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Search results 1 to 100 out of 127 for Lgr4

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Category: Publication
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Type Details Score
Publication
30406697 | J:278480
First Author: Li Z
Year: 2019
Journal: Am J Physiol Gastrointest Liver Physiol
Title: LGR4 protects hepatocytes from injury in mouse.
Volume: 316
Issue: 1
Pages: G123-G131
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Publication
26333992 | J:227517
First Author: Koizumi M
Year: 2015
Journal: Biol Reprod
Title: Lgr4 controls specialization of female gonads in mice.
Volume: 93
Issue: 4
Pages: 90
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Publication
29269400 | J:273817
First Author: Yue Z
Year: 2018
Journal: FASEB J
Title: LGR4 modulates breast cancer initiation, metastasis, and cancer stem cells.
Volume: 32
Issue: 5
Pages: 2422-2437
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Publication
32493844 | J:308970
 
First Author: Mancini A
Year: 2020
Journal: JCI Insight
Title: LGR4 deficiency results in delayed puberty through impaired Wnt/β-catenin signaling.
Volume: 5
Issue: 11
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Publication
20638054 | J:307452
First Author: Mohri Y
Year: 2010
Journal: Fertil Steril
Title: Reduced fertility with impairment of early-stage embryos observed in mice lacking Lgr4 in epithelial tissues.
Volume: 94
Issue: 7
Pages: 2878-81
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Publication
17850793 | J:126813
First Author: Kato S
Year: 2007
Journal: FEBS Lett
Title: Eye-open at birth phenotype with reduced keratinocyte motility in LGR4 null mice.
Volume: 581
Issue: 24
Pages: 4685-90
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Publication
16406039 | J:105945
First Author: Mendive F
Year: 2006
Journal: Dev Biol
Title: Defective postnatal development of the male reproductive tract in LGR4 knockout mice.
Volume: 290
Issue: 2
Pages: 421-34
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Publication
19301269 | J:174171
First Author: Lambot MA
Year: 2009
Journal: Anat Rec (Hoboken)
Title: Three-dimensional reconstruction of efferent ducts in wild-type and Lgr4 knock-out mice.
Volume: 292
Issue: 4
Pages: 595-603
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Publication
24212090 | J:208298
First Author: Wang J
Year: 2013
Journal: Nat Cell Biol
Title: Ablation of LGR4 promotes energy expenditure by driving white-to-brown fat switch.
Volume: 15
Issue: 12
Pages: 1455-63
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Publication
17079737 | J:121125
First Author: Hoshii T
Year: 2007
Journal: Biol Reprod
Title: LGR4 regulates the postnatal development and integrity of male reproductive tracts in mice.
Volume: 76
Issue: 2
Pages: 303-13
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Publication
23897697 | J:204016
First Author: Luo W
Year: 2013
Journal: Stem Cells
Title: Lgr4 is a key regulator of prostate development and prostate stem cell differentiation.
Volume: 31
Issue: 11
Pages: 2492-505
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Publication
24877628 | J:217023
First Author: Pan H
Year: 2014
Journal: Endocrinology
Title: Lgr4 gene regulates corpus luteum maturation through modulation of the WNT-mediated EGFR-ERK signaling pathway.
Volume: 155
Issue: 9
Pages: 3624-37
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Publication
32035093 | J:293867
First Author: Ren X
Year: 2020
Journal: J Invest Dermatol
Title: Lgr4 Deletion Delays the Hair Cycle and Inhibits the Activation of Hair Follicle Stem Cells.
Volume: 140
Issue: 9
Pages: 1706-1712.e4
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Publication
26102032 | J:228673
First Author: Sun Y
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Ablation of Lgr4 enhances energy adaptation in skeletal muscle via activation of Ampk/Sirt1/Pgc1α pathway.
Volume: 464
Issue: 2
Pages: 396-400
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Publication
30536377 | J:270886
     
