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Search results 1 to 100 out of 226 for Angpt1

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Category: Publication
Type Details Score
Publication
First Author: Gale NW
Year: 2002
Journal: Dev Cell
Title: Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1.
Volume: 3
Issue: 3
Pages: 411-23
Publication
First Author: Brindle NP
Year: 2006
Journal: Circ Res
Title: Signaling and functions of angiopoietin-1 in vascular protection.
Volume: 98
Issue: 8
Pages: 1014-23
Publication
First Author: Kostallari E
Year: 2015
Journal: Development
Title: Pericytes in the myovascular niche promote post-natal myofiber growth and satellite cell quiescence.
Volume: 142
Issue: 7
Pages: 1242-53
Publication  
First Author: Zhou BO
Year: 2015
Journal: Elife
Title: Hematopoietic stem and progenitor cells regulate the regeneration of their niche by secreting Angiopoietin-1.
Volume: 4
Pages: e05521
Publication
First Author: Loganathan K
Year: 2018
Journal: PLoS One
Title: Angiopoietin-1 deficiency increases renal capillary rarefaction and tubulointerstitial fibrosis in mice.
Volume: 13
Issue: 1
Pages: e0189433
Publication
First Author: Kapiainen E
Year: 2022
Journal: Invest Ophthalmol Vis Sci
Title: Cooperation of Angiopoietin-2 and Angiopoietin-4 in Schlemm's Canal Maintenance.
Volume: 63
Issue: 11
Pages: 1
Publication
First Author: Souma T
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Context-dependent functions of angiopoietin 2 are determined by the endothelial phosphatase VEPTP.
Volume: 115
Issue: 6
Pages: 1298-1303
Publication
First Author: Kim KH
Year: 2018
Journal: Cell Rep
Title: Myocardial Angiopoietin-1 Controls Atrial Chamber Morphogenesis by Spatiotemporal Degradation of Cardiac Jelly.
Volume: 23
Issue: 8
Pages: 2455-2466
Publication
First Author: Thomson BR
Year: 2021
Journal: Nat Commun
Title: Cellular crosstalk regulates the aqueous humor outflow pathway and provides new targets for glaucoma therapies.
Volume: 12
Issue: 1
Pages: 6072
Publication
First Author: Thomson BR
Year: 2014
Journal: J Clin Invest
Title: A lymphatic defect causes ocular hypertension and glaucoma in mice.
Volume: 124
Issue: 10
Pages: 4320-4
Publication
First Author: Liu P
Year: 2022
Journal: Arterioscler Thromb Vasc Biol
Title: Angiopoietin-1 Is Required for Vortex Vein and Choriocapillaris Development in Mice.
Volume: 42
Issue: 11
Pages: 1413-1427
Publication
First Author: Thomson BR
Year: 2017
Journal: J Clin Invest
Title: Angiopoietin-1 is required for Schlemm's canal development in mice and humans.
Volume: 127
Issue: 12
Pages: 4421-4436
Publication
First Author: Park HS
Year: 2019
Journal: Diabetes
Title: β-Cell-Derived Angiopoietin-1 Regulates Insulin Secretion and Glucose Homeostasis by Stabilizing the Islet Microenvironment.
Volume: 68
Issue: 4
Pages: 774-786
Publication
First Author: Ward NL
Year: 2005
Journal: J Comp Neurol
Title: Vascular-specific growth factor angiopoietin 1 is involved in the organization of neuronal processes.
Volume: 482
Issue: 3
Pages: 244-56
Publication
First Author: Higgins SJ
Year: 2016
Journal: Sci Transl Med
Title: Dysregulation of angiopoietin-1 plays a mechanistic role in the pathogenesis of cerebral malaria.
Volume: 8
Issue: 358
Pages: 358ra128
Publication
First Author: Lee J
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: Angiopoietin-1 suppresses choroidal neovascularization and vascular leakage.
Volume: 55
Issue: 4
Pages: 2191-9
Publication
First Author: Singh S
Year: 2016
Journal: PLoS One
Title: Tubular Overexpression of Angiopoietin-1 Attenuates Renal Fibrosis.
