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Search results 1 to 100 out of 149 for Egln3

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Category: Publication
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Type Details Score
Publication
- | J:70781
   
First Author: Taylor MS
Year: 2001
Journal: GenBank Submission
Title: Mus musculus mRNA for EGLN3 protein
Pages: AJ310548
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Publication
17344222 | J:121285
First Author: Fu J
Year: 2007
Journal: J Biol Chem
Title: EGLN3 prolyl hydroxylase regulates skeletal muscle differentiation and myogenin protein stability.
Volume: 282
Issue: 17
Pages: 12410-8
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Publication
31375625 | J:278746
First Author: Li S
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance.
Volume: 116
Issue: 34
Pages: 16997-17006
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Publication
35124697 | J:322768
First Author: Jin Y
Year: 2022
Journal: Oncogene
Title: Inactivation of EGLN3 hydroxylase facilitates Erk3 degradation via autophagy and impedes lung cancer growth.
Volume: 41
Issue: 12
Pages: 1752-1766
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Publication
18334619 | J:280033
First Author: Schlisio S
Year: 2008
Journal: Genes Dev
Title: The kinesin KIF1Bbeta acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor.
Volume: 22
Issue: 7
Pages: 884-93
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Publication
21317538 | J:172036
First Author: Walmsley SR
Year: 2011
Journal: J Clin Invest
Title: Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice.
Volume: 121
Issue: 3
Pages: 1053-63
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Publication
19720742 | J:153985
First Author: Minamishima YA
Year: 2009
Journal: Mol Cell Biol
Title: A feedback loop involving the Phd3 prolyl hydroxylase tunes the mammalian hypoxic response in vivo.
Volume: 29
Issue: 21
Pages: 5729-41
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Publication
18332118 | J:136034
First Author: Bishop T
Year: 2008
Journal: Mol Cell Biol
Title: Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice.
Volume: 28
Issue: 10
Pages: 3386-400
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Publication
10543731 | J:60099
First Author: Moschella MC
Year: 1999
Journal: Gene Expr
Title: SM-20 is a novel growth factor-responsive gene regulated during skeletal muscle development and differentiation.
Volume: 8
Issue: 1
Pages: 59-66
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Publication
11574160 | J:72041
First Author: Taylor MS
Year: 2001
Journal: Gene
Title: Characterization and comparative analysis of the EGLN gene family.
Volume: 275
Issue: 1
Pages: 125-32
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Publication
19584355 | -
First Author: Xie L
Year: 2009
Journal: Sci Signal
Title: Oxygen-regulated beta(2)-adrenergic receptor hydroxylation by EGLN3 and ubiquitylation by pVHL.
Volume: 2
Issue: 78
Pages: ra33
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Publication
33951416 | J:306906
First Author: Zhu B
Year: 2021
Journal: Immunity
Title: Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection.
Volume: 54
Issue: 6
Pages: 1200-1218.e9
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Publication
25633836 | J:225762
 
First Author: Xie L
Year: 2015
Journal: J Mol Cell Cardiol
Title: Depletion of PHD3 protects heart from ischemia/reperfusion injury by inhibiting cardiomyocyte apoptosis.
Volume: 80
Pages: 156-65
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Publication
31092600 | J:280720
First Author: Xu Y
Year: 2019
Journal: J Biol Chem
Title: Prolyl hydroxylase 3 stabilizes the p53 tumor suppressor by inhibiting the p53-MDM2 interaction in a hydroxylase-independent manner.
Volume: 294
Issue: 25
Pages: 9949-9958
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Publication
34571849 | J:312547
 
First Author: Xing W
Year: 2021
Journal: Cells
Title: Prolyl Hydroxylase Domain-Containing Protein 3 Gene Expression in Chondrocytes Is Not Essential for Bone Development in Mice.
Volume: 10
Issue: 9
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Publication
28495754 | J:252685
First Author: Schoepflin ZR
Year: 2017
Journal: FASEB J
Title: PHD3 is a transcriptional coactivator of HIF-1α in nucleus pulposus cells independent of the PKM2-JMJD5 axis.
Volume: 31
Issue: 9
Pages: 3831-3847
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Publication
37252972 | J:343092
First Author: Xue Y
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Proline hydroxylation of CREB-regulated transcriptional coactivator 2 controls hepatic glucose metabolism.
Volume: 120
Issue: 23
Pages: e2219419120
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Publication
22797300 | J:190073
First Author: Xie L
Year: 2012
Journal: J Clin Invest
Title: PHD3-dependent hydroxylation of HCLK2 promotes the DNA damage response.
Volume: 122
Issue: 8
Pages: 2827-36
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Publication
34264866 | J:312995
 
