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Search results 601 to 700 out of 2663 for Psen1

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Type Details Score
Publication
38243688 | J:350730
First Author: Yamada C
Year: 2024
Journal: J Periodontal Res
Title: Dementia exacerbates periodontal bone loss in females.
Volume: 59
Issue: 3
Pages: 512-520
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Publication
38539620 | J:350679
 
First Author: Zhang W
Year: 2024
Journal: Brain Sci
Title: Dendrobine Ameliorates Alzheimer's Disease-like Pathology and Cognitive Decline in 3 × Tg-AD Mice.
Volume: 14
Issue: 3
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Publication
26503550 | J:269053
 
First Author: Yang SH
Year: 2015
Journal: Sci Rep
Title: Abnormalities of plasma cytokines and spleen in senile APP/PS1/Tau transgenic mouse model.
Volume: 5
Pages: 15703
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Publication
27897204 | J:287498
 
First Author: Oka S
Year: 2016
Journal: Sci Rep
Title: Human mitochondrial transcriptional factor A breaks the mitochondria-mediated vicious cycle in Alzheimer's disease.
Volume: 6
Pages: 37889
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Publication
38500108 | J:350688
First Author: Jagadeesan N
Year: 2024
Journal: J Transl Med
Title: Modulation of hippocampal protein expression by a brain penetrant biologic TNF-α inhibitor in the 3xTg Alzheimer's disease mice.
Volume: 22
Issue: 1
Pages: 291
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Publication
24623762 | J:209607
First Author: Born HA
Year: 2014
Journal: J Neurosci
Title: Genetic suppression of transgenic APP rescues Hypersynchronous network activity in a mouse model of Alzeimer's disease.
Volume: 34
Issue: 11
Pages: 3826-40
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Publication
17251414 | J:117782
First Author: Billings LM
Year: 2007
Journal: J Neurosci
Title: Learning decreases A beta*56 and tau pathology and ameliorates behavioral decline in 3xTg-AD mice.
Volume: 27
Issue: 4
Pages: 751-61
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Publication
38486986 | J:350690
First Author: Li Y
Year: 2024
Journal: Acta Pharm Sin B
Title: Multidimensional autophagy nano-regulator boosts Alzheimer's disease treatment by improving both extra/intraneuronal homeostasis.
Volume: 14
Issue: 3
Pages: 1380-1399
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Publication
32993686 | J:313508
First Author: Robison LS
Year: 2020
Journal: J Neuroinflammation
Title: Role of sex and high-fat diet in metabolic and hypothalamic disturbances in the 3xTg-AD mouse model of Alzheimer's disease.
Volume: 17
Issue: 1
Pages: 285
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Publication
19605645 | J:151572
First Author: Ma QL
Year: 2009
Journal: J Neurosci
Title: Beta-amyloid oligomers induce phosphorylation of tau and inactivation of insulin receptor substrate via c-Jun N-terminal kinase signaling: suppression by omega-3 fatty acids and curcumin.
Volume: 29
Issue: 28
Pages: 9078-89
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Publication
18423383 | J:136275
First Author: Resende R
Year: 2008
Journal: Free Radic Biol Med
Title: Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease.
Volume: 44
Issue: 12
Pages: 2051-7
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Publication
33052247 | J:313523
First Author: Shen Y
Year: 2020
Journal: Theranostics
Title: Ultrasound with microbubbles improves memory, ameliorates pathology and modulates hippocampal proteomic changes in a triple transgenic mouse model of Alzheimer's disease.
Volume: 10
Issue: 25
Pages: 11794-11819
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Publication
25582787 | J:219735
 
First Author: Barr CM
Year: 2015
Journal: Neurosci Lett
Title: Submyeloablative conditioning with busulfan permits bone marrow-derived cell accumulation in a murine model of Alzheimer's disease.
Volume: 588
Pages: 196-201
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Publication
29920240 | J:272426
First Author: Sejimo S
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Scallop-derived plasmalogens attenuate the activation of PKCδ associated with the brain inflammation.
Volume: 503
Issue: 2
Pages: 837-842
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Publication
36052130 | J:327932
 
