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Search results 1 to 89 out of 89 for Flcn

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Category: Publication
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Type Details Score
Publication
31272105 | J:298784
First Author: Kennedy JC
Year: 2019
Journal: Hum Mol Genet
Title: Loss of FLCN inhibits canonical WNT signaling via TFE3.
Volume: 28
Issue: 19
Pages: 3270-3281
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Publication
31806376 | J:294581
First Author: Isono Y
Year: 2020
Journal: Biochem Biophys Res Commun
Title: FLCN alteration drives metabolic reprogramming towards nucleotide synthesis and cyst formation in salivary gland.
Volume: 522
Issue: 4
Pages: 931-938
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Publication
26083655 | J:273482
First Author: Chen J
Year: 2015
Journal: Kidney Int
Title: Disruption of tubular Flcn expression as a mouse model for renal tumor induction.
Volume: 88
Issue: 5
Pages: 1057-69
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Publication
27151976 | J:232555
First Author: Yan M
Year: 2016
Journal: Genes Dev
Title: Chronic AMPK activation via loss of FLCN induces functional beige adipose tissue through PGC-1α/ERRα.
Volume: 30
Issue: 9
Pages: 1034-46
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Publication
26439621 | J:228895
First Author: Possik E
Year: 2015
Journal: PLoS Genet
Title: FLCN and AMPK Confer Resistance to Hyperosmotic Stress via Remodeling of Glycogen Stores.
Volume: 11
Issue: 10
Pages: e1005520
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Publication
27913603 | J:285017
First Author: Wada S
Year: 2016
Journal: Genes Dev
Title: The tumor suppressor FLCN mediates an alternate mTOR pathway to regulate browning of adipose tissue.
Volume: 30
Issue: 22
Pages: 2551-2564
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Publication
21209915 | J:196261
First Author: Hong SB
Year: 2010
Journal: PLoS One
Title: Inactivation of the FLCN tumor suppressor gene induces TFE3 transcriptional activity by increasing its nuclear localization.
Volume: 5
Issue: 12
Pages: e15793
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Publication
33298956 | J:300986
First Author: Tai-Nagara I
Year: 2020
Journal: Nat Commun
Title: Blood and lymphatic systems are segregated by the FLCN tumor suppressor.
Volume: 11
Issue: 1
Pages: 6314
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Publication
18974783 | J:143922
First Author: Chen J
Year: 2008
Journal: PLoS One
Title: Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia.
Volume: 3
Issue: 10
Pages: e3581
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Publication
34711912 | J:312944
First Author: Paquette M
Year: 2021
Journal: Sci Rep
Title: Loss of hepatic Flcn protects against fibrosis and inflammation by activating autophagy pathways.
Volume: 11
Issue: 1
Pages: 21268
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Publication
24726356 | J:211817
First Author: Goncharova EA
Year: 2014
Journal: Cell Rep
Title: Folliculin controls lung alveolar enlargement and epithelial cell survival through E-cadherin, LKB1, and AMPK.
Volume: 7
Issue: 2
Pages: 412-23
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Publication
30917316 | J:290692
First Author: El-Houjeiri L
Year: 2019
Journal: Cell Rep
Title: The Transcription Factors TFEB and TFE3 Link the FLCN-AMPK Signaling Axis to Innate Immune Response and Pathogen Resistance.
Volume: 26
Issue: 13
Pages: 3613-3628.e6
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Publication
32049013 | J:287690
First Author: Endoh M
Year: 2020
Journal: Cell Rep
Title: A FLCN-TFE3 Feedback Loop Prevents Excessive Glycogenesis and Phagocyte Activation by Regulating Lysosome Activity.
Volume: 30
Issue: 6
Pages: 1823-1834.e5
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Publication
26418749 | J:309334
First Author: Wu M
Year: 2015
Journal: Oncotarget
Title: Flcn-deficient renal cells are tumorigenic and sensitive to mTOR suppression.
Volume: 6
Issue: 32
Pages: 32761-73
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Publication
28656962 | J:250225
 
First Author: Laviolette LA
Year: 2017
Journal: Nat Commun
Title: Negative regulation of EGFR signalling by the human folliculin tumour suppressor protein.
Volume: 8
Pages: 15866
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Publication
24081491 | J:201807
First Author: Petit CS
Year: 2013
Journal: J Cell Biol
Title: Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases.
Volume: 202
Issue: 7
Pages: 1107-22
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Publication
24762438 | J:212826
First Author: Yan M
Year: 2014
Journal: J Clin Invest
Title: The tumor suppressor folliculin regulates AMPK-dependent metabolic transformation.
Volume: 124
Issue: 6
Pages: 2640-50
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Publication
28007907 | J:241439
First Author: Hasumi H
Year: 2017
Journal: Hum Mol Genet
Title: H255Y and K508R missense mutations in tumour suppressor folliculin (FLCN) promote kidney cell proliferation.
Volume: 26
Issue: 2
Pages: 354-366
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Publication
39406246 | J:358114
First Author: Raynor JL
Year: 2024
Journal: Immunity
Title: CRISPR screens unveil nutrient-dependent lysosomal and mitochondrial nodes impacting intestinal tissue-resident memory CD8(+) T cell formation.
Volume: 57
Issue: 11
Pages: 2597-2614.e13
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Publication
30843872 | J:285885
   
