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Search results 1 to 100 out of 154 for Acvrl1

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Category: Publication
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Type Details Score
Publication
12050147 | J:77840
First Author: Roman BL
Year: 2002
Journal: Development
Title: Disruption of acvrl1 increases endothelial cell number in zebrafish cranial vessels.
Volume: 129
Issue: 12
Pages: 3009-19
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Publication
24896812 | J:218508
First Author: Tual-Chalot S
Year: 2014
Journal: PLoS One
Title: Endothelial depletion of Acvrl1 in mice leads to arteriovenous malformations associated with reduced endoglin expression.
Volume: 9
Issue: 6
Pages: e98646
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Publication
12588795 | J:82115
First Author: Srinivasan S
Year: 2003
Journal: Hum Mol Genet
Title: A mouse model for hereditary hemorrhagic telangiectasia (HHT) type 2.
Volume: 12
Issue: 5
Pages: 473-82
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Publication
35440116 | J:324118
First Author: Wang G
Year: 2022
Journal: Nat Commun
Title: Endothelial progenitor cells stimulate neonatal lung angiogenesis through FOXF1-mediated activation of BMP9/ACVRL1 signaling.
Volume: 13
Issue: 1
Pages: 2080
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Publication
29253505 | J:257914
First Author: Lempereur A
Year: 2018
Journal: Dev Biol
Title: The TGFβ pathway is a key player for the endothelial-to-hematopoietic transition in the embryonic aorta.
Volume: 434
Issue: 2
Pages: 292-303
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Publication
22233626 | J:225017
 
First Author: Benzinou M
Year: 2012
Journal: Nat Commun
Title: Mouse and human strategies identify PTPN14 as a modifier of angiogenesis and hereditary haemorrhagic telangiectasia.
Volume: 3
Pages: 616
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Publication
26821948 | J:246772
First Author: Gkatzis K
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Interaction Between ALK1 Signaling and Connexin40 in the Development of Arteriovenous Malformations.
Volume: 36
Issue: 4
Pages: 707-17
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Publication
30571259 | J:287805
First Author: Thalgott JH
Year: 2018
Journal: Circulation
Title: Decreased Expression of Vascular Endothelial Growth Factor Receptor 1 Contributes to the Pathogenesis of Hereditary Hemorrhagic Telangiectasia Type 2.
Volume: 138
Issue: 23
Pages: 2698-2712
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Publication
19015642 | J:142792
First Author: Mahmoud M
Year: 2009
Journal: Lab Invest
Title: Endoglin and activin receptor-like-kinase 1 are co-expressed in the distal vessels of the lung: implications for two familial vascular dysplasias, HHT and PAH.
Volume: 89
Issue: 1
Pages: 15-25
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Publication
11062473 | J:65521
First Author: Urness LD
Year: 2000
Journal: Nat Genet
Title: Arteriovenous malformations in mice lacking activin receptor-like kinase-1.
Volume: 26
Issue: 3
Pages: 328-31
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Publication
31311865 | J:278336
First Author: Wang W
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: The TGFβ type I receptor TGFβRI functions as an inhibitor of BMP signaling in cartilage.
Volume: 116
Issue: 31
Pages: 15570-15579
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Publication
7488127 | J:29643
First Author: Wu X
Year: 1995
Journal: Biochem Biophys Res Commun
Title: Cloning and characterization of the murine activin receptor like kinase-1 (ALK-1) homolog.
Volume: 216
Issue: 1
Pages: 78-83
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Publication
19805914 | J:154620
First Author: Park SO
Year: 2009
Journal: J Clin Invest
Title: Real-time imaging of de novo arteriovenous malformation in a mouse model of hereditary hemorrhagic telangiectasia.
Volume: 119
Issue: 11
Pages: 3487-96
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Publication
12668602 | J:88467
 
