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Search results 801 to 900 out of 1419 for Pdx1

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Type Details Score
Publication
25371201 | J:218260
First Author: Masjkur J
Year: 2014
Journal: J Biol Chem
Title: Hes3 is expressed in the adult pancreatic islet and regulates gene expression, cell growth, and insulin release.
Volume: 289
Issue: 51
Pages: 35503-16
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Publication
22983607 | J:194563
First Author: Shojima N
Year: 2012
Journal: Diabetologia
Title: Depletion of homeodomain-interacting protein kinase 3 impairs insulin secretion and glucose tolerance in mice.
Volume: 55
Issue: 12
Pages: 3318-30
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Publication
28919426 | J:254324
First Author: Jung H
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Improving glycemic control in model mice with type 2 diabetes by increasing superoxide dismutase (SOD) activity using silk fibroin hydrolysate (SFH).
Volume: 493
Issue: 1
Pages: 115-119
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Publication
22456697 | J:185166
First Author: Nakamura A
Year: 2012
Journal: Diabetologia
Title: Control of beta cell function and proliferation in mice stimulated by small-molecule glucokinase activator under various conditions.
Volume: 55
Issue: 6
Pages: 1745-54
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Publication
27653523 | J:238757
First Author: Wu RT
Year: 2017
Journal: Aging Cell
Title: Opposing impacts on healthspan and longevity by limiting dietary selenium in telomere dysfunctional mice.
Volume: 16
Issue: 1
Pages: 125-135
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Publication
30397183 | J:268920
First Author: Gupta D
Year: 2018
Journal: J Biol Chem
Title: β-Cell mass restoration by α7 nicotinic acetylcholine receptor activation.
Volume: 293
Issue: 52
Pages: 20295-20306
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Publication
18029451 | J:128497
First Author: Xie T
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Beta cell-specific deficiency of the stimulatory G protein alpha-subunit Gsalpha leads to reduced beta cell mass and insulin-deficient diabetes.
Volume: 104
Issue: 49
Pages: 19601-6
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Publication
23077629 | J:192209
First Author: Miyazaki S
Year: 2012
Journal: PLoS One
Title: Acinar-to-ductal metaplasia induced by adenovirus-mediated pancreatic expression of Isl1.
Volume: 7
Issue: 10
Pages: e47536
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Publication
15688412 | J:96794
First Author: Mathieu A
Year: 2005
Journal: Int J Cancer
Title: Transgenic expression of CCK2 receptors sensitizes murine pancreatic acinar cells to carcinogen-induced preneoplastic lesions formation.
Volume: 115
Issue: 1
Pages: 46-54
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Publication
24633305 | J:210314
First Author: Ardestani A
Year: 2014
Journal: Nat Med
Title: MST1 is a key regulator of beta cell apoptosis and dysfunction in diabetes.
Volume: 20
Issue: 4
Pages: 385-397
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Publication
37423392 | J:355449
 
First Author: Blandino-Rosano M
Year: 2023
Journal: Mol Metab
Title: Raptor levels are critical for β-cell adaptation to a high-fat diet in male mice.
Volume: 75
Pages: 101769
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Publication
18560803 | J:329194
First Author: Wang XD
Year: 2008
Journal: Diabetologia
Title: Molecular mechanisms for hyperinsulinaemia induced by overproduction of selenium-dependent glutathione peroxidase-1 in mice.
Volume: 51
Issue: 8
Pages: 1515-24
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Publication
23382448 | J:208553
First Author: Kanji MS
Year: 2013
Journal: Diabetes
Title: Dicer1 is required to repress neuronal fate during endocrine cell maturation.
Volume: 62
Issue: 5
Pages: 1602-11
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Publication
29605295 | J:270542
First Author: Matsuzawa T
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Heparan sulfate in pancreatic β-cells contributes to normal glucose homeostasis by regulating insulin secretion.
