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Category: Publication
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Type Details Score
Publication
31103943 | J:281609
 
First Author: Castano-Prat P
Year: 2019
Journal: Neurobiol Aging
Title: Altered slow (<1 Hz) and fast (beta and gamma) neocortical oscillations in the 3xTg-AD mouse model of Alzheimer's disease under anesthesia.
Volume: 79
Pages: 142-151
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Publication
33771205 | J:360691
First Author: Koh SH
Year: 2021
Journal: Alzheimers Res Ther
Title: Efficacy and safety of GV1001 in patients with moderate-to-severe Alzheimer's disease already receiving donepezil: a phase 2 randomized, double-blind, placebo-controlled, multicenter clinical trial.
Volume: 13
Issue: 1
Pages: 66
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Publication
27105281 | J:350774
First Author: Chu TT
Year: 2016
Journal: Cell Chem Biol
Title: Specific Knockdown of Endogenous Tau Protein by Peptide-Directed Ubiquitin-Proteasome Degradation.
Volume: 23
Issue: 4
Pages: 453-61
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Publication
39225174 | J:360719
First Author: Yu L
Year: 2024
Journal: Phytother Res
Title: Thonningianin A from Penthorum chinense Pursh as a targeted inhibitor of Alzheimer's disease-related β-amyloid and Tau proteins.
Volume: 38
Issue: 9
Pages: 4815-4831
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Publication
23500896 | J:197528
 
First Author: Davis KE
Year: 2013
Journal: Behav Brain Res
Title: Episodic-like memory is sensitive to both Alzheimer's-like pathological accumulation and normal ageing processes in mice.
Volume: 254
Pages: 73-82
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Publication
39532829 | J:360717
     
First Author: Wu CY
Year: 2024
Journal: Geroscience
Title: ACSL3 is a promising therapeutic target for alleviating anxiety and depression in Alzheimer's disease.
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Publication
21918687 | J:176128
First Author: Chen S
Year: 2011
Journal: PLoS One
Title: Allopregnanolone promotes regeneration and reduces β-amyloid burden in a preclinical model of Alzheimer's disease.
Volume: 6
Issue: 8
Pages: e24293
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Publication
34879266 | J:321535
First Author: Han J
Year: 2021
Journal: Cell Rep
Title: Aberrant role of pyruvate kinase M2 in the regulation of gamma-secretase and memory deficits in Alzheimer's disease.
Volume: 37
Issue: 10
Pages: 110102
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Publication
16687509 | J:108684
First Author: Stutzmann GE
Year: 2006
Journal: J Neurosci
Title: Enhanced ryanodine receptor recruitment contributes to Ca2+ disruptions in young, adult, and aged Alzheimer's disease mice.
Volume: 26
Issue: 19
Pages: 5180-9
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Publication
35431906 | J:323889
 
First Author: Carvalho da Silva AM
Year: 2022
Journal: Front Aging Neurosci
Title: Simultaneous Alteration of the Circadian Variation of Memory, Hippocampal Synaptic Plasticity, and Metabolism in a Triple Transgenic Mouse Model of Alzheimer's Disease.
Volume: 14
Pages: 835885
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Publication
19914182 | J:155589
First Author: Zhang YW
Year: 2009
Journal: Neuron
Title: A functional mouse retroposed gene Rps23r1 reduces Alzheimer's beta-amyloid levels and tau phosphorylation.
Volume: 64
Issue: 3
Pages: 328-40
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Publication
37185578 | J:350062
First Author: Noel RL
Year: 2023
Journal: Sci Rep
Title: Natural aging and Alzheimer's disease pathology increase susceptibility to focused ultrasound-induced blood-brain barrier opening.
Volume: 13
Issue: 1
Pages: 6757
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Publication
39448026 | J:360699
 
First Author: Carvalho D
Year: 2025
Journal: J Proteomics
Title: Untargeted metabolomics of 3xTg-AD neurotoxic astrocytes.
Volume: 310
Pages: 105336
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Publication
35961538 | J:328004
 
First Author: Castillo-Mariqueo L
Year: 2022
Journal: Behav Brain Res
Title: Clasping, ledge-score coordination and early gait impairments as primary behavioural markers of functional impairment in Alzheimer's disease.
Volume: 435
Pages: 114054
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Publication
27255814 | J:234996
 
