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Search results 1 to 100 out of 119 for Gpbar1

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Category: Publication
Type Details Score
Publication
First Author: Vassileva G
Year: 2006
Journal: Biochem J
Title: Targeted deletion of Gpbar1 protects mice from cholesterol gallstone formation.
Volume: 398
Issue: 3
Pages: 423-30
Publication
First Author: Lund ML
Year: 2020
Journal: Diabetes
Title: L-Cell Differentiation Is Induced by Bile Acids Through GPBAR1 and Paracrine GLP-1 and Serotonin Signaling.
Volume: 69
Issue: 4
Pages: 614-623
Publication
First Author: Vassileva G
Year: 2010
Journal: J Endocrinol
Title: Gender-dependent effect of Gpbar1 genetic deletion on the metabolic profiles of diet-induced obese mice.
Volume: 205
Issue: 3
Pages: 225-32
Publication
First Author: Carino A
Year: 2021
Journal: FASEB J
Title: The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy.
Volume: 35
Issue: 1
Pages: e21271
Publication
First Author: Carino A
Year: 2017
Journal: Sci Rep
Title: Gpbar1 agonism promotes a Pgc-1α-dependent browning of white adipose tissue and energy expenditure and reverses diet-induced steatohepatitis in mice.
Volume: 7
Issue: 1
Pages: 13689
Publication
First Author: Lavoie B
Year: 2010
Journal: J Physiol
Title: Hydrophobic bile salts inhibit gallbladder smooth muscle function via stimulation of GPBAR1 receptors and activation of KATP channels.
Volume: 588
Issue: Pt 17
Pages: 3295-305
Publication
First Author: Carino A
Year: 2019
Journal: FASEB J
Title: Agonism for the bile acid receptor GPBAR1 reverses liver and vascular damage in a mouse model of steatohepatitis.
Volume: 33
Issue: 2
Pages: 2809-2822
Publication
First Author: Biagioli M
Year: 2019
Journal: Cell Mol Gastroenterol Hepatol
Title: GPBAR1 Functions as Gatekeeper for Liver NKT Cells and provides Counterregulatory Signals in Mouse Models of Immune-Mediated Hepatitis.
Volume: 8
Issue: 3
Pages: 447-473
Publication
First Author: Biagioli M
Year: 2017
Journal: J Immunol
Title: The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis.
Volume: 199
Issue: 2
Pages: 718-733
Publication
First Author: Biagioli M
Year: 2020
Journal: J Immunol
Title: The Bile Acid Receptor GPBAR1 Modulates CCL2/CCR2 Signaling at the Liver Sinusoidal/Macrophage Interface and Reverses Acetaminophen-Induced Liver Toxicity.
Volume: 204
Issue: 9
Pages: 2535-2551
Publication  
First Author: Li W
Year: 2023
Journal: Phytomedicine
Title: Red ginseng extracts ameliorate high-fat diet-induced obesity and insulin resistance by activating the intestinal TGR5-mediated bile acids signaling pathway.
Volume: 119
Pages: 154982
Publication
First Author: Alemi F
Year: 2013
Journal: J Clin Invest
Title: The TGR5 receptor mediates bile acid-induced itch and analgesia.
Volume: 123
Issue: 4
Pages: 1513-30
Publication
First Author: Thomas C
Year: 2009
Journal: Cell Metab
Title: TGR5-mediated bile acid sensing controls glucose homeostasis.
Volume: 10
Issue: 3
Pages: 167-77
Publication  
First Author: Klindt C
Year: 2019
Journal: Cells
Title: The G Protein-Coupled Bile Acid Receptor TGR5 (Gpbar1) Modulates Endothelin-1 Signaling in Liver.
Volume: 8
Issue: 11
Publication
First Author: Maruyama T
Year: 2006
Journal: J Endocrinol
Title: Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice.
Volume: 191
Issue: 1
Pages: 197-205
Publication  
First Author: Biagioli M
Year: 2020
Journal: Biochem Pharmacol
Title: Identification of cysteinyl-leukotriene-receptor 1 antagonists as ligands for the bile acid receptor GPBAR1.
Volume: 177
Pages: 113987
Publication
First Author: Wu Q
Year: 2021
Journal: Cell Metab
Title: Intestinal hypoxia-inducible factor 2α regulates lactate levels to shape the gut microbiome and alter thermogenesis.
