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Search results 501 to 600 out of 5246 for App

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Category: Publication
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Type Details Score
Publication
30422705 | J:273467
First Author: Kulas JA
Year: 2019
Journal: Am J Physiol Endocrinol Metab
Title: Ablation of amyloid precursor protein increases insulin-degrading enzyme levels and activity in brain and peripheral tissues.
Volume: 316
Issue: 1
Pages: E106-E120
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Publication
29101243 | J:336388
First Author: Wang Z
Year: 2017
Journal: J Neurosci
Title: Human Brain-Derived Aβ Oligomers Bind to Synapses and Disrupt Synaptic Activity in a Manner That Requires APP.
Volume: 37
Issue: 49
Pages: 11947-11966
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Publication
35928998 | J:327088
 
First Author: Martinsson I
Year: 2022
Journal: Front Aging Neurosci
Title: Aβ/Amyloid Precursor Protein-Induced Hyperexcitability and Dysregulation of Homeostatic Synaptic Plasticity in Neuron Models of Alzheimer's Disease.
Volume: 14
Pages: 946297
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Publication
10219973 | J:54292
First Author: Seabrook GR
Year: 1999
Journal: Neuropharmacology
Title: Mechanisms contributing to the deficits in hippocampal synaptic plasticity in mice lacking amyloid precursor protein.
Volume: 38
Issue: 3
Pages: 349-59
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Publication
22279552 | J:184236
First Author: Ho T
Year: 2012
Journal: PLoS One
Title: Amyloid precursor protein is required for normal function of the rod and cone pathways in the mouse retina.
Volume: 7
Issue: 1
Pages: e29892
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Publication
26447481 | J:243693
First Author: Carrano A
Year: 2015
Journal: PLoS One
Title: Altered Innate Immune and Glial Cell Responses to Inflammatory Stimuli in Amyloid Precursor Protein Knockout Mice.
Volume: 10
Issue: 10
Pages: e0140210
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Publication
28710249 | J:336468
First Author: Kulas JA
Year: 2017
Journal: J Endocrinol
Title: Amyloid precursor protein in pancreatic islets.
Volume: 235
Issue: 1
Pages: 49-67
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Publication
25392299 | J:329710
First Author: Niederst ED
Year: 2015
Journal: Mol Biol Cell
Title: Axonal amyloid precursor protein and its fragments undergo somatodendritic endocytosis and processing.
Volume: 26
Issue: 2
Pages: 205-17
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Publication
25926793 | J:237753
 
First Author: Frick A
Year: 2015
Journal: Front Pharmacol
Title: Identifying genes that mediate anthracyline toxicity in immune cells.
Volume: 6
Pages: 62
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Publication
10531420 | J:119903
First Author: White AR
Year: 1999
Journal: J Neurosci
Title: The Alzheimer's disease amyloid precursor protein modulates copper-induced toxicity and oxidative stress in primary neuronal cultures.
Volume: 19
Issue: 21
Pages: 9170-9
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Publication
15147316 | J:90296
First Author: Kawasumi M
Year: 2004
Journal: Eur J Neurosci
Title: Targeted introduction of V642I mutation in amyloid precursor protein gene causes functional abnormality resembling early stage of Alzheimer's disease in aged mice.
Volume: 19
Issue: 10
Pages: 2826-38
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Publication
27572463 | J:237934
First Author: Zou C
Year: 2016
Journal: EMBO J
Title: Amyloid precursor protein maintains constitutive and adaptive plasticity of dendritic spines in adult brain by regulating D-serine homeostasis.
Volume: 35
Issue: 20
Pages: 2213-2222
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Publication
30667091 | J:273725
First Author: Montagna E
Year: 2019
Journal: Glia
Title: In vivo Ca2+ imaging of astrocytic microdomains reveals a critical role of the amyloid precursor protein for mitochondria.
Volume: 67
Issue: 5
Pages: 985-998
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Publication
10203685 | J:101976
First Author: Steinbach JP
Year: 1998
Journal: Cell Death Differ
Title: Hypersensitivity to seizures in beta-amyloid precursor protein deficient mice.
Volume: 5
Issue: 10
Pages: 858-66
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Publication
17634375 | J:123316
First Author: Ring S
Year: 2007
Journal: J Neurosci
Title: The secreted beta-amyloid precursor protein ectodomain APPs alpha is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice.
Volume: 27
Issue: 29
Pages: 7817-26
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Publication
18403052 | J:156809
First Author: Konietzko U
Year: 2010
Journal: Neurobiol Aging
Title: Co-localization of the amyloid precursor protein and Notch intracellular domains in nuclear transcription factories.
Volume: 31
Issue: 1
Pages: 58-73
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Publication
26905287 | J:254129
 