First Author: Marchuk DA
Year: 2003
Journal: Hum Mol Genet
Title: Vascular morphogenesis: tales of two syndromes.
Volume: 12 Spec No 1
Pages: R97-112
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Publication
26398936 | J:226550
First Author: González-Núñez M
Year: 2015
Journal: Dis Model Mech
Title: Heterozygous disruption of activin receptor-like kinase 1 is associated with increased arterial pressure in mice.
Volume: 8
Issue: 11
Pages: 1427-39
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Publication
23945497 | J:301672
First Author: Muñoz-Félix JM
Year: 2014
Journal: Kidney Int
Title: Heterozygous disruption of activin receptor-like kinase 1 is associated with increased renal fibrosis in a mouse model of obstructive nephropathy.
Volume: 85
Issue: 2
Pages: 319-32
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Publication
35770075 | J:338278
 
First Author: Martínez-Salgado C
Year: 2022
Journal: Front Pharmacol
Title: Endothelial Activin Receptor-Like Kinase 1 (ALK1) Regulates Myofibroblast Emergence and Peritubular Capillary Stability in the Early Stages of Kidney Fibrosis.
Volume: 13
Pages: 843732
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Publication
18835925 | J:143303
First Author: Hao Q
Year: 2008
Journal: Am J Physiol Heart Circ Physiol
Title: Increased tissue perfusion promotes capillary dysplasia in the ALK1-deficient mouse brain following VEGF stimulation.
Volume: 295
Issue: 6
Pages: H2250-6
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Publication
21859819 | J:191704
First Author: Jerkic M
Year: 2011
Journal: Cardiovasc Res
Title: Pulmonary hypertension in adult Alk1 heterozygous mice due to oxidative stress.
Volume: 92
Issue: 3
Pages: 375-84
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Publication
20065063 | J:156543
First Author: Cunha SI
Year: 2010
Journal: J Exp Med
Title: Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis.
Volume: 207
Issue: 1
Pages: 85-100
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Publication
31689244 | J:296922
First Author: Ruiz S
Year: 2020
Journal: J Clin Invest
Title: Correcting Smad1/5/8, mTOR, and VEGFR2 treats pathology in hereditary hemorrhagic telangiectasia models.
Volume: 130
Issue: 2
Pages: 942-957
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Publication
28213819 | J:260038
First Author: Morine KJ
Year: 2017
Journal: Heart Vessels
Title: Conditional knockout of activin like kinase-1 (ALK-1) leads to heart failure without maladaptive remodeling.
Volume: 32
Issue: 5
Pages: 628-636
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Publication
19506300 | J:152268
First Author: Shao ES
Year: 2009
Journal: Blood
Title: Expression of vascular endothelial growth factor is coordinately regulated by the activin-like kinase receptors 1 and 5 in endothelial cells.
Volume: 114
Issue: 10
Pages: 2197-206
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Publication
28820968 | J:287906
 
