethal giant larvae 1 tumour suppressor activity is not conserved in models of mammalian T and B cell leukaemia.
Volume: 9
Issue: 1
Pages: e87376
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34707127 | J:313672
First Author: Wang J
Year: 2021
Journal: Nat Commun
Title: Optineurin modulates the maturation of dendritic cells to regulate autoimmunity through JAK2-STAT3 signaling.
Volume: 12
Issue: 1
Pages: 6198
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32213656 | J:303277
First Author: Aikawa S
Year: 2020
Journal: Reproduction
Title: Scribble promotes alveologenesis in the pregnant mammary gland for milk production.
Volume: 159
Issue: 6
Pages: 719-731
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36172386 | J:336030
 
First Author: Loh JT
Year: 2022
Journal: Front Immunol
Title: Dok3 restrains neutrophil production of calprotectin during TLR4 sensing of SARS-CoV-2 spike protein.
Volume: 13
Pages: 996637
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9753648 | J:50047
First Author: Piekorz R
Year: 1998
Journal: Biochem Biophys Res Commun
Title: Reconstitution of IL6-inducible differentiation of a myeloid leukemia cell line by activated Stat factors.
Volume: 250
Issue: 2
Pages: 436-43
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16365452 | J:126611
First Author: Han SH
Year: 2006
Journal: J Immunol
Title: Lipoteichoic acid-induced nitric oxide production depends on the activation of platelet-activating factor receptor and Jak2.
Volume: 176
Issue: 1
Pages: 573-9
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18228120 | J:134077
First Author: Wagner KU
Year: 2008
Journal: J Mammary Gland Biol Neoplasia
Title: Jak2/Stat5 signaling in mammogenesis, breast cancer initiation and progression.
Volume: 13
Issue: 1
Pages: 93-103
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19103304 | J:147203
First Author: Akasaka Y
Year: 2009
Journal: Biochim Biophys Acta
Title: Chronic leptin treatment stimulates lipid oxidation in immortalized and primary mouse skeletal muscle cells.
Volume: 1791
Issue: 2
Pages: 103-9
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21263445 | J:171008
First Author: Landrette SF
Year: 2011
Journal: Leukemia
Title: The transcription factor PlagL2 activates Mpl transcription and signaling in hematopoietic progenitor and leukemia cells.
Volume: 25
Issue: 4
Pages: 655-62
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22284190 | J:182300
First Author: Nicolas CS
Year: 2012
Journal: Neuron
Title: The Jak/STAT pathway is involved in synaptic plasticity.
Volume: 73
Issue: 2
Pages: 374-90
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23047478 | J:196798
First Author: Tijchon E
Year: 2013
Journal: Leukemia
Title: B-lineage transcription factors and cooperating gene lesions required for leukemia development.
Volume: 27
Issue: 3
Pages: 541-52
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27285583 | J:234838
First Author: Lee P
Year: 2016
Journal: Leukemia
Title: The biology, pathogenesis and clinical aspects of acute lymphoblastic leukemia in children with Down syndrome.
Volume: 30
Issue: 9
Pages: 1816-23
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30944096 | J:277215
 
First Author: Wang X
Year: 2019
Journal: EMBO J
Title: OTUB1 inhibits CNS autoimmunity by preventing IFN-γ-induced hyperactivation of astrocytes.
Volume: 38
Issue: 10
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32213463 | J:306920
First Author: Ge X
Year: 2020
Journal: iScience
Title: Renin Promotes STAT4 Phosphorylation to Induce IL-17 Production in Keratinocytes of Oral Lichen Planus.
Volume: 23
Issue: 4
Pages: 100983
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Publication
34678207 | J:331244
First Author: Muggeo S
Year: 2021
Journal: Stem Cell Reports
Title: PBX1-directed stem cell transcriptional program drives tumor progression in myeloproliferative neoplasm.
Volume: 16
Issue: 11
Pages: 2607-2616
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35294228 | J:322875
First Author: Lee Y
Year: 2022
Journal: Sci Adv
Title: Hematopoietic stem cells temporally transition to thrombopoietin dependence in the fetal liver.
Volume: 8
Issue: 11
Pages: eabm7688
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35198891 | J:343968
First Author: Wang R
Year: 2022
Journal: iScience
Title: Abi1 mediates airway smooth muscle cell proliferation and airway remodeling via Jak2/STAT3 signaling.
Volume: 25
Issue: 2
Pages: 103833
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Publication
36396719 | J:338366
First Author: Cao HJ
Year: 2023
Journal: Cell Death Differ
Title: ARID2 mitigates hepatic steatosis via promoting the ubiquitination of JAK2.
Volume: 30
Issue: 2
Pages: 383-396
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Publication
30005133 | J:268532
First Author: Zhang Y
Year: 2018
Journal: Stem Cells
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