Volume: 11
Issue: 7
Pages: e0158908
Publication
First Author: Serghides L
Year: 2014
Journal: PLoS Pathog
Title: PPARγ agonists improve survival and neurocognitive outcomes in experimental cerebral malaria and induce neuroprotective pathways in human malaria.
Volume: 10
Issue: 3
Pages: e1003980
Publication
First Author: Daly C
Year: 2018
Journal: Sci Rep
Title: Angiopoietins bind thrombomodulin and inhibit its function as a thrombin cofactor.
Volume: 8
Issue: 1
Pages: 505
Publication
First Author: Ward NL
Year: 2004
Journal: Dev Dyn
Title: Angiopoietin 1 expression levels in the myocardium direct coronary vessel development.
Volume: 229
Issue: 3
Pages: 500-9
Publication
First Author: Nambu H
Year: 2005
Journal: J Cell Physiol
Title: Angiopoietin 1 prevents retinal detachment in an aggressive model of proliferative retinopathy, but has no effect on established neovascularization.
Volume: 204
Issue: 1
Pages: 227-35
Publication
First Author: Kim YM
Year: 2006
Journal: Cancer Res
Title: Hydrogen peroxide produced by angiopoietin-1 mediates angiogenesis.
Volume: 66
Issue: 12
Pages: 6167-74
Publication
First Author: Suzuki T
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Osteoblast-specific Angiopoietin 1 overexpression increases bone mass.
Volume: 362
Issue: 4
Pages: 1019-25
Publication
First Author: Dallabrida SM
Year: 2008
Journal: FASEB J
Title: Integrin binding angiopoietin-1 monomers reduce cardiac hypertrophy.
Volume: 22
Issue: 8
Pages: 3010-23
Publication
First Author: Youn SW
Year: 2011
Journal: Blood
Title: COMP-Ang1 stimulates HIF-1α-mediated SDF-1 overexpression and recovers ischemic injury through BM-derived progenitor cell recruitment.
Volume: 117
Issue: 16
Pages: 4376-86
Publication
First Author: Tang XD
Year: 2017
Journal: Stem Cells
Title: Mesenchymal Stem Cell Microvesicles Attenuate Acute Lung Injury in Mice Partly Mediated by Ang-1 mRNA.
Volume: 35
Issue: 7
Pages: 1849-1859
Publication
First Author: Ou X
Year: 2020
Journal: Biochim Biophys Acta Mol Cell Biol Lipids
Title: Angiopoietin-1 aggravates atherosclerosis by inhibiting cholesterol efflux and promoting inflammatory response.
Volume: 1865
Issue: 2
Pages: 158535
Publication
First Author: Chiang WC
Year: 2019
Journal: Mol Med
Title: Angiopoietin 1 influences ischemic reperfusion renal injury via modulating endothelium survival and regeneration.
Volume: 25
Issue: 1
Pages: 5
Publication
First Author: Moxon JV
Year: 2019
Journal: J Cereb Blood Flow Metab
Title: The effect of angiopoietin-1 upregulation on the outcome of acute ischaemic stroke in rodent models: A meta-analysis.
Volume: 39
Issue: 12
Pages: 2343-2354
Publication
First Author: Hammes HP
Year: 2004
Journal: Diabetes
Title: Angiopoietin-2 causes pericyte dropout in the normal retina: evidence for involvement in diabetic retinopathy.
Volume: 53
Issue: 4
Pages: 1104-10
Publication
First Author: Li X
Year: 2008
Journal: Blood
Title: Basal and angiopoietin-1-mediated endothelial permeability is regulated by sphingosine kinase-1.
Volume: 111
Issue: 7
Pages: 3489-97
Publication
First Author: Syed M
Year: 2017
Journal: Nat Commun
Title: Hyperoxia causes miR-34a-mediated injury via angiopoietin-1 in neonatal lungs.
Volume: 8
Issue: 1
Pages: 1173
Publication
First Author: Hess AP
Year: 2006
Journal: Reprod Fertil Dev
Title: Angiopoietin-1 and -2 mRNA and protein expression in mouse preimplantation embryos and uteri suggests a role in angiogenesis during implantation.
