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Search results 401 to 500 out of 801 for Lgr5

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Category: Publication
Type Details Score
Publication
First Author: Cedeno RJ
Year: 2017
Journal: PLoS One
Title: The histone variant macroH2A confers functional robustness to the intestinal stem cell compartment.
Volume: 12
Issue: 9
Pages: e0185196
Publication
First Author: Meinicke H
Year: 2017
Journal: Immunology
Title: Tumour-associated changes in intestinal epithelial cells cause local accumulation of KLRG1+ GATA3+ regulatory T cells in mice.
Volume: 152
Issue: 1
Pages: 74-88
Publication
First Author: Li L
Year: 2020
Journal: Int J Cancer
Title: UHRF2 promotes intestinal tumorigenesis through stabilization of TCF4 mediated Wnt/β-catenin signaling.
Volume: 147
Issue: 8
Pages: 2239-2252
Publication
First Author: Liu M
Year: 2017
Journal: Stem Cell Reports
Title: RHOA GTPase Controls YAP-Mediated EREG Signaling in Small Intestinal Stem Cell Maintenance.
Volume: 9
Issue: 6
Pages: 1961-1975
Publication
First Author: Fu DJ
Year: 2020
Journal: Nat Commun
Title: Gastric squamous-columnar junction contains a large pool of cancer-prone immature osteopontin responsive Lgr5-CD44+ cells.
Volume: 11
Issue: 1
Pages: 84
Publication
First Author: Yilmaz ÖH
Year: 2012
Journal: Nature
Title: mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake.
Volume: 486
Issue: 7404
Pages: 490-5
Publication
First Author: Feng L
Year: 2016
Journal: J Cell Sci
Title: ADAM10-Notch signaling governs the recruitment of ovarian pregranulosa cells and controls folliculogenesis in mice.
Volume: 129
Issue: 11
Pages: 2202-12
Publication
First Author: Horvay K
Year: 2015
Journal: EMBO J
Title: Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium.
Volume: 34
Issue: 10
Pages: 1319-35
Publication
First Author: Xia M
Year: 2023
Journal: Sci Adv
Title: Varying mechanical forces drive sensory epithelium formation.
Volume: 9
Issue: 44
Pages: eadf2664
Publication
First Author: Leung AOW
Year: 2024
Journal: Nat Commun
Title: Suppression of apoptosis impairs phalangeal joint formation in the pathogenesis of brachydactyly type A1.
Volume: 15
Issue: 1
Pages: 2229
Publication
First Author: Choi W
Year: 2018
Journal: Cancer Res
Title: YAP/TAZ Initiates Gastric Tumorigenesis via Upregulation of MYC.
Volume: 78
Issue: 12
Pages: 3306-3320
Publication
First Author: May S
Year: 2018
Journal: J Pathol
Title: Mbd2 enables tumourigenesis within the intestine while preventing tumour-promoting inflammation.
Volume: 245
Issue: 3
Pages: 270-282
Publication
First Author: de Sousa e Melo F
Year: 2017
Journal: Nature
Title: A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer.
Volume: 543
Issue: 7647
Pages: 676-680
Publication
First Author: Ishibashi F
Year: 2018
Journal: Stem Cell Reports
Title: Contribution of ATOH1+ Cells to the Homeostasis, Repair, and Tumorigenesis of the Colonic Epithelium.
Volume: 10
Issue: 1
Pages: 27-42
Publication  
First Author: Hu S
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: cGAS restricts colon cancer development by protecting intestinal barrier integrity.
Volume: 118
Issue: 23
Publication
First Author: Horazna M
Year: 2019
Journal: Sci Rep
Title: Msx1 loss suppresses formation of the ectopic crypts developed in the Apc-deficient small intestinal epithelium.
Volume: 9
Issue: 1
Pages: 1629
Publication
First Author: Ladang A
Year: 2015
Journal: J Exp Med
Title: Elp3 drives Wnt-dependent tumor initiation and regeneration in the intestine.
