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Search results 1 to 100 out of 1246 for Col2a1

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Type Details Score
Publication
9264261 | J:54915
First Author: Zhao Q
Year: 1997
Journal: Dev Dyn
Title: Parallel expression of Sox9 and Col2a1 in cells undergoing chondrogenesis.
Volume: 209
Issue: 4
Pages: 377-86
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Publication
22028304 | J:187141
First Author: Esapa CT
Year: 2012
Journal: J Bone Miner Res
Title: A mouse model for spondyloepiphyseal dysplasia congenita with secondary osteoarthritis due to a Col2a1 mutation.
Volume: 27
Issue: 2
Pages: 413-28
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Publication
14614991 | J:87774
First Author: Fernandes RJ
Year: 2003
Journal: Matrix Biol
Title: Protein consequences of the Col2a1 C-propeptide mutation in the chondrodysplastic Dmm mouse.
Volume: 22
Issue: 5
Pages: 449-53
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Publication
12968670 | J:85735
First Author: Donahue LR
Year: 2003
Journal: J Bone Miner Res
Title: A missense mutation in the mouse Col2a1 gene causes spondyloepiphyseal dysplasia congenita, hearing loss, and retinoschisis.
Volume: 18
Issue: 9
Pages: 1612-21
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Publication
19014360 | J:306544
First Author: Hyde G
Year: 2008
Journal: J Anat
Title: Col2a1 lineage tracing reveals that the meniscus of the knee joint has a complex cellular origin.
Volume: 213
Issue: 5
Pages: 531-8
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Publication
15476249 | J:134147
First Author: Sahlman J
Year: 2004
Journal: Arthritis Rheum
Title: A human COL2A1 gene with an Arg519Cys mutation causes osteochondrodysplasia in transgenic mice.
Volume: 50
Issue: 10
Pages: 3153-60
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Publication
24168833 | J:294744
First Author: Yang RC
Year: 2014
Journal: J Formos Med Assoc
Title: A mutation of the Col2a1 gene (G1170S) alters the transgenic murine phenotype and cartilage matrix homeostasis.
Volume: 113
Issue: 11
Pages: 803-12
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Publication
24475193 | J:212712
First Author: Liang G
Year: 2014
Journal: PLoS One
Title: Endoplasmic reticulum stress-unfolding protein response-apoptosis cascade causes chondrodysplasia in a col2a1 p.Gly1170Ser mutated mouse model.
Volume: 9
Issue: 1
Pages: e86894
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Publication
22248926 | J:184499
First Author: Lewis R
Year: 2012
Journal: Matrix Biol
Title: Disruption of the developmentally-regulated Col2a1 pre-mRNA alternative splicing switch in a transgenic knock-in mouse model.
Volume: 31
Issue: 3
Pages: 214-26
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Publication
10620515 | J:60148
 
First Author: Yuan CM
Year: 2000
Journal: Biochem J
Title: Lack of a phenotype in transgenic mice aberrantly expressing COL2A1 mRNA because of highly selective post-transcriptional down-regulation.
Volume: 345 Pt 2
Pages: 377-84
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Publication
9915573 | J:51968
First Author: Rani PU
Year: 1999
Journal: Dev Dyn
Title: Restoration of normal bone development by human homologue of collagen type II (COL2A1) gene in Col2a1 null mice.
Volume: 214
Issue: 1
Pages: 26-33
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Publication
- | J:187363
     
