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Type Details Score
Publication
27511009 | J:317109
First Author: Hefter D
Year: 2016
Journal: J Neurosci
Title: Amyloid Precursor Protein Protects Neuronal Network Function after Hypoxia via Control of Voltage-Gated Calcium Channels.
Volume: 36
Issue: 32
Pages: 8356-71
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Publication
27474225 | J:238237
 
First Author: Wu K
Year: 2016
Journal: Neuroscience
Title: Enriched endogenous n-3 polyunsaturated fatty acids alleviate cognitive and behavioral deficits in a mice model of Alzheimer's disease.
Volume: 333
Pages: 345-55
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Publication
37580462 | J:347261
First Author: Naganuma F
Year: 2023
Journal: Mol Imaging Biol
Title: A Novel Near-Infrared Fluorescence Probe THK-565 Enables In Vivo Detection of Amyloid Deposits in Alzheimer's Disease Mouse Model.
Volume: 25
Issue: 6
Pages: 1115-1124
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Publication
10681074 | J:60462
First Author: Emilien G
Year: 2000
Journal: Arch Neurol
Title: Alzheimer disease: mouse models pave the way for therapeutic opportunities.
Volume: 57
Issue: 2
Pages: 176-81
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Publication
7929050 | J:20533
First Author: Zaidi SH
Year: 1994
Journal: J Biol Chem
Title: Multiple proteins interact at a unique cis-element in the 3'-untranslated region of amyloid precursor protein mRNA.
Volume: 269
Issue: 39
Pages: 24000-6
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Publication
9126173 | J:39386
First Author: Volloch V
Year: 1997
Journal: Exp Neurol
Title: Possible mechanism for resistance to Alzheimer's disease (AD) in mice suggests a new approach to generate a mouse model for sporadic AD and may explain familial resistance to AD in man.
Volume: 144
Issue: 1
Pages: 214-8
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Publication
31649526 | J:310131
 
First Author: Haytural H
Year: 2019
Journal: Front Aging Neurosci
Title: Non-specific Detection of a Major Western Blotting Band in Human Brain Homogenates by a Multitude of Amyloid Precursor Protein Antibodies.
Volume: 11
Pages: 273
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Publication
19215301 | J:147883
First Author: Lord A
Year: 2009
Journal: FEBS J
Title: Amyloid-beta protofibril levels correlate with spatial learning in Arctic Alzheimer's disease transgenic mice.
Volume: 276
Issue: 4
Pages: 995-1006
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Publication
11279122 | J:69967
First Author: Chishti MA
Year: 2001
Journal: J Biol Chem
Title: Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.
Volume: 276
Issue: 24
Pages: 21562-70
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Publication
19779148 | J:154074
First Author: Kang JE
Year: 2009
Journal: Science
Title: Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle.
Volume: 326
Issue: 5955
Pages: 1005-7
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Publication
25073087 | J:218336
 
First Author: Köhler C
Year: 2014
Journal: Neurobiol Dis
Title: Granulovacuolar degeneration and unfolded protein response in mouse models of tauopathy and Aβ amyloidosis.
Volume: 71
Pages: 169-79
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Publication
23294633 | J:203370
First Author: Köhler C
Year: 2013
Journal: Neurobiol Aging
Title: Active glycogen synthase kinase-3 and tau pathology-related tyrosine phosphorylation in pR5 human tau transgenic mice.
Volume: 34
Issue: 5
Pages: 1369-79
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Publication
34299071 | J:324395
 
