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Search results 1 to 100 out of 192 for Cyp7a1

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Category: Publication
Type Details Score
Publication
First Author: Ratliff EP
Year: 2006
Journal: J Lipid Res
Title: Transgenic expression of CYP7A1 in LDL receptor-deficient mice blocks diet-induced hypercholesterolemia.
Volume: 47
Issue: 7
Pages: 1513-20
Publication
First Author: Chen JY
Year: 2002
Journal: J Biol Chem
Title: Mice expressing the human CYP7A1 gene in the mouse CYP7A1 knock-out background lack induction of CYP7A1 expression by cholesterol feeding and have increased hypercholesterolemia when fed a high fat diet.
Volume: 277
Issue: 45
Pages: 42588-95
Publication
First Author: Kojima M
Year: 2009
Journal: Biochem Biophys Res Commun
Title: IL-1 regulates the Cyp7a1 gene and serum total cholesterol level at steady state in mice.
Volume: 379
Issue: 2
Pages: 239-42
Publication
First Author: Zhang L
Year: 2009
Journal: Mol Endocrinol
Title: Significance and mechanism of CYP7a1 gene regulation during the acute phase of liver regeneration.
Volume: 23
Issue: 2
Pages: 137-45
Publication
First Author: Lee EA
Year: 2018
Journal: Biochim Biophys Acta
Title: Cyp7a1 is continuously increased with disrupted Fxr-mediated feedback inhibition in hypercholesterolemic TALLYHO/Jng mice.
Volume: 1863
Issue: 1
Pages: 20-25
Publication
First Author: Chow EC
Year: 2014
Journal: Gastroenterology
Title: Vitamin D receptor activation down-regulates the small heterodimer partner and increases CYP7A1 to lower cholesterol.
Volume: 146
Issue: 4
Pages: 1048-59
Publication
First Author: Ponugoti B
Year: 2007
Journal: Mol Endocrinol
Title: Functional interaction of hepatic nuclear factor-4 and peroxisome proliferator-activated receptor-gamma coactivator 1alpha in CYP7A1 regulation is inhibited by a key lipogenic activator, sterol regulatory element-binding protein-1c.
Volume: 21
Issue: 11
Pages: 2698-712
Publication
First Author: Machleder D
Year: 1997
Journal: J Clin Invest
Title: Complex genetic control of HDL levels in mice in response to an atherogenic diet. Coordinate regulation of HDL levels and bile acid metabolism.
Volume: 99
Issue: 6
Pages: 1406-19
Publication
First Author: Miyake JH
Year: 2001
Journal: J Biol Chem
Title: Increased production of apolipoprotein B-containing lipoproteins in the absence of hyperlipidemia in transgenic mice expressing cholesterol 7alpha-hydroxylase.
Volume: 276
Issue: 26
Pages: 23304-11
Publication
First Author: Li T
Year: 2013
Journal: Hepatology
Title: Regulation of cholesterol and bile acid homeostasis by the cholesterol 7α-hydroxylase/steroid response element-binding protein 2/microRNA-33a axis in mice.
Volume: 58
Issue: 3
Pages: 1111-21
Publication
First Author: Tzung KW
Year: 1994
Journal: Genomics
Title: Structure of the mouse cholesterol 7 alpha-hydroxylase gene.
Volume: 21
Issue: 1
Pages: 244-7
Publication
First Author: Erickson SK
Year: 2003
Journal: J Lipid Res
Title: Hypercholesterolemia and changes in lipid and bile acid metabolism in male and female cyp7A1-deficient mice.
Volume: 44
Issue: 5
Pages: 1001-9
Publication
First Author: Tiemann M
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Cholesterol feeding of mice expressing cholesterol 7alpha-hydroxylase increases bile acid pool size despite decreased enzyme activity.
Volume: 101
Issue: 7
Pages: 1846-51
Publication
First Author: Agellon LB
Year: 2002
Journal: J Biol Chem
Title: Dietary cholesterol fails to stimulate the human cholesterol 7alpha-hydroxylase gene (CYP7A1) in transgenic mice.
Volume: 277
Issue: 23
Pages: 20131-4
Publication
First Author: Post SM
Year: 2004
Journal: Arterioscler Thromb Vasc Biol
Title: Cholesterol 7alpha-hydroxylase deficiency in mice on an APOE*3-Leiden background impairs very-low-density lipoprotein production.