First Author: Curtain MM
Year: 2012
Journal: MGI Direct Data Submission
Title: A New Point Mutation in Col2a1 Causes a Shortened Nose and Cleft Palate
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Publication
10100048 | J:54161
First Author: Maddox BK
Year: 1998
Journal: J Craniofac Genet Dev Biol
Title: Craniofacial and otic capsule abnormalities in a transgenic mouse strain with a Col2a1 mutation.
Volume: 18
Issue: 4
Pages: 195-201
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Publication
12917109 | J:87136
First Author: Barbieri O
Year: 2003
Journal: Am J Physiol Cell Physiol
Title: Depletion of cartilage collagen fibrils in mice carrying a dominant negative Col2a1 transgene affects chondrocyte differentiation.
Volume: 285
Issue: 6
Pages: C1504-12
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Publication
26545783 | J:260538
First Author: Kimura M
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Endoplasmic reticulum stress-mediated apoptosis contributes to a skeletal dysplasia resembling platyspondylic lethal skeletal dysplasia, Torrance type, in a novel Col2a1 mutant mouse line.
Volume: 468
Issue: 1-2
Pages: 86-91
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Publication
9614106 | J:48126
First Author: Zhou G
Year: 1998
Journal: J Biol Chem
Title: Three high mobility group-like sequences within a 48-base pair enhancer of the Col2a1 gene are required for cartilage-specific expression in vivo.
Volume: 273
Issue: 24
Pages: 14989-97
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Publication
21538020 | J:171906
First Author: Furuichi T
Year: 2011
Journal: Mamm Genome
Title: ENU-induced missense mutation in the C-propeptide coding region of Col2a1 creates a mouse model of platyspondylic lethal skeletal dysplasia, Torrance type.
Volume: 22
Issue: 5-6
Pages: 318-28
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Publication
24735995 | J:215404
 
First Author: Hering TM
Year: 2014
Journal: Matrix Biol
Title: Changes in type II procollagen isoform expression during chondrogenesis by disruption of an alternative 5' splice site within Col2a1 exon 2.
Volume: 36
Pages: 51-63
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Publication
9061443 | J:39102
 
