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Search results 1 to 100 out of 114 for Atxn3

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Type Details Score
Publication
30231063 | J:265858
First Author: Zeng L
Year: 2018
Journal: PLoS One
Title: Loss of the Spinocerebellar Ataxia type 3 disease protein ATXN3 alters transcription of multiple signal transduction pathways.
Volume: 13
Issue: 9
Pages: e0204438
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Publication
17764659 | J:145048
First Author: Schmitt I
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Inactivation of the mouse Atxn3 (ataxin-3) gene increases protein ubiquitination.
Volume: 362
Issue: 3
Pages: 734-9
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Publication
- | J:197601
     
First Author: Paulson HL
Year: 2013
Journal: MGI Direct Data Submission
Title: Knock-in of an expanded CAG repeat into the Atxn3 gene
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Publication
20347968 | J:165379
First Author: Pastori V
Year: 2010
Journal: Biochim Biophys Acta
Title: CK2 and GSK3 phosphorylation on S29 controls wild-type ATXN3 nuclear uptake.
Volume: 1802
Issue: 7-8
Pages: 583-92
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Publication
28676741 | J:337631
 
First Author: Hsu JY
Year: 2017
Journal: Front Mol Neurosci
Title: The Truncated C-terminal Fragment of Mutant ATXN3 Disrupts Mitochondria Dynamics in Spinocerebellar Ataxia Type 3 Models.
Volume: 10
Pages: 196
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Publication
33176149 | J:299940
First Author: Toulis V
Year: 2020
Journal: Cell Rep
Title: The Deubiquitinating Enzyme Ataxin-3 Regulates Ciliogenesis and Phagocytosis in the Retina.
Volume: 33
Issue: 6
Pages: 108360
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Publication
22777893 | J:252036
First Author: Reina CP
Year: 2012
Journal: Cell Stress Chaperones
Title: Basal and stress-induced Hsp70 are modulated by ataxin-3.
Volume: 17
Issue: 6
Pages: 729-42
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Publication
36010688 | J:328148
 
First Author: Schuster KH
Year: 2022
Journal: Cells
Title: Pathogenetic Mechanisms Underlying Spinocerebellar Ataxia Type 3 Are Altered in Primary Oligodendrocyte Culture.
Volume: 11
Issue: 16
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Publication
37122622 | J:345987
 
First Author: Luo H
Year: 2023
Journal: Front Mol Neurosci
Title: Regional and age-dependent changes in ubiquitination in cellular and mouse models of spinocerebellar ataxia type 3.
Volume: 16
Pages: 1154203
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Publication
35042771 | J:346235
First Author: Schuster KH
Year: 2022
Journal: J Neurosci
Title: Impaired Oligodendrocyte Maturation Is an Early Feature in SCA3 Disease Pathogenesis.
Volume: 42
Issue: 8
Pages: 1604-1617
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Publication
28854700 | J:244808
First Author: Ramani B
Year: 2017
Journal: Hum Mol Genet
Title: Comparison of spinocerebellar ataxia type 3 mouse models identifies early gain-of-function, cell-autonomous transcriptional changes in oligodendrocytes.
Volume: 26
Issue: 17
Pages: 3362-3374
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Publication
30576445 | J:273648
First Author: Schmidt J
Year: 2019
Journal: Hum Mol Genet
Title: Vulnerability of frontal brain neurons for the toxicity of expanded ataxin-3.
Volume: 28
Issue: 9
Pages: 1463-1473
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Publication
25301414 | J:218541
 
First Author: Switonski PM
Year: 2015
Journal: Neurobiol Dis
Title: A new humanized ataxin-3 knock-in mouse model combines the genetic features, pathogenesis of neurons and glia and late disease onset of SCA3/MJD.
Volume: 73
Pages: 174-88
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Publication
25320121 | J:219232
First Author: Ramani B
Year: 2015
Journal: Hum Mol Genet
Title: A knockin mouse model of spinocerebellar ataxia type 3 exhibits prominent aggregate pathology and aberrant splicing of the disease gene transcript.
Volume: 24
Issue: 5
Pages: 1211-24
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Publication
36875652 | J:345153
 
