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Search results 1 to 100 out of 183 for Apaf1

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Category: Publication
Type Details Score
Publication
First Author: Yoshida H
Year: 1998
Journal: Cell
Title: Apaf1 is required for mitochondrial pathways of apoptosis and brain development.
Volume: 94
Issue: 6
Pages: 739-50
Publication
First Author: Long AB
Year: 2013
Journal: Cell Death Differ
Title: Apaf1 apoptotic function critically limits Sonic hedgehog signaling during craniofacial development.
Volume: 20
Issue: 11
Pages: 1510-20
Publication
First Author: Cecconi F
Year: 1998
Journal: Cell
Title: Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development.
Volume: 94
Issue: 6
Pages: 727-37
Publication  
First Author: Sancho M
Year: 2014
Journal: Neuroscience
Title: Inactivation of Apaf1 reduces the formation of mutant huntingtin-dependent aggregates and cell death.
Volume: 262
Pages: 83-91
Publication
First Author: De Zio D
Year: 2011
Journal: Cell Death Differ
Title: The DNA repair complex Ku70/86 modulates Apaf1 expression upon DNA damage.
Volume: 18
Issue: 3
Pages: 516-27
Publication
First Author: Tong H
Year: 2018
Journal: PLoS One
Title: Apaf1 plays a negative regulatory role in T cell responses by suppressing activation of antigen-stimulated T cells.
Volume: 13
Issue: 3
Pages: e0195119
Publication
First Author: Müller M
Year: 2005
Journal: Dev Dyn
Title: Localization of Apaf1 gene expression in the early development of the mouse by means of in situ reverse transcriptase-polymerase chain reaction.
Volume: 234
Issue: 1
Pages: 215-21
Publication
First Author: Cho DH
Year: 2004
Journal: J Biol Chem
Title: Induced inhibition of ischemic/hypoxic injury by APIP, a novel Apaf-1-interacting protein.
Volume: 279
Issue: 38
Pages: 39942-50
Publication
First Author: Shiraishi H
Year: 2010
Journal: Biochim Biophys Acta
Title: Alternative cell death of Apaf1-deficient neural progenitor cells induced by withdrawal of EGF or insulin.
Volume: 1800
Issue: 3
Pages: 405-15
Publication
First Author: Joza N
Year: 2001
Journal: Nature
Title: Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death.
Volume: 410
Issue: 6828
Pages: 549-54
Publication
First Author: Chautan M
Year: 1999
Journal: Curr Biol
Title: Interdigital cell death can occur through a necrotic and caspase-independent pathway.
Volume: 9
Issue: 17
Pages: 967-70
Publication
First Author: Hara H
Year: 2002
Journal: J Immunol
Title: The apoptotic protease-activating factor 1-mediated pathway of apoptosis is dispensable for negative selection of thymocytes.
Volume: 168
Issue: 5
Pages: 2288-95
Publication
First Author: Okamoto H
Year: 2006
Journal: Cell Death Differ
Title: Histological analyses of normally grown, fertile Apaf1-deficient mice.
Volume: 13
Issue: 4
Pages: 668-71
Publication
First Author: Lüers GH
Year: 2002
Journal: Mech Dev
Title: Murine calmodulin binding protein 1 (Calmbp1): tissue-specific expression during development and in adult tissues.
Volume: 118
Issue: 1-2
Pages: 229-32
Publication
First Author: Honarpour N
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Apaf-1 deficiency and neural tube closure defects are found in fog mice.
Volume: 98
Issue: 17
Pages: 9683-7
Publication
First Author: Harris BS
Year: 1997
Journal: Teratology
Title: Forebrain overgrowth (fog): a new mutation in the mouse affecting neural tube development.
Volume: 55
Issue: 4
Pages: 231-40
Publication
First Author: Hao Z
Year: 2005
Journal: Cell
Title: Specific ablation of the apoptotic functions of cytochrome C reveals a differential requirement for cytochrome C and Apaf-1 in apoptosis.
