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Search results 1 to 100 out of 189 for Cyp17a1

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Category: Publication
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Type Details Score
Publication
22266943 | -
First Author: DeVore NM
Year: 2012
Journal: Nature
Title: Structures of cytochrome P450 17A1 with prostate cancer drugs abiraterone and TOK-001.
Volume: 482
Issue: 7383
Pages: 116-9
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Publication
2808364 | -
First Author: Yanase T
Year: 1989
Journal: J Biol Chem
Title: Deletion of a phenylalanine in the N-terminal region of human cytochrome P-450(17 alpha) results in partial combined 17 alpha-hydroxylase/17,20-lyase deficiency.
Volume: 264
Issue: 30
Pages: 18076-82
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Publication
1515452 | -
First Author: Yanase T
Year: 1992
Journal: Biochim Biophys Acta
Title: Molecular basis of apparent isolated 17,20-lyase deficiency: compound heterozygous mutations in the C-terminal region (Arg(496)----Cys, Gln(461)----Stop) actually cause combined 17 alpha-hydroxylase/17,20-lyase deficiency.
Volume: 1139
Issue: 4
Pages: 275-9
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Publication
26819663 | J:354408
First Author: Huang A
Year: 2016
Journal: ACS Med Chem Lett
Title: Discovery of the Selective CYP17A1 Lyase Inhibitor BMS-351 for the Treatment of Prostate Cancer.
Volume: 7
Issue: 1
Pages: 40-5
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Publication
32472014 | J:292099
First Author: Aherrahrou R
Year: 2020
Journal: Sci Rep
Title: CYP17A1 deficient XY mice display susceptibility to atherosclerosis, altered lipidomic profile and atypical sex development.
Volume: 10
Issue: 1
Pages: 8792
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Publication
21123943 | J:171856
First Author: Anakk S
Year: 2011
Journal: J Clin Invest
Title: Combined deletion of Fxr and Shp in mice induces Cyp17a1 and results in juvenile onset cholestasis.
Volume: 121
Issue: 1
Pages: 86-95
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Publication
33033216 | J:356601
First Author: M Real F
Year: 2020
Journal: Science
Title: The mole genome reveals regulatory rearrangements associated with adaptive intersexuality.
Volume: 370
Issue: 6513
Pages: 208-214
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Publication
36640554 | J:338155
 
First Author: Lee SG
Year: 2023
Journal: J Inorg Biochem
Title: Hydroxylation and lyase reactions of steroids catalyzed by mouse cytochrome P450 17A1 (Cyp17a1).
Volume: 240
Pages: 112085
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Publication
27339169 | J:320229
First Author: Wang F
Year: 2016
Journal: Cancer Prev Res (Phila)
Title: Transcriptome Analysis of WHV/c-myc Transgenic Mice Implicates Cytochrome P450 Enzyme 17A1 as a Promising Biomarker for Hepatocellular Carcinoma.
Volume: 9
Issue: 9
Pages: 739-49
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Publication
28036337 | J:251156
First Author: Wen Q
Year: 2016
Journal: PLoS One
Title: Sertoli Cell Wt1 Regulates Peritubular Myoid Cell and Fetal Leydig Cell Differentiation during Fetal Testis Development.
Volume: 11
Issue: 12
Pages: e0167920
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Publication
15890676 | J:100434
First Author: Liu Y
Year: 2005
Journal: Mol Endocrinol
Title: Haploinsufficiency of cytochrome P450 17alpha-hydroxylase/17,20 lyase (CYP17) causes infertility in male mice.
Volume: 19
Issue: 9
Pages: 2380-9
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Publication
15169901 | J:91081
First Author: Bair SR
Year: 2004
Journal: Mol Cell Biol
Title: Deletion of the mouse P450c17 gene causes early embryonic lethality.
Volume: 24
Issue: 12
Pages: 5383-90
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Publication
15666818 | J:97494
First Author: Mellon S
Year: 2004
Journal: Endocr Res
Title: Niemann pick type C disease as a model for defects in neurosteroidogenesis.
