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Search results 401 to 500 out of 557 for Tsc1

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Category: Publication
Type Details Score
Publication
First Author: Xu L
Year: 2017
Journal: Immunity
Title: The Kinase mTORC1 Promotes the Generation and Suppressive Function of Follicular Regulatory T Cells.
Volume: 47
Issue: 3
Pages: 538-551.e5
Publication
First Author: Su W
Year: 2020
Journal: Cell Metab
Title: Protein Prenylation Drives Discrete Signaling Programs for the Differentiation and Maintenance of Effector Treg Cells.
Volume: 32
Issue: 6
Pages: 996-1011.e7
Publication
First Author: Ersching J
Year: 2017
Journal: Immunity
Title: Germinal Center Selection and Affinity Maturation Require Dynamic Regulation of mTORC1 Kinase.
Volume: 46
Issue: 6
Pages: 1045-1058.e6
Publication  
First Author: Saygili Demir C
Year: 2023
Journal: J Cell Biol
Title: Mechanosensitive mTORC1 signaling maintains lymphatic valves.
Volume: 222
Issue: 6
Publication
First Author: Takahashi T
Year: 2001
Journal: J Am Soc Nephrol
Title: Temporally compartmentalized expression of ephrin-B2 during renal glomerular development.
Volume: 12
Issue: 12
Pages: 2673-82
Publication
First Author: Katholnig K
Year: 2013
Journal: J Immunol
Title: p38α senses environmental stress to control innate immune responses via mechanistic target of rapamycin.
Volume: 190
Issue: 4
Pages: 1519-27
Publication  
First Author: Switon K
Year: 2017
Journal: Neuroscience
Title: Molecular neurobiology of mTOR.
Volume: 341
Pages: 112-153
Publication
First Author: Gan B
Year: 2006
Journal: J Cell Biol
Title: Role of FIP200 in cardiac and liver development and its regulation of TNFalpha and TSC-mTOR signaling pathways.
Volume: 175
Issue: 1
Pages: 121-33
Publication
First Author: Wang S
Year: 2013
Journal: Cell Stem Cell
Title: Transient activation of autophagy via Sox2-mediated suppression of mTOR is an important early step in reprogramming to pluripotency.
Volume: 13
Issue: 5
Pages: 617-25
Publication
First Author: Way SW
Year: 2009
Journal: Hum Mol Genet
Title: Loss of Tsc2 in radial glia models the brain pathology of tuberous sclerosis complex in the mouse.
Volume: 18
Issue: 7
Pages: 1252-65
Publication
First Author: Williams T
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: AMP-activated protein kinase (AMPK) activity is not required for neuronal development but regulates axogenesis during metabolic stress.
Volume: 108
Issue: 14
Pages: 5849-54
Publication
First Author: Harrington LS
Year: 2004
Journal: J Cell Biol
Title: The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins.
Volume: 166
Issue: 2
Pages: 213-23
Publication
First Author: Bhaskar PT
Year: 2009
Journal: Mol Cell Biol
Title: mTORC1 hyperactivity inhibits serum deprivation-induced apoptosis via increased hexokinase II and GLUT1 expression, sustained Mcl-1 expression, and glycogen synthase kinase 3beta inhibition.
Volume: 29
Issue: 18
Pages: 5136-47
Publication
First Author: de la Torre-Ubieta L
Year: 2016
Journal: Nat Med
Title: Advancing the understanding of autism disease mechanisms through genetics.
Volume: 22
Issue: 4
Pages: 345-61
Publication  
First Author: Li Q
Year: 2024
Journal: J Clin Invest
Title: Metabolic rewiring during bone development underlies tRNA m7G-associated primordial dwarfism.
Volume: 134
Issue: 20
Publication    
First Author: Garg A
Year: 2020
Journal: Elife
Title: Etv transcription factors functionally diverge from their upstream FGF signaling in lens development.
Volume: 9
Publication
First Author: Hossain Z
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1.
Volume: 104
Issue: 5
Pages: 1631-6
Publication
First Author: Zhou Z
Year: 2015
Journal: Dev Cell
Title: RNA Binding Protein Nanos2 Organizes Post-transcriptional Buffering System to Retain Primitive State of Mouse Spermatogonial Stem Cells.
Volume: 34
Issue: 1
Pages: 96-107
Publication
First Author: Li J
Year: 2017
Journal: Nat Neurosci
Title: Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
Volume: 20
Issue: 8
Pages: 1150-1161
Publication
First Author: Nie X
Year: 2020
Journal: Dev Biol
Title: mTOR plays a pivotal role in multiple processes of enamel organ development principally through the mTORC1 pathway and in part via regulating cytoskeleton dynamics.
