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Search results 701 to 800 out of 848 for Htt

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Category: Publication
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Type Details Score
Publication
26908618 | J:233019
First Author: Mantovani S
Year: 2016
Journal: Hum Mol Genet
Title: Motor deficits associated with Huntington's disease occur in the absence of striatal degeneration in BACHD transgenic mice.
Volume: 25
Issue: 9
Pages: 1780-91
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Publication
38909878 | J:351005
 
First Author: Diaz Escarcega R
Year: 2024
Journal: Mol Cell Neurosci
Title: Sphingosine kinase 2 regulates protein ubiquitination networks in neurons.
Volume: 130
Pages: 103948
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Publication
36192390 | J:349950
First Author: Conroy F
Year: 2022
Journal: Nat Commun
Title: Chemical engineering of therapeutic siRNAs for allele-specific gene silencing in Huntington's disease models.
Volume: 13
Issue: 1
Pages: 5802
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Publication
33767215 | J:327806
First Author: Le Cann K
Year: 2021
Journal: Sci Rep
Title: The difficulty to model Huntington's disease in vitro using striatal medium spiny neurons differentiated from human induced pluripotent stem cells.
Volume: 11
Issue: 1
Pages: 6934
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Publication
23756199 | J:201703
 
First Author: Lee W
Year: 2013
Journal: Neurobiol Dis
Title: Enhanced Ca(2+)-dependent glutamate release from astrocytes of the BACHD Huntington's disease mouse model.
Volume: 58
Pages: 192-9
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Publication
26626081 | J:230901
 
First Author: Rocher AB
Year: 2016
Journal: Neurobiol Dis
Title: Synaptic scaling up in medium spiny neurons of aged BACHD mice: A slow-progression model of Huntington's disease.
Volume: 86
Pages: 131-9
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Publication
23697793 | J:199184
First Author: Hult Lundh S
Year: 2013
Journal: Hum Mol Genet
Title: Hypothalamic expression of mutant huntingtin contributes to the development of depressive-like behavior in the BAC transgenic mouse model of Huntington's disease.
Volume: 22
Issue: 17
Pages: 3485-97
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Publication
25740845 | J:221190
First Author: Mattis VB
Year: 2015
Journal: Hum Mol Genet
Title: HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicity.
Volume: 24
Issue: 11
Pages: 3257-71
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Publication
26807590 | J:251697
First Author: Schroeder AM
Year: 2016
Journal: PLoS One
Title: Cardiac Dysfunction in the BACHD Mouse Model of Huntington's Disease.
Volume: 11
Issue: 1
Pages: e0147269
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Publication
30802499 | J:281488
 
First Author: Radulescu CI
Year: 2019
Journal: Neurobiol Dis
Title: Manipulation of microbiota reveals altered callosal myelination and white matter plasticity in a model of Huntington disease.
Volume: 127
Pages: 65-75
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Publication
32422281 | J:299193
 
First Author: Gosset P
Year: 2020
Journal: Neurobiol Dis
Title: Evidence for the spread of human-derived mutant huntingtin protein in mice and non-human primates.
Volume: 141
Pages: 104941
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Publication
37090478 | J:348644
 
First Author: Duarte F
Year: 2023
Journal: Mol Ther Methods Clin Dev
Title: Semi-automated workflows to quantify AAV transduction in various brain areas and predict gene editing outcome for neurological disorders.
Volume: 29
Pages: 254-270
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Publication
16472649 | -
 