Volume: 30
Issue: 4
Pages: 727-35
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Publication
19500726 | J:151426
First Author: Liu Y
Year: 2009
Journal: J Steroid Biochem Mol Biol
Title: Dehydroepiandrosterone formation is independent of cytochrome P450 17alpha-hydroxylase/17, 20 lyase activity in the mouse brain.
Volume: 115
Issue: 3-5
Pages: 86-90
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Publication
6090441 | J:354362
First Author: Malaska T
Year: 1984
Journal: J Biol Chem
Title: Luteinizing hormone and cyclic AMP-mediated induction of microsomal cytochrome P-450 enzymes in cultured mouse Leydig cells.
Volume: 259
Issue: 19
Pages: 11654-7
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Publication
1323057 | J:1281
First Author: Youngblood GL
Year: 1992
Journal: Mol Endocrinol
Title: Isolation and characterization of the mouse P450 17 alpha-hydroxylase/C17-20-lyase gene (Cyp17): transcriptional regulation of the gene by cyclic adenosine 3',5'-monophosphate in MA-10 Leydig cells.
Volume: 6
Issue: 6
Pages: 927-34
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Publication
1478654 | J:3552
First Author: Fan YS
Year: 1992
Journal: Genomics
Title: Localization of the human CYP17 gene (cytochrome P450(17 alpha)) to 10q24.3 by fluorescence in situ hybridization and simultaneous chromosome banding.
Volume: 14
Issue: 4
Pages: 1110-1
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Publication
8243812 | J:14679
First Author: Fevold HR
Year: 1993
Journal: Mol Cell Endocrinol
Title: The sequence of the 5'-end of the rat CYP17 gene, the transcription initiation site and a comparison with the homologous genes of other species.
Volume: 95
Issue: 1-2
Pages: 95-100
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Publication
8994191 | J:37584
First Author: Burgos-Trinidad M
Year: 1997
Journal: Mol Endocrinol
Title: Repression of cAMP-induced expression of the mouse P450 17 alpha-hydroxylase/C17-20 lyase gene (Cyp17) by androgens.
Volume: 11
Issue: 1
Pages: 87-96
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Publication
12446594 | J:80504
First Author: Arlt W
Year: 2002
Journal: Endocrinology
Title: Molecular evolution of adrenarche: structural and functional analysis of p450c17 from four primate species.
Volume: 143
Issue: 12
Pages: 4665-72
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Publication
15761033 | J:99229
First Author: Liu Y
Year: 2005
Journal: Mol Endocrinol
Title: Cytochrome P450 17alpha hydroxylase/17,20 lyase (CYP17) function in cholesterol biosynthesis: identification of squalene monooxygenase (epoxidase) activity associated with CYP17 in Leydig cells.
Volume: 19
Issue: 7
Pages: 1918-31
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Publication
1840559 | J:11237
First Author: Youngblood GL
Year: 1991
Journal: Genomics
Title: Isolation, characterization, and chromosomal mapping of mouse P450 17 alpha-hydroxylase/C17-20 lyase.
Volume: 10
Issue: 1
Pages: 270-5
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Publication
8863187 | J:35585
First Author: Gray SA
Year: 1996
Journal: J Mol Endocrinol
Title: Development of cytochrome P450 17 alpha-hydroxylase (P450c17) mRNA and enzyme activity in neonatal ovaries of normal and hypogonadal (hpg) mice.
Volume: 17
Issue: 1
Pages: 55-60
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Publication
10847589 | J:62557
First Author: Compagnone NA
Year: 2000
Journal: Mol Endocrinol
Title: Novel role for the nuclear phosphoprotein SET in transcriptional activation of P450c17 and initiation of neurosteroidogenesis.
Volume: 14
Issue: 6
Pages: 875-88
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Publication
2848682 | J:26017
First Author: Perkins LM
Year: 1988
Journal: Endocrinology
Title: Quantification of P450scc, P450(17) alpha, and iron sulfur protein reductase in Leydig cells and adrenals of inbred strains of mice.