First Author: Kaur H
Year: 2021
Journal: Int J Mol Sci
Title: Liver Bile Acid Changes in Mouse Models of Alzheimer's Disease.
Volume: 22
Issue: 14
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Publication
19435805 | J:150584
First Author: Liu ML
Year: 2009
Journal: J Cell Sci
Title: Omi is a mammalian heat-shock protein that selectively binds and detoxifies oligomeric amyloid-beta.
Volume: 122
Issue: Pt 11
Pages: 1917-26
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Publication
11359882 | J:69528
First Author: Han X
Year: 2001
Journal: J Neurochem
Title: Plasmalogen deficiency in early Alzheimer's disease subjects and in animal models: molecular characterization using electrospray ionization mass spectrometry.
Volume: 77
Issue: 4
Pages: 1168-80
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Publication
12808450 | J:268022
First Author: Deane R
Year: 2003
Journal: Nat Med
Title: RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain.
Volume: 9
Issue: 7
Pages: 907-13
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Publication
11572944 | J:72239
First Author: Masliah E
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease.
Volume: 98
Issue: 21
Pages: 12245-50
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Publication
10611368 | J:59078
First Author: Bales KR
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease.
Volume: 96
Issue: 26
Pages: 15233-8
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Publication
9354781 | J:43845
First Author: Bales KR
Year: 1997
Journal: Nat Genet
Title: Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.
Volume: 17
Issue: 3
Pages: 263-4
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Publication
23563578 | J:197603
First Author: Dolev I
Year: 2013
Journal: Nat Neurosci
Title: Spike bursts increase amyloid-β 40/42 ratio by inducing a presenilin-1 conformational change.
Volume: 16
Issue: 5
Pages: 587-95
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Publication
19077180 | J:142183
First Author: Filali M
Year: 2009
Journal: Genes Brain Behav
Title: Cognitive and non-cognitive behaviors in an APPswe/PS1 bigenic model of Alzheimer's disease.
Volume: 8
Issue: 2
Pages: 143-8
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Publication
19897719 | J:154750
First Author: Rhein V
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice.
Volume: 106
Issue: 47
Pages: 20057-62
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Publication
22782894 | J:190417
First Author: Rama N
Year: 2012
Journal: J Biol Chem
Title: Amyloid precursor protein regulates netrin-1-mediated commissural axon outgrowth.
Volume: 287
Issue: 35
Pages: 30014-23
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Publication
37327344 | J:336924
First Author: Shabani K
Year: 2023
Journal: Sci Adv
Title: The temporal balance between self-renewal and differentiation of human neural stem cells requires the amyloid precursor protein.
Volume: 9
Issue: 24
Pages: eadd5002
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Publication
17121854 | J:118164
First Author: Minopoli G
Year: 2007
Journal: J Biol Chem
Title: Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage.
Volume: 282
Issue: 2
Pages: 831-5
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Publication
21795536 | J:174507
First Author: Ranganathan S
Year: 2011
Journal: J Neurosci
Title: LRAD3, a novel low-density lipoprotein receptor family member that modulates amyloid precursor protein trafficking.
Volume: 31
Issue: 30
Pages: 10836-46
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Publication
8287193 | J:16255
First Author: Solà C
Year: 1993
Journal: Eur J Neurosci
Title: Regional distribution of amyloid beta-protein precursor, growth-associated phosphoprotein-43 and microtubule-associated protein 2 messenger RNAs in the nigrostriatal system of normal and Weaver mutant mice and effects of ventral mesencephalic grafts.
Volume: 5
Issue: 11
Pages: 1442-54
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Publication
19058878 | J:165242
First Author: Austin SA
Year: 2010
Journal: Neurobiol Aging
Title: Amyloid precursor protein mediates monocyte adhesion in AD tissue and apoE(-)/(-) mice.
Volume: 31
Issue: 11
Pages: 1854-66
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Publication
22046307 | J:178076
First Author: Westmark CJ
Year: 2011
Journal: PLoS One
Title: Reversal of fragile X phenotypes by manipulation of AβPP/Aβ levels in Fmr1KO mice.
Volume: 6
Issue: 10
Pages: e26549
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Publication
19164281 | J:148737
First Author: Hoe HS
Year: 2009
Journal: J Biol Chem
Title: The effects of amyloid precursor protein on postsynaptic composition and activity.
Volume: 284
Issue: 13
Pages: 8495-506
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Publication
20016080 | J:157106
First Author: Yang L
Year: 2009
Journal: J Neurosci
