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Search results 1 to 100 out of 134 for Cflar

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Category: Publication
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Type Details Score
Publication
29107687 | J:250982
First Author: Zhuge B
Year: 2017
Journal: Biochem Biophys Res Commun
Title: MiR-150 deficiency ameliorated hepatosteatosis and insulin resistance in nonalcoholic fatty liver disease via targeting CASP8 and FADD-like apoptosis regulator.
Volume: 494
Issue: 3-4
Pages: 687-692
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Publication
28218919 | J:251277
First Author: Wang PX
Year: 2017
Journal: Nat Med
Title: Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates.
Volume: 23
Issue: 4
Pages: 439-449
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Publication
20100735 | J:158533
First Author: Lin YC
Year: 2010
Journal: Toxicol Sci
Title: FasL gene-deficient mice display a limited disruption in spermatogenesis and inhibition of mono-(2-ethylhexyl) phthalate-induced germ cell apoptosis.
Volume: 114
Issue: 2
Pages: 335-45
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Publication
26798068 | J:244556
First Author: Ram DR
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Balance between short and long isoforms of cFLIP regulates Fas-mediated apoptosis in vivo.
Volume: 113
Issue: 6
Pages: 1606-11
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Publication
11016460 | J:88667
First Author: Hill NJ
Year: 2000
Journal: Diabetes
Title: NOD Idd5 locus controls insulitis and diabetes and overlaps the orthologous CTLA4/IDDM12 and NRAMP1 loci in humans.
Volume: 49
Issue: 10
Pages: 1744-7
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Publication
31132747 | J:286073
 
First Author: Shindo R
Year: 2019
Journal: iScience
Title: Necroptosis of Intestinal Epithelial Cells Induces Type 3 Innate Lymphoid Cell-Dependent Lethal Ileitis.
Volume: 15
Pages: 536-551
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Publication
9289491 | J:42098
First Author: Goltsev YV
Year: 1997
Journal: J Biol Chem
Title: CASH, a novel caspase homologue with death effector domains.
Volume: 272
Issue: 32
Pages: 19641-4
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Publication
9217161 | J:41473
First Author: Irmler M
Year: 1997
Journal: Nature
Title: Inhibition of death receptor signals by cellular FLIP.
Volume: 388
Issue: 6638
Pages: 190-5
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Publication
20975036 | J:323312
First Author: Li H
Year: 2010
Journal: Hypertension
Title: Cellular FLICE-inhibitory protein protects against cardiac remodeling induced by angiotensin II in mice.
Volume: 56
Issue: 6
Pages: 1109-17
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Publication
23250397 | J:259529
First Author: Piao X
Year: 2012
Journal: Sci Signal
Title: c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis.
Volume: 5
Issue: 255
Pages: ra93
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Publication
39520684 | J:359835
First Author: Hong M
Year: 2024
Journal: Cell Rep
Title: Residue Y362 is crucial for FLIP(L) to impart catalytic activity to pro-caspase-8 to suppress necroptosis.
Volume: 43
Issue: 11
Pages: 114966
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Publication
16043517 | J:100558
First Author: Zhang N
Year: 2005
Journal: J Exp Med
Title: An essential role for c-FLIP in the efficient development of mature T lymphocytes.
Volume: 202
Issue: 3
Pages: 395-404
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Publication
23175183 | J:205617
First Author: He MX
Year: 2013
Journal: Cell Death Differ
Title: A role for c-FLIP(L) in the regulation of apoptosis, autophagy, and necroptosis in T lymphocytes.
Volume: 20
Issue: 2
Pages: 188-97
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Publication
24209745 | J:205130
First Author: Panayotova-Dimitrova D
Year: 2013
Journal: Cell Rep
Title: cFLIP regulates skin homeostasis and protects against TNF-induced keratinocyte apoptosis.
Volume: 5
Issue: 2
Pages: 397-408
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Publication
28850249 | J:269228
First Author: McCubbrey AL
Year: 2018
Journal: Am J Respir Cell Mol Biol
Title: Deletion of c-FLIP from CD11bhi Macrophages Prevents Development of Bleomycin-induced Lung Fibrosis.
Volume: 58
Issue: 1
Pages: 66-78
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Publication
18081036 | J:130528
First Author: Hinshaw-Makepeace J
Year: 2008
Journal: Eur J Immunol
Title: c-FLIP(S) reduces activation of caspase and NF-kappaB pathways and decreases T cell survival.
Volume: 38
Issue: 1
Pages: 54-63
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Publication
25342470 | J:258844
First Author: Gehrke N
Year: 2015
Journal: Cell Death Differ
Title: Acute organ failure following the loss of anti-apoptotic cellular FLICE-inhibitory protein involves activation of innate immune receptors.
