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Search results 1 to 100 out of 212 for Hmgcr

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Category: Publication
Type Details Score
Publication
First Author: Hwang S
Year: 2016
Journal: J Biol Chem
Title: Contribution of Accelerated Degradation to Feedback Regulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase and Cholesterol Metabolism in the Liver.
Volume: 291
Issue: 26
Pages: 13479-94
Publication    
First Author: Jo Y
Year: 2019
Journal: Elife
Title: Schnyder corneal dystrophy-associated UBIAD1 inhibits ER-associated degradation of HMG CoA reductase in mice.
Volume: 8
Publication
First Author: Osaki Y
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Skeletal muscle-specific HMG-CoA reductase knockout mice exhibit rhabdomyolysis: A model for statin-induced myopathy.
Volume: 466
Issue: 3
Pages: 536-40
Publication  
First Author: Yeh YS
Year: 2018
Journal: iScience
Title: The Mevalonate Pathway Is Indispensable for Adipocyte Survival.
Volume: 9
Pages: 175-191
Publication
First Author: Nagashima S
Year: 2012
Journal: Arterioscler Thromb Vasc Biol
Title: Liver-specific deletion of 3-hydroxy-3-methylglutaryl coenzyme A reductase causes hepatic steatosis and death.
Volume: 32
Issue: 8
Pages: 1824-31
Publication
First Author: Doerfler AM
Year: 2022
Journal: Arterioscler Thromb Vasc Biol
Title: Intestinal Deletion of 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Promotes Expansion of the Resident Stem Cell Compartment.
Volume: 42
Issue: 4
Pages: 381-394
Publication
First Author: Ohashi K
Year: 2003
Journal: J Biol Chem
Title: Early embryonic lethality caused by targeted disruption of the 3-hydroxy-3-methylglutaryl-CoA reductase gene.
Volume: 278
Issue: 44
Pages: 42936-41
Publication
First Author: De Giorgi M
Year: 2020
Journal: J Lipid Res
Title: Depletion of essential isoprenoids and ER stress induction following acute liver-specific deletion of HMG-CoA reductase.
Volume: 61
Issue: 12
Pages: 1675-1686
Publication
First Author: Sonawane PJ
Year: 2011
Journal: PLoS One
Title: Functional promoter polymorphisms govern differential expression of HMG-CoA reductase gene in mouse models of essential hypertension.
Volume: 6
Issue: 1
Pages: e16661
Publication
First Author: Sundaresan S
Year: 1989
Journal: Somat Cell Mol Genet
Title: Genes for HMG-CoA reductase and serotonin 1a receptor are on mouse chromosome 13.
Volume: 15
Issue: 5
Pages: 465-9
Publication
First Author: Zhang X
Year: 2015
Journal: J Lipid Res
Title: Thyroid-stimulating hormone decreases HMG-CoA reductase phosphorylation via AMP-activated protein kinase in the liver.
Volume: 56
Issue: 5
Pages: 963-71
Publication
First Author: Takei A
Year: 2020
Journal: Diabetes
Title: Myeloid HMG-CoA Reductase Determines Adipose Tissue Inflammation, Insulin Resistance, and Hepatic Steatosis in Diet-Induced Obese Mice.
Volume: 69
Issue: 2
Pages: 158-164
Publication  
First Author: Zhong S
Year: 2021
Journal: Redox Biol
Title: Acetaldehyde Dehydrogenase 2 regulates HMG-CoA reductase stability and cholesterol synthesis in the liver.
Volume: 41
Pages: 101919
Publication
First Author: Lu XY
Year: 2020
Journal: Nature
Title: Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis.
Volume: 588
Issue: 7838
Pages: 479-484
Publication
First Author: Lacher SM
Year: 2017
Journal: Cell Death Dis
Title: HMG-CoA reductase promotes protein prenylation and therefore is indispensible for T-cell survival.
Volume: 8
Issue: 5
Pages: e2824
Publication
First Author: Hwang S
Year: 2017
Journal: J Biol Chem
Title: Hypoxia-inducible factor 1α activates insulin-induced gene 2 (Insig-2) transcription for degradation of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase in the liver.
Volume: 292
Issue: 22
Pages: 9382-9393
Publication
First Author: Sakai K
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Myeloid HMG-CoA (3-Hydroxy-3-Methylglutaryl-Coenzyme A) Reductase Determines Atherosclerosis by Modulating Migration of Macrophages.
Volume: 38
Issue: 11
Pages: 2590-2600
Publication
First Author: Helmberg A
Year: 1990
Journal: J Immunol
Title: Glucocorticoid-regulated gene expression in the immune system. Analysis of glucocorticoid-regulated transcripts from the mouse macrophage-like cell line P388D1.