First Author: Sun P
Year: 2018
Journal: J Cell Physiol
Title: Loss of Lgr4 inhibits differentiation, migration and apoptosis, and promotes proliferation in bone mesenchymal stem cells.
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Publication
23712846 | J:202723
First Author: Wang Y
Year: 2013
Journal: Stem Cells
Title: Lgr4 regulates mammary gland development and stem cell activity through the pluripotency transcription factor Sox2.
Volume: 31
Issue: 9
Pages: 1921-31
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Publication
21508962 | J:173765
First Author: Mustata RC
Year: 2011
Journal: EMBO Rep
Title: Lgr4 is required for Paneth cell differentiation and maintenance of intestinal stem cells ex vivo.
Volume: 12
Issue: 6
Pages: 558-64
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Publication
21693646 | J:198905
First Author: Carmon KS
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling.
Volume: 108
Issue: 28
Pages: 11452-7
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Publication
24353284 | J:216037
First Author: Wang F
Year: 2014
Journal: J Mol Endocrinol
Title: LGR4 acts as a link between the peripheral circadian clock and lipid metabolism in liver.
Volume: 52
Issue: 2
Pages: 133-43
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Publication
27064449 | J:235185
First Author: Luo J
Year: 2016
Journal: Nat Med
Title: LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption.
Volume: 22
Issue: 5
Pages: 539-46
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Publication
22738954 | J:186318
First Author: Mohri Y
Year: 2012
Journal: Biosci Biotechnol Biochem
Title: LGR4 is required for the cell survival of the peripheral mesenchyme at the embryonic stages of nephrogenesis.
Volume: 76
Issue: 5
Pages: 888-91
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Publication
25063812 | J:250415
First Author: Guan X
Year: 2014
Journal: J Biol Chem
Title: Lgr4 protein deficiency induces ataxia-like phenotype in mice and impairs long term depression at cerebellar parallel fiber-Purkinje cell synapses.
Volume: 289
Issue: 38
Pages: 26492-504
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Publication
23975934 | J:203941
First Author: Sone M
Year: 2013
Journal: FASEB J
Title: LGR4 expressed in uterine epithelium is necessary for uterine gland development and contributes to decidualization in mice.
Volume: 27
Issue: 12
Pages: 4917-28
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Publication
23393138 | J:197850
First Author: Liu S
Year: 2013
Journal: J Biol Chem
Title: Lgr4 gene deficiency increases susceptibility and severity of dextran sodium sulfate-induced inflammatory bowel disease in mice.
Volume: 288
Issue: 13
Pages: 8794-803; discussion 8804
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Publication
27693558 | J:237841
First Author: Xu P
Year: 2016
Journal: Cancer Lett
Title: Lgr4 is crucial for skin carcinogenesis by regulating MEK/ERK and Wnt/β-catenin signaling pathways.
Volume: 383
Issue: 2
Pages: 161-170
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Publication
27559308 | J:273440
 