First Author: Morine KJ
Year: 2017
Journal: Cardiovasc Pathol
Title: Reduced activin receptor-like kinase 1 activity promotes cardiac fibrosis in heart failure.
Volume: 31
Pages: 26-33
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27646277 | J:338277
First Author: Baeyens N
Year: 2016
Journal: J Cell Biol
Title: Defective fluid shear stress mechanotransduction mediates hereditary hemorrhagic telangiectasia.
Volume: 214
Issue: 7
Pages: 807-16
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Publication
32753679 | J:298813
First Author: Lora Gil C
Year: 2020
Journal: Sci Rep
Title: Alk1 haploinsufficiency causes glomerular dysfunction and microalbuminuria in diabetic mice.
Volume: 10
Issue: 1
Pages: 13136
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Publication
29880487 | J:285129
First Author: Akla N
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: BMP9 (Bone Morphogenetic Protein-9)/Alk1 (Activin-Like Kinase Receptor Type I) Signaling Prevents Hyperglycemia-Induced Vascular Permeability.
Volume: 38
Issue: 8
Pages: 1821-1836
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Publication
28339142 | J:339069
First Author: Kim YH
Year: 2017
Journal: J Thromb Haemost
Title: Selective effects of oral antiangiogenic tyrosine kinase inhibitors on an animal model of hereditary hemorrhagic telangiectasia.
Volume: 15
Issue: 6
Pages: 1095-1102
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Publication
23241407 | J:216904
First Author: Chen W
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Reduced mural cell coverage and impaired vessel integrity after angiogenic stimulation in the Alk1-deficient brain.
Volume: 33
Issue: 2
Pages: 305-10
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Publication
9264265 | J:42106
First Author: Roelen BA
Year: 1997
Journal: Dev Dyn
Title: Expression of ALK-1, a type 1 serine/threonine kinase receptor, coincides with sites of vasculogenesis and angiogenesis in early mouse development.
Volume: 209
Issue: 4
Pages: 418-30
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22421041 | J:182726
First Author: Larrivée B
Year: 2012
Journal: Dev Cell
Title: ALK1 signaling inhibits angiogenesis by cooperating with the Notch pathway.
Volume: 22
Issue: 3
Pages: 489-500
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Publication
34874921 | J:322626
 
First Author: Zhao D
Year: 2022
Journal: J Clin Invest
Title: ALK1 signaling is required for the homeostasis of Kupffer cells and prevention of bacterial infection.
Volume: 132
Issue: 3
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Publication
21765215 | J:176031
First Author: Yao Y
Year: 2011
Journal: J Clin Invest
Title: Matrix Gla protein deficiency causes arteriovenous malformations in mice.
Volume: 121
Issue: 8
Pages: 2993-3004
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Publication
25614167 | J:301857
First Author: Boström KI
Year: 2015
Journal: Eur Respir J
Title: Matrix Gla protein limits pulmonary arteriovenous malformations in ALK1 deficiency.
Volume: 45
Issue: 3
Pages: 849-52
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25538155 | J:251548
First Author: Moon EH
Year: 2015
Journal: Cardiovasc Res
Title: Essential role for TMEM100 in vascular integrity but limited contributions to the pathogenesis of hereditary haemorrhagic telangiectasia.
Volume: 105
Issue: 3
Pages: 353-60
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Publication
23048070 | J:212878
First Author: Garrido-Martín EM
Year: 2013
Journal: Circ Res
Title: Vascular injury triggers Krüppel-like factor 6 mobilization and cooperation with specificity protein 1 to promote endothelial activation through upregulation of the activin receptor-like kinase 1 gene.
Volume: 112
Issue: 1
Pages: 113-27
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Publication
37699906 | J:340555
First Author: Chovatiya G
Year: 2023
Journal: Nat Commun
Title: Alk1 acts in non-endothelial VE-cadherin(+) perineurial cells to maintain nerve branching during hair homeostasis.
Volume: 14
Issue: 1
Pages: 5623
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Publication
27352867 | J:315587
First Author: Ma L
Year: 2016
Journal: Transl Stroke Res
Title: Integrin β8 Deletion Enhances Vascular Dysplasia and Hemorrhage in the Brain of Adult Alk1 Heterozygous Mice.
Volume: 7
Issue: 6
Pages: 488-496
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Publication
23675457 | J:286684
First Author: Choi EJ
Year: 2013
Journal: PLoS One
Title: Enhanced responses to angiogenic cues underlie the pathogenesis of hereditary hemorrhagic telangiectasia 2.
Volume: 8
Issue: 5
Pages: e63138
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Publication
27869117 | J:243076
 