First Author: Li J
Year: 2019
Journal: JCI Insight
Title: Myeloid Folliculin balances mTOR activation to maintain innate immunity homeostasis.
Volume: 5
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Publication
23139756 | J:195594
First Author: Medvetz DA
Year: 2012
Journal: PLoS One
Title: Folliculin, the product of the Birt-Hogg-Dube tumor suppressor gene, interacts with the adherens junction protein p0071 to regulate cell-cell adhesion.
Volume: 7
Issue: 11
Pages: e47842
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Publication
22965878 | J:196228
First Author: Nahorski MS
Year: 2012
Journal: Hum Mol Genet
Title: Folliculin interacts with p0071 (plakophilin-4) and deficiency is associated with disordered RhoA signalling, epithelial polarization and cytokinesis.
Volume: 21
Issue: 24
Pages: 5268-79
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Publication
23582324 | J:201276
First Author: Betschinger J
Year: 2013
Journal: Cell
Title: Exit from pluripotency is gated by intracellular redistribution of the bHLH transcription factor Tfe3.
Volume: 153
Issue: 2
Pages: 335-47
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Publication
27095138 | J:235170
First Author: Baba M
Year: 2016
Journal: Stem Cells
Title: Loss of Folliculin Disrupts Hematopoietic Stem Cell Quiescence and Homeostasis Resulting in Bone Marrow Failure.
Volume: 34
Issue: 4
Pages: 1068-82
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Publication
24908670 | J:214735
First Author: Hasumi Y
Year: 2014
Journal: Hum Mol Genet
Title: Folliculin (Flcn) inactivation leads to murine cardiac hypertrophy through mTORC1 deregulation.
Volume: 23
Issue: 21
Pages: 5706-19
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Publication
22709692 | J:189078
First Author: Baba M
Year: 2012
Journal: Blood
Title: The folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dubé syndrome is required for murine B-cell development.
Volume: 120
Issue: 6
Pages: 1254-61
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Publication
36987696 | J:335554
First Author: Di Malta C
Year: 2023
Journal: EMBO Mol Med
Title: TFEB and TFE3 drive kidney cystogenesis and tumorigenesis.
Volume: 15
Issue: 5
Pages: e16877
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Publication
25775561 | J:220672
First Author: Hasumi H
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Folliculin-interacting proteins Fnip1 and Fnip2 play critical roles in kidney tumor suppression in cooperation with Flcn.
Volume: 112
Issue: 13
Pages: E1624-31
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Publication
28363698 | J:255912
First Author: Zhou Q
Year: 2017
Journal: Biochim Biophys Acta
Title: Dihydromyricetin prevents obesity-induced slow-twitch-fiber reduction partially via FLCN/FNIP1/AMPK pathway.
Volume: 1863
Issue: 6
Pages: 1282-1291
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Publication
23150719 | J:192024
First Author: Hasumi H
Year: 2012
Journal: J Natl Cancer Inst
Title: Regulation of mitochondrial oxidative metabolism by tumor suppressor FLCN.
Volume: 104
Issue: 22
Pages: 1750-64
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Publication
37407815 | J:342910
First Author: Guo C
Year: 2023
Journal: Nature
Title: SLC38A2 and glutamine signalling in cDC1s dictate anti-tumour immunity.
Volume: 620
Issue: 7972
Pages: 200-208
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Publication
19843504 | J:161878
First Author: Hudon V
Year: 2010
Journal: J Med Genet
Title: Renal tumour suppressor function of the Birt-Hogg-Dubé syndrome gene product folliculin.
Volume: 47
Issue: 3
Pages: 182-9
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Publication
37380769 | J:338195
First Author: Zhang X
Year: 2023
Journal: Nature
Title: Reprogramming tumour-associated macrophages to outcompete cancer cells.
Volume: 619
Issue: 7970
Pages: 616-623
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Publication
19234517 | J:147582
First Author: Hartman TR
Year: 2009
Journal: Oncogene
Title: The role of the Birt-Hogg-Dubé protein in mTOR activation and renal tumorigenesis.
Volume: 28
Issue: 13
Pages: 1594-604
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Publication
21258407 | J:173708
First Author: Cash TP
Year: 2011
Journal: Oncogene
Title: Loss of the Birt-Hogg-Dubé tumor suppressor results in apoptotic resistance due to aberrant TGFβ-mediated transcription.
Volume: 30
Issue: 22
Pages: 2534-46
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Publication
18182616 | J:130978
First Author: Baba M
Year: 2008
Journal: J Natl Cancer Inst
Title: Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys.
Volume: 100
Issue: 2
Pages: 140-54
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Publication
32612235 | J:296987
First Author: Napolitano G
Year: 2020
Journal: Nature
Title: A substrate-specific mTORC1 pathway underlies Birt-Hogg-Dubé syndrome.
Volume: 585
Issue: 7826
Pages: 597-602
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Publication
35420934 | J:323823
First Author: Gosis BS
Year: 2022
Journal: Science
Title: Inhibition of nonalcoholic fatty liver disease in mice by selective inhibition of mTORC1.
Volume: 376
Issue: 6590
Pages: eabf8271
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Publication
36794754 | J:350273
First Author: Shillingford JM
Year: 2023
Journal: Am J Physiol Renal Physiol
Title: Functional TFEB activation characterizes multiple models of renal cystic disease and loss of polycystin-1.
Volume: 324
Issue: 4
Pages: F404-F422
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Publication
19850877 | J:154667
First Author: Hasumi Y
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2.
Volume: 106
Issue: 44
Pages: 18722-7
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Publication
26831464 | J:356935
 
