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Search results 1 to 100 out of 199 for Fbxw7

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Type Details Score
Publication
22848434 | J:189707
First Author: Izumi N
Year: 2012
Journal: PLoS One
Title: Fbxw7 controls angiogenesis by regulating endothelial Notch activity.
Volume: 7
Issue: 7
Pages: e41116
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Publication
27764699 | J:320224
First Author: Zhang Q
Year: 2016
Journal: Neoplasia
Title: Fbxw7 Deletion Accelerates KrasG12D-Driven Pancreatic Tumorigenesis via Yap Accumulation.
Volume: 18
Issue: 11
Pages: 666-673
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Publication
23518349 | J:197046
First Author: Takeishi S
Year: 2013
Journal: Cancer Cell
Title: Ablation of Fbxw7 eliminates leukemia-initiating cells by preventing quiescence.
Volume: 23
Issue: 3
Pages: 347-61
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Publication
26774286 | J:232858
First Author: Zhang Q
Year: 2016
Journal: Mol Cell
Title: FBXW7 Facilitates Nonhomologous End-Joining via K63-Linked Polyubiquitylation of XRCC4.
Volume: 61
Issue: 3
Pages: 419-433
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Publication
34998785 | J:320419
 
First Author: Li R
Year: 2022
Journal: Dev Biol
Title: E3 ubiquitin ligase FBXW7 balances airway cell fates.
Volume: 483
Pages: 89-97
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Publication
25555218 | J:220397
First Author: Yumimoto K
Year: 2015
Journal: J Clin Invest
Title: F-box protein FBXW7 inhibits cancer metastasis in a non-cell-autonomous manner.
Volume: 125
Issue: 2
Pages: 621-35
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Publication
35069531 | J:318845
 
First Author: He J
Year: 2021
Journal: Front Immunol
Title: Myeloid Fbxw7 Prevents Pulmonary Fibrosis by Suppressing TGF-β Production.
Volume: 12
Pages: 760138
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Publication
36104351 | J:330850
First Author: Gong L
Year: 2022
Journal: Cell Death Dis
Title: FBXW7 inactivation induces cellular senescence via accumulation of p53.
Volume: 13
Issue: 9
Pages: 788
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Publication
31246581 | J:325935
First Author: He J
Year: 2019
Journal: J Clin Invest
Title: Fbxw7 increases CCL2/7 in CX3CR1hi macrophages to promote intestinal inflammation.
Volume: 129
Issue: 9
Pages: 3877-3893
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Publication
21503901 | J:172214
First Author: Davis H
Year: 2011
Journal: J Pathol
Title: FBXW7 mutations typically found in human cancers are distinct from null alleles and disrupt lung development.
Volume: 224
Issue: 2
Pages: 180-9
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Publication
33260160 | J:305978
First Author: Zhong L
Year: 2020
Journal: Aging (Albany NY)
Title: E3 ligase FBXW7 restricts M2-like tumor-associated macrophage polarization by targeting c-Myc.
Volume: 12
Issue: 23
Pages: 24394-24423
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Publication
29475832 | J:261135
First Author: Zhao J
Year: 2018
Journal: Diabetes
Title: Hepatic F-Box Protein FBXW7 Maintains Glucose Homeostasis Through Degradation of Fetuin-A.
Volume: 67
Issue: 5
Pages: 818-830
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Publication
28422719 | J:256304
First Author: Jiang Y
Year: 2017
Journal: Oncotarget
Title: Fbxw7 haploinsufficiency loses its protection against DNA damage and accelerates MNU-induced gastric carcinogenesis.
Volume: 8
Issue: 20
Pages: 33444-33456
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Publication
18787170 | J:138766
First Author: Mao JH
Year: 2008
Journal: Science
Title: FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression.
Volume: 321
Issue: 5895
Pages: 1499-502
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Publication
23791182 | J:200006
First Author: King B
Year: 2013
Journal: Cell
Title: The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability.
Volume: 153
Issue: 7
Pages: 1552-66
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Publication
28287082 | J:244688
 
