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Search results 901 to 1000 out of 1419 for Pdx1

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Type Details Score
Publication
30590101 | J:270061
 
First Author: Kibe S
Year: 2019
Journal: Cancer Lett
Title: Cancer-associated acinar-to-ductal metaplasia within the invasive front of pancreatic cancer contributes to local invasion.
Volume: 444
Pages: 70-81
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Publication
27758884 | J:238010
First Author: Driscoll DR
Year: 2016
Journal: Cancer Res
Title: mTORC2 Signaling Drives the Development and Progression of Pancreatic Cancer.
Volume: 76
Issue: 23
Pages: 6911-6923
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Publication
24395249 | J:205582
First Author: Saborowski M
Year: 2014
Journal: Genes Dev
Title: A modular and flexible ESC-based mouse model of pancreatic cancer.
Volume: 28
Issue: 1
Pages: 85-97
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Publication
17909062 | J:125575
First Author: Clark CE
Year: 2007
Journal: Cancer Res
Title: Dynamics of the immune reaction to pancreatic cancer from inception to invasion.
Volume: 67
Issue: 19
Pages: 9518-27
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Publication
21952247 | J:179100
First Author: Plank JL
Year: 2011
Journal: Endocrinology
Title: Loss of Foxd3 results in decreased β-cell proliferation and glucose intolerance during pregnancy.
Volume: 152
Issue: 12
Pages: 4589-600
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Publication
29606348 | J:260702
First Author: Li L
Year: 2018
Journal: Cancer Cell
Title: GKAP Acts as a Genetic Modulator of NMDAR Signaling to Govern Invasive Tumor Growth.
Volume: 33
Issue: 4
Pages: 736-751.e5
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Publication
24902898 | J:229998
First Author: Grasso D
Year: 2014
Journal: Cell Death Differ
Title: Genetic inactivation of the pancreatitis-inducible gene Nupr1 impairs PanIN formation by modulating Kras(G12D)-induced senescence.
Volume: 21
Issue: 10
Pages: 1633-41
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Publication
25584895 | J:219808
First Author: Wong PP
Year: 2015
Journal: Cancer Cell
Title: Dual-action combination therapy enhances angiogenesis while reducing tumor growth and spread.
Volume: 27
Issue: 1
Pages: 123-37
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Publication
24607504 | J:232076
First Author: Keenan BP
Year: 2014
Journal: Gastroenterology
Title: A Listeria vaccine and depletion of T-regulatory cells activate immunity against early stage pancreatic intraepithelial neoplasms and prolong survival of mice.
Volume: 146
Issue: 7
Pages: 1784-94.e6
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Publication
28386018 | J:242294
First Author: Sinha S
Year: 2017
Journal: Cancer Res
Title: PanIN Neuroendocrine Cells Promote Tumorigenesis via Neuronal Cross-talk.
Volume: 77
Issue: 8
Pages: 1868-1879
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Publication
23840665 | J:203716
First Author: Courtin A
Year: 2013
Journal: PLoS One
Title: Anti-tumour efficacy of capecitabine in a genetically engineered mouse model of pancreatic cancer.
Volume: 8
Issue: 6
Pages: e67330
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Publication
23407165 | J:195770
First Author: Guillaumond F
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma.
Volume: 110
Issue: 10
Pages: 3919-24
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Publication
28254412 | J:240391
 
First Author: Leal AS
Year: 2017
Journal: Cancer Lett
Title: Bromodomain inhibitors, JQ1 and I-BET 762, as potential therapies for pancreatic cancer.
Volume: 394
Pages: 76-87
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Publication
27300433 | J:232330
First Author: DuFort CC
Year: 2016
Journal: Cancer Cell
Title: Tension and Transformation in Pancreas Cancer: Can Phenotype Break Free from the Chrysalis of Genotype?
Volume: 29
Issue: 6
Pages: 780-782
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Publication
37190324 | J:335631
 