Volume: 121
Issue: 4
Pages: 579-91
Publication
First Author: Honarpour N
Year: 2000
Journal: Dev Biol
Title: Adult Apaf-1-deficient mice exhibit male infertility.
Volume: 218
Issue: 2
Pages: 248-58
Publication
First Author: Thompson LF
Year: 2000
Journal: J Clin Invest
Title: Metabolites from apoptotic thymocytes inhibit thymopoiesis in adenosine deaminase-deficient fetal thymic organ cultures.
Volume: 106
Issue: 9
Pages: 1149-57
Publication
First Author: Yamaguchi Y
Year: 2011
Journal: J Cell Biol
Title: Live imaging of apoptosis in a novel transgenic mouse highlights its role in neural tube closure.
Volume: 195
Issue: 6
Pages: 1047-60
Publication
First Author: Armstrong PA
Year: 2015
Journal: Exp Brain Res
Title: Preserved otolith organ function in caspase-3-deficient mice with impaired horizontal semicircular canal function.
Volume: 233
Issue: 6
Pages: 1825-35
Publication
First Author: Imao T
Year: 2013
Journal: Cell Death Differ
Title: Apaf-1- and Caspase-8-independent apoptosis.
Volume: 20
Issue: 2
Pages: 343-52
Publication
First Author: Matsumoto Y
Year: 2020
Journal: Dev Biol
Title: Apoptosis is involved in maintaining the character of the midbrain and the diencephalon roof plate after neural tube closure.
Volume: 468
Issue: 1-2
Pages: 101-109
Publication
First Author: Nagasaka A
Year: 2010
Journal: Cell Death Differ
Title: Apaf-1-independent programmed cell death in mouse development.
Volume: 17
Issue: 6
Pages: 931-41
Publication
First Author: Ho AT
Year: 2007
Journal: Mol Cell Biol
Title: XIAP activity dictates Apaf-1 dependency for caspase 9 activation.
Volume: 27
Issue: 16
Pages: 5673-85
Publication
First Author: Van De Wiele CJ
Year: 2006
Journal: J Immunol
Title: Further differentiation of murine double-positive thymocytes is inhibited in adenosine deaminase-deficient murine fetal thymic organ culture.
Volume: 176
Issue: 10
Pages: 5925-33
Publication
First Author: Lindenboim L
Year: 2005
Journal: Cell Death Differ
Title: Bak but not Bax is essential for Bcl-xS-induced apoptosis.
Volume: 12
Issue: 7
Pages: 713-23
Publication
First Author: Ruiz-Vela A
Year: 2005
Journal: EMBO Rep
Title: Proapoptotic BAX and BAK control multiple initiator caspases.
Volume: 6
Issue: 4
Pages: 379-85
Publication
First Author: Ohsawa S
Year: 2008
Journal: Cell Death Differ
Title: Caspase-mediated changes in histone H1 in early apoptosis: prolonged caspase activation in developing olfactory sensory neurons.
Volume: 15
Issue: 9
Pages: 1429-39
Publication    
First Author: Fogel JL
Year: 2017
Journal: Elife
Title: A minimally sufficient model for rib proximal-distal patterning based on genetic analysis and agent-based simulations.
Volume: 6
Publication
First Author: Sancho M
Year: 2014
Journal: PLoS One
Title: Altered mitochondria morphology and cell metabolism in Apaf1-deficient cells.
Volume: 9
Issue: 1
Pages: e84666
Publication
First Author: Ohsawa S
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Maturation of the olfactory sensory neurons by Apaf-1/caspase-9-mediated caspase activity.
Volume: 107
Issue: 30
Pages: 13366-71
Publication
First Author: Nonomura K
Year: 2013
Journal: Dev Cell
Title: Local apoptosis modulates early mammalian brain development through the elimination of morphogen-producing cells.