First Author: Baird D
Year: 2006
Journal: Methods Enzymol
Title: Biochemical characterization of the Cool (Cloned-out-of-Library)/Pix (Pak-interactive exchange factor) proteins.
Volume: 406
Pages: 58-69
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Publication
27206983 | J:237150
First Author: Kim SH
Year: 2016
Journal: Hum Mol Genet
Title: Allele-specific regulation of mutant Huntingtin by Wig1, a downstream target of p53.
Volume: 25
Issue: 12
Pages: 2514-2524
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Publication
35146388 | J:322625
First Author: Soylu-Kucharz R
Year: 2022
Journal: iScience
Title: IKKβ signaling mediates metabolic changes in the hypothalamus of a Huntington disease mouse model.
Volume: 25
Issue: 2
Pages: 103771
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Publication
18211820 | J:132665
First Author: Ichikawa M
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Expression analysis for inverted effects of serotonin transporter inactivation.
Volume: 368
Issue: 1
Pages: 43-9
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Publication
35044815 | J:355728
First Author: Powell JE
Year: 2022
Journal: Sci Adv
Title: Targeted gene silencing in the nervous system with CRISPR-Cas13.
Volume: 8
Issue: 3
Pages: eabk2485
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Publication
25038828 | J:232467
First Author: Fernández-Nogales M
Year: 2014
Journal: Nat Med
Title: Huntington's disease is a four-repeat tauopathy with tau nuclear rods.
Volume: 20
Issue: 8
Pages: 881-5
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Publication
29902468 | J:268498
 
First Author: Liu SY
Year: 2018
Journal: Brain Res
Title: Intravenous immunoglobulin ameliorates motor and cognitive deficits and neuropathology in R6/2 mouse model of Huntington's disease by decreasing mutant huntingtin protein level and normalizing NF-κB signaling pathway.
Volume: 1697
Pages: 21-33
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Publication
23275441 | J:316809
First Author: Lin JT
Year: 2013
Journal: Mol Cell Biol
Title: Regulation of feedback between protein kinase A and the proteasome system worsens Huntington's disease.
Volume: 33
Issue: 5
Pages: 1073-84
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Publication
29382760 | J:259830
First Author: Dargaei Z
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Restoring GABAergic inhibition rescues memory deficits in a Huntington's disease mouse model.
Volume: 115
Issue: 7
Pages: E1618-E1626
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Publication
32060489 | J:316242
First Author: Nakamori M
Year: 2020
Journal: Nat Genet
Title: A slipped-CAG DNA-binding small molecule induces trinucleotide-repeat contractions in vivo.
Volume: 52
Issue: 2
Pages: 146-159
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Publication
19591939 | J:155029
First Author: Li M
Year: 2009
Journal: Neurobiol Dis
Title: Y-27632 improves rotarod performance and reduces huntingtin levels in R6/2 mice.
Volume: 36
Issue: 3
Pages: 413-20
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Publication
27146268 | J:239573
First Author: Ochaba J
Year: 2016
Journal: Neuron
Title: PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington's Disease-Associated Phenotypes In Vivo.
Volume: 90
Issue: 3
Pages: 507-20
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Publication
37407555 | J:354247
First Author: Ferlazzo GM
Year: 2023
Journal: Nat Commun
Title: Genome-wide screening in pluripotent cells identifies Mtf1 as a suppressor of mutant huntingtin toxicity.
Volume: 14
Issue: 1
Pages: 3962
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Publication
20670829 | J:167868
First Author: Miller JP
Year: 2010
Journal: Neuron
Title: Matrix metalloproteinases are modifiers of huntingtin proteolysis and toxicity in Huntington's disease.
Volume: 67
Issue: 2
Pages: 199-212
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Publication
20147317 | J:158714
First Author: Crittenden JR
Year: 2010
Journal: Hum Mol Genet
Title: CalDAG-GEFI down-regulation in the striatum as a neuroprotective change in Huntington's disease.
Volume: 19
Issue: 9
Pages: 1756-65
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Publication
15837560 | J:116299
First Author: Miller TW
Year: 2005
Journal: Neurobiol Dis
Title: A human single-chain Fv intrabody preferentially targets amino-terminal Huntingtin's fragments in striatal models of Huntington's disease.
Volume: 19
Issue: 1-2
Pages: 47-56
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Publication
24836077 | J:212904
First Author: Yano H
Year: 2014
Journal: Nat Neurosci
Title: Inhibition of mitochondrial protein import by mutant huntingtin.
Volume: 17
Issue: 6
Pages: 822-31
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Publication
15911879 | J:99654
First Author: Luo S
Year: 2005
Journal: J Cell Biol
Title: Cdk5 phosphorylation of huntingtin reduces its cleavage by caspases: implications for mutant huntingtin toxicity.
Volume: 169
Issue: 4
Pages: 647-56
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Publication
22786682 | J:186693
First Author: Tsunemi T
Year: 2012
Journal: Sci Transl Med
Title: PGC-1α rescues Huntington's disease proteotoxicity by preventing oxidative stress and promoting TFEB function.
Volume: 4
Issue: 142
Pages: 142ra97
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Publication
17276692 | J:119003
First Author: Van Raamsdonk JM
Year: 2007
Journal: Neurobiol Dis
Title: Phenotypic abnormalities in the YAC128 mouse model of Huntington disease are penetrant on multiple genetic backgrounds and modulated by strain.
Volume: 26
Issue: 1
Pages: 189-200
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Publication
32814053 | J:296126
First Author: Haenig C
Year: 2020
Journal: Cell Rep
Title: Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Volume: 32
Issue: 7
Pages: 108050
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Publication
6202816 | J:7457
First Author: Klyczek KK
Year: 1984
Journal: J Exp Med
Title: T cell surface I-J glycoprotein. Concerted action of chromosome-4 and -17 genes forms an epitope dependent on alpha-D-mannosyl residues.
Volume: 159
Issue: 6
Pages: 1604-17
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9459551 | J:45104
First Author: Bengel D
Year: 1997
Journal: Brain Res
Title: Cellular localization and expression of the serotonin transporter in mouse brain.
Volume: 778
Issue: 2
Pages: 338-45
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19259385 | J:149845
First Author: Ehrnhoefer DE
Year: 2009
Journal: Dis Model Mech
Title: Mouse models of Huntington disease: variations on a theme.
Volume: 2
Issue: 3-4
Pages: 123-9
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Publication
24412373 | J:207987
 
