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Search results 4101 to 4200 out of 5246 for App

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Category: Publication
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Type Details Score
Publication
24223757 | J:209326
First Author: Bao XQ
Year: 2013
Journal: PLoS One
Title: FLZ alleviates the memory deficits in transgenic mouse model of Alzheimer's disease via decreasing beta-amyloid production and tau hyperphosphorylation.
Volume: 8
Issue: 11
Pages: e78033
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Publication
23409038 | J:197205
First Author: Mori T
Year: 2013
Journal: PLoS One
Title: Ferulic acid is a nutraceutical β-secretase modulator that improves behavioral impairment and alzheimer-like pathology in transgenic mice.
Volume: 8
Issue: 2
Pages: e55774
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Publication
38729552 | J:349329
 
First Author: Li CL
Year: 2024
Journal: Exp Neurol
Title: STAU1 exhibits a dual function by promoting amyloidogenesis and tau phosphorylation in cultured cells.
Volume: 377
Pages: 114805
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Publication
37239217 | J:348317
 
First Author: Liu Y
Year: 2023
Journal: Brain Sci
Title: DEAD-Box Helicase 17 Promotes Amyloidogenesis by Regulating BACE1 Translation.
Volume: 13
Issue: 5
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Publication
33688799 | J:350983
First Author: Chaudhari K
Year: 2021
Journal: Neurol Res
Title: Early loss of cerebellar Purkinje cells in human and a transgenic mouse model of Alzheimer's disease.
Volume: 43
Issue: 7
Pages: 570-581
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Publication
25157105 | J:217762
First Author: Mori T
Year: 2014
Journal: J Biol Chem
Title: Methylene blue modulates β-secretase, reverses cerebral amyloidosis, and improves cognition in transgenic mice.
Volume: 289
Issue: 44
Pages: 30303-17
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Publication
31479861 | J:285571
 
First Author: Pérez-González R
Year: 2019
Journal: Neurobiol Aging
Title: A pleiotropic role for exosomes loaded with the amyloid β precursor protein carboxyl-terminal fragments in the brain of Down syndrome patients.
Volume: 84
Pages: 26-32
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Publication
30538277 | J:280171
First Author: Bjune JI
Year: 2019
Journal: Int J Obes (Lond)
Title: IRX5 regulates adipocyte amyloid precursor protein and mitochondrial respiration in obesity.
Volume: 43
Issue: 11
Pages: 2151-2162
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Publication
27196068 | J:253089
First Author: Sano O
Year: 2016
Journal: PLoS One
Title: ABCG1 and ABCG4 Suppress γ-Secretase Activity and Amyloid β Production.
Volume: 11
Issue: 5
Pages: e0155400
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Publication
25180020 | J:217062
First Author: Mosser S
Year: 2015
Journal: Hum Mol Genet
Title: The adipocyte differentiation protein APMAP is an endogenous suppressor of Aβ production in the brain.
Volume: 24
Issue: 2
Pages: 371-82
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Publication
23474291 | J:211746
First Author: Tesseur I
Year: 2013
Journal: Neurobiol Aging
Title: Chronic 5-HT4 receptor activation decreases Aβ production and deposition in hAPP/PS1 mice.
Volume: 34
Issue: 7
Pages: 1779-89
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Publication
26458768 | J:229027
First Author: Prokop S
Year: 2015
Journal: J Exp Med
Title: Impact of peripheral myeloid cells on amyloid-β pathology in Alzheimer's disease-like mice.
Volume: 212
Issue: 11
Pages: 1811-8
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Publication
32757390 | J:307504
First Author: Mosser S
Year: 2021
Journal: J Neurochem
Title: Identification of truncated C-terminal fragments of the Alzheimer's disease amyloid protein precursor derived from sequential proteolytic pathways.
Volume: 156
Issue: 6
Pages: 943-956
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Publication
24863668 | J:218079
First Author: Becerril-Ortega J
Year: 2014
Journal: Neurobiol Aging
Title: Iron overload accelerates neuronal amyloid-β production and cognitive impairment in transgenic mice model of Alzheimer's disease.