Volume: 499
Issue: 3
Pages: 688-695
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Publication
28790184 | J:244300
First Author: Benrick A
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Adiponectin protects against development of metabolic disturbances in a PCOS mouse model.
Volume: 114
Issue: 34
Pages: E7187-E7196
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Publication
37659738 | J:340591
 
First Author: Xing C
Year: 2023
Journal: Biochem Pharmacol
Title: Eicosapentaenoic acid metabolites promotes the trans-differentiation of pancreatic α cells to β cells.
Volume: 216
Pages: 115775
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Publication
25028525 | J:230123
First Author: Ediger BN
Year: 2014
Journal: Diabetes
Title: Islet-1 Is essential for pancreatic β-cell function.
Volume: 63
Issue: 12
Pages: 4206-17
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Publication
23274887 | J:208586
First Author: Valtat B
Year: 2013
Journal: Diabetes
Title: Fetal PGC-1α overexpression programs adult pancreatic β-cell dysfunction.
Volume: 62
Issue: 4
Pages: 1206-16
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Publication
28115692 | J:240879
First Author: Juliana CA
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: ATF5 regulates β-cell survival during stress.
Volume: 114
Issue: 6
Pages: 1341-1346
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Publication
37625131 | J:343219
First Author: Ueki K
Year: 2023
Journal: Diabetes
Title: Establishment of Pancreatic β-Cell-Specific Gene Knockout System Based on CRISPR-Cas9 Technology With AAV8-Mediated gRNA Delivery.
Volume: 72
Issue: 11
Pages: 1609-1620
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Publication
10768094 | J:61998
First Author: Yamaoka T
Year: 2000
Journal: Diabetologia
Title: Diabetes and pancreatic tumours in transgenic mice expressing Pa x 6.
Volume: 43
Issue: 3
Pages: 332-9
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Publication
18682608 | J:143133
First Author: Ishikawa M
Year: 2008
Journal: J Lipid Res
Title: Cholesterol accumulation and diabetes in pancreatic beta-cell-specific SREBP-2 transgenic mice: a new model for lipotoxicity.
Volume: 49
Issue: 12
Pages: 2524-34
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Publication
19812721 | J:153878
First Author: Du YC
Year: 2009
Journal: PLoS One
Title: Activation of PyMT in beta cells induces irreversible hyperplasia, but oncogene-dependent acinar cell carcinomas when activated in pancreatic progenitors.
Volume: 4
Issue: 9
Pages: e6932
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Publication
20547979 | J:169348
First Author: Gurevitch D
Year: 2010
Journal: Diabetes
Title: Elimination of negative feedback control mechanisms along the insulin signaling pathway improves beta-cell function under stress.
Volume: 59
Issue: 9
Pages: 2188-97
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Publication
21509441 | J:172806
First Author: Hakonen E
Year: 2011
Journal: Diabetologia
Title: Epidermal growth factor (EGF)-receptor signalling is needed for murine beta cell mass expansion in response to high-fat diet and pregnancy but not after pancreatic duct ligation.
Volume: 54
Issue: 7
Pages: 1735-43
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Publication
23339455 | J:196509
First Author: Campos ML
Year: 2013
Journal: Biochem J
Title: ICAT is a novel Ptf1a interactor that regulates pancreatic acinar differentiation and displays altered expression in tumours.
Volume: 451
Issue: 3
Pages: 395-405
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Publication
24816367 | J:214756
First Author: Nackiewicz D
Year: 2014
Journal: Diabetologia
Title: TLR2/6 and TLR4-activated macrophages contribute to islet inflammation and impair beta cell insulin gene expression via IL-1 and IL-6.
Volume: 57
Issue: 8
Pages: 1645-54
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Publication
24814049 | J:217033
First Author: Kurano M
Year: 2014
Journal: Biochim Biophys Acta
Title: Induction of insulin secretion by apolipoprotein M, a carrier for sphingosine 1-phosphate.