First Author: Sancho M
Year: 2014
Journal: Neuroscience
Title: Inactivation of Apaf1 reduces the formation of mutant huntingtin-dependent aggregates and cell death.
Volume: 262
Pages: 83-91
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Publication
21088884 | -
First Author: Momboisse F
Year: 2010
Journal: Cell Mol Neurobiol
Title: The Rho guanine nucleotide exchange factors Intersectin 1L and β-Pix control calcium-regulated exocytosis in neuroendocrine PC12 cells.
Volume: 30
Issue: 8
Pages: 1327-33
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Publication
21472000 | -
First Author: Legg K
Year: 2011
Journal: Nat Rev Mol Cell Biol
Title: Cell migration: keeping young and mobile with β-PIX.
Volume: 12
Issue: 5
Pages: 278
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Publication
22114281 | -
First Author: Sun Y
Year: 2011
Journal: J Neurosci
Title: β-Pix modulates actin-mediated recruitment of synaptic vesicles to synapses.
Volume: 31
Issue: 47
Pages: 17123-33
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Publication
22087847 | -
First Author: Koh SH
Year: 2012
Journal: Stem Cells Dev
Title: β-PIX is critical for transplanted mesenchymal stromal cell migration.
Volume: 21
Issue: 11
Pages: 1989-99
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21828338 | J:182176
First Author: Kepner EM
Year: 2011
Journal: Am J Physiol Endocrinol Metab
Title: Cool-1/βPIX functions as a guanine nucleotide exchange factor in the cycling of Cdc42 to regulate insulin secretion.
Volume: 301
Issue: 6
Pages: E1072-80
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Publication
35379852 | J:325581
First Author: Santos RPM
Year: 2022
Journal: Sci Rep
Title: Metabotropic glutamate receptor 5 knockout rescues obesity phenotype in a mouse model of Huntington's disease.
Volume: 12
Issue: 1
Pages: 5621
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Publication
35643779 | J:325700
First Author: de Souza JM
Year: 2022
Journal: Sci Rep
Title: mGluR5 ablation leads to age-related synaptic plasticity impairments and does not improve Huntington's disease phenotype.
Volume: 12
Issue: 1
Pages: 8982
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Publication
30930274 | J:285631
 