First Author: Song Y
Year: 2017
Journal: Nat Commun
Title: E3 ligase FBXW7 is critical for RIG-I stabilization during antiviral responses.
Volume: 8
Pages: 14654
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Publication
33070870 | J:312820
First Author: Meyer AE
Year: 2020
Journal: Neoplasia
Title: Loss of Fbxw7 triggers mammary tumorigenesis associated with E2F/c-Myc activation and Trp53 mutation.
Volume: 22
Issue: 11
Pages: 644-658
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Publication
37843504 | J:343877
First Author: Song Y
Year: 2023
Journal: J Immunol
Title: Epigenetic Regulation of IL-23 by E3 Ligase FBXW7 in Dendritic Cells Is Critical for Psoriasis-like Inflammation.
Volume: 211
Issue: 11
Pages: 1701-1713
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Publication
29633504 | J:325934
First Author: Xiao Y
Year: 2018
Journal: Mol Oncol
Title: FBXW7 deletion contributes to lung tumor development and confers resistance to gefitinib therapy.
Volume: 12
Issue: 6
Pages: 883-895
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Publication
31883011 | J:289161
First Author: Zhang H
Year: 2020
Journal: Biol Reprod
Title: Loss of Fbxw7 in Sertoli cells impairs testis development and causes infertility in mice†.
Volume: 102
Issue: 4
Pages: 963-974
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Publication
39031722 | J:352093
First Author: Zhao H
Year: 2024
Journal: J Cell Mol Med
Title: Deletion of Fbxw7 in oocytes causes follicle loss and premature ovarian insufficiency in mice.
Volume: 28
Issue: 12
Pages: e18487
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Publication
22897623 | J:213966
First Author: Okita Y
Year: 2012
Journal: Genes Cells
Title: Increased efficiency in the generation of induced pluripotent stem cells by Fbxw7 ablation.
Volume: 17
Issue: 9
Pages: 768-77
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Publication
30275535 | J:295584
First Author: Chong Z
Year: 2018
Journal: Cell Mol Immunol
Title: E3 ligase FBXW7 aggravates TMPD-induced systemic lupus erythematosus by promoting cell apoptosis.
Volume: 15
Issue: 12
Pages: 1057-1070
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18367647 | J:133773
First Author: Matsuoka S
Year: 2008
Journal: Genes Dev
Title: Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL.
Volume: 22
Issue: 8
Pages: 986-91
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20534483 | J:161392
First Author: Bengoechea-Alonso MT
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: The ubiquitin ligase Fbxw7 controls adipocyte differentiation by targeting C/EBPalpha for degradation.
Volume: 107
Issue: 26
Pages: 11817-22
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Publication
28581198 | J:320946
First Author: Aydin IT
Year: 2017
Journal: Pigment Cell Melanoma Res
Title: FBXW7 inactivation in a BrafV600E -driven mouse model leads to melanoma development.
Volume: 30
Issue: 6
Pages: 571-574
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33234509 | J:300141
First Author: Onoyama I
Year: 2020
Journal: Cancer Res
Title: Loss of Fbxw7 Impairs Development of and Induces Heterogeneous Tumor Formation in the Mouse Mammary Gland.
Volume: 80
Issue: 24
Pages: 5515-5530
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Publication
22513362 | J:205391
First Author: Kwon YW
Year: 2012
Journal: Mol Cancer Res
Title: Pten regulates Aurora-A and cooperates with Fbxw7 in modulating radiation-induced tumor development.
Volume: 10
Issue: 6
Pages: 834-44
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Publication
21282377 | J:176848
First Author: Babaei-Jadidi R
Year: 2011
