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Search results 601 to 700 out of 1236 for Cdkn2a

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Category: Publication
Type Details Score
Publication
First Author: Zhang H
Year: 2012
Journal: Blood
Title: HIF1α is required for survival maintenance of chronic myeloid leukemia stem cells.
Volume: 119
Issue: 11
Pages: 2595-607
Publication
First Author: Dineen SP
Year: 2010
Journal: Cancer Res
Title: Smac mimetic increases chemotherapy response and improves survival in mice with pancreatic cancer.
Volume: 70
Issue: 7
Pages: 2852-61
Publication
First Author: Guillaumond F
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma.
Volume: 110
Issue: 10
Pages: 3919-24
Publication
First Author: Guillaumond F
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma.
Volume: 112
Issue: 8
Pages: 2473-8
Publication
First Author: Menon R
Year: 2009
Journal: Cancer Res
Title: Identification of novel alternative splice isoforms of circulating proteins in a mouse model of human pancreatic cancer.
Volume: 69
Issue: 1
Pages: 300-9
Publication
First Author: Loncle C
Year: 2015
Journal: Cancer Res
Title: IL17 Functions through the Novel REG3β-JAK2-STAT3 Inflammatory Pathway to Promote the Transition from Chronic Pancreatitis to Pancreatic Cancer.
Volume: 75
Issue: 22
Pages: 4852-62
Publication
First Author: Singh A
Year: 2009
Journal: Cancer Cell
Title: A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival.
Volume: 15
Issue: 6
Pages: 489-500
Publication
First Author: Wang Z
Year: 2011
Journal: PLoS One
Title: Activated K-ras and INK4a/Arf deficiency cooperate during the development of pancreatic cancer by activation of Notch and NF-κB signaling pathways.
Volume: 6
Issue: 6
Pages: e20537
Publication
First Author: Vincent DF
Year: 2009
Journal: PLoS Genet
Title: Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas.
Volume: 5
Issue: 7
Pages: e1000575
Publication
First Author: Faca VM
Year: 2008
Journal: PLoS Med
Title: A mouse to human search for plasma proteome changes associated with pancreatic tumor development.
Volume: 5
Issue: 6
Pages: e123
Publication
First Author: Kelly-Spratt KS
Year: 2011
Journal: PLoS One
Title: Plasma proteome profiles associated with inflammation, angiogenesis, and cancer.
Volume: 6
Issue: 5
Pages: e19721
Publication
First Author: Leca J
Year: 2016
Journal: J Clin Invest
Title: Cancer-associated fibroblast-derived annexin A6+ extracellular vesicles support pancreatic cancer aggressiveness.
Volume: 126
Issue: 11
Pages: 4140-4156
Publication
First Author: Dominguez CX
Year: 2020
Journal: Cancer Discov
Title: Single-Cell RNA Sequencing Reveals Stromal Evolution into LRRC15+ Myofibroblasts as a Determinant of Patient Response to Cancer Immunotherapy.
Volume: 10
Issue: 2
Pages: 232-253
Publication
First Author: Gouirand V
Year: 2022
Journal: EMBO J
Title: Ketogenic HMG-CoA lyase and its product β-hydroxybutyrate promote pancreatic cancer progression.
Volume: 41
Issue: 9
Pages: e110466
Publication
First Author: Berry DC
Year: 2017
Journal: Cell Metab
Title: Cellular Aging Contributes to Failure of Cold-Induced Beige Adipocyte Formation in Old Mice and Humans.
Volume: 25
Issue: 1
Pages: 166-181
Publication
First Author: Ueda S
Year: 2021
Journal: Sci Rep
Title: TGF-β1 is involved in senescence-related pathways in glomerular endothelial cells via p16 translocation and p21 induction.
Volume: 11
Issue: 1
Pages: 21643
Publication
First Author: Shin CH
Year: 2017
Journal: Oncogene
Title: HBEGF promotes gliomagenesis in the context of Ink4a/Arf and Pten loss.