Volume: 27
Issue: 6
Pages: 621-34
Publication
First Author: Teague JE
Year: 2010
Journal: J Immunol
Title: Proximal events in 7,12-dimethylbenz[a]anthracene-induced, stromal cell-dependent bone marrow B cell apoptosis: stromal cell-B cell communication and apoptosis signaling.
Volume: 185
Issue: 6
Pages: 3369-78
Publication
First Author: Rongvaux A
Year: 2014
Journal: Cell
Title: Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA.
Volume: 159
Issue: 7
Pages: 1563-77
Publication
First Author: Massa V
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Apoptosis is not required for mammalian neural tube closure.
Volume: 106
Issue: 20
Pages: 8233-8
Publication
First Author: Lu EP
Year: 2014
Journal: Blood
Title: Caspase-9 is required for normal hematopoietic development and protection from alkylator-induced DNA damage in mice.
Volume: 124
Issue: 26
Pages: 3887-95
Publication
First Author: Herrera VL
Year: 2009
Journal: Autophagy
Title: Autophagy: insights from DEspR-deficiency and haploinsufficiency.
Volume: 5
Issue: 2
Pages: 259-62
Publication
First Author: Oppenheim RW
Year: 2008
Journal: J Neurosci
Title: Developing postmitotic mammalian neurons in vivo lacking Apaf-1 undergo programmed cell death by a caspase-independent, nonapoptotic pathway involving autophagy.
Volume: 28
Issue: 6
Pages: 1490-7
Publication
First Author: Hisatomi T
Year: 2008
Journal: J Clin Invest
Title: HIV protease inhibitors provide neuroprotection through inhibition of mitochondrial apoptosis in mice.
Volume: 118
Issue: 6
Pages: 2025-38
Publication
First Author: Guo Z
Year: 2001
Journal: Cancer Res
Title: Inactivation of the retinoblastoma tumor suppressor induces apoptosis protease-activating factor-1 dependent and independent apoptotic pathways during embryogenesis.
Volume: 61
Issue: 23
Pages: 8395-400
Publication
First Author: Ioannides AS
Year: 2010
Journal: Dev Biol
Title: Foregut separation and tracheo-oesophageal malformations: the role of tracheal outgrowth, dorso-ventral patterning and programmed cell death.
Volume: 337
Issue: 2
Pages: 351-62
Publication
First Author: Cecconi F
Year: 2004
Journal: Development
Title: Apaf1-dependent programmed cell death is required for inner ear morphogenesis and growth.
Volume: 131
Issue: 9
Pages: 2125-35
Publication
First Author: Cozzolino M
Year: 2004
Journal: Cell Death Differ
Title: Apoptosome inactivation rescues proneural and neural cells from neurodegeneration.
Volume: 11
Issue: 11
Pages: 1179-91
Publication
First Author: De Zio D
Year: 2015
Journal: Cell Mol Life Sci
Title: Apaf1-deficient cortical neurons exhibit defects in axonal outgrowth.
Volume: 72
Issue: 21
Pages: 4173-91
Publication  
First Author: Josefsson EC
Year: 2014
Journal: Nat Commun
Title: Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways.
Volume: 5
Pages: 3455
Publication
First Author: Chinnam M
Year: 2016
Journal: Mol Cell Biol
Title: Evaluating Effects of Hypomorphic Thoc1 Alleles on Embryonic Development in Rb1 Null Mice.
Volume: 36
Issue: 11
Pages: 1621-7
Publication
First Author: Wikenheiser-Brokamp KA
Year: 2006
Journal: Cell Mol Life Sci
Title: Retinoblastoma family proteins: insights gained through genetic manipulation of mice.
Volume: 63
Issue: 7-8
Pages: 767-80
Publication
First Author: Mantela J
Year: 2005
Journal: Development
Title: The retinoblastoma gene pathway regulates the postmitotic state of hair cells of the mouse inner ear.