Volume: 123
Issue: 6
Pages: 2675-82
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Publication
7719026 | J:22442
First Author: Ansari HA
Year: 1995
Journal: Mamm Genome
Title: Human chromosome 10 loci map to three different sheep chromosomes.
Volume: 6
Issue: 1
Pages: 46-8
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Publication
7588370 | J:31107
First Author: Keeney DS
Year: 1995
Journal: Endocr Res
Title: Perspectives in steroid hydroxylase gene expression: novel sites of expression during embryonic development.
Volume: 21
Issue: 1-2
Pages: 103-7
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Publication
24899578 | J:213798
First Author: Mendoza-Villarroel RE
Year: 2014
Journal: Biol Reprod
Title: The nuclear receptor NR2F2 activates star expression and steroidogenesis in mouse MA-10 and MLTC-1 Leydig cells.
Volume: 91
Issue: 1
Pages: 26
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Publication
7913464 | J:19302
First Author: Kagawa N
Year: 1994
Journal: J Biol Chem
Title: A cAMP-regulatory sequence (CRS1) of CYP17 is a cellular target for the homeodomain protein Pbx1.
Volume: 269
Issue: 29
Pages: 18716-9
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7628389 | J:28170
First Author: Li X
Year: 1995
Journal: Endocrinology
Title: Tumor necrosis factor-alpha inhibition of 17 alpha-hydroxylase/C17-20 lyase gene (Cyp17) expression.
Volume: 136
Issue: 8
Pages: 3519-26
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Publication
9303351 | J:92839
First Author: Nordqvist K
Year: 1997
Journal: Int J Dev Biol
Title: An mRNA differential display strategy for cloning genes expressed during mouse gonad development.
Volume: 41
Issue: 4
Pages: 627-38
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Publication
11415992 | J:71936
First Author: Burns KH
Year: 2001
Journal: Endocrinology
Title: Analysis of ovarian gene expression in follicle-stimulating hormone beta knockout mice.
Volume: 142
Issue: 7
Pages: 2742-51
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Publication
33127481 | J:304533
 
First Author: Levy I
Year: 2021
Journal: Mol Cell Endocrinol
Title: A phosphodiesterase 11 (Pde11a) knockout mouse expressed functional but reduced Pde11a: Phenotype and impact on adrenocortical function.
Volume: 520
Pages: 111071
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8013361 | J:19505
First Author: Greco TL
Year: 1994
Journal: Endocrinology
Title: Ontogeny of expression of the genes for steroidogenic enzymes P450 side-chain cleavage, 3 beta-hydroxysteroid dehydrogenase, P450 17 alpha-hydroxylase/C17-20 lyase, and P450 aromatase in fetal mouse gonads.
Volume: 135
Issue: 1
Pages: 262-8
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Publication
20530532 | J:173421
First Author: Kim SM
Year: 2010
Journal: Nucleic Acids Res
Title: Regulation of mouse steroidogenesis by WHISTLE and JMJD1C through histone methylation balance.
Volume: 38
Issue: 19
Pages: 6389-403
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Publication
24725081 | J:214680
First Author: Park E
Year: 2014
Journal: Mol Endocrinol
Title: Differential regulation of steroidogenic enzyme genes by TRα signaling in testicular Leydig cells.
Volume: 28
Issue: 6
Pages: 822-33
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Publication
10441736 | J:56826
First Author: Herron BJ
Year: 1999
Journal: Mamm Genome
Title: Scraggly, a new hair loss mutation on mouse chromosome 19.
Volume: 10
Issue: 9
Pages: 864-9
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7479914 | J:35577
First Author: Sadovsky Y
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: Mice deficient in the orphan receptor steroidogenic factor 1 lack adrenal glands and gonads but express P450 side-chain-cleavage enzyme in the placenta and have normal embryonic serum levels of corticosteroids.
Volume: 92
Issue: 24
Pages: 10939-43
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38517962 | J:346442
First Author: Migale R
Year: 2024
Journal: Sci Adv
Title: FOXL2 interaction with different binding partners regulates the dynamics of ovarian development.
