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Search results 1 to 100 out of 162 for Mcu

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Category: Publication
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Type Details Score
Publication
21685886 | J:174848
First Author: Baughman JM
Year: 2011
Journal: Nature
Title: Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter.
Volume: 476
Issue: 7360
Pages: 341-5
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Publication
23900286 | J:201635
First Author: Raffaello A
Year: 2013
Journal: EMBO J
Title: The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunit.
Volume: 32
Issue: 17
Pages: 2362-76
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Publication
24792186 | J:250057
First Author: Murphy E
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Unresolved questions from the analysis of mice lacking MCU expression.
Volume: 449
Issue: 4
Pages: 384-5
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Publication
21685888 | J:174847
First Author: De Stefani D
Year: 2011
Journal: Nature
Title: A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter.
Volume: 476
Issue: 7360
Pages: 336-40
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Publication
27184846 | J:235756
First Author: Tomar D
Year: 2016
Journal: Cell Rep
Title: MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics.
Volume: 15
Issue: 8
Pages: 1673-85
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Publication
29686046 | J:265698
First Author: Niescier RF
Year: 2018
Journal: J Neurosci
Title: MCU Interacts with Miro1 to Modulate Mitochondrial Functions in Neurons.
Volume: 38
Issue: 20
Pages: 4666-4677
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Publication
27642048 | J:248860
First Author: König T
Year: 2016
Journal: Mol Cell
Title: The m-AAA Protease Associated with Neurodegeneration Limits MCU Activity in Mitochondria.
Volume: 64
Issue: 1
Pages: 148-162
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Publication
24231807 | J:203524
First Author: Sancak Y
Year: 2013
Journal: Science
Title: EMRE is an essential component of the mitochondrial calcium uniporter complex.
Volume: 342
Issue: 6164
Pages: 1379-82
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Publication
28262504 | J:251941
First Author: Dong Z
Year: 2017
Journal: Mol Cell
Title: Mitochondrial Ca2+ Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity.
Volume: 65
Issue: 6
Pages: 1014-1028.e7
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Publication
30858581 | J:282891
First Author: Zhao H
Year: 2019
Journal: Nat Cell Biol
Title: AMPK-mediated activation of MCU stimulates mitochondrial Ca2+ entry to promote mitotic progression.
Volume: 21
Issue: 4
Pages: 476-486
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Publication
31040260 | J:284458
 
First Author: Koval OM
Year: 2019
Journal: Sci Signal
Title: Loss of MCU prevents mitochondrial fusion in G1-S phase and blocks cell cycle progression and proliferation.
Volume: 12
Issue: 579
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Publication
26153425 | J:223794
First Author: Rasmussen TP
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Inhibition of MCU forces extramitochondrial adaptations governing physiological and pathological stress responses in heart.
Volume: 112
Issue: 29
Pages: 9129-34
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Publication
22829870 | J:189590
First Author: Tarasov AI
Year: 2012
Journal: PLoS One
Title: The mitochondrial Ca2+ uniporter MCU is essential for glucose-induced ATP increases in pancreatic β-cells.
Volume: 7
Issue: 7
Pages: e39722
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Publication
37363724 | J:337534
 
First Author: Fernandez Garcia E
Year: 2023
Journal: Front Cell Dev Biol
Title: The mitochondrial Ca(2+) channel MCU is critical for tumor growth by supporting cell cycle progression and proliferation.
Volume: 11
Pages: 1082213
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Publication
26828201 | J:240084
First Author: Márkus NM
Year: 2016
Journal: PLoS One
Title: Expression of mRNA Encoding Mcu and Other Mitochondrial Calcium Regulatory Genes Depends on Cell Type, Neuronal Subtype, and Ca2+ Signaling.
Volume: 11
Issue: 2
Pages: e0148164
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Publication
32350566 | J:294913
First Author: Georgiadou E
Year: 2020
Journal: Diabetologia
Title: The pore-forming subunit MCU of the mitochondrial Ca2+ uniporter is required for normal glucose-stimulated insulin secretion in vitro and in vivo in mice.
Volume: 63
Issue: 7
Pages: 1368-1381
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Publication
24296416 | J:208181
First Author: Herzig S
Year: 2013
Journal: Nat Cell Biol
Title: Life without the mitochondrial calcium uniporter.
Volume: 15
Issue: 12
Pages: 1398-400
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Publication
26119731 | J:224856
First Author: Luongo TS
Year: 2015
Journal: Cell Rep
Title: The Mitochondrial Calcium Uniporter Matches Energetic Supply with Cardiac Workload during Stress and Modulates Permeability Transition.
Volume: 12
Issue: 1
Pages: 23-34
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Publication
26057074 | J:225748
 