Journal: J Exp Med
Title: FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation.
Volume: 208
Issue: 2
Pages: 295-312
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31772025 | J:282812
First Author: Cuevas IC
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Fbxw7 is a driver of uterine carcinosarcoma by promoting epithelial-mesenchymal transition.
Volume: 116
Issue: 51
Pages: 25880-25890
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24879440 | J:211643
First Author: Kanatsu-Shinohara M
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Skp1-Cullin-F-box (SCF)-type ubiquitin ligase FBXW7 negatively regulates spermatogonial stem cell self-renewal.
Volume: 111
Issue: 24
Pages: 8826-31
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21123947 | J:171853
First Author: Onoyama I
Year: 2011
Journal: J Clin Invest
Title: Fbxw7 regulates lipid metabolism and cell fate decisions in the mouse liver.
Volume: 121
Issue: 1
Pages: 342-54
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22348067 | J:285311
First Author: Perez-Losada J
Year: 2012
Journal: PLoS One
Title: Allele-specific deletions in mouse tumors identify Fbxw7 as germline modifier of tumor susceptibility.
Volume: 7
Issue: 2
Pages: e31301
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17984302 | J:128523
First Author: Onoyama I
Year: 2007
Journal: J Exp Med
Title: Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis.
Volume: 204
Issue: 12
Pages: 2875-88
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21076392 | J:167167
First Author: Balamurugan K
Year: 2010
Journal: EMBO J
Title: The tumour suppressor C/EBPδ inhibits FBXW7 expression and promotes mammary tumour metastasis.
Volume: 29
Issue: 24
Pages: 4106-17
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23676439 | J:197128
First Author: Davis H
Year: 2014
Journal: Gut
Title: Investigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines.
Volume: 63
Issue: 5
Pages: 792-9
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29386660 | J:258194
First Author: Ikenoue T
Year: 2018
Journal: Sci Rep
Title: Establishment and analysis of a novel mouse line carrying a conditional knockin allele of a cancer-specific FBXW7 mutation.
Volume: 8
Issue: 1
Pages: 2021
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22665065 | J:197229
First Author: Ishikawa Y
Year: 2013
Journal: Oncogene
Title: Opposing functions of Fbxw7 in keratinocyte growth, differentiation and skin tumorigenesis mediated through negative regulation of c-Myc and Notch.
Volume: 32
Issue: 15
Pages: 1921-32
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37589076 | J:341493
First Author: Brown M
Year: 2023
Journal: EMBO Mol Med
Title: Functional analysis reveals driver cooperativity and novel mechanisms in endometrial carcinogenesis.
Volume: 15
Issue: 10
Pages: e17094
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16061623 | J:100782
First Author: Perez-Losada J
Year: 2005
Journal: Cancer Res
Title: Control of genomic instability and epithelial tumor development by the p53-Fbxw7/Cdc4 pathway.
Volume: 65
Issue: 15
Pages: 6488-92
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34518642 | J:325936
First Author: Petsouki E
Year: 2021
Journal: Commun Biol
Title: FBW7 couples structural integrity with functional output of primary cilia.
Volume: 4
Issue: 1
Pages: 1066
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30783098 | J:298755
First Author: Li N
Year: 2019
Journal: Oncogenesis
Title: An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance.
Volume: 8
Issue: 3
Pages: 13
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31150734 | J:348707
 