First Author: Zhang X
Year: 2016
Journal: Sci Rep
Title: Impaired theta-gamma coupling in APP-deficient mice.
Volume: 6
Pages: 21948
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Publication
25911278 | J:224496
First Author: Mahler J
Year: 2015
Journal: Neurobiol Aging
Title: Endogenous murine Aβ increases amyloid deposition in APP23 but not in APPPS1 transgenic mice.
Volume: 36
Issue: 7
Pages: 2241-2247
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Publication
36629784 | J:334692
First Author: Wang J
Year: 2023
Journal: FASEB J
Title: Distinct effects of SDC3 and FGFRL1 on selective neurodegeneration in AD and PD.
Volume: 37
Issue: 2
Pages: e22773
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Publication
17183681 | J:129354
 
First Author: Sano Y
Year: 2006
Journal: PLoS One
Title: Physiological mouse brain Abeta levels are not related to the phosphorylation state of threonine-668 of Alzheimer's APP.
Volume: 1
Pages: e51
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Publication
20339537 | J:158883
First Author: Gengler S
Year: 2010
Journal: PLoS One
Title: Synaptic plasticity in the hippocampus of a APP/PS1 mouse model of Alzheimer's disease is impaired in old but not young mice.
Volume: 5
Issue: 3
Pages: e9764
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Publication
17884188 | J:127367
First Author: Senechal Y
Year: 2008
Journal: Behav Brain Res
Title: Amyloid precursor protein knockout mice show age-dependent deficits in passive avoidance learning.
Volume: 186
Issue: 1
Pages: 126-32
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Publication
25904844 | J:242677
 