Volume: 33
Issue: 10
Pages: 1988-2003.e7
Publication  
First Author: Castro J
Year: 2019
Journal: JCI Insight
Title: Activation of pruritogenic TGR5, MrgprA3, and MrgprC11 on colon-innervating afferents induces visceral hypersensitivity.
Volume: 4
Issue: 20
Publication
First Author: Ibrahim E
Year: 2018
Journal: Sci Rep
Title: Bile acids and their respective conjugates elicit different responses in neonatal cardiomyocytes: role of Gi protein, muscarinic receptors and TGR5.
Volume: 8
Issue: 1
Pages: 7110
Publication
First Author: Renga B
Year: 2015
Journal: Am J Physiol Heart Circ Physiol
Title: Cystathionine γ-lyase, a H2S-generating enzyme, is a GPBAR1-regulated gene and contributes to vasodilation caused by secondary bile acids.
Volume: 309
Issue: 1
Pages: H114-26
Publication
First Author: Caldwell A
Year: 2022
Journal: Sci Rep
Title: TGR5 agonists induce peripheral and central hypersensitivity to bladder distension.
Volume: 12
Issue: 1
Pages: 9920
Publication
First Author: Maruyama T
Year: 2002
Journal: Biochem Biophys Res Commun
Title: Identification of membrane-type receptor for bile acids (M-BAR).
Volume: 298
Issue: 5
Pages: 714-9
Publication
First Author: Kawamata Y
Year: 2003
Journal: J Biol Chem
Title: A G protein-coupled receptor responsive to bile acids.
Volume: 278
Issue: 11
Pages: 9435-40
Publication  
First Author: Holter MM
Year: 2020
Journal: Nutrients
Title: Compound 18 Improves Glucose Tolerance in a Hepatocyte TGR5-dependent Manner in Mice.
Volume: 12
Issue: 7
Publication
First Author: Péan N
Year: 2013
Journal: Hepatology
Title: The receptor TGR5 protects the liver from bile acid overload during liver regeneration in mice.
Volume: 58
Issue: 4
Pages: 1451-60
Publication
First Author: Cipriani S
Year: 2011
Journal: PLoS One
Title: The bile acid receptor GPBAR-1 (TGR5) modulates integrity of intestinal barrier and immune response to experimental colitis.
Volume: 6
Issue: 10
Pages: e25637
Publication
First Author: Willis KA
Year: 2020
Journal: Am J Physiol Gastrointest Liver Physiol
Title: TGR5 signaling mitigates parenteral nutrition-associated liver disease.
Volume: 318
Issue: 2
Pages: G322-G335
Publication
First Author: Reddy IA
Year: 2018
Journal: PLoS Biol
Title: Bile diversion, a bariatric surgery, and bile acid signaling reduce central cocaine reward.
Volume: 16
Issue: 7
Pages: e2006682
Publication
First Author: Syring KE
Year: 2019
Journal: Am J Physiol Endocrinol Metab
Title: Systemic bile acids induce insulin resistance in a TGR5-independent manner.
Volume: 316
Issue: 5
Pages: E782-E793
Publication  
First Author: Bensalem A
Year: 2020
Journal: J Nutr Biochem
Title: Bile acid receptor TGR5 is critically involved in preference for dietary lipids and obesity.
Volume: 76
Pages: 108298
Publication
First Author: Donepudi AC
Year: 2017
Journal: Hepatology
Title: G-protein-coupled bile acid receptor plays a key role in bile acid metabolism and fasting-induced hepatic steatosis in mice.
Volume: 65
Issue: 3
Pages: 813-827
Publication
First Author: Velazquez-Villegas LA
Year: 2018
Journal: Nat Commun
Title: TGR5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue.
Volume: 9
Issue: 1
Pages: 245
Publication
First Author: Lajczak NK
Year: 2017
Journal: FASEB J
Title: Bile acids deoxycholic acid and ursodeoxycholic acid differentially regulate human β-defensin-1 and -2 secretion by colonic epithelial cells.
Volume: 31
Issue: 9
Pages: 3848-3857
Publication
First Author: Abrigo J
Year: 2021
Journal: J Cell Physiol
Title: Cholic acid and deoxycholic acid induce skeletal muscle atrophy through a mechanism dependent on TGR5 receptor.