Title: Amyloid precursor protein regulates Cav1.2 L-type calcium channel levels and function to influence GABAergic short-term plasticity.
Volume: 29
Issue: 50
Pages: 15660-8
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Publication
25767117 | J:222586
First Author: Liu C
Year: 2015
Journal: J Biol Chem
Title: Amyloid precursor protein enhances Nav1.6 sodium channel cell surface expression.
Volume: 290
Issue: 19
Pages: 12048-57
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Publication
31273083 | J:280392
First Author: Saito T
Year: 2019
Journal: J Biol Chem
Title: Humanization of the entire murine Mapt gene provides a murine model of pathological human tau propagation.
Volume: 294
Issue: 34
Pages: 12754-12765
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Publication
23863834 | J:213474
First Author: Maia LF
Year: 2013
Journal: Sci Transl Med
Title: Changes in amyloid-β and Tau in the cerebrospinal fluid of transgenic mice overexpressing amyloid precursor protein.
Volume: 5
Issue: 194
Pages: 194re2
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Publication
18762245 | J:141188
First Author: Abdul HM
Year: 2008
Journal: Free Radic Biol Med
Title: Oxidative damage in brain from human mutant APP/PS-1 double knock-in mice as a function of age.
Volume: 45
Issue: 10
Pages: 1420-5
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Publication
17070803 | J:141506
First Author: Zhang C
Year: 2007
Journal: Exp Neurol
Title: Long-lasting impairment in hippocampal neurogenesis associated with amyloid deposition in a knock-in mouse model of familial Alzheimer's disease.
Volume: 204
Issue: 1
Pages: 77-87
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Publication
23704887 | J:270976
First Author: Yang M
Year: 2013
Journal: PLoS One
Title: The intracellular domain of sortilin interacts with amyloid precursor protein and regulates its lysosomal and lipid raft trafficking.
Volume: 8
Issue: 5
Pages: e63049
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Publication
29056359 | J:262115
First Author: Ruan CS
Year: 2018
Journal: Exp Neurol
Title: Sortilin inhibits amyloid pathology by regulating non-specific degradation of APP.
Volume: 299
Issue: Pt A
Pages: 75-85
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Publication
21062284 | J:167625
First Author: Smith P
Year: 2011
Journal: J Neurochem
Title: In vivo regulation of amyloid precursor protein neuronal splicing by microRNAs.
Volume: 116
Issue: 2
Pages: 240-7
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Publication
28646018 | J:256414
First Author: Zhang F
Year: 2017
Journal: FASEB J
Title: The amyloid precursor protein modulates α2A-adrenergic receptor endocytosis and signaling through disrupting arrestin 3 recruitment.
Volume: 31
Issue: 10
Pages: 4434-4446
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Publication
34329683 | J:312987
First Author: Sato K
Year: 2021
Journal: J Biol Chem
Title: A third-generation mouse model of Alzheimer's disease shows early and increased cored plaque pathology composed of wild-type human amyloid β peptide.
Volume: 297
Issue: 3
Pages: 101004
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9535056 | J:46769
First Author: Apert C
Year: 1998
Journal: J Neuroendocrinol
Title: Profiles of amyloid precursor and presenilin 2-like proteins are correlated during development of the mouse hypothalamus.
Volume: 10
Issue: 2
Pages: 101-9
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Publication
20497468 | J:163792
First Author: Tummala H
Year: 2010
Journal: Eur J Neurosci
Title: Interaction of a novel mitochondrial protein, 4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (NIPSNAP1), with the amyloid precursor protein family.
Volume: 31
Issue: 11
Pages: 1926-34
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Publication
20925061 | J:182473
First Author: Steuble M
Year: 2010
Journal: Proteomics
Title: Molecular characterization of a trafficking organelle: dissecting the axonal paths of calsyntenin-1 transport vesicles.
Volume: 10
Issue: 21
Pages: 3775-88
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Publication
17855370 | J:128398
First Author: Wiley JC
Year: 2007
Journal: J Biol Chem
Title: Fe65 stimulates proteolytic liberation of the beta-amyloid precursor protein intracellular domain.
Volume: 282
Issue: 46
Pages: 33313-25
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Publication
18468999 | J:138111
First Author: Nakaya T
Year: 2008
Journal: J Biol Chem
Title: Regulation of FE65 nuclear translocation and function by amyloid beta-protein precursor in osmotically stressed cells.
Volume: 283
Issue: 27
Pages: 19119-31
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Publication
30614363 | J:327451
First Author: Austin SA
Year: 2020
Journal: J Cereb Blood Flow Metab
Title: Partial loss of endothelial nitric oxide leads to increased cerebrovascular beta amyloid.
Volume: 40
Issue: 2
Pages: 392-403
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Publication
25017047 | J:311709
 