Volume: 36
Issue: 32
Pages: 4610-4618
Publication
First Author: Medyouf H
Year: 2010
Journal: Blood
Title: Acute T-cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss.
Volume: 115
Issue: 6
Pages: 1175-84
Publication
First Author: Ji ML
Year: 2023
Journal: Am J Hum Genet
Title: Dynamic chromatin accessibility tuning by the long noncoding RNA ELDR accelerates chondrocyte senescence and osteoarthritis.
Volume: 110
Issue: 4
Pages: 606-624
Publication
First Author: Ohtsuka Y
Year: 2006
Journal: Eur Respir J
Title: Genetic linkage analysis of pulmonary fibrotic response to silica in mice.
Volume: 28
Issue: 5
Pages: 1013-9
Publication
First Author: Ohkawa Y
Year: 2021
Journal: Mol Cancer Res
Title: Heparan Sulfate Synthesized by Ext1 Regulates Receptor Tyrosine Kinase Signaling and Promotes Resistance to EGFR Inhibitors in GBM.
Volume: 19
Issue: 1
Pages: 150-161
Publication
First Author: Perez-Campo FM
Year: 2014
Journal: Stem Cells
Title: MOZ-mediated repression of p16(INK) (4) (a) is critical for the self-renewal of neural and hematopoietic stem cells.
Volume: 32
Issue: 6
Pages: 1591-601
Publication
First Author: Liu X
Year: 2021
Journal: Nat Commun
Title: Osteoclasts protect bone blood vessels against senescence through the angiogenin/plexin-B2 axis.
Volume: 12
Issue: 1
Pages: 1832
Publication
First Author: Park BM
Year: 2018
Journal: Lab Anim Res
Title: Generation of knockout mouse models of cyclin-dependent kinase inhibitors by engineered nuclease-mediated genome editing.
Volume: 34
Issue: 4
Pages: 264-269
Publication
First Author: Koyano T
Year: 2019
Journal: Sci Rep
Title: The p21 dependent G2 arrest of the cell cycle in epithelial tubular cells links to the early stage of renal fibrosis.
Volume: 9
Issue: 1
Pages: 12059
Publication
First Author: Bothner B
Year: 2001
Journal: J Mol Biol
Title: Defining the molecular basis of Arf and Hdm2 interactions.
Volume: 314
Issue: 2
Pages: 263-77
Publication
First Author: Li DQ
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Bidirectional autoregulatory mechanism of metastasis-associated protein 1-alternative reading frame pathway in oncogenesis.
Volume: 108
Issue: 21
Pages: 8791-6
Publication
First Author: Gadd M
Year: 2001
Journal: Cancer Res
Title: Regulation of cyclin D1 and p16(INK4A) is critical for growth arrest during mammary involution.
Volume: 61
Issue: 24
Pages: 8811-9
Publication
First Author: Pines J
Year: 1997
Journal: Biochim Biophys Acta
Title: Cyclin-dependent kinase inhibitors: the age of crystals.
Volume: 1332
Issue: 1
Pages: M39-42
Publication
First Author: Schreiner B
Year: 2003
Journal: Oncogene
Title: Murine pancreatic tumor cell line TD2 bears the characteristic pattern of genetic changes with two independently amplified gene loci.
Volume: 22
Issue: 43
Pages: 6802-9
Publication
First Author: di Tommaso A
Year: 2009
Journal: Exp Cell Res
Title: Residues in the alternative reading frame tumor suppressor that influence its stability and p53-independent activities.
Volume: 315
Issue: 7
Pages: 1326-35
Publication
First Author: Agherbi H
Year: 2009
Journal: PLoS One
Title: Polycomb mediated epigenetic silencing and replication timing at the INK4a/ARF locus during senescence.
Volume: 4
Issue: 5
Pages: e5622
Publication
First Author: Ginjala V
Year: 2011
Journal: Mol Cell Biol
Title: BMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repair.