Volume: 1841
Issue: 9
Pages: 1217-26
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Publication
25147338 | J:227166
First Author: Cochran BJ
Year: 2014
Journal: Arterioscler Thromb Vasc Biol
Title: Apolipoprotein A-I increases insulin secretion and production from pancreatic β-cells via a G-protein-cAMP-PKA-FoxO1-dependent mechanism.
Volume: 34
Issue: 10
Pages: 2261-7
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Publication
29348175 | J:262598
First Author: Iwaoka R
Year: 2018
Journal: J Biol Chem
Title: Glucose regulates MafA transcription factor abundance and insulin gene expression by inhibiting AMP-activated protein kinase in pancreatic β-cells.
Volume: 293
Issue: 10
Pages: 3524-3534
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Publication
31765698 | J:284201
First Author: Nilsson O
Year: 2020
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Apolipoprotein A-I primes beta cells to increase glucose stimulated insulin secretion.
Volume: 1866
Issue: 3
Pages: 165613
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Publication
31142539 | J:295731
 
First Author: Helker CSM
Year: 2019
Journal: Development
Title: A whole organism small molecule screen identifies novel regulators of pancreatic endocrine development.
Volume: 146
Issue: 14
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Publication
34592314 | J:312782
First Author: Jetton TL
Year: 2021
Journal: J Biol Chem
Title: SetD7 (Set7/9) is a novel target of PPARγ that promotes the adaptive pancreatic β-cell glycemic response.
Volume: 297
Issue: 5
Pages: 101250
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Publication
21339733 | J:174642
First Author: Seux M
Year: 2011
Journal: Oncogene
Title: TP53INP1 decreases pancreatic cancer cell migration by regulating SPARC expression.
Volume: 30
Issue: 27
Pages: 3049-61
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Publication
26056141 | J:227321
First Author: Xie CM
Year: 2015
Journal: J Cell Biol
Title: Erbin is a novel substrate of the Sag-βTrCP E3 ligase that regulates KrasG12D-induced skin tumorigenesis.
Volume: 209
Issue: 5
Pages: 721-37
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Publication
30503750 | J:272592
First Author: Farack L
Year: 2019
Journal: Dev Cell
Title: Transcriptional Heterogeneity of Beta Cells in the Intact Pancreas.
Volume: 48
Issue: 1
Pages: 115-125.e4
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Publication
27984728 | J:238055
First Author: Grabocka E
Year: 2016
Journal: Cell
Title: Mutant KRAS Enhances Tumor Cell Fitness by Upregulating Stress Granules.
Volume: 167
Issue: 7
Pages: 1803-1813.e12
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Publication
32795414 | J:360185
First Author: Hoshino A
Year: 2020
Journal: Cell
Title: Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers.
Volume: 182
Issue: 4
Pages: 1044-1061.e18
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Publication
27265504 | J:232333
First Author: Steele CW
Year: 2016
Journal: Cancer Cell
Title: CXCR2 Inhibition Profoundly Suppresses Metastases and Augments Immunotherapy in Pancreatic Ductal Adenocarcinoma.
Volume: 29
Issue: 6
Pages: 832-845
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Publication
27454298 | J:237113
First Author: Lesina M
Year: 2016
Journal: J Clin Invest
Title: RelA regulates CXCL1/CXCR2-dependent oncogene-induced senescence in murine Kras-driven pancreatic carcinogenesis.
Volume: 126
Issue: 8
Pages: 2919-32
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Publication
36241718 | J:339253
First Author: Cheng R
Year: 2023
Journal: Cell Res
Title: A novel protein RASON encoded by a lncRNA controls oncogenic RAS signaling in KRAS mutant cancers.
Volume: 33
Issue: 1
Pages: 30-45
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Publication
14681207 | J:87196
First Author: Aguirre AJ
Year: 2003
Journal: Genes Dev
Title: Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma.