First Author: Nasteska D
Year: 2021
Journal: JCI Insight
Title: Prolyl-4-hydroxylase 3 maintains β cell glucose metabolism during fatty acid excess in mice.
Volume: 6
Issue: 16
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Publication
26124271 | J:224600
First Author: Chen Y
Year: 2015
Journal: J Biol Chem
Title: PHD3 Stabilizes the Tight Junction Protein Occludin and Protects Intestinal Epithelial Barrier Function.
Volume: 290
Issue: 33
Pages: 20580-9
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Publication
27635760 | J:248932
First Author: German NJ
Year: 2016
Journal: Mol Cell
Title: PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2.
Volume: 63
Issue: 6
Pages: 1006-20
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Publication
30250231 | J:267495
First Author: Yano H
Year: 2018
Journal: Sci Rep
Title: PHD3 regulates glucose metabolism by suppressing stress-induced signalling and optimising gluconeogenesis and insulin signalling in hepatocytes.
Volume: 8
Issue: 1
Pages: 14290
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Publication
24626957 | J:218623
First Author: Swain L
Year: 2014
Journal: J Leukoc Biol
Title: Prolyl-4-hydroxylase domain 3 (PHD3) is a critical terminator for cell survival of macrophages under stress conditions.
Volume: 96
Issue: 3
Pages: 365-75
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37140003 | J:338024
First Author: Rosiewicz KS
Year: 2023
Journal: Glia
Title: HIF prolyl hydroxylase 2/3 deletion disrupts astrocytic integrity and exacerbates neuroinflammation.
Volume: 71
Issue: 8
Pages: 2024-2044
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Publication
33023907 | J:299411
First Author: Heidenreich S
Year: 2020
Journal: J Biol Chem
Title: The glucose-sensing transcription factor ChREBP is targeted by proline hydroxylation.
Volume: 295
Issue: 50
Pages: 17158-17168
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Publication
25420773 | J:225283
 
First Author: Henze AT
Year: 2014
Journal: Nat Commun
Title: Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR.
Volume: 5
Pages: 5582
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Publication
26995088 | J:234814
First Author: Liu H
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Prolyl hydroxylase 3 overexpression accelerates the progression of atherosclerosis in ApoE-/- mice.
Volume: 473
Issue: 1
Pages: 99-106
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Publication
28939592 | J:269630
First Author: Cai X
Year: 2018
Journal: FASEB J
Title: α-Ketoglutarate prevents skeletal muscle protein degradation and muscle atrophy through PHD3/ADRB2 pathway.
Volume: 32
Issue: 1
Pages: 488-499
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Publication
25385837 | J:229209
First Author: Macías D
Year: 2014
Journal: EMBO Mol Med
Title: Deletion of the von Hippel-Lindau gene causes sympathoadrenal cell death and impairs chemoreceptor-mediated adaptation to hypoxia.
Volume: 6
Issue: 12
Pages: 1577-92
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Publication
20733101 | J:179490
First Author: Moslehi J
Year: 2010
Journal: Circulation
Title: Loss of hypoxia-inducible factor prolyl hydroxylase activity in cardiomyocytes phenocopies ischemic cardiomyopathy.
Volume: 122
Issue: 10
Pages: 1004-16
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26774962 | J:232857
First Author: Quaegebeur A
Year: 2016
Journal: Cell Metab
Title: Deletion or Inhibition of the Oxygen Sensor PHD1 Protects against Ischemic Stroke via Reprogramming of Neuronal Metabolism.
Volume: 23
Issue: 2
Pages: 280-91
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Publication
32814068 | J:301250
 