First Author: Kraehling JR
Year: 2016
Journal: Nat Commun
Title: Genome-wide RNAi screen reveals ALK1 mediates LDL uptake and transcytosis in endothelial cells.
Volume: 7
Pages: 13516
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Publication
25082229 | J:227170
First Author: Garrido-Martin EM
Year: 2014
Journal: Arterioscler Thromb Vasc Biol
Title: Common and distinctive pathogenetic features of arteriovenous malformations in hereditary hemorrhagic telangiectasia 1 and hereditary hemorrhagic telangiectasia 2 animal models--brief report.
Volume: 34
Issue: 10
Pages: 2232-6
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Publication
22474252 | J:185158
First Author: Yao Y
Year: 2012
Journal: Blood
Title: Crossveinless 2 regulates bone morphogenetic protein 9 in human and mouse vascular endothelium.
Volume: 119
Issue: 21
Pages: 5037-47
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Publication
29449337 | J:285174
First Author: Alsina-Sanchís E
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: ALK1 Loss Results in Vascular Hyperplasia in Mice and Humans Through PI3K Activation.
Volume: 38
Issue: 5
Pages: 1216-1229
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Publication
24594380 | J:211569
First Author: Muñoz-Félix JM
Year: 2014
Journal: Biochim Biophys Acta
Title: ALK1 heterozygosity increases extracellular matrix protein expression, proliferation and migration in fibroblasts.
Volume: 1843
Issue: 6
Pages: 1111-22
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Publication
25266657 | J:224324
First Author: Curado F
Year: 2014
Journal: Mol Cell Biol
Title: ALK5 and ALK1 play antagonistic roles in transforming growth factor β-induced podosome formation in aortic endothelial cells.
Volume: 34
Issue: 24
Pages: 4389-403
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Publication
31343406 | J:282467
   
First Author: Li KN
Year: 2019
Journal: Elife
Title: Skin vasculature and hair follicle cross-talking associated with stem cell activation and tissue homeostasis.
Volume: 8
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Publication
29976569 | J:289232
First Author: Ola R
Year: 2018
Journal: Circulation
Title: SMAD4 Prevents Flow Induced Arteriovenous Malformations by Inhibiting Casein Kinase 2.
Volume: 138
Issue: 21
Pages: 2379-2394
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Publication
32042114 | J:297792
First Author: Viallard C
Year: 2020
Journal: Oncogene
Title: BMP9 signaling promotes the normalization of tumor blood vessels.
Volume: 39
Issue: 14
Pages: 2996-3014
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Publication
35021063 | J:320004
First Author: Guilliams M
Year: 2022
Journal: Cell
Title: Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches.
Volume: 185
Issue: 2
Pages: 379-396.e38
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Publication
35663401 | J:325560
 
First Author: Edgar LT
Year: 2022
Journal: Front Cell Dev Biol
Title: Traffic Patterns of the Migrating Endothelium: How Force Transmission Regulates Vascular Malformation and Functional Shunting During Angiogenic Remodelling.
Volume: 10
Pages: 840066
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Publication
27741515 | J:312826
First Author: Eleftheriou NM
Year: 2016
Journal: Oncotarget
Title: Compound genetically engineered mouse models of cancer reveal dual targeting of ALK1 and endoglin as a synergistic opportunity to impinge on angiogenic TGF-β signaling.
Volume: 7
Issue: 51
Pages: 84314-84325
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7750489 | J:25936
First Author: Dewulf N
Year: 1995
Journal: Endocrinology
Title: Distinct spatial and temporal expression patterns of two type I receptors for bone morphogenetic proteins during mouse embryogenesis.
Volume: 136
Issue: 6
Pages: 2652-63
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Publication
12970115 | J:85877
First Author: Seki T
Year: 2003
Journal: Circ Res
Title: Arterial endothelium-specific activin receptor-like kinase 1 expression suggests its role in arterialization and vascular remodeling.
Volume: 93
Issue: 7
Pages: 682-9
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Publication
17911384 | J:130020
First Author: Park SO
Year: 2008
Journal: Blood
Title: ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2.
Volume: 111
Issue: 2
Pages: 633-42
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Publication
24061911 | J:345772
First Author: Ardelean DS
Year: 2014
Journal: Angiogenesis
Title: Endoglin and activin receptor-like kinase 1 heterozygous mice have a distinct pulmonary and hepatic angiogenic profile and response to anti-VEGF treatment.
Volume: 17
Issue: 1
Pages: 129-46
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Publication
24956016 | J:218855
First Author: Gore B
Year: 2014
Journal: PLoS One
Title: Key role of the endothelial TGF-β/ALK1/endoglin signaling pathway in humans and rodents pulmonary hypertension.
Volume: 9
Issue: 6
Pages: e100310
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15923183 | J:100819
First Author: Pece-Barbara N
Year: 2005
Journal: J Biol Chem
Title: Endoglin null endothelial cells proliferate faster and are more responsive to transforming growth factor beta1 with higher affinity receptors and an activated Alk1 pathway.
Volume: 280
Issue: 30
Pages: 27800-8
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Publication
30571376 | J:287210
First Author: Kim YH
Year: 2018
Journal: J Am Heart Assoc
Title: SMAD4 Deficiency Leads to Development of Arteriovenous Malformations in Neonatal and Adult Mice.
Volume: 7
Issue: 21
Pages: e009514
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Publication
26081042 | J:233547
 