Volume: 24
Issue: 4
Pages: 768-74
Publication
First Author: Cheema SK
Year: 2000
Journal: J Biol Chem
Title: The murine and human cholesterol 7alpha-hydroxylase gene promoters are differentially responsive to regulation by fatty acids mediated via peroxisome proliferator-activated receptor alpha.
Volume: 275
Issue: 17
Pages: 12530-6
Publication
First Author: Liu H
Year: 2016
Journal: J Lipid Res
Title: Cholesterol 7α-hydroxylase protects the liver from inflammation and fibrosis by maintaining cholesterol homeostasis.
Volume: 57
Issue: 10
Pages: 1831-1844
Publication
First Author: Chen PC
Year: 2023
Journal: Am J Pathol
Title: miR-194 Up-Regulates Cholesterol 7 Alpha-Hydroxylase Expression via β-Catenin Signaling and Aggravates Cholestatic Liver Diseases.
Volume: 193
Issue: 6
Pages: 755-768
Publication
First Author: Li-Hawkins J
Year: 2002
Journal: J Clin Invest
Title: Cholic acid mediates negative feedback regulation of bile acid synthesis in mice.
Volume: 110
Issue: 8
Pages: 1191-200
Publication
First Author: Schwarz M
Year: 2001
Journal: J Lipid Res
Title: Alternate pathways of bile acid synthesis in the cholesterol 7alpha-hydroxylase knockout mouse are not upregulated by either cholesterol or cholestyramine feeding.
Volume: 42
Issue: 10
Pages: 1594-603
Publication
First Author: Liu X
Year: 2017
Journal: J Lipid Res
Title: Hepatic deletion of X-box binding protein 1 impairs bile acid metabolism in mice.
Volume: 58
Issue: 3
Pages: 504-511
Publication  
First Author: Patel DD
Year: 2000
Journal: Biochem J
Title: The effect of peroxisome-proliferator-activated receptor-alpha on the activity of the cholesterol 7 alpha-hydroxylase gene.
Volume: 351 Pt 3
Pages: 747-53
Publication
First Author: Kurosu H
Year: 2007
Journal: J Biol Chem
Title: Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21.
Volume: 282
Issue: 37
Pages: 26687-95
Publication
First Author: Li T
Year: 2012
Journal: J Biol Chem
Title: Glucose and insulin induction of bile acid synthesis: mechanisms and implication in diabetes and obesity.
Volume: 287
Issue: 3
Pages: 1861-73
Publication
First Author: Krishnamurthy K
Year: 2016
Journal: Cardiovasc Res
Title: Heat shock factor-1 knockout enhances cholesterol 7α-hydroxylase (CYP7A1) and multidrug transporter (MDR1) gene expressions to attenuate atherosclerosis.
Volume: 111
Issue: 1
Pages: 74-83
Publication
First Author: Post SM
Year: 2006
Journal: Arterioscler Thromb Vasc Biol
Title: Cholesterol 7alpha-hydroxylase deficiency in mice on an APOE*3-Leiden background increases hepatic ABCA1 mRNA expression and HDL-cholesterol.
Volume: 26
Issue: 12
Pages: 2724-30
Publication
First Author: Xie Y
Year: 2009
Journal: J Biol Chem
Title: Decreased expression of cholesterol 7alpha-hydroxylase and altered bile acid metabolism in Apobec-1-/- mice lead to increased gallstone susceptibility.
Volume: 284
Issue: 25
Pages: 16860-71
Publication
First Author: Vergnes L
Year: 2013
Journal: Cell Metab
Title: Diet1 functions in the FGF15/19 enterohepatic signaling axis to modulate bile acid and lipid levels.
Volume: 17
Issue: 6
Pages: 916-28
Publication
First Author: Lan T
Year: 2013
Journal: Atherosclerosis
Title: Inhibition of ileal apical but not basolateral bile acid transport reduces atherosclerosis in apoE⁻/⁻ mice.
Volume: 229
Issue: 2
Pages: 374-80
Publication
First Author: Paré JF
Year: 2004
Journal: J Biol Chem
Title: The fetoprotein transcription factor (FTF) gene is essential to embryogenesis and cholesterol homeostasis and is regulated by a DR4 element.
Volume: 279
Issue: 20
Pages: 21206-16
Publication
First Author: Ishibashi S
Year: 1996
Journal: J Biol Chem
Title: Disruption of cholesterol 7alpha-hydroxylase gene in mice. I. Postnatal lethality reversed by bile acid and vitamin supplementation.