First Author: Smaila BD
Year: 2020
Journal: Exp Neurol
Title: Systemic hypoxia mimicry enhances axonal regeneration and functional recovery following peripheral nerve injury.
Volume: 334
Pages: 113436
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24440788 | J:206444
First Author: Takeda K
Year: 2014
Journal: Am J Pathol
Title: Improved vascular survival and growth in the mouse model of hindlimb ischemia by a remote signaling mechanism.
Volume: 184
Issue: 3
Pages: 686-96
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Publication
24508125 | J:208042
First Author: Duan LJ
Year: 2014
Journal: Am J Pathol
Title: Hematological, hepatic, and retinal phenotypes in mice deficient for prolyl hydroxylase domain proteins in the liver.
Volume: 184
Issue: 4
Pages: 1240-50
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Publication
27981571 | J:241898
First Author: Van Welden S
Year: 2017
Journal: J Pathol
Title: Haematopoietic prolyl hydroxylase-1 deficiency promotes M2 macrophage polarization and is both necessary and sufficient to protect against experimental colitis.
Volume: 241
Issue: 4
Pages: 547-558
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17646578 | J:133568
First Author: Takeda K
Year: 2007
Journal: Circulation
Title: Essential role for prolyl hydroxylase domain protein 2 in oxygen homeostasis of the adult vascular system.
Volume: 116
Issue: 7
Pages: 774-81
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18056838 | J:132720
First Author: Takeda K
Year: 2008
Journal: Blood
Title: Regulation of adult erythropoiesis by prolyl hydroxylase domain proteins.
Volume: 111
Issue: 6
Pages: 3229-35
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26075818 | J:225429
First Author: Xie L
Year: 2015
Journal: J Clin Invest
Title: PHD2/3-dependent hydroxylation tunes cardiac response to β-adrenergic stress via phospholamban.
Volume: 125
Issue: 7
Pages: 2759-71
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33464382 | J:306672
First Author: Watts D
Year: 2021
Journal: Cell Mol Life Sci
Title: HIF1α is a direct regulator of steroidogenesis in the adrenal gland.
Volume: 78
Issue: 7
Pages: 3577-3590
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33819286 | J:304962
First Author: Wei GZ
Year: 2021
Journal: PLoS One
Title: Hypoxia-inducible factor prolyl hydroxylase domain (PHD) inhibition after contusive spinal cord injury does not improve locomotor recovery.
Volume: 16
Issue: 4
Pages: e0249591
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26818499 | J:229447
First Author: Rajagopalan S
Year: 2016
Journal: J Neurosci
Title: Regulation of ATP13A2 via PHD2-HIF1α Signaling Is Critical for Cellular Iron Homeostasis: Implications for Parkinson's Disease.
Volume: 36
Issue: 4
Pages: 1086-95
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22786772 | J:189753
First Author: Kiss J
Year: 2012
Journal: J Immunol
Title: Loss of the oxygen sensor PHD3 enhances the innate immune response to abdominal sepsis.
Volume: 189
Issue: 4
Pages: 1955-65
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22615432 | J:200057
First Author: Chen RL
Year: 2012
Journal: J Physiol
Title: Roles of individual prolyl-4-hydroxylase isoforms in the first 24 hours following transient focal cerebral ischaemia: insights from genetically modified mice.
Volume: 590
Issue: 16
Pages: 4079-91
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30248340 | J:270770
First Author: Strowitzki MJ
Year: 2018
Journal: Am J Pathol
Title: Loss of Prolyl-Hydroxylase 1 Protects against Biliary Fibrosis via Attenuated Activation of Hepatic Stellate Cells.
Volume: 188
Issue: 12
Pages: 2826-2838
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Publication
27614241 | J:237383
First Author: Zhu K
Year: 2016
Journal: Gene
Title: Prolyl hydroxylase domain proteins regulate bone mass through their expression in osteoblasts.
Volume: 594
Issue: 1
Pages: 125-130
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Publication
27561929 | J:241612
 
First Author: Chowdhury R
Year: 2016
Journal: Nat Commun
Title: Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases.
Volume: 7
Pages: 12673
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Publication
31029587 | J:274809
 
First Author: Leinonen H
Year: 2019
Journal: Neuropharmacology
Title: Null mutation in P4h-tm leads to decreased fear and anxiety and increased social behavior in mice.
Volume: 153
Pages: 63-72
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28716863 | J:247886
First Author: Tavernier SJ
Year: 2017
Journal: J Leukoc Biol
Title: Opposing regulation and roles for PHD3 in lung dendritic cells and alveolar macrophages.
Volume: 102
Issue: 4
Pages: 1115-1126
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Publication
36509284 | J:332130
 
