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Search results 1 to 100 out of 151 for Mdm4

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Category: Publication
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Type Details Score
Publication
6163388 | -
First Author: Mero M
Year: 1980
Journal: Ann Chir Gynaecol
Title: Serum immunoreactive trypsin and trypsin inhibitors during acute pancreatitis.
Volume: 69
Issue: 6
Pages: 251-5
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Publication
16511572 | -
First Author: Jin Y
Year: 2006
Journal: EMBO J
Title: 14-3-3gamma binds to MDMX that is phosphorylated by UV-activated Chk1, resulting in p53 activation.
Volume: 25
Issue: 6
Pages: 1207-18
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Publication
33688918 | J:343864
 
First Author: Qu J
Year: 2021
Journal: J Exp Med
Title: Targeting mechanosensitive MDM4 promotes lung fibrosis resolution in aged mice.
Volume: 218
Issue: 5
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Publication
23327795 | J:320712
First Author: Xiong S
Year: 2013
Journal: Chin J Cancer
Title: Mouse models of Mdm2 and Mdm4 and their clinical implications.
Volume: 32
Issue: 7
Pages: 371-5
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Publication
17533180 | J:137114
First Author: Xiong S
Year: 2007
Journal: Circulation
Title: Loss of Mdm4 results in p53-dependent dilated cardiomyopathy.
Volume: 115
Issue: 23
Pages: 2925-30
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Publication
22820643 | J:317304
First Author: Gembarska A
Year: 2012
Journal: Nat Med
Title: MDM4 is a key therapeutic target in cutaneous melanoma.
Volume: 18
Issue: 8
Pages: 1239-47
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Publication
17105817 | J:143668
First Author: Maetens M
Year: 2007
Journal: Blood
Title: Distinct roles of Mdm2 and Mdm4 in red cell production.
Volume: 109
Issue: 6
Pages: 2630-3
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Publication
17526734 | J:123661
First Author: Terzian T
Year: 2007
Journal: Mol Cell Biol
Title: Haploinsufficiency of Mdm2 and Mdm4 in tumorigenesis and development.
Volume: 27
Issue: 15
Pages: 5479-85
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Publication
18567799 | J:139880
First Author: Barboza JA
Year: 2008
Journal: Mol Cancer Res
Title: Mdm2 and Mdm4 loss regulates distinct p53 activities.
Volume: 6
Issue: 6
Pages: 947-54
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Publication
27925213 | J:241797
First Author: Xiong S
Year: 2017
Journal: J Pathol
Title: The p53 inhibitor Mdm4 cooperates with multiple genetic lesions in tumourigenesis.
Volume: 241
Issue: 4
Pages: 501-510
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Publication
32464196 | J:300508
 
