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Search results 801 to 900 out of 1012 for Atm

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Category: Publication
Type Details Score
Publication
First Author: Cortez D
Year: 2001
Journal: Science
Title: ATR and ATRIP: partners in checkpoint signaling.
Volume: 294
Issue: 5547
Pages: 1713-6
Publication
First Author: Yuan Z
Year: 2007
Journal: Mol Cell
Title: SIRT1 regulates the function of the Nijmegen breakage syndrome protein.
Volume: 27
Issue: 1
Pages: 149-62
Publication
First Author: Zhang Q
Year: 2016
Journal: Mol Cell
Title: FBXW7 Facilitates Nonhomologous End-Joining via K63-Linked Polyubiquitylation of XRCC4.
Volume: 61
Issue: 3
Pages: 419-433
Publication
First Author: Rotman G
Year: 1998
Journal: Hum Mol Genet
Title: ATM: from gene to function.
Volume: 7
Issue: 10
Pages: 1555-63
Publication  
First Author: Zhou BB
Year: 2003
Journal: Methods Mol Biol
Title: Role of tumor suppressors in DNA damage response.
Volume: 223
Pages: 39-50
Publication
First Author: Wang X
Year: 2004
Journal: Nucleic Acids Res
Title: Involvement of Hus1 in the chain elongation step of DNA replication after exposure to camptothecin or ionizing radiation.
Volume: 32
Issue: 2
Pages: 767-75
Publication
First Author: Toledo LI
Year: 2008
Journal: Genes Dev
Title: ATR signaling can drive cells into senescence in the absence of DNA breaks.
Volume: 22
Issue: 3
Pages: 297-302
Publication
First Author: Iwabuchi K
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Characterization of a cancer cell line that expresses a splicing variant form of 53BP1: separation of checkpoint and repair functions in 53BP1.
Volume: 376
Issue: 3
Pages: 509-13
Publication
First Author: Pontano LL
Year: 2008
Journal: Mol Cell Biol
Title: Genotoxic stress-induced cyclin D1 phosphorylation and proteolysis are required for genomic stability.
Volume: 28
Issue: 23
Pages: 7245-58
Publication
First Author: Volonte D
Year: 2009
Journal: J Biol Chem
Title: Caveolin-1 expression is required for the development of pulmonary emphysema through activation of the ATM-p53-p21 pathway.
Volume: 284
Issue: 9
Pages: 5462-6
Publication
First Author: Kumar A
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Nuclear phosphoinositide 3-kinase beta controls double-strand break DNA repair.
Volume: 107
Issue: 16
Pages: 7491-6
Publication
First Author: Ginjala V
Year: 2011
Journal: Mol Cell Biol
Title: BMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repair.
Volume: 31
Issue: 10
Pages: 1972-82
Publication
First Author: Assaily W
Year: 2011
Journal: Mol Cell
Title: ROS-mediated p53 induction of Lpin1 regulates fatty acid oxidation in response to nutritional stress.
Volume: 44
Issue: 3
Pages: 491-501
Publication
First Author: Liu Y
Year: 2011
Journal: Cell Death Differ
Title: Proapoptotic Bid mediates the Atr-directed DNA damage response to replicative stress.
Volume: 18
Issue: 5
Pages: 841-52
Publication
First Author: Li M
Year: 2013
Journal: Genes Dev
Title: The FHA and BRCT domains recognize ADP-ribosylation during DNA damage response.
Volume: 27
Issue: 16
Pages: 1752-68
Publication
First Author: Zhang P
Year: 2014
Journal: Nat Cell Biol
Title: ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1.
Volume: 16
Issue: 9
Pages: 864-75
Publication
First Author: Kraakman MJ
Year: 2015
Journal: Cell Metab
Title: Blocking IL-6 trans-signaling prevents high-fat diet-induced adipose tissue macrophage recruitment but does not improve insulin resistance.
Volume: 21
Issue: 3
Pages: 403-16
Publication
First Author: Kang C
Year: 2015
Journal: Science
Title: The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4.