Volume: 212
Issue: 12
Pages: 2057-75
Publication
First Author: Tabrizian T
Year: 2017
Journal: Endocr Relat Cancer
Title: Apc inactivation, but not obesity, synergizes with Pten deficiency to drive intestinal stem cell-derived tumorigenesis.
Volume: 24
Issue: 6
Pages: 253-265
Publication
First Author: Högström J
Year: 2018
Journal: Cancer Res
Title: Transcription Factor PROX1 Suppresses Notch Pathway Activation via the Nucleosome Remodeling and Deacetylase Complex in Colorectal Cancer Stem-like Cells.
Volume: 78
Issue: 20
Pages: 5820-5832
Publication      
First Author: Llado V
Year: 2015
Journal: Cell Rep
Title: Repression of Intestinal Stem Cell Function and Tumorigenesis through Direct Phosphorylation of β-Catenin and Yap by PKCζ
Publication
First Author: Shelton PM
Year: 2018
Journal: Cell Rep
Title: The Secretion of miR-200s by a PKCζ/ADAR2 Signaling Axis Promotes Liver Metastasis in Colorectal Cancer.
Volume: 23
Issue: 4
Pages: 1178-1191
Publication
First Author: Goncalves MD
Year: 2019
Journal: Science
Title: High-fructose corn syrup enhances intestinal tumor growth in mice.
Volume: 363
Issue: 6433
Pages: 1345-1349
Publication
First Author: Kretzschmar K
Year: 2016
Journal: Cell Rep
Title: Compartmentalized Epidermal Activation of β-Catenin Differentially Affects Lineage Reprogramming and Underlies Tumor Heterogeneity.
Volume: 14
Issue: 2
Pages: 269-81
Publication
First Author: Lo YH
Year: 2017
Journal: Gastroenterology
Title: SPDEF Induces Quiescence of Colorectal Cancer Cells by Changing the Transcriptional Targets of β-catenin.
Volume: 153
Issue: 1
Pages: 205-218.e8
Publication
First Author: Pastushenko I
Year: 2021
Journal: Nature
Title: Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis.
Volume: 589
Issue: 7842
Pages: 448-455
Publication
First Author: Stine RR
Year: 2019
Journal: Cell Stem Cell
Title: PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism.
Volume: 25
Issue: 6
Pages: 830-845.e8
Publication
First Author: Lowry WE
Year: 2016
Journal: J Invest Dermatol
Title: Exploiting Mouse Models to Study Ras-Induced Cutaneous Squamous Cell Carcinoma.
Volume: 136
Issue: 8
Pages: 1543-8
Publication
First Author: Valenta T
Year: 2016
Journal: Cell Rep
Title: Wnt Ligands Secreted by Subepithelial Mesenchymal Cells Are Essential for the Survival of Intestinal Stem Cells and Gut Homeostasis.
Volume: 15
Issue: 5
Pages: 911-918
Publication
First Author: Kuzmichev AN
Year: 2012
Journal: Curr Biol
Title: Sox2 acts through Sox21 to regulate transcription in pluripotent and differentiated cells.
Volume: 22
Issue: 18
Pages: 1705-10
Publication
First Author: Wang L
Year: 2021
Journal: FASEB J
Title: SHP2 regulates the development of intestinal epithelium by modifying OSTERIX+ crypt stem cell self-renewal and proliferation.
Volume: 35
Issue: 1
Pages: e21106
Publication
First Author: Dmitrieva-Posocco O
Year: 2022
Journal: Nature
Title: β-Hydroxybutyrate suppresses colorectal cancer.
Volume: 605
Issue: 7908
Pages: 160-165
Publication
First Author: López I
Year: 2020
Journal: Oncogene
Title: An unanticipated tumor-suppressive role of the SUMO pathway in the intestine unveiled by Ubc9 haploinsufficiency.
Volume: 39
Issue: 43
Pages: 6692-6703
Publication
First Author: Zhao B
Year: 2019
Journal: Nat Commun
Title: Znhit1 controls intestinal stem cell maintenance by regulating H2A.Z incorporation.