Volume: 145
Issue: 12
Pages: 4332-7
Publication
First Author: Tsai YC
Year: 2012
Journal: Mol Biol Cell
Title: Differential regulation of HMG-CoA reductase and Insig-1 by enzymes of the ubiquitin-proteasome system.
Volume: 23
Issue: 23
Pages: 4484-94
Publication
First Author: Marijanovic Z
Year: 2003
Journal: Mol Endocrinol
Title: Closing the gap: identification of human 3-ketosteroid reductase, the last unknown enzyme of mammalian cholesterol biosynthesis.
Volume: 17
Issue: 9
Pages: 1715-25
Publication  
First Author: Ding J
Year: 2008
Journal: BMC Dev Biol
Title: Inhibition of HMG CoA reductase reveals an unexpected role for cholesterol during PGC migration in the mouse.
Volume: 8
Pages: 120
Publication
First Author: Edwards W
Year: 2023
Journal: Dev Cell
Title: Quantitative proteomic profiling identifies global protein network dynamics in murine embryonic heart development.
Volume: 58
Issue: 12
Pages: 1087-1105.e4
Publication
First Author: Li W
Year: 2005
Journal: Curr Biol
Title: The HMG-CoA reductase inhibitor lovastatin reverses the learning and attention deficits in a mouse model of neurofibromatosis type 1.
Volume: 15
Issue: 21
Pages: 1961-7
Publication
First Author: Cho SY
Year: 2011
Journal: FEBS Lett
Title: Linalool reduces the expression of 3-hydroxy-3-methylglutaryl CoA reductase via sterol regulatory element binding protein-2- and ubiquitin-dependent mechanisms.
Volume: 585
Issue: 20
Pages: 3289-96
Publication
First Author: Ying Z
Year: 2012
Journal: J Lipid Res
Title: Modified methylenedioxyphenol analogs lower LDL cholesterol through induction of LDL receptor expression.
Volume: 53
Issue: 5
Pages: 879-87
Publication
First Author: Bell JR
Year: 1993
Journal: Genomics
Title: Genomic structure, chromosomal location, and evolution of the mouse Hox 8 gene.
Volume: 16
Issue: 1
Pages: 123-31
Publication
First Author: Raben N
Year: 2002
Journal: Mol Ther
Title: Glycogen stored in skeletal but not in cardiac muscle in acid alpha-glucosidase mutant (Pompe) mice is highly resistant to transgene-encoded human enzyme.
Volume: 6
Issue: 5
Pages: 601-8
Publication
First Author: Hanaka S
Year: 2000
Journal: Brain Dev
Title: Gene expression related to cholesterol metabolism in mouse brain during development.
Volume: 22
Issue: 5
Pages: 321-6
Publication
First Author: Engelking LJ
Year: 2005
Journal: J Clin Invest
Title: Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins.
Volume: 115
Issue: 9
Pages: 2489-98
Publication
First Author: Wu MK
Year: 2005
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Altered hepatic cholesterol metabolism compensates for disruption of phosphatidylcholine transfer protein in mice.
Volume: 289
Issue: 3
Pages: G456-61
Publication
First Author: Karmaus PWF
Year: 2019
Journal: Nature
Title: Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity.
Volume: 565
Issue: 7737
Pages: 101-105
Publication
First Author: Patel DD
Year: 2001
Journal: J Lipid Res
Title: Disturbances in the normal regulation of SREBP-sensitive genes in PPAR alpha-deficient mice.
Volume: 42
Issue: 3
Pages: 328-37
Publication
First Author: Buchovecky CM
Year: 2013
Journal: Nat Genet
Title: A suppressor screen in Mecp2 mutant mice implicates cholesterol metabolism in Rett syndrome.
Volume: 45
Issue: 9
Pages: 1013-20
Publication
First Author: Plump AS
Year: 1996
Journal: J Clin Invest
Title: Apolipoprotein A-I is required for cholesteryl ester accumulation in steroidogenic cells and for normal adrenal steroid production.
Volume: 97
Issue: 11
Pages: 2660-71
Publication
First Author: Ghimire S
Year: 2021
Journal: PLoS One
Title: PEG3 controls lipogenesis through ACLY.
Volume: 16
Issue: 5
Pages: e0252354
Publication
First Author: Hyogo H
Year: 2002
Journal: J Biol Chem
Title: Leptin promotes biliary cholesterol elimination during weight loss in ob/ob mice by regulating the enterohepatic circulation of bile salts.
Volume: 277
Issue: 37
Pages: 34117-24
Publication
First Author: Tamboli IY
Year: 2010
Journal: J Biol Chem
Title: Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion.
Volume: 285
Issue: 48
Pages: 37405-14
Publication
First Author: Rub A
Year: 2009
Journal: Nat Immunol
Title: Cholesterol depletion associated with Leishmania major infection alters macrophage CD40 signalosome composition and effector function.