Volume: 18
Issue: 5
Pages: 509-16
Publication
First Author: Falcón BL
Year: 2009
Journal: Am J Pathol
Title: Contrasting actions of selective inhibitors of angiopoietin-1 and angiopoietin-2 on the normalization of tumor blood vessels.
Volume: 175
Issue: 5
Pages: 2159-70
Publication
First Author: Pietilä R
Year: 2012
Journal: J Cell Sci
Title: Ligand oligomerization state controls Tie2 receptor trafficking and angiopoietin-2-specific responses.
Volume: 125
Issue: Pt 9
Pages: 2212-23
Publication
First Author: Davis S
Year: 1996
Journal: Cell
Title: Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning.
Volume: 87
Issue: 7
Pages: 1161-9
Publication
First Author: Park JS
Year: 2016
Journal: Cancer Cell
Title: Normalization of Tumor Vessels by Tie2 Activation and Ang2 Inhibition Enhances Drug Delivery and Produces a Favorable Tumor Microenvironment.
Volume: 30
Issue: 6
Pages: 953-967
Publication
First Author: Ikushima YM
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Enhanced Angpt1/Tie2 signaling affects the differentiation and long-term repopulation ability of hematopoietic stem cells.
Volume: 430
Issue: 1
Pages: 20-5
Publication
First Author: Lee J
Year: 2013
Journal: Sci Transl Med
Title: Angiopoietin-1 guides directional angiogenesis through integrin αvβ5 signaling for recovery of ischemic retinopathy.
Volume: 5
Issue: 203
Pages: 203ra127
Publication
First Author: Michael IP
Year: 2017
Journal: BMC Cancer
Title: Angiopoietin-1 deficiency increases tumor metastasis in mice.
Volume: 17
Issue: 1
Pages: 539
Publication
First Author: Braun LJ
Year: 2020
Journal: Blood
Title: Platelets docking to VWF prevent leaks during leukocyte extravasation by stimulating Tie-2.
Volume: 136
Issue: 5
Pages: 627-639
Publication
First Author: Thurston G
Year: 1999
Journal: Science
Title: Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1.
Volume: 286
Issue: 5449
Pages: 2511-4
Publication
First Author: Griffin ME
Year: 2021
Journal: Nat Chem Biol
Title: Sulfated glycans engage the Ang-Tie pathway to regulate vascular development.
Volume: 17
Issue: 2
Pages: 178-186
Publication
First Author: Arai F
Year: 2004
Journal: Cell
Title: Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche.
Volume: 118
Issue: 2
Pages: 149-61
Publication
First Author: Sabirzhanov B
Year: 2019
Journal: Cell Death Dis
Title: Inhibition of microRNA-711 limits angiopoietin-1 and Akt changes, tissue damage, and motor dysfunction after contusive spinal cord injury in mice.
Volume: 10
Issue: 11
Pages: 839
Publication
First Author: Suri C
Year: 1996
Journal: Cell
Title: Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis.
Volume: 87
Issue: 7
Pages: 1171-80
Publication
First Author: Kawai T
Year: 2002
Journal: Biosci Biotechnol Biochem
Title: Molecular cloning of mouse collectin liver 1.
Volume: 66
Issue: 10
Pages: 2134-45
Publication
First Author: Cui X
Year: 2011
Journal: Neurobiol Dis
Title: Angiopoietin/Tie2 pathway mediates type 2 diabetes induced vascular damage after cerebral stroke.
Volume: 43
Issue: 1
Pages: 285-92
Publication
First Author: Luck R
Year: 2021
Journal: Cell Rep
Title: The angiopoietin-Tie2 pathway regulates Purkinje cell dendritic morphogenesis in a cell-autonomous manner.
Volume: 36
Issue: 7
Pages: 109522
Publication
First Author: Kim J
Year: 2019
Journal: Sci Adv
Title: Tie2 activation promotes choriocapillary regeneration for alleviating neovascular age-related macular degeneration.