First Author: Holmström KM
Year: 2015
Journal: J Mol Cell Cardiol
Title: Assessment of cardiac function in mice lacking the mitochondrial calcium uniporter.
Volume: 85
Pages: 178-82
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Publication
25603276 | J:219717
 
First Author: Wu Y
Year: 2015
Journal: Nat Commun
Title: The mitochondrial uniporter controls fight or flight heart rate increases.
Volume: 6
Pages: 6081
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Publication
30615880 | J:295150
 
First Author: Altamimi TR
Year: 2019
Journal: J Mol Cell Cardiol
Title: Cardiac-specific deficiency of the mitochondrial calcium uniporter augments fatty acid oxidation and functional reserve.
Volume: 127
Pages: 223-231
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Publication
39153480 | J:353781
     
First Author: LaMoia TE
Year: 2024
Journal: Cell Metab
Title: Cytosolic calcium regulates hepatic mitochondrial oxidation, intrahepatic lipolysis, and gluconeogenesis via CAMKII activation.
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35766269 | J:327441
First Author: Damacena de Angelis C
Year: 2022
Journal: J Am Heart Assoc
Title: Sex-Specific Differences in Endothelial Function Are Driven by Divergent Mitochondrial Ca2+ Handling.
Volume: 11
Issue: 13
Pages: e023912
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Publication
30154242 | J:272829
First Author: Hamilton J
Year: 2018
Journal: J Biol Chem
Title: Deletion of mitochondrial calcium uniporter incompletely inhibits calcium uptake and induction of the permeability transition pore in brain mitochondria.
Volume: 293
Issue: 40
Pages: 15652-15663
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Publication
31881218 | J:283369
 
First Author: Ji SG
Year: 2020
Journal: Exp Neurol
Title: Zn2+ entry through the mitochondrial calcium uniporter is a critical contributor to mitochondrial dysfunction and neurodegeneration.
Volume: 325
Pages: 113161
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32094224 | J:286817
First Author: Szibor M
Year: 2020
Journal: J Biol Chem
Title: Cytosolic, but not matrix, calcium is essential for adjustment of mitochondrial pyruvate supply.
Volume: 295
Issue: 14
Pages: 4383-4397
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28351840 | J:247842
First Author: Gu L
Year: 2017
Journal: FASEB J
Title: Macrophages utilize the mitochondrial calcium uniporter for profibrotic polarization.
Volume: 31
Issue: 7
Pages: 3072-3083
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Publication
32745471 | J:301248
 
First Author: Holman SP
Year: 2020
Journal: Exp Neurol
Title: Neuronal mitochondrial calcium uniporter deficiency exacerbates axonal injury and suppresses remyelination in mice subjected to experimental autoimmune encephalomyelitis.
Volume: 333
Pages: 113430
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Publication
32516955 | J:304203
 