Volume: 132
Issue: 10
Pages: 2377-88
Publication
First Author: Sanchez-Olea R
Year: 2008
Journal: J Biol Chem
Title: Parcs is a dual regulator of cell proliferation and apaf-1 function.
Volume: 283
Issue: 36
Pages: 24400-5
Publication
First Author: Matsuki Y
Year: 2002
Journal: Scand J Immunol
Title: Different role of Apaf-1 in positive selection, negative selection and death by neglect in foetal thymic organ culture.
Volume: 56
Issue: 2
Pages: 174-84
Publication
First Author: Lin ML
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Selective suicide of cross-presenting CD8+ dendritic cells by cytochrome c injection shows functional heterogeneity within this subset.
Volume: 105
Issue: 8
Pages: 3029-34
Publication
First Author: Di Sano F
Year: 2006
Journal: J Biol Chem
Title: Endoplasmic reticulum stress induces apoptosis by an apoptosome-dependent but caspase 12-independent mechanism.
Volume: 281
Issue: 5
Pages: 2693-700
Publication      
First Author: He Z
Year: 2012
Journal: MGI Direct Data Submission
Title: Direct Data Submission 2012/01/09
Publication
First Author: Robles R
Year: 1999
Journal: Endocrinology
Title: Localization, regulation and possible consequences of apoptotic protease-activating factor-1 (Apaf-1) expression in granulosa cells of the mouse ovary.
Volume: 140
Issue: 6
Pages: 2641-4
Publication
First Author: Cregan SP
Year: 2002
Journal: J Cell Biol
Title: Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death.
Volume: 158
Issue: 3
Pages: 507-17
Publication
First Author: Johnson CE
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Differential Apaf-1 levels allow cytochrome c to induce apoptosis in brain tumors but not in normal neural tissues.
Volume: 104
Issue: 52
Pages: 20820-5
Publication
First Author: Feng R
Year: 2012
Journal: Free Radic Biol Med
Title: Apaf-1 deficiency confers resistance to ultraviolet-induced apoptosis in mouse embryonic fibroblasts by disrupting reactive oxygen species amplification production and mitochondrial pathway.
Volume: 52
Issue: 5
Pages: 889-97
Publication
First Author: Li K
Year: 2000
Journal: Cell
Title: Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis.
Volume: 101
Issue: 4
Pages: 389-99
Publication
First Author: Shiraishi H
Year: 2006
Journal: J Cell Sci
Title: ER stress-induced apoptosis and caspase-12 activation occurs downstream of mitochondrial apoptosis involving Apaf-1.
Volume: 119
Issue: Pt 19
Pages: 3958-66
Publication
First Author: Piddubnyak V
Year: 2007
Journal: Cell Death Differ
Title: Positive regulation of apoptosis by HCA66, a new Apaf-1 interacting protein, and its putative role in the physiopathology of NF1 microdeletion syndrome patients.
Volume: 14
Issue: 6
Pages: 1222-33
Publication  
First Author: Chen Q
Year: 2014
Journal: Cell Death Dis
Title: MicroRNA-23a/b and microRNA-27a/b suppress Apaf-1 protein and alleviate hypoxia-induced neuronal apoptosis.
Volume: 5
Pages: e1132
Publication
First Author: Aiyer AR
Year: 2005
Journal: Dev Biol
Title: Loss of Apaf-1 leads to partial rescue of the HAND2-null phenotype.
Volume: 278
Issue: 1
Pages: 155-62
Publication
First Author: Marsden VS
Year: 2006
Journal: Blood
Title: Apaf-1 and caspase-9 are required for cytokine withdrawal-induced apoptosis of mast cells but dispensable for their functional and clonogenic death.
Volume: 107
Issue: 5
Pages: 1872-7
Publication
First Author: Wallace DM
Year: 2006
Journal: Invest Ophthalmol Vis Sci
Title: Histone deacetylase activity regulates apaf-1 and caspase 3 expression in the developing mouse retina.