Volume: 467
Issue: 1-2
Pages: 77-87
Publication  
First Author: Wang Q
Year: 2021
Journal: Sci Adv
Title: Lacrimal gland budding requires PI3K-dependent suppression of EGF signaling.
Volume: 7
Issue: 27
Publication    
First Author: Lim S
Year: 2021
Journal: Elife
Title: mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent Müller glia.
Volume: 10
Publication
First Author: Choi JH
Year: 2018
Journal: Nat Commun
Title: mTORC1 accelerates retinal development via the immunoproteasome.
Volume: 9
Issue: 1
Pages: 2502
Publication
First Author: Hughes CHK
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Steroidogenic factor 1 (SF-1; Nr5a1) regulates the formation of the ovarian reserve.
Volume: 120
Issue: 32
Pages: e2220849120
Publication
First Author: Distler U
Year: 2014
Journal: Proteomics
Title: In-depth protein profiling of the postsynaptic density from mouse hippocampus using data-independent acquisition proteomics.
Volume: 14
Issue: 21-22
Pages: 2607-13
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication  
First Author: Lai M
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Tsc1 regulates tight junction independent of mTORC1.
Volume: 118
Issue: 30
Publication
First Author: Wan M
Year: 2006
Journal: FEBS Lett
Title: Muscle atrophy in transgenic mice expressing a human TSC1 transgene.
Volume: 580
Issue: 24
Pages: 5621-7
Publication
First Author: Garami A
Year: 2003
Journal: Mol Cell
Title: Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2.
Volume: 11
Issue: 6
Pages: 1457-66
Publication
First Author: Wu R
Year: 2019
Journal: Cell Metab
Title: The Circadian Protein Period2 Suppresses mTORC1 Activity via Recruiting Tsc1 to mTORC1 Complex.
Volume: 29
Issue: 3
Pages: 653-667.e6
Publication
First Author: van Slegtenhorst M
Year: 1998
Journal: Hum Mol Genet
Title: Interaction between hamartin and tuberin, the TSC1 and TSC2 gene products.
Volume: 7
Issue: 6
Pages: 1053-7
Publication
First Author: Chong-Kopera H
Year: 2006
Journal: J Biol Chem
Title: TSC1 stabilizes TSC2 by inhibiting the interaction between TSC2 and the HERC1 ubiquitin ligase.
Volume: 281
Issue: 13
Pages: 8313-6
Publication
First Author: Muto E
Year: 2004
Journal: Biochimie
Title: Identification and characterization of Veph, a novel gene encoding a PH domain-containing protein expressed in the developing central nervous system of vertebrates.
Volume: 86
Issue: 8
Pages: 523-31
Publication
First Author: Shathasivam P
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Human ortholog of Drosophila Melted impedes SMAD2 release from TGF-β receptor I to inhibit TGF-β signaling.
Volume: 112
Issue: 23
Pages: E3000-9
Publication
First Author: Teleman AA
Year: 2005
Journal: Dev Cell
Title: Drosophila Melted modulates FOXO and TOR activity.
Volume: 9
Issue: 2
Pages: 271-81
Publication
First Author: Xu L
Year: 1995
Journal: Genomics
Title: Alternative splicing of the tuberous sclerosis 2 (TSC2) gene in human and mouse tissues.
Volume: 27
Issue: 3
Pages: 475-80
Publication
First Author: Li Y
Year: 2004
Journal: Mol Cell Biol
Title: Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity.
Volume: 24
Issue: 18
Pages: 7965-75
Publication
First Author: Tee AR
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling.
Volume: 99
Issue: 21
Pages: 13571-6
Publication
First Author: Cheadle JP
Year: 2000
Journal: Hum Genet
Title: Molecular genetic advances in tuberous sclerosis.
Volume: 107
Issue: 2
Pages: 97-114
Publication  
First Author: Chalkiadaki K
Year: 2023
Journal: Front Cell Dev Biol
Title: Reversal of memory and autism-related phenotypes in Tsc2(+/-) mice via inhibition of Nlgn1.
Volume: 11
Pages: 1205112
Publication
First Author: Nie D
Year: 2010
Journal: Nat Neurosci
Title: Tsc2-Rheb signaling regulates EphA-mediated axon guidance.
Volume: 13
Issue: 2
Pages: 163-72
Publication
First Author: Alesi N
Year: 2021
Journal: Nat Commun
Title: TSC2 regulates lysosome biogenesis via a non-canonical RAGC and TFEB-dependent mechanism.
Volume: 12
Issue: 1
Pages: 4245
Publication  
First Author: Sugiura H
Year: 2015
Journal: Nat Commun
Title: Rheb activation disrupts spine synapse formation through accumulation of syntenin in tuberous sclerosis complex.
Volume: 6
Pages: 6842
Publication
First Author: Lee MC
Year: 2023
Journal: Cell Rep
Title: A multiplexed in vivo approach to identify driver genes in small cell lung cancer.