First Author: Żak M
Year: 2016
Journal: Front Cell Neurosci
Title: LGR4 and LGR5 Regulate Hair Cell Differentiation in the Sensory Epithelium of the Developing Mouse Cochlea.
Volume: 10
Pages: 186
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Publication
24680895 | J:212415
First Author: Kinzel B
Year: 2014
Journal: Dev Biol
Title: Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice.
Volume: 390
Issue: 2
Pages: 181-90
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Publication
28634819 | J:252705
First Author: Kriz V
Year: 2017
Journal: Transgenic Res
Title: Establishment of a tagged variant of Lgr4 receptor suitable for functional and expression studies in the mouse.
Volume: 26
Issue: 5
Pages: 689-701
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Publication
25811370 | J:229263
First Author: Zhu J
Year: 2015
Journal: PLoS One
Title: Targeted deletion of the murine Lgr4 gene decreases lens epithelial cell resistance to oxidative stress and induces age-related cataract formation.
Volume: 10
Issue: 3
Pages: e0119599
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Publication
16028069 | J:158050
First Author: Van Schoore G
Year: 2005
Journal: Histochem Cell Biol
Title: Expression pattern of the orphan receptor LGR4/GPR48 gene in the mouse.
Volume: 124
Issue: 1
Pages: 35-50
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16785743 | J:127019
First Author: Kato S
Year: 2006
Journal: Nephron Exp Nephrol
Title: Leucine-rich repeat-containing G protein-coupled receptor-4 (LGR4, Gpr48) is essential for renal development in mice.
Volume: 104
Issue: 2
Pages: e63-75
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Publication
28768769 | J:246044
First Author: Luo W
Year: 2017
Journal: J Biol Chem
Title: Leucine-rich repeat-containing G protein-coupled receptor 4 (Lgr4) is necessary for prostate cancer metastasis via epithelial-mesenchymal transition.
Volume: 292
Issue: 37
Pages: 15525-15537
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Publication
24519938 | J:212439
First Author: Yi T
Year: 2014
Journal: J Biol Chem
Title: LGR4/GPR48 inactivation leads to aniridia-genitourinary anomalies-mental retardation syndrome defects.
Volume: 289
Issue: 13
Pages: 8767-80
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Publication
31376385 | J:284290
First Author: Wu J
Year: 2020
Journal: J Invest Dermatol
Title: MicroRNA-34 Family Enhances Wound Inflammation by Targeting LGR4.
Volume: 140
Issue: 2
Pages: 465-476.e11
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28842478 | J:246020
First Author: Zhang N
Year: 2017
Journal: J Biol Chem
Title: Leucine-rich repeat-containing G protein-coupled receptor 4 facilitates vesicular stomatitis virus infection by binding vesicular stomatitis virus glycoprotein.
Volume: 292
Issue: 40
Pages: 16527-16538
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Publication
23533175 | J:195273
First Author: Qian Y
Year: 2013
Journal: Development
Title: Lgr4-mediated Wnt/β-catenin signaling in peritubular myoid cells is essential for spermatogenesis.
Volume: 140
Issue: 8
Pages: 1751-61
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18651655 | J:139012
First Author: Mohri Y
Year: 2008
Journal: Dev Dyn
Title: Impaired hair placode formation with reduced expression of hair follicle-related genes in mice lacking Lgr4.
Volume: 237
Issue: 8
Pages: 2235-42
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19301403 | J:147036
First Author: Yamashita R
Year: 2009
Journal: Dev Dyn
Title: Defective development of the gall bladder and cystic duct in Lgr4- hypomorphic mice.
Volume: 238
Issue: 4
Pages: 993-1000
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Publication
29967265 | J:265563
First Author: Tan B
Year: 2018
Journal: Cancer Res
Title: Inhibition of Rspo-Lgr4 Facilitates Checkpoint Blockade Therapy by Switching Macrophage Polarization.
Volume: 78
Issue: 17
Pages: 4929-4942
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Publication
32926477 | J:306915
First Author: Liu S
Year: 2020
Journal: FASEB J
Title: Rspo1/Rspo3-LGR4 signaling inhibits hepatic cholesterol synthesis through the AMPKα-SREBP2 pathway.
Volume: 34
Issue: 11
Pages: 14946-14959
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Publication
21523854 | J:172277
First Author: Mohri Y
Year: 2011
Journal: Dev Dyn
Title: Lgr4-deficient mice showed premature differentiation of ureteric bud with reduced expression of Wnt effector Lef1 and Gata3.
Volume: 240
Issue: 6
Pages: 1626-34
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Publication
29859889 | J:264603
First Author: Da Silva F
Year: 2018
Journal: Dev Biol
Title: Myocardial-specific R-spondin3 drives proliferation of the coronary stems primarily through the Leucine Rich Repeat G Protein coupled receptor LGR4.
Volume: 441
Issue: 1
Pages: 42-51
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21727895 | J:174842
First Author: de Lau W
Year: 2011
Journal: Nature
Title: Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling.
Volume: 476
Issue: 7360
Pages: 293-7
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Publication
24344199 | J:316107
First Author: Han XH
Year: 2014
Journal: Mol Cell Biol
Title: Regulation of the follistatin gene by RSPO-LGR4 signaling via activation of the WNT/β-catenin pathway in skeletal myogenesis.
Volume: 34
Issue: 4
Pages: 752-64
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Publication
37651925 | J:341172
 