Volume: 10
Issue: 12
Pages: eadl0788
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34561233 | J:333014
First Author: Wartenberg P
Year: 2021
Journal: J Neurosci
Title: Sexually Dimorphic Neurosteroid Synthesis Regulates Neuronal Activity in the Murine Brain.
Volume: 41
Issue: 44
Pages: 9177-9191
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7958412 | J:21125
First Author: Lee CH
Year: 1994
Journal: Dev Biol
Title: Normal onset, but prolonged expression, of Sry gene in the B6.YDOM sex-reversed mouse gonad.
Volume: 165
Issue: 2
Pages: 442-52
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Publication
7835908 | J:20828
First Author: Taylor BA
Year: 1994
Journal: Genomics
Title: The retinal outer segment membrane protein-1 gene (Rom1) maps to the proximal end of mouse chromosome 19.
Volume: 23
Issue: 2
Pages: 510-1
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Publication
16003771 | J:100239
First Author: Hinshelwood MM
Year: 2005
Journal: Dev Dyn
Title: Temporal and spatial expression of liver receptor homologue-1 (LRH-1) during embryogenesis suggests a potential role in gonadal development.
Volume: 234
Issue: 1
Pages: 159-68
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17890294 | J:125377
First Author: Hu L
Year: 2007
Journal: Reproduction
Title: Expression of Cyp21a1 and Cyp11b1 in the fetal mouse testis.
Volume: 134
Issue: 4
Pages: 585-91
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24105479 | J:205146
First Author: Praktiknjo SD
Year: 2013
Journal: Endocrinology
Title: Novel effects of chromosome Y on cardiac regulation, chromatin remodeling, and neonatal programming in male mice.
Volume: 154
Issue: 12
Pages: 4746-56
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24694307 | J:214688
First Author: Daems C
Year: 2014
Journal: Mol Endocrinol
Title: MEF2 is restricted to the male gonad and regulates expression of the orphan nuclear receptor NR4A1.
Volume: 28
Issue: 6
Pages: 886-98
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9256466 | J:42484
First Author: Gardner JM
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: The mouse pale ear (ep) mutation is the homologue of human Hermansky-Pudlak syndrome.
Volume: 94
Issue: 17
Pages: 9238-43
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9492048 | J:46691
First Author: O'Shaughnessy PJ
Year: 1998
Journal: Endocrinology
Title: Fetal development of Leydig cell activity in the mouse is independent of pituitary gonadotroph function.
Volume: 139
Issue: 3
Pages: 1141-6
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Publication
11247667 | J:68175
First Author: Rieger DK
Year: 2001
Journal: Genomics
Title: A double-deletion mutation in the Pitx3 gene causes arrested lens development in aphakia mice.
Volume: 72
Issue: 1
Pages: 61-72
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Publication
20454446 | J:160549
First Author: Liu CF
Year: 2010
Journal: PLoS One
Title: WNT4/beta-catenin pathway maintains female germ cell survival by inhibiting activin betaB in the mouse fetal ovary.
Volume: 5
Issue: 4
Pages: e10382
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Publication
12399432 | J:80420
First Author: Heikkilä M
Year: 2002
Journal: Endocrinology
Title: Wnt-4 deficiency alters mouse adrenal cortex function, reducing aldosterone production.
Volume: 143
Issue: 11
Pages: 4358-65
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Publication
15829514 | J:98517
First Author: Park SY
Year: 2005
Journal: Development
Title: Nuclear receptors Sf1 and Dax1 function cooperatively to mediate somatic cell differentiation during testis development.
Volume: 132
Issue: 10
Pages: 2415-23
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10029587 | J:53330
First Author: Morohashi K
Year: 1999
Journal: Blood
Title: Structural and functional abnormalities in the spleen of an mFtz-F1 gene-disrupted mouse.