Volume: 349
Issue: 6255
Pages: aaa5612
Publication
First Author: Kibe T
Year: 2016
Journal: Mol Cell
Title: TPP1 Blocks an ATR-Mediated Resection Mechanism at Telomeres.
Volume: 61
Issue: 2
Pages: 236-46
Publication  
First Author: Li Z
Year: 2017
Journal: Mol Cell Biol
Title: DNA Damage Response-Independent Role for MDC1 in Maintaining Genomic Stability.
Volume: 37
Issue: 9
Publication
First Author: Connolly PF
Year: 2016
Journal: FEBS J
Title: DNA-PK activity is associated with caspase-dependent myogenic differentiation.
Volume: 283
Issue: 19
Pages: 3626-3636
Publication
First Author: Shan B
Year: 2017
Journal: Nat Immunol
Title: The metabolic ER stress sensor IRE1α suppresses alternative activation of macrophages and impairs energy expenditure in obesity.
Volume: 18
Issue: 5
Pages: 519-529
Publication
First Author: Van Ly D
Year: 2018
Journal: Mol Cell
Title: Telomere Loop Dynamics in Chromosome End Protection.
Volume: 71
Issue: 4
Pages: 510-525.e6
Publication
First Author: Leem J
Year: 2018
Journal: Biol Reprod
Title: WIP1 phosphatase suppresses the DNA damage response during G2/prophase arrest in mouse oocytes.
Volume: 99
Issue: 4
Pages: 798-805
Publication
First Author: Colomer C
Year: 2019
Journal: Mol Cell
Title: IKKα Kinase Regulates the DNA Damage Response and Drives Chemo-resistance in Cancer.
Volume: 75
Issue: 4
Pages: 669-682.e5
Publication
First Author: Cui D
Year: 2020
Journal: Cell Rep
Title: FBXW7 Confers Radiation Survival by Targeting p53 for Degradation.
Volume: 30
Issue: 2
Pages: 497-509.e4
Publication  
First Author: Sorimachi Y
Year: 2021
Journal: J Biol Chem
Title: p38α plays differential roles in hematopoietic stem cell activity dependent on aging contexts.
Volume: 296
Pages: 100563
Publication
First Author: Yamada S
Year: 2020
Journal: Genes Dev
Title: Molecular structures and mechanisms of DNA break processing in mouse meiosis.
Volume: 34
Issue: 11-12
Pages: 806-818
Publication  
First Author: Yan Q
Year: 2022
Journal: Front Cell Dev Biol
Title: CTLA-4 Facilitates DNA Damage-Induced Apoptosis by Interacting With PP2A.
Volume: 10
Pages: 728771
Publication
First Author: Lam YC
Year: 2010
Journal: EMBO J
Title: SNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repair.
Volume: 29
Issue: 13
Pages: 2230-41
Publication
First Author: de Klein A
Year: 2000
Journal: Curr Biol
Title: Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice.
Volume: 10
Issue: 8
Pages: 479-82
Publication
First Author: Brown EJ
Year: 2003
Journal: Genes Dev
Title: Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance.
Volume: 17
Issue: 5
Pages: 615-28
Publication  
First Author: García-González R
Year: 2020
Journal: Cancers (Basel)
Title: VRK1 Phosphorylates Tip60/KAT5 and Is Required for H4K16 Acetylation in Response to DNA Damage.
Volume: 12
Issue: 10
Publication
First Author: Sapkota GP
Year: 2002
Journal: Biochem J
Title: Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366.
Volume: 368
Issue: Pt 2
Pages: 507-16
Publication
First Author: Kikuchi K
Year: 2013
Journal: Oncogene
Title: Protein kinase C iota as a therapeutic target in alveolar rhabdomyosarcoma.
Volume: 32
Issue: 3
Pages: 286-95
Publication  
First Author: Sawaki D
Year: 2023
Journal: JCI Insight
Title: Osteopontin promotes age-related adipose tissue remodeling through senescence-associated macrophage dysfunction.