First Author: Bjorkli C
Year: 2022
Journal: Front Pharmacol
Title: Combined targeting of pathways regulating synaptic formation and autophagy attenuates Alzheimer's disease pathology in mice.
Volume: 13
Pages: 913971
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Publication
25362032 | J:360690
First Author: Acquaah-Mensah GK
Year: 2015
Journal: J Alzheimers Dis
Title: A regulatory role for the insulin- and BDNF-linked RORA in the hippocampus: implications for Alzheimer's disease.
Volume: 44
Issue: 3
Pages: 827-38
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Publication
37091517 | J:345692
 
First Author: Batista A
Year: 2023
Journal: Front Aging Neurosci
Title: Normative mice retinal thickness: 16-month longitudinal characterization of wild-type mice and changes in a model of Alzheimer's disease.
Volume: 15
Pages: 1161847
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Publication
28411106 | J:256732
First Author: Esteve C
Year: 2017
Journal: Biochim Biophys Acta
Title: Mass spectrometry imaging shows major derangements in neurogranin and in purine metabolism in the triple-knockout 3×Tg Alzheimer mouse model.
Volume: 1865
Issue: 7
Pages: 747-754
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Publication
35011699 | J:322134
 
First Author: Fernandes A
Year: 2022
Journal: Cells
Title: Differences in Immune-Related Genes Underlie Temporal and Regional Pathological Progression in 3xTg-AD Mice.
Volume: 11
Issue: 1
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Publication
39351497 | J:359235
 
First Author: McNerney MW
Year: 2023
Journal: Exp Gerontol
Title: Memory-related hippocampal brain-derived neurotrophic factor activation pathways from repetitive transcranial magnetic stimulation in the 3xTg-AD mouse line.
Volume: 183
Pages: 112323
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Publication
37586250 | J:339654
 
First Author: Sangineto M
Year: 2023
Journal: Redox Biol
Title: Metabolic reprogramming in inflammatory microglia indicates a potential way of targeting inflammation in Alzheimer's disease.
Volume: 66
Pages: 102846
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Publication
35443751 | J:324344
First Author: Hamilton LK
Year: 2022
Journal: Nat Commun
Title: Stearoyl-CoA Desaturase inhibition reverses immune, synaptic and cognitive impairments in an Alzheimer's disease mouse model.
Volume: 13
Issue: 1
Pages: 2061
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Publication
31103943 | J:281609
 
First Author: Castano-Prat P
Year: 2019
Journal: Neurobiol Aging
Title: Altered slow (<1 Hz) and fast (beta and gamma) neocortical oscillations in the 3xTg-AD mouse model of Alzheimer's disease under anesthesia.
Volume: 79
Pages: 142-151
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Publication
33771205 | J:360691
First Author: Koh SH
Year: 2021
Journal: Alzheimers Res Ther
Title: Efficacy and safety of GV1001 in patients with moderate-to-severe Alzheimer's disease already receiving donepezil: a phase 2 randomized, double-blind, placebo-controlled, multicenter clinical trial.
Volume: 13
Issue: 1
Pages: 66
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Publication
27105281 | J:350774
First Author: Chu TT
Year: 2016
Journal: Cell Chem Biol
Title: Specific Knockdown of Endogenous Tau Protein by Peptide-Directed Ubiquitin-Proteasome Degradation.
Volume: 23
Issue: 4
Pages: 453-61
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Publication
39225174 | J:360719
First Author: Yu L
Year: 2024
Journal: Phytother Res
Title: Thonningianin A from Penthorum chinense Pursh as a targeted inhibitor of Alzheimer's disease-related β-amyloid and Tau proteins.
Volume: 38
Issue: 9
Pages: 4815-4831
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Publication
23500896 | J:197528
 
First Author: Davis KE
Year: 2013
Journal: Behav Brain Res
Title: Episodic-like memory is sensitive to both Alzheimer's-like pathological accumulation and normal ageing processes in mice.
Volume: 254
Pages: 73-82
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Publication
39532829 | J:360717
     