First Author: Carvalho TG
Year: 2019
Journal: Neurochem Int
Title: Metabotropic glutamate receptor 5 ablation accelerates age-related neurodegeneration and neuroinflammation.
Volume: 126
Pages: 218-228
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Publication
28821675 | J:248996
First Author: Yang Y
Year: 2017
Journal: J Neurosci
Title: Synergistic Toxicity of Polyglutamine-Expanded TATA-Binding Protein in Glia and Neuronal Cells: Therapeutic Implications for Spinocerebellar Ataxia 17.
Volume: 37
Issue: 38
Pages: 9101-9115
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Publication
15836623 | J:174269
First Author: Kotliarova S
Year: 2005
Journal: J Neurochem
Title: Decreased expression of hypothalamic neuropeptides in Huntington disease transgenic mice with expanded polyglutamine-EGFP fluorescent aggregates.
Volume: 93
Issue: 3
Pages: 641-53
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Publication
20152125 | J:167657
First Author: Milnerwood AJ
Year: 2010
Journal: Neuron
Title: Early increase in extrasynaptic NMDA receptor signaling and expression contributes to phenotype onset in Huntington's disease mice.
Volume: 65
Issue: 2
Pages: 178-90
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Publication
18854207 | J:144587
First Author: Spampanato J
Year: 2008
Journal: Neuroscience
Title: Progressive synaptic pathology of motor cortical neurons in a BAC transgenic mouse model of Huntington's disease.
Volume: 157
Issue: 3
Pages: 606-20
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Publication
32387649 | J:292685
 
First Author: King AC
Year: 2020
Journal: Exp Neurol
Title: Differential effects of SNARE-dependent gliotransmission on behavioral phenotypes in a mouse model of Huntington's disease.
Volume: 330
Pages: 113358
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Publication
22328089 | J:183804
First Author: Pouladi MA
Year: 2012
Journal: Hum Mol Genet
Title: Marked differences in neurochemistry and aggregates despite similar behavioural and neuropathological features of Huntington disease in the full-length BACHD and YAC128 mice.
Volume: 21
Issue: 10
Pages: 2219-32
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Publication
17928447 | J:125695
First Author: Parker JA
Year: 2007
Journal: J Neurosci
Title: Huntingtin-interacting protein 1 influences worm and mouse presynaptic function and protects Caenorhabditis elegans neurons against mutant polyglutamine toxicity.
Volume: 27
Issue: 41
Pages: 11056-64
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Publication
15379999 | J:101292
First Author: Tang TS
Year: 2004
Journal: Eur J Neurosci
Title: HAP1 facilitates effects of mutant huntingtin on inositol 1,4,5-trisphosphate-induced Ca release in primary culture of striatal medium spiny neurons.
Volume: 20
Issue: 7
Pages: 1779-87
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Publication
18753376 | J:138790
First Author: Kaminosono S
Year: 2008
Journal: J Neurosci
Title: Suppression of mutant Huntingtin aggregate formation by Cdk5/p35 through the effect on microtubule stability.
Volume: 28
Issue: 35
Pages: 8747-55
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Publication
22127389 | J:182049
First Author: Roux JC
Year: 2012
Journal: Neurobiol Dis
Title: Modification of Mecp2 dosage alters axonal transport through the Huntingtin/Hap1 pathway.
Volume: 45
Issue: 2
Pages: 786-95
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12968128 | J:134102
First Author: Holmes A
Year: 2003
Journal: Neuropsychopharmacology
Title: Mice lacking the serotonin transporter exhibit 5-HT(1A) receptor-mediated abnormalities in tests for anxiety-like behavior.
Volume: 28
Issue: 12
Pages: 2077-88
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Publication
16595660 | J:113725
First Author: Qiu Z
Year: 2006
Journal: J Biol Chem
Title: Sp1 is up-regulated in cellular and transgenic models of Huntington disease, and its reduction is neuroprotective.
Volume: 281
Issue: 24
Pages: 16672-80
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Publication
19605647 | J:151692
First Author: Wacker JL
Year: 2009
Journal: J Neurosci
Title: Loss of Hsp70 exacerbates pathogenesis but not levels of fibrillar aggregates in a mouse model of Huntington's disease.
Volume: 29
Issue: 28
Pages: 9104-14
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Publication
22383888 | J:183404
First Author: Bañez-Coronel M
Year: 2012
Journal: PLoS Genet
Title: A pathogenic mechanism in Huntington's disease involves small CAG-repeated RNAs with neurotoxic activity.
Volume: 8
Issue: 2
Pages: e1002481
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19759302 | J:152762
First Author: Dai Y
Year: 2009
Journal: J Neurosci
Title: Striatal expression of a calmodulin fragment improved motor function, weight loss, and neuropathology in the R6/2 mouse model of Huntington's disease.
Volume: 29
Issue: 37
Pages: 11550-9
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Publication
29860423 | J:264283
First Author: Couly S
Year: 2018
Journal: Hum Mol Genet
Title: Improvement of BDNF signalling by P42 peptide in Huntington's disease.
Volume: 27
Issue: 17
Pages: 3012-3028
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Publication
28182673 | J:248017
First Author: Datson NA
Year: 2017
Journal: PLoS One
Title: The expanded CAG repeat in the huntingtin gene as target for therapeutic RNA modulation throughout the HD mouse brain.
Volume: 12
Issue: 2
Pages: e0171127
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Publication
31465962 | J:285519
 