First Author: Hilliard SA
Year: 2020
Journal: Mech Dev
Title: Mdm4 controls ureteric bud branching via regulation of p53 activity.
Volume: 163
Pages: 103616
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Publication
14712235 | J:88362
First Author: Steinman HA
Year: 2004
Journal: Oncogene
Title: Absence of p21 partially rescues Mdm4 loss and uncovers an antiproliferative effect of Mdm4 on cell growth.
Volume: 23
Issue: 1
Pages: 303-6
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Publication
26527653 | J:230519
First Author: Tashakori M
Year: 2016
Journal: Mol Cancer Res
Title: p53 Activity Dominates That of p73 upon Mdm4 Loss in Development and Tumorigenesis.
Volume: 14
Issue: 1
Pages: 56-65
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Publication
24285179 | J:318847
First Author: Pellegrino R
Year: 2014
Journal: Hepatology
Title: EEF1A2 inactivates p53 by way of PI3K/AKT/mTOR-dependent stabilization of MDM4 in hepatocellular carcinoma.
Volume: 59
Issue: 5
Pages: 1886-99
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Publication
8895579 | J:36053
First Author: Shvarts A
Year: 1996
Journal: EMBO J
Title: MDMX: a novel p53-binding protein with some functional properties of MDM2.
Volume: 15
Issue: 19
Pages: 5349-57
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Publication
19371999 | J:149219
First Author: Valentin-Vega YA
Year: 2009
Journal: Differentiation
Title: Mdm4 loss in the intestinal epithelium leads to compartmentalized cell death but no tissue abnormalities.
Volume: 77
Issue: 5
Pages: 442-9
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Publication
22262167 | J:318094
First Author: Yang H
Year: 2012
Journal: Cell Cycle
Title: Downregulation of Mdm2 and Mdm4 enhances viral gene expression during adenovirus infection.
Volume: 11
Issue: 3
Pages: 582-93
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Publication
19521340 | J:150846
First Author: Mancini F
Year: 2009
Journal: EMBO J
Title: MDM4 (MDMX) localizes at the mitochondria and facilitates the p53-mediated intrinsic-apoptotic pathway.
Volume: 28
Issue: 13
Pages: 1926-39
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Publication
16492744 | J:120591
First Author: Francoz S
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating and quiescent cells in vivo.
Volume: 103
Issue: 9
Pages: 3232-7
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Publication
16027727 | J:103425
First Author: Steinman HA
Year: 2005
Journal: Oncogene
Title: Rescue of Mdm4-deficient mice by Mdm2 reveals functional overlap of Mdm2 and Mdm4 in development.
Volume: 24
Issue: 53
Pages: 7935-40
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Publication
16492743 | J:107178
First Author: Xiong S
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Synergistic roles of Mdm2 and Mdm4 for p53 inhibition in central nervous system development.
Volume: 103
Issue: 9
Pages: 3226-31
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Publication
30012555 | J:272583
First Author: Van Alstyne M
Year: 2018
Journal: Genes Dev
Title: Dysregulation of Mdm2 and Mdm4 alternative splicing underlies motor neuron death in spinal muscular atrophy.
Volume: 32
Issue: 15-16
Pages: 1045-1059
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Publication
12101245 | J:77907
First Author: Migliorini D
Year: 2002
Journal: Mol Cell Biol
Title: Mdm4 (Mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development.
Volume: 22
Issue: 15
Pages: 5527-38
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Publication
20697359 | J:170004
First Author: Giglio S
Year: 2010
Journal: Oncogene
Title: Regulation of MDM4 (MDMX) function by p76(MDM2): a new facet in the control of p53 activity.
Volume: 29
Issue: 44
Pages: 5935-45
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Publication
20855528 | J:317403
First Author: De Clercq S
Year: 2010
Journal: Mol Cell Biol
Title: Widespread overexpression of epitope-tagged Mdm4 does not accelerate tumor formation in vivo.
Volume: 30
Issue: 22
Pages: 5394-405
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23474762 | J:212378
First Author: Fang M
Year: 2014
Journal: Oncogene
Title: Mdm4 loss in mice expressing a p53 hypomorph alters tumor spectrum without improving survival.
Volume: 33
Issue: 10
Pages: 1336-9
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16616333 | J:108183
First Author: Toledo F
Year: 2006
Journal: Cancer Cell
Title: A mouse p53 mutant lacking the proline-rich domain rescues Mdm4 deficiency and provides insight into the Mdm2-Mdm4-p53 regulatory network.
Volume: 9
Issue: 4
Pages: 273-85
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Publication
25088193 | J:222536
First Author: Bardot B
Year: 2015
Journal: Oncogene
Title: Mice engineered for an obligatory Mdm4 exon skipping express higher levels of the Mdm4-S isoform but exhibit increased p53 activity.
Volume: 34
Issue: 22
Pages: 2943-8
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Publication
15361844 | J:93838
First Author: Iwakuma T
Year: 2004
Journal: Oncogene
Title: Mutation at p53 serine 389 does not rescue the embryonic lethality in mdm2 or mdm4 null mice.
Volume: 23
Issue: 46
Pages: 7644-50
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Publication
22821713 | J:188490
First Author: Zhang Q
Year: 2012
Journal: J Pathol
Title: Synergistic regulation of p53 by Mdm2 and Mdm4 is critical in cardiac endocardial cushion morphogenesis during heart development.
Volume: 228
Issue: 3
Pages: 416-28
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Publication
21730132 | J:174368
First Author: Pant V
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability.
Volume: 108
Issue: 29
Pages: 11995-2000
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Publication
24013503 | J:201152
First Author: Bezzi M
Year: 2013
Journal: Genes Dev
Title: Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery.
Volume: 27
Issue: 17
Pages: 1903-16
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Publication
25961923 | J:346784
First Author: Mancini F
Year: 2016
Journal: Oncogene
Title: MDM4/HIPK2/p53 cytoplasmic assembly uncovers coordinated repression of molecules with anti-apoptotic activity during early DNA damage response.
Volume: 35
Issue: 2
Pages: 228-40
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Publication
- | J:272830
     
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for isla_nublar.
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- | J:265262
     
