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Search results 4001 to 4100 out of 5246 for App

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Category: Publication
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Type Details Score
Publication
16207713 | J:105902
First Author: Koldamova R
Year: 2005
Journal: J Biol Chem
Title: Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice.
Volume: 280
Issue: 52
Pages: 43224-35
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Publication
20881129 | J:164876
First Author: Lane RF
Year: 2010
Journal: J Neurosci
Title: Diabetes-associated SorCS1 regulates Alzheimer's amyloid-beta metabolism: evidence for involvement of SorL1 and the retromer complex.
Volume: 30
Issue: 39
Pages: 13110-5
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Publication
19176820 | J:144825
First Author: Rose JB
Year: 2009
Journal: J Neurosci
Title: Neuropeptide Y fragments derived from neprilysin processing are neuroprotective in a transgenic model of Alzheimer's disease.
Volume: 29
Issue: 4
Pages: 1115-25
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Publication
22044482 | J:182717
First Author: Hoshino T
Year: 2012
Journal: J Neurochem
Title: Improvement of cognitive function in Alzheimer's disease model mice by genetic and pharmacological inhibition of the EP(4) receptor.
Volume: 120
Issue: 5
Pages: 795-805
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Publication
23365231 | J:193889
First Author: Kaufmann MR
Year: 2013
Journal: J Neurosci
Title: Dysregulation of hypoxia-inducible factor by presenilin/γ-secretase loss-of-function mutations.
Volume: 33
Issue: 5
Pages: 1915-26
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Publication
34958873 | J:351594
 
First Author: Wang ZH
Year: 2022
Journal: Prog Neurobiol
Title: Neuronal ApoE4 stimulates C/EBPβ activation, promoting Alzheimer's disease pathology in a mouse model.
Volume: 209
Pages: 102212
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Publication
25728909 | J:224563
First Author: Vnencak M
Year: 2015
Journal: J Comp Neurol
Title: Deletion of the amyloid precursor-like protein 1 (APLP1) enhances excitatory synaptic transmission, reduces network inhibition but does not impair synaptic plasticity in the mouse dentate gyrus.
Volume: 523
Issue: 11
Pages: 1717-29
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Publication
30031059 | J:352676
 
First Author: Ren R
Year: 2018
Journal: Life Sci
Title: Specific deletion connexin43 in astrocyte ameliorates cognitive dysfunction in APP/PS1 mice.
Volume: 208
Pages: 175-191
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Publication
20371803 | J:159624
First Author: Jorissen E
Year: 2010
Journal: J Neurosci
Title: The disintegrin/metalloproteinase ADAM10 is essential for the establishment of the brain cortex.
Volume: 30
Issue: 14
Pages: 4833-44
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Publication
15229191 | J:92095
First Author: Mann KM
Year: 2004
Journal: Hum Mol Genet
Title: Independent effects of APOE on cholesterol metabolism and brain Abeta levels in an Alzheimer disease mouse model.
Volume: 13
Issue: 17
Pages: 1959-68
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Publication
19074039 | J:143045
First Author: Her LS
Year: 2008
Journal: J Neurosci
Title: Enhanced sensitivity of striatal neurons to axonal transport defects induced by mutant huntingtin.
Volume: 28
Issue: 50
Pages: 13662-72
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Publication
22184106 | J:182777
First Author: Ma SL
Year: 2012
Journal: J Biol Chem
Title: Prolyl isomerase Pin1 promotes amyloid precursor protein (APP) turnover by inhibiting glycogen synthase kinase-3β (GSK3β) activity: novel mechanism for Pin1 to protect against Alzheimer disease.
Volume: 287
Issue: 10
Pages: 6969-73
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Publication
34140411 | J:338510
 
First Author: Wu Z
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Neurotrophic signaling deficiency exacerbates environmental risks for Alzheimer's disease pathogenesis.
Volume: 118
Issue: 25
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Publication
14960573 | J:89471
First Author: Mackey SL
Year: 2004
Journal: J Biol Chem
Title: CCAAT enhancer-binding protein alpha is required for interleukin-6 receptor alpha signaling in newborn hepatocytes.
Volume: 279
Issue: 16
Pages: 16206-13
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Publication
30594669 | J:291320
 