First Author: Vandal M
Year: 2016
Journal: Neurobiol Aging
Title: Impaired thermoregulation and beneficial effects of thermoneutrality in the 3×Tg-AD model of Alzheimer's disease.
Volume: 43
Pages: 47-57
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Publication
31427599 | J:284641
First Author: Park SJ
Year: 2019
Journal: Sci Rep
Title: Visualizing Alzheimer's Disease Mouse Brain with Multispectral Optoacoustic Tomography using a Fluorescent probe, CDnir7.
Volume: 9
Issue: 1
Pages: 12052
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Publication
25093460 | J:215753
First Author: Xu J
Year: 2014
Journal: PLoS Biol
Title: Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease.
Volume: 12
Issue: 8
Pages: e1001923
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Publication
19561098 | J:151661
First Author: Fonseca MI
Year: 2009
Journal: J Immunol
Title: Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease.
Volume: 183
Issue: 2
Pages: 1375-83
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Publication
27103531 | J:235027
 
First Author: Moreno-Castilla P
Year: 2016
Journal: Neurobiol Aging
Title: Dopaminergic neurotransmission dysfunction induced by amyloid-β transforms cortical long-term potentiation into long-term depression and produces memory impairment.
Volume: 41
Pages: 187-199
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Publication
20505094 | J:160821
First Author: Clinton LK
Year: 2010
Journal: J Neurosci
Title: Synergistic Interactions between Abeta, tau, and alpha-synuclein: acceleration of neuropathology and cognitive decline.
Volume: 30
Issue: 21
Pages: 7281-9
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Publication
24244584 | J:209696
First Author: Ding F
Year: 2013
Journal: PLoS One
Title: Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic intervention.
Volume: 8
Issue: 11
Pages: e79977
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Publication
23683389 | J:284655
First Author: Giannopoulos PF
Year: 2013
Journal: Biol Psychiatry
Title: 5-lipoxygenase activating protein reduction ameliorates cognitive deficit, synaptic dysfunction, and neuropathology in a mouse model of Alzheimer's disease.
Volume: 74
Issue: 5
Pages: 348-56
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Publication
25731615 | J:221193
First Author: Kamphuis W
Year: 2015
Journal: Glia
Title: GFAP and vimentin deficiency alters gene expression in astrocytes and microglia in wild-type mice and changes the transcriptional response of reactive glia in mouse model for Alzheimer's disease.
Volume: 63
Issue: 6
Pages: 1036-56
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Publication
25253847 | J:216611
First Author: Liu Y
Year: 2014
Journal: J Neurosci
Title: IKKβ deficiency in myeloid cells ameliorates Alzheimer's disease-related symptoms and pathology.
Volume: 34
Issue: 39
Pages: 12982-99
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Publication
32579923 | J:298885
First Author: Socodato R
Year: 2020
Journal: Cell Rep
Title: Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration.
Volume: 31
Issue: 12
Pages: 107796
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Publication
23831297 | J:200093
First Author: Yang Y
Year: 2013
Journal: Am J Pathol
Title: APOE3, but not APOE4, bone marrow transplantation mitigates behavioral and pathological changes in a mouse model of Alzheimer disease.
Volume: 183
Issue: 3
Pages: 905-17
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Publication
39657671 | J:361249
First Author: Matera A
Year: 2025
Journal: Immunity
Title: Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus.
Volume: 58
Issue: 1
Pages: 197-217.e13
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Publication
28869476 | J:272696
First Author: Javidnia M
Year: 2017
Journal: J Alzheimers Dis
Title: Pazopanib Reduces Phosphorylated Tau Levels and Alters Astrocytes in a Mouse Model of Tauopathy.
Volume: 60
Issue: 2
Pages: 461-481
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Publication
32508844 | J:305735
 