First Author: Rintala M
Year: 1997
Journal: J Anat
Title: Abnormal craniofacial growth and early mandibular osteoarthritis in mice harbouring a mutant type II collagen transgene.
Volume: 190 ( Pt 2)
Pages: 201-8
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Publication
9171829 | J:41294
First Author: Bell DM
Year: 1997
Journal: Nat Genet
Title: SOX9 directly regulates the type-II collagen gene.
Volume: 16
Issue: 2
Pages: 174-8
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Publication
8349798 | J:14164
First Author: Helminen HJ
Year: 1993
Journal: J Clin Invest
Title: An inbred line of transgenic mice expressing an internally deleted gene for type II procollagen (COL2A1). Young mice have a variable phenotype of a chondrodysplasia and older mice have osteoarthritic changes in joints.
Volume: 92
Issue: 2
Pages: 582-95
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Publication
12359167 | J:307985
First Author: Arita M
Year: 2002
Journal: Osteoarthritis Cartilage
Title: Skeletal abnormalities and ultrastructural changes of cartilage in transgenic mice expressing a collagen II gene (COL2A1) with a Cys for Arg-alpha1-519 substitution.
Volume: 10
Issue: 10
Pages: 808-15
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Publication
22547066 | J:187536
First Author: Yamashita S
Year: 2012
Journal: J Biol Chem
Title: L-Sox5 and Sox6 proteins enhance chondrogenic miR-140 microRNA expression by strengthening dimeric Sox9 activity.
Volume: 287
Issue: 26
Pages: 22206-15
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Publication
26058470 | J:309481
First Author: Park NR
Year: 2016
Journal: J Cell Physiol
Title: Core Binding Factor β Plays a Critical Role During Chondrocyte Differentiation.
Volume: 231
Issue: 1
Pages: 162-71
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24862038 | J:310847
First Author: Chen H
Year: 2014
Journal: J Bone Miner Res
Title: Runx2 regulates endochondral ossification through control of chondrocyte proliferation and differentiation.
Volume: 29
Issue: 12
Pages: 2653-65
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Publication
1492704 | J:3718
First Author: Imam-Ghali M
Year: 1992
Journal: Anim Genet
Title: Sheep gene mapping: synteny between COL2A1 and the LDHB-PEPB-TPI-GAPD-LALBA-IGF1 group.
Volume: 23
Issue: 6
Pages: 529-32
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Publication
23555635 | J:199887
First Author: Tomita N
Year: 2013
Journal: PLoS One
Title: Cartilage-specific over-expression of CCN family member 2/connective tissue growth factor (CCN2/CTGF) stimulates insulin-like growth factor expression and bone growth.
Volume: 8
Issue: 3
Pages: e59226
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28167493 | J:241785
First Author: Whitaker AT
Year: 2017
Journal: Biol Open
Title: Smad4 regulates growth plate matrix production and chondrocyte polarity.
Volume: 6
Issue: 3
Pages: 358-364
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Publication
25600960 | J:231358
First Author: Cameron TL
Year: 2015
Journal: Osteoarthritis Cartilage
Title: Cartilage-specific ablation of XBP1 signaling in mouse results in a chondrodysplasia characterized by reduced chondrocyte proliferation and delayed cartilage maturation and mineralization.
Volume: 23
Issue: 4
Pages: 661-70
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Publication
1881905 | J:31511
First Author: Vandenberg P
Year: 1991
Journal: Proc Natl Acad Sci U S A
Title: Expression of a partially deleted gene of human type II procollagen (COL2A1) in transgenic mice produces a chondrodysplasia.
Volume: 88
Issue: 17
Pages: 7640-4
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1618904 | J:1279
First Author: Metsäranta M
Year: 1992
Journal: J Cell Biol
Title: Chondrodysplasia in transgenic mice harboring a 15-amino acid deletion in the triple helical domain of pro alpha 1(II) collagen chain.
Volume: 118
Issue: 1
Pages: 203-12
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7994081 | J:19890
First Author: Hiltunen A
Year: 1994
Journal: Dev Dyn
Title: Retarded chondrogenesis in transgenic mice with a type II collagen defect results in fracture healing abnormalities.
Volume: 200
Issue: 4
Pages: 340-9
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8872705 | J:35591
First Author: Rintala M
Year: 1996
Journal: J Craniofac Genet Dev Biol
Title: Abnormalities in secondary cartilages in four lines of transgenic mice harboring two different types of mutations in the cartilage-specific type II collagen gene.
Volume: 16
Issue: 3
Pages: 148-55
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12525971 | J:80671
First Author: Ihanamäki T
Year: 2002
Journal: Curr Eye Res
Title: Ultrastructural characterization of developmental and degenerative vitreo-retinal changes in the eyes of transgenic mice with a deletion mutation in type II collagen gene.
Volume: 24
Issue: 6
Pages: 439-50
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11273670 | J:68440
First Author: Ihanamäki T
Year: 2001
Journal: Exp Eye Res
Title: Age-dependent changes in the expression of matrix components in the mouse eye.
Volume: 72
Issue: 4
Pages: 423-31
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Publication
- | J:148829
     