Volume: 31
Issue: 10
Pages: 1972-82
Publication
First Author: Mei J
Year: 2011
Journal: Mol Cell Biol
Title: MicroRNA-146a inhibits glioma development by targeting Notch1.
Volume: 31
Issue: 17
Pages: 3584-92
Publication
First Author: Holmfeldt L
Year: 2013
Journal: Nat Genet
Title: The genomic landscape of hypodiploid acute lymphoblastic leukemia.
Volume: 45
Issue: 3
Pages: 242-52
Publication
First Author: Zhou JX
Year: 2013
Journal: J Clin Invest
Title: Combined modulation of polycomb and trithorax genes rejuvenates β cell replication.
Volume: 123
Issue: 11
Pages: 4849-58
Publication
First Author: Zeng N
Year: 2013
Journal: Aging Cell
Title: PTEN controls β-cell regeneration in aged mice by regulating cell cycle inhibitor p16ink4a.
Volume: 12
Issue: 6
Pages: 1000-11
Publication
First Author: Churchman ML
Year: 2015
Journal: Cancer Cell
Title: Efficacy of Retinoids in IKZF1-Mutated BCR-ABL1 Acute Lymphoblastic Leukemia.
Volume: 28
Issue: 3
Pages: 343-56
Publication
First Author: De Jaime-Soguero A
Year: 2017
Journal: PLoS Genet
Title: Wnt/Tcf1 pathway restricts embryonic stem cell cycle through activation of the Ink4/Arf locus.
Volume: 13
Issue: 3
Pages: e1006682
Publication
First Author: Yoshida Y
Year: 2014
Journal: PLoS One
Title: Notch signaling regulates the lifespan of vascular endothelial cells via a p16-dependent pathway.
Volume: 9
Issue: 6
Pages: e100359
Publication  
First Author: Carlos AR
Year: 2013
Journal: Nat Commun
Title: ARF triggers senescence in Brca2-deficient cells by altering the spectrum of p53 transcriptional targets.
Volume: 4
Pages: 2697
Publication
First Author: Yetil A
Year: 2015
Journal: Oncotarget
Title: p19ARF is a critical mediator of both cellular senescence and an innate immune response associated with MYC inactivation in mouse model of acute leukemia.
Volume: 6
Issue: 6
Pages: 3563-77
Publication
First Author: Luo C
Year: 2018
Journal: J Am Soc Nephrol
Title: Wnt9a Promotes Renal Fibrosis by Accelerating Cellular Senescence in Tubular Epithelial Cells.
Volume: 29
Issue: 4
Pages: 1238-1256
Publication  
First Author: Liang Y
Year: 2022
Journal: Oxid Med Cell Longev
Title: p16(INK4a) Plays Critical Role in Exacerbating Inflammaging in High Fat Diet Induced Skin.
Volume: 2022
Pages: 3415528
Publication
First Author: Sashida G
Year: 2009
Journal: Mol Cell Biol
Title: ELF4/MEF activates MDM2 expression and blocks oncogene-induced p16 activation to promote transformation.
Volume: 29
Issue: 13
Pages: 3687-99
Publication
First Author: Quelle DE
Year: 1995
Journal: Oncogene
Title: Cloning and characterization of murine p16INK4a and p15INK4b genes.
Volume: 11
Issue: 4
Pages: 635-45
Publication
First Author: Zhang S
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Cdkn2a, the cyclin-dependent kinase inhibitor encoding p16INK4a and p19ARF, is a candidate for the plasmacytoma susceptibility locus, Pctr1.
Volume: 95
Issue: 5
Pages: 2429-34
Publication
First Author: Kajiro M
Year: 2011
Journal: PLoS One
Title: The E3 ubiquitin ligase activity of Trip12 is essential for mouse embryogenesis.