Volume: 47
Issue: 7
Pages: 2765-72
Publication
First Author: Vasey DB
Year: 2011
Journal: Transgenic Res
Title: Spatial p21 expression profile in the mid-term mouse embryo.
Volume: 20
Issue: 1
Pages: 23-8
Publication
First Author: Chowdhury K
Year: 1997
Journal: Nucleic Acids Res
Title: Evidence for the stochastic integration of gene trap vectors into the mouse germline.
Volume: 25
Issue: 8
Pages: 1531-6
Publication
First Author: O'Reilly LA
Year: 2002
Journal: Cell Death Differ
Title: Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9.
Volume: 9
Issue: 8
Pages: 832-41
Publication
First Author: Cheung EC
Year: 2006
Journal: EMBO J
Title: Dissociating the dual roles of apoptosis-inducing factor in maintaining mitochondrial structure and apoptosis.
Volume: 25
Issue: 17
Pages: 4061-73
Publication
First Author: Gama V
Year: 2014
Journal: Sci Signal
Title: The E3 ligase PARC mediates the degradation of cytosolic cytochrome c to promote survival in neurons and cancer cells.
Volume: 7
Issue: 334
Pages: ra67
Publication
First Author: Kuida K
Year: 1998
Journal: Cell
Title: Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9.
Volume: 94
Issue: 3
Pages: 325-37
Publication
First Author: Zou H
Year: 1999
Journal: J Biol Chem
Title: An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9.
Volume: 274
Issue: 17
Pages: 11549-56
Publication
First Author: Stoka V
Year: 2006
Journal: FEBS Lett
Title: Differential regulation of the intrinsic pathway of apoptosis in brain and liver during ageing.
Volume: 580
Issue: 15
Pages: 3739-45
Publication
First Author: Kim EM
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Caspase-9 activation and Apaf-1 cleavage by MMP-3.
Volume: 453
Issue: 3
Pages: 563-8
Publication
First Author: Villunger A
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Negative selection of semimature CD4(+)8(-)HSA+ thymocytes requires the BH3-only protein Bim but is independent of death receptor signaling.
Volume: 101
Issue: 18
Pages: 7052-7
Publication
First Author: Smith MI
Year: 2007
Journal: Cell Death Differ
Title: Endoplasmic reticulum stress-induced apoptosis requires bax for commitment and Apaf-1 for execution in primary neurons.
Volume: 14
Issue: 5
Pages: 1011-9
Publication
First Author: Lin L
Year: 2006
Journal: Cell Death Differ
Title: p53, Apaf-1, caspase-3, and -9 are dispensable for Cdk5 activation during cell death.
Volume: 13
Issue: 1
Pages: 141-50
Publication
First Author: Cheung EC
Year: 2005
Journal: J Neurosci
Title: Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms.
Volume: 25
Issue: 6
Pages: 1324-34
Publication
First Author: Marsden VS
Year: 2002
Journal: Nature
Title: Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome.
Volume: 419
Issue: 6907
Pages: 634-7
Publication
First Author: Honarpour N
Year: 2001
Journal: Neuroscience
Title: Embryonic neuronal death due to neurotrophin and neurotransmitter deprivation occurs independent of Apaf-1.
Volume: 106
Issue: 2
Pages: 263-74
Publication
First Author: Wright KM
Year: 2007
Journal: Cell Death Differ
Title: Apoptosome dependent caspase-3 activation pathway is non-redundant and necessary for apoptosis in sympathetic neurons.
Volume: 14
Issue: 3
Pages: 625-33
Publication
First Author: Li J
Year: 2006
Journal: J Biol Chem
Title: Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53.
Volume: 281
Issue: 11
Pages: 7260-70
Publication
First Author: Sakai T
Year: 2004
Journal: J Biol Chem
Title: Nucling recruits Apaf-1/pro-caspase-9 complex for the induction of stress-induced apoptosis.