Volume: 35
Issue: 10
Pages: 2288-301
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Publication
23313508 | J:198070
First Author: Capsoni S
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Dissecting the role of sortilin receptor signaling in neurodegeneration induced by NGF deprivation.
Volume: 431
Issue: 3
Pages: 579-85
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Publication
27312991 | J:264480
First Author: Kolisnyk B
Year: 2017
Journal: Cereb Cortex
Title: Cholinergic Surveillance over Hippocampal RNA Metabolism and Alzheimer's-Like Pathology.
Volume: 27
Issue: 7
Pages: 3553-3567
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Publication
27993242 | J:239385
First Author: Gannon PJ
Year: 2017
Journal: Am J Pathol
Title: HIV Protease Inhibitors Alter Amyloid Precursor Protein Processing via β-Site Amyloid Precursor Protein Cleaving Enzyme-1 Translational Up-Regulation.
Volume: 187
Issue: 1
Pages: 91-109
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Publication
27664080 | J:249644
First Author: Khalfallah O
Year: 2017
Journal: Stem Cells
Title: Depletion of the Fragile X Mental Retardation Protein in Embryonic Stem Cells Alters the Kinetics of Neurogenesis.
Volume: 35
Issue: 2
Pages: 374-385
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Publication
23209315 | J:194631
First Author: Yao J
Year: 2012
Journal: J Exp Med
Title: Neuroprotection by cyclodextrin in cell and mouse models of Alzheimer disease.
Volume: 209
Issue: 13
Pages: 2501-13
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Publication
20676056 | J:163590
First Author: Kuhn PH
Year: 2010
Journal: EMBO J
Title: ADAM10 is the physiologically relevant, constitutive alpha-secretase of the amyloid precursor protein in primary neurons.
Volume: 29
Issue: 17
Pages: 3020-32
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Publication
27325702 | J:330135
First Author: Del Prete D
Year: 2016
Journal: J Biol Chem
Title: Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration.
Volume: 291
Issue: 33
Pages: 17209-27
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Publication
38992438 | J:359044
First Author: Penalva YCM
Year: 2024
Journal: J Biol Chem
Title: Eta-secretase-like processing of the amyloid precursor protein (APP) by the rhomboid protease RHBDL4.
Volume: 300
Issue: 8
Pages: 107541
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Publication
33892080 | J:320451
First Author: Dekeryte R
Year: 2021
Journal: Biochim Biophys Acta Mol Basis Dis
Title: The BACE1 inhibitor LY2886721 improves diabetic phenotypes of BACE1 knock-in mice.
Volume: 1867
Issue: 7
Pages: 166149
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Publication
34277597 | J:329964
 
First Author: Kong Y
Year: 2021
Journal: Front Cell Dev Biol
Title: The Synaptic Vesicle Protein 2A Interacts With Key Pathogenic Factors in Alzheimer's Disease: Implications for Treatment.
Volume: 9
Pages: 609908
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Publication
21597003 | J:177000
First Author: Barthet G
Year: 2011
Journal: FASEB J
Title: Inhibitors of γ-secretase stabilize the complex and differentially affect processing of amyloid precursor protein and other substrates.
Volume: 25
Issue: 9
Pages: 2937-46
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Publication
17098871 | J:117130
First Author: Majercak J
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease.
Volume: 103
Issue: 47
Pages: 17967-72
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Publication
9454589 | J:45497
First Author: Kiefer LL
Year: 1998
Journal: Biochemistry
Title: Melanocortin receptor binding determinants in the agouti protein.
Volume: 37
Issue: 4
Pages: 991-7
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Publication
30086173 | J:273543
First Author: Takasugi N
Year: 2018
Journal: PLoS One
Title: TMEM30A is a candidate interacting partner for the β-carboxyl-terminal fragment of amyloid-β precursor protein in endosomes.