Volume: 22
Issue: 5
Pages: 826-37
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Publication
29191940 | J:271426
First Author: Gehrke N
Year: 2018
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Loss of cellular FLICE-inhibitory protein promotes acute cholestatic liver injury and inflammation from bile duct ligation.
Volume: 314
Issue: 3
Pages: G319-G333
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Publication
38824526 | J:351982
First Author: Yang X
Year: 2024
Journal: J Neuroinflammation
Title: cFLIP in the molecular regulation of astroglia-driven neuroinflammation in experimental glaucoma.
Volume: 21
Issue: 1
Pages: 145
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Publication
21703207 | J:272080
First Author: Schattenberg JM
Year: 2011
Journal: J Hepatol
Title: Ablation of c-FLIP in hepatocytes enhances death-receptor mediated apoptosis and toxic liver injury in vivo.
Volume: 55
Issue: 6
Pages: 1272-80
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Publication
15761846 | J:97825
First Author: Oehme I
Year: 2005
Journal: Eur J Immunol
Title: Transgenic overexpression of the Caspase-8 inhibitor FLIP(short) leads to impaired T cell proliferation and an increased memory T cell pool after staphylococcal enterotoxin B injection.
Volume: 35
Issue: 4
Pages: 1240-9
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Publication
21364645 | J:228559
 
First Author: Giampietri C
Year: 2010
Journal: Cell Death Dis
Title: c-Flip overexpression affects satellite cell proliferation and promotes skeletal muscle aging.
Volume: 1
Pages: e38
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Publication
12135878 | J:78030
First Author: Xiao CW
Year: 2002
Journal: Biol Reprod
Title: Nuclear factor kappaB-mediated induction of Flice-like inhibitory protein prevents tumor necrosis factor alpha-induced apoptosis in rat granulosa cells.
Volume: 67
Issue: 2
Pages: 436-41
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Publication
15557152 | J:94365
First Author: Tseveleki V
Year: 2004
Journal: J Immunol
Title: Cellular FLIP (long isoform) overexpression in T cells drives Th2 effector responses and promotes immunoregulation in experimental autoimmune encephalomyelitis.
Volume: 173
Issue: 11
Pages: 6619-26
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Publication
15899875 | J:99102
First Author: Wang X
Year: 2005
Journal: Mol Cell Biol
Title: FLIP protects against hypoxia/reoxygenation-induced endothelial cell apoptosis by inhibiting Bax activation.
Volume: 25
Issue: 11
Pages: 4742-51
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Publication
17878261 | J:125510
First Author: Tseveleki V
Year: 2007
Journal: Int Immunol
Title: Cellular FLIP long isoform transgenic mice overcome inherent Th2-biased immune responses to efficiently resolve Leishmania major infection.
Volume: 19
Issue: 10
Pages: 1183-9
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17823262 | J:131134
First Author: Fang Y
Year: 2007
Journal: Endocrinology
Title: Expression of transgenic FLIP on thyroid epithelial cells inhibits induction and promotes resolution of granulomatous experimental autoimmune thyroiditis in CBA/J mice.
Volume: 148
Issue: 12
Pages: 5734-45
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Publication
18219316 | J:150996
First Author: Ueffing N
Year: 2008
Journal: Cell Death Differ
Title: Mutational analyses of c-FLIPR, the only murine short FLIP isoform, reveal requirements for DISC recruitment.
Volume: 15
Issue: 4
Pages: 773-82
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Publication
23505065 | J:198120
First Author: Telieps T
Year: 2013
Journal: Eur J Immunol
Title: Cellular-FLIP, Raji isoform (c-FLIP R) modulates cell death induction upon T-cell activation and infection.
Volume: 43
Issue: 6
Pages: 1499-510
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Publication
25746012 | J:230551
First Author: Giampietri C
Year: 2015
Journal: Biochim Biophys Acta
Title: c-Flip KO fibroblasts display lipid accumulation associated with endoplasmic reticulum stress.
Volume: 1851
Issue: 7
Pages: 929-36
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Publication
22202974 | J:330497
First Author: Xiao J
Year: 2012
Journal: Basic Res Cardiol
Title: Cellular FLICE-inhibitory protein protects against cardiac remodelling after myocardial infarction.
Volume: 107
Issue: 1
Pages: 239
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19109151 | J:143040
First Author: Zhang H
Year: 2009
Journal: J Immunol
Title: A role for cFLIP in B cell proliferation and stress MAPK regulation.