Volume: 236
Issue: 1
Pages: 260-272
Publication  
First Author: Abrigo J
Year: 2020
Journal: Int J Mol Sci
Title: Sarcopenia Induced by Chronic Liver Disease in Mice Requires the Expression of the Bile Acids Membrane Receptor TGR5.
Volume: 21
Issue: 21
Publication
First Author: Cortés V
Year: 2015
Journal: PLoS One
Title: Metabolic effects of cholecystectomy: gallbladder ablation increases basal metabolic rate through G-protein coupled bile acid receptor Gpbar1-dependent mechanisms in mice.
Volume: 10
Issue: 3
Pages: e0118478
Publication
First Author: Baptissart M
Year: 2014
Journal: Hepatology
Title: Bile acids alter male fertility through G-protein-coupled bile acid receptor 1 signaling pathways in mice.
Volume: 60
Issue: 3
Pages: 1054-65
Publication
First Author: Rao J
Year: 2020
Journal: Int Immunol
Title: Deficiency of TGR5 exacerbates immune-mediated cholestatic hepatic injury by stabilizing the β-catenin destruction complex.
Volume: 32
Issue: 5
Pages: 321-334
Publication  
First Author: Sun L
Year: 2024
Journal: Int Immunopharmacol
Title: Targeting TGR5 to mitigate liver fibrosis: Inhibition of hepatic stellate cell activation through modulation of mitochondrial fission.
Volume: 140
Pages: 112831
Publication
First Author: McMillin M
Year: 2015
Journal: J Neurochem
Title: TGR5 signaling reduces neuroinflammation during hepatic encephalopathy.
Volume: 135
Issue: 3
Pages: 565-76
Publication
First Author: Li ZY
Year: 2019
Journal: Mol Med Rep
Title: Activation of TGR5 alleviates inflammation in rheumatoid arthritis peripheral blood mononuclear cells and in mice with collagen II‑induced arthritis.
Volume: 20
Issue: 5
Pages: 4540-4550
Publication
First Author: Li S
Year: 2018
Journal: J Am Soc Nephrol
Title: Bile Acid G Protein-Coupled Membrane Receptor TGR5 Modulates Aquaporin 2-Mediated Water Homeostasis.
Volume: 29
Issue: 11
Pages: 2658-2670
Publication  
First Author: Wang J
Year: 2020
Journal: J Mol Cell Cardiol
Title: DCA-TGR5 signaling activation alleviates inflammatory response and improves cardiac function in myocardial infarction.
Volume: 151
Pages: 3-14
Publication
First Author: Han M
Year: 2021
Journal: Am J Physiol Renal Physiol
Title: Activation of TGR5 restores AQP2 expression via the HIF pathway in renal ischemia-reperfusion injury.
Volume: 320
Issue: 3
Pages: F308-F321
Publication
First Author: Wang H
Year: 2021
Journal: Biol Psychiatry
Title: Takeda G Protein-Coupled Receptor 5 Modulates Depression-like Behaviors via Hippocampal CA3 Pyramidal Neurons Afferent to Dorsolateral Septum.
Volume: 89
Issue: 11
Pages: 1084-1095
Publication  
First Author: Sasaki T
Year: 2021
Journal: J Biol Chem
Title: Muscle-specific TGR5 overexpression improves glucose clearance in glucose-intolerant mice.
Volume: 296
Pages: 100131
Publication  
First Author: Xiong Q
Year: 2018
Journal: Front Immunol
Title: Metabolite-Sensing G Protein Coupled Receptor TGR5 Protects Host From Viral Infection Through Amplifying Type I Interferon Responses.
Volume: 9
Pages: 2289
Publication
First Author: Li C
Year: 2024
Journal: Sci Adv
Title: TGR5 deficiency in excitatory neurons ameliorates Alzheimer's pathology by regulating APP processing.
Volume: 10
Issue: 26
Pages: eado1855
Publication
First Author: Perino A
Year: 2021
Journal: Nat Metab
Title: Central anorexigenic actions of bile acids are mediated by TGR5.
Volume: 3
Issue: 5
Pages: 595-603
Publication
First Author: Merlen G
Year: 2020
Journal: Gut
Title: TGR5-dependent hepatoprotection through the regulation of biliary epithelium barrier function.
Volume: 69
Issue: 1
Pages: 146-157
Publication  
First Author: Somm E
Year: 2017
Journal: JCI Insight
Title: β-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue.