First Author: Ekman FK
Year: 2019
Journal: Mol Ther Nucleic Acids
Title: CRISPR-Cas9-Mediated Genome Editing Increases Lifespan and Improves Motor Deficits in a Huntington's Disease Mouse Model.
Volume: 17
Pages: 829-839
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Publication
22848498 | J:189704
First Author: Gong B
Year: 2012
Journal: PLoS One
Title: Temporal separation of aggregation and ubiquitination during early inclusion formation in transgenic mice carrying the Huntington's disease mutation.
Volume: 7
Issue: 7
Pages: e41450
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Publication
33420088 | J:300300
First Author: Kumar MJV
Year: 2021
Journal: Sci Rep
Title: Spatiotemporal analysis of soluble aggregates and autophagy markers in the R6/2 mouse model.
Volume: 11
Issue: 1
Pages: 96
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25271153 | J:218102
First Author: Kannike K
Year: 2014
Journal: J Biol Chem
Title: Forkhead transcription factor FOXO3a levels are increased in Huntington disease because of overactivated positive autofeedback loop.
Volume: 289
Issue: 47
Pages: 32845-57
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21651979 | J:177625
First Author: Chiang MC
Year: 2011
Journal: Biochim Biophys Acta
Title: The dysfunction of hepatic transcriptional factors in mice with Huntington's Disease.
Volume: 1812
Issue: 9
Pages: 1111-20
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20668093 | J:164450
First Author: Chiang MC
Year: 2010
Journal: Hum Mol Genet
Title: Modulation of energy deficiency in Huntington's disease via activation of the peroxisome proliferator-activated receptor gamma.
Volume: 19
Issue: 20
Pages: 4043-58
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21217767 | J:186963
First Author: Richards P
Year: 2011
Journal: Cell Death Differ
Title: Dendritic spine loss and neurodegeneration is rescued by Rab11 in models of Huntington's disease.
Volume: 18
Issue: 2
Pages: 191-200
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Publication
30279997 | J:284917
   
First Author: Cha MY
Year: 2018
Journal: PLoS Curr
Title: Removal of the Mitochondrial Fission Factor Mff Exacerbates Neuronal Loss and Neurological Phenotypes in a Huntington's Disease Mouse Model.
Volume: 10
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32622701 | J:297610
 