First Author: Yang D
Year: 2023
Journal: Cancers (Basel)
Title: Cross-Dataset Single-Cell Analysis Identifies Temporal Alterations in Cell Populations of Primary Pancreatic Tumor and Liver Metastasis.
Volume: 15
Issue: 8
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Publication
30930235 | J:274212
 
First Author: Fabian A
Year: 2019
Journal: Cancer Lett
Title: Metastasis of pancreatic cancer: An uninflamed liver micromilieu controls cell growth and cancer stem cell properties by oxidative phosphorylation in pancreatic ductal epithelial cells.
Volume: 453
Pages: 95-106
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Publication
25675507 | J:220173
First Author: Guillaumond F
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma.
Volume: 112
Issue: 8
Pages: 2473-8
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Publication
28315323 | J:325940
First Author: Jiang SH
Year: 2017
Journal: Gastroenterology
Title: Increased Serotonin Signaling Contributes to the Warburg Effect in Pancreatic Tumor Cells Under Metabolic Stress and Promotes Growth of Pancreatic Tumors in Mice.
Volume: 153
Issue: 1
Pages: 277-291.e19
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Publication
28408354 | J:242491
 
First Author: Chen X
Year: 2017
Journal: Cancer Lett
Title: Therapeutic effects of Argyrin F in pancreatic adenocarcinoma.
Volume: 399
Pages: 20-28
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Publication
28765154 | J:249042
First Author: D'Costa Z
Year: 2017
Journal: Cancer Res
Title: Gemcitabine-Induced TIMP1 Attenuates Therapy Response and Promotes Tumor Growth and Liver Metastasis in Pancreatic Cancer.
Volume: 77
Issue: 21
Pages: 5952-5962
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Publication
21984975 | J:185636
First Author: Ying H
Year: 2011
Journal: Cancer Discov
Title: PTEN is a major tumor suppressor in pancreatic ductal adenocarcinoma and regulates an NF-κB-cytokine network.
Volume: 1
Issue: 2
Pages: 158-69
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Publication
29621546 | J:271449
First Author: Cao XY
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Aberrant upregulation of KLK10 promotes metastasis via enhancement of EMT and FAK/SRC/ERK axis in PDAC.
Volume: 499
Issue: 3
Pages: 584-593
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Publication
35752173 | J:354665
First Author: He D
Year: 2022
Journal: Mol Cell
Title: Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis.
Volume: 82
Issue: 16
Pages: 3045-3060.e11
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Publication
27829137 | J:251957
First Author: Flint TR
Year: 2016
Journal: Cell Metab
Title: Tumor-Induced IL-6 Reprograms Host Metabolism to Suppress Anti-tumor Immunity.
Volume: 24
Issue: 5
Pages: 672-684
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Publication
26172047 | J:238533
First Author: Greco SH
Year: 2015
Journal: PLoS One
Title: TGF-β Blockade Reduces Mortality and Metabolic Changes in a Validated Murine Model of Pancreatic Cancer Cachexia.
Volume: 10
Issue: 7
Pages: e0132786
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Publication
25368022 | J:218262
First Author: Sainz B Jr
Year: 2014
Journal: Cancer Res
Title: ISG15 is a critical microenvironmental factor for pancreatic cancer stem cells.
Volume: 74
Issue: 24
Pages: 7309-20
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Publication
19460966 | J:149213
First Author: Olive KP
Year: 2009
Journal: Science
Title: Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer.
Volume: 324
Issue: 5933
Pages: 1457-61
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Publication
30451898 | J:269952
First Author: Santofimia-Castaño P
Year: 2018
Journal: Sci Rep
Title: Inactivation of NUPR1 promotes cell death by coupling ER-stress responses with necrosis.
Volume: 8
Issue: 1
Pages: 16999
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Publication
21403843 | J:171634
First Author: Fendrich V
Year: 2011
Journal: Neoplasia
Title: Detection of precursor lesions of pancreatic adenocarcinoma in PET-CT in a genetically engineered mouse model of pancreatic cancer.
Volume: 13
Issue: 2
Pages: 180-6
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Publication
36919330 | J:335589
First Author: He F
Year: 2023
Journal: Cancer Res
Title: FPR2 Shapes an Immune-Excluded Pancreatic Tumor Microenvironment and Drives T-cell Exhaustion in a Sex-Dependent Manner.
Volume: 83
Issue: 10
Pages: 1628-1645
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Publication
32156729 | J:286585
First Author: Wasylishen AR
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Men1 maintains exocrine pancreas homeostasis in response to inflammation and oncogenic stress.
Volume: 117
Issue: 12
Pages: 6622-6629
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Publication
21242978 | J:173715
First Author: Shields DJ
Year: 2011
Journal: Oncogene
Title: Oncogenic Ras/Src cooperativity in pancreatic neoplasia.
Volume: 30
Issue: 18
Pages: 2123-34
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26144316 | J:224529
First Author: Palm W
Year: 2015
Journal: Cell
Title: The Utilization of Extracellular Proteins as Nutrients Is Suppressed by mTORC1.
Volume: 162
Issue: 2
Pages: 259-270
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Publication
28757253 | J:252097
First Author: Roe JS
Year: 2017
Journal: Cell
Title: Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis.
Volume: 170
Issue: 5
Pages: 875-888.e20
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Publication
23980075 | J:316965
First Author: Lashinger LM
Year: 2013
Journal: Cancer Prev Res (Phila)
Title: Dietary energy balance modulation of Kras- and Ink4a/Arf+/--driven pancreatic cancer: the role of insulin-like growth factor-I.
Volume: 6
Issue: 10
Pages: 1046-55
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Publication
35561453 | J:325347
 