First Author: La Rosa LR
Year: 2015
Journal: Front Cell Neurosci
Title: Y682G Mutation of Amyloid Precursor Protein Promotes Endo-Lysosomal Dysfunction by Disrupting APP-SorLA Interaction.
Volume: 9
Pages: 109
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Publication
23020178 | J:222341
First Author: Matrone C
Year: 2012
Journal: Aging Cell
Title: Tyr682 in the Aβ-precursor protein intracellular domain regulates synaptic connectivity, cholinergic function, and cognitive performance.
Volume: 11
Issue: 6
Pages: 1084-93
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Publication
29674739 | J:263094
First Author: Shah D
Year: 2018
Journal: Sci Rep
Title: Spatial reversal learning defect coincides with hypersynchronous telencephalic BOLD functional connectivity in APPNL-F/NL-F knock-in mice.
Volume: 8
Issue: 1
Pages: 6264
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Publication
34379812 | J:353065
First Author: Hata S
Year: 2021
Journal: J Neurochem
Title: Suppression of amyloid-β secretion from neurons by cis-9, trans-11-octadecadienoic acid, an isomer of conjugated linoleic acid.
Volume: 159
Issue: 3
Pages: 603-617
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Publication
34620254 | J:311720
First Author: Xie J
Year: 2021
Journal: Acta Neuropathol Commun
Title: Low-grade peripheral inflammation affects brain pathology in the AppNL-G-Fmouse model of Alzheimer's disease.
Volume: 9
Issue: 1
Pages: 163
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Publication
38167640 | J:346101
First Author: Yamada H
Year: 2024
Journal: Sci Rep
Title: The long-term effects of heated tobacco product exposure on the central nervous system in a mouse model of prodromal Alzheimer's disease.
Volume: 14
Issue: 1
Pages: 227
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Publication
37978387 | J:357361
First Author: Gaunt JR
Year: 2023
Journal: J Neuroinflammation
Title: Cytokine enrichment in deep cerebellar nuclei is contributed by multiple glial populations and linked to reduced amyloid plaque pathology.
Volume: 20
Issue: 1
Pages: 269
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Publication
39171353 | J:354794
First Author: Norambuena A
Year: 2024
Journal: Alzheimers Dement
Title: Disrupted mitochondrial response to nutrients is a presymptomatic event in the cortex of the APP(SAA) knock-in mouse model of Alzheimer's disease.
Volume: 20
Issue: 10
Pages: 6844-6859
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Publication
10845772 | J:63791
First Author: Akaaboune M
Year: 2000
Journal: Mol Cell Neurosci
Title: Developmental regulation of amyloid precursor protein at the neuromuscular junction in mouse skeletal muscle.
Volume: 15
Issue: 4
Pages: 355-67
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Publication
11818564 | J:74511
First Author: Koistinaho M
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Beta-amyloid precursor protein transgenic mice that harbor diffuse A beta deposits but do not form plaques show increased ischemic vulnerability: role of inflammation.
Volume: 99
Issue: 3
Pages: 1610-5
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Publication
1671712 | J:42430
First Author: Goate A
Year: 1991
Journal: Nature
Title: Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease.
Volume: 349
Issue: 6311
Pages: 704-6
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18160654 | J:130970
First Author: Young-Pearse TL
Year: 2007
Journal: J Neurosci
Title: A critical function for beta-amyloid precursor protein in neuronal migration revealed by in utero RNA interference.
Volume: 27
Issue: 52
Pages: 14459-69
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Publication
22519988 | J:318100
First Author: Corrigan F
Year: 2012
Journal: J Neurochem
Title: sAPPα rescues deficits in amyloid precursor protein knockout mice following focal traumatic brain injury.
Volume: 122
Issue: 1
Pages: 208-20
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Publication
30612335 | J:318549
First Author: Cimdins K
Year: 2019
Journal: Mol Neurobiol
Title: Amyloid Precursor Protein Mediates Neuronal Protection from Rotenone Toxicity.
Volume: 56
Issue: 8
Pages: 5471-5482
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Publication
28464981 | J:244243
 
First Author: Vanden Dries V
Year: 2017
Journal: Neurobiol Aging
Title: Amyloid precursor protein reduction enhances the formation of neurofibrillary tangles in a mutant tau transgenic mouse model.
Volume: 55
Pages: 202-212
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Publication
33028637 | J:299408
First Author: Lingel A
Year: 2020
Journal: J Biol Chem
Title: Amyloid precursor protein is a restriction factor that protects against Zika virus infection in mammalian brains.
Volume: 295
Issue: 50
Pages: 17114-17127
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Publication
21368296 | J:174250
First Author: Linde CI
Year: 2011
Journal: Am J Physiol Cell Physiol
Title: Dysregulation of Ca2+ signaling in astrocytes from mice lacking amyloid precursor protein.
Volume: 300
Issue: 6
Pages: C1502-12
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Publication
16354912 | J:103996
First Author: Han P
Year: 2005
Journal: J Neurosci
Title: Suppression of cyclin-dependent kinase 5 activation by amyloid precursor protein: a novel excitoprotective mechanism involving modulation of tau phosphorylation.
Volume: 25
Issue: 50
Pages: 11542-52
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Publication
24066134 | J:206037
First Author: Hendrickx A
Year: 2013
Journal: PLoS One
Title: Epigenetic induction of EGR-1 expression by the amyloid precursor protein during exposure to novelty.
Volume: 8
Issue: 9
Pages: e74305
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Publication
23691241 | J:204265
First Author: Sosa LJ
Year: 2013
Journal: PLoS One
Title: Amyloid precursor protein is an autonomous growth cone adhesion molecule engaged in contact guidance.
Volume: 8
Issue: 5
Pages: e64521
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8798542 | J:35500
First Author: Reaume AG
Year: 1996
Journal: J Biol Chem
Title: Enhanced amyloidogenic processing of the beta-amyloid precursor protein in gene-targeted mice bearing the Swedish familial Alzheimer's disease mutations and a "humanized" Abeta sequence.
Volume: 271
Issue: 38
Pages: 23380-8
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Publication
19692615 | J:151919
First Author: Bittner T
Year: 2009
Journal: J Neurosci
Title: Gamma-secretase inhibition reduces spine density in vivo via an amyloid precursor protein-dependent pathway.
Volume: 29
Issue: 33
Pages: 10405-9
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Publication
33636388 | J:306945
 