Volume: 182
Issue: 1
Pages: 207-15
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Publication
20335528 | J:160481
First Author: Coffey F
Year: 2010
Journal: J Immunol
Title: Expression of cellular FLIP by B cells is required for their participation in an immune response.
Volume: 184
Issue: 9
Pages: 4871-9
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20724542 | J:167430
First Author: Huang QQ
Year: 2010
Journal: Blood
Title: FLIP: a novel regulator of macrophage differentiation and granulocyte homeostasis.
Volume: 116
Issue: 23
Pages: 4968-77
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Publication
24270411 | J:229062
First Author: Wu YH
Year: 2014
Journal: Cell Death Differ
Title: Participation of c-FLIP in NLRP3 and AIM2 inflammasome activation.
Volume: 21
Issue: 3
Pages: 451-61
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Publication
20980680 | J:168403
First Author: Gordy C
Year: 2011
Journal: Blood
Title: Regulation of steady-state neutrophil homeostasis by macrophages.
Volume: 117
Issue: 2
Pages: 618-29
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Publication
37813881 | J:341716
First Author: Tsuchiya Y
Year: 2023
Journal: Nat Commun
Title: Fibroblast growth factor 18 stimulates the proliferation of hepatic stellate cells, thereby inducing liver fibrosis.
Volume: 14
Issue: 1
Pages: 6304
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Publication
19429865 | J:151173
First Author: Yu Y
Year: 2009
Journal: Blood
Title: Abundant c-Fas-associated death domain-like interleukin-1-converting enzyme inhibitory protein expression determines resistance of T helper 17 cells to activation-induced cell death.
Volume: 114
Issue: 5
Pages: 1026-8
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Publication
19300454 | J:164184
First Author: Huo J
Year: 2009
Journal: Cell Death Differ
Title: Genetic deletion of faim reveals its role in modulating c-FLIP expression during CD95-mediated apoptosis of lymphocytes and hepatocytes.
Volume: 16
Issue: 7
Pages: 1062-70
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Publication
21435442 | J:169857
First Author: Llobet D
Year: 2011
Journal: Am J Pathol
Title: KSR1 is overexpressed in endometrial carcinoma and regulates proliferation and TRAIL-induced apoptosis by modulating FLIP levels.
Volume: 178
Issue: 4
Pages: 1529-43
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Publication
18832693 | J:140768
First Author: Zhang N
Year: 2008
Journal: J Immunol
Title: c-FLIP protects mature T lymphocytes from TCR-mediated killing.
Volume: 181
Issue: 8
Pages: 5368-73
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Publication
17581950 | J:122799
First Author: Taoufik E
Year: 2007
Journal: J Neurosci
Title: FLIP(L) protects neurons against in vivo ischemia and in vitro glucose deprivation-induced cell death.
Volume: 27
Issue: 25
Pages: 6633-46
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Publication
18390734 | J:134252
First Author: Zhang N
Year: 2008
Journal: J Immunol
Title: The long isoform of cellular FLIP is essential for T lymphocyte proliferation through an NF-kappaB-independent pathway.
Volume: 180
Issue: 8
Pages: 5506-11
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Publication
37216119 | J:338924
First Author: Huang QQ
Year: 2023
Journal: iScience
Title: Mechanisms regulating the loss of Tregs in HUPO mice that develop spontaneous inflammatory arthritis.
Volume: 26
Issue: 5
Pages: 106734
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Publication
28052242 | J:251487
First Author: Plaza-Sirvent C
Year: 2017
Journal: Cell Rep
Title: c-FLIP Expression in Foxp3-Expressing Cells Is Essential for Survival of Regulatory T Cells and Prevention of Autoimmunity.
Volume: 18
Issue: 1
Pages: 12-22
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Publication
22406316 | J:183243
First Author: Schattenberg JM
Year: 2012
Journal: Free Radic Biol Med
Title: The role of death effector domain-containing proteins in acute oxidative cell injury in hepatocytes.
Volume: 52
Issue: 9
Pages: 1911-7
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Publication
19587217 | J:152093
First Author: Vesely ED
Year: 2009
Journal: Am J Physiol Cell Physiol
Title: GLUT1-induced cFLIP expression promotes proliferation and prevents apoptosis in vascular smooth muscle cells.
Volume: 297
Issue: 3
Pages: C759-65
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Publication
19373244 | J:164180
First Author: Zhu JY
Year: 2009
Journal: Cell Death Differ
Title: Rocaglamide sensitizes leukemic T cells to activation-induced cell death by differential regulation of CD95L and c-FLIP expression.
