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Search results 1 to 100 out of 281 for Grem1

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Category: Publication
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Type Details Score
Publication
19401426 | J:154340
First Author: Roxburgh SA
Year: 2009
Journal: Diabetes
Title: Allelic depletion of grem1 attenuates diabetic kidney disease.
Volume: 58
Issue: 7
Pages: 1641-50
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Publication
35768509 | J:330294
First Author: Lan L
Year: 2022
Journal: Nature
Title: GREM1 is required to maintain cellular heterogeneity in pancreatic cancer.
Volume: 607
Issue: 7917
Pages: 163-168
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Publication
25419707 | J:227790
First Author: Davis H
Year: 2015
Journal: Nat Med
Title: Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche.
Volume: 21
Issue: 1
Pages: 62-70
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Publication
21281623 | J:171473
First Author: Nie X
Year: 2011
Journal: Dev Biol
Title: Six1 regulates Grem1 expression in the metanephric mesenchyme to initiate branching morphogenesis.
Volume: 352
Issue: 1
Pages: 141-51
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Publication
33819486 | J:343887
First Author: Koppens MAJ
Year: 2021
Journal: Gastroenterology
Title: Bone Morphogenetic Protein Pathway Antagonism by Grem1 Regulates Epithelial Cell Fate in Intestinal Regeneration.
Volume: 161
Issue: 1
Pages: 239-254.e9
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Publication
37034712 | J:340408
     
First Author: Ng JQ
Year: 2023
Journal: bioRxiv
Title: Loss of Grem1 -articular cartilage progenitor cells causes osteoarthritis.
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Publication
34548488 | J:312378
First Author: Malkmus J
Year: 2021
Journal: Nat Commun
Title: Spatial regulation by multiple Gremlin1 enhancers provides digit development with cis-regulatory robustness and evolutionary plasticity.
Volume: 12
Issue: 1
Pages: 5557
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Publication
24700818 | J:207959
First Author: Li Q
Year: 2014
Journal: Development
Title: A Gli silencer is required for robust repression of gremlin in the vertebrate limb bud.
Volume: 141
Issue: 9
Pages: 1906-14
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Publication
25594183 | J:219328
First Author: Worthley DL
Year: 2015
Journal: Cell
Title: Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential.
Volume: 160
Issue: 1-2
Pages: 269-84
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Publication
37907525 | J:342246
First Author: Ng JQ
Year: 2023
Journal: Nat Commun
Title: Loss of Grem1-lineage chondrogenic progenitor cells causes osteoarthritis.
Volume: 14
Issue: 1
Pages: 6909
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Publication
34184027 | J:308785
 
First Author: Ichinose M
Year: 2021
Journal: Development
Title: The BMP antagonist gremlin 1 contributes to the development of cortical excitatory neurons, motor balance and fear responses.
Volume: 148
Issue: 14
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Publication
17785465 | J:126375
First Author: Gazzerro E
Year: 2007
Journal: J Biol Chem
Title: Conditional deletion of gremlin causes a transient increase in bone formation and bone mass.
Volume: 282
Issue: 43
Pages: 31549-57
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Publication
28100499 | J:273728
First Author: Church RH
Year: 2017
Journal: Am J Physiol Renal Physiol
Title: Gremlin1 plays a key role in kidney development and renal fibrosis.
Volume: 312
Issue: 6
Pages: F1141-F1157
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Publication
37401390 | J:341245
First Author: Mthunzi L
Year: 2023
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Gremlin 1 is required for macrophage M2 polarization.
Volume: 325
Issue: 2
Pages: L270-L276
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Publication
32297672 | J:292063
First Author: Rowan SC
Year: 2020
Journal: J Pathol
Title: Gremlin 1 depletion in vivo causes severe enteropathy and bone marrow failure.
Volume: 251
Issue: 2
Pages: 117-122
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Publication
21412775 | J:274152
First Author: Canalis E
Year: 2012
Journal: J Cell Physiol
Title: Gremlin1 is required for skeletal development and postnatal skeletal homeostasis.
Volume: 227
Issue: 1
Pages: 269-77
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Publication
18545679 | J:182488
First Author: Kami D
Year: 2008
Journal: PLoS One
Title: Gremlin enhances the determined path to cardiomyogenesis.
Volume: 3
Issue: 6
Pages: e2407
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Publication
25194662 | J:216373
First Author: Siddique I
Year: 2014
Journal: Am J Pathol
Title: Gremlin promotes peritoneal membrane injury in an experimental mouse model and is associated with increased solute transport in peritoneal dialysis patients.
Volume: 184
Issue: 11
Pages: 2976-84
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Publication
27428020 | J:240356
First Author: Koli K
Year: 2016
Journal: PLoS One
Title: Gremlin-1 Overexpression in Mouse Lung Reduces Silica-Induced Lymphocyte Recruitment - A Link to Idiopathic Pulmonary Fibrosis through Negative Correlation with CXCL10 Chemokine.
Volume: 11
Issue: 7
Pages: e0159010
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20359476 | J:161416
First Author: Collette NM
Year: 2010
Journal: Dev Biol
Title: Genetic evidence that SOST inhibits WNT signaling in the limb.
Volume: 342
Issue: 2
Pages: 169-79
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Publication
29483821 | J:272082
First Author: Wang H
Year: 2018
Journal: Int J Biol Sci
Title: Disruption of Gen1 Causes Congenital Anomalies of the Kidney and Urinary Tract in Mice.
Volume: 14
Issue: 1
Pages: 10-20
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Publication
21832168 | J:182788
First Author: Myers M
Year: 2011
Journal: Biol Reprod
Title: Loss of gremlin delays primordial follicle assembly but does not affect female fertility in mice.
Volume: 85
Issue: 6
Pages: 1175-82
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Publication
1643305 | J:1741
First Author: Vogt TF
Year: 1992
Journal: Mamm Genome
Title: The same genomic region is disrupted in two transgene-induced limb deformity alleles.
Volume: 3
Issue: 8
Pages: 431-7
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Publication
- | J:22163
 