Volume: 271
Issue: 30
Pages: 18017-23
Publication
First Author: Schwarz M
Year: 1998
Journal: J Lipid Res
Title: Marked reduction in bile acid synthesis in cholesterol 7alpha-hydroxylase-deficient mice does not lead to diminished tissue cholesterol turnover or to hypercholesterolemia.
Volume: 39
Issue: 9
Pages: 1833-43
Publication
First Author: Schwarz M
Year: 1996
Journal: J Biol Chem
Title: Disruption of cholesterol 7alpha-hydroxylase gene in mice. II. Bile acid deficiency is overcome by induction of oxysterol 7alpha-hydroxylase.
Volume: 271
Issue: 30
Pages: 18024-31
Publication
First Author: McMillin M
Year: 2016
Journal: Am J Pathol
Title: Bile Acid Signaling Is Involved in the Neurological Decline in a Murine Model of Acute Liver Failure.
Volume: 186
Issue: 2
Pages: 312-23
Publication  
First Author: Agellon LB
Year: 1997
Journal: Biochem J
Title: The 3'-untranslated region of the mouse cholesterol 7alpha-hydroxylase mRNA contains elements responsive to post-transcriptional regulation by bile acids.
Volume: 328 ( Pt 2)
Pages: 393-9
Publication
First Author: Lorbek G
Year: 2012
Journal: FEBS J
Title: Cytochrome P450s in the synthesis of cholesterol and bile acids--from mouse models to human diseases.
Volume: 279
Issue: 9
Pages: 1516-33
Publication
First Author: Arnon R
Year: 1998
Journal: Gastroenterology
Title: Cholesterol 7-hydroxylase knockout mouse: a model for monohydroxy bile acid-related neonatal cholestasis.
Volume: 115
Issue: 5
Pages: 1223-8
Publication
First Author: Voshol PJ
Year: 2001
Journal: Biochem J
Title: Down-regulation of intestinal scavenger receptor class B, type I (SR-BI) expression in rodents under conditions of deficient bile delivery to the intestine.
Volume: 356
Issue: Pt 2
Pages: 317-25
Publication
First Author: Faust PL
Year: 2003
Journal: J Comp Neurol
Title: Abnormal cerebellar histogenesis in PEX2 Zellweger mice reflects multiple neuronal defects induced by peroxisome deficiency.
Volume: 461
Issue: 3
Pages: 394-413
Publication
First Author: Hewitt KN
Year: 2003
Journal: Endocrinology
Title: The aromatase knockout mouse presents with a sexually dimorphic disruption to cholesterol homeostasis.
Volume: 144
Issue: 9
Pages: 3895-903
Publication
First Author: Wu MK
Year: 2005
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Altered hepatic cholesterol metabolism compensates for disruption of phosphatidylcholine transfer protein in mice.
Volume: 289
Issue: 3
Pages: G456-61
Publication
First Author: Woodruff ML
Year: 2003
Journal: Nat Genet
Title: Spontaneous activity of opsin apoprotein is a cause of Leber congenital amaurosis.
Volume: 35
Issue: 2
Pages: 158-64
Publication
First Author: Hyogo H
Year: 2002
Journal: J Biol Chem
Title: Leptin promotes biliary cholesterol elimination during weight loss in ob/ob mice by regulating the enterohepatic circulation of bile salts.
Volume: 277
Issue: 37
Pages: 34117-24
Publication
First Author: Smith AJ
Year: 1999
Journal: J Hepatol
Title: Liver gene disruptions: winners by KO?
Volume: 31
Issue: 4
Pages: 752-9
Publication
First Author: Yanagida A
Year: 2015
Journal: Dev Biol
Title: Liver maturation deficiency in p57(Kip2)-/- mice occurs in a hepatocytic p57(Kip2) expression-independent manner.
Volume: 407
Issue: 2
Pages: 331-43
Publication
First Author: Repa JJ
Year: 2000
Journal: Genes Dev
Title: Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta.
Volume: 14
Issue: 22
Pages: 2819-30
Publication
First Author: Lyons MA
Year: 2004
Journal: Physiol Genomics
Title: Quantitative trait loci that determine lipoprotein cholesterol levels in an intercross of 129S1/SvImJ and CAST/Ei inbred mice.