Volume: 17
Issue: 24
Pages: 3112-26
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Publication
14706336 | J:87973
First Author: Hingorani SR
Year: 2003
Journal: Cancer Cell
Title: Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse.
Volume: 4
Issue: 6
Pages: 437-50
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15894267 | J:98936
First Author: Hingorani SR
Year: 2005
Journal: Cancer Cell
Title: Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice.
Volume: 7
Issue: 5
Pages: 469-83
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Publication
25470546 | J:215816
First Author: Brouwers B
Year: 2014
Journal: Cell Metab
Title: Impaired islet function in commonly used transgenic mouse lines due to human growth hormone minigene expression.
Volume: 20
Issue: 6
Pages: 979-90
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Publication
25629724 | J:219792
 
First Author: Schlomann U
Year: 2015
Journal: Nat Commun
Title: ADAM8 as a drug target in pancreatic cancer.
Volume: 6
Pages: 6175
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Publication
22764048 | J:187631
First Author: Kredo-Russo S
Year: 2012
Journal: Development
Title: Pancreas-enriched miRNA refines endocrine cell differentiation.
Volume: 139
Issue: 16
Pages: 3021-31
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Publication
28235199 | J:240394
First Author: Welsch ME
Year: 2017
Journal: Cell
Title: Multivalent Small-Molecule Pan-RAS Inhibitors.
Volume: 168
Issue: 5
Pages: 878-889.e29
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Publication
26387541 | J:234311
First Author: Nitzki F
Year: 2016
Journal: Oncogene
Title: Hedgehog/Patched-associated rhabdomyosarcoma formation from delta1-expressing mesodermal cells.
Volume: 35
Issue: 22
Pages: 2923-31
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Publication
26411367 | J:234310
First Author: Kuo TL
Year: 2016
Journal: Oncogene
Title: APC haploinsufficiency coupled with p53 loss sufficiently induces mucinous cystic neoplasms and invasive pancreatic carcinoma in mice.
Volume: 35
Issue: 17
Pages: 2223-34
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Publication
27543868 | J:309224
First Author: Sugiyama Y
Year: 2016
Journal: Pol J Pathol
Title: Gli2 protein expression level is a feasible marker of ligand-dependent hedgehog activation in pancreatic neoplasms.
Volume: 67
Issue: 2
Pages: 136-44
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Publication
27628423 | J:242182
 
First Author: Aiello NM
Year: 2016
Journal: Nat Commun
Title: Metastatic progression is associated with dynamic changes in the local microenvironment.
Volume: 7
Pages: 12819
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Publication
34345207 | J:336894
First Author: Jia Y
Year: 2021
Journal: Int J Biol Sci
Title: Crosstalk between hypoxia-sensing ULK1/2 and YAP-driven glycolysis fuels pancreatic ductal adenocarcinoma development.
Volume: 17
Issue: 11
Pages: 2772-2794
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Publication
32586050 | J:305914
 
First Author: Hsieh MJ
Year: 2020
Journal: Int J Mol Sci
Title: Inactivation of APC Induces CD34 Upregulation to Promote Epithelial-Mesenchymal Transition and Cancer Stem Cell Traits in Pancreatic Cancer.
Volume: 21
Issue: 12
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Publication
27893715 | J:241235
First Author: Huang PH
Year: 2017
Journal: Oncogene
Title: TGFβ promotes mesenchymal phenotype of pancreatic cancer cells, in part, through epigenetic activation of VAV1.
Volume: 36
Issue: 16
Pages: 2202-2214
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Publication
21233348 | J:168148
First Author: Ting DT
Year: 2011
Journal: Science
Title: Aberrant overexpression of satellite repeats in pancreatic and other epithelial cancers.
Volume: 331
Issue: 6017
Pages: 593-6
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Publication
31109321 | J:349033
First Author: Weng CC
Year: 2019
Journal: Mol Cancer
Title: Loss of the transcriptional repressor TGIF1 results in enhanced Kras-driven development of pancreatic cancer.