First Author: Messing A
Year: 1990
Journal: Mouse Genome
Title: Insertional mutation at the ld locus (again!) in a line of transgenic mice
Volume: 87
Pages: 107
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2997621 | J:8077
First Author: Woychik RP
Year: 1985
Journal: Nature
Title: An inherited limb deformity created by insertional mutagenesis in a transgenic mouse.
Volume: 318
Issue: 6041
Pages: 36-40
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1673046 | J:11112
First Author: Maas RL
Year: 1991
Journal: Am J Hum Genet
Title: A human gene homologous to the formin gene residing at the murine limb deformity locus: chromosomal location and RFLPs.
Volume: 48
Issue: 4
Pages: 687-95
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15201225 | J:90991
First Author: Michos O
Year: 2004
Journal: Development
Title: Gremlin-mediated BMP antagonism induces the epithelial-mesenchymal feedback signaling controlling metanephric kidney and limb organogenesis.
Volume: 131
Issue: 14
Pages: 3401-10
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19229034 | J:144933
First Author: Bénazet JD
Year: 2009
Journal: Science
Title: A self-regulatory system of interlinked signaling feedback loops controls mouse limb patterning.
Volume: 323
Issue: 5917
Pages: 1050-3
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26141517 | J:319181
First Author: Staloch D
Year: 2015
Journal: J Mol Med (Berl)
Title: Gremlin is a key pro-fibrogenic factor in chronic pancreatitis.
Volume: 93
Issue: 10
Pages: 1085-1093
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Publication
23633963 | J:200023
First Author: Farin HF
Year: 2013
Journal: PLoS Genet
Title: Tbx2 terminates shh/fgf signaling in the developing mouse limb bud by direct repression of gremlin1.
Volume: 9
Issue: 4
Pages: e1003467
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Publication
34928956 | J:317430
First Author: Sharma D
Year: 2021
Journal: PLoS Genet
Title: HES1 is a novel downstream modifier of the SHH-GLI3 Axis in the development of preaxial polydactyly.
Volume: 17
Issue: 12
Pages: e1009982
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7517224 | J:17401
First Author: Maas R
Year: 1994
Journal: Dev Dyn
Title: Deficient outgrowth of the ureteric bud underlies the renal agenesis phenotype in mice manifesting the limb deformity (ld) mutation.
Volume: 199
Issue: 3
Pages: 214-28
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25034710 | J:214075
First Author: Norrie JL
Year: 2014
Journal: Dev Biol
Title: Dynamics of BMP signaling in limb bud mesenchyme and polydactyly.
Volume: 393
Issue: 2
Pages: 270-281
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17554679 | J:123068
First Author: Pavel E
Year: 2007
Journal: Int J Dev Biol
Title: Analysis of a new allele of limb deformity (ld) reveals tissue- and age-specific transcriptional effects of the Ld Global Control Region.
Volume: 51
Issue: 4
Pages: 273-81
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Publication
16908629 | J:112237
First Author: Panman L
Year: 2006
Journal: Development
Title: Differential regulation of gene expression in the digit forming area of the mouse limb bud by SHH and gremlin 1/FGF-mediated epithelial-mesenchymal signalling.
Volume: 133
Issue: 17
Pages: 3419-28
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9234242 | J:43337
First Author: Wynshaw-Boris A
Year: 1997
Journal: Mol Med
Title: The role of a single formin isoform in the limb and renal phenotypes of limb deformity.
Volume: 3
Issue: 6
Pages: 372-84
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8792607 | J:35172
First Author: Vogt TF
Year: 1996
Journal: Dev Genet
Title: Polydactyly in the Strong's luxoid mouse is suppressed by limb deformity alleles.
Volume: 19
Issue: 1
Pages: 33-42
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17522159 | J:122530
First Author: Michos O
Year: 2007
Journal: Development
Title: Reduction of BMP4 activity by gremlin 1 enables ureteric bud outgrowth and GDNF/WNT11 feedback signalling during kidney branching morphogenesis.
Volume: 134
Issue: 13
Pages: 2397-405
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Publication
23633510 | J:197026
First Author: Sheth R
Year: 2013
Journal: Development
Title: Decoupling the function of Hox and Shh in developing limb reveals multiple inputs of Hox genes on limb growth.
Volume: 140
Issue: 10
Pages: 2130-8
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18594511 | J:138578
First Author: Verheyden JM
Year: 2008
Journal: Nature
Title: An Fgf/Gremlin inhibitory feedback loop triggers termination of limb bud outgrowth.
Volume: 454
Issue: 7204
Pages: 638-41
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Publication
- | J:210585
     