Volume: 93
Issue: 5
Pages: 1586-94
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Publication
27498191 | J:308132
 
First Author: Alankarage D
Year: 2016
Journal: Int J Biochem Cell Biol
Title: SOX9 regulates expression of the male fertility gene Ets variant factor 5 (ETV5) during mammalian sex development.
Volume: 79
Pages: 41-51
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22116255 | J:290897
First Author: Auguste A
Year: 2011
Journal: Sex Dev
Title: Loss of R-spondin1 and Foxl2 amplifies female-to-male sex reversal in XX mice.
Volume: 5
Issue: 6
Pages: 304-17
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21209421 | J:173724
First Author: Barsoum I
Year: 2011
Journal: Biol Reprod
Title: Redundant and differential roles of transcription factors Gli1 and Gli2 in the development of mouse fetal Leydig cells.
Volume: 84
Issue: 5
Pages: 894-9
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27732090 | J:240774
First Author: Umehara T
Year: 2016
Journal: Endocrinology
Title: Neuregulin 1 Regulates Proliferation of Leydig Cells to Support Spermatogenesis and Sexual Behavior in Adult Mice.
Volume: 157
Issue: 12
Pages: 4899-4913
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Publication
11919667 | J:91457
First Author: Buck KJ
Year: 2002
Journal: Psychopharmacology (Berl)
Title: Mapping murine loci for physical dependence on ethanol.
Volume: 160
Issue: 4
Pages: 398-407
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27734842 | J:251841
 
First Author: York JP
Year: 2016
Journal: Sci Rep
Title: Growth Arrest Specific 2 (GAS2) is a Critical Mediator of Germ Cell Cyst Breakdown and Folliculogenesis in Mice.
Volume: 6
Pages: 34956
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7588219 | J:29760
First Author: Keeney DS
Year: 1995
Journal: Endocrinology
Title: Developmentally regulated expression of adrenal 17 alpha-hydroxylase cytochrome P450 in the mouse embryo.
Volume: 136
Issue: 11
Pages: 4872-9
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8043950 | J:18648
First Author: O'Brien EP
Year: 1994
Journal: Mamm Genome
Title: Molecular map of chromosome 19 including three genes affecting bleeding time: ep, ru, and bm.
Volume: 5
Issue: 6
Pages: 356-60
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9052933 | J:32243
First Author: Strömstedt M
Year: 1996
Journal: Mol Reprod Dev
Title: Preimplantation mouse blastocysts fail to express CYP genes required for estrogen biosynthesis.
Volume: 43
Issue: 4
Pages: 428-36
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16949566 | J:114383
First Author: Val P
Year: 2006
Journal: Dev Biol
Title: Identification of a novel population of adrenal-like cells in the mammalian testis.
Volume: 299
Issue: 1
Pages: 250-6
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Publication
22649409 | J:312043
 
First Author: Galdo M
Year: 2012
Journal: Front Endocrinol (Lausanne)
Title: Dehydroepiandrosterone biosynthesis, role, and mechanism of action in the developing neural tube.
Volume: 3
Pages: 16
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9989404 | J:52554
First Author: Vainio S
Year: 1999
Journal: Nature
Title: Female development in mammals is regulated by Wnt-4 signalling.
Volume: 397
Issue: 6718
Pages: 405-9
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Publication
26470726 | J:258502
First Author: Fouchécourt S
Year: 2016
Journal: Cell Death Differ
Title: Apoptosis of Sertoli cells after conditional ablation of murine double minute 2 (Mdm2) gene is p53-dependent and results in male sterility.
Volume: 23
Issue: 3
Pages: 521-30
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7476982 | J:27992
First Author: Keeney DS
Year: 1995
Journal: Mol Endocrinol
Title: Cholesterol side-chain cleavage cytochrome P450 gene expression in the primitive gut of the mouse embryo does not require steroidogenic factor 1.
Volume: 9
Issue: 8
Pages: 1091-8
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Publication
10436162 | J:56699
First Author: Miyashita-Lin EM
Year: 1999
Journal: Science
Title: Early neocortical regionalization in the absence of thalamic innervation.