First Author: Schuster KH
Year: 2023
Journal: Front Neurosci
Title: Disease-associated oligodendrocyte signatures are spatiotemporally dysregulated in spinocerebellar ataxia type 3.
Volume: 17
Pages: 1118429
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Publication
20637808 | J:165449
First Author: Rodrigues AJ
Year: 2010
Journal: Biochim Biophys Acta
Title: Absence of ataxin-3 leads to cytoskeletal disorganization and increased cell death.
Volume: 1803
Issue: 10
Pages: 1154-63
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Publication
26505994 | J:244356
First Author: Esteves S
Year: 2015
Journal: PLoS One
Title: Limited Effect of Chronic Valproic Acid Treatment in a Mouse Model of Machado-Joseph Disease.
Volume: 10
Issue: 10
Pages: e0141610
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Publication
25143392 | J:216515
First Author: Neves-Carvalho A
Year: 2015
Journal: Hum Mol Genet
Title: Dominant negative effect of polyglutamine expansion perturbs normal function of ataxin-3 in neuronal cells.
Volume: 24
Issue: 1
Pages: 100-17
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Publication
32681165 | J:295993
First Author: Gerson JE
Year: 2020
Journal: Hum Mol Genet
Title: Ubiquilin-2 differentially regulates polyglutamine disease proteins.
Volume: 29
Issue: 15
Pages: 2596-2610
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Publication
20945165 | J:175960
First Author: Switonski PM
Year: 2011
Journal: Neuromolecular Med
Title: Mouse ataxin-3 functional knock-out model.
Volume: 13
Issue: 1
Pages: 54-65
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Publication
33741019 | J:325257
First Author: Sowa AS
Year: 2021
Journal: Mol Brain
Title: Neurodegenerative phosphoprotein signaling landscape in models of SCA3.
Volume: 14
Issue: 1
Pages: 57
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Publication
21060878 | J:166663
First Author: Harris GM
Year: 2010
Journal: PLoS One
Title: Splice isoforms of the polyglutamine disease protein ataxin-3 exhibit similar enzymatic yet different aggregation properties.
Volume: 5
Issue: 10
Pages: e13695
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Publication
11978767 | J:76495
First Author: Cemal CK
Year: 2002
Journal: Hum Mol Genet
Title: YAC transgenic mice carrying pathological alleles of the MJD1 locus exhibit a mild and slowly progressive cerebellar deficit.
Volume: 11
Issue: 9
Pages: 1075-94
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34716557 | J:338892
First Author: Haas E
Year: 2022
Journal: Mol Neurobiol
Title: A Novel SCA3 Knock-in Mouse Model Mimics the Human SCA3 Disease Phenotype Including Neuropathological, Behavioral, and Transcriptional Abnormalities Especially in Oligodendrocytes.
Volume: 59
Issue: 1
Pages: 495-522
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Publication
21653538 | J:185878
First Author: Hübener J
Year: 2011
Journal: Brain
Title: N-terminal ataxin-3 causes neurological symptoms with inclusions, endoplasmic reticulum stress and ribosomal dislocation.
Volume: 134
Issue: Pt 7
Pages: 1925-42
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Publication
30364204 | J:310818
 
First Author: Harmuth T
Year: 2018
Journal: Front Mol Neurosci
Title: Mitochondrial Morphology, Function and Homeostasis Are Impaired by Expression of an N-terminal Calpain Cleavage Fragment of Ataxin-3.
Volume: 11
Pages: 368
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Publication
18502140 | J:138381
First Author: Chou AH
Year: 2008
Journal: Neurobiol Dis
Title: Polyglutamine-expanded ataxin-3 causes cerebellar dysfunction of SCA3 transgenic mice by inducing transcriptional dysregulation.
Volume: 31
Issue: 1
Pages: 89-101
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Publication
17626202 | J:122993
First Author: Bichelmeier U
Year: 2007
Journal: J Neurosci
Title: Nuclear localization of ataxin-3 is required for the manifestation of symptoms in SCA3: in vivo evidence.
Volume: 27
Issue: 28
Pages: 7418-28
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Publication
22843411 | J:318907
First Author: Simões AT
Year: 2012
Journal: Brain
Title: Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado-Joseph disease.
Volume: 135
Issue: Pt 8
Pages: 2428-39
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Publication
23349684 | J:195850
First Author: Nóbrega C
Year: 2013
Journal: PLoS One
Title: Silencing mutant ataxin-3 rescues motor deficits and neuropathology in Machado-Joseph disease transgenic mice.
Volume: 8
Issue: 1
Pages: e52396
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Publication
34220448 | J:335361
 