First Author: Kennel KB
Year: 2022
Journal: JCI Insight
Title: The HIF-prolyl hydroxylases have distinct and nonredundant roles in colitis-associated cancer.
Volume: 7
Issue: 22
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23690557 | J:212783
First Author: Bishop T
Year: 2013
Journal: J Physiol
Title: Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2.
Volume: 591
Issue: 14
Pages: 3565-77
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28418093 | J:243598
First Author: Hulley PA
Year: 2017
Journal: J Pathol
Title: Hypoxia-inducible factor 1-alpha does not regulate osteoclastogenesis but enhances bone resorption activity via prolyl-4-hydroxylase 2.
Volume: 242
Issue: 3
Pages: 322-333
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20600011 | J:309903
First Author: Tambuwala MM
Year: 2010
Journal: Gastroenterology
Title: Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function.
Volume: 139
Issue: 6
Pages: 2093-101
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24037093 | J:202021
First Author: Taniguchi CM
Year: 2013
Journal: Nat Med
Title: Cross-talk between hypoxia and insulin signaling through Phd3 regulates hepatic glucose and lipid metabolism and ameliorates diabetes.
Volume: 19
Issue: 10
Pages: 1325-30
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33298456 | J:313923
 
First Author: Byts N
Year: 2021
Journal: eNeuro
Title: Transmembrane Prolyl 4-Hydroxylase is a Novel Regulator of Calcium Signaling in Astrocytes.
Volume: 8
Issue: 1
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22955912 | J:213191
First Author: Laitala A
Year: 2012
Journal: Blood
Title: Transmembrane prolyl 4-hydroxylase is a fourth prolyl 4-hydroxylase regulating EPO production and erythropoiesis.
Volume: 120
Issue: 16
Pages: 3336-44
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22262480 | J:183424
First Author: Kapitsinou PP
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Preischemic targeting of HIF prolyl hydroxylation inhibits fibrosis associated with acute kidney injury.
Volume: 302
Issue: 9
Pages: F1172-9
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Publication
25446011 | J:319086
 
First Author: Rishi MT
Year: 2015
Journal: Microvasc Res
Title: Deletion of prolyl hydroxylase domain proteins (PHD1, PHD3) stabilizes hypoxia inducible factor-1 alpha, promotes neovascularization, and improves perfusion in a murine model of hind-limb ischemia.
Volume: 97
Pages: 181-8
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Publication
28538180 | J:254708
First Author: Yoshinaga M
Year: 2017
Journal: Cell Rep
Title: Regnase-1 Maintains Iron Homeostasis via the Degradation of Transferrin Receptor 1 and Prolyl-Hydroxylase-Domain-Containing Protein 3 mRNAs.
Volume: 19
Issue: 8
Pages: 1614-1630
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Publication
27795296 | J:242994
 
First Author: Guentsch A
Year: 2017
Journal: Mol Cell Biol
Title: PHD2 Is a Regulator for Glycolytic Reprogramming in Macrophages.
Volume: 37
Issue: 1
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34610308 | J:326966
First Author: Angelini A
Year: 2021
Journal: Cell Rep
Title: PHDs/CPT1B/VDAC1 axis regulates long-chain fatty acid oxidation in cardiomyocytes.
Volume: 37
Issue: 1
Pages: 109767
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Publication
23264599 | J:194598
First Author: Franke K
Year: 2013
Journal: Blood
Title: HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis.
Volume: 121
Issue: 8
Pages: 1436-45
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22611156 | J:189129
First Author: Querbes W
Year: 2012
Journal: Blood
Title: Treatment of erythropoietin deficiency in mice with systemically administered siRNA.
Volume: 120
Issue: 9
Pages: 1916-22
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34718519 | J:323854
 