Volume: 6
Issue: 10
Pages: e25871
Publication  
First Author: Sawaki D
Year: 2023
Journal: JCI Insight
Title: Osteopontin promotes age-related adipose tissue remodeling through senescence-associated macrophage dysfunction.
Volume: 8
Issue: 8
Publication
First Author: Debbache J
Year: 2012
Journal: Genetics
Title: In vivo role of alternative splicing and serine phosphorylation of the microphthalmia-associated transcription factor.
Volume: 191
Issue: 1
Pages: 133-44
Publication
First Author: Bejarano L
Year: 2017
Journal: Cancer Cell
Title: Inhibition of TRF1 Telomere Protein Impairs Tumor Initiation and Progression in Glioblastoma Mouse Models and Patient-Derived Xenografts.
Volume: 32
Issue: 5
Pages: 590-607.e4
Publication
First Author: Yamashita M
Year: 2008
Journal: J Exp Med
Title: Bmi1 regulates memory CD4 T cell survival via repression of the Noxa gene.
Volume: 205
Issue: 5
Pages: 1109-20
Publication
First Author: Sitaram A
Year: 2012
Journal: Mol Biol Cell
Title: Differential recognition of a dileucine-based sorting signal by AP-1 and AP-3 reveals a requirement for both BLOC-1 and AP-3 in delivery of OCA2 to melanosomes.
Volume: 23
Issue: 16
Pages: 3178-92
Publication
First Author: Zhu P
Year: 2019
Journal: Nat Commun
Title: The transcription factor Slug represses p16Ink4a and regulates murine muscle stem cell aging.
Volume: 10
Issue: 1
Pages: 2568
Publication
First Author: Hume AN
Year: 2006
Journal: Mol Biol Cell
Title: A coiled-coil domain of melanophilin is essential for Myosin Va recruitment and melanosome transport in melanocytes.
Volume: 17
Issue: 11
Pages: 4720-35
Publication
First Author: Skowronska-Krawczyk D
Year: 2015
Journal: Mol Cell
Title: P16INK4a Upregulation Mediated by SIX6 Defines Retinal Ganglion Cell Pathogenesis in Glaucoma.
Volume: 59
Issue: 6
Pages: 931-40
Publication
First Author: Scott CL
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Role of the chromobox protein CBX7 in lymphomagenesis.
Volume: 104
Issue: 13
Pages: 5389-94
Publication
First Author: Zou ZV
Year: 2020
Journal: Sci Rep
Title: Genomic profiling of the transcription factor Zfp148 and its impact on the p53 pathway.
Volume: 10
Issue: 1
Pages: 14156
Publication
First Author: Buchstaller J
Year: 2012
Journal: Cancer Cell
Title: Tumorigenic cells are common in mouse MPNSTs but their frequency depends upon tumor genotype and assay conditions.
Volume: 21
Issue: 2
Pages: 240-52
Publication
First Author: Bondar T
Year: 2010
Journal: Cell Stem Cell
Title: p53-mediated hematopoietic stem and progenitor cell competition.
Volume: 6
Issue: 4
Pages: 309-22
Publication
First Author: Wendel HG
Year: 2006
Journal: Cancer Res
Title: Determinants of sensitivity and resistance to rapamycin-chemotherapy drug combinations in vivo.
Volume: 66
Issue: 15
Pages: 7639-46
Publication
First Author: Terzian T
Year: 2008
Journal: Genes Dev
Title: The inherent instability of mutant p53 is alleviated by Mdm2 or p16INK4a loss.
Volume: 22
Issue: 10
Pages: 1337-44
Publication
First Author: Tomás-Loba A
Year: 2008
Journal: Cell
Title: Telomerase reverse transcriptase delays aging in cancer-resistant mice.
Volume: 135
Issue: 4
Pages: 609-22
Publication
First Author: International Cancer Genome Consortium PedBrain Tumor Project.
Year: 2016
Journal: Nat Med
Title: Recurrent MET fusion genes represent a drug target in pediatric glioblastoma.