First Author: Song HL
Year: 2019
Journal: Mol Cell Neurosci
Title: Ouabain activates transcription factor EB and exerts neuroprotection in models of Alzheimer's disease.
Volume: 95
Pages: 13-24
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Publication
22511594 | J:185280
First Author: Cossec JC
Year: 2012
Journal: Hum Mol Genet
Title: Trisomy for synaptojanin1 in Down syndrome is functionally linked to the enlargement of early endosomes.
Volume: 21
Issue: 14
Pages: 3156-72
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Publication
23926248 | J:199866
First Author: Prox J
Year: 2013
Journal: J Neurosci
Title: Postnatal disruption of the disintegrin/metalloproteinase ADAM10 in brain causes epileptic seizures, learning deficits, altered spine morphology, and defective synaptic functions.
Volume: 33
Issue: 32
Pages: 12915-28, 12928a
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Publication
38920631 | J:360321
 
First Author: Rombaut B
Year: 2024
Journal: Cells
Title: Early Inhibition of Phosphodiesterase 4B (PDE4B) Instills Cognitive Resilience in APPswe/PS1dE9 Mice.
Volume: 13
Issue: 12
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Publication
14701757 | J:285020
First Author: Christensen MA
Year: 2004
Journal: Mol Cell Biol
Title: Transcriptional regulation of BACE1, the beta-amyloid precursor protein beta-secretase, by Sp1.
Volume: 24
Issue: 2
Pages: 865-74
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Publication
29016862 | J:250498
First Author: Singh BK
Year: 2017
Journal: Hum Mol Genet
Title: Ube3a deficiency inhibits amyloid plaque formation in APPswe/PS1δE9 mouse model of Alzheimer's disease.
Volume: 26
Issue: 20
Pages: 4042-4054
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Publication
22114267 | J:178060
First Author: Mazzitelli S
Year: 2011
Journal: J Neurosci
Title: The loss of c-Jun N-terminal protein kinase activity prevents the amyloidogenic cleavage of amyloid precursor protein and the formation of amyloid plaques in vivo.
Volume: 31
Issue: 47
Pages: 16969-76
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Publication
23838176 | J:211719
First Author: Stumm C
Year: 2013
Journal: Neurobiol Aging
Title: Cannabinoid receptor 1 deficiency in a mouse model of Alzheimer's disease leads to enhanced cognitive impairment despite of a reduction in amyloid deposition.
Volume: 34
Issue: 11
Pages: 2574-84
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Publication
33149111 | J:355722
First Author: Mishra V
Year: 2020
Journal: Nat Commun
Title: Systematic elucidation of neuron-astrocyte interaction in models of amyotrophic lateral sclerosis using multi-modal integrated bioinformatics workflow.
Volume: 11
Issue: 1
Pages: 5579
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Publication
25316599 | J:329737
First Author: Joshi G
Year: 2015
Journal: Neurobiol Aging
Title: Increased Alzheimer's disease-like pathology in the APP/ PS1ΔE9 mouse model lacking Nrf2 through modulation of autophagy.
Volume: 36
Issue: 2
Pages: 664-79
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Publication
9278386 | J:42742
First Author: Itoh T
Year: 1997
Journal: J Biol Chem
Title: Unaltered secretion of beta-amyloid precursor protein in gelatinase A (matrix metalloproteinase 2)-deficient mice.
Volume: 272
Issue: 36
Pages: 22389-92
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Publication
20445063 | J:160557
First Author: Gimbel DA
Year: 2010
Journal: J Neurosci
Title: Memory impairment in transgenic Alzheimer mice requires cellular prion protein.
Volume: 30
Issue: 18
Pages: 6367-74
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Publication
20881126 | J:164877
First Author: Houeland G
Year: 2010
Journal: J Neurosci
Title: Transgenic mice with chronic NGF deprivation and Alzheimer's disease-like pathology display hippocampal region-specific impairments in short- and long-term plasticities.
Volume: 30
Issue: 39
Pages: 13089-94
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Publication
12388777 | J:79991
First Author: Rozmahel R
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Alleles at the Nicastrin locus modify presenilin 1- deficiency phenotype.
Volume: 99
Issue: 22
Pages: 14452-7
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Publication
21471357 | J:171188
First Author: Hoshino T
Year: 2011
Journal: J Neurosci
Title: Suppression of Alzheimer's disease-related phenotypes by expression of heat shock protein 70 in mice.
Volume: 31
Issue: 14
Pages: 5225-34
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Publication
23472157 | J:200200
First Author: He P
Year: 2013
Journal: PLoS One
Title: Chronic administration of anti-stroke herbal medicine TongLuoJiuNao reduces amyloidogenic processing of amyloid precursor protein in a mouse model of Alzheimer's disease.
Volume: 8
Issue: 3
Pages: e58181
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Publication
25194880 | J:218438
First Author: Wu Y
Year: 2015
Journal: Neurobiol Aging
Title: Amyloid-β precursor protein facilitates the regulator of calcineurin 1-mediated apoptosis by downregulating proteasome subunit α type-5 and proteasome subunit β type-7.
Volume: 36
Issue: 1
Pages: 169-77
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Publication
24269917 | J:259960
 