First Author: Shi C
Year: 2014
Journal: J Steroid Biochem Mol Biol
Title: Estrogen receptor α promotes non-amyloidogenic processing of platelet amyloid precursor protein via the MAPK/ERK pathway.
Volume: 144 Pt B
Pages: 280-5
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Publication
21081501 | J:168499
First Author: Delarasse C
Year: 2011
Journal: J Biol Chem
Title: The purinergic receptor P2X7 triggers alpha-secretase-dependent processing of the amyloid precursor protein.
Volume: 286
Issue: 4
Pages: 2596-606
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Publication
37211092 | J:337947
First Author: Sawmiller D
Year: 2023
Journal: J Biol Chem
Title: Targeting apolipoprotein E and N-terminal amyloid β-protein precursor interaction improves cognition and reduces amyloid pathology in Alzheimer's mice.
Volume: 299
Issue: 7
Pages: 104846
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Publication
37857162 | J:342399
 
First Author: Takebayashi Y
Year: 2023
Journal: Biochem Biophys Res Commun
Title: Apolipoprotein E genotype-dependent accumulation of amyloid β in APP-knock-in mouse model of Alzheimer's disease.
Volume: 683
Pages: 149106
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Publication
32093427 | J:297987
 
First Author: Viana GM
Year: 2020
Journal: Int J Mol Sci
Title: Cathepsin B-associated Activation of Amyloidogenic Pathway in Murine Mucopolysaccharidosis Type I Brain Cortex.
Volume: 21
Issue: 4
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16478525 | J:106153
First Author: Mohmmad Abdul H
Year: 2006
Journal: J Neurochem
Title: Mutations in amyloid precursor protein and presenilin-1 genes increase the basal oxidative stress in murine neuronal cells and lead to increased sensitivity to oxidative stress mediated by amyloid beta-peptide (1-42), HO and kainic acid: implications for Alzheimer's disease.
Volume: 96
Issue: 5
Pages: 1322-35
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22361682 | J:204630
First Author: Woo JA
Year: 2012
Journal: Cell Death Differ
Title: Pivotal role of the RanBP9-cofilin pathway in Aβ-induced apoptosis and neurodegeneration.
Volume: 19
Issue: 9
Pages: 1413-23
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Publication
25150572 | J:218312
First Author: Xu Y
Year: 2015
Journal: Neurobiol Aging
Title: Beta amyloid-induced upregulation of death receptor 6 accelerates the toxic effect of N-terminal fragment of amyloid precursor protein.
Volume: 36
Issue: 1
Pages: 157-68
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Publication
25404298 | J:216651
First Author: Chen Y
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: α(2A) adrenergic receptor promotes amyloidogenesis through disrupting APP-SorLA interaction.
Volume: 111
Issue: 48
Pages: 17296-301
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Publication
24465508 | J:212342
First Author: Bitsikas V
Year: 2014
Journal: PLoS One
Title: The role of flotillins in regulating aβ production, investigated using flotillin 1-/-, flotillin 2-/- double knockout mice.
Volume: 9
Issue: 1
Pages: e85217
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Publication
24398293 | J:312211
First Author: Dumont M
Year: 2014
Journal: FASEB J
Title: PGC-1α overexpression exacerbates β-amyloid and tau deposition in a transgenic mouse model of Alzheimer's disease.
Volume: 28
Issue: 4
Pages: 1745-55
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Publication
21368882 | J:277859
 