First Author: Wu CY
Year: 2024
Journal: Geroscience
Title: ACSL3 is a promising therapeutic target for alleviating anxiety and depression in Alzheimer's disease.
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Publication
21918687 | J:176128
First Author: Chen S
Year: 2011
Journal: PLoS One
Title: Allopregnanolone promotes regeneration and reduces β-amyloid burden in a preclinical model of Alzheimer's disease.
Volume: 6
Issue: 8
Pages: e24293
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Publication
16687509 | J:108684
First Author: Stutzmann GE
Year: 2006
Journal: J Neurosci
Title: Enhanced ryanodine receptor recruitment contributes to Ca2+ disruptions in young, adult, and aged Alzheimer's disease mice.
Volume: 26
Issue: 19
Pages: 5180-9
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Publication
35431906 | J:323889
 
First Author: Carvalho da Silva AM
Year: 2022
Journal: Front Aging Neurosci
Title: Simultaneous Alteration of the Circadian Variation of Memory, Hippocampal Synaptic Plasticity, and Metabolism in a Triple Transgenic Mouse Model of Alzheimer's Disease.
Volume: 14
Pages: 835885
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Publication
37185578 | J:350062
First Author: Noel RL
Year: 2023
Journal: Sci Rep
Title: Natural aging and Alzheimer's disease pathology increase susceptibility to focused ultrasound-induced blood-brain barrier opening.
Volume: 13
Issue: 1
Pages: 6757
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Publication
39448026 | J:360699
 
First Author: Carvalho D
Year: 2025
Journal: J Proteomics
Title: Untargeted metabolomics of 3xTg-AD neurotoxic astrocytes.
Volume: 310
Pages: 105336
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Publication
27255814 | J:234996
 
First Author: Vandal M
Year: 2016
Journal: Neurobiol Aging
Title: Impaired thermoregulation and beneficial effects of thermoneutrality in the 3×Tg-AD model of Alzheimer's disease.
Volume: 43
Pages: 47-57
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Publication
31427599 | J:284641
First Author: Park SJ
Year: 2019
Journal: Sci Rep
Title: Visualizing Alzheimer's Disease Mouse Brain with Multispectral Optoacoustic Tomography using a Fluorescent probe, CDnir7.
Volume: 9
Issue: 1
Pages: 12052
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Publication
27103531 | J:235027
 
First Author: Moreno-Castilla P
Year: 2016
Journal: Neurobiol Aging
Title: Dopaminergic neurotransmission dysfunction induced by amyloid-β transforms cortical long-term potentiation into long-term depression and produces memory impairment.
Volume: 41
Pages: 187-199
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Publication
11262239 | J:67969
First Author: Koizumi K
Year: 2001
Journal: Development
Title: The role of presenilin 1 during somite segmentation.
Volume: 128
Issue: 8
Pages: 1391-402
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Publication
21559374 | J:172347
First Author: Saura CA
Year: 2011
Journal: PLoS One
Title: Presenilin/γ-secretase regulates neurexin processing at synapses.
Volume: 6
Issue: 4
Pages: e19430
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Publication
22336193 | J:191170
First Author: Guo Q
Year: 2012
Journal: Neurobiol Aging
Title: Central CRF system perturbation in an Alzheimer's disease knockin mouse model.
Volume: 33
Issue: 11
Pages: 2678-91
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Publication
22144675 | J:181521
First Author: Guo Q
Year: 2012
Journal: J Biol Chem
Title: Amyloid precursor protein revisited: neuron-specific expression and highly stable nature of soluble derivatives.
Volume: 287
Issue: 4
Pages: 2437-45
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Publication
16723713 | J:109124
First Author: Kitazawa M
Year: 2006
Journal: Am J Pathol
Title: Genetically augmenting Abeta42 levels in skeletal muscle exacerbates inclusion body myositis-like pathology and motor deficits in transgenic mice.
Volume: 168
Issue: 6
Pages: 1986-97
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10448051 | J:57518
First Author: McGowan E
Year: 1999
Journal: Neurobiol Dis
Title: Amyloid phenotype characterization of transgenic mice overexpressing both mutant amyloid precursor protein and mutant presenilin 1 transgenes.
Volume: 6
Issue: 4
Pages: 231-44
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Publication
27499089 | J:283300
First Author: Di Meco A
Year: 2017
Journal: Biol Psychiatry
Title: 12/15-Lipoxygenase Inhibition Reverses Cognitive Impairment, Brain Amyloidosis, and Tau Pathology by Stimulating Autophagy in Aged Triple Transgenic Mice.
Volume: 81
Issue: 2
Pages: 92-100
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Publication
27143420 | J:235010
 