Volume: 8
Issue: 8
Publication
First Author: Hwang I
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: GABA-stimulated adipose-derived stem cells suppress subcutaneous adipose inflammation in obesity.
Volume: 116
Issue: 24
Pages: 11936-11945
Publication
First Author: Prieur X
Year: 2011
Journal: Diabetes
Title: Differential lipid partitioning between adipocytes and tissue macrophages modulates macrophage lipotoxicity and M2/M1 polarization in obese mice.
Volume: 60
Issue: 3
Pages: 797-809
Publication
First Author: Kitade H
Year: 2012
Journal: Diabetes
Title: CCR5 plays a critical role in obesity-induced adipose tissue inflammation and insulin resistance by regulating both macrophage recruitment and M1/M2 status.
Volume: 61
Issue: 7
Pages: 1680-90
Publication
First Author: Aouadi M
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: Lipid storage by adipose tissue macrophages regulates systemic glucose tolerance.
Volume: 307
Issue: 4
Pages: E374-83
Publication
First Author: Grijalva A
Year: 2016
Journal: Diabetes
Title: Autophagy Is Dispensable for Macrophage-Mediated Lipid Homeostasis in Adipose Tissue.
Volume: 65
Issue: 4
Pages: 967-80
Publication
First Author: Gabriel TL
Year: 2017
Journal: PLoS One
Title: Induction of Sphk1 activity in obese adipose tissue macrophages promotes survival.
Volume: 12
Issue: 7
Pages: e0182075
Publication
First Author: Lee YS
Year: 2012
Journal: Diabetologia
Title: Glucagon-like peptide-1 inhibits adipose tissue macrophage infiltration and inflammation in an obese mouse model of diabetes.
Volume: 55
Issue: 9
Pages: 2456-68
Publication
First Author: Ghorpade DS
Year: 2018
Journal: Nature
Title: Hepatocyte-secreted DPP4 in obesity promotes adipose inflammation and insulin resistance.
Volume: 555
Issue: 7698
Pages: 673-677
Publication
First Author: Kayali R
Year: 2012
Journal: Hum Mol Genet
Title: Read-through compound 13 restores dystrophin expression and improves muscle function in the mdx mouse model for Duchenne muscular dystrophy.
Volume: 21
Issue: 18
Pages: 4007-20
Publication
First Author: Zheng S
Year: 2018
Journal: Cell Death Dis
Title: DZNep inhibits H3K27me3 deposition and delays retinal degeneration in the rd1 mice.
Volume: 9
Issue: 3
Pages: 310
Publication  
First Author: Hams E
Year: 2020
Journal: Front Immunol
Title: Role for Retinoic Acid-Related Orphan Receptor Alpha (RORα) Expressing Macrophages in Diet-Induced Obesity.
Volume: 11
Pages: 1966
Publication
First Author: Konishi A
Year: 2008
Journal: Genes Dev
Title: Cell cycle control of telomere protection and NHEJ revealed by a ts mutation in the DNA-binding domain of TRF2.
Volume: 22
Issue: 9
Pages: 1221-30
Publication
First Author: Whang YE
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: c-Abl is required for development and optimal cell proliferation in the context of p53 deficiency.
Volume: 97
Issue: 10
Pages: 5486-91
Publication
First Author: Wei G
Year: 2008
Journal: Cancer Res
Title: Elevated ornithine decarboxylase levels activate ataxia telangiectasia mutated-DNA damage signaling in normal keratinocytes.
Volume: 68
Issue: 7
Pages: 2214-22
Publication  
First Author: Wang XS
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: DNA damage-induced phosphorylation of CtIP at a conserved ATM/ATR site T855 promotes lymphomagenesis in mice.
Volume: 118
Issue: 38
Publication
First Author: Martínez P
Year: 2009
Journal: Genes Dev
Title: Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice.