First Author: Jiang M
Year: 2021
Journal: Neurobiol Dis
Title: Impaired neurogenesis in the hippocampus of an adult VPS35 mutant mouse model of Parkinson's disease through interaction with APP.
Volume: 153
Pages: 105313
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Publication
18823960 | J:147624
 
First Author: Senechal Y
Year: 2008
Journal: Brain Res
Title: Increased exploratory activity of APP23 mice in a novel environment is reversed by siRNA.
Volume: 1243
Pages: 124-33
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Publication
26718890 | J:239268
First Author: Stanga S
Year: 2016
Journal: FASEB J
Title: APP-dependent glial cell line-derived neurotrophic factor gene expression drives neuromuscular junction formation.
Volume: 30
Issue: 5
Pages: 1696-711
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Publication
33309748 | J:307497
 
First Author: Tanaka T
Year: 2021
Journal: Exp Neurol
Title: Early-life stress induces the development of Alzheimer's disease pathology via angiopathy.
Volume: 337
Pages: 113552
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Publication
10671319 | J:60489
First Author: Kumar-Singh S
Year: 2000
Journal: Neurobiol Dis
Title: Behavioral disturbances without amyloid deposits in mice overexpressing human amyloid precursor protein with Flemish (A692G) or Dutch (E693Q) mutation.
Volume: 7
Issue: 1
Pages: 9-22
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Publication
1560239 | J:125
First Author: Fukuchi K
Year: 1992
Journal: J Neurochem
Title: Increased expression of beta-amyloid protein precursor and microtubule-associated protein tau during the differentiation of murine embryonal carcinoma cells.
Volume: 58
Issue: 5
Pages: 1863-73
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Publication
18272596 | J:159137
First Author: Osterfield M
Year: 2008
Journal: Development
Title: Interaction of amyloid precursor protein with contactins and NgCAM in the retinotectal system.
Volume: 135
Issue: 6
Pages: 1189-99
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Publication
24358169 | J:211143
First Author: Hasebe N
Year: 2013
Journal: PLoS One
Title: Soluble β-amyloid Precursor Protein Alpha binds to p75 neurotrophin receptor to promote neurite outgrowth.
Volume: 8
Issue: 12
Pages: e82321
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Publication
11224535 | J:67736
First Author: Luo Y
Year: 2001
Journal: Nat Neurosci
Title: Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation.
Volume: 4
Issue: 3
Pages: 231-2
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14664815 | J:86936
First Author: Harrison SM
Year: 2003
Journal: Mol Cell Neurosci
Title: BACE1 (beta-secretase) transgenic and knockout mice: identification of neurochemical deficits and behavioral changes.
Volume: 24
Issue: 3
Pages: 646-55
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Publication
21880018 | J:179224
First Author: Meakin PJ
Year: 2012
Journal: Biochem J
Title: Reduction in BACE1 decreases body weight, protects against diet-induced obesity and enhances insulin sensitivity in mice.
Volume: 441
Issue: 1
Pages: 285-96
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Publication
15824102 | J:100272
First Author: Wong HK
Year: 2005
Journal: J Biol Chem
Title: beta Subunits of voltage-gated sodium channels are novel substrates of beta-site amyloid precursor protein-cleaving enzyme (BACE1) and gamma-secretase.
Volume: 280
Issue: 24
Pages: 23009-17
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Publication
25716831 | J:219853
First Author: Hessler S
Year: 2015
Journal: J Neurosci
Title: β-Secretase BACE1 regulates hippocampal and reconstituted M-currents in a β-subunit-like fashion.
Volume: 35
Issue: 8
Pages: 3298-311
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Publication
28785723 | J:255943
 