First Author: Jiang SH
Year: 2022
Journal: EBioMedicine
Title: Modeling of cancer-related body-wide effects identifies LTB4 as a diagnostic biomarker for pancreatic cancer.
Volume: 80
Pages: 104050
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Publication
19118015 | J:143028
First Author: Menon R
Year: 2009
Journal: Cancer Res
Title: Identification of novel alternative splice isoforms of circulating proteins in a mouse model of human pancreatic cancer.
Volume: 69
Issue: 1
Pages: 300-9
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28453537 | J:245950
First Author: Kersemans V
Year: 2017
Journal: PLoS One
Title: An efficient and robust MRI-guided radiotherapy planning approach for targeting abdominal organs and tumours in the mouse.
Volume: 12
Issue: 4
Pages: e0176693
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29135982 | J:252226
First Author: Baird JR
Year: 2017
Journal: PLoS One
Title: STING expression and response to treatment with STING ligands in premalignant and malignant disease.
Volume: 12
Issue: 11
Pages: e0187532
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Publication
31330317 | J:293294
First Author: Gao C
Year: 2019
Journal: Cell Mol Gastroenterol Hepatol
Title: PYK2 Is Involved in Premalignant Acinar Cell Reprogramming and Pancreatic Ductal Adenocarcinoma Maintenance by Phosphorylating β-CateninY654.
Volume: 8
Issue: 4
Pages: 561-578
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Publication
31413817 | J:317025
First Author: Strand MS
Year: 2019
Journal: Oncotarget
Title: Precision delivery of RAS-inhibiting siRNA to KRAS driven cancer via peptide-based nanoparticles.
Volume: 10
Issue: 46
Pages: 4761-4775
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Publication
35235808 | J:325480
First Author: Shields MA
Year: 2022
Journal: Cell Rep
Title: Gα13 loss in Kras/Tp53 mouse model of pancreatic tumorigenesis promotes tumors susceptible to rapamycin.
Volume: 38
Issue: 9
Pages: 110441
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Publication
23963802 | J:303013
First Author: Husain K
Year: 2013
Journal: Cancer Prev Res (Phila)
Title: Vitamin E δ-tocotrienol prolongs survival in the LSL-KrasG12D/+;LSL-Trp53R172H/+;Pdx-1-Cre (KPC) transgenic mouse model of pancreatic cancer.
Volume: 6
Issue: 10
Pages: 1074-83
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Publication
27489361 | J:236853
First Author: Grünwald B
Year: 2016
Journal: Mol Cancer Res
Title: Systemic Ablation of MMP-9 Triggers Invasive Growth and Metastasis of Pancreatic Cancer via Deregulation of IL6 Expression in the Bone Marrow.
Volume: 14
Issue: 11
Pages: 1147-1158
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Publication
26404002 | J:226774
First Author: Loncle C
Year: 2015
Journal: Cancer Res
Title: IL17 Functions through the Novel REG3β-JAK2-STAT3 Inflammatory Pathway to Promote the Transition from Chronic Pancreatitis to Pancreatic Cancer.
Volume: 75
Issue: 22
Pages: 4852-62
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24336331 | J:218641
First Author: Kühnemuth B
Year: 2015
Journal: Oncogene
Title: CUX1 modulates polarization of tumor-associated macrophages by antagonizing NF-κB signaling.
Volume: 34
Issue: 2
Pages: 177-87
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Publication
30863319 | J:309716
 