Volume: 13
Issue: 8
Pages: e0200988
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Publication
21329555 | J:287036
First Author: Chen CH
Year: 2012
Journal: Int J Neuropsychopharmacol
Title: Increased NF-κB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease.
Volume: 15
Issue: 1
Pages: 77-90
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Publication
25609612 | J:218891
First Author: Vinograd-Byk H
Year: 2015
Journal: J Neurosci
Title: The spinal muscular atrophy with pontocerebellar hypoplasia gene VRK1 regulates neuronal migration through an amyloid-β precursor protein-dependent mechanism.
Volume: 35
Issue: 3
Pages: 936-42
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Publication
18429932 | J:206916
First Author: Chan SL
Year: 2008
Journal: J Neurochem
Title: ATP-binding cassette transporter A7 regulates processing of amyloid precursor protein in vitro.
Volume: 106
Issue: 2
Pages: 793-804
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Publication
11544248 | J:114050
First Author: Kimberly WT
Year: 2001
Journal: J Biol Chem
Title: The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner.
Volume: 276
Issue: 43
Pages: 40288-92
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Publication
30647129 | J:352407
First Author: Dlouhy AC
Year: 2019
Journal: J Biol Chem
Title: Fluorescence resonance energy transfer links membrane ferroportin, hephaestin but not ferroportin, amyloid precursor protein complex with iron efflux.
Volume: 294
Issue: 11
Pages: 4202-4214
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Publication
10716654 | J:61271
First Author: Sommer B
Year: 2000
Journal: Rev Neurosci
Title: Transgenic approaches to model Alzheimer's disease.
Volume: 11
Issue: 1
Pages: 47-51
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Publication
10718147 | J:61268
First Author: Dodart JC
Year: 2000
Journal: Rev Neurosci
Title: The beta-amyloid precursor protein and its derivatives: from biology to learning and memory processes.
Volume: 11
Issue: 2-3
Pages: 75-93
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Publication
10727777 | J:61243
First Author: van Leuven F
Year: 2000
Journal: Prog Neurobiol
Title: Single and multiple transgenic mice as models for Alzheimer's disease.
Volume: 61
Issue: 3
Pages: 305-12
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Publication
1900367 | J:11024
First Author: Fisher S
Year: 1991
Journal: Proc Natl Acad Sci U S A
Title: Expression of the amyloid precursor protein gene in mouse oocytes and embryos.
Volume: 88
Issue: 5
Pages: 1779-82
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Publication
8188705 | J:18192
First Author: Sandbrink R
Year: 1994
Journal: J Biol Chem
Title: Similar alternative splicing of a non-homologous domain in beta A4-amyloid protein precursor-like proteins.
Volume: 269
Issue: 19
Pages: 14227-34
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Publication
7929392 | J:21849
First Author: Bush AI
Year: 1994
Journal: J Biol Chem
Title: The amyloid beta-protein precursor and its mammalian homologues. Evidence for a zinc-modulated heparin-binding superfamily.
Volume: 269
Issue: 43
Pages: 26618-21
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Publication
7959697 | J:21776
First Author: Gregor P
Year: 1994
Journal: Hum Genet
Title: Genetic and physical mapping of the GLUR5 glutamate receptor gene on human chromosome 21.
Volume: 94
Issue: 5
Pages: 565-70
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Publication
8575820 | J:35330
First Author: Maeda YY
Year: 1996
Journal: Immunogenetics
Title: Two genes controlling acute phase responses by the antitumor polysacch aride, lentinan.
Volume: 43
Issue: 4
Pages: 215-9
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Publication
8626761 | J:31464
First Author: Nitsch RM
Year: 1996
Journal: J Biol Chem
Title: Serotonin 5-HT2a and 5-HT2c receptors stimulate amyloid precursor protein ectodomain secretion.
Volume: 271
Issue: 8
Pages: 4188-94
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Publication
9404712 | J:44310
First Author: Mattson MP
Year: 1997
Journal: J Neurosci Res
Title: Cell and molecular neurobiology of presenilins: a role for the endoplasmic reticulum in the pathogenesis of Alzheimer's disease?