First Author: Joly-Amado A
Year: 2020
Journal: Front Immunol
Title: CCL2 Overexpression in the Brain Promotes Glial Activation and Accelerates Tau Pathology in a Mouse Model of Tauopathy.
Volume: 11
Pages: 997
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Publication
14642273 | J:104240
First Author: Cruz JC
Year: 2003
Journal: Neuron
Title: Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles.
Volume: 40
Issue: 3
Pages: 471-83
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Publication
36536457 | J:338954
First Author: Kim DW
Year: 2022
Journal: Mol Neurodegener
Title: Amyloid-beta and tau pathologies act synergistically to induce novel disease stage-specific microglia subtypes.
Volume: 17
Issue: 1
Pages: 83
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Publication
23884929 | J:199798
First Author: Cheng N
Year: 2013
Journal: J Neurosci
Title: Olfactory functions scale with circuit restoration in a rapidly reversible Alzheimer's disease model.
Volume: 33
Issue: 30
Pages: 12208-17
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Publication
23636056 | J:204766
First Author: Sandy AR
Year: 2013
Journal: J Immunol
Title: T cell-specific notch inhibition blocks graft-versus-host disease by inducing a hyporesponsive program in alloreactive CD4+ and CD8+ T cells.
Volume: 190
Issue: 11
Pages: 5818-28
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Publication
31727829 | J:281685
First Author: Zhu PJ
Year: 2019
Journal: Science
Title: Activation of the ISR mediates the behavioral and neurophysiological abnormalities in Down syndrome.
Volume: 366
Issue: 6467
Pages: 843-849
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Publication
21712989 | J:288163
First Author: Takeuchi H
Year: 2011
Journal: PLoS One
Title: Blockade of gap junction hemichannel suppresses disease progression in mouse models of amyotrophic lateral sclerosis and Alzheimer's disease.
Volume: 6
Issue: 6
Pages: e21108
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Publication
18463254 | J:135174
First Author: Meilandt WJ
Year: 2008
Journal: J Neurosci
Title: Enkephalin elevations contribute to neuronal and behavioral impairments in a transgenic mouse model of Alzheimer's disease.
Volume: 28
Issue: 19
Pages: 5007-17
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Publication
32778161 | J:353258
First Author: Farmer KM
Year: 2020
Journal: Acta Neuropathol Commun
Title: P53 aggregation, interactions with tau, and impaired DNA damage response in Alzheimer's disease.
Volume: 8
Issue: 1
Pages: 132
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Publication
22836259 | J:186543
First Author: Larson ME
Year: 2012
Journal: J Neurosci
Title: Soluble α-synuclein is a novel modulator of Alzheimer's disease pathophysiology.
Volume: 32
Issue: 30
Pages: 10253-66
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Publication
29162816 | J:256308
First Author: Zhu H
Year: 2017
Journal: Nat Commun
Title: Impairments of spatial memory in an Alzheimer's disease model via degeneration of hippocampal cholinergic synapses.
Volume: 8
Issue: 1
Pages: 1676
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Publication
37714307 | J:341241
 
First Author: Lisgaras CP
Year: 2023
Journal: Neurobiol Dis
Title: Interictal spikes in Alzheimer's disease: Preclinical evidence for dominance of the dentate gyrus and cholinergic control by the medial septum.
Volume: 187
Pages: 106294
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Publication
22323736 | J:181688
First Author: Cramer PE
Year: 2012
Journal: Science
Title: ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models.
Volume: 335
Issue: 6075
Pages: 1503-6
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Publication
17234594 | J:117413
First Author: Kim J
Year: 2007
Journal: J Neurosci
Title: Abeta40 inhibits amyloid deposition in vivo.
Volume: 27
Issue: 3
Pages: 627-33
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Publication
33482356 | J:307763
 
First Author: Marquez A
Year: 2021
Journal: Neurobiol Dis
Title: Tau associated peripheral and central neurodegeneration: Identification of an early imaging marker for tauopathy.
Volume: 151
Pages: 105273
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Publication
30617325 | J:295032
First Author: Lourenco MV
Year: 2019
Journal: Nat Med
Title: Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models.
Volume: 25
Issue: 1
Pages: 165-175
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Publication
22293606 | J:182294
First Author: Guedj F
Year: 2012
Journal: Neurobiol Dis
Title: DYRK1A: a master regulatory protein controlling brain growth.
Volume: 46
Issue: 1
Pages: 190-203
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Publication
23512985 | J:198546
First Author: Laguna A
Year: 2013
Journal: Hum Mol Genet
Title: Triplication of DYRK1A causes retinal structural and functional alterations in Down syndrome.
Volume: 22
Issue: 14
Pages: 2775-84
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Publication
32783810 | J:298653
   
First Author: Zorrilla de San Martin J
Year: 2020
Journal: Elife
Title: Alterations of specific cortical GABAergic circuits underlie abnormal network activity in a mouse model of Down syndrome.
Volume: 9
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Publication
35780436 | J:345459
First Author: Deng Y
Year: 2022
Journal: Acta Neuropathol
Title: Loss of LAMP5 interneurons drives neuronal network dysfunction in Alzheimer's disease.
Volume: 144
Issue: 4
Pages: 637-650
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Publication
25706990 | J:226301
First Author: Brendel M
Year: 2015
Journal: PLoS One
Title: Cross-sectional comparison of small animal [18F]-florbetaben amyloid-PET between transgenic AD mouse models.
Volume: 10
Issue: 2
Pages: e0116678
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Publication
20864679 | J:166257
First Author: Lee S
Year: 2010
Journal: Am J Pathol
Title: CX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer's disease mouse models.
Volume: 177
Issue: 5
Pages: 2549-62
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Publication
20813165 | J:169720
First Author: Mei X
Year: 2010
Journal: Neuroscience
Title: Astroglial connexin immunoreactivity is specifically altered at β-amyloid plaques in β-amyloid precursor protein/presenilin1 mice.
Volume: 171
Issue: 1
Pages: 92-105
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Publication
22522613 | J:196823
First Author: Zhang Y
Year: 2012
Journal: Diabetes
Title: Amyloid-β induces hepatic insulin resistance by activating JAK2/STAT3/SOCS-1 signaling pathway.
Volume: 61
Issue: 6
Pages: 1434-43
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Publication
19720431 | J:173732
First Author: Montgomery KS
Year: 2011
Journal: Neurobiol Aging
Title: Novel age-dependent learning deficits in a mouse model of Alzheimer's disease: implications for translational research.
Volume: 32
Issue: 7
Pages: 1273-85
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Publication
32079659 | J:290161
 