First Author: Vokes SA
Year: 2014
Journal: MGI Direct Data Submission
Title: Direct data submission for cre-inducible transgene expressing Grem1 under the control of the Rosa26 promoter
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9006074 | J:38380
First Author: Kuhlman J
Year: 1997
Journal: Development
Title: Limb deformity proteins: role in mesodermal induction of the apical ectodermal ridge.
Volume: 124
Issue: 1
Pages: 133-9
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21303853 | J:169133
First Author: Stafford DA
Year: 2011
Journal: Development
Title: Cooperative activity of noggin and gremlin 1 in axial skeleton development.
Volume: 138
Issue: 5
Pages: 1005-14
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Publication
22888807 | J:187726
 
First Author: Zuniga A
Year: 2012
Journal: BMC Dev Biol
Title: Conserved cis-regulatory regions in a large genomic landscape control SHH and BMP-regulated Gremlin1 expression in mouse limb buds.
Volume: 12
Pages: 23
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Publication
2320577 | J:10399
First Author: Woychik RP
Year: 1990
Journal: Proc Natl Acad Sci U S A
Title: Molecular and genetic characterization of a radiation-induced structural rearrangement in mouse chromosome 2 causing mutations at the limb deformity and agouti loci.
Volume: 87
Issue: 7
Pages: 2588-92
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Publication
19383632 | J:149484
First Author: Zhou F
Year: 2009
Journal: Hum Mol Genet
Title: Formin1 disruption confers oligodactylism and alters Bmp signaling.
Volume: 18
Issue: 13
Pages: 2472-82
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21552539 | J:172359
First Author: Gonçalves A
Year: 2011
Journal: PLoS One
Title: Genetic analysis reveals an unexpected role of BMP7 in initiation of ureteric bud outgrowth in mouse embryos.
Volume: 6
Issue: 4
Pages: e19370
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Publication
35931033 | J:347568
First Author: Goto N
Year: 2022
Journal: Cell Stem Cell
Title: Lymphatics and fibroblasts support intestinal stem cells in homeostasis and injury.
Volume: 29
Issue: 8
Pages: 1246-1261.e6
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15198975 | J:91385
First Author: Zuniga A
Year: 2004
Journal: Genes Dev
Title: Mouse limb deformity mutations disrupt a global control region within the large regulatory landscape required for Gremlin expression.
Volume: 18
Issue: 13
Pages: 1553-64
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Publication
- | J:13381
 