First Author: Esapa C
Year: 2009
Journal: MGI Direct Data Submission
Title: Lpk, longpockets, is an ENU induced mutation and results in a short-limbed phenotype: Record for "Lpk"
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Publication
29287114 | J:256718
First Author: Shimbo M
Year: 2017
Journal: PLoS One
Title: Postnatal lethality and chondrodysplasia in mice lacking both chondroitin sulfate N-acetylgalactosaminyltransferase-1 and -2.
Volume: 12
Issue: 12
Pages: e0190333
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Publication
37159303 | J:344106
First Author: Ding W
Year: 2023
Journal: FASEB J
Title: Hu'po Anshen decoction promotes fracture healing in mice with traumatic brain injury through BMP2-COX2-ATF4 signaling pathway.
Volume: 37
Issue: 6
Pages: e22952
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17519362 | J:127222
First Author: Govoni KE
Year: 2007
Journal: Physiol Genomics
Title: Disruption of insulin-like growth factor-I expression in type IIalphaI collagen-expressing cells reduces bone length and width in mice.
Volume: 30
Issue: 3
Pages: 354-62
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Publication
12510713 | J:81856
First Author: Ihanamäki T
Year: 2002
Journal: Eur J Ophthalmol
Title: Expression of Sox9 and type IIA procollagen during ocular development and aging in transgenic Del1 mice with a mutation in the type II collagen gene.
Volume: 12
Issue: 6
Pages: 450-8
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Publication
15562585 | J:95068
First Author: Savontaus M
Year: 2004
Journal: Orthod Craniofac Res
Title: Abnormal craniofacial development and expression patterns of extracellular matrix components in transgenic Del1 mice harboring a deletion mutation in the type II collagen gene.
Volume: 7
Issue: 4
Pages: 216-26
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Publication
22492985 | J:197791
First Author: Masago Y
Year: 2012
Journal: J Cell Sci
Title: The molecular chaperone Hsp47 is essential for cartilage and endochondral bone formation.
Volume: 125
Issue: Pt 5
Pages: 1118-28
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9426396 | J:44842
First Author: Savontaus M
Year: 1997
Journal: Lab Invest
Title: Mutation in type II collagen gene disturbs spinal development and gene expression patterns in transgenic Del1 mice.
Volume: 77
Issue: 6
Pages: 591-600
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Publication
15531369 | J:95024
First Author: Baffi MO
Year: 2004
Journal: Dev Biol
Title: Conditional deletion of the TGF-beta type II receptor in Col2a expressing cells results in defects in the axial skeleton without alterations in chondrocyte differentiation or embryonic development of long bones.
Volume: 276
Issue: 1
Pages: 124-42
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8952549 | J:37148
First Author: Savontaus M
Year: 1996
Journal: Am J Pathol
Title: Retarded skeletal development in transgenic mice with a type II collagen mutation.
Volume: 149
Issue: 6
Pages: 2169-82
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7590256 | J:30041
First Author: Li SW
Year: 1995
Journal: Genes Dev
Title: Transgenic mice with targeted inactivation of the Col2 alpha 1 gene for collagen II develop a skeleton with membranous and periosteal bone but no endochondral bone.
Volume: 9
Issue: 22
Pages: 2821-30
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Publication
25541700 | J:225386
First Author: Cionni M
Year: 2014
Journal: PLoS One
Title: The mouse MC13 mutant is a novel ENU mutation in collagen type II, alpha 1.
Volume: 9
Issue: 12
Pages: e116104
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8948452 | J:26245
 
First Author: Ala-Kokko L
Year: 1995
Journal: Biochem J
Title: Conservation of the sizes of 53 introns and over 100 intronic sequences for the binding of common transcription factors in the human and mouse genes for type II procollagen (COL2A1).
Volume: 308 ( Pt 3)
Pages: 923-9
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Publication
38844479 | J:349720
First Author: Darbellay F
Year: 2024
Journal: Nat Commun
Title: Pre-hypertrophic chondrogenic enhancer landscape of limb and axial skeleton development.
Volume: 15
Issue: 1
Pages: 4820
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Publication
21246657 | J:167831
First Author: Moffatt P
Year: 2011
Journal: Dev Dyn
Title: Hyaluronan production by means of Has2 gene expression in chondrocytes is essential for long bone development.
Volume: 240
Issue: 2
Pages: 404-12
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Publication
15509771 | J:94393
First Author: Karreth F
Year: 2004
Journal: Development
Title: The AP1 transcription factor Fra2 is required for efficient cartilage development.
Volume: 131
Issue: 22
Pages: 5717-25
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18025304 | J:135374
First Author: Patra D
Year: 2007
Journal: J Cell Biol
Title: Site-1 protease is essential for endochondral bone formation in mice.
Volume: 179
Issue: 4
Pages: 687-700
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21420501 | J:172689
First Author: Wang M
Year: 2011
Journal: Osteoarthritis Cartilage
Title: Smad1 plays an essential role in bone development and postnatal bone formation.
Volume: 19
Issue: 6
Pages: 751-62
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Publication
22290230 | J:181485
First Author: Oh JH
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Chondrocyte-specific ablation of Osterix leads to impaired endochondral ossification.
Volume: 418
Issue: 4
Pages: 634-40
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18678883 | J:142158
First Author: Seegmiller RE
Year: 2008
Journal: J Histochem Cytochem
Title: The heterozygous disproportionate micromelia (dmm) mouse: morphological changes in fetal cartilage precede postnatal dwarfism and compared with lethal homozygotes can explain the mild phenotype.
Volume: 56
Issue: 11
Pages: 1003-11
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31958497 | J:307328
First Author: Rolvien T
Year: 2020
Journal: Osteoarthritis Cartilage
Title: Skeletal deterioration in COL2A1-related spondyloepiphyseal dysplasia occurs prior to osteoarthritis.
Volume: 28
Issue: 3
Pages: 334-343
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9022054 | J:38204
First Author: Maddox BK
Year: 1997
Journal: Dev Dyn
Title: Skeletal development in transgenic mice expressing a mutation at Gly574Ser of type II collagen.
Volume: 208
Issue: 2
Pages: 170-7
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1637314 | J:1390
 