Volume: 5
Issue: 2
Pages: eaau6732
Publication
First Author: Hato T
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Angiopoietins contribute to lung development by regulating pulmonary vascular network formation.
Volume: 381
Issue: 2
Pages: 218-23
Publication
First Author: Kather JN
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: Angiopoietin-1 is regulated by miR-204 and contributes to corneal neovascularization in KLEIP-deficient mice.
Volume: 55
Issue: 7
Pages: 4295-303
Publication
First Author: Bai Y
Year: 2009
Journal: Neuroscience
Title: An Ang1-Tie2-PI3K axis in neural progenitor cells initiates survival responses against oxygen and glucose deprivation.
Volume: 160
Issue: 2
Pages: 371-81
Publication
First Author: Pham VN
Year: 2001
Journal: Dev Dyn
Title: Isolation and expression analysis of three zebrafish angiopoietin genes.
Volume: 221
Issue: 4
Pages: 470-4
Publication
First Author: Colen KL
Year: 1999
Journal: J Pediatr Surg
Title: Vascular development in the mouse embryonic pancreas and lung.
Volume: 34
Issue: 5
Pages: 781-5
Publication
First Author: Chinoy MR
Year: 2002
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Angiopoietin-1 and VEGF in vascular development and angiogenesis in hypoplastic lungs.
Volume: 283
Issue: 1
Pages: L60-6
Publication
First Author: Fuxe J
Year: 2011
Journal: Am J Pathol
Title: Pericyte requirement for anti-leak action of angiopoietin-1 and vascular remodeling in sustained inflammation.
Volume: 178
Issue: 6
Pages: 2897-909
Publication
First Author: Yamakawa D
Year: 2013
Journal: J Biol Chem
Title: Ligand-independent Tie2 dimers mediate kinase activity stimulated by high dose angiopoietin-1.
Volume: 288
Issue: 18
Pages: 12469-77
Publication
First Author: Brunckhorst MK
Year: 2014
Journal: Am J Pathol
Title: Angiopoietins promote ovarian cancer progression by establishing a procancer microenvironment.
Volume: 184
Issue: 8
Pages: 2285-96
Publication
First Author: Yin GN
Year: 2018
Journal: Diabetes
Title: Pericyte-Derived Dickkopf2 Regenerates Damaged Penile Neurovasculature Through an Angiopoietin-1-Tie2 Pathway.
Volume: 67
Issue: 6
Pages: 1149-1161
Publication
First Author: Maisonpierre PC
Year: 1997
Journal: Science
Title: Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis.
Volume: 277
Issue: 5322
Pages: 55-60
Publication
First Author: Abou-Khalil R
Year: 2009
Journal: Cell Stem Cell
Title: Autocrine and paracrine angiopoietin 1/Tie-2 signaling promotes muscle satellite cell self-renewal.
Volume: 5
Issue: 3
Pages: 298-309
Publication
First Author: Visconti RP
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Orchestration of angiogenesis and arteriovenous contribution by angiopoietins and vascular endothelial growth factor (VEGF).
Volume: 99
Issue: 12
Pages: 8219-24
Publication
First Author: Loughna S
Year: 2001
Journal: Mol Cell
Title: A combinatorial role of angiopoietin-1 and orphan receptor TIE1 pathways in establishing vascular polarity during angiogenesis.
Volume: 7
Issue: 1
Pages: 233-9
Publication
First Author: Pereira FA
Year: 1999
Journal: Genes Dev
Title: The orphan nuclear receptor COUP-TFII is required for angiogenesis and heart development.
Volume: 13
Issue: 8
Pages: 1037-49
Publication
First Author: Lee SJ
Year: 2018
Journal: J Clin Invest
Title: Angiopoietin-2 exacerbates cardiac hypoxia and inflammation after myocardial infarction.
Volume: 128
Issue: 11
Pages: 5018-5033
Publication
First Author: Mammoto T
Year: 2012
Journal: PLoS One
Title: LRP5 regulates development of lung microvessels and alveoli through the angiopoietin-Tie2 pathway.