Volume: 279
Issue: 39
Pages: 41131-40
Publication
First Author: Gong W
Year: 2015
Journal: J Biol Chem
Title: Kelch Repeat and BTB Domain Containing Protein 5 (Kbtbd5) Regulates Skeletal Muscle Myogenesis through the E2F1-DP1 Complex.
Volume: 290
Issue: 24
Pages: 15350-61
Publication
First Author: Vaughn AE
Year: 2007
Journal: Cell Death Differ
Title: Essential postmitochondrial function of p53 uncovered in DNA damage-induced apoptosis in neurons.
Volume: 14
Issue: 5
Pages: 973-81
Publication
First Author: Steckley D
Year: 2007
Journal: J Neurosci
Title: Puma is a dominant regulator of oxidative stress induced Bax activation and neuronal apoptosis.
Volume: 27
Issue: 47
Pages: 12989-99
Publication
First Author: Akhtar RS
Year: 2006
Journal: Cell Death Differ
Title: Neural precursor cells possess multiple p53-dependent apoptotic pathways.
Volume: 13
Issue: 10
Pages: 1727-39
Publication
First Author: Vaux DL
Year: 1999
Journal: Cell
Title: Cell death in development.
Volume: 96
Issue: 2
Pages: 245-54
Publication
First Author: Colussi PA
Year: 1999
Journal: Immunol Cell Biol
Title: Targeted disruption of caspase genes in mice: what they tell us about the functions of individual caspases in apoptosis.
Volume: 77
Issue: 1
Pages: 58-63
Publication
First Author: Morita Y
Year: 1999
Journal: Dev Biol
Title: Oocyte apoptosis: like sand through an hourglass.
Volume: 213
Issue: 1
Pages: 1-17
Publication
First Author: Xu W
Year: 2021
Journal: Cell Metab
Title: Apaf-1 Pyroptosome Senses Mitochondrial Permeability Transition.
Volume: 33
Issue: 2
Pages: 424-436.e10
Publication
First Author: Tracy K
Year: 2007
Journal: Mol Cell Biol
Title: BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy.
Volume: 27
Issue: 17
Pages: 6229-42
Publication
First Author: Zhang J
Year: 2007
Journal: FEBS Lett
Title: Developmental silencing and independency from E2F of apoptotic gene expression in postmitotic tissues.
Volume: 581
Issue: 30
Pages: 5781-6
Publication
First Author: Los M
Year: 1999
Journal: Immunity
Title: The role of caspases in development, immunity, and apoptotic signal transduction: lessons from knockout mice.
Volume: 10
Issue: 6
Pages: 629-39
Publication
First Author: Bae KB
Year: 2011
Journal: Transgenic Res
Title: Overexpression of Jazf1 induces cardiac malformation through the upregulation of pro-apoptotic genes in mice.
Volume: 20
Issue: 5
Pages: 1019-31
Publication
First Author: Urbanek ME
Year: 2021
Journal: Sci Rep
Title: Genetic predisposition to tinnitus in the UK Biobank population.
Volume: 11
Issue: 1
Pages: 18150
Publication
First Author: Chatoo W
Year: 2009
Journal: J Neurosci
Title: The polycomb group gene Bmi1 regulates antioxidant defenses in neurons by repressing p53 pro-oxidant activity.
Volume: 29
Issue: 2
Pages: 529-42
Publication
First Author: Berube C
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD.
Volume: 102
Issue: 40
Pages: 14314-20
Publication
First Author: Rao RV
Year: 2004
Journal: J Biol Chem
Title: Molecular components of a cell death pathway activated by endoplasmic reticulum stress.
Volume: 279
Issue: 1
Pages: 177-87
Publication
First Author: Wang Y
Year: 2016
Journal: Development
Title: Syndecan 4 controls lymphatic vasculature remodeling during mouse embryonic development.
Volume: 143
Issue: 23
Pages: 4441-4451