First Author: Li C
Year: 2019
Journal: Front Physiol
Title: MSP-RON Signaling Is Activated in the Transition From Pancreatic Intraepithelial Neoplasia (PanIN) to Pancreatic Ductal Adenocarcinoma (PDAC).
Volume: 10
Pages: 147
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Publication
38902362 | J:352006
First Author: Jacobson R
Year: 2024
Journal: Sci Rep
Title: Differential extracellular vesicle concentration and their biomarker expression of integrin α(v)/β(5), EpCAM, and glypican-1 in pancreatic cancer models.
Volume: 14
Issue: 1
Pages: 14273
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Publication
27267807 | J:232848
First Author: Gore J
Year: 2016
Journal: Cancer Lett
Title: Combined targeting of TGF-β, EGFR and HER2 suppresses lymphangiogenesis and metastasis in a pancreatic cancer model.
Volume: 379
Issue: 1
Pages: 143-53
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17785207 | J:124969
First Author: Siveke JT
Year: 2007
Journal: Cancer Cell
Title: Concomitant pancreatic activation of Kras(G12D) and Tgfa results in cystic papillary neoplasms reminiscent of human IPMN.
Volume: 12
Issue: 3
Pages: 266-79
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37255660 | J:347476
First Author: Kaune T
Year: 2023
Journal: iScience
Title: Gender-specific changes of the gut microbiome correlate with tumor development in murine models of pancreatic cancer.
Volume: 26
Issue: 6
Pages: 106841
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29050937 | J:253991
First Author: Jiang S
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Integrated expression profiling of potassium channels identifys KCNN4 as a prognostic biomarker of pancreatic cancer.
Volume: 494
Issue: 1-2
Pages: 113-119
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23887057 | J:202529
First Author: Shen R
Year: 2013
Journal: Cancer Lett
Title: The biological features of PanIN initiated from oncogenic Kras mutation in genetically engineered mouse models.
Volume: 339
Issue: 1
Pages: 135-43
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23578383 | J:198521
First Author: Al Saati T
Year: 2013
Journal: Am J Pathol
Title: Oxidative stress induced by inactivation of TP53INP1 cooperates with KrasG12D to initiate and promote pancreatic carcinogenesis in the murine pancreas.
Volume: 182
Issue: 6
Pages: 1996-2004
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23689354 | J:200524
First Author: Li H
Year: 2013
Journal: Carcinogenesis
Title: Sulindac inhibits pancreatic carcinogenesis in LSL-KrasG12D-LSL-Trp53R172H-Pdx-1-Cre mice via suppressing aldo-keto reductase family 1B10 (AKR1B10).
Volume: 34
Issue: 9
Pages: 2090-8
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29414775 | J:262781
First Author: Maity G
Year: 2018
Journal: J Biol Chem
Title: The MAZ transcription factor is a downstream target of the oncoprotein Cyr61/CCN1 and promotes pancreatic cancer cell invasion via CRAF-ERK signaling.
Volume: 293
Issue: 12
Pages: 4334-4349
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29567829 | J:260710
First Author: Pushalkar S
Year: 2018
Journal: Cancer Discov
Title: The Pancreatic Cancer Microbiome Promotes Oncogenesis by Induction of Innate and Adaptive Immune Suppression.
Volume: 8
Issue: 4
Pages: 403-416
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19477428 | J:149663
First Author: Singh A
Year: 2009
Journal: Cancer Cell
Title: A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival.
Volume: 15
Issue: 6
Pages: 489-500
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34922945 | J:322176
First Author: Costamagna A
Year: 2022
Journal: Gastroenterology
Title: Docking Protein p130Cas Regulates Acinar to Ductal Metaplasia During Pancreatic Adenocarcinoma Development and Pancreatitis.
Volume: 162
Issue: 4
Pages: 1242-1255.e11
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21673986 | J:174139
First Author: Wang Z
Year: 2011
Journal: PLoS One
Title: Activated K-ras and INK4a/Arf deficiency cooperate during the development of pancreatic cancer by activation of Notch and NF-κB signaling pathways.
Volume: 6
Issue: 6
Pages: e20537
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33110235 | J:301792
First Author: Nimmakayala RK
Year: 2021
Journal: Oncogene
Title: Metabolic programming of distinct cancer stem cells promotes metastasis of pancreatic ductal adenocarcinoma.
Volume: 40
Issue: 1
Pages: 215-231
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26310823 | J:224975
 