First Author: Chvanov M
Year: 2020
Journal: Cells
Title: Knockout of the Mitochondrial Calcium Uniporter Strongly Suppresses Stimulus-Metabolism Coupling in Pancreatic Acinar Cells but Does Not Reduce Severity of Experimental Acute Pancreatitis.
Volume: 9
Issue: 6
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Publication
33958614 | J:316339
First Author: Manikandan M
Year: 2021
Journal: Sci Rep
Title: Mitochondrial calcium uniporter is essential for hearing and hair cell preservation in congenic FVB/NJ mice.
Volume: 11
Issue: 1
Pages: 9660
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Publication
32703429 | J:302417
First Author: Zhang B
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Cyclophilin D counterbalances mitochondrial calcium uniporter-mediated brain mitochondrial calcium uptake.
Volume: 529
Issue: 2
Pages: 314-320
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Publication
33238121 | J:300795
First Author: Seegren PV
Year: 2020
Journal: Cell Rep
Title: Mitochondrial Ca2+ Signaling Is an Electrometabolic Switch to Fuel Phagosome Killing.
Volume: 33
Issue: 8
Pages: 108411
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26119742 | J:224853
First Author: Kwong JQ
Year: 2015
Journal: Cell Rep
Title: The Mitochondrial Calcium Uniporter Selectively Matches Metabolic Output to Acute Contractile Stress in the Heart.
Volume: 12
Issue: 1
Pages: 15-22
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Publication
32994451 | J:296254
First Author: Bisbach CM
Year: 2020
Journal: Sci Rep
Title: Mitochondrial Calcium Uniporter (MCU) deficiency reveals an alternate path for Ca2+ uptake in photoreceptor mitochondria.
Volume: 10
Issue: 1
Pages: 16041
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35977541 | J:329297
First Author: Xue K
Year: 2022
Journal: Cell Metab
Title: The mitochondrial calcium uniporter engages UCP1 to form a thermoporter that promotes thermogenesis.
Volume: 34
Issue: 9
Pages: 1325-1341.e6
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27429220 | J:237118
First Author: Kwon SK
Year: 2016
Journal: PLoS Biol
Title: LKB1 Regulates Mitochondria-Dependent Presynaptic Calcium Clearance and Neurotransmitter Release Properties at Excitatory Synapses along Cortical Axons.
Volume: 14
Issue: 7
Pages: e1002516
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28273446 | J:250763
First Author: Paillard M
Year: 2017
Journal: Cell Rep
Title: Tissue-Specific Mitochondrial Decoding of Cytoplasmic Ca2+ Signals Is Controlled by the Stoichiometry of MICU1/2 and MCU.
Volume: 18
Issue: 10
Pages: 2291-2300
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32299299 | J:293201
First Author: Huo J
Year: 2020
Journal: Circ Res
Title: MCUb Induction Protects the Heart From Postischemic Remodeling.
Volume: 127
Issue: 3
Pages: 379-390
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Publication
33462436 | J:309187
First Author: Li T
Year: 2021
Journal: Nat Microbiol
Title: Listeria monocytogenes upregulates mitochondrial calcium signalling to inhibit LC3-associated phagocytosis as a survival strategy.
Volume: 6
Issue: 3
Pages: 366-379
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Publication
30917323 | J:284475
First Author: Tomar D
Year: 2019
Journal: Cell Rep
Title: Blockade of MCU-Mediated Ca2+ Uptake Perturbs Lipid Metabolism via PP4-Dependent AMPK Dephosphorylation.
Volume: 26
Issue: 13
Pages: 3709-3725.e7
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Publication
39121218 | J:353309
First Author: Lebas M
Year: 2024
Journal: Sci Adv
Title: Integrated single-cell RNA-seq analysis reveals mitochondrial calcium signaling as a modulator of endothelial-to-mesenchymal transition.
Volume: 10
Issue: 32
Pages: eadp6182
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Publication
31473487 | J:289898
 
First Author: Gu L
Year: 2019
Journal: Redox Biol
Title: Mitochondrial calcium uniporter regulates PGC-1α expression to mediate metabolic reprogramming in pulmonary fibrosis.
Volume: 26
Pages: 101307
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34987384 | J:317692
 
First Author: Wu H
Year: 2021
Journal: Front Pharmacol
Title: Genetic Ablation of the Mitochondrial Calcium Uniporter (MCU) Does not Impair T Cell-Mediated Immunity In Vivo.
Volume: 12
Pages: 734078
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Publication
34497331 | J:359921
First Author: Joseph LC
Year: 2021
Journal: Sci Rep
Title: The mitochondrial calcium uniporter promotes arrhythmias caused by high-fat diet.
Volume: 11
Issue: 1
Pages: 17808
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Publication
37061004 | J:336574
First Author: Ashok D
Year: 2023
Journal: J Biol Chem
Title: Mitochondrial membrane potential instability on reperfusion after ischemia does not depend on mitochondrial Ca(2+) uptake.
Volume: 299
Issue: 6
Pages: 104708
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Publication
34499925 | J:314266
First Author: Yoast RE
Year: 2021
Journal: J Biol Chem
Title: The Mitochondrial Ca2+ uniporter is a central regulator of interorganellar Ca2+ transfer and NFAT activation.
Volume: 297
Issue: 4
Pages: 101174
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Publication
31722597 | J:300196
First Author: Bas-Orth C
Year: 2020
Journal: J Cereb Blood Flow Metab
Title: The mitochondrial calcium uniporter is crucial for the generation of fast cortical network rhythms.
Volume: 40
Issue: 11
Pages: 2225-2239
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Publication
30429366 | J:288725
 
First Author: Kwong JQ
Year: 2018
Journal: JCI Insight
Title: The mitochondrial calcium uniporter underlies metabolic fuel preference in skeletal muscle.
Volume: 3
Issue: 22
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30232375 | J:277727
First Author: Gherardi G
Year: 2019
Journal: Cell Death Differ
Title: Loss of mitochondrial calcium uniporter rewires skeletal muscle metabolism and substrate preference.
Volume: 26
Issue: 2
Pages: 362-381
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33864812 | J:306700
   