First Author: Chen Z
Year: 2019
Journal: J Mol Cell Cardiol
Title: MiR322 mediates cardioprotection against ischemia/reperfusion injury via FBXW7/notch pathway.
Volume: 133
Pages: 67-74
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35225231 | J:327547
   
First Author: Thirimanne HN
Year: 2022
Journal: Elife
Title: Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations.
Volume: 11
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27238018 | J:271692
First Author: Zhao X
Year: 2016
Journal: Cell
Title: Circadian Amplitude Regulation via FBXW7-Targeted REV-ERBα Degradation.
Volume: 165
Issue: 7
Pages: 1644-1657
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Publication
37914694 | J:342224
First Author: Xia H
Year: 2023
Journal: Nat Commun
Title: Hepatocyte FBXW7-dependent activity of nutrient-sensing nuclear receptors controls systemic energy homeostasis and NASH progression in male mice.
Volume: 14
Issue: 1
Pages: 6982
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Publication
23454868 | J:267894
First Author: Liu Y
Year: 2013
Journal: Aging (Albany NY)
Title: Temporal mTOR inhibition protects Fbxw7-deficient mice from radiation-induced tumor development.
Volume: 5
Issue: 2
Pages: 111-9
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31278268 | J:294393
First Author: Harty BL
Year: 2019
Journal: Nat Commun
Title: Myelinating Schwann cells ensheath multiple axons in the absence of E3 ligase component Fbxw7.
Volume: 10
Issue: 1
Pages: 2976
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24446488 | J:208344
First Author: Hu J
Year: 2014
Journal: J Exp Med
Title: Müller glia cells regulate Notch signaling and retinal angiogenesis via the generation of 19,20-dihydroxydocosapentaenoic acid.
Volume: 211
Issue: 2
Pages: 281-95
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21205095 | J:297018
First Author: Matsumoto A
Year: 2011
Journal: Cancer Sci
Title: Fbxw7β resides in the endoplasmic reticulum membrane and protects cells from oxidative stress.
Volume: 102
Issue: 4
Pages: 749-55
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35440636 | J:342225
First Author: Xia H
Year: 2022
Journal: Nat Commun
Title: Insulin action and resistance are dependent on a GSK3β-FBXW7-ERRα transcriptional axis.
Volume: 13
Issue: 1
Pages: 2105
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15592418 | J:95108
First Author: Mao JH
Year: 2004
Journal: Nature
Title: Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene.
Volume: 432
Issue: 7018
Pages: 775-9
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25918410 | J:221663
First Author: Park JH
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Inactivation of EWS reduces PGC-1α protein stability and mitochondrial homeostasis.
Volume: 112
Issue: 19
Pages: 6074-9
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22117044 | J:181784
First Author: Jen KY
Year: 2012
Journal: Blood
Title: Sequential mutations in Notch1, Fbxw7, and Tp53 in radiation-induced mouse thymic lymphomas.
Volume: 119
Issue: 3
Pages: 805-9
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26575021 | J:253418
First Author: Snijders AM
Year: 2015
Journal: Oncotarget
Title: Expression profiling reveals transcriptional regulation by Fbxw7/mTOR pathway in radiation-induced mouse thymic lymphomas.
Volume: 6
Issue: 42
Pages: 44794-805
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23955342 | J:207218
First Author: Yumimoto K
Year: 2013
Journal: J Biol Chem
Title: F-box and WD repeat domain-containing-7 (Fbxw7) protein targets endoplasmic reticulum-anchored osteogenic and chondrogenic transcriptional factors for degradation.
Volume: 288
Issue: 40
Pages: 28488-502
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29282223 | J:261891
First Author: Sakai E
Year: 2018
Journal: Cancer Res
Title: Combined Mutation of Apc, Kras, and Tgfbr2 Effectively Drives Metastasis of Intestinal Cancer.
Volume: 78
Issue: 5
Pages: 1334-1346
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21349854 | J:171254
First Author: Matsumoto A
Year: 2011
Journal: J Biol Chem
Title: Fbxw7-dependent degradation of Notch is required for control of "stemness" and neuronal-glial differentiation in neural stem cells.
Volume: 286
Issue: 15
Pages: 13754-64
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29472293 | J:262785
First Author: Nakayama S
Year: 2018
Journal: J Biol Chem
Title: Degradation of the endoplasmic reticulum-anchored transcription factor MyRF by the ubiquitin ligase SCFFbxw7 in a manner dependent on the kinase GSK-3.
Volume: 293
Issue: 15
Pages: 5705-5714
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11425854 | J:71503
First Author: Gupta-Rossi N
Year: 2001
Journal: J Biol Chem
Title: Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor.
Volume: 276
Issue: 37
Pages: 34371-8
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18474632 | J:137138
First Author: Thompson BJ
Year: 2008
Journal: J Exp Med
Title: Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7.
Volume: 205
Issue: 6
Pages: 1395-408
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22708077 | J:196027
First Author: Fukushima H
Year: 2012
Journal: Cell Rep
Title: SCF(Fbw7) modulates the NFkB signaling pathway by targeting NFkB2 for ubiquitination and destruction.
Volume: 1
Issue: 5
Pages: 434-43
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33086033 | J:300232
First Author: Wang L
Year: 2020
Journal: Cell Metab
Title: FBW7 Mediates Senescence and Pulmonary Fibrosis through Telomere Uncapping.
Volume: 32
Issue: 5
Pages: 860-877.e9
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29550488 | J:270613
First Author: Li H
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Genetic Deletion of Fbw7 in the mouse intestinal epithelium aggravated dextran sodium sulfate-induced colitis by modulating the inflammatory response of NF-κB pathway.
Volume: 498
Issue: 4
Pages: 869-876
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38485719 | J:346081
First Author: Cai Z
Year: 2024
Journal: Cell Death Dis
Title: Selective deletion of E3 ubiquitin ligase FBW7 in VE-cadherin-positive cells instigates diffuse large B-cell lymphoma in mice in vivo.
Volume: 15
Issue: 3
Pages: 212
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12354302 | J:79007
First Author: Li J
Year: 2002
Journal: J Neurochem
Title: SEL-10 interacts with presenilin 1, facilitates its ubiquitination, and alters A-beta peptide production.
Volume: 82
Issue: 6
Pages: 1540-8
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23507969 | J:219052
First Author: Wang R
Year: 2013
Journal: Cell Res
Title: FBW7 regulates endothelial functions by targeting KLF2 for ubiquitination and degradation.
Volume: 23
Issue: 6
Pages: 803-19
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31445163 | J:282574
 