First Author: Koldamova R
Year: 2014
Journal: Neurobiol Dis
Title: Genome-wide approaches reveal EGR1-controlled regulatory networks associated with neurodegeneration.
Volume: 63
Pages: 107-14
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Publication
38216110 | J:360270
 
First Author: Xu M
Year: 2024
Journal: Exp Neurol
Title: PCSK6 exacerbates Alzheimer's disease pathogenesis by promoting MT5-MMP maturation.
Volume: 374
Pages: 114688
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Publication
34506227 | J:311362
First Author: Hendrickx JO
Year: 2021
Journal: Am J Physiol Heart Circ Physiol
Title: Altered stress hormone levels affect in vivo vascular function in the hAPP23+/- overexpressing mouse model of Alzheimer's disease.
Volume: 321
Issue: 5
Pages: H905-H919
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Publication
16274726 | J:129221
First Author: von Arnim CA
Year: 2006
Journal: Mech Ageing Dev
Title: Mechanisms of hypoxic tolerance in presymptomatic APP23 transgenic mice.
Volume: 127
Issue: 2
Pages: 109-14
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Publication
18077058 | J:152963
First Author: Priller C
Year: 2009
Journal: Neurobiol Aging
Title: Excitatory synaptic transmission is depressed in cultured hippocampal neurons of APP/PS1 mice.
Volume: 30
Issue: 8
Pages: 1227-37
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Publication
32061032 | J:285668
First Author: Du Y
Year: 2020
Journal: Aging Cell
Title: TRPV1 activation alleviates cognitive and synaptic plasticity impairments through inhibiting AMPAR endocytosis in APP23/PS45 mouse model of Alzheimer's disease.
Volume: 19
Issue: 3
Pages: e13113
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Publication
17767011 | J:127004
First Author: Hoshino T
Year: 2007
Journal: J Biol Chem
Title: Involvement of prostaglandin E2 in production of amyloid-beta peptides both in vitro and in vivo.
Volume: 282
Issue: 45
Pages: 32676-88
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Publication
17640880 | J:123302
First Author: Marutle A
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Modulation of human neural stem cell differentiation in Alzheimer (APP23) transgenic mice by phenserine.
Volume: 104
Issue: 30
Pages: 12506-11
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Publication
17121991 | J:118288
First Author: Sun X
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression.
Volume: 103
Issue: 49
Pages: 18727-32
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Publication
30176342 | J:270220
 