Volume: 23
Issue: 17
Pages: 2060-75
Publication
First Author: Chesnokova V
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: p21(Cip1) restrains pituitary tumor growth.
Volume: 105
Issue: 45
Pages: 17498-503
Publication
First Author: Ayrault O
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Inhibition of Hsp90 via 17-DMAG induces apoptosis in a p53-dependent manner to prevent medulloblastoma.
Volume: 106
Issue: 40
Pages: 17037-42
Publication
First Author: Sluss HK
Year: 2004
Journal: Mol Cell Biol
Title: Phosphorylation of serine 18 regulates distinct p53 functions in mice.
Volume: 24
Issue: 3
Pages: 976-84
Publication
First Author: Liu DP
Year: 2010
Journal: Oncogene
Title: A common gain of function of p53 cancer mutants in inducing genetic instability.
Volume: 29
Issue: 7
Pages: 949-56
Publication
First Author: Saleh AD
Year: 2011
Journal: PLoS One
Title: Cellular stress induced alterations in microRNA let-7a and let-7b expression are dependent on p53.
Volume: 6
Issue: 10
Pages: e24429
Publication
First Author: Sepe S
Year: 2022
Journal: EMBO Rep
Title: DNA damage response at telomeres boosts the transcription of SARS-CoV-2 receptor ACE2 during aging.
Volume: 23
Issue: 2
Pages: e53658
Publication
First Author: McNees CJ
Year: 2010
Journal: J Cell Biol
Title: ATR suppresses telomere fragility and recombination but is dispensable for elongation of short telomeres by telomerase.
Volume: 188
Issue: 5
Pages: 639-52
Publication
First Author: Burma S
Year: 1999
Journal: J Biol Chem
Title: DNA-dependent protein kinase-independent activation of p53 in response to DNA damage.
Volume: 274
Issue: 24
Pages: 17139-43
Publication
First Author: Lin CP
Year: 2008
Journal: J Biol Chem
Title: A ubiquitin-proteasome pathway for the repair of topoisomerase I-DNA covalent complexes.
Volume: 283
Issue: 30
Pages: 21074-83
Publication
First Author: Nance SA
Year: 2023
Journal: Sci Rep
Title: MSR1 is not required for obesity-associated inflammation and insulin resistance in mice.
Volume: 13
Issue: 1
Pages: 2651
Publication
First Author: Orr JS
Year: 2012
Journal: Diabetes
Title: Toll-like receptor 4 deficiency promotes the alternative activation of adipose tissue macrophages.
Volume: 61
Issue: 11
Pages: 2718-27
Publication
First Author: Xiang W
Year: 2020
Journal: Signal Transduct Target Ther
Title: Dietary fats suppress the peritoneal seeding of colorectal cancer cells through the TLR4/Cxcl10 axis in adipose tissue macrophages.
Volume: 5
Issue: 1
Pages: 239
Publication
First Author: Le Toriellec E
Year: 2008
Journal: Blood
Title: Haploinsufficiency of CDKN1B contributes to leukemogenesis in T-cell prolymphocytic leukemia.
Volume: 111
Issue: 4
Pages: 2321-8
Publication
First Author: Zhu Y
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Phosphorylation of DNA-PKcs at the S2056 cluster ensures efficient and productive lymphocyte development in XLF-deficient mice.
Volume: 120
Issue: 25
Pages: e2221894120
Publication
First Author: Martínez P
Year: 2012
Journal: J Cell Biol
Title: 53BP1 deficiency combined with telomere dysfunction activates ATR-dependent DNA damage response.
Volume: 197
Issue: 2
Pages: 283-300
Publication
First Author: Abe H
Year: 2018
Journal: Hum Mol Genet
Title: CHEK1 coordinates DNA damage signaling and meiotic progression in the male germline of mice.
Volume: 27
Issue: 7
Pages: 1136-1149
Publication
First Author: Toyoshima M
Year: 2005
Journal: Oncogene
Title: Transcription-independent suppression of DNA synthesis by p53 in sperm-irradiated mouse zygotes.