First Author: Oudart M
Year: 2020
Journal: J Cell Sci
Title: AstroDot - a new method for studying the spatial distribution of mRNA in astrocytes.
Volume: 133
Issue: 7
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Publication
32601313 | J:296369
First Author: Henjum K
Year: 2020
Journal: Sci Rep
Title: Analyzing microglial-associated Aβ in Alzheimer's disease transgenic mice with a novel mid-domain Aβ-antibody.
Volume: 10
Issue: 1
Pages: 10590
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Publication
29346778 | J:324542
First Author: Friedman BA
Year: 2018
Journal: Cell Rep
Title: Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer's Disease Not Evident in Mouse Models.
Volume: 22
Issue: 3
Pages: 832-847
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Publication
21951279 | J:178473
First Author: Jung CK
Year: 2011
Journal: J Neurochem
Title: Role of presenilin 1 in structural plasticity of cortical dendritic spines in vivo.
Volume: 119
Issue: 5
Pages: 1064-73
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Publication
19228952 | J:146594
First Author: Meilandt WJ
Year: 2009
Journal: J Neurosci
Title: Neprilysin overexpression inhibits plaque formation but fails to reduce pathogenic Abeta oligomers and associated cognitive deficits in human amyloid precursor protein transgenic mice.
Volume: 29
Issue: 7
Pages: 1977-86
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Publication
27029737 | J:242434
First Author: Li H
Year: 2016
Journal: Genetics
Title: Penetrance of Congenital Heart Disease in a Mouse Model of Down Syndrome Depends on a Trisomic Potentiator of a Disomic Modifier.
Volume: 203
Issue: 2
Pages: 763-70
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17897742 | J:128743
First Author: Rachidi M
Year: 2007
Journal: Neurosci Res
Title: Mental retardation in Down syndrome: from gene dosage imbalance to molecular and cellular mechanisms.
Volume: 59
Issue: 4
Pages: 349-69
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Publication
19297404 | J:156661
First Author: Wiseman FK
Year: 2009
Journal: Hum Mol Genet
Title: Down syndrome--recent progress and future prospects.
Volume: 18
Issue: R1
Pages: R75-83
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Publication
17050550 | J:117029
First Author: Davisson M
Year: 2007
Journal: Hum Reprod
Title: Impact of trisomy on fertility and meiosis in male mice.
Volume: 22
Issue: 2
Pages: 468-76
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Publication
18629032 | J:208905
First Author: Forejt J
Year: 2003
Journal: Comp Funct Genomics
Title: Segmental trisomy of mouse chromosome 17: introducing an alternative model of Down's syndrome.
Volume: 4
Issue: 6
Pages: 647-52
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Publication
24801365 | J:214001
 
First Author: Souchet B
Year: 2014
Journal: Neurobiol Dis
Title: Excitation/inhibition balance and learning are modified by Dyrk1a gene dosage.
Volume: 69
Pages: 65-75
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Publication
20231476 | J:158919
First Author: Heneka MT
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine.
Volume: 107
Issue: 13
Pages: 6058-63
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Publication
30040874 | J:272683
     