First Author: Aspalter IM
Year: 2015
Journal: Nat Commun
Title: Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch.
Volume: 6
Pages: 7264
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24133138 | J:202927
First Author: Yoshimatsu Y
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Bone morphogenetic protein-9 inhibits lymphatic vessel formation via activin receptor-like kinase 1 during development and cancer progression.
Volume: 110
Issue: 47
Pages: 18940-5
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Publication
22571958 | J:196810
First Author: Choi EJ
Year: 2012
Journal: Cerebrovasc Dis
Title: Minimal homozygous endothelial deletion of Eng with VEGF stimulation is sufficient to cause cerebrovascular dysplasia in the adult mouse.
Volume: 33
Issue: 6
Pages: 540-7
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Publication
30165893 | J:338274
First Author: Ouarné M
Year: 2018
Journal: J Exp Clin Cancer Res
Title: BMP9, but not BMP10, acts as a quiescence factor on tumor growth, vessel normalization and metastasis in a mouse model of breast cancer.
Volume: 37
Issue: 1
Pages: 209
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Publication
27897192 | J:243169
 
First Author: Ola R
Year: 2016
Journal: Nat Commun
Title: PI3 kinase inhibition improves vascular malformations in mouse models of hereditary haemorrhagic telangiectasia.
Volume: 7
Pages: 13650
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Publication
19494318 | J:149284
First Author: Blaney Davidson EN
Year: 2009
Journal: J Immunol
Title: Increase in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in osteoarthritis in humans and mice.
Volume: 182
Issue: 12
Pages: 7937-45
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9547239 | J:47045
First Author: Zhang D
Year: 1998
Journal: J Neurosci
Title: Development of bone morphogenetic protein receptors in the nervous system and possible roles in regulating trkC expression.
Volume: 18
Issue: 9
Pages: 3314-26
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Publication
17967972 | J:142991
First Author: Korff T
Year: 2007
Journal: Circulation
Title: Cyclic stretch controls the expression of CD40 in endothelial cells by changing their transforming growth factor-beta1 response.
Volume: 116
Issue: 20
Pages: 2288-97
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20628059 | J:166395
First Author: Luo J
Year: 2010
Journal: J Biol Chem
Title: TGFbeta/BMP type I receptors ALK1 and ALK2 are essential for BMP9-induced osteogenic signaling in mesenchymal stem cells.
Volume: 285
Issue: 38
Pages: 29588-98
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27866969 | J:240045
First Author: Vorstenbosch J
Year: 2017
Journal: J Invest Dermatol
Title: Overexpression of CD109 in the Epidermis Differentially Regulates ALK1 Versus ALK5 Signaling and Modulates Extracellular Matrix Synthesis in the Skin.
Volume: 137
Issue: 3
Pages: 641-649
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Publication
36594096 | J:349832
First Author: Liu M
Year: 2023
Journal: Int J Biol Sci
Title: N-glycosylation-mediated CD147 accumulation induces cardiac fibrosis in the diabetic heart through ALK5 activation.
Volume: 19
Issue: 1
Pages: 137-155
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Publication
12941633 | J:85367
First Author: Park KW
Year: 2003
Journal: Dev Biol
Title: Robo4 is a vascular-specific receptor that inhibits endothelial migration.
Volume: 261
Issue: 1
Pages: 251-67
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17530030 | J:122868