Volume: 50
Issue: 4
Pages: 505-13
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Publication
12562529 | J:81775
First Author: Hashimoto Y
Year: 2003
Journal: J Neurochem
Title: Involvement of c-Jun N-terminal kinase in amyloid precursor protein-mediated neuronal cell death.
Volume: 84
Issue: 4
Pages: 864-77
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Publication
12746438 | J:84534
First Author: Zhong P
Year: 2003
Journal: J Biol Chem
Title: Impaired modulation of GABAergic transmission by muscarinic receptors in a mouse transgenic model of Alzheimer's disease.
Volume: 278
Issue: 29
Pages: 26888-96
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Publication
15347683 | J:94983
First Author: Liao YF
Year: 2004
Journal: J Biol Chem
Title: Tumor necrosis factor-alpha, interleukin-1beta, and interferon-gamma stimulate gamma-secretase-mediated cleavage of amyloid precursor protein through a JNK-dependent MAPK pathway.
Volume: 279
Issue: 47
Pages: 49523-32
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Publication
16233955 | J:104544
First Author: Carter TL
Year: 2006
Journal: Neurosci Lett
Title: Brain neprilysin activity and susceptibility to transgene-induced Alzheimer amyloidosis.
Volume: 392
Issue: 3
Pages: 235-9
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Publication
12023290 | J:113988
First Author: Taru H
Year: 2002
Journal: J Biol Chem
Title: Differential roles of JIP scaffold proteins in the modulation of amyloid precursor protein metabolism.
Volume: 277
Issue: 30
Pages: 27567-74
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Publication
16638748 | J:116900
First Author: Hoe HS
Year: 2006
Journal: J Biol Chem
Title: FE65 interaction with the ApoE receptor ApoEr2.
Volume: 281
Issue: 34
Pages: 24521-30
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Publication
17348862 | J:120072
First Author: Lin P
Year: 2007
Journal: J Neurochem
Title: Calnuc binds to Alzheimer's beta-amyloid precursor protein and affects its biogenesis.
Volume: 100
Issue: 6
Pages: 1505-14
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Publication
11303783 | J:121327
First Author: Martys-Zage JL
Year: 2000
Journal: J Mol Neurosci
Title: Requirement for presenilin 1 in facilitating lagged 2-mediated endoproteolysis and signaling of notch 1.
Volume: 15
Issue: 3
Pages: 189-204
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Publication
7882025 | J:123334
First Author: Mucke L
Year: 1994
Journal: Brain Res
Title: Synaptotrophic effects of human amyloid beta protein precursors in the cortex of transgenic mice.
Volume: 666
Issue: 2
Pages: 151-67
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Publication
17623042 | J:128057
First Author: Englund H
Year: 2007
Journal: J Neurochem
Title: Sensitive ELISA detection of amyloid-beta protofibrils in biological samples.
Volume: 103
Issue: 1
Pages: 334-45
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Publication
18485495 | J:136317
First Author: Galvan V
Year: 2008
Journal: Behav Brain Res
Title: Long-term prevention of Alzheimer's disease-like behavioral deficits in PDAPP mice carrying a mutation in Asp664.
Volume: 191
Issue: 2
Pages: 246-55
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Publication
18367332 | J:136646
First Author: Dehvari N
Year: 2008
Journal: Neurosci Lett
Title: Presenilin regulates extracellular regulated kinase (Erk) activity by a protein kinase C alpha dependent mechanism.
Volume: 436
Issue: 1
Pages: 77-80
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Publication
18436531 | J:138182
First Author: Shen C
Year: 2008
Journal: J Biol Chem
Title: Hydrogen peroxide promotes Abeta production through JNK-dependent activation of gamma-secretase.
Volume: 283
Issue: 25
Pages: 17721-30
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Publication
18669616 | J:139936
First Author: Paulson JB
Year: 2008
Journal: Am J Pathol
Title: Amyloid plaque and neurofibrillary tangle pathology in a regulatable mouse model of Alzheimer's disease.