First Author: Lee MH
Year: 2010
Journal: Cell Death Dis
Title: TGF-β induces TIAF1 self-aggregation via type II receptor-independent signaling that leads to generation of amyloid β plaques in Alzheimer's disease.
Volume: 1
Pages: e110
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15601849 | J:95389
First Author: Lambourne SL
Year: 2005
Journal: Mol Cell Biol
Title: Increased tau phosphorylation on mitogen-activated protein kinase consensus sites and cognitive decline in transgenic models for Alzheimer's disease and FTDP-17: evidence for distinct molecular processes underlying tau abnormalities.
Volume: 25
Issue: 1
Pages: 278-93
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Publication
22302812 | J:181344
First Author: Deyts C
Year: 2012
Journal: J Neurosci
Title: Novel GαS-protein signaling associated with membrane-tethered amyloid precursor protein intracellular domain.
Volume: 32
Issue: 5
Pages: 1714-29
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Publication
22992957 | J:189003
First Author: Rice HC
Year: 2012
Journal: Development
Title: Pancortins interact with amyloid precursor protein and modulate cortical cell migration.
Volume: 139
Issue: 21
Pages: 3986-96
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37156643 | J:358882
First Author: Xiong G
Year: 2023
Journal: Brain Pathol
Title: Detection and verification of neurodegeneration after traumatic brain injury in the mouse: Immunohistochemical staining for amyloid precursor protein.
Volume: 33
Issue: 6
Pages: e13163
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Publication
34970419 | J:324402
 
First Author: Mizuno Y
Year: 2021
Journal: Oxid Med Cell Longev
Title: MUTYH Actively Contributes to Microglial Activation and Impaired Neurogenesis in the Pathogenesis of Alzheimer's Disease.
Volume: 2021
Pages: 8635088
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Publication
11532247 | J:72236
First Author: Lüth HJ
Year: 2001
Journal: Brain Res
Title: Expression of endothelial and inducible NOS-isoforms is increased in Alzheimer's disease, in APP23 transgenic mice and after experimental brain lesion in rat: evidence for an induction by amyloid pathology.
Volume: 913
Issue: 1
Pages: 57-67
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Publication
33076948 | J:303244
First Author: Serneels L
Year: 2020
Journal: Mol Neurodegener
Title: Modeling the β-secretase cleavage site and humanizing amyloid-beta precursor protein in rat and mouse to study Alzheimer's disease.
Volume: 15
Issue: 1
Pages: 60
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Publication
34266459 | J:324400
First Author: Benitez DP
Year: 2021
Journal: Mol Neurodegener
Title: Knock-in models related to Alzheimer's disease: synaptic transmission, plaques and the role of microglia.
Volume: 16
Issue: 1
Pages: 47
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Publication
35843448 | J:334649
 
First Author: Ye Q
Year: 2022
Journal: Neurobiol Dis
Title: Hippocampal neural circuit connectivity alterations in an Alzheimer's disease mouse model revealed by monosynaptic rabies virus tracing.
Volume: 172
Pages: 105820
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Publication
19726636 | J:152457
First Author: Wang Z
Year: 2009
Journal: J Neurosci
Title: Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis.
Volume: 29
Issue: 35
Pages: 10788-801
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Publication
17934213 | J:143818
First Author: Bai Y
Year: 2008
Journal: Mol Cell Proteomics
Title: The in vivo brain interactome of the amyloid precursor protein.
Volume: 7
Issue: 1
Pages: 15-34
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Publication
8115398 | J:30229
 