First Author: Schneider P
Year: 2015
Journal: Nat Commun
Title: Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1.
Volume: 6
Pages: 8023
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27061193 | J:241175
First Author: Carapuça EF
Year: 2016
Journal: J Pathol
Title: Anti-stromal treatment together with chemotherapy targets multiple signalling pathways in pancreatic adenocarcinoma.
Volume: 239
Issue: 3
Pages: 286-96
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32580961 | J:296304
First Author: Wang F
Year: 2020
Journal: Cancer Res
Title: p38γ MAPK Is Essential for Aerobic Glycolysis and Pancreatic Tumorigenesis.
Volume: 80
Issue: 16
Pages: 3251-3264
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19629168 | J:151781
First Author: Vincent DF
Year: 2009
Journal: PLoS Genet
Title: Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas.
Volume: 5
Issue: 7
Pages: e1000575
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Publication
29222037 | J:253809
 
First Author: Rahn S
Year: 2018
Journal: Cancer Lett
Title: Diabetes as risk factor for pancreatic cancer: Hyperglycemia promotes epithelial-mesenchymal-transition and stem cell properties in pancreatic ductal epithelial cells.
Volume: 415
Pages: 129-150
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22351932 | J:182504
First Author: Cook N
Year: 2012
Journal: J Exp Med
Title: Gamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma.
Volume: 209
Issue: 3
Pages: 437-44
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35626052 | J:349029
 
First Author: Natarajan V
Year: 2022
Journal: Cancers (Basel)
Title: Acquired αSMA Expression in Pericytes Coincides with Aberrant Vascular Structure and Function in Pancreatic Ductal Adenocarcinoma.
Volume: 14
Issue: 10
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31815046 | J:349040
First Author: Yang J
Year: 2019
Journal: Am J Cancer Res
Title: Dendritic cell immunotherapy induces anti-tumor effect in a transgenic mouse model of pancreatic ductal adenocarcinoma.
Volume: 9
Issue: 11
Pages: 2456-2468
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35219699 | J:349104
First Author: Ganguly K
Year: 2022
Journal: Gastroenterology
Title: Mucin 5AC-Mediated CD44/ITGB1 Clustering Mobilizes Adipose-Derived Mesenchymal Stem Cells to Modulate Pancreatic Cancer Stromal Heterogeneity.
Volume: 162
Issue: 7
Pages: 2032-2046.e12
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31369062 | J:290838
First Author: Mendez R
Year: 2020
Journal: Carcinogenesis
Title: Microbial dysbiosis and polyamine metabolism as predictive markers for early detection of pancreatic cancer.
Volume: 41
Issue: 5
Pages: 561-570
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Publication
27248578 | J:349079
 