Volume: 18
Issue: 1
Pages: 96
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Publication
32188706 | J:288813
First Author: Yuan S
Year: 2020
Journal: Cancer Discov
Title: Global Regulation of the Histone Mark H3K36me2 Underlies Epithelial Plasticity and Metastatic Progression.
Volume: 10
Issue: 6
Pages: 854-871
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Publication
31843590 | J:291952
First Author: Perusina Lanfranca M
Year: 2020
Journal: Gastroenterology
Title: Interleukin 22 Signaling Regulates Acinar Cell Plasticity to Promote Pancreatic Tumor Development in Mice.
Volume: 158
Issue: 5
Pages: 1417-1432.e11
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Publication
19878870 | J:153948
First Author: Gidekel Friedlander SY
Year: 2009
Journal: Cancer Cell
Title: Context-dependent transformation of adult pancreatic cells by oncogenic K-Ras.
Volume: 16
Issue: 5
Pages: 379-89
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25985394 | J:309322
First Author: Costa-Silva B
Year: 2015
Journal: Nat Cell Biol
Title: Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver.
Volume: 17
Issue: 6
Pages: 816-26
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Publication
30809277 | J:349142
First Author: Kuo TL
Year: 2019
Journal: Theranostics
Title: β-catenin-activated autocrine PDGF/Src signaling is a therapeutic target in pancreatic cancer.
Volume: 9
Issue: 2
Pages: 324-336
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Publication
20631070 | J:162233
First Author: Sasajima J
Year: 2010
Journal: Cancer Res
Title: Transplanting normal vascular proangiogenic cells to tumor-bearing mice triggers vascular remodeling and reduces hypoxia in tumors.
Volume: 70
Issue: 15
Pages: 6283-92
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Publication
25723399 | J:225361
First Author: Qu D
Year: 2015
Journal: PLoS One
Title: Doublecortin-like kinase 1 is elevated serologically in pancreatic ductal adenocarcinoma and widely expressed on circulating tumor cells.
Volume: 10
Issue: 2
Pages: e0118933
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Publication
32609742 | J:294732
First Author: Sato K
Year: 2020
Journal: PLoS One
Title: Hyperglycemia enhances pancreatic cancer progression accompanied by elevations in phosphorylated STAT3 and MYC levels.
Volume: 15
Issue: 7
Pages: e0235573
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Publication
28671190 | J:249537
 
First Author: Biancur DE
Year: 2017
Journal: Nat Commun
Title: Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism.
Volume: 8
Pages: 15965
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Publication
29920274 | J:263586
First Author: Aiello NM
Year: 2018
Journal: Dev Cell
Title: EMT Subtype Influences Epithelial Plasticity and Mode of Cell Migration.
Volume: 45
Issue: 6
Pages: 681-695.e4
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Publication
22186407 | J:181720
First Author: Kim HJ
Year: 2012
Journal: Endocrinology
Title: Overexpression of FoxO1 in the hypothalamus and pancreas causes obesity and glucose intolerance.
Volume: 153
Issue: 2
Pages: 659-71
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Publication
32917658 | J:360085
First Author: Yang X
Year: 2020
Journal: Cancer Immunol Res
Title: Lactate-Modulated Immunosuppression of Myeloid-Derived Suppressor Cells Contributes to the Radioresistance of Pancreatic Cancer.
Volume: 8
Issue: 11
Pages: 1440-1451
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Publication
19033400 | J:146940
First Author: Puri S
Year: 2009
Journal: Diabetes
Title: A role for von Hippel-Lindau protein in pancreatic beta-cell function.
Volume: 58
Issue: 2
Pages: 433-41
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Publication
16169491 | J:101522
First Author: Dessimoz J
Year: 2005
Journal: Curr Biol
Title: Pancreas-specific deletion of beta-catenin reveals Wnt-dependent and Wnt-independent functions during development.