First Author: Nikolakopoulou AM
Year: 2016
Journal: Neurobiol Aging
Title: Presenilin 1 promotes trypsin-induced neuroprotection via the PAR2/ERK signaling pathway. Effects of presenilin 1 FAD mutations.
Volume: 42
Pages: 41-9
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Publication
24332986 | J:212730
First Author: Joshi YB
Year: 2014
Journal: Neurobiol Aging
Title: Modulation of lipopolysaccharide-induced memory insult, γ-secretase, and neuroinflammation in triple transgenic mice by 5-lipoxygenase.
Volume: 35
Issue: 5
Pages: 1024-31
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Publication
23634895 | J:214888
First Author: Joshi YB
Year: 2013
Journal: Aging Cell
Title: Knockout of 5-lipoxygenase prevents dexamethasone-induced tau pathology in 3xTg mice.
Volume: 12
Issue: 4
Pages: 706-11
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Publication
25122659 | J:216418
First Author: Joshi YB
Year: 2014
Journal: Hum Mol Genet
Title: Absence of ALOX5 gene prevents stress-induced memory deficits, synaptic dysfunction and tauopathy in a mouse model of Alzheimer's disease.
Volume: 23
Issue: 25
Pages: 6894-902
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Publication
39227892 | J:359285
First Author: Colussi C
Year: 2024
Journal: Stem Cell Res Ther
Title: Nucleoporin 153 deficiency in adult neural stem cells defines a pathological protein-network signature and defective neurogenesis in a mouse model of AD.
Volume: 15
Issue: 1
Pages: 275
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Publication
30872324 | J:276278
First Author: Aloni E
Year: 2019
Journal: J Neurosci
Title: Synaptopodin Deficiency Ameliorates Symptoms in the 3xTg Mouse Model of Alzheimer's Disease.
Volume: 39
Issue: 20
Pages: 3983-3992
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Publication
27460145 | J:239134
 
First Author: Thomsen MS
Year: 2016
Journal: Neurobiol Aging
Title: Lynx1 and Aβ1-42 bind competitively to multiple nicotinic acetylcholine receptor subtypes.
Volume: 46
Pages: 13-21
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Publication
37666180 | J:341175
 
First Author: Ho A
Year: 2023
Journal: Biomed Pharmacother
Title: IL-34 exacerbates pathogenic features of Alzheimer's disease and calvaria osteolysis in triple transgenic (3x-Tg) female mice.
Volume: 166
Pages: 115435
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Publication
36537556 | J:345297
First Author: Rosenberg N
Year: 2023
Journal: Glia
Title: Overexpression of UCP4 in astrocytic mitochondria prevents multilevel dysfunctions in a mouse model of Alzheimer's disease.
Volume: 71
Issue: 4
Pages: 957-973
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Publication
32332783 | J:289785
First Author: Dufort-Gervais J
Year: 2020
Journal: Sci Rep
Title: Neuroligin-1 is altered in the hippocampus of Alzheimer's disease patients and mouse models, and modulates the toxicity of amyloid-beta oligomers.
Volume: 10
Issue: 1
Pages: 6956
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Publication
31978364 | J:351230
First Author: Zheng J
Year: 2020
Journal: Cell Stem Cell
Title: Interneuron Accumulation of Phosphorylated tau Impairs Adult Hippocampal Neurogenesis by Suppressing GABAergic Transmission.
Volume: 26
Issue: 3
Pages: 331-345.e6
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Publication
28383037 | J:276110
 