Volume: 10
Issue: 3
Pages: 273-80
Publication  
First Author: Okamoto-Uchida Y
Year: 2016
Journal: Sci Rep
Title: The mevalonate pathway regulates primitive streak formation via protein farnesylation.
Volume: 6
Pages: 37697
Publication
First Author: Goodrum JF
Year: 1995
Journal: J Neurochem
Title: Nerve regeneration and cholesterol reutilization occur in the absence of apolipoproteins E and A-I in mice.
Volume: 64
Issue: 1
Pages: 408-16
Publication
First Author: Timilshina M
Year: 2019
Journal: Cell Rep
Title: Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells.
Volume: 27
Issue: 10
Pages: 2948-2961.e7
Publication
First Author: Plump AS
Year: 1997
Journal: J Lipid Res
Title: ApoA-I knockout mice: characterization of HDL metabolism in homozygotes and identification of a post-RNA mechanism of apoA-I up-regulation in heterozygotes.
Volume: 38
Issue: 5
Pages: 1033-47
Publication
First Author: Welch CL
Year: 2004
Journal: Physiol Genomics
Title: Novel QTLs for HDL levels identified in mice by controlling for Apoa2 allelic effects: confirmation of a chromosome 6 locus in a congenic strain.
Volume: 17
Issue: 1
Pages: 48-59
Publication
First Author: Hwa JJ
Year: 1992
Journal: J Lipid Res
Title: Genetic and dietary interactions in the regulation of HMG-CoA reductase gene expression.
Volume: 33
Issue: 5
Pages: 711-25
Publication
First Author: Hasegawa S
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Acetoacetyl-CoA synthetase is essential for normal neuronal development.
Volume: 427
Issue: 2
Pages: 398-403
Publication
First Author: Su W
Year: 2020
Journal: Cell Metab
Title: Protein Prenylation Drives Discrete Signaling Programs for the Differentiation and Maintenance of Effector Treg Cells.
Volume: 32
Issue: 6
Pages: 996-1011.e7
Publication
First Author: Hogenboom S
Year: 2002
Journal: J Lipid Res
Title: Absence of functional peroxisomes does not lead to deficiency of enzymes involved in cholesterol biosynthesis.
Volume: 43
Issue: 1
Pages: 90-8
Publication
First Author: Myöhänen S
Year: 1994
Journal: DNA Seq
Title: Nucleotide sequence of mouse spermidine synthase cDNA.
Volume: 4
Issue: 5
Pages: 343-6
Publication
First Author: Yubero P
Year: 2004
Journal: Endocrinology
Title: The developmental regulation of peroxisome proliferator-activated receptor-gamma coactivator-1alpha expression in the liver is partially dissociated from the control of gluconeogenesis and lipid catabolism.
Volume: 145
Issue: 9
Pages: 4268-77
Publication
First Author: Cunningham D
Year: 2015
Journal: Hum Mol Genet
Title: Analysis of hedgehog signaling in cerebellar granule cell precursors in a conditional Nsdhl allele demonstrates an essential role for cholesterol in postnatal CNS development.
Volume: 24
Issue: 10
Pages: 2808-25
Publication
First Author: Kim M
Year: 2018
Journal: Genes Dev
Title: Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells.
Volume: 32
Issue: 9-10
Pages: 645-657
Publication
First Author: Munkacsi AB
Year: 2017
Journal: J Biol Chem
Title: Normalization of Hepatic Homeostasis in the Npc1nmf164 Mouse Model of Niemann-Pick Type C Disease Treated with the Histone Deacetylase Inhibitor Vorinostat.
Volume: 292
Issue: 11
Pages: 4395-4410
Publication  
First Author: Van Veldhoven PP
Year: 2020
Journal: Front Cell Dev Biol
Title: Slc25a17 Gene Trapped Mice: PMP34 Plays a Role in the Peroxisomal Degradation of Phytanic and Pristanic Acid.
Volume: 8
Pages: 144
Publication
First Author: Li J
Year: 1999
Journal: Nat Genet
Title: Leukaemia disease genes: large-scale cloning and pathway predictions.
Volume: 23
Issue: 3
Pages: 348-53
Publication
First Author: Shimano H
Year: 1996
Journal: J Clin Invest
Title: Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a.
Volume: 98
Issue: 7
Pages: 1575-84
Publication  
First Author: Tsushima H
Year: 2018
Journal: Development
Title: Intracellular biosynthesis of lipids and cholesterol by Scap and Insig in mesenchymal cells regulates long bone growth and chondrocyte homeostasis.
Volume: 145
Issue: 13
Publication
First Author: Patra D
Year: 2014
Journal: PLoS One
Title: Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis.