First Author: Zhang N
Year: 2018
Journal: Neurosci Lett
Title: The amyloid precursor protein binds to β-catenin and modulates its cellular distribution.
Volume: 685
Pages: 190-195
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Publication
16033885 | J:99847
First Author: Saura CA
Year: 2005
Journal: J Neurosci
Title: Conditional inactivation of presenilin 1 prevents amyloid accumulation and temporarily rescues contextual and spatial working memory impairments in amyloid precursor protein transgenic mice.
Volume: 25
Issue: 29
Pages: 6755-64
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Publication
23070049 | J:235255
First Author: Hartlage-Rübsamen M
Year: 2013
Journal: Int J Dev Neurosci
Title: Munc13 genotype regulates secretory amyloid precursor protein processing via postsynaptic glutamate receptors.
Volume: 31
Issue: 1
Pages: 36-45
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Publication
23223301 | J:193190
First Author: Kummer MP
Year: 2012
Journal: J Neurosci
Title: Mrp14 deficiency ameliorates amyloid β burden by increasing microglial phagocytosis and modulation of amyloid precursor protein processing.
Volume: 32
Issue: 49
Pages: 17824-9
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Publication
19118172 | J:142874
First Author: Ho A
Year: 2008
Journal: J Neurosci
Title: Deletion of Mint proteins decreases amyloid production in transgenic mouse models of Alzheimer's disease.
Volume: 28
Issue: 53
Pages: 14392-400
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Publication
29329433 | J:260790
First Author: Fang F
Year: 2018
Journal: Hum Mol Genet
Title: RAGE mediates Aβ accumulation in a mouse model of Alzheimer's disease via modulation of β- and γ-secretase activity.
Volume: 27
Issue: 6
Pages: 1002-1014
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Publication
20335454 | J:159221
First Author: Davis AA
Year: 2010
Journal: J Neurosci
Title: Deletion of M1 muscarinic acetylcholine receptors increases amyloid pathology in vitro and in vivo.
Volume: 30
Issue: 12
Pages: 4190-6
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Publication
22496554 | J:184454
First Author: Watanabe H
Year: 2012
Journal: J Neurosci
Title: Familial frontotemporal dementia-associated presenilin-1 c.548G>T mutation causes decreased mRNA expression and reduced presenilin function in knock-in mice.
Volume: 32
Issue: 15
Pages: 5085-96
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Publication
36688536 | J:350267
   
First Author: Rem PD
Year: 2023
Journal: Elife
Title: Soluble amyloid-β precursor peptide does not regulate GABA(B) receptor activity.
Volume: 12
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Publication
24599400 | J:211000
First Author: Xu YH
Year: 2014
Journal: Hum Mol Genet
Title: Multiple pathogenic proteins implicated in neuronopathic Gaucher disease mice.
Volume: 23
Issue: 15
Pages: 3943-57
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Publication
25933409 | J:227541
First Author: Jackson HM
Year: 2015
Journal: PLoS One
Title: DBA/2J genetic background exacerbates spontaneous lethal seizures but lessens amyloid deposition in a mouse model of Alzheimer's disease.
Volume: 10
Issue: 5
Pages: e0125897
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22427994 | J:224126
First Author: Suenaga K
Year: 2012
Journal: PLoS One
Title: Muscleblind-like 1 knockout mice reveal novel splicing defects in the myotonic dystrophy brain.
Volume: 7
Issue: 3
Pages: e33218
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20661273 | J:163095
First Author: Giliberto L
Year: 2010
Journal: PLoS One
Title: Transgenic expression of the amyloid-beta precursor protein-intracellular domain does not induce Alzheimer's Disease-like traits in vivo.
Volume: 5
Issue: 7
Pages: e11609
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34475508 | J:311308
First Author: Kreis A
Year: 2021
Journal: Sci Rep
Title: Overexpression of wild-type human amyloid precursor protein alters GABAergic transmission.
Volume: 11
Issue: 1
Pages: 17600
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Publication
22015470 | J:180329
First Author: Fang F
Year: 2012
Journal: Biochim Biophys Acta
Title: Multi-faced neuroprotective effects of Ginsenoside Rg1 in an Alzheimer mouse model.
Volume: 1822
Issue: 2
Pages: 286-92
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Publication
31727994 | J:284861
First Author: Yuyama K
Year: 2019
Journal: Sci Rep
Title: Plant sphingolipids promote extracellular vesicle release and alleviate amyloid-β pathologies in a mouse model of Alzheimer's disease.
Volume: 9
Issue: 1
Pages: 16827
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22049429 | J:177845
First Author: Hong S
Year: 2011
Journal: J Neurosci
Title: Dynamic analysis of amyloid β-protein in behaving mice reveals opposing changes in ISF versus parenchymal Aβ during age-related plaque formation.
Volume: 31
Issue: 44
Pages: 15861-9
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Publication
34156424 | J:331150
 