Volume: 17
Issue: 1
Pages: 60-8
Publication
First Author: Shih DQ
Year: 2001
Journal: Nat Genet
Title: Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism.
Volume: 27
Issue: 4
Pages: 375-82
Publication
First Author: Creasy KT
Year: 2016
Journal: Gene Expr
Title: Zinc Fingers and Homeoboxes 2 (Zhx2) Regulates Sexually Dimorphic Cyp Gene Expression in the Adult Mouse Liver.
Volume: 17
Issue: 1
Pages: 7-17
Publication
First Author: Ferrell JM
Year: 2016
Journal: J Lipid Res
Title: Cholesterol 7α-hydroxylase-deficient mice are protected from high-fat/high-cholesterol diet-induced metabolic disorders.
Volume: 57
Issue: 7
Pages: 1144-54
Publication
First Author: Rocha AS
Year: 2015
Journal: Cell Rep
Title: The Angiocrine Factor Rspondin3 Is a Key Determinant of Liver Zonation.
Volume: 13
Issue: 9
Pages: 1757-64
Publication  
First Author: Lee DH
Year: 2016
Journal: Nat Commun
Title: LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development.
Volume: 7
Pages: 11961
Publication
First Author: Hamazaki J
Year: 2015
Journal: PLoS Genet
Title: Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis.
Volume: 11
Issue: 7
Pages: e1005401
Publication
First Author: Fonseca TL
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity.
Volume: 112
Issue: 45
Pages: 14018-23
Publication  
First Author: Pantasis S
Year: 2022
Journal: J Cell Sci
Title: Vertebrate lonesome kinase modulates the hepatocyte secretome to prevent perivascular liver fibrosis and inflammation.
Volume: 135
Issue: 7
Publication  
First Author: Alpern D
Year: 2014
Journal: Elife
Title: TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation.
Volume: 3
Pages: e03613
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication
First Author: Boj SF
Year: 2012
Journal: Cell
Title: Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand.
Volume: 151
Issue: 7
Pages: 1595-607
Publication
First Author: Seth A
Year: 2014
Journal: Development
Title: Prox1 ablation in hepatic progenitors causes defective hepatocyte specification and increases biliary cell commitment.
Volume: 141
Issue: 3
Pages: 538-47
Publication
First Author: Briançon N
Year: 2006
Journal: EMBO J
Title: In vivo role of the HNF4alpha AF-1 activation domain revealed by exon swapping.
Volume: 25
Issue: 6
Pages: 1253-62
Publication
First Author: Lammert F
Year: 2001
Journal: Gastroenterology
Title: Chromosomal organization of candidate genes involved in cholesterol gallstone formation: a murine gallstone map.
Volume: 120
Issue: 1
Pages: 221-38
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniPathway vocabulary mapping
Publication        
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
Publication        
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Davis RA
Year: 2011
Journal: MGI Direct Data Submission
Title: A new transgenic mouse expressing rat Cyp7a1 in macrophages
Publication  
First Author: Xing C
Year: 2020
Journal: Front Genet
Title: Sleep Disturbance Induces Increased Cholesterol Level by NR1D1 Mediated CYP7A1 Inhibition.
Volume: 11
Pages: 610496
Publication
First Author: Zhang Y
Year: 2015
Journal: Biochem J
Title: Orphan nuclear receptor oestrogen-related receptor γ (ERRγ) plays a key role in hepatic cannabinoid receptor type 1-mediated induction of CYP7A1 gene expression.
Volume: 470
Issue: 2
Pages: 181-93
Publication
First Author: Shin DJ
Year: 2003
Journal: J Biol Chem
Title: PGC-1alpha activates CYP7A1 and bile acid biosynthesis.
Volume: 278
Issue: 50
Pages: 50047-52
Publication
First Author: Qi Y
Year: 2015
Journal: Biochim Biophys Acta
Title: Bile acid signaling in lipid metabolism: metabolomic and lipidomic analysis of lipid and bile acid markers linked to anti-obesity and anti-diabetes in mice.
Volume: 1851
Issue: 1
Pages: 19-29
Publication
First Author: Li T
Year: 2010
Journal: Hepatology
Title: Transgenic expression of cholesterol 7alpha-hydroxylase in the liver prevents high-fat diet-induced obesity and insulin resistance in mice.
Volume: 52
Issue: 2
Pages: 678-90