First Author: Wang B
Year: 2017
Journal: eNeuro
Title: The Amyloid Precursor Protein Is a Conserved Receptor for Slit to Mediate Axon Guidance.
Volume: 4
Issue: 3
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21435241 | J:170309
 
First Author: Aydin D
Year: 2011
Journal: BMC Genomics
Title: Comparative transcriptome profiling of amyloid precursor protein family members in the adult cortex.
Volume: 12
Pages: 160
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16049335 | J:99946
First Author: Miao J
Year: 2005
Journal: Am J Pathol
Title: Cerebral microvascular amyloid beta protein deposition induces vascular degeneration and neuroinflammation in transgenic mice expressing human vasculotropic mutant amyloid beta precursor protein.
Volume: 167
Issue: 2
Pages: 505-15
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38462606 | J:347713
First Author: Zhong MZ
Year: 2024
Journal: Mol Neurodegener
Title: Updates on mouse models of Alzheimer's disease.
Volume: 19
Issue: 1
Pages: 23
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Publication
21857966 | J:176368
First Author: Li B
Year: 2011
Journal: PLoS One
Title: WNT5A signaling contributes to Aβ-induced neuroinflammation and neurotoxicity.
Volume: 6
Issue: 8
Pages: e22920
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12074840 | J:101575
First Author: Fukami S
Year: 2002
Journal: Neurosci Res
Title: Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology.
Volume: 43
Issue: 1
Pages: 39-56
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Publication
22036569 | J:178689
First Author: Wu J
Year: 2011
Journal: Cell
Title: Arc/Arg3.1 regulates an endosomal pathway essential for activity-dependent β-amyloid generation.
Volume: 147
Issue: 3
Pages: 615-28
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Publication
12843267 | J:84370
First Author: Burns M
Year: 2003
Journal: J Neurosci
Title: Presenilin redistribution associated with aberrant cholesterol transport enhances beta-amyloid production in vivo.
Volume: 23
Issue: 13
Pages: 5645-9
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18278038 | J:145671
First Author: Ma QH
Year: 2008
Journal: Nat Cell Biol
Title: A TAG1-APP signalling pathway through Fe65 negatively modulates neurogenesis.
Volume: 10
Issue: 3
Pages: 283-94
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20817278 | J:167925
First Author: Duce JA
Year: 2010
Journal: Cell
Title: Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease.
Volume: 142
Issue: 6
Pages: 857-67
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Publication
16698938 | J:110206
First Author: Choi DS
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: PKCepsilon increases endothelin converting enzyme activity and reduces amyloid plaque pathology in transgenic mice.
Volume: 103
Issue: 21
Pages: 8215-20
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Publication
28588032 | J:262463
First Author: Acx H
Year: 2017
Journal: EMBO Mol Med
Title: Inactivation of γ-secretases leads to accumulation of substrates and non-Alzheimer neurodegeneration.
Volume: 9
Issue: 8
Pages: 1088-1099
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Publication
16480949 | J:175358
First Author: Chen TY
Year: 2006
Journal: Biochem Biophys Res Commun
Title: The intracellular domain of amyloid precursor protein interacts with flotillin-1, a lipid raft protein.
Volume: 342
Issue: 1
Pages: 266-72
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Publication
26960425 | J:269561
First Author: Yu Y
Year: 2016
Journal: Neurosci Bull
Title: Yeast Two-Hybrid Screening for Proteins that Interact with the Extracellular Domain of Amyloid Precursor Protein.
Volume: 32
Issue: 2
Pages: 171-6
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10460257 | J:57129
First Author: Homayouni R
Year: 1999