Volume: 2
Issue: 8
Publication
First Author: Sorrentino G
Year: 2020
Journal: Gastroenterology
Title: Bile Acids Signal via TGR5 to Activate Intestinal Stem Cells and Epithelial Regeneration.
Volume: 159
Issue: 3
Pages: 956-968.e8
Publication
First Author: Sasaki T
Year: 2018
Journal: J Biol Chem
Title: The exercise-inducible bile acid receptor Tgr5 improves skeletal muscle function in mice.
Volume: 293
Issue: 26
Pages: 10322-10332
Publication  
First Author: Harach T
Year: 2012
Journal: Sci Rep
Title: TGR5 potentiates GLP-1 secretion in response to anionic exchange resins.
Volume: 2
Pages: 430
Publication
First Author: Rajagopal S
Year: 2013
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Activation of G protein-coupled bile acid receptor, TGR5, induces smooth muscle relaxation via both Epac- and PKA-mediated inhibition of RhoA/Rho kinase pathway.
Volume: 304
Issue: 5
Pages: G527-35
Publication    
First Author: Donkers JM
Year: 2019
Journal: JCI Insight
Title: NTCP deficiency in mice protects against obesity and hepatosteatosis.
Volume: 5
Publication
First Author: Lieu T
Year: 2014
Journal: Gastroenterology
Title: The bile acid receptor TGR5 activates the TRPA1 channel to induce itch in mice.
Volume: 147
Issue: 6
Pages: 1417-28
Publication  
First Author: Chang S
Year: 2018
Journal: Front Immunol
Title: Taurodeoxycholate Increases the Number of Myeloid-Derived Suppressor Cells That Ameliorate Sepsis in Mice.
Volume: 9
Pages: 1984
Publication
First Author: Pols TW
Year: 2011
Journal: Cell Metab
Title: TGR5 activation inhibits atherosclerosis by reducing macrophage inflammation and lipid loading.
Volume: 14
Issue: 6
Pages: 747-57
Publication
First Author: Wang XX
Year: 2022
Journal: J Biol Chem
Title: The role of FXR and TGR5 in reversing and preventing progression of Western diet-induced hepatic steatosis, inflammation, and fibrosis in mice.
Volume: 298
Issue: 11
Pages: 102530
Publication
First Author: Pathak P
Year: 2017
Journal: J Biol Chem
Title: Farnesoid X receptor induces Takeda G-protein receptor 5 cross-talk to regulate bile acid synthesis and hepatic metabolism.
Volume: 292
Issue: 26
Pages: 11055-11069
Publication
First Author: Fang S
Year: 2015
Journal: Nat Med
Title: Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance.
Volume: 21
Issue: 2
Pages: 159-65
Publication
First Author: Wang Q
Year: 2023
Journal: Gut Microbes
Title: Gut microbiota regulates postprandial GLP-1 response via ileal bile acid-TGR5 signaling.
Volume: 15
Issue: 2
Pages: 2274124
Publication
First Author: Chen X
Year: 2015
Journal: PLoS One
Title: Identification of miR-26a as a target gene of bile acid receptor GPBAR-1/TGR5.
Volume: 10
Issue: 6
Pages: e0131294
Publication
First Author: Lou G
Year: 2014
Journal: PLoS One
Title: GPBAR1/TGR5 mediates bile acid-induced cytokine expression in murine Kupffer cells.
Volume: 9
Issue: 4
Pages: e93567
Publication  
First Author: Islam J
Year: 2022
Journal: Front Immunol
Title: GPCR19 Regulates P2X7R-Mediated NLRP3 Inflammasomal Activation of Microglia by Amyloid β in a Mouse Model of Alzheimer's Disease.
Volume: 13
Pages: 766919
Publication
First Author: Bellafante E
Year: 2020
Journal: Sci Rep
Title: Maternal glucose homeostasis is impaired in mouse models of gestational cholestasis.
Volume: 10
Issue: 1
Pages: 11523
Publication
First Author: Li Z
Year: 2019
Journal: J Bone Miner Res
Title: Dual Targeting of Bile Acid Receptor-1 (TGR5) and Farnesoid X Receptor (FXR) Prevents Estrogen-Dependent Bone Loss in Mice.
Volume: 34
Issue: 4
Pages: 765-776
Publication
First Author: Moepps B
Year: 2006
Journal: Mol Immunol
Title: A homolog of the human chemokine receptor CXCR1 is expressed in the mouse.