First Author: Shen Y
Year: 2019
Journal: Neurobiol Dis
Title: Smooth muscle cell-specific knockout of FBW7 exacerbates intracranial atherosclerotic stenosis.
Volume: 132
Pages: 104584
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34351636 | J:344064
First Author: Feng C
Year: 2021
Journal: Immunology
Title: Critical roles of the E3 ubiquitin ligase FBW7 in B-cell response and the pathogenesis of experimental autoimmune arthritis.
Volume: 164
Issue: 3
Pages: 617-636
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32853822 | J:314336
 
First Author: Wang C
Year: 2020
Journal: Redox Biol
Title: Myeloid FBW7 deficiency disrupts redox homeostasis and aggravates dietary-induced insulin resistance.
Volume: 37
Pages: 101688
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28036276 | J:325937
First Author: Takada M
Year: 2017
Journal: Oncotarget
Title: EglN2 contributes to triple negative breast tumorigenesis by functioning as a substrate for the FBW7 tumor suppressor.
Volume: 8
Issue: 4
Pages: 6787-6795
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21953459 | J:252001
First Author: Biswas M
Year: 2011
Journal: J Biol Chem
Title: The Fbw7 tumor suppressor regulates nuclear factor E2-related factor 1 transcription factor turnover through proteasome-mediated proteolysis.
Volume: 286
Issue: 45
Pages: 39282-9
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25437563 | J:218602
First Author: Schülein-Völk C
Year: 2014
Journal: Cell Rep
Title: Dual regulation of Fbw7 function and oncogenic transformation by Usp28.
Volume: 9
Issue: 3
Pages: 1099-109
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21368833 | J:170813
First Author: Inuzuka H
Year: 2011
Journal: Nature
Title: SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
Volume: 471
Issue: 7336
Pages: 104-9
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25105579 | J:215154
First Author: Sancho R
Year: 2014
Journal: Cell Stem Cell
Title: Loss of Fbw7 reprograms adult pancreatic ductal cells into α, δ, and β cells.
Volume: 15
Issue: 2
Pages: 139-53
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Publication
32931083 | J:347375
First Author: Hoshikawa S
Year: 2020
Journal: FASEB J
Title: Phosphorylation-dependent osterix degradation negatively regulates osteoblast differentiation.
Volume: 34
Issue: 11
Pages: 14930-14945
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22608923 | J:188019
First Author: Min SH
Year: 2012
Journal: Mol Cell
Title: Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomerase.
Volume: 46
Issue: 6
Pages: 771-83
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29149593 | J:251942
First Author: Fukushima H
Year: 2017
Journal: Mol Cell
Title: NOTCH2 Hajdu-Cheney Mutations Escape SCFFBW7-Dependent Proteolysis to Promote Osteoporosis.
Volume: 68
Issue: 4
Pages: 645-658.e5
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Publication
21147854 | J:182894
First Author: Mo JS
Year: 2011
Journal: J Cell Sci
Title: Serum- and glucocorticoid-inducible kinase 1 (SGK1) controls Notch1 signaling by downregulation of protein stability through Fbw7 ubiquitin ligase.
Volume: 124
Issue: Pt 1
Pages: 100-12
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Publication
23575666 | J:325933
 
First Author: Balamurugan K
Year: 2013
Journal: Nat Commun
Title: FBXW7α attenuates inflammatory signalling by downregulating C/EBPδ and its target gene Tlr4.
Volume: 4
Pages: 1662
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22473991 | J:185723
First Author: Grim JE
Year: 2012
Journal: Mol Cell Biol
Title: Fbw7 and p53 cooperatively suppress advanced and chromosomally unstable intestinal cancer.
Volume: 32
Issue: 11
Pages: 2160-7
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Publication
32005754 | J:287113
First Author: Ramezani-Rad P
Year: 2020
Journal: J Immunol
Title: E3 Ubiquitin Ligase Fbw7 Regulates the Survival of Mature B Cells.
Volume: 204
Issue: 6
Pages: 1535-1542
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Publication
24752894 | J:223694
First Author: Sun Y
Year: 2014
Journal: Mol Cell Biol
Title: The canonical wnt signal restricts the glycogen synthase kinase 3/fbw7-dependent ubiquitination and degradation of eya1 phosphatase.
Volume: 34
Issue: 13
Pages: 2409-17
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Publication
23873023 | J:212621
First Author: Xu Y
Year: 2014
Journal: Oncogene
Title: Fbw7-dependent cyclin E regulation ensures terminal maturation of bone marrow erythroid cells by restraining oxidative metabolism.
Volume: 33
Issue: 24
Pages: 3161-71
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