Volume: 16
Issue: 9
Pages: 1289-99
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22095280 | J:203612
First Author: Moujalled DM
Year: 2012
Journal: Cell Death Differ
Title: In mouse embryonic fibroblasts, neither caspase-8 nor cellular FLICE-inhibitory protein (FLIP) is necessary for TNF to activate NF-κB, but caspase-8 is required for TNF to cause cell death, and induction of FLIP by NF-κB is required to prevent it.
Volume: 19
Issue: 5
Pages: 808-15
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10894163 | J:63049
First Author: Yeh WC
Year: 2000
Journal: Immunity
Title: Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development.
Volume: 12
Issue: 6
Pages: 633-42
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12244156 | J:79241
First Author: Chastagner P
Year: 2002
Journal: J Immunol
Title: Lymphoadenopathy in IL-2-deficient mice: further characterization and overexpression of the antiapoptotic molecule cellular FLIP.
Volume: 169
Issue: 7
Pages: 3644-51
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24036366 | J:283854
First Author: Wittkopf N
Year: 2013
Journal: Gastroenterology
Title: Cellular FLICE-like inhibitory protein secures intestinal epithelial cell survival and immune homeostasis by regulating caspase-8.
Volume: 145
Issue: 6
Pages: 1369-79
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Publication
33238518 | J:304995
 
First Author: Feoktistova M
Year: 2020
Journal: Int J Mol Sci
Title: TNF Is Partially Required for Cell-Death-Triggered Skin Inflammation upon Acute Loss of cFLIP.
Volume: 21
Issue: 22
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25963626 | J:224881
 
First Author: Huang QQ
Year: 2015
Journal: Nat Commun
Title: CD11c-mediated deletion of Flip promotes autoreactivity and inflammatory arthritis.
Volume: 6
Pages: 7086
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9729047 | J:49459
First Author: Varfolomeev EE
Year: 1998
Journal: Immunity
Title: Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.
Volume: 9
Issue: 2
Pages: 267-76
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15972663 | J:100574
First Author: Dohrman A
Year: 2005
Journal: J Immunol
Title: Cellular FLIP long form augments caspase activity and death of T cells through heterodimerization with and activation of caspase-8.
Volume: 175
Issue: 1
Pages: 311-8
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27523270 | J:254600
First Author: Alvarez-Diaz S
Year: 2016
Journal: Immunity
Title: The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis.
Volume: 45
Issue: 3
Pages: 513-526
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11247636 | J:68151
First Author: Bergman ML
Year: 2001
Journal: J Autoimmun
Title: CTLA-4-/- mice display T cell-apoptosis resistance resembling that ascribed to autoimmune-prone non-obese diabetic (NOD) mice.
Volume: 16
Issue: 2
Pages: 105-13
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16783640 | J:110034
First Author: Behnke JM
Year: 2006
Journal: Mamm Genome
Title: High resolution mapping of chromosomal regions controlling resistance to gastrointestinal nematode infections in an advanced intercross line of mice.
Volume: 17
Issue: 6
Pages: 584-97
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23424201 | J:200588
First Author: Ye J
Year: 2013
Journal: J Cell Sci
Title: A pathway involving HDAC5, cFLIP and caspases regulates expression of the splicing regulator polypyrimidine tract binding protein in the heart.
Volume: 126
Issue: Pt 7
Pages: 1682-91
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16263940 | J:104561
First Author: Giampietri C
Year: 2006
Journal: FASEB J
Title: c-Flip expression and function in fetal mouse gonocytes.
Volume: 20
Issue: 1
Pages: 124-6
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21803845 | J:184109
First Author: Tao RH
Year: 2011
Journal: Blood
Title: PMLRARα binds to Fas and suppresses Fas-mediated apoptosis through recruiting c-FLIP in vivo.
Volume: 118
Issue: 11
Pages: 3107-18
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11544288 | J:71496
First Author: Elzey BD
Year: 2001
Journal: J Immunol
Title: Regulation of Fas ligand-induced apoptosis by TNF.
Volume: 167
Issue: 6
Pages: 3049-56
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20427667 | J:159826
First Author: Moubarak RS
Year: 2010
Journal: J Neurosci
Title: The death receptor antagonist FLIP-L interacts with Trk and is necessary for neurite outgrowth induced by neurotrophins.
Volume: 30
Issue: 17
Pages: 6094-105
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24095739 | J:203778
First Author: Weinlich R
Year: 2013
Journal: Cell Rep
Title: Protective roles for caspase-8 and cFLIP in adult homeostasis.