First Author: Watanabe K
Year: 2023
Journal: Gene Expr Patterns
Title: Spatiotemporal expression patterns of R-spondins and their receptors, Lgrs, in the developing mouse telencephalon.
Volume: 49
Pages: 119333
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Publication
15192078 | J:92077
First Author: Mazerbourg S
Year: 2004
Journal: Mol Endocrinol
Title: Leucine-rich repeat-containing, G protein-coupled receptor 4 null mice exhibit intrauterine growth retardation associated with embryonic and perinatal lethality.
Volume: 18
Issue: 9
Pages: 2241-54
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24595031 | J:214699
First Author: Dang Y
Year: 2014
Journal: PLoS One
Title: Gpr48 deficiency induces polycystic kidney lesions and renal fibrosis in mice by activating Wnt signal pathway.
Volume: 9
Issue: 3
Pages: e89835
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20023170 | J:157158
First Author: Li XY
Year: 2010
Journal: Development
Title: G protein-coupled receptor 48 upregulates estrogen receptor alpha expression via cAMP/PKA signaling in the male reproductive tract.
Volume: 137
Issue: 1
Pages: 151-7
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11401528 | J:68632
First Author: Loh ED
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Molecular characterization of a novel glycoprotein hormone G-protein-coupled receptor.
Volume: 282
Issue: 3
Pages: 757-64
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22135314 | J:286885
First Author: Wang J
Year: 2012
Journal: J Am Soc Nephrol
Title: GPR48 increases mineralocorticoid receptor gene expression.
Volume: 23
Issue: 2
Pages: 281-93
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18487371 | J:141686
First Author: Jin C
Year: 2008
Journal: Invest Ophthalmol Vis Sci
Title: GPR48 regulates epithelial cell proliferation and migration by activating EGFR during eyelid development.
Volume: 49
Issue: 10
Pages: 4245-53
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36410420 | J:344581
First Author: Saponara E
Year: 2023
Journal: Am J Pathol
Title: Loss of Hepatic Leucine-Rich Repeat-Containing G-Protein Coupled Receptors 4 and 5 Promotes Nonalcoholic Fatty Liver Disease.
Volume: 193
Issue: 2
Pages: 161-181
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Publication
23589304 | J:198965
First Author: Du B
Year: 2013
Journal: J Biol Chem
Title: Lgr4/Gpr48 negatively regulates TLR2/4-associated pattern recognition and innate immunity by targeting CD14 expression.
Volume: 288
Issue: 21
Pages: 15131-41
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Publication
20732323 | J:164387
First Author: Wang Z
Year: 2010
Journal: FEBS Lett
Title: GPR48-Induced keratinocyte proliferation occurs through HB-EGF mediated EGFR transactivation.
Volume: 584
Issue: 18
Pages: 4057-62
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Publication
24139799 | J:203768
First Author: Mustata RC
Year: 2013
Journal: Cell Rep
Title: Identification of Lgr5-independent spheroid-generating progenitors of the mouse fetal intestinal epithelium.
Volume: 5
Issue: 2
Pages: 421-32
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Publication
32839607 | J:306004
First Author: Zhou B
Year: 2020
Journal: Nat Immunol
Title: The angiocrine Rspondin3 instructs interstitial macrophage transition via metabolic-epigenetic reprogramming and resolves inflammatory injury.
Volume: 21
Issue: 11
Pages: 1430-1443
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Publication
32457899 | J:290019
 