First Author: Filipova D
Year: 2016
Journal: Sci Rep
Title: Gene profiling of embryonic skeletal muscle lacking type I ryanodine receptor Ca(2+) release channel.
Volume: 6
Pages: 20050
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Publication
29688375 | J:250512
   
First Author: Li J
Year: 2018
Journal: Database (Oxford)
Title: CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.
Volume: 2018
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
15741177 | J:126097
First Author: Cobellis G
Year: 2005
Journal: Nucleic Acids Res
Title: Tagging genes with cassette-exchange sites.
Volume: 33
Issue: 4
Pages: e44
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
33609526 | J:304807
   
First Author: Wang X
Year: 2021
Journal: J Biol Chem
Title: FLCN regulates transferrin receptor 1 transport and iron homeostasis.
Pages: 100426
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Publication
18403135 | J:137481
First Author: Hasumi H
Year: 2008
Journal: Gene
Title: Identification and characterization of a novel folliculin-interacting protein FNIP2.
Volume: 415
Issue: 1-2
Pages: 60-7
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Publication
12606363 | J:83525
First Author: Brown PR
Year: 2003
Journal: Biol Reprod
Title: A-kinase anchoring protein 4 binding proteins in the fibrous sheath of the sperm flagellum.
Volume: 68
Issue: 6
Pages: 2241-8
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Publication
36357396 | J:331095
First Author: Asrani K
Year: 2022
Journal: Nat Commun
Title: An mTORC1-mediated negative feedback loop constrains amino acid-induced FLCN-Rag activation in renal cells with TSC2 loss.
Volume: 13
Issue: 1
Pages: 6808
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Publication
30733432 | J:273671
First Author: Mathieu J
Year: 2019
Journal: Nat Commun
Title: Folliculin regulates mTORC1/2 and WNT pathways in early human pluripotency.
Volume: 10
Issue: 1
Pages: 632
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Publication
24763318 | J:213235
First Author: Possik E
Year: 2014
Journal: PLoS Genet
Title: Folliculin regulates ampk-dependent autophagy and metabolic stress survival.
Volume: 10
Issue: 4
Pages: e1004273
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Publication
30917721 | J:313276
First Author: Fernandez-Mosquera L
Year: 2019
Journal: Autophagy
Title: Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis.
Volume: 15
Issue: 9
Pages: 1572-1591
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Publication
22977732 | -
First Author: Nookala RK
Year: 2012
Journal: Open Biol
Title: Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer.
Volume: 2
Issue: 8
Pages: 120071
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Publication
22065758 | -
First Author: Wu X
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Insights regarding guanine nucleotide exchange from the structure of a DENN-domain protein complexed with its Rab GTPase substrate.
Volume: 108
Issue: 46
Pages: 18672-7
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Publication
23248642 | -
 
First Author: Zhang D
Year: 2012
Journal: Front Genet
Title: Discovery of Novel DENN Proteins: Implications for the Evolution of Eukaryotic Intracellular Membrane Structures and Human Disease.
Volume: 3
Pages: 283
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Publication
11563850 | -
First Author: Levivier E
Year: 2001
Journal: Biochem Biophys Res Commun
Title: uDENN, DENN, and dDENN: indissociable domains in Rab and MAP kinases signaling pathways.
Volume: 287
Issue: 3
Pages: 688-95
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Publication
12906859 | -
First Author: Semova N
Year: 2003
Journal: Genomics
Title: Molecular cloning, structural analysis, and expression of a human IRLB, MYC promoter-binding protein: new DENN domain-containing protein family emerges.
Volume: 82
Issue: 3
Pages: 343-54
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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