Volume: 5
Issue: 2
Pages: 340-8
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25500368 | J:279553
First Author: Haverkamp JM
Year: 2014
Journal: Immunity
Title: Myeloid-derived suppressor activity is mediated by monocytic lineages maintained by continuous inhibition of extrinsic and intrinsic death pathways.
Volume: 41
Issue: 6
Pages: 947-59
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22675671 | J:196028
First Author: Dillon CP
Year: 2012
Journal: Cell Rep
Title: Survival function of the FADD-CASPASE-8-cFLIP(L) complex.
Volume: 1
Issue: 5
Pages: 401-7
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21368763 | J:170814
First Author: Oberst A
Year: 2011
Journal: Nature
Title: Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis.
Volume: 471
Issue: 7338
Pages: 363-7
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15282307 | J:92273
First Author: Gilbert S
Year: 2004
Journal: Mol Cell Biol
Title: Keratins modulate c-Flip/extracellular signal-regulated kinase 1 and 2 antiapoptotic signaling in simple epithelial cells.
Volume: 24
Issue: 16
Pages: 7072-81
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24813850 | J:214393
First Author: Dillon CP
Year: 2014
Journal: Cell
Title: RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3.
Volume: 157
Issue: 5
Pages: 1189-202
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27819682 | J:242990
First Author: Newton K
Year: 2016
Journal: Nature
Title: RIPK1 inhibits ZBP1-driven necroptosis during development.
Volume: 540
Issue: 7631
Pages: 129-133
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35296858 | J:326155
First Author: Maudet C
Year: 2022
Journal: Nature
Title: Bacterial inhibition of Fas-mediated killing promotes neuroinvasion and persistence.
Volume: 603
Issue: 7903
Pages: 900-906
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16469705 | J:114810
First Author: Chang L
Year: 2006
Journal: Cell
Title: The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover.
Volume: 124
Issue: 3
Pages: 601-13
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32103006 | J:287252
First Author: Bank U
Year: 2020
Journal: Nat Commun
Title: c-FLIP is crucial for IL-7/IL-15-dependent NKp46+ ILC development and protection from intestinal inflammation in mice.
Volume: 11
Issue: 1
Pages: 1056
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18708583 | J:138979
First Author: Schile AJ
Year: 2008
Journal: Genes Dev
Title: Regulation of apoptosis by XIAP ubiquitin-ligase activity.
Volume: 22
Issue: 16
Pages: 2256-66
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32193329 | J:286605
First Author: Muendlein HI
Year: 2020
Journal: Science
Title: cFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation.
Volume: 367
Issue: 6484
Pages: 1379-1384
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22089168 | J:202809
 
First Author: Vanlangenakker N
Year: 2011
Journal: Cell Death Dis
Title: TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members.
Volume: 2
Pages: e230
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17462996 | J:123526
First Author: Misra RS
Year: 2007
Journal: J Biol Chem
Title: Caspase-8 and c-FLIPL associate in lipid rafts with NF-kappaB adaptors during T cell activation.
Volume: 282
Issue: 27
Pages: 19365-74
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24275659 | J:319042
First Author: Koenig A
Year: 2014
Journal: J Biol Chem
Title: The c-FLIPL cleavage product p43FLIP promotes activation of extracellular signal-regulated kinase (ERK), nuclear factor κB (NF-κB), and caspase-8 and T cell survival.
Volume: 289
Issue: 2
Pages: 1183-91
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31511692 | J:281456
First Author: Newton K
Year: 2019
Journal: Nature
Title: Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis.
Volume: 574
Issue: 7778
Pages: 428-431
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23144495 | J:190865
First Author: Bossaller L
Year: 2012
Journal: J Immunol
Title: Cutting edge: FAS (CD95) mediates noncanonical IL-1β and IL-18 maturation via caspase-8 in an RIP3-independent manner.
Volume: 189
Issue: 12
Pages: 5508-12
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31723262 | J:285940
First Author: Newton K
Year: 2019
Journal: Nature
Title: Activity of caspase-8 determines plasticity between cell death pathways.
Volume: 575
Issue: 7784
Pages: 679-682
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17488888 | J:127224
First Author: Prows DR
Year: 2007
Journal: Physiol Genomics
Title: Genetic analysis of hyperoxic acute lung injury survival in reciprocal intercross mice.
Volume: 30
Issue: 3
Pages: 271-81
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26582200 | J:230059
First Author: Urresti J
Year: 2016
Journal: J Biol Chem
Title: Lifeguard Inhibits Fas Ligand-mediated Endoplasmic Reticulum-Calcium Release Mandatory for Apoptosis in Type II Apoptotic Cells.
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