First Author: Granger MW
Year: 2018
Journal: J Neurochem
Title: Distinct disruptions in Land's cycle remodeling of glycerophosphocholines in murine cortex mark symptomatic onset and progression in two Alzheimer's disease mouse models.
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Publication
21695208 | J:174789
First Author: Butler D
Year: 2011
Journal: PLoS One
Title: Protective effects of positive lysosomal modulation in Alzheimer's disease transgenic mouse models.
Volume: 6
Issue: 6
Pages: e20501
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Publication
8894693 | J:35780
First Author: Bressler SL
Year: 1996
Journal: Hum Mol Genet
Title: cDNA cloning and chromosome mapping of the human Fe65 gene: interaction of the conserved cytoplasmic domains of the human beta-amyloid precursor protein and its homologues with the mouse Fe65 protein.
Volume: 5
Issue: 10
Pages: 1589-98
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26868295 | J:246319
First Author: Goldsworthy M
Year: 2016
Journal: Diabetes
Title: Haploinsufficiency of the Insulin Receptor in the Presence of a Splice-Site Mutation in Ppp2r2a Results in a Novel Digenic Mouse Model of Type 2 Diabetes.
Volume: 65
Issue: 5
Pages: 1434-46
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11549720 | J:71536
First Author: Cowan CM
Year: 2001
Journal: J Neurosci
Title: Caspases 3 and 9 send a pro-apoptotic signal from synapse to cell body in olfactory receptor neurons.
Volume: 21
Issue: 18
Pages: 7099-109
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Publication
23418567 | J:197198
First Author: Garringer HJ
Year: 2013
Journal: PLoS One
Title: Increased tau phosphorylation and tau truncation, and decreased synaptophysin levels in mutant BRI2/tau transgenic mice.
Volume: 8
Issue: 2
Pages: e56426
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12082633 | J:76678
First Author: Fleischer A
Year: 2002
Journal: Oncogene
Title: Proapoptotic activity of ITM2B(s), a BH3-only protein induced upon IL-2-deprivation which interacts with Bcl-2.
Volume: 21
Issue: 20
Pages: 3181-9
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33027640 | J:300542
First Author: Pinto B
Year: 2020
Journal: Neuron
Title: Rescuing Over-activated Microglia Restores Cognitive Performance in Juvenile Animals of the Dp(16) Mouse Model of Down Syndrome.
Volume: 108
Issue: 5
Pages: 887-904.e12
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27195491 | J:231889
First Author: Peiris H
Year: 2016
Journal: PLoS Genet
Title: A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes.
Volume: 12
Issue: 5
Pages: e1006033
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21835156 | J:176301
First Author: Montgomery SL
Year: 2011
Journal: Am J Pathol
Title: Ablation of TNF-RI/RII expression in Alzheimer's disease mice leads to an unexpected enhancement of pathology: implications for chronic pan-TNF-α suppressive therapeutic strategies in the brain.
Volume: 179
Issue: 4
Pages: 2053-70
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25339759 | J:217151
First Author: Shibuya Y
Year: 2014
Journal: J Neurosci
Title: Inhibiting ACAT1/SOAT1 in microglia stimulates autophagy-mediated lysosomal proteolysis and increases Aβ1-42 clearance.
Volume: 34
Issue: 43
Pages: 14484-501
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20133765 | J:157545
First Author: Bryleva EY
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD.
Volume: 107
Issue: 7
Pages: 3081-6
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26872418 | J:281483
 
First Author: Ferretti MT
Year: 2016
Journal: Brain Behav Immun
Title: T-cell brain infiltration and immature antigen-presenting cells in transgenic models of Alzheimer's disease-like cerebral amyloidosis.
Volume: 54
Pages: 211-225
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Publication
31004063 | J:274643
First Author: Xiang J
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Delta-secretase-cleaved Tau antagonizes TrkB neurotrophic signalings, mediating Alzheimer's disease pathologies.
Volume: 116
Issue: 18
Pages: 9094-9102
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Publication
38906984 | J:350176
First Author: Jong Huat T
Year: 2024
Journal: Sci Rep
Title: The impact of astrocytic NF-κB on healthy and Alzheimer's disease brains.
Volume: 14
Issue: 1
Pages: 14305
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Publication
30850634 | J:275633
First Author: Caberlotto L
Year: 2019
Journal: Sci Rep
Title: Cross-disease analysis of Alzheimer's disease and type-2 Diabetes highlights the role of autophagy in the pathophysiology of two highly comorbid diseases.
Volume: 9
Issue: 1
Pages: 3965
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Publication
18021291 | J:141555
First Author: Lopez JR
Year: 2008
Journal: J Neurochem
Title: Increased intraneuronal resting [Ca2+] in adult Alzheimer's disease mice.
Volume: 105
Issue: 1
Pages: 262-71
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Publication
38555992 | J:351247
 
First Author: Wang J
Year: 2024
Journal: Brain Behav Immun
Title: A TrkB cleavage fragment in hippocampus promotes Depressive-Like behavior in mice.
Volume: 119
Pages: 56-83
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21704011 | J:174403
First Author: Medeiros R
Year: 2011
Journal: Am J Pathol
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