Volume: 22
Issue: 11
Pages: 1314-1320
Publication
First Author: Schmitt CA
Year: 1999
Journal: Genes Dev
Title: INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.
Volume: 13
Issue: 20
Pages: 2670-7
Publication
First Author: Fisher GH
Year: 2001
Journal: Genes Dev
Title: Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes.
Volume: 15
Issue: 24
Pages: 3249-62
Publication
First Author: Williams TM
Year: 2004
Journal: J Biol Chem
Title: Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: role of INK4a/CAV-1 in mammary epithelial cell hyperplasia.
Volume: 279
Issue: 23
Pages: 24745-56
Publication
First Author: Lu Y
Year: 2001
Journal: Mol Cell Biol
Title: Disruption of the Cockayne syndrome B gene impairs spontaneous tumorigenesis in cancer-predisposed Ink4a/ARF knockout mice.
Volume: 21
Issue: 5
Pages: 1810-8
Publication  
First Author: Schmitt CA
Year: 2000
Journal: Cold Spring Harb Symp Quant Biol
Title: DNA damage responses and chemosensitivity in the E mu-myc mouse lymphoma model.
Volume: 65
Pages: 499-510
Publication
First Author: Zhou J
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Bmi-1 determines the stemness of renal stem or progenitor cells.
Volume: 529
Issue: 4
Pages: 1165-1172
Publication
First Author: Suh YA
Year: 2011
Journal: Cancer Res
Title: Multiple stress signals activate mutant p53 in vivo.
Volume: 71
Issue: 23
Pages: 7168-75
Publication
First Author: Kwon MC
Year: 2013
Journal: Mol Oncol
Title: Mouse models for lung cancer.
Volume: 7
Issue: 2
Pages: 165-77
Publication
First Author: Joseph NM
Year: 2008
Journal: Cancer Cell
Title: The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem cells.
Volume: 13
Issue: 2
Pages: 129-40
Publication
First Author: Jin X
Year: 2012
Journal: Mol Cancer Res
Title: Inactivation of heat shock factor Hsf4 induces cellular senescence and suppresses tumorigenesis in vivo.
Volume: 10
Issue: 4
Pages: 523-34
Publication
First Author: Panattoni M
Year: 2008
Journal: J Exp Med
Title: Targeted inactivation of the COP9 signalosome impairs multiple stages of T cell development.
Volume: 205
Issue: 2
Pages: 465-77
Publication
First Author: Martín-Caballero J
Year: 2004
Journal: Oncogene
Title: Different cooperating effect of p21 or p27 deficiency in combination with INK4a/ARF deletion in mice.
Volume: 23
Issue: 50
Pages: 8231-7
Publication
First Author: Vafaie F
Year: 2014
Journal: Aging Cell
Title: Collagenase-resistant collagen promotes mouse aging and vascular cell senescence.
Volume: 13
Issue: 1
Pages: 121-30
Publication
First Author: Garcia-Diaz C
Year: 2023
Journal: Cell Rep
Title: Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin.
Volume: 42
Issue: 5
Pages: 112472
Publication
First Author: Gon S
Year: 2018
Journal: Haematologica
Title: Fit αβ T-cell receptor suppresses leukemogenesis of Pten-deficient thymocytes.
Volume: 103
Issue: 6
Pages: 999-1007
Publication
First Author: Weiss WA
Year: 2003
Journal: Cancer Res
Title: Genetic determinants of malignancy in a mouse model for oligodendroglioma.
Volume: 63
Issue: 7
Pages: 1589-95
Publication
First Author: Halaban R
Year: 1998
Journal: Oncogene
Title: Release of cell cycle constraints in mouse melanocytes by overexpressed mutant E2F1E132, but not by deletion of p16INK4A or p21WAF1/CIP1.
Volume: 16
Issue: 19
Pages: 2489-501
Publication  
First Author: Sato S
Year: 2015
Journal: Nat Commun
Title: Ablation of the p16(INK4a) tumour suppressor reverses ageing phenotypes of klotho mice.