First Author: Hong KH
Year: 2007
Journal: Lab Invest
Title: Activin receptor-like kinase 1 is essential for placental vascular development in mice.
Volume: 87
Issue: 7
Pages: 670-9
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16344855 | J:104918
First Author: Seki T
Year: 2006
Journal: Lab Invest
Title: Nonoverlapping expression patterns of ALK1 and ALK5 reveal distinct roles of each receptor in vascular development.
Volume: 86
Issue: 2
Pages: 116-29
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12941632 | J:85366
First Author: Sorensen LK
Year: 2003
Journal: Dev Biol
Title: Loss of distinct arterial and venous boundaries in mice lacking endoglin, a vascular-specific TGFbeta coreceptor.
Volume: 261
Issue: 1
Pages: 235-50
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Publication
28232325 | J:263613
First Author: Lee HW
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: Alk2/ACVR1 and Alk3/BMPR1A Provide Essential Function for Bone Morphogenetic Protein-Induced Retinal Angiogenesis.
Volume: 37
Issue: 4
Pages: 657-663
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26873969 | J:232934
First Author: Shahid M
Year: 2016
Journal: Am J Physiol Heart Circ Physiol
Title: BMP type I receptor ALK2 is required for angiotensin II-induced cardiac hypertrophy.
Volume: 310
Issue: 8
Pages: H984-94
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29478089 | J:262893
First Author: Araki M
Year: 2018
Journal: Angiogenesis
Title: Serum/glucocorticoid-regulated kinase 1 as a novel transcriptional target of bone morphogenetic protein-ALK1 receptor signaling in vascular endothelial cells.
Volume: 21
Issue: 2
Pages: 415-423
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19903896 | J:157791
First Author: Niessen K
Year: 2010
Journal: Blood
Title: ALK1 signaling regulates early postnatal lymphatic vessel development.
Volume: 115
Issue: 8
Pages: 1654-61
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Publication
31719172 | J:293202
 
First Author: Morikawa M
Year: 2019
Journal: Sci Signal
Title: The ALK-1/SMAD/ATOH8 axis attenuates hypoxic responses and protects against the development of pulmonary arterial hypertension.
Volume: 12
Issue: 607
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Publication
16862160 | J:111629
First Author: Liu P
Year: 2006
Journal: Nat Genet
Title: Candidate lung tumor susceptibility genes identified through whole-genome association analyses in inbred mice.
Volume: 38
Issue: 8
Pages: 888-95
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23868260 | J:204744
First Author: Wang X
Year: 2013
Journal: Nature
Title: LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling.
Volume: 499
Issue: 7458
Pages: 306-11
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Publication
10716993 | J:61177
First Author: Oh SP
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis.
Volume: 97
Issue: 6
Pages: 2626-31
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Publication
26659946 | J:239043
First Author: Dubrac A
Year: 2016
Journal: Circulation
Title: Targeting NCK-Mediated Endothelial Cell Front-Rear Polarity Inhibits Neovascularization.
Volume: 133
Issue: 4
Pages: 409-21
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Publication
14580334 | J:86237
First Author: Goumans MJ
Year: 2003
Journal: Mol Cell
Title: Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling.
Volume: 12
Issue: 4
Pages: 817-28
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14729481 | J:87407
First Author: Dudas M
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