Volume: 7
Issue: 7
Pages: e41596
Publication
First Author: Mitola S
Year: 2008
Journal: Blood
Title: Angiopoietin-1 mediates the proangiogenic activity of the bone morphogenic protein antagonist Drm.
Volume: 112
Issue: 4
Pages: 1154-7
Publication
First Author: Saunders WB
Year: 2006
Journal: J Cell Biol
Title: Coregulation of vascular tube stabilization by endothelial cell TIMP-2 and pericyte TIMP-3.
Volume: 175
Issue: 1
Pages: 179-91
Publication
First Author: Fuxe J
Year: 2010
Journal: Am J Pathol
Title: Angiopoietin/Tie2 signaling transforms capillaries into venules primed for leukocyte trafficking in airway inflammation.
Volume: 176
Issue: 4
Pages: 2009-18
Publication
First Author: Xia L
Year: 2004
Journal: J Cell Biol
Title: Defective angiogenesis and fatal embryonic hemorrhage in mice lacking core 1-derived O-glycans.
Volume: 164
Issue: 3
Pages: 451-9
Publication
First Author: Kertesz N
Year: 2004
Journal: Dev Biol
Title: The role of erythropoietin in regulating angiogenesis.
Volume: 276
Issue: 1
Pages: 101-10
Publication
First Author: Jang JY
Year: 2017
Journal: EMBO Mol Med
Title: VEGFR2 but not VEGFR3 governs integrity and remodeling of thyroid angiofollicular unit in normal state and during goitrogenesis.
Volume: 9
Issue: 6
Pages: 750-769
Publication
First Author: Takakura N
Year: 1998
Journal: Immunity
Title: Critical role of the TIE2 endothelial cell receptor in the development of definitive hematopoiesis.
Volume: 9
Issue: 5
Pages: 677-86
Publication
First Author: Patan S
Year: 1998
Journal: Microvasc Res
Title: TIE1 and TIE2 receptor tyrosine kinases inversely regulate embryonic angiogenesis by the mechanism of intussusceptive microvascular growth.
Volume: 56
Issue: 1
Pages: 1-21
Publication  
First Author: Park DY
Year: 2017
Journal: Nat Commun
Title: Plastic roles of pericytes in the blood-retinal barrier.
Volume: 8
Pages: 15296
Publication
First Author: Kamogawa J
Year: 2002
Journal: Arthritis Rheum
Title: Arthritis in MRL/lpr mice is under the control of multiple gene loci with an allelic combination derived from the original inbred strains.
Volume: 46
Issue: 4
Pages: 1067-74
Publication
First Author: Goossens S
Year: 2011
Journal: Blood
Title: The EMT regulator Zeb2/Sip1 is essential for murine embryonic hematopoietic stem/progenitor cell differentiation and mobilization.
Volume: 117
Issue: 21
Pages: 5620-30
Publication
First Author: Kim J
Year: 2017
Journal: J Clin Invest
Title: Impaired angiopoietin/Tie2 signaling compromises Schlemm's canal integrity and induces glaucoma.
Volume: 127
Issue: 10
Pages: 3877-3896
Publication
First Author: Kato K
Year: 2018
Journal: Nat Commun
Title: Pulmonary pericytes regulate lung morphogenesis.
Volume: 9
Issue: 1
Pages: 2448
Publication
First Author: Gu H
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Angiopoietin-1/Tie2 signaling pathway inhibits lipopolysaccharide-induced activation of RAW264.7 macrophage cells.
Volume: 392
Issue: 2
Pages: 178-82
Publication
First Author: Kolatsi-Joannou M
Year: 2001
Journal: Dev Dyn
Title: Expression and potential role of angiopoietins and Tie-2 in early development of the mouse metanephros.
Volume: 222
Issue: 1
Pages: 120-6
Publication
First Author: Mammoto T
Year: 2007
Journal: J Biol Chem
Title: Angiopoietin-1 requires p190 RhoGAP to protect against vascular leakage in vivo.
Volume: 282
Issue: 33
Pages: 23910-8
Publication
First Author: Yuan HT
Year: 1999
Journal: J Am Soc Nephrol
Title: Expression of angiopoietin-1, angiopoietin-2, and the Tie-2 receptor tyrosine kinase during mouse kidney maturation.