Volume: 15
Issue: 18
Pages: 1677-83
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Publication
12459030 | J:105821
First Author: Kos M
Year: 2002
Journal: J Mol Endocrinol
Title: Down but not out? A novel protein isoform of the estrogen receptor alpha is expressed in the estrogen receptor alpha knockout mouse.
Volume: 29
Issue: 3
Pages: 281-6
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Publication
19901970 | J:157020
First Author: Xu X
Year: 2010
Journal: Oncogene
Title: Synergistic action of Smad4 and Pten in suppressing pancreatic ductal adenocarcinoma formation in mice.
Volume: 29
Issue: 5
Pages: 674-86
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Publication
26187948 | J:226073
First Author: Jiang FX
Year: 2015
Journal: Biol Open
Title: Transcriptome of pancreas-specific Bmpr1a-deleted islets links to TPH1-5-HT axis.
Volume: 4
Issue: 8
Pages: 1016-23
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Publication
17393136 | J:141585
First Author: Cantley J
Year: 2007
Journal: Diabetologia
Title: Pancreatic deletion of insulin receptor substrate 2 reduces beta and alpha cell mass and impairs glucose homeostasis in mice.
Volume: 50
Issue: 6
Pages: 1248-56
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Publication
17599554 | J:127051
First Author: Lee JY
Year: 2007
Journal: Biochim Biophys Acta
Title: The transcription factors Stat5a/b are not required for islet development but modulate pancreatic beta-cell physiology upon aging.
Volume: 1773
Issue: 9
Pages: 1455-61
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Publication
22338079 | J:186864
First Author: Hardy AB
Year: 2012
Journal: Am J Physiol Endocrinol Metab
Title: Effects of high-fat diet feeding on Znt8-null mice: differences between β-cell and global knockout of Znt8.
Volume: 302
Issue: 9
Pages: E1084-96
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Publication
32581043 | J:349148
 
First Author: Choueiry F
Year: 2020
Journal: J Immunother Cancer
Title: CD200 promotes immunosuppression in the pancreatic tumor microenvironment.
Volume: 8
Issue: 1
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Publication
27797936 | J:349054
First Author: Mace TA
Year: 2018
Journal: Gut
Title: IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer.
Volume: 67
Issue: 2
Pages: 320-332
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Publication
30504844 | J:268859
First Author: Pinho AV
Year: 2018
Journal: Nat Commun
Title: ROBO2 is a stroma suppressor gene in the pancreas and acts via TGF-β signalling.
Volume: 9
Issue: 1
Pages: 5083
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Publication
19808021 | J:153661
First Author: Fu A
Year: 2009
Journal: Cell Metab
Title: Loss of Lkb1 in adult beta cells increases beta cell mass and enhances glucose tolerance in mice.
Volume: 10
Issue: 4
Pages: 285-95
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Publication
26977883 | J:231763
First Author: Wei D
Year: 2016
Journal: Cancer Cell
Title: KLF4 Is Essential for Induction of Cellular Identity Change and Acinar-to-Ductal Reprogramming during Early Pancreatic Carcinogenesis.
Volume: 29
Issue: 3
Pages: 324-38
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Publication
31915377 | J:290070
First Author: Su J
Year: 2020
Journal: Nature
Title: TGF-β orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1.
Volume: 577
Issue: 7791
Pages: 566-571
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Publication
21586612 | J:174088
First Author: Corcoran RB
Year: 2011
Journal: Cancer Res
Title: STAT3 plays a critical role in KRAS-induced pancreatic tumorigenesis.
Volume: 71
Issue: 14
Pages: 5020-9
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Publication
16642022 | J:109011
First Author: Ueki K
Year: 2006
Journal: Nat Genet
Title: Total insulin and IGF-I resistance in pancreatic beta cells causes overt diabetes.
Volume: 38
Issue: 5
Pages: 583-8
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Publication
30620636 | J:274021
First Author: Bethea M
Year: 2019
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