First Author: Xu P
Year: 2021
Journal: J Exp Med
Title: GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer's disease.
Volume: 218
Issue: 8
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23467355 | J:196282
First Author: Kim WS
Year: 2013
Journal: J Neurosci
Title: Deletion of Abca7 increases cerebral amyloid-β accumulation in the J20 mouse model of Alzheimer's disease.
Volume: 33
Issue: 10
Pages: 4387-94
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Publication
28438208 | J:315889
First Author: Liu YL
Year: 2017
Journal: Mol Neurodegener
Title: Amelioration of amyloid-β-induced deficits by DcR3 in an Alzheimer's disease model.
Volume: 12
Issue: 1
Pages: 30
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Publication
24807206 | J:214000
 
First Author: Ongali B
Year: 2014
Journal: Neurobiol Dis
Title: Angiotensin II type 1 receptor blocker losartan prevents and rescues cerebrovascular, neuropathological and cognitive deficits in an Alzheimer's disease model.
Volume: 68
Pages: 126-36
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Publication
33482355 | J:310748
 
First Author: Tozzi F
Year: 2021
Journal: Neurobiol Dis
Title: T1AM-TAAR1 signalling protects against OGD-induced synaptic dysfunction in the entorhinal cortex.
Volume: 151
Pages: 105271
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Publication
16837104 | J:123899
First Author: Kalinin S
Year: 2007
Journal: Neurobiol Aging
Title: Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease.
Volume: 28
Issue: 8
Pages: 1206-14
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Publication
29408867 | J:259582
First Author: You JC
Year: 2018
Journal: PLoS One
Title: Genome-wide profiling reveals functional diversification of ∆FosB gene targets in the hippocampus of an Alzheimer's disease mouse model.
Volume: 13
Issue: 2
Pages: e0192508
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23889563 | J:321454
First Author: Zhang L
Year: 2013
Journal: Br J Pharmacol
Title: Endothelial TRPV4 channels mediate dilation of cerebral arteries: impairment and recovery in cerebrovascular pathologies related to Alzheimer's disease.
Volume: 170
Issue: 3
Pages: 661-70
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21307267 | J:169450
First Author: Yao J
Year: 2011
Journal: J Neurosci
Title: Inhibition of amyloid-beta (Abeta) peptide-binding alcohol dehydrogenase-Abeta interaction reduces Abeta accumulation and improves mitochondrial function in a mouse model of Alzheimer's disease.
Volume: 31
Issue: 6
Pages: 2313-20
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Publication
22048123 | J:196555
First Author: Diaz-Hernandez JI
Year: 2012
Journal: Neurobiol Aging
Title: In vivo P2X7 inhibition reduces amyloid plaques in Alzheimer's disease through GSK3β and secretases.
Volume: 33
Issue: 8
Pages: 1816-28
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16452662 | J:105196
First Author: Park JH
Year: 2006
Journal: J Neurosci
Title: Alzheimer precursor protein interaction with the Nogo-66 receptor reduces amyloid-beta plaque deposition.
Volume: 26
Issue: 5
Pages: 1386-95
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Publication
38819065 | J:358642
First Author: Zhang Y
Year: 2025
Journal: Neural Regen Res
Title: Gamma-glutamyl transferase 5 overexpression in cerebrovascular endothelial cells improves brain pathology, cognition, and behavior in APP/PS1 mice.
Volume: 20
Issue: 2
Pages: 533-547
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Publication
23904197 | J:199785
First Author: Saiz-Sanchez D
Year: 2013
Journal: Anat Rec (Hoboken)
Title: Interneurons and beta-amyloid in the olfactory bulb, anterior olfactory nucleus and olfactory tubercle in APPxPS1 transgenic mice model of Alzheimer's disease.
Volume: 296
Issue: 9
Pages: 1413-23
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Publication
36557811 | J:351344
 