First Author: Skotte NH
Year: 2020
Journal: Exp Neurol
Title: Compromised IGF signaling causes caspase-6 activation in Huntington disease.
Volume: 332
Pages: 113396
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Publication
22187438 | J:184100
First Author: Gupta S
Year: 2012
Journal: J Biol Chem
Title: Protein misfolding detected early in pathogenesis of transgenic mouse model of Huntington disease using amyloid seeding assay.
Volume: 287
Issue: 13
Pages: 9982-9
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23409115 | J:198315
First Author: Li M
Year: 2013
Journal: PLoS One
Title: Intravitreal administration of HA-1077, a ROCK inhibitor, improves retinal function in a mouse model of huntington disease.
Volume: 8
Issue: 2
Pages: e56026
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Publication
32702387 | J:300561
 
First Author: Rolfes S
Year: 2020
Journal: Neurobiol Dis
Title: Lentiviral delivery of human erythropoietin attenuates hippocampal atrophy and improves cognition in the R6/2 mouse model of Huntington's disease.
Volume: 144
Pages: 105024
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16326808 | J:104367
First Author: Jin K
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: FGF-2 promotes neurogenesis and neuroprotection and prolongs survival in a transgenic mouse model of Huntington's disease.
Volume: 102
Issue: 50
Pages: 18189-94
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24670645 | J:210468
First Author: Paul BD
Year: 2014
Journal: Nature
Title: Cystathionine γ-lyase deficiency mediates neurodegeneration in Huntington's disease.
Volume: 509
Issue: 7498
Pages: 96-100
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23416527 | J:202434
First Author: Lin YS
Year: 2013
Journal: Biochim Biophys Acta
Title: Enhancement of brain-type creatine kinase activity ameliorates neuronal deficits in Huntington's disease.
Volume: 1832
Issue: 6
Pages: 742-53
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23796713 | J:205328
First Author: Das E
Year: 2013
Journal: Biochem Biophys Res Commun
Title: MicroRNA-124 targets CCNA2 and regulates cell cycle in STHdh(Q111)/Hdh(Q111) cells.
Volume: 437
Issue: 2
Pages: 217-24
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37446028 | J:348697
 
First Author: Arancibia-Opazo S
Year: 2023
Journal: Int J Mol Sci
Title: Transcriptional and Histone Acetylation Changes Associated with CRE Elements Expose Key Factors Governing the Regulatory Circuit in the Early Stage of Huntington's Disease Models.
Volume: 24
Issue: 13
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Publication
23392662 | J:327891
First Author: Taylor DM
Year: 2013
Journal: J Neurosci
Title: MAP kinase phosphatase 1 (MKP-1/DUSP1) is neuroprotective in Huntington's disease via additive effects of JNK and p38 inhibition.
Volume: 33
Issue: 6
Pages: 2313-25
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Publication
28263187 | J:243373
First Author: Tanaka M
Year: 2017
Journal: J Clin Invest
Title: Aggregation of scaffolding protein DISC1 dysregulates phosphodiesterase 4 in Huntington's disease.
Volume: 127
Issue: 4
Pages: 1438-1450
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Publication
24475300 | J:212703
First Author: Safren N
Year: 2014
Journal: PLoS One
Title: Ubiquilin-1 overexpression increases the lifespan and delays accumulation of Huntingtin aggregates in the R6/2 mouse model of Huntington's disease.
Volume: 9
Issue: 1
Pages: e87513
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Publication
32898606 | J:311428
 
First Author: Pierzynowska K
Year: 2021
Journal: Gene
Title: Hair dysmorphology in the R6/1 and R6/2 mouse models of Huntington's disease.
Volume: 765
Pages: 145133
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Publication
28213125 | J:255616
First Author: Bichell TJV
Year: 2017
Journal: Biochim Biophys Acta
Title: Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington's disease mouse model.
Volume: 1863
Issue: 6
Pages: 1596-1604
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Publication
24634145 | J:210980
First Author: Lim NK
Year: 2014
Journal: Hum Mol Genet
Title: Localized changes to glycogen synthase kinase-3 and collapsin response mediator protein-2 in the Huntington's disease affected brain.
Volume: 23
Issue: 15
Pages: 4051-63
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