Volume: 173
Issue: 3
Pages: 762-72
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Publication
18784309 | J:141259
First Author: Nicolakakis N
Year: 2008
Journal: J Neurosci
Title: Complete rescue of cerebrovascular function in aged Alzheimer's disease transgenic mice by antioxidants and pioglitazone, a peroxisome proliferator-activated receptor gamma agonist.
Volume: 28
Issue: 37
Pages: 9287-96
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Publication
19232329 | J:148200
 
First Author: Zhang Q
Year: 2009
Journal: Brain Res
Title: Senescence accelerated mouse strain is sensitive to neurodegeneration induced by mild impairment of oxidative metabolism.
Volume: 1264
Pages: 111-8
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Publication
19049493 | J:148977
First Author: Cuesta A
Year: 2009
Journal: Biochem J
Title: The tumour suppressor p53 regulates the expression of amyloid precursor protein (APP).
Volume: 418
Issue: 3
Pages: 643-50
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Publication
19410642 | J:151188
First Author: Castillo CA
Year: 2009
Journal: Exp Gerontol
Title: Age-related expression of adenosine receptors in brain from the senescence-accelerated mouse.
Volume: 44
Issue: 6-7
Pages: 453-61
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Publication
19889971 | J:154760
First Author: Dunys J
Year: 2009
Journal: J Cell Sci
Title: p53-dependent control of transactivation of the Pen2 promoter by presenilins.
Volume: 122
Issue: Pt 21
Pages: 4003-8
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Publication
19625658 | J:154874
First Author: Huttunen HJ
Year: 2009
Journal: FASEB J
Title: Inhibition of acyl-coenzyme A: cholesterol acyl transferase modulates amyloid precursor protein trafficking in the early secretory pathway.
Volume: 23
Issue: 11
Pages: 3819-28
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Publication
20025930 | J:156882
First Author: Hashimoto T
Year: 2010
Journal: Neurosci Lett
Title: Age-dependent increase in lysosome-associated membrane protein 1 and early-onset behavioral deficits in APPSL transgenic mouse model of Alzheimer's disease.
Volume: 469
Issue: 2
Pages: 273-7
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Publication
21613482 | J:173328
First Author: Winton MJ
Year: 2011
Journal: J Neurosci
Title: Intraneuronal APP, not free Aβ peptides in 3xTg-AD mice: implications for tau versus Aβ-mediated Alzheimer neurodegeneration.
Volume: 31
Issue: 21
Pages: 7691-9
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Publication
21534960 | J:175582
First Author: Minami SS
Year: 2011
Journal: J Neurochem
Title: Fyn kinase regulates the association between amyloid precursor protein and Dab1 by promoting their localization to detergent-resistant membranes.
Volume: 118
Issue: 5
Pages: 879-90
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Publication
21989385 | J:180080
First Author: Schmidt V
Year: 2012
Journal: EMBO J
Title: Quantitative modelling of amyloidogenic processing and its influence by SORLA in Alzheimer's disease.
Volume: 31
Issue: 1
Pages: 187-200
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Publication
22279231 | J:180578
First Author: Fjorback AW
Year: 2012
Journal: J Neurosci
Title: Retromer binds the FANSHY sorting motif in SorLA to regulate amyloid precursor protein sorting and processing.
Volume: 32
Issue: 4
Pages: 1467-80
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Publication
22192143 | J:184338
First Author: Fragkouli A
Year: 2012
Journal: J Neurochem
Title: Enhanced neuronal plasticity and elevated endogenous sAPPα levels in mice over-expressing MMP9.
Volume: 121
Issue: 2
Pages: 239-51
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Publication
22178988 | J:184401
 
First Author: Jolivalt CG
Year: 2012
Journal: Neuroscience
Title: Similar pattern of peripheral neuropathy in mouse models of type 1 diabetes and Alzheimer's disease.