Volume: 24
Issue: 20
Pages: 3229-35
Publication
First Author: Hao Z
Year: 2012
Journal: J Exp Med
Title: The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis.
Volume: 209
Issue: 1
Pages: 173-86
Publication
First Author: Bidany-Mizrahi T
Year: 2024
Journal: Cell Death Discov
Title: Unveiling the relationship between WWOX and BRCA1 in mammary tumorigenicity and in DNA repair pathway selection.
Volume: 10
Issue: 1
Pages: 145
Publication
First Author: Sharma M
Year: 2020
Journal: Sci Rep
Title: Enhanced glycolysis and HIF-1α activation in adipose tissue macrophages sustains local and systemic interleukin-1β production in obesity.
Volume: 10
Issue: 1
Pages: 5555
Publication
First Author: Blaszczak AM
Year: 2019
Journal: J Immunol
Title: Loss of Antigen Presentation in Adipose Tissue Macrophages or in Adipocytes, but Not Both, Improves Glucose Metabolism.
Volume: 202
Issue: 8
Pages: 2451-2459
Publication
First Author: Gavin KM
Year: 2021
Journal: Adipocyte
Title: Hematopoietic stem cells produce intermediate lineage adipocyte progenitors that simultaneously express both myeloid and mesenchymal lineage markers in adipose tissue.
Volume: 10
Issue: 1
Pages: 394-407
Publication
First Author: Dahik VD
Year: 2024
Journal: Sci Transl Med
Title: ABCG1 orchestrates adipose tissue macrophage plasticity and insulin resistance in obesity by rewiring saturated fatty acid pools.
Volume: 16
Issue: 777
Pages: eadi6682
Publication  
First Author: Gao H
Year: 2021
Journal: Cells
Title: Adipose Tissue Macrophages Modulate Obesity-Associated β Cell Adaptations through Secreted miRNA-Containing Extracellular Vesicles.
Volume: 10
Issue: 9
Publication
First Author: Kawano Y
Year: 2012
Journal: Diabetes
Title: Loss of Pdk1-Foxo1 signaling in myeloid cells predisposes to adipose tissue inflammation and insulin resistance.
Volume: 61
Issue: 8
Pages: 1935-48
Publication
First Author: Feng T
Year: 2022
Journal: Nat Commun
Title: Adipocyte-derived lactate is a signalling metabolite that potentiates adipose macrophage inflammation via targeting PHD2.
Volume: 13
Issue: 1
Pages: 5208
Publication
First Author: Wang X
Year: 2016
Journal: JCI Insight
Title: Epigenetic regulation of macrophage polarization and inflammation by DNA methylation in obesity.
Volume: 1
Issue: 19
Pages: e87748
Publication
First Author: Hansen RK
Year: 2016
Journal: Nat Cell Biol
Title: SCAI promotes DNA double-strand break repair in distinct chromosomal contexts.
Volume: 18
Issue: 12
Pages: 1357-1366
Publication
First Author: Kumar R
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Purkinje cell-specific males absent on the first (mMof) gene deletion results in an ataxia-telangiectasia-like neurological phenotype and backward walking in mice.
Volume: 108
Issue: 9
Pages: 3636-41
Publication
First Author: Larijani M
Year: 2005
Journal: Nucleic Acids Res
Title: Lack of MSH2 involvement differentiates V(D)J recombination from other non-homologous end joining events.
Volume: 33
Issue: 21
Pages: 6733-42
Publication
First Author: Lin SJ
Year: 2014
Journal: Carcinogenesis
Title: TR4 nuclear receptor functions as a tumor suppressor for prostate tumorigenesis via modulation of DNA damage/repair system.
Volume: 35
Issue: 6
Pages: 1399-406
Publication
First Author: Lumeng CN
Year: 2008
Journal: Diabetes
Title: Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes.