First Author: Vikkula M
Year: 1992
Journal: Biochem J
Title: Structural analysis of the regulatory elements of the type-II procollagen gene. Conservation of promoter and first intron sequences between human and mouse.
Volume: 285 ( Pt 1)
Pages: 287-94
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17652426 | J:128720
First Author: Imai K
Year: 2007
Journal: Am J Physiol Cell Physiol
Title: Bone growth retardation in mouse embryos expressing human collagenase 1.
Volume: 293
Issue: 4
Pages: C1209-15
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23274346 | J:193842
First Author: Lu C
Year: 2013
Journal: Bone
Title: Wnt-mediated reciprocal regulation between cartilage and bone development during endochondral ossification.
Volume: 53
Issue: 2
Pages: 566-74
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17967876 | J:128917
First Author: Provot S
Year: 2008
Journal: Mol Cell Biol
Title: A-raf and B-raf are dispensable for normal endochondral bone development, and parathyroid hormone-related peptide suppresses extracellular signal-regulated kinase activation in hypertrophic chondrocytes.
Volume: 28
Issue: 1
Pages: 344-57
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33879790 | J:307236
First Author: Li Y
Year: 2021
Journal: Cell Discov
Title: TAZ is required for chondrogenesis and skeletal development.
Volume: 7
Issue: 1
Pages: 26
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9755172 | J:50394
First Author: Lefebvre V
Year: 1998
Journal: EMBO J
Title: A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene.
Volume: 17
Issue: 19
Pages: 5718-33
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24218567 | J:202964
First Author: Lai LP
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Lkb1/Stk11 regulation of mTOR signaling controls the transition of chondrocyte fates and suppresses skeletal tumor formation.
Volume: 110
Issue: 48
Pages: 19450-5
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10686612 | J:69318
First Author: Ovchinnikov DA
Year: 2000
Journal: Genesis
Title: Col2a1-directed expression of Cre recombinase in differentiating chondrocytes in transgenic mice.
Volume: 26
Issue: 2
Pages: 145-6
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25451152 | J:216945
First Author: Arita M
Year: 2015
Journal: Am J Pathol
Title: Mechanisms of aberrant organization of growth plates in conditional transgenic mouse model of spondyloepiphyseal dysplasia associated with the R992C substitution in collagen II.
Volume: 185
Issue: 1
Pages: 214-29
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29660427 | J:266654
 