First Author: Wiatr K
Year: 2021
Journal: Front Mol Neurosci
Title: Broad Influence of Mutant Ataxin-3 on the Proteome of the Adult Brain, Young Neurons, and Axons Reveals Central Molecular Processes and Biomarkers in SCA3/MJD Using Knock-In Mouse Model.
Volume: 14
Pages: 658339
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18353661 | J:136856
First Author: Pozzi C
Year: 2008
Journal: Neurobiol Dis
Title: Study of subcellular localization and proteolysis of ataxin-3.
Volume: 30
Issue: 2
Pages: 190-200
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Publication
19843543 | J:155356
First Author: Reina CP
Year: 2010
Journal: Hum Mol Genet
Title: Proteotoxic stress increases nuclear localization of ataxin-3.
Volume: 19
Issue: 2
Pages: 235-49
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8640226 | J:43217
First Author: Ikeda H
Year: 1996
Journal: Nat Genet
Title: Expanded polyglutamine in the Machado-Joseph disease protein induces cell death in vitro and in vivo.
Volume: 13
Issue: 2
Pages: 196-202
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Publication
17632007 | J:134822
First Author: Colomer Gould VF
Year: 2007
Journal: Neurobiol Dis
Title: A mutant ataxin-3 fragment results from processing at a site N-terminal to amino acid 190 in brain of Machado-Joseph disease-like transgenic mice.
Volume: 27
Issue: 3
Pages: 362-9
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20079840 | J:159934
First Author: Hübener J
Year: 2010
Journal: Neurobiol Dis
Title: Polyglutamine-induced neurodegeneration in SCA3 is not mitigated by non-expanded ataxin-3: conclusions from double-transgenic mouse models.
Volume: 38
Issue: 1
Pages: 116-24
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Publication
12486728 | J:80985
First Author: Albrecht M
Year: 2003
Journal: Proteins
Title: Structural modeling of ataxin-3 reveals distant homology to adaptins.
Volume: 50
Issue: 2
Pages: 355-70
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23100324 | J:191124
First Author: Hübener J
Year: 2013
Journal: Hum Mol Genet
Title: Calpain-mediated ataxin-3 cleavage in the molecular pathogenesis of spinocerebellar ataxia type 3 (SCA3).
Volume: 22
Issue: 3
Pages: 508-18
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28445460 | J:252513
First Author: Ashkenazi A
Year: 2017
Journal: Nature
Title: Polyglutamine tracts regulate beclin 1-dependent autophagy.
Volume: 545
Issue: 7652
Pages: 108-111
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21855799 | J:183193
First Author: Scaglione KM
Year: 2011
Journal: Mol Cell
Title: Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP.
Volume: 43
Issue: 4
Pages: 599-612
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7874163 | J:43214
First Author: Kawaguchi Y
Year: 1994
Journal: Nat Genet
Title: CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1.
Volume: 8
Issue: 3
Pages: 221-8
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10595501 | J:58566
First Author: Lin X
Year: 1999
Journal: Neuron
Title: Expanding our understanding of polyglutamine diseases through mouse models.
Volume: 24
Issue: 3
Pages: 499-502
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15233999 | J:91583
First Author: Costa MC
Year: 2004
Journal: Genomics
Title: Genomic structure, promoter activity, and developmental expression of the mouse homologue of the Machado-Joseph disease (MJD) gene.
Volume: 84
Issue: 2
Pages: 361-73
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Publication
20940148 | J:166727
First Author: Durcan TM
Year: 2011
Journal: Hum Mol Genet
Title: The Machado-Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability.
Volume: 20
Issue: 1
Pages: 141-54
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Publication
22761419 | J:329709
First Author: Wang H
Year: 2012
Journal: J Biol Chem
Title: Ataxin-3 regulates aggresome formation of copper-zinc superoxide dismutase (SOD1) by editing K63-linked polyubiquitin chains.
Volume: 287
Issue: 34
Pages: 28576-85
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27851749 | J:239749
First Author: Liu H
Year: 2016
Journal: PLoS Biol
Title: The Machado-Joseph Disease Deubiquitinase Ataxin-3 Regulates the Stability and Apoptotic Function of p53.
Volume: 14
Issue: 11
Pages: e2000733
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Publication
- | J:55472
     
First Author: Johnson KR
Year: 1999
Journal: Database Release
Title: JAX Mouse Mutant Resource (BSS) Backcross Panel Mapping Data
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16525503 | J:145209
First Author: Boeddrich A
Year: 2006
Journal: EMBO J
Title: An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis.
Volume: 25
Issue: 7
Pages: 1547-58
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Publication
16099943 | J:102671
First Author: Bewick GA
Year: 2005
Journal: FASEB J
Title: Post-embryonic ablation of AgRP neurons in mice leads to a lean, hypophagic phenotype.
Volume: 19
Issue: 12
Pages: 1680-2
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20668528 | J:163086
First Author: do Carmo Costa M
Year: 2010
Journal: PLoS One
Title: Ataxin-3 plays a role in mouse myogenic differentiation through regulation of integrin subunit levels.
Volume: 5
Issue: 7
Pages: e11728
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Publication
10860780 | J:64965
First Author: Orr HT
Year: 2000
Journal: Neurobiol Dis
Title: The ins and outs of a polyglutamine neurodegenerative disease: spinocerebellar ataxia type 1 (SCA1).
Volume: 7
Issue: 3
Pages: 129-34
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34815492 | J:314906
First Author: Khang R
Year: 2021
Journal: Sci Rep
Title: Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation.
Volume: 11
Issue: 1
Pages: 22745
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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First Author: Mouse Genome Informatics
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First Author: Mouse Genome Informatics Scientific Curators
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Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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First Author: Mouse Genome Informatics Scientific Curators
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Journal: Database Download
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Pages: 200-210
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First Author: Gao R
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Journal: PLoS Genet
Title: Inactivation of PNKP by mutant ATXN3 triggers apoptosis by activating the DNA damage-response pathway in SCA3.
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Pages: e1004834
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First Author: Yao Y
Year: 2020
Journal: Mol Cell
Title: Amino Acids Enhance Polyubiquitination of Rheb and Its Binding to mTORC1 by Blocking Lysosomal ATXN3 Deubiquitinase Activity.
Volume: 80
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Pages: 437-451.e6
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Journal: Biochem Biophys Res Commun
Title: A novel nuclear DnaJ protein, DNAJC8, can suppress the formation of spinocerebellar ataxia 3 polyglutamine aggregation in a J-domain independent manner.
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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