First Author: Li JG
Year: 2017
Journal: Sci Rep
Title: Five lipoxygenase hypomethylation mediates the homocysteine effect on Alzheimer's phenotype.
Volume: 7
Pages: 46002
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Publication
20956308 | J:166233
First Author: Zhang Y
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model.
Volume: 107
Issue: 44
Pages: 19014-9
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Publication
38462603 | J:358974
First Author: Lei HY
Year: 2024
Journal: Mil Med Res
Title: Targeting vulnerable microcircuits in the ventral hippocampus of male transgenic mice to rescue Alzheimer-like social memory loss.
Volume: 11
Issue: 1
Pages: 16
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Publication
34260075 | J:311284
First Author: Chen C
Year: 2021
Journal: EMBO J
Title: Gut inflammation triggers C/EBPβ/δ-secretase-dependent gut-to-brain propagation of Aβ and Tau fibrils in Alzheimer's disease.
Volume: 40
Issue: 17
Pages: e106320
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Publication
35169045 | J:352651
First Author: Creighton SD
Year: 2022
Journal: Learn Mem
Title: Age-dependent attenuation of spatial memory deficits by the histone acetyltransferase p300/CBP-associated factor (PCAF) in 3xTG Alzheimer's disease mice.
Volume: 29
Issue: 3
Pages: 71-76
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Publication
27247180 | J:323755
 
First Author: Butkevich E
Year: 2016
Journal: Sci Rep
Title: Phosphorylation of FEZ1 by Microtubule Affinity Regulating Kinases regulates its function in presynaptic protein trafficking.
Volume: 6
Pages: 26965
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Publication
30689197 | J:336352
First Author: Leone L
Year: 2019
Journal: Mol Neurobiol
Title: Altered Nup153 Expression Impairs the Function of Cultured Hippocampal Neural Stem Cells Isolated from a Mouse Model of Alzheimer's Disease.
Volume: 56
Issue: 8
Pages: 5934-5949
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Publication
32130882 | J:286282
First Author: Le Douce J
Year: 2020
Journal: Cell Metab
Title: Impairment of Glycolysis-Derived l-Serine Production in Astrocytes Contributes to Cognitive Deficits in Alzheimer's Disease.
Volume: 31
Issue: 3
Pages: 503-517.e8
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Publication
33015060 | J:311333
 
First Author: Sun F
Year: 2020
Journal: Front Cell Dev Biol
Title: Upregulation of Prickle2 Ameliorates Alzheimer's Disease-Like Pathology in a Transgenic Mouse Model of Alzheimer's Disease.
Volume: 8
Pages: 565020
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Publication
30073505 | J:311364
First Author: Barone E
Year: 2019
Journal: Mol Neurobiol
Title: Biliverdin Reductase-A Mediates the Beneficial Effects of Intranasal Insulin in Alzheimer Disease.
Volume: 56
Issue: 4
Pages: 2922-2943
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Publication
33070372 | J:311352
First Author: Zhou Y
Year: 2020
Journal: FASEB J
Title: Polyphyllin I attenuates cognitive impairments and reduces AD-like pathology through CIP2A-PP2A signaling pathway in 3XTg-AD mice.
Volume: 34
Issue: 12
Pages: 16414-16431
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Publication
36498839 | J:334303
 
First Author: Lin YH
Year: 2022
Journal: Int J Mol Sci
Title: Zfra Inhibits the TRAPPC6AΔ-Initiated Pathway of Neurodegeneration.
Volume: 23
Issue: 23
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Publication
30594047 | J:276151
 
First Author: Shentu YP
Year: 2019
Journal: Neurobiol Aging
Title: CIP2A-promoted astrogliosis induces AD-like synaptic degeneration and cognitive deficits.
Volume: 75
Pages: 198-208
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Publication
22728099 | J:192517
 