First Author: Davisson MT
Year: 1993
Journal: Prog Clin Biol Res
Title: Segmental trisomy as a mouse model for Down syndrome.
Volume: 384
Pages: 117-33
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Publication
7550346 | J:29232
First Author: Reeves RH
Year: 1995
Journal: Nat Genet
Title: A mouse model for Down syndrome exhibits learning and behaviour deficits.
Volume: 11
Issue: 2
Pages: 177-84
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38735056 | J:351102
First Author: Kotredes KP
Year: 2024
Journal: Alzheimers Dement
Title: Characterizing molecular and synaptic signatures in mouse models of late-onset Alzheimer's disease independent of amyloid and tau pathology.
Volume: 20
Issue: 6
Pages: 4126-4146
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Publication
31177033 | J:351561
 
First Author: Chen Y
Year: 2019
Journal: J Neuroimmunol
Title: Oxymatrine can attenuate pathological deficits of Alzheimer's disease mice through regulation of neuroinflammation.
Volume: 334
Pages: 576978
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Publication
16018997 | J:102734
First Author: Yang J
Year: 2005
Journal: Exp Cell Res
Title: The ciliary rootlet interacts with kinesin light chains and may provide a scaffold for kinesin-1 vesicular cargos.
Volume: 309
Issue: 2
Pages: 379-89
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Publication
12826668 | J:85533
First Author: Yun M
Year: 2003
Journal: J Biol Chem
Title: Crystal structures of the Dab homology domains of mouse disabled 1 and 2.
Volume: 278
Issue: 38
Pages: 36572-81
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Publication
18089558 | J:134018
First Author: Hoe HS
Year: 2008
Journal: J Biol Chem
Title: Fyn modulation of Dab1 effects on amyloid precursor protein and ApoE receptor 2 processing.
Volume: 283
Issue: 10
Pages: 6288-99
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Publication
20864542 | J:167334
First Author: Boland B
Year: 2010
Journal: J Biol Chem
Title: Macroautophagy is not directly involved in the metabolism of amyloid precursor protein.
Volume: 285
Issue: 48
Pages: 37415-26
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Publication
22582169 | J:184761
First Author: Szpankowski L
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Subpixel colocalization reveals amyloid precursor protein-dependent kinesin-1 and dynein association with axonal vesicles.
Volume: 109
Issue: 22
Pages: 8582-7
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Publication
19282473 | J:147140
First Author: Stante M
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Fe65 is required for Tip60-directed histone H4 acetylation at DNA strand breaks.
Volume: 106
Issue: 13
Pages: 5093-8
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Publication
16227578 | J:102174
First Author: Hoe HS
Year: 2005
Journal: Mol Cell Biol
Title: F-spondin interaction with the apolipoprotein E receptor ApoEr2 affects processing of amyloid precursor protein.
Volume: 25
Issue: 21
Pages: 9259-68
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Publication
10537029 | J:59692
First Author: Guénette SY
Year: 1999
Journal: Neurobiol Aging
Title: Progress toward valid transgenic mouse models for Alzheimer's disease.
Volume: 20
Issue: 2
Pages: 201-11
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Publication
11912189 | J:113982
First Author: Taru H
Year: 2002
Journal: J Biol Chem
Title: Interaction of Alzheimer's beta -amyloid precursor family proteins with scaffold proteins of the JNK signaling cascade.
Volume: 277
Issue: 22
Pages: 20070-8
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Publication
12011466 | J:230367
First Author: Roncarati R
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling.
Volume: 99
Issue: 10
Pages: 7102-7
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