Volume: 10
Issue: 1
Pages: 1071
Publication  
First Author: Zwiggelaar RT
Year: 2020
Journal: Sci Adv
Title: LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium.
Volume: 6
Issue: 37
Publication
First Author: Yang X
Year: 2024
Journal: Proc Natl Acad Sci U S A
Title: Excessive nucleic acid R-loops induce mitochondria-dependent epithelial cell necroptosis and drive spontaneous intestinal inflammation.
Volume: 121
Issue: 1
Pages: e2307395120
Publication
First Author: Ye P
Year: 2018
Journal: PLoS Genet
Title: Tankyrases maintain homeostasis of intestinal epithelium by preventing cell death.
Volume: 14
Issue: 9
Pages: e1007697
Publication
First Author: Jadhav U
Year: 2017
Journal: Cell Stem Cell
Title: Dynamic Reorganization of Chromatin Accessibility Signatures during Dedifferentiation of Secretory Precursors into Lgr5+ Intestinal Stem Cells.
Volume: 21
Issue: 1
Pages: 65-77.e5
Publication
First Author: Vázquez-Arreguín K
Year: 2019
Journal: PLoS Genet
Title: Oct1/Pou2f1 is selectively required for colon regeneration and regulates colon malignancy.
Volume: 15
Issue: 5
Pages: e1007687
Publication
First Author: Zhang S
Year: 2020
Journal: Cell Mol Life Sci
Title: Knockdown of Foxg1 in supporting cells increases the trans-differentiation of supporting cells into hair cells in the neonatal mouse cochlea.
Volume: 77
Issue: 7
Pages: 1401-1419
Publication
First Author: Li N
Year: 2016
Journal: Dev Dyn
Title: Heterogeneity in readouts of canonical wnt pathway activity within intestinal crypts.
Volume: 245
Issue: 8
Pages: 822-33
Publication  
First Author: Švec J
Year: 2022
Journal: Cancers (Basel)
Title: TROP2 Represents a Negative Prognostic Factor in Colorectal Adenocarcinoma and Its Expression Is Associated with Features of Epithelial-Mesenchymal Transition and Invasiveness.
Volume: 14
Issue: 17
Publication
First Author: Hiramatsu Y
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Arid1a is essential for intestinal stem cells through Sox9 regulation.
Volume: 116
Issue: 5
Pages: 1704-1713
Publication
First Author: Kunze B
Year: 2021
Journal: Sci Rep
Title: Notch signaling drives development of Barrett's metaplasia from Dclk1-positive epithelial tuft cells in the murine gastric mucosa.
Volume: 11
Issue: 1
Pages: 4509
Publication
First Author: Igarashi M
Year: 2016
Journal: Cell
Title: mTORC1 and SIRT1 Cooperate to Foster Expansion of Gut Adult Stem Cells during Calorie Restriction.
Volume: 166
Issue: 2
Pages: 436-450
Publication
First Author: Eshleman EM
Year: 2024
Journal: Immunity
Title: Microbiota-derived butyrate restricts tuft cell differentiation via histone deacetylase 3 to modulate intestinal type 2 immunity.
Volume: 57
Issue: 2
Pages: 319-332.e6
Publication
First Author: Zou WY
Year: 2018
Journal: Cell Rep
Title: Epithelial WNT Ligands Are Essential Drivers of Intestinal Stem Cell Activation.
Volume: 22
Issue: 4
Pages: 1003-1015
Publication
First Author: Kim TH
Year: 2014
Journal: Nature
Title: Broadly permissive intestinal chromatin underlies lateral inhibition and cell plasticity.
Volume: 506
Issue: 7489
Pages: 511-5
Publication
First Author: Niec RE
Year: 2022
Journal: Cell Stem Cell
Title: Lymphatics act as a signaling hub to regulate intestinal stem cell activity.
Volume: 29
Issue: 7
Pages: 1067-1082.e18
Publication
First Author: Jardé T
Year: 2020
Journal: Cell Stem Cell
Title: Mesenchymal Niche-Derived Neuregulin-1 Drives Intestinal Stem Cell Proliferation and Regeneration of Damaged Epithelium.