First Author: Lim J
Year: 2022
Journal: Molecules
Title: Verbenalin Reduces Amyloid-Beta Peptide Generation in Cellular and Animal Models of Alzheimer's Disease.
Volume: 27
Issue: 24
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23954170 | J:211980
First Author: Ohno M
Year: 2014
Journal: Neurobiol Aging
Title: Nardilysin prevents amyloid plaque formation by enhancing α-secretase activity in an Alzheimer's disease mouse model.
Volume: 35
Issue: 1
Pages: 213-22
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Publication
30243987 | J:269965
 
First Author: Lu MH
Year: 2019
Journal: Exp Neurol
Title: Inhibition of sphingomyelin synthase 1 ameliorates alzheimer-like pathology in APP/PS1 transgenic mice through promoting lysosomal degradation of BACE1.
Volume: 311
Pages: 67-79
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Publication
25044076 | J:218119
First Author: Zhang MY
Year: 2014
Journal: Neurobiol Aging
Title: Lamotrigine attenuates deficits in synaptic plasticity and accumulation of amyloid plaques in APP/PS1 transgenic mice.
Volume: 35
Issue: 12
Pages: 2713-2725
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Publication
29246793 | J:258007
 
First Author: Zhang J
Year: 2018
Journal: Neurosci Lett
Title: Long-term treadmill exercise attenuates Aβ burdens and astrocyte activation in APP/PS1 mouse model of Alzheimer's disease.
Volume: 666
Pages: 70-77
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Publication
25143627 | J:216162
First Author: Bae M
Year: 2014
Journal: J Neurosci
Title: Activation of TRPML1 clears intraneuronal Aβ in preclinical models of HIV infection.
Volume: 34
Issue: 34
Pages: 11485-503
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22188425 | J:290008
First Author: Aso E
Year: 2012
Journal: Brain Pathol
Title: Amyloid generation and dysfunctional immunoproteasome activation with disease progression in animal model of familial Alzheimer's disease.
Volume: 22
Issue: 5
Pages: 636-53
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Publication
19679638 | J:155170
First Author: Zheng W
Year: 2009
Journal: FASEB J
Title: Divalent metal transporter 1 is involved in amyloid precursor protein processing and Abeta generation.
Volume: 23
Issue: 12
Pages: 4207-17
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Publication
28512130 | J:247307
First Author: Mori T
Year: 2017
Journal: J Biol Chem
Title: Combination therapy with octyl gallate and ferulic acid improves cognition and neurodegeneration in a transgenic mouse model of Alzheimer's disease.
Volume: 292
Issue: 27
Pages: 11310-11325
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Publication
30563837 | J:348420
First Author: Mori T
Year: 2019
Journal: J Biol Chem
Title: Combined treatment with the phenolics (-)-epigallocatechin-3-gallate and ferulic acid improves cognition and reduces Alzheimer-like pathology in mice.
Volume: 294
Issue: 8
Pages: 2714-2731
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Publication
36721026 | J:351747
First Author: Matsuzaki M
Year: 2023
Journal: Mol Psychiatry
Title: ADAMTS4 is involved in the production of the Alzheimer disease amyloid biomarker APP669-711.
Volume: 28
Issue: 4
Pages: 1802-1812
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Publication
21670066 | J:175718
First Author: Zhou X
Year: 2011
Journal: FASEB J
Title: Interaction between amyloid precursor protein and Nogo receptors regulates amyloid deposition.
Volume: 25
Issue: 9
Pages: 3146-56
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Publication
29414379 | J:348500
 
First Author: Olsson TT
Year: 2018
Journal: Neurobiol Dis
Title: Prion-like seeding and nucleation of intracellular amyloid-β.
Volume: 113
Pages: 1-10
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Publication
32828017 | J:348488
 
First Author: Wang CY
Year: 2020
Journal: Redox Biol
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