First Author: Hoang M
Year: 2022
Journal: Endocrinology
Title: Isoform-specific Roles of Prolyl Hydroxylases in the Regulation of Pancreatic β-Cell Function.
Volume: 163
Issue: 1
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24030251 | J:211224
First Author: Bondeva T
Year: 2013
Journal: Mol Endocrinol
Title: Advanced glycated end-products affect HIF-transcriptional activity in renal cells.
Volume: 27
Issue: 11
Pages: 1918-33
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15210114 | J:91356
First Author: Nakayama K
Year: 2004
Journal: Cell
Title: Siah2 regulates stability of prolyl-hydroxylases, controls HIF1alpha abundance, and modulates physiological responses to hypoxia.
Volume: 117
Issue: 7
Pages: 941-52
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24145445 | J:202913
First Author: Scholz CC
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Regulation of IL-1β-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways.
Volume: 110
Issue: 46
Pages: 18490-5
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18176562 | J:132630
First Author: Aragonés J
Year: 2008
Journal: Nat Genet
Title: Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism.
Volume: 40
Issue: 2
Pages: 170-80
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22014577 | J:177485
First Author: Adam J
Year: 2011
Journal: Cancer Cell
Title: Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling.
Volume: 20
Issue: 4
Pages: 524-37
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37400498 | J:341078
First Author: Zhang T
Year: 2023
Journal: Nat Cell Biol
Title: Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation.
Volume: 25
Issue: 7
Pages: 950-962
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22464323 | J:186085
First Author: Rankin EB
Year: 2012
Journal: Cell
Title: The HIF signaling pathway in osteoblasts directly modulates erythropoiesis through the production of EPO.
Volume: 149
Issue: 1
Pages: 63-74
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20651146 | J:162614
First Author: Minamishima YA
Year: 2010
Journal: Science
Title: Reactivation of hepatic EPO synthesis in mice after PHD loss.
Volume: 329
Issue: 5990
Pages: 407
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32663458 | J:296608
First Author: Yoon H
Year: 2020
Journal: Cell Metab
Title: PHD3 Loss Promotes Exercise Capacity and Fat Oxidation in Skeletal Muscle.
Volume: 32
Issue: 2
Pages: 215-228.e7
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Publication
26054543 | J:293573
First Author: Souma T
Year: 2016
Journal: J Am Soc Nephrol
Title: Erythropoietin Synthesis in Renal Myofibroblasts Is Restored by Activation of Hypoxia Signaling.
Volume: 27
Issue: 2
Pages: 428-38
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38518771 | J:351589
First Author: Nolan ND
Year: 2024
Journal: Cell Rep Med
Title: CRISPR editing of anti-anemia drug target rescues independent preclinical models of retinitis pigmentosa.
Volume: 5
Issue: 4
Pages: 101459
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23649506 | J:244618
First Author: Zhu K
Year: 2013
Journal: J Bone Miner Res
Title: ATF4 promotes bone angiogenesis by increasing VEGF expression and release in the bone environment.
Volume: 28
Issue: 9
Pages: 1870-1884
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27565342 | J:234541
First Author: Clever D
Year: 2016
Journal: Cell
Title: Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche.
Volume: 166
Issue: 5
Pages: 1117-1131.e14
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25846796 | J:221580
First Author: Wu C
Year: 2015
Journal: Genes Dev
Title: Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin.
Volume: 29
Issue: 8
Pages: 817-31
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27088801 | J:234932
First Author: Kobayashi H
Year: 2016
Journal: J Clin Invest
Title: Distinct subpopulations of FOXD1 stroma-derived cells regulate renal erythropoietin.
Volume: 126
Issue: 5
Pages: 1926-38
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18347341 | J:133348
First Author: Ginouvès A
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: PHDs overactivation during chronic hypoxia "desensitizes" HIFalpha and protects cells from necrosis.
Volume: 105
Issue: 12
Pages: 4745-50
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18040029 | J:142981
First Author: Chang EI
Year: 2007
Journal: Circulation
Title: Age decreases endothelial progenitor cell recruitment through decreases in hypoxia-inducible factor 1alpha stabilization during ischemia.
Volume: 116
Issue: 24
Pages: 2818-29
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24828078 | J:215343
First Author: Taniguchi CM
Year: 2014
Journal: Sci Transl Med
Title: PHD inhibition mitigates and protects against radiation-induced gastrointestinal toxicity via HIF2.
Volume: 6
Issue: 236
Pages: 236ra64
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27683416 | J:237355
First Author: Urrutia AA
Year: 2016
Journal: Blood
Title: Prolyl-4-hydroxylase 2 and 3 coregulate murine erythropoietin in brain pericytes.
Volume: 128
Issue: 21
Pages: 2550-2560
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20926767 | J:166934
First Author: Trollmann R
Year: 2010
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Late-gestational systemic hypoxia leads to a similar early gene response in mouse placenta and developing brain.
Volume: 299
Issue: 6
Pages: R1489-99
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37509073 | J:338819
 
First Author: Wulf S
Year: 2023
Journal: Biomolecules
Title: Targeted Disruption of the MORG1 Gene in Mice Causes Embryonic Resorption in Early Phase of Development.
Volume: 13
Issue: 7
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Publication
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