Volume: 285
Issue: 5429
Pages: 906-9
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Publication
22294746 | J:183814
First Author: Ludbrook LM
Year: 2012
Journal: Endocrinology
Title: Excess DAX1 leads to XY ovotesticular disorder of sex development (DSD) in mice by inhibiting steroidogenic factor-1 (SF1) activation of the testis enhancer of SRY-box-9 (Sox9).
Volume: 153
Issue: 4
Pages: 1948-58
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7835879 | J:20807
First Author: Keller SA
Year: 1994
Journal: Genomics
Title: Kidney and retinal defects (Krd), a transgene-induced mutation with a deletion of mouse chromosome 19 that includes the Pax2 locus.
Volume: 23
Issue: 2
Pages: 309-20
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Publication
31100714 | J:285721
First Author: Piprek RP
Year: 2019
Journal: Reproduction
Title: Tissue-specific knockout of E-cadherin (Cdh1) in developing mouse gonads causes germ cells loss.
Volume: 158
Issue: 2
Pages: 147-157
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Publication
30793514 | J:308912
First Author: Bergeron F
Year: 2019
Journal: Andrology
Title: Phosphorylation of GATA4 serine 105 but not serine 261 is required for testosterone production in the male mouse.
Volume: 7
Issue: 3
Pages: 357-372
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Publication
7588260 | J:29763
First Author: Compagnone NA
Year: 1995
Journal: Endocrinology
Title: Steroidogenic enzyme P450c17 is expressed in the embryonic central nervous system.
Volume: 136
Issue: 11
Pages: 5212-23
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Publication
19268447 | J:147876
First Author: Barsoum IB
Year: 2009
Journal: Dev Biol
Title: Activation of the Hedgehog pathway in the mouse fetal ovary leads to ectopic appearance of fetal Leydig cells and female pseudohermaphroditism.
Volume: 329
Issue: 1
Pages: 96-103
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Publication
21900680 | J:185786
First Author: Chawengsaksophak K
Year: 2012
Journal: Biol Reprod
Title: Loss of Wnt5a disrupts primordial germ cell migration and male sexual development in mice.
Volume: 86
Issue: 1
Pages: 1-12
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Publication
37727456 | J:340792
 
First Author: Whiley PAF
Year: 2023
Journal: Front Endocrinol (Lausanne)
Title: Testis exposure to unopposed/elevated activin A in utero affects somatic and germ cells and alters steroid levels mimicking phthalate exposure.
Volume: 14
Pages: 1234712
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Publication
16412416 | J:105944
First Author: Mattiske D
Year: 2006
Journal: Dev Biol
Title: The mouse forkhead gene Foxc1 is required for primordial germ cell migration and antral follicle development.
Volume: 290
Issue: 2
Pages: 447-58
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Publication
17592132 | J:122819
First Author: Tomaszewski J
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Essential roles of inhibin beta A in mouse epididymal coiling.
Volume: 104
Issue: 27
Pages: 11322-7
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Publication
23136395 | J:189958
First Author: Buaas FW
Year: 2012
Journal: Development
Title: In vivo evidence for the crucial role of SF1 in steroid-producing cells of the testis, ovary and adrenal gland.
Volume: 139
Issue: 24
Pages: 4561-70
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Publication
25713029 | J:223361
First Author: Kaftanovskaya EM
Year: 2015
Journal: FASEB J
Title: Genetic ablation of androgen receptor signaling in fetal Leydig cell lineage affects Leydig cell functions in adult testis.
Volume: 29
Issue: 6
Pages: 2327-37
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Publication
26333992 | J:227517
First Author: Koizumi M
Year: 2015
Journal: Biol Reprod
Title: Lgr4 controls specialization of female gonads in mice.
Volume: 93
Issue: 4
Pages: 90
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Publication
25917826 | J:222787
 
First Author: Liu C
Year: 2015
Journal: Nat Commun
Title: Lineage specification of ovarian theca cells requires multicellular interactions via oocyte and granulosa cells.
Volume: 6
Pages: 6934
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Publication
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