Volume: 42
Issue: 1
Pages: 111990
Publication
First Author: Ko CJ
Year: 2021
Journal: EMBO J
Title: The E3 ubiquitin ligase Peli1 regulates the metabolic actions of mTORC1 to suppress antitumor T cell responses.
Volume: 40
Issue: 2
Pages: e104532
Publication
First Author: Hooshmandi M
Year: 2021
Journal: Cell Rep
Title: 4E-BP2-dependent translation in cerebellar Purkinje cells controls spatial memory but not autism-like behaviors.
Volume: 35
Issue: 4
Pages: 109036
Publication
First Author: Alesi N
Year: 2024
Journal: Nat Commun
Title: TFEB drives mTORC1 hyperactivation and kidney disease in Tuberous Sclerosis Complex.
Volume: 15
Issue: 1
Pages: 406
Publication
First Author: Riley VA
Year: 2023
Journal: iScience
Title: Tsc2 coordinates neuroprogenitor differentiation.
Volume: 26
Issue: 12
Pages: 108442
Publication
First Author: Jiang X
Year: 2024
Journal: Nat Commun
Title: Hypothalamic SLC7A14 accounts for aging-reduced lipolysis in white adipose tissue of male mice.
Volume: 15
Issue: 1
Pages: 7948
Publication
First Author: Scheidenhelm DK
Year: 2004
Journal: J Child Neurol
Title: Mouse models of tuberous sclerosis complex.
Volume: 19
Issue: 9
Pages: 726-33
Publication
First Author: Zhang HH
Year: 2006
Journal: Mol Cell
Title: S6K1 regulates GSK3 under conditions of mTOR-dependent feedback inhibition of Akt.
Volume: 24
Issue: 2
Pages: 185-97
Publication
First Author: Ma L
Year: 2005
Journal: Cell
Title: Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis.
Volume: 121
Issue: 2
Pages: 179-93
Publication
First Author: Zhang J
Year: 2013
Journal: Nat Cell Biol
Title: A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS.
Volume: 15
Issue: 10
Pages: 1186-96
Publication
First Author: Lee Y
Year: 2022
Journal: Sci Adv
Title: Hematopoietic stem cells temporally transition to thrombopoietin dependence in the fetal liver.
Volume: 8
Issue: 11
Pages: eabm7688
Publication
First Author: Xiao GH
Year: 1997
Journal: J Biol Chem
Title: The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis.
Volume: 272
Issue: 10
Pages: 6097-100
Publication
First Author: Sofer A
Year: 2005
Journal: Mol Cell Biol
Title: Regulation of mTOR and cell growth in response to energy stress by REDD1.
Volume: 25
Issue: 14
Pages: 5834-45
Publication
First Author: Li Z
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Ghrelin promotes hepatic lipogenesis by activation of mTOR-PPARγ signaling pathway.
Volume: 111
Issue: 36
Pages: 13163-8
Publication
First Author: Onda H
Year: 1999
Journal: J Clin Invest
Title: Tsc2(+/-) mice develop tumors in multiple sites that express gelsolin and are influenced by genetic background.
Volume: 104
Issue: 6
Pages: 687-95
Publication
First Author: Guo Y
Year: 2013
Journal: Mol Cancer Res
Title: Equivalent benefit of rapamycin and a potent mTOR ATP-competitive inhibitor, MLN0128 (INK128), in a mouse model of tuberous sclerosis.
Volume: 11
Issue: 5
Pages: 467-73
Publication
First Author: Mak BC
Year: 2005
Journal: Am J Pathol
Title: Aberrant beta-catenin signaling in tuberous sclerosis.
Volume: 167
Issue: 1
Pages: 107-16
Publication
First Author: Saré RM
Year: 2018
Journal: J Neurochem
Title: Decreased rates of cerebral protein synthesis measured in vivo in a mouse model of Tuberous Sclerosis Complex: unexpected consequences of reduced tuberin.
Volume: 145
Issue: 5
Pages: 417-425
Publication
First Author: Lee L
Year: 2005
Journal: Genes Chromosomes Cancer
Title: Efficacy of a rapamycin analog (CCI-779) and IFN-gamma in tuberous sclerosis mouse models.
Volume: 42
Issue: 3
Pages: 213-27
Publication
First Author: Cao J
Year: 2010
Journal: Hum Mol Genet
Title: Thoracic aortic disease in tuberous sclerosis complex: molecular pathogenesis and potential therapies in Tsc2+/- mice.
Volume: 19
Issue: 10
Pages: 1908-20
Publication  
First Author: Saré RM
Year: 2020
Journal: eNeuro
Title: Sex-Selective Effects on Behavior in a Mouse Model of Tuberous Sclerosis Complex.
Volume: 7
Issue: 2