Volume: 10
Issue: 8
Pages: 1722-36
Publication
First Author: Morisada T
Year: 2005
Journal: Blood
Title: Angiopoietin-1 promotes LYVE-1-positive lymphatic vessel formation.
Volume: 105
Issue: 12
Pages: 4649-56
Publication
First Author: Suzuki Y
Year: 2008
Journal: J Biochem
Title: BMPs promote proliferation and migration of endothelial cells via stimulation of VEGF-A/VEGFR2 and angiopoietin-1/Tie2 signalling.
Volume: 143
Issue: 2
Pages: 199-206
Publication
First Author: Grzenda A
Year: 2013
Journal: Dis Model Mech
Title: Timing and expression of the angiopoietin-1-Tie-2 pathway in murine lung development and congenital diaphragmatic hernia.
Volume: 6
Issue: 1
Pages: 106-14
Publication
First Author: Han RN
Year: 2004
Journal: Circ Res
Title: Defective lung vascular development and fatal respiratory distress in endothelial NO synthase-deficient mice: a model of alveolar capillary dysplasia?
Volume: 94
Issue: 8
Pages: 1115-23
Publication
First Author: Ramírez-Bergeron DL
Year: 2006
Journal: Dev Cell
Title: HIF-dependent hematopoietic factors regulate the development of the embryonic vasculature.
Volume: 11
Issue: 1
Pages: 81-92
Publication
First Author: Abbott BD
Year: 2000
Journal: Dev Dyn
Title: Placental defects in ARNT-knockout conceptus correlate with localized decreases in VEGF-R2, Ang-1, and Tie-2.
Volume: 219
Issue: 4
Pages: 526-38
Publication
First Author: Baudino TA
Year: 2002
Journal: Genes Dev
Title: c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression.
Volume: 16
Issue: 19
Pages: 2530-43
Publication  
First Author: Courtney JA
Year: 2021
Journal: Int J Mol Sci
Title: Conditional Mutation of Hand1 in the Mouse Placenta Disrupts Placental Vascular Development Resulting in Fetal Loss in Both Early and Late Pregnancy.
Volume: 22
Issue: 17
Publication
First Author: Zhao Q
Year: 2011
Journal: Dev Biol
Title: Developmental ablation of Id1 and Id3 genes in the vasculature leads to postnatal cardiac phenotypes.
Volume: 349
Issue: 1
Pages: 53-64
Publication
First Author: Pitera JE
Year: 2004
Journal: Am J Pathol
Title: Dysmorphogenesis of kidney cortical peritubular capillaries in angiopoietin-2-deficient mice.
Volume: 165
Issue: 6
Pages: 1895-906
Publication
First Author: Desai SB
Year: 1999
Journal: J Immunother
Title: Tumor angiogenesis and endothelial cell modulatory factors.
Volume: 22
Issue: 3
Pages: 186-211
Publication
First Author: Hidai C
Year: 2005
Journal: Anat Rec A Discov Mol Cell Evol Biol
Title: Overexpression of the Del1 gene causes dendritic branching in the mouse mesentery.
Volume: 287
Issue: 2
Pages: 1165-75
Publication
First Author: Kawahara M
Year: 2010
Journal: J Reprod Dev
Title: Involvement of insulin-like growth factor 2 in angiogenic factor transcription in Bi-maternal mouse conceptuses.
Volume: 56
Issue: 1
Pages: 79-85
Publication
First Author: Sekimoto A
Year: 2024
Journal: iScience
Title: Impacts of low birthweight on kidney development and intergenerational growth of the offspring.
Volume: 27
Issue: 11
Pages: 111159
Publication
First Author: Yuasa H
Year: 2005
Journal: EMBO J
Title: Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression.
Volume: 24
Issue: 11
Pages: 1976-87
Publication
First Author: Lin Q
Year: 1998
Journal: Development
Title: Requirement of the MADS-box transcription factor MEF2C for vascular development.
Volume: 125
Issue: 22
Pages: 4565-74