Volume: 27
Issue: 4
Pages: 646-662.e7
Publication
First Author: Cox BC
Year: 2014
Journal: Development
Title: Spontaneous hair cell regeneration in the neonatal mouse cochlea in vivo.
Volume: 141
Issue: 4
Pages: 816-29
Publication
First Author: Wang Y
Year: 2019
Journal: Cell
Title: Long-Term Culture Captures Injury-Repair Cycles of Colonic Stem Cells.
Volume: 179
Issue: 5
Pages: 1144-1159.e15
Publication
First Author: Yoshioka T
Year: 2019
Journal: J Pathol
Title: Bmi1 marks gastric stem cells located in the isthmus in mice.
Volume: 248
Issue: 2
Pages: 179-190
Publication
First Author: Hsu YC
Year: 2011
Journal: Cell
Title: Dynamics between stem cells, niche, and progeny in the hair follicle.
Volume: 144
Issue: 1
Pages: 92-105
Publication
First Author: Agudo J
Year: 2018
Journal: Immunity
Title: Quiescent Tissue Stem Cells Evade Immune Surveillance.
Volume: 48
Issue: 2
Pages: 271-285.e5
Publication
First Author: Cordero-Espinoza L
Year: 2021
Journal: Cell Stem Cell
Title: Dynamic cell contacts between periportal mesenchyme and ductal epithelium act as a rheostat for liver cell proliferation.
Volume: 28
Issue: 11
Pages: 1907-1921.e8
Publication
First Author: Wei X
Year: 2022
Journal: Cell Rep
Title: Ablating Lgr5-expressing prostatic stromal cells activates the ERK-mediated mechanosensory signaling and disrupts prostate tissue homeostasis.
Volume: 40
Issue: 10
Pages: 111313
Publication  
First Author: Sanz-Navarro M
Year: 2018
Journal: Development
Title: Plasticity within the niche ensures the maintenance of a Sox2+ stem cell population in the mouse incisor.
Volume: 145
Issue: 1
Publication
First Author: Säisä-Borreill S
Year: 2023
Journal: Cell Death Differ
Title: General transcription factor TAF4 antagonizes epigenetic silencing by Polycomb to maintain intestine stem cell functions.
Volume: 30
Issue: 3
Pages: 839-853
Publication
First Author: Goto N
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Lineage tracing and targeting of IL17RB+ tuft cell-like human colorectal cancer stem cells.
Volume: 116
Issue: 26
Pages: 12996-13005
Publication
First Author: He D
Year: 2020
Journal: Nat Commun
Title: Gut stem cell aging is driven by mTORC1 via a p38 MAPK-p53 pathway.
Volume: 11
Issue: 1
Pages: 37
Publication
First Author: Stringer EJ
Year: 2012
Journal: Development
Title: Cdx2 determines the fate of postnatal intestinal endoderm.
Volume: 139
Issue: 3
Pages: 465-74
Publication
First Author: Chiacchiera F
Year: 2016
Journal: Cell Stem Cell
Title: Polycomb Complex PRC1 Preserves Intestinal Stem Cell Identity by Sustaining Wnt/β-Catenin Transcriptional Activity.
Volume: 18
Issue: 1
Pages: 91-103
Publication  
First Author: Ghobashi AH
Year: 2024
Journal: Cancers (Basel)
Title: Single-Cell Profiling Reveals the Impact of Genetic Alterations on the Differentiation of Inflammation-Induced Murine Colon Tumors.
Volume: 16
Issue: 11
Publication
First Author: Tong K
Year: 2017
Journal: Cell Rep
Title: Degree of Tissue Differentiation Dictates Susceptibility to BRAF-Driven Colorectal Cancer.
Volume: 21
Issue: 13
Pages: 3833-3845
Publication
First Author: Boumahdi S
Year: 2014
Journal: Nature
Title: SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma.
Volume: 511
Issue: 7508
Pages: 246-50
Publication
First Author: Adam RC
Year: 2018
Journal: Cell Stem Cell
Title: Temporal Layering of Signaling Effectors Drives Chromatin Remodeling during Hair Follicle Stem Cell Lineage Progression.