First Author: Russell LB
Year: 1960
Journal: Mouse News Lett
Title: Limb-deformity, ld
Volume: 22
Pages: 50
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33903764 | J:305302
First Author: Kapoor VN
Year: 2021
Journal: Nat Immunol
Title: Gremlin 1+ fibroblastic niche maintains dendritic cell homeostasis in lymphoid tissues.
Volume: 22
Issue: 5
Pages: 571-585
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22247494 | J:196631
First Author: Cahill E
Year: 2012
Journal: Circulation
Title: Gremlin plays a key role in the pathogenesis of pulmonary hypertension.
Volume: 125
Issue: 7
Pages: 920-30
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17077323 | J:145361
First Author: Stabile H
Year: 2007
Journal: Blood
Title: Bone morphogenic protein antagonist Drm/gremlin is a novel proangiogenic factor.
Volume: 109
Issue: 5
Pages: 1834-40
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15539560 | J:95780
First Author: Gazzerro E
Year: 2005
Journal: Endocrinology
Title: Skeletal overexpression of gremlin impairs bone formation and causes osteopenia.
Volume: 146
Issue: 2
Pages: 655-65
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24160323 | J:202740
First Author: Ciuclan L
Year: 2013
Journal: Am J Pathol
Title: Treatment with anti-gremlin 1 antibody ameliorates chronic hypoxia/SU5416-induced pulmonary arterial hypertension in mice.
Volume: 183
Issue: 5
Pages: 1461-73
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Publication
- | J:13658
 
First Author: Kleinebrecht
Year: 1974
Journal: Mouse News Lett
Title: ld
Volume: 51
Pages: 19
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2612902 | J:46539
First Author: Zeller R
Year: 1989
Journal: Genes Dev
Title: The limb deformity gene is required for apical ectodermal ridge differentiation and anteroposterior limb pattern formation.
Volume: 3
Issue: 10
Pages: 1481-92
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Publication
- | J:22158
 
First Author: Cupp MB
Year: 1958
Journal: Mouse News Lett
Title: Severe appendicular abnormality
Volume: 19
Pages: 37
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- | J:22160
 
First Author: Cupp MB
Year: 1962
Journal: Mouse News Lett
Title: Note on identity of mutants
Volume: 26
Pages: 51
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- | J:171
 
First Author: Green MC
Year: 1962
Journal: Mouse News Lett
Title: Limb deformity, ld.
Volume: 26
Pages: 34-5
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Publication
- | J:82800
     
First Author: Ward-Bailey PF
Year: 2003
Journal: MGI Direct Data Submission
Title: A remutation to Fmnld-J named Forminlimb deformity-3J. Mouse Mutant Resources Web Site, The Jackson Laboratory, Bar Harbor, Maine
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9660951 | J:47309
First Author: Hsu DR
Year: 1998
Journal: Mol Cell
Title: The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities.
Volume: 1
Issue: 5
Pages: 673-83
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30926814 | J:274013
First Author: Chang SH
Year: 2019
Journal: Nat Commun
Title: Excessive mechanical loading promotes osteoarthritis through the gremlin-1-NF-κB pathway.
Volume: 10
Issue: 1
Pages: 1442
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32084389 | J:353212
First Author: McCarthy N
Year: 2020
Journal: Cell Stem Cell
Title: Distinct Mesenchymal Cell Populations Generate the Essential Intestinal BMP Signaling Gradient.
Volume: 26
Issue: 3
Pages: 391-402.e5
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38042929 | J:359680
First Author: Manieri E
Year: 2023
Journal: Nat Commun
Title: Role of PDGFRA(+) cells and a CD55(+) PDGFRA(Lo) fraction in the gastric mesenchymal niche.
Volume: 14
Issue: 1
Pages: 7978
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Publication
- | J:237690
     
First Author: Da Costa CR
Year: 2016
Journal: Personal Communication
Title: Deletion of FRT-flanked neo cassette from Grem1tm1Ecan
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12135612 | J:183226
First Author: Chen B
Year: 2002
Journal: Biochem Biophys Res Commun
Title: Drm/Gremlin transcriptionally activates p21(Cip1) via a novel mechanism and inhibits neoplastic transformation.
Volume: 295
Issue: 5
Pages: 1135-41
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20660291 | J:166472
First Author: Mitola S
Year: 2010
Journal: Blood
Title: Gremlin is a novel agonist of the major proangiogenic receptor VEGFR2.
Volume: 116
Issue: 18
Pages: 3677-80
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25810250 | J:225549
First Author: Lavoz C
Year: 2015
Journal: J Pathol
Title: Gremlin regulates renal inflammation via the vascular endothelial growth factor receptor 2 pathway.
Volume: 236
Issue: 4
Pages: 407-20
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9639362 | J:48401
First Author: Minabe-Saegusa C
Year: 1998
Journal: Dev Growth Differ
Title: Sequence and expression of a novel mouse gene PRDC (protein related to DAN and cerberus) identified by a gene trap approach.
Volume: 40
Issue: 3
Pages: 343-53
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15133038 | J:91788
First Author: Pangas SA
Year: 2004
Journal: J Biol Chem
Title: Growth differentiation factor 9 regulates expression of the bone morphogenetic protein antagonist gremlin.
Volume: 279
Issue: 31
Pages: 32281-6
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Publication
- | J:22159
 