Volume: 43
Issue: 7
Pages: 897-914
Publication
First Author: Kumar DP
Year: 2016
Journal: J Biol Chem
Title: Activation of Transmembrane Bile Acid Receptor TGR5 Modulates Pancreatic Islet α Cells to Promote Glucose Homeostasis.
Volume: 291
Issue: 13
Pages: 6626-40
Publication
First Author: Wang XX
Year: 2017
Journal: J Biol Chem
Title: A dual agonist of farnesoid X receptor (FXR) and the G protein-coupled receptor TGR5, INT-767, reverses age-related kidney disease in mice.
Volume: 292
Issue: 29
Pages: 12018-12024
Publication
First Author: Peiper AM
Year: 2024
Journal: Cell Host Microbe
Title: Metabolic immaturity and breastmilk bile acid metabolites are central determinants of heightened newborn vulnerability to norovirus diarrhea.
Volume: 32
Issue: 9
Pages: 1488-1501.e5
Publication
First Author: Castellanos-Jankiewicz A
Year: 2021
Journal: Cell Metab
Title: Hypothalamic bile acid-TGR5 signaling protects from obesity.
Volume: 33
Issue: 7
Pages: 1483-1492.e10
Publication
First Author: Perino A
Year: 2014
Journal: J Clin Invest
Title: TGR5 reduces macrophage migration through mTOR-induced C/EBPβ differential translation.
Volume: 124
Issue: 12
Pages: 5424-36
Publication      
First Author: Li XY
Year: 2024
Journal: Neuron
Title: TGR5-mediated lateral hypothalamus-dCA3-dorsolateral septum circuit regulates depressive-like behavior in male mice.
Publication
First Author: Wang XX
Year: 2018
Journal: J Am Soc Nephrol
Title: FXR/TGR5 Dual Agonist Prevents Progression of Nephropathy in Diabetes and Obesity.
Volume: 29
Issue: 1
Pages: 118-137
Publication  
First Author: Trabelsi MS
Year: 2015
Journal: Nat Commun
Title: Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cells.
Volume: 6
Pages: 7629
Publication
First Author: Miyazaki-Anzai S
Year: 2018
Journal: J Lipid Res
Title: Simultaneous inhibition of FXR and TGR5 exacerbates atherosclerotic formation.
Volume: 59
Issue: 9
Pages: 1709-1713
Publication
First Author: Albaugh VL
Year: 2019
Journal: Gastroenterology
Title: Role of Bile Acids and GLP-1 in Mediating the Metabolic Improvements of Bariatric Surgery.
Volume: 156
Issue: 4
Pages: 1041-1051.e4
Publication
First Author: Jain U
Year: 2018
Journal: Cell Host Microbe
Title: Temporal Regulation of the Bacterial Metabolite Deoxycholate during Colonic Repair Is Critical for Crypt Regeneration.
Volume: 24
Issue: 3
Pages: 353-363.e5
Publication
First Author: Baptissart M
Year: 2016
Journal: Oncotarget
Title: Bile acid-FXRα pathways regulate male sexual maturation in mice.
Volume: 7
Issue: 15
Pages: 19468-82
Publication
First Author: Lin Z
Year: 2023
Journal: Cell Rep
Title: The degradation of TGR5 mediated by Smurf1 contributes to diabetic nephropathy.
Volume: 42
Issue: 8
Pages: 112851
Publication
First Author: Cong J
Year: 2024
Journal: Immunity
Title: Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8(+) T cell effector functions.
Volume: 57
Issue: 4
Pages: 876-889.e11
Publication
First Author: Guo C
Year: 2016
Journal: Immunity
Title: Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome.
Volume: 45
Issue: 4
Pages: 802-816
Publication
First Author: Pepe-Mooney BJ
Year: 2019
Journal: Cell Stem Cell
Title: Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration.
Volume: 25
Issue: 1
Pages: 23-38.e8
Publication
First Author: Song X
Year: 2023
Journal: Nature
Title: Gut microbial fatty acid isomerization modulates intraepithelial T cells.
Volume: 619
Issue: 7971
Pages: 837-843
Publication
First Author: Song X
Year: 2020
Journal: Nature
Title: Microbial bile acid metabolites modulate gut RORγ+ regulatory T cell homeostasis.
Volume: 577
Issue: 7790
Pages: 410-415
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
Publication        
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86