Volume: 22
Issue: 3
Pages: 398-413.e7
Publication
First Author: Pant V
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Transient enhancement of p53 activity protects from radiation-induced gastrointestinal toxicity.
Volume: 116
Issue: 35
Pages: 17429-17437
Publication
First Author: Tang Y
Year: 2019
Journal: Int J Biol Sci
Title: E-cadherin is Required for the Homeostasis of Lgr5+ Gastric Antral Stem Cells.
Volume: 15
Issue: 1
Pages: 34-43
Publication
First Author: Yousefi M
Year: 2018
Journal: Stem Cell Reports
Title: Calorie Restriction Governs Intestinal Epithelial Regeneration through Cell-Autonomous Regulation of mTORC1 in Reserve Stem Cells.
Volume: 10
Issue: 3
Pages: 703-711
Publication  
First Author: Brischetto C
Year: 2021
Journal: Development
Title: NF-κB determines Paneth versus goblet cell fate decision in the small intestine.
Volume: 148
Issue: 21
Publication
First Author: Gregorieff A
Year: 2015
Journal: Nature
Title: Yap-dependent reprogramming of Lgr5(+) stem cells drives intestinal regeneration and cancer.
Volume: 526
Issue: 7575
Pages: 715-8
Publication
First Author: Vermeulen L
Year: 2013
Journal: Science
Title: Defining stem cell dynamics in models of intestinal tumor initiation.
Volume: 342
Issue: 6161
Pages: 995-8
Publication
First Author: Mahapatro M
Year: 2016
Journal: Cell Rep
Title: Programming of Intestinal Epithelial Differentiation by IL-33 Derived from Pericryptal Fibroblasts in Response to Systemic Infection.
Volume: 15
Issue: 8
Pages: 1743-56
Publication  
First Author: Wang S
Year: 2015
Journal: Nat Commun
Title: Transformation of the intestinal epithelium by the MSI2 RNA-binding protein.
Volume: 6
Pages: 6517
Publication
First Author: Wilson CH
Year: 2012
Journal: EMBO J
Title: Nuclear receptor binding protein 1 regulates intestinal progenitor cell homeostasis and tumour formation.
Volume: 31
Issue: 11
Pages: 2486-97
Publication
First Author: Cuitiño MC
Year: 2019
Journal: Cell Rep
Title: Two Distinct E2F Transcriptional Modules Drive Cell Cycles and Differentiation.
Volume: 27
Issue: 12
Pages: 3547-3560.e5
Publication
First Author: Fernandez Vallone V
Year: 2016
Journal: Development
Title: Trop2 marks transient gastric fetal epithelium and adult regenerating cells after epithelial damage.
Volume: 143
Issue: 9
Pages: 1452-63
Publication  
First Author: Jin YR
Year: 2020
Journal: Front Cell Dev Biol
Title: Canonical WNT/β-Catenin Signaling Activated by WNT9b and RSPO2 Cooperation Regulates Facial Morphogenesis in Mice.
Volume: 8
Pages: 264
Publication
First Author: Fu NY
Year: 2018
Journal: Dev Cell
Title: Foxp1 Is Indispensable for Ductal Morphogenesis and Controls the Exit of Mammary Stem Cells from Quiescence.
Volume: 47
Issue: 5
Pages: 629-644.e8
Publication
First Author: Mu Q
Year: 2025
Journal: Dev Cell
Title: FZD5 controls intestinal crypt homeostasis and colonic Wnt surrogate agonist response.
Volume: 60
Issue: 3
Pages: 342-351.e5
Publication    
First Author: Tian Y
Year: 2017
Journal: Elife
Title: Stress responsive miR-31 is a major modulator of mouse intestinal stem cells during regeneration and tumorigenesis.
Volume: 6
Publication
First Author: Tetteh PW
Year: 2016
Journal: Cell Stem Cell
Title: Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters.