First Author: Cupp MB
Year: 1960
Journal: Mouse News Lett
Title: Limb-deformity, ld
Volume: 22
Pages: 50
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11290528 | J:69302
First Author: Shi W
Year: 2001
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Gremlin negatively modulates BMP-4 induction of embryonic mouse lung branching morphogenesis.
Volume: 280
Issue: 5
Pages: L1030-9
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10965135 | J:64408
First Author: Zhang Q
Year: 2000
Journal: Cytogenet Cell Genet
Title: Cloning of the murine Drm gene (Cktsf1b1) and characterization of its oncogene suppressible promoter.
Volume: 89
Issue: 3-4
Pages: 242-51
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26284554 | J:230939
First Author: McDowell CM
Year: 2015
Journal: Invest Ophthalmol Vis Sci
Title: Gremlin Induces Ocular Hypertension in Mice Through Smad3-Dependent Signaling.
Volume: 56
Issue: 9
Pages: 5485-92
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29593116 | J:266800
 
First Author: Knickmeyer MD
Year: 2018
Journal: Open Biol
Title: TGFβ-facilitated optic fissure fusion and the role of bone morphogenetic protein antagonism.
Volume: 8
Issue: 3
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21978004 | J:178851
First Author: Passa O
Year: 2011
Journal: Immunology
Title: Compartmentalization of bone morphogenetic proteins and their antagonists in lymphoid progenitors and supporting microenvironments and functional implications.
Volume: 134
Issue: 3
Pages: 349-59
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16987511 | J:116987
First Author: Zuzarte-Luis V
Year: 2007
Journal: Dev Biol
Title: Lysosomal cathepsins in embryonic programmed cell death.
Volume: 301
Issue: 1
Pages: 205-17
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Publication
18505784 | J:138423
First Author: Mitola S
Year: 2008
Journal: Blood
Title: Angiopoietin-1 mediates the proangiogenic activity of the bone morphogenic protein antagonist Drm.
Volume: 112
Issue: 4
Pages: 1154-7
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Publication
10804186 | J:62028
First Author: Charité J
Year: 2000
Journal: Development
Title: The bHLH transcription factor dHAND controls Sonic hedgehog expression and establishment of the zone of polarizing activity during limb development.
Volume: 127
Issue: 11
Pages: 2461-70
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Publication
31076486 | J:278228
 
First Author: Reinhardt R
Year: 2019
Journal: Development
Title: Molecular signatures identify immature mesenchymal progenitors in early mouse limb buds that respond differentially to morphogen signaling.
Volume: 146
Issue: 10
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Publication
30375332 | J:269344
   
First Author: Teng CS
Year: 2018
Journal: Elife
Title: Altered bone growth dynamics prefigure craniosynostosis in a zebrafish model of Saethre-Chotzen syndrome.
Volume: 7
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23499659 | J:196597
First Author: Yamamoto-Shiraishi Y
Year: 2013
Journal: Dev Biol
Title: Wnt and BMP signaling cooperate with Hox in the control of Six2 expression in limb tendon precursor.
Volume: 377
Issue: 2
Pages: 363-74
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Publication
25774506 | J:222290
First Author: Jiang M
Year: 2015
Journal: J Clin Invest
Title: BMP-driven NRF2 activation in esophageal basal cell differentiation and eosinophilic esophagitis.
Volume: 125
Issue: 4
Pages: 1557-68
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Publication
18028901 | J:130204
First Author: Cook C
Year: 2007
Journal: Dev Biol
Title: Noggin is required for normal lobe patterning and ductal budding in the mouse prostate.
Volume: 312
Issue: 1
Pages: 217-30
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Publication
37028407 | J:334878
First Author: Kraiczy J
Year: 2023
Journal: Cell Stem Cell
Title: Graded BMP signaling within intestinal crypt architecture directs self-organization of the Wnt-secreting stem cell niche.
Volume: 30
Issue: 4
Pages: 433-449.e8
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Publication
28074039 | J:239521
First Author: Stzepourginski I
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: CD34+ mesenchymal cells are a major component of the intestinal stem cells niche at homeostasis and after injury.
Volume: 114
Issue: 4
Pages: E506-E513
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Publication
34750251 | J:317083
 
First Author: Letelier J
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: The Shh/Gli3 gene regulatory network precedes the origin of paired fins and reveals the deep homology between distal fins and digits.
Volume: 118
Issue: 46
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Publication
26837467 | J:236286
 
First Author: Wu X
Year: 2016
Journal: Nat Commun
Title: Autophagy regulates Notch degradation and modulates stem cell development and neurogenesis.
Volume: 7
Pages: 10533
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