First Author: Fertala J
Year: 2018
Journal: Bone
Title: Epiphyseal growth plate architecture is unaffected by early postnatal activation of the expression of R992C collagen II mutant.
Volume: 112
Pages: 42-50
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22761446 | J:190241
First Author: Itoh S
Year: 2012
Journal: J Biol Chem
Title: GSK-3α and GSK-3β proteins are involved in early stages of chondrocyte differentiation with functional redundancy through RelA protein phosphorylation.
Volume: 287
Issue: 35
Pages: 29227-36
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11171689 | J:106329
First Author: Hyttinen MM
Year: 2001
Journal: Ann Rheum Dis
Title: Inactivation of one allele of the type II collagen gene alters the collagen network in murine articular cartilage and makes cartilage softer.
Volume: 60
Issue: 3
Pages: 262-8
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Publication
11237662 | J:115506
First Author: Lapveteläinen T
Year: 2001
Journal: Osteoarthritis Cartilage
Title: More knee joint osteoarthritis (OA) in mice after inactivation of one allele of type II procollagen gene but less OA after lifelong voluntary wheel running exercise.
Volume: 9
Issue: 2
Pages: 152-60
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37244931 | J:336186
First Author: Sunadome K
Year: 2023
Journal: Nat Commun
Title: Directionality of developing skeletal muscles is set by mechanical forces.
Volume: 14
Issue: 1
Pages: 3060
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Publication
16546167 | J:144313
First Author: Kaarniranta K
Year: 2006
Journal: Exp Eye Res
Title: A mouse model for Stickler's syndrome: ocular phenotype of mice carrying a targeted heterozygous inactivation of type II (pro)collagen gene (Col2a1).
Volume: 83
Issue: 2
Pages: 297-303
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8719874 | J:30169
 
First Author: Zhou G
Year: 1995
Journal: J Cell Sci
Title: A 182 bp fragment of the mouse pro alpha 1(II) collagen gene is sufficient to direct chondrocyte expression in transgenic mice.
Volume: 108 ( Pt 12)
Pages: 3677-84
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19877062 | J:215444
First Author: Kan A
Year: 2009
Journal: Arthritis Rheum
Title: Screening of chondrogenic factors with a real-time fluorescence-monitoring cell line ATDC5-C2ER: identification of sorting nexin 19 as a novel factor.
Volume: 60
Issue: 11
Pages: 3314-23
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8754852 | J:34384
First Author: Lefebvre V
Year: 1996
Journal: Mol Cell Biol
Title: An 18-base-pair sequence in the mouse proalpha1(II) collagen gene is sufficient for expression in cartilage and binds nuclear proteins that are selectively expressed in chondrocytes.
Volume: 16
Issue: 8
Pages: 4512-23
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Publication
24113490 | J:209467
 
First Author: McAlinden A
Year: 2014
Journal: Matrix Biol
Title: Molecular properties and fibril ultrastructure of types II and XI collagens in cartilage of mice expressing exclusively the α1(IIA) collagen isoform.
Volume: 34
Pages: 105-13
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12538525 | J:81355
First Author: Yang Y
Year: 2003
Journal: Development
Title: Wnt5a and Wnt5b exhibit distinct activities in coordinating chondrocyte proliferation and differentiation.
Volume: 130
Issue: 5
Pages: 1003-15
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9119111 | J:38926
First Author: Ng LJ
Year: 1997
Journal: Dev Biol
Title: SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse.
Volume: 183
Issue: 1
Pages: 108-21
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Publication
16905550 | J:117178
First Author: Schmidl M
Year: 2006
Journal: J Biol Chem
Title: Twisted gastrulation modulates bone morphogenetic protein-induced collagen II and X expression in chondrocytes in vitro and in vivo.
Volume: 281
Issue: 42
Pages: 31790-800
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Publication
10825206 | J:62593
First Author: Tanaka K
Year: 2000
Journal: Mol Cell Biol
Title: A zinc finger transcription factor, alphaA-crystallin binding protein 1, is a negative regulator of the chondrocyte-specific enhancer of the alpha1(II) collagen gene.
Volume: 20
Issue: 12
Pages: 4428-35
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Publication
10861287 | J:63198
First Author: Iwata T
Year: 2000
Journal: Hum Mol Genet
Title: A neonatal lethal mutation in FGFR3 uncouples proliferation and differentiation of growth plate chondrocytes in embryos.
Volume: 9
Issue: 11
Pages: 1603-13
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Publication
24269712 | J:207837
 
First Author: Schmid R
Year: 2014
Journal: Mech Dev
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