First Author: Hamilton J
Year: 2021
Journal: J Biol Chem
Title: The effect of mitochondrial calcium uniporter and cyclophilin D knockout on resistance of brain mitochondria to Ca2+-induced damage.
Pages: 100669
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Publication
32017711 | J:287405
 
First Author: Liu JC
Year: 2020
Journal: JCI Insight
Title: EMRE is essential for mitochondrial calcium uniporter activity in a mouse model.
Volume: 5
Issue: 4
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Publication
30158529 | J:266097
First Author: Shanmughapriya S
Year: 2018
Journal: Nat Commun
Title: FOXD1-dependent MICU1 expression regulates mitochondrial activity and cell differentiation.
Volume: 9
Issue: 1
Pages: 3449
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23409044 | J:196299
First Author: Plovanich M
Year: 2013
Journal: PLoS One
Title: MICU2, a paralog of MICU1, resides within the mitochondrial uniporter complex to regulate calcium handling.
Volume: 8
Issue: 2
Pages: e55785
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Publication
37230379 | J:349738
 
First Author: Chapoy Villanueva H
Year: 2023
Journal: J Mol Cell Cardiol
Title: Distinct effects of cardiac mitochondrial calcium uniporter inactivation via EMRE deletion in the short and long term.
Volume: 181
Pages: 33-45
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37848124 | J:358289
 
First Author: Hu J
Year: 2023
Journal: Toxicol Appl Pharmacol
Title: The mitochondrial calcium uniporter mediates mitochondrial Fe(2+) uptake and hepatotoxicity after acetaminophen.
Volume: 479
Pages: 116722
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Publication
38199601 | J:352263
 
First Author: Jia M
Year: 2024
Journal: Mol Metab
Title: Deletion of the mitochondrial calcium uniporter in adipose tissue promotes energy expenditure and alleviates diet-induced obesity.
Volume: 80
Pages: 101873
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38514795 | J:346444
First Author: Bround MJ
Year: 2024
Journal: Sci Rep
Title: MCU-independent Ca(2+) uptake mediates mitochondrial Ca(2+) overload and necrotic cell death in a mouse model of Duchenne muscular dystrophy.
Volume: 14
Issue: 1
Pages: 6751
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Publication
35733245 | J:333473
First Author: Dong H
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Mitochondrial calcium uniporter promotes phagocytosis-dependent activation of the NLRP3 inflammasome.
Volume: 119
Issue: 26
Pages: e2123247119
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29599132 | J:285151
First Author: Nguyen EK
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: CaMKII (Ca2+/Calmodulin-Dependent Kinase II) in Mitochondria of Smooth Muscle Cells Controls Mitochondrial Mobility, Migration, and Neointima Formation.
Volume: 38
Issue: 6
Pages: 1333-1345
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34677619 | J:332178
First Author: Tow BD
Year: 2022
Journal: Cardiovasc Res
Title: SR-Mitochondria Crosstalk Shapes Ca Signalling to Impact Pathophenotype in Disease Models Marked by Dysregulated Intracellular Ca Release.
Volume: 118
Issue: 13
Pages: 2819-2832
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25737585 | J:259457
First Author: Shanmughapriya S
Year: 2015
Journal: Sci Signal
Title: Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU.
Volume: 8
Issue: 366
Pages: ra23
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24212091 | J:208297
First Author: Pan X
Year: 2013
Journal: Nat Cell Biol
Title: The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter.
Volume: 15
Issue: 12
Pages: 1464-72
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32442661 | J:292634
 
First Author: Roman B
Year: 2020
Journal: J Mol Cell Cardiol
Title: Nuclear-mitochondrial communication involving miR-181c plays an important role in cardiac dysfunction during obesity.
Volume: 144
Pages: 87-96
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Publication
31042465 | J:289596
First Author: Flicker D
Year: 2019
Journal: Cell Rep
Title: Exploring the In Vivo Role of the Mitochondrial Calcium Uniporter in Brown Fat Bioenergetics.
Volume: 27
Issue: 5
Pages: 1364-1375.e5
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Publication
36274588 | J:334090
 