First Author: Jin YR
Year: 2020
Journal: Front Cell Dev Biol
Title: Canonical WNT/β-Catenin Signaling Activated by WNT9b and RSPO2 Cooperation Regulates Facial Morphogenesis in Mice.
Volume: 8
Pages: 264
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24616052 | J:210988
First Author: Kawasaki M
Year: 2014
Journal: Dev Dyn
Title: R-spondins/Lgrs expression in tooth development.
Volume: 243
Issue: 6
Pages: 844-51
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25910078 | J:239281
First Author: Caruso M
Year: 2015
Journal: PLoS One
Title: R-spondin 1/dickkopf-1/beta-catenin machinery is involved in testicular embryonic angiogenesis.
Volume: 10
Issue: 4
Pages: e0124213
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20223988 | J:157895
First Author: Snippert HJ
Year: 2010
Journal: Science
Title: Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin.
Volume: 327
Issue: 5971
Pages: 1385-9
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29769720 | J:262420
First Author: Szenker-Ravi E
Year: 2018
Journal: Nature
Title: RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6.
Volume: 557
Issue: 7706
Pages: 564-569
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18955481 | J:144074
First Author: Song H
Year: 2008
Journal: J Biol Chem
Title: Inactivation of G-protein-coupled receptor 48 (Gpr48/Lgr4) impairs definitive erythropoiesis at midgestation through down-regulation of the ATF4 signaling pathway.
Volume: 283
Issue: 52
Pages: 36687-97
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16822657 | J:111998
First Author: Reinholdt LG
Year: 2006
Journal: Mech Dev
Title: The mouse gcd2 mutation causes primordial germ cell depletion.
Volume: 123
Issue: 7
Pages: 559-69
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30146491 | J:308689
First Author: Gyllborg D
Year: 2018
Journal: Stem Cell Reports
Title: The Matricellular Protein R-Spondin 2 Promotes Midbrain Dopaminergic Neurogenesis and Differentiation.
Volume: 11
Issue: 3
Pages: 651-664
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28400434 | J:240534
First Author: Toivanen R
Year: 2017
Journal: Development
Title: Prostate organogenesis: tissue induction, hormonal regulation and cell type specification.
Volume: 144
Issue: 8
Pages: 1382-1398
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11242070 | J:67920
First Author: Leighton PA
Year: 2001
Journal: Nature
Title: Defining brain wiring patterns and mechanisms through gene trapping in mice.
Volume: 410
Issue: 6825
Pages: 174-9
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19605502 | J:152843
First Author: Luo J
Year: 2009
Journal: Development
Title: Regulation of bone formation and remodeling by G-protein-coupled receptor 48.
Volume: 136
Issue: 16
Pages: 2747-56
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26581094 | J:231699
First Author: Voutilainen M
Year: 2015
Journal: PLoS Genet
Title: Ectodysplasin/NF-κB Promotes Mammary Cell Fate via Wnt/β-catenin Pathway.
Volume: 11
Issue: 11
Pages: e1005676
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25158167 | J:216158
First Author: Rastetter RH
Year: 2014
Journal: Dev Biol
Title: Marker genes identify three somatic cell types in the fetal mouse ovary.
Volume: 394
Issue: 2
Pages: 242-52
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32468660 | J:312814
First Author: Fernandez Vallone V
Year: 2020
Journal: EMBO Rep
Title: LGR5 controls extracellular matrix production by stem cells in the developing intestine.
Volume: 21
Issue: 7
Pages: e49224
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19474196 | J:151902
First Author: Favor J
Year: 2009
Journal: Genetics
Title: Analysis of Pax6 contiguous gene deletions in the mouse, Mus musculus, identifies regions distinct from Pax6 responsible for extreme small-eye and belly-spotting phenotypes.
Volume: 182
Issue: 4
Pages: 1077-88
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27088858 | J:236636
First Author: Planas-Paz L
Year: 2016
Journal: Nat Cell Biol
Title: The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size.
Volume: 18
Issue: 5
Pages: 467-79
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26776520 | J:277950
First Author: Kang HM
Year: 2016
Journal: Cell Rep
Title: Sox9-Positive Progenitor Cells Play a Key Role in Renal Tubule Epithelial Regeneration in Mice.
Volume: 14
Issue: 4
Pages: 861-871
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32324134 | J:290543
   
First Author: Vidal VP
Year: 2020
Journal: Elife
Title: R-spondin signalling is essential for the maintenance and differentiation of mouse nephron progenitors.
Volume: 9
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Publication
18331719 | J:133339
First Author: Silvestri C
Year: 2008
Journal: Dev Cell
Title: Genome-wide identification of Smad/Foxh1 targets reveals a role for Foxh1 in retinoic acid regulation and forebrain development.
Volume: 14
Issue: 3
Pages: 411-23
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31772170 | J:283792
First Author: Seishima R
Year: 2019
Journal: Nat Commun
Title: Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development.
Volume: 10
Issue: 1
Pages: 5378
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18424556 | J:134299
First Author: Weng J
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Deletion of G protein-coupled receptor 48 leads to ocular anterior segment dysgenesis (ASD) through down-regulation of Pitx2.
Volume: 105
Issue: 16
Pages: 6081-6
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Publication
26273529 | J:227247
 
First Author: Brommage R
Year: 2014
Journal: Bone Res
Title: High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes.
Volume: 2
Pages: 14034
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Publication
28813421 | J:253067
First Author: Sigal M
Year: 2017
Journal: Nature
Title: Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis.
Volume: 548
Issue: 7668
Pages: 451-455
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Publication
- | J:29505
     
First Author: Copeland NG
Year: 1999
Journal: Database Release
Title: Copeland-Jenkins (Frederick) Interspecific Backcross Mapping Data
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29688375 | J:250512
   
First Author: Li J
Year: 2018
Journal: Database (Oxford)
Title: CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.
Volume: 2018
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10512203 | J:93290
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
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Publication
15840001 | J:110088
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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