Volume: 6
Pages: 7035
Publication  
First Author: Patel AV
Year: 2016
Journal: EBioMedicine
Title: An ShRNA Screen Identifies MEIS1 as a Driver of Malignant Peripheral Nerve Sheath Tumors.
Volume: 9
Pages: 110-119
Publication  
First Author: Sheikh BN
Year: 2017
Journal: Exp Hematol
Title: MOZ and BMI1 act synergistically to maintain hematopoietic stem cells.
Volume: 47
Pages: 83-97.e8
Publication
First Author: Bardeesy N
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse.
Volume: 103
Issue: 15
Pages: 5947-52
Publication
First Author: Monahan KB
Year: 2010
Journal: Oncogene
Title: Somatic p16(INK4a) loss accelerates melanomagenesis.
Volume: 29
Issue: 43
Pages: 5809-17
Publication  
First Author: Perez BA
Year: 2013
Journal: Front Oncol
Title: Assessing the radiation response of lung cancer with different gene mutations using genetically engineered mice.
Volume: 3
Pages: 72
Publication
First Author: Hambardzumyan D
Year: 2009
Journal: Transl Oncol
Title: Modeling Adult Gliomas Using RCAS/t-va Technology.
Volume: 2
Issue: 2
Pages: 89-95
Publication
First Author: Frank KM
Year: 2000
Journal: Mol Cell
Title: DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway.
Volume: 5
Issue: 6
Pages: 993-1002
Publication
First Author: Hernández-Porras I
Year: 2016
Journal: J Pathol
Title: K-Ras(V14I) -induced Noonan syndrome predisposes to tumour development in mice.
Volume: 239
Issue: 2
Pages: 206-17
Publication
First Author: Kadariya Y
Year: 2016
Journal: Cancer Prev Res (Phila)
Title: Inflammation-Related IL1β/IL1R Signaling Promotes the Development of Asbestos-Induced Malignant Mesothelioma.
Volume: 9
Issue: 5
Pages: 406-414
Publication
First Author: Jansen AJ
Year: 2012
Journal: Blood
Title: Desialylation accelerates platelet clearance after refrigeration and initiates GPIbα metalloproteinase-mediated cleavage in mice.
Volume: 119
Issue: 5
Pages: 1263-73
Publication
First Author: Shah M
Year: 2010
Journal: PLoS Genet
Title: A role for ATF2 in regulating MITF and melanoma development.
Volume: 6
Issue: 12
Pages: e1001258
Publication
First Author: Zhu H
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis.
Volume: 106
Issue: 8
Pages: 2712-6
Publication
First Author: Page A
Year: 2017
Journal: Mol Cancer Res
Title: IKKβ-Mediated Resistance to Skin Cancer Development Is Ink4a/Arf-Dependent.
Volume: 15
Issue: 9
Pages: 1255-1264
Publication  
First Author: Piunti A
Year: 2014
Journal: Nat Commun
Title: Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication.
Volume: 5
Pages: 3649
Publication
First Author: Wang X
Year: 2020
Journal: J Cell Physiol
Title: The proinflammatory cytokines IL-1β and TNF-α modulate corneal epithelial wound healing through p16(Ink4a) suppressing STAT3 activity.
Volume: 235
Issue: 12
Pages: 10081-10093
Publication
First Author: Fufa TD
Year: 2015
Journal: Hum Mol Genet
Title: Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes.
Volume: 24
Issue: 19
Pages: 5433-50
Publication
First Author: Tuncer E
Year: 2019
Journal: J Clin Invest
Title: SMAD signaling promotes melanoma metastasis independently of phenotype switching.
Volume: 129
Issue: 7
Pages: 2702-2716
Publication
First Author: Fragola G
Year: 2013
Journal: PLoS Genet
Title: Cell reprogramming requires silencing of a core subset of polycomb targets.
Volume: 9
Issue: 2
Pages: e1003292