Volume: 57
Issue: 12
Pages: 3239-46
Publication
First Author: Maryanovich M
Year: 2012
Journal: Nat Cell Biol
Title: The ATM-BID pathway regulates quiescence and survival of haematopoietic stem cells.
Volume: 14
Issue: 5
Pages: 535-41
Publication
First Author: Oh DY
Year: 2012
Journal: Diabetes
Title: Increased macrophage migration into adipose tissue in obese mice.
Volume: 61
Issue: 2
Pages: 346-54
Publication
First Author: Pao GM
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Role of BRCA1 in brain development.
Volume: 111
Issue: 13
Pages: E1240-8
Publication  
First Author: Ganesan S
Year: 2016
Journal: Toxicol Appl Pharmacol
Title: The ovarian DNA damage repair response is induced prior to phosphoramide mustard-induced follicle depletion, and ataxia telangiectasia mutated inhibition prevents PM-induced follicle depletion.
Volume: 292
Pages: 65-74
Publication
First Author: Lisi S
Year: 2011
Journal: Diabetes
Title: Obesity-associated hepatosteatosis and impairment of glucose homeostasis are attenuated by haptoglobin deficiency.
Volume: 60
Issue: 10
Pages: 2496-505
Publication
First Author: Li X
Year: 2010
Journal: Mol Cell Biol
Title: MOF and H4 K16 acetylation play important roles in DNA damage repair by modulating recruitment of DNA damage repair protein Mdc1.
Volume: 30
Issue: 22
Pages: 5335-47
Publication
First Author: Kang J
Year: 2002
Journal: EMBO J
Title: Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair.
Volume: 21
Issue: 6
Pages: 1447-55
Publication
First Author: Kim SY
Year: 2019
Journal: Cell Death Differ
Title: Transient inhibition of p53 homologs protects ovarian function from two distinct apoptotic pathways triggered by anticancer therapies.
Volume: 26
Issue: 3
Pages: 502-515
Publication
First Author: Zheng L
Year: 2008
Journal: Blood
Title: TLR9 engagement on CD4 T lymphocytes represses gamma-radiation-induced apoptosis through activation of checkpoint kinase response elements.
Volume: 111
Issue: 5
Pages: 2704-13
Publication
First Author: Richer AL
Year: 2017
Journal: Cancer Res
Title: WEE1 Kinase Inhibitor AZD1775 Has Preclinical Efficacy in LKB1-Deficient Non-Small Cell Lung Cancer.
Volume: 77
Issue: 17
Pages: 4663-4672
Publication
First Author: Vadnais C
Year: 2012
Journal: Nucleic Acids Res
Title: CUX1 transcription factor is required for optimal ATM/ATR-mediated responses to DNA damage.
Volume: 40
Issue: 10
Pages: 4483-95
Publication
First Author: Liu X
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Overlapping functions between XLF repair protein and 53BP1 DNA damage response factor in end joining and lymphocyte development.
Volume: 109
Issue: 10
Pages: 3903-8
Publication  
First Author: Wang S
Year: 2022
Journal: J Mol Cell Cardiol
Title: Deletion of SIRT6 in vascular smooth muscle cells facilitates vascular calcification via suppression of DNA damage repair.
Volume: 173
Pages: 154-168
Publication
First Author: Sluss HK
Year: 2010
Journal: Mol Cancer Res
Title: Phosphorylation of p53 serine 18 upregulates apoptosis to suppress Myc-induced tumorigenesis.
Volume: 8
Issue: 2
Pages: 216-22
Publication
First Author: Carr MI
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Phosphorylation of the Mdm2 oncoprotein by the c-Abl tyrosine kinase regulates p53 tumor suppression and the radiosensitivity of mice.
Volume: 113
Issue: 52
Pages: 15024-15029
Publication
First Author: Kumar V
Year: 2017
Journal: Nucleic Acids Res
Title: Homeostatic nuclear RAGE-ATM interaction is essential for efficient DNA repair.
Volume: 45
Issue: 18
Pages: 10595-10613