Volume: 9
Issue: 8
Pages: e105674
Publication
First Author: Vergnes L
Year: 2016
Journal: J Lipid Res
Title: SREBP-2-deficient and hypomorphic mice reveal roles for SREBP-2 in embryonic development and SREBP-1c expression.
Volume: 57
Issue: 3
Pages: 410-21
Publication
First Author: Wei L
Year: 2020
Journal: J Biol Chem
Title: GGPP depletion initiates metaflammation through disequilibrating CYB5R3-dependent eicosanoid metabolism.
Volume: 295
Issue: 47
Pages: 15988-16001
Publication  
First Author: Guo CG
Year: 2023
Journal: Mol Metab
Title: Intestinal SURF4 is essential for apolipoprotein transport and lipoprotein secretion.
Volume: 79
Pages: 101847
Publication
First Author: Shin SW
Year: 2017
Journal: Nat Commun
Title: Cytoplasmic cleavage of DPPA3 is required for intracellular trafficking and cleavage-stage development in mice.
Volume: 8
Issue: 1
Pages: 1643
Publication
First Author: Beigneux AP
Year: 2004
Journal: J Biol Chem
Title: ATP-citrate lyase deficiency in the mouse.
Volume: 279
Issue: 10
Pages: 9557-64
Publication  
First Author: Kobayashi K
Year: 2023
Journal: Life Sci Alliance
Title: Feto-maternal cholesterol transport regulated by β-Klotho-FGF15 axis is essential for fetal growth.
Volume: 6
Issue: 10
Publication
First Author: Hong AE
Year: 2018
Journal: Mol Cells
Title: PPARα-Target Gene Expression Requires TIS21/BTG2 Gene in Liver of the C57BL/6 Mice under Fasting Condition.
Volume: 41
Issue: 2
Pages: 140-149
Publication
First Author: Seymour AB
Year: 1996
Journal: Genome Res
Title: An integrated genetic map of the pearl locus of mouse chromosome 13.
Volume: 6
Issue: 6
Pages: 538-44
Publication
First Author: Bojanic DD
Year: 2010
Journal: J Lipid Res
Title: Differential expression and function of ABCG1 and ABCG4 during development and aging.
Volume: 51
Issue: 1
Pages: 169-81
Publication
First Author: Fonseca TL
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity.
Volume: 112
Issue: 45
Pages: 14018-23
Publication
First Author: Desmazières A
Year: 2008
Journal: J Neurosci
Title: Disruption of Krox20-Nab interaction in the mouse leads to peripheral neuropathy with biphasic evolution.
Volume: 28
Issue: 23
Pages: 5891-900
Publication  
First Author: Jiang M
Year: 2016
Journal: Nat Commun
Title: Regulation of PERK-eIF2α signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes.
Volume: 7
Pages: 12185
Publication  
First Author: Scortegagna M
Year: 2017
Journal: JCI Insight
Title: The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion.
Volume: 2
Issue: 23
Publication
First Author: Taylor BA
Year: 1993
Journal: Genomics
Title: The MEV mouse linkage testing stock: mapping 30 novel proviral insertions and establishment of an improved stock.
Volume: 16
Issue: 2
Pages: 380-94
Publication
First Author: ÅžiÅŸecioÄŸlu M
Year: 2015
Journal: J Lipid Res
Title: A compendium of expression patterns of cholesterol biosynthetic enzymes in the mouse embryo.
Volume: 56
Issue: 8
Pages: 1551-9
Publication
First Author: Sacchetti P
Year: 2009
Journal: Cell Stem Cell
Title: Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells.
Volume: 5
Issue: 4
Pages: 409-19
Publication
First Author: Briançon N
Year: 2006
Journal: EMBO J
Title: In vivo role of the HNF4alpha AF-1 activation domain revealed by exon swapping.
Volume: 25
Issue: 6
Pages: 1253-62
Publication
First Author: Lammert F
Year: 2001
Journal: Gastroenterology
Title: Chromosomal organization of candidate genes involved in cholesterol gallstone formation: a murine gallstone map.
Volume: 120
Issue: 1
Pages: 221-38
Publication
First Author: Warden CH
Year: 1993
Journal: Genomics
Title: Linkage mapping of 40 randomly isolated liver cDNA clones in the mouse.
Volume: 18
Issue: 2
Pages: 295-307
Publication
First Author: Welch CL
Year: 1996
Journal: J Lipid Res
Title: Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes.
Volume: 37
Issue: 7
Pages: 1406-21
Publication  
First Author: Ahuja N
Year: 2022
Journal: Dev Biol
Title: Endothelial Cyp26b1 restrains murine heart valve growth during development.
Volume: 486
Pages: 81-95
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication      
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load