First Author: Lee JW
Year: 2016
Journal: Curr Protoc Pharmacol
Title: Genetically Engineered Mouse Models of Pancreatic Cancer: The KPC Model (LSL-Kras(G12D/+) ;LSL-Trp53(R172H/+) ;Pdx-1-Cre), Its Variants, and Their Application in Immuno-oncology Drug Discovery.
Volume: 73
Pages: 14.39.1-14.39.20
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32251410 | J:349151
First Author: Ferguson FM
Year: 2020
Journal: Nat Chem Biol
Title: Discovery of a selective inhibitor of doublecortin like kinase 1.
Volume: 16
Issue: 6
Pages: 635-643
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31433988 | J:299226
First Author: Burrack AL
Year: 2019
Journal: Cell Rep
Title: Combination PD-1 and PD-L1 Blockade Promotes Durable Neoantigen-Specific T Cell-Mediated Immunity in Pancreatic Ductal Adenocarcinoma.
Volume: 28
Issue: 8
Pages: 2140-2155.e6
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29367759 | J:261029
First Author: Fendrich V
Year: 2018
Journal: Oncogene
Title: Genetic and pharmacologic abrogation of Snail1 inhibits acinar-to-ductal metaplasia in precursor lesions of pancreatic ductal adenocarcinoma and pancreatic injury.
Volume: 37
Issue: 14
Pages: 1845-1856
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27919787 | J:239396
 
First Author: Garg B
Year: 2017
Journal: Cancer Lett
Title: Modulation of post-translational modifications in β-catenin and LRP6 inhibits Wnt signaling pathway in pancreatic cancer.
Volume: 388
Pages: 64-72
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30086262 | J:311766
First Author: Chugh S
Year: 2018
Journal: Gastroenterology
Title: Disruption of C1galt1 Gene Promotes Development and Metastasis of Pancreatic Adenocarcinomas in Mice.
Volume: 155
Issue: 5
Pages: 1608-1624
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Publication
32606001 | J:296622
First Author: Morita T
Year: 2020
Journal: Cancer Res
Title: CXCR4 in Tumor Epithelial Cells Mediates Desmoplastic Reaction in Pancreatic Ductal Adenocarcinoma.
Volume: 80
Issue: 19
Pages: 4058-4070
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28024083 | J:254380
First Author: Davidson SM
Year: 2017
Journal: Nat Med
Title: Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors.
Volume: 23
Issue: 2
Pages: 235-241
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Publication
27624879 | J:254486
 
First Author: Verma RK
Year: 2016
Journal: Sci Rep
Title: α-Mangostin-encapsulated PLGA nanoparticles inhibit pancreatic carcinogenesis by targeting cancer stem cells in human, and transgenic (Kras(G12D), and Kras(G12D)/tp53R270H) mice.
Volume: 6
Pages: 32743
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Publication
18547137 | J:139894
First Author: Faca VM
Year: 2008
Journal: PLoS Med
Title: A mouse to human search for plasma proteome changes associated with pancreatic tumor development.
Volume: 5
Issue: 6
Pages: e123
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30008881 | J:299376
First Author: Noguchi K
Year: 2018
Journal: Oncol Lett
Title: c-Met affects gemcitabine resistance during carcinogenesis in a mouse model of pancreatic cancer.
Volume: 16
Issue: 2
Pages: 1892-1898
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Publication
25557080 | J:219289
First Author: Boj SF
Year: 2015
Journal: Cell
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