Journal: J Neurosci
Title: Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1.
Volume: 19
Issue: 17
Pages: 7507-15
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17556541 | J:122380
First Author: Zhang YW
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Presenilin/gamma-secretase-dependent processing of beta-amyloid precursor protein regulates EGF receptor expression.
Volume: 104
Issue: 25
Pages: 10613-8
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17709753 | J:143819
First Author: Wang B
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Amyolid precursor protein mediates presynaptic localization and activity of the high-affinity choline transporter.
Volume: 104
Issue: 35
Pages: 14140-5
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20855613 | J:165417
First Author: Li H
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP.
Volume: 107
Issue: 40
Pages: 17362-7
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Publication
21084623 | J:166440
First Author: Norstrom EM
Year: 2010
Journal: J Neurosci
Title: Identification of NEEP21 as a ß-amyloid precursor protein-interacting protein in vivo that modulates amyloidogenic processing in vitro.
Volume: 30
Issue: 46
Pages: 15677-85
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18650440 | J:142323
First Author: Li H
Year: 2008
Journal: J Biol Chem
Title: Structure of the C-terminal phosphotyrosine interaction domain of Fe65L1 complexed with the cytoplasmic tail of amyloid precursor protein reveals a novel peptide binding mode.
Volume: 283
Issue: 40
Pages: 27165-78
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7708769 | J:24161
First Author: Brugg B
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: Inflammatory processes induce beta-amyloid precursor protein changes in mouse brain.
Volume: 92
Issue: 7
Pages: 3032-5
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Publication
21303697 | J:172769
First Author: Nunes A
Year: 2011
Journal: Neurobiol Dis
Title: Loss of amyloid precursor protein in a mouse model of Niemann-Pick type C disease exacerbates its phenotype and disrupts tau homeostasis.
Volume: 42
Issue: 3
Pages: 349-59
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Publication
28611024 | J:244865
First Author: Canobbio I
Year: 2017
Journal: Blood
Title: Platelet amyloid precursor protein is a modulator of venous thromboembolism in mice.
Volume: 130
Issue: 4
Pages: 527-536
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Publication
17032642 | J:117646
First Author: Sano Y
Year: 2006
Journal: J Biol Chem
Title: Enhanced amyloidogenic metabolism of the amyloid beta-protein precursor in the X11L-deficient mouse brain.
Volume: 281
Issue: 49
Pages: 37853-60
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Publication
24806670 | J:211049
First Author: Olsen O
Year: 2014
Journal: J Neurosci
Title: Genetic analysis reveals that amyloid precursor protein and death receptor 6 function in the same pathway to control axonal pruning independent of β-secretase.
Volume: 34
Issue: 19
Pages: 6438-47
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Publication
29780880 | J:272201
 
First Author: Brown R
Year: 2018
Journal: eNeuro
Title: Circadian and Brain State Modulation of Network Hyperexcitability in Alzheimer's Disease.
Volume: 5
Issue: 2
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Publication
36901941 | J:348623
 
First Author: Sheikh AM
Year: 2023
Journal: Int J Mol Sci
Title: Alzheimer's Amyloid β Peptide Induces Angiogenesis in an Alzheimer's Disease Model Mouse through Placental Growth Factor and Angiopoietin 2 Expressions.
Volume: 24
Issue: 5
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Publication
35697511 | J:334645
 
First Author: Gannon M
Year: 2022
Journal: eNeuro
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