Volume: 202
Pages: 405-12
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Publication
22505025 | J:184696
First Author: Chávez-Gutiérrez L
Year: 2012
Journal: EMBO J
Title: The mechanism of γ-Secretase dysfunction in familial Alzheimer disease.
Volume: 31
Issue: 10
Pages: 2261-74
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Publication
22586122 | J:184754
First Author: Zhang X
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Identification of a tetratricopeptide repeat-like domain in the nicastrin subunit of γ-secretase using synthetic antibodies.
Volume: 109
Issue: 22
Pages: 8534-9
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Publication
23238734 | J:192014
First Author: Page RM
Year: 2012
Journal: J Neurosci
Title: Loss of PAFAH1B2 reduces amyloid-β generation by promoting the degradation of amyloid precursor protein C-terminal fragments.
Volume: 32
Issue: 50
Pages: 18204-14
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23197725 | J:193050
First Author: Chabrier MA
Year: 2012
Journal: J Neurosci
Title: Soluble aβ promotes wild-type tau pathology in vivo.
Volume: 32
Issue: 48
Pages: 17345-50
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Publication
23658180 | J:198432
First Author: Li W
Year: 2013
Journal: J Neurosci
Title: Elevation of brain magnesium prevents and reverses cognitive deficits and synaptic loss in Alzheimer's disease mouse model.
Volume: 33
Issue: 19
Pages: 8423-41
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Publication
22771797 | J:201292
First Author: Teranishi Y
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Erlin-2 is associated with active γ-secretase in brain and affects amyloid β-peptide production.
Volume: 424
Issue: 3
Pages: 476-81
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Publication
23926111 | J:205970
First Author: Wang H
Year: 2013
Journal: J Biol Chem
Title: COPS5 (Jab1) protein increases β site processing of amyloid precursor protein and amyloid β peptide generation by stabilizing RanBP9 protein levels.
Volume: 288
Issue: 37
Pages: 26668-77
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Publication
23872114 | J:210772
First Author: Chua LM
Year: 2013
Journal: Biochem Biophys Res Commun
Title: The Kunitz-protease inhibitor domain in amyloid precursor protein reduces cellular mitochondrial enzymes expression and function.
Volume: 437
Issue: 4
Pages: 642-7
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Publication
24440055 | J:212059
 
First Author: Chabrier MA
Year: 2014
Journal: Neurobiol Dis
Title: Synergistic effects of amyloid-beta and wild-type human tau on dendritic spine loss in a floxed double transgenic model of Alzheimer's disease.
Volume: 64
Pages: 107-17
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Publication
23624141 | J:214201
 
First Author: Kitaoka K
Year: 2013
Journal: Neuropharmacology
Title: The retinoic acid receptor agonist Am80 increases hippocampal ADAM10 in aged SAMP8 mice.
Volume: 72
Pages: 58-65
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Publication
24808180 | J:216030
First Author: Karaca I
Year: 2014
Journal: J Biol Chem
Title: Deficiency of sphingosine-1-phosphate lyase impairs lysosomal metabolism of the amyloid precursor protein.
Volume: 289
Issue: 24
Pages: 16761-72
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Publication
25939386 | J:224097
First Author: Wang Y
Year: 2015
Journal: Mol Cell Biol
Title: Overexpression of the Insulin-Like Growth Factor II Receptor Increases β-Amyloid Production and Affects Cell Viability.
Volume: 35
Issue: 14
Pages: 2368-84
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Publication
26896628 | J:231974
First Author: Ueda N
Year: 2016
Journal: J Neurochem
Title: Retromer and Rab2-dependent trafficking mediate PS1 degradation by proteasomes in endocytic disturbance.
Volume: 137
Issue: 4
Pages: 647-58
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Publication
26911678 | J:233018
First Author: Lu J
Year: 2016
Journal: Hum Mol Genet
Title: Global hypermethylation in fetal cortex of Down syndrome due to DNMT3L overexpression.
Volume: 25
Issue: 9
Pages: 1714-27
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Publication
27179390 | J:234017
First Author: Kimura N
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