First Author: Devine MJ
Year: 2022
Journal: J Cell Sci
Title: Mitochondrial Ca2+ uniporter haploinsufficiency enhances long-term potentiation at hippocampal mossy fibre synapses.
Volume: 135
Issue: 22
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31586055 | J:281742
First Author: Lombardi AA
Year: 2019
Journal: Nat Commun
Title: Mitochondrial calcium exchange links metabolism with the epigenome to control cellular differentiation.
Volume: 10
Issue: 1
Pages: 4509
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33035451 | J:298361
First Author: Daw CC
Year: 2020
Journal: Cell
Title: Lactate Elicits ER-Mitochondrial Mg2+ Dynamics to Integrate Cellular Metabolism.
Volume: 183
Issue: 2
Pages: 474-489.e17
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35589699 | J:325615
First Author: Balderas E
Year: 2022
Journal: Nat Commun
Title: Mitochondrial calcium uniporter stabilization preserves energetic homeostasis during Complex I impairment.
Volume: 13
Issue: 1
Pages: 2769
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31501572 | J:281635
First Author: Fecher C
Year: 2019
Journal: Nat Neurosci
Title: Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity.
Volume: 22
Issue: 10
Pages: 1731-1742
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29694881 | J:272102
First Author: Nemani N
Year: 2018
Journal: Cell Rep
Title: MIRO-1 Determines Mitochondrial Shape Transition upon GPCR Activation and Ca2+ Stress.
Volume: 23
Issue: 4
Pages: 1005-1019
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33555254 | J:327583
   
First Author: Díaz-García CM
Year: 2021
Journal: Elife
Title: The distinct roles of calcium in rapid control of neuronal glycolysis and the tricarboxylic acid cycle.
Volume: 10
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26712344 | J:254215
First Author: Lu X
Year: 2016
Journal: Circ Res
Title: Individual Cardiac Mitochondria Undergo Rare Transient Permeability Transition Pore Openings.
Volume: 118
Issue: 5
Pages: 834-41
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36179023 | J:330006
First Author: Zampese E
Year: 2022
Journal: Sci Adv
Title: Ca2+ channels couple spiking to mitochondrial metabolism in substantia nigra dopaminergic neurons.
Volume: 8
Issue: 39
Pages: eabp8701
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34686324 | J:328736
First Author: Kosmach A
Year: 2021
Journal: Cell Rep
Title: Monitoring mitochondrial calcium and metabolism in the beating MCU-KO heart.
Volume: 37
Issue: 3
Pages: 109846
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37098122 | J:347330
First Author: Tomar D
Year: 2023
Journal: Sci Signal
Title: MICU1 regulates mitochondrial cristae structure and function independently of the mitochondrial Ca(2+) uniporter channel.
Volume: 16
Issue: 782
Pages: eabi8948
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37976157 | J:344737
First Author: Huo J
Year: 2023
Journal: Cell Rep
Title: MCUb is an inducible regulator of calcium-dependent mitochondrial metabolism and substrate utilization in muscle.
Volume: 42
Issue: 11
Pages: 113465
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Publication
23884415 | J:203542
First Author: Canalis E
Year: 2013
Journal: J Biol Chem
Title: Notch signaling in osteocytes differentially regulates cancellous and cortical bone remodeling.
Volume: 288
Issue: 35
Pages: 25614-25
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30165576 | J:291530
First Author: Parks RJ
Year: 2019
Journal: Cardiovasc Res
Title: Cyclophilin D-mediated regulation of the permeability transition pore is altered in mice lacking the mitochondrial calcium uniporter.
Volume: 115
Issue: 2
Pages: 385-394
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28942921 | J:271994
First Author: Wang Y
Year: 2017
Journal: Cell
Title: Mitochondrial Fission Promotes the Continued Clearance of Apoptotic Cells by Macrophages.
Volume: 171
Issue: 2
Pages: 331-345.e22
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34507993 | J:310226
 
First Author: Valença-Pereira F
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: IL-6 enhances CD4 cell motility by sustaining mitochondrial Ca2+ through the noncanonical STAT3 pathway.
Volume: 118
Issue: 37
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35302860 | J:322729
First Author: Singh R
Year: 2022
Journal: Sci Adv
Title: Uncontrolled mitochondrial calcium uptake underlies the pathogenesis of neurodegeneration in MICU1-deficient mice and patients.
Volume: 8
Issue: 11
Pages: eabj4716
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Publication
37493331 | J:341543
First Author: Meng TG
Year: 2023
Journal: Adv Sci (Weinh)
Title: NLRP14 Safeguards Calcium Homeostasis via Regulating the K27 Ubiquitination of Nclx in Oocyte-to-Embryo Transition.
Volume: 10
Issue: 27
Pages: e2301940
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16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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18614015 | J:151002
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
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27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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