First Author: Marques SC
Year: 2012
Journal: Neuroscience
Title: Epigenetic regulation of BACE1 in Alzheimer's disease patients and in transgenic mice.
Volume: 220
Pages: 256-66
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19914182 | J:155589
First Author: Zhang YW
Year: 2009
Journal: Neuron
Title: A functional mouse retroposed gene Rps23r1 reduces Alzheimer's beta-amyloid levels and tau phosphorylation.
Volume: 64
Issue: 3
Pages: 328-40
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Publication
25093460 | J:215753
First Author: Xu J
Year: 2014
Journal: PLoS Biol
Title: Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease.
Volume: 12
Issue: 8
Pages: e1001923
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Publication
19561098 | J:151661
First Author: Fonseca MI
Year: 2009
Journal: J Immunol
Title: Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease.
Volume: 183
Issue: 2
Pages: 1375-83
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Publication
23683389 | J:284655
First Author: Giannopoulos PF
Year: 2013
Journal: Biol Psychiatry
Title: 5-lipoxygenase activating protein reduction ameliorates cognitive deficit, synaptic dysfunction, and neuropathology in a mouse model of Alzheimer's disease.
Volume: 74
Issue: 5
Pages: 348-56
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Publication
18021291 | J:141555
First Author: Lopez JR
Year: 2008
Journal: J Neurochem
Title: Increased intraneuronal resting [Ca2+] in adult Alzheimer's disease mice.
Volume: 105
Issue: 1
Pages: 262-71
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21829458 | J:284814
First Author: Bianchi FT
Year: 2011
Journal: PLoS One
Title: The collagen chaperone HSP47 is a new interactor of APP that affects the levels of extracellular beta-amyloid peptides.
Volume: 6
Issue: 7
Pages: e22370
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Publication
25447943 | J:231418
 
First Author: Hohsfield LA
Year: 2014
Journal: Mol Cell Neurosci
Title: Vascular pathology of 20-month-old hypercholesterolemia mice in comparison to triple-transgenic and APPSwDI Alzheimer's disease mouse models.
Volume: 63
Pages: 83-95
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22367970 | J:183771
First Author: Manczak M
Year: 2012
Journal: Hum Mol Genet
Title: Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage.
Volume: 21
Issue: 11
Pages: 2538-47
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Publication
27470171 | J:236530
First Author: Höfling C
Year: 2016
Journal: Aging Cell
Title: Differential transgene expression patterns in Alzheimer mouse models revealed by novel human amyloid precursor protein-specific antibodies.
Volume: 15
Issue: 5
Pages: 953-63
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Publication
25947203 | J:351760
First Author: Plagg B
Year: 2015
Journal: Biogerontology
Title: Platelet dysfunction in hypercholesterolemia mice, two Alzheimer's disease mouse models and in human patients with Alzheimer's disease.
Volume: 16
Issue: 4
Pages: 543-58
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Publication
32920368 | J:348446
 
First Author: Danielyan L
Year: 2020
Journal: EBioMedicine
Title: Cell motility and migration as determinants of stem cell efficacy.
Volume: 60
Pages: 102989
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Publication
26159193 | J:264838
First Author: Plagg B
Year: 2015
Journal: Curr Alzheimer Res
Title: Increased Acetylation of Histone H4 at Lysine 12 (H4K12) in Monocytes of Transgenic Alzheimer's Mice and in Human Patients.
Volume: 12
Issue: 8
Pages: 752-60
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Publication
36451854 | J:348479
First Author: Yang H
Year: 2022
Journal: Theranostics
Title: Adoptive therapy with amyloid-β specific regulatory T cells alleviates Alzheimer's disease.
Volume: 12
Issue: 18
Pages: 7668-7680
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Publication
33192524 | J:313486
 
First Author: Iyaswamy A
Year: 2020
Journal: Front Pharmacol
Title: Yuan-Hu Zhi Tong Prescription Mitigates Tau Pathology and Alleviates Memory Deficiency in the Preclinical Models of Alzheimer's Disease.
Volume: 11
Pages: 584770
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Publication
18800967 | J:141307
First Author: Ribe EM
Year: 2008
Journal: Biochem J
Title: Mechanisms of neuronal death in disease: defining the models and the players.
Volume: 415
Issue: 2
Pages: 165-82
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