Volume: 18
Issue: 2
Pages: 203-13
Publication
First Author: Qin Y
Year: 2018
Journal: PLoS Genet
Title: Gli3 is a negative regulator of Tas1r3-expressing taste cells.
Volume: 14
Issue: 2
Pages: e1007058
Publication
First Author: Fischer JM
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Single cell lineage tracing reveals a role for TgfβR2 in intestinal stem cell dynamics and differentiation.
Volume: 113
Issue: 43
Pages: 12192-12197
Publication
First Author: Parham LR
Year: 2024
Journal: Cell Mol Gastroenterol Hepatol
Title: IGF2BP1/IMP1 Deletion Enhances a Facultative Stem Cell State via Regulation of MAP1LC3B.
Volume: 17
Issue: 3
Pages: 439-451
Publication
First Author: Han H
Year: 2020
Journal: EMBO J
Title: Loss of aryl hydrocarbon receptor potentiates FoxM1 signaling to enhance self-renewal of colonic stem and progenitor cells.
Volume: 39
Issue: 19
Pages: e104319
Publication
First Author: Barry ER
Year: 2013
Journal: Nature
Title: Restriction of intestinal stem cell expansion and the regenerative response by YAP.
Volume: 493
Issue: 7430
Pages: 106-10
Publication
First Author: Böttcher A
Year: 2021
Journal: Nat Cell Biol
Title: Non-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates.
Volume: 23
Issue: 1
Pages: 23-31
Publication
First Author: Ohara TE
Year: 2022
Journal: Dev Cell
Title: Adaptive differentiation promotes intestinal villus recovery.
Volume: 57
Issue: 2
Pages: 166-179.e6
Publication
First Author: Lemmetyinen TT
Year: 2024
Journal: iScience
Title: Mesenchymal GDNF promotes intestinal enterochromaffin cell differentiation.
Volume: 27
Issue: 12
Pages: 111246
Publication
First Author: Goto N
Year: 2022
Journal: Cell Stem Cell
Title: Lymphatics and fibroblasts support intestinal stem cells in homeostasis and injury.
Volume: 29
Issue: 8
Pages: 1246-1261.e6
Publication
First Author: Morral C
Year: 2024
Journal: Nat Commun
Title: p53 promotes revival stem cells in the regenerating intestine after severe radiation injury.
Volume: 15
Issue: 1
Pages: 3018
Publication
First Author: Maurizy C
Year: 2021
Journal: Nat Commun
Title: The HSP90/R2TP assembly chaperone promotes cell proliferation in the intestinal epithelium.
Volume: 12
Issue: 1
Pages: 4810
Publication
First Author: Mohapatra B
Year: 2017
Journal: Development
Title: An essential role of CBL and CBL-B ubiquitin ligases in mammary stem cell maintenance.
Volume: 144
Issue: 6
Pages: 1072-1086
Publication
First Author: Levy A
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Innate immune receptor NOD2 mediates LGR5+ intestinal stem cell protection against ROS cytotoxicity via mitophagy stimulation.
Volume: 117
Issue: 4
Pages: 1994-2003
Publication  
First Author: Cerretelli G
Year: 2023
Journal: Dis Model Mech
Title: Acetaldehyde and defective mismatch repair increase colonic tumours in a Lynch syndrome model with Aldh1b1 inactivation.
Volume: 16
Issue: 8
Publication    
First Author: McKinley KL
Year: 2018
Journal: Elife
Title: Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia.
Volume: 7
Publication
First Author: Niu W
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Two distinct pathways of pregranulosa cell differentiation support follicle formation in the mouse ovary.
Volume: 117
Issue: 33
Pages: 20015-20026
Publication
First Author: Nigmatullina L
Year: 2017
Journal: EMBO J
Title: Id2 controls specification of Lgr5+ intestinal stem cell progenitors during gut development.
Volume: 36
Issue: 7
Pages: 869-885
Publication
First Author: Taniguchi CM
Year: 2014
Journal: Sci Transl Med
Title: PHD inhibition mitigates and protects against radiation-induced gastrointestinal toxicity via HIF2.
Volume: 6
Issue: 236
Pages: 236ra64