First Author: Zhong X
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for sun_island.
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20736370 | J:164225
First Author: Xiong S
Year: 2010
Journal: Cancer Res
Title: Spontaneous tumorigenesis in mice overexpressing the p53-negative regulator Mdm4.
Volume: 70
Issue: 18
Pages: 7148-54
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17128209 | J:120252
First Author: Toledo F
Year: 2006
Journal: Nat Rev Cancer
Title: Regulating the p53 pathway: in vitro hypotheses, in vivo veritas.
Volume: 6
Issue: 12
Pages: 909-23
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28460439 | J:256595
First Author: Pant V
Year: 2017
Journal: Oncotarget
Title: Tumorigenesis promotes Mdm4-S overexpression.
Volume: 8
Issue: 16
Pages: 25837-25847
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20962274 | J:166152
First Author: Slee EA
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Phosphorylation of Ser312 contributes to tumor suppression by p53 in vivo.
Volume: 107
Issue: 45
Pages: 19479-84
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17018606 | J:113394
First Author: Chandler DS
Year: 2006
Journal: Cancer Res
Title: Genotoxic stress induces coordinately regulated alternative splicing of the p53 modulators MDM2 and MDM4.
Volume: 66
Issue: 19
Pages: 9502-8
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Publication
16729027 | J:132251
First Author: Boesten LS
Year: 2006
Journal: Cell Death Differ
Title: Mdm2, but not Mdm4, protects terminally differentiated smooth muscle cells from p53-mediated caspase-3-independent cell death.
Volume: 13
Issue: 12
Pages: 2089-98
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Publication
25144937 | J:223276
 
First Author: Xiong X
Year: 2014
Journal: Elife
Title: Ribosomal protein S27-like is a physiological regulator of p53 that suppresses genomic instability and tumorigenesis.
Volume: 3
Pages: e02236
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30807606 | J:273775
First Author: Wakasugi T
Year: 2019
Journal: PLoS One
Title: Role of smooth muscle cell p53 in pulmonary arterial hypertension.
Volume: 14
Issue: 2
Pages: e0212889
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Publication
33667384 | J:305020
First Author: Ueda K
Year: 2021
Journal: Cancer Cell
Title: MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism.
Volume: 39
Issue: 4
Pages: 529-547.e7
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Publication
27364741 | J:235222
First Author: Livera G
Year: 2016
Journal: FEBS Lett
Title: Loss of oocytes due to conditional ablation of Murine double minute 2 (Mdm2) gene is p53-dependent and results in female sterility.
Volume: 590
Issue: 16
Pages: 2566-74
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11528400 | J:71532
First Author: Parant J
Year: 2001
Journal: Nat Genet
Title: Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53.
Volume: 29
Issue: 1
Pages: 92-5
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Publication
25981963 | J:242745
First Author: Joshi Y
Year: 2015
Journal: Brain
Title: The MDM4/MDM2-p53-IGF1 axis controls axonal regeneration, sprouting and functional recovery after CNS injury.
Volume: 138
Issue: Pt 7
Pages: 1843-62
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27912078 | J:240039
First Author: Zhang CX
Year: 2017
Journal: Am J Pathol
Title: Mouse Double Minute 2 Actively Suppresses p53 Activity in Oocytes during Mouse Folliculogenesis.
Volume: 187
Issue: 2
Pages: 339-351
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16354690 | J:104114
First Author: Grier JD
Year: 2006
Journal: Mol Cell Biol
Title: Tissue-specific differences of p53 inhibition by Mdm2 and Mdm4.
Volume: 26
Issue: 1
Pages: 192-8
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14695178 | J:87065
First Author: Chavez-Reyes A
Year: 2003
Journal: Cancer Res
Title: Switching mechanisms of cell death in mdm2- and mdm4-null mice by deletion of p53 downstream targets.
Volume: 63
Issue: 24
Pages: 8664-9
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28049824 | J:239540
First Author: Zhang G
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: p53 pathway is involved in cell competition during mouse embryogenesis.
Volume: 114
Issue: 3
Pages: 498-503
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37612280 | J:339368
First Author: Yao F
Year: 2023
Journal: Cell Death Dis
Title: Deletion of ARGLU1 causes global defects in alternative splicing in vivo and mouse cortical malformations primarily via apoptosis.
Volume: 14
Issue: 8
Pages: 543
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15916963 | J:197517
First Author: Meulmeester E
Year: 2005
Journal: Mol Cell
Title: Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2.
Volume: 18
Issue: 5
Pages: 565-76
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11404026 | J:70147
First Author: Parant JM
Year: 2001
Journal: Gene
Title: Organization, expression, and localization of the murine mdmx gene and pseudogene.
Volume: 270
Issue: 1-2
Pages: 277-83
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23303139 | J:193502
First Author: Wade M
Year: 2013
Journal: Nat Rev Cancer
Title: MDM2, MDMX and p53 in oncogenesis and cancer therapy.
Volume: 13
Issue: 2
Pages: 83-96
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26477779 | J:318332
 
First Author: Colacurcio DJ
Year: 2015
Journal: Neurosci Lett
Title: Caspase-dependent degradation of MDMx/MDM4 cell cycle regulatory protein in amyloid β-induced neuronal damage.
Volume: 609
Pages: 182-8
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32511789 | J:293949
First Author: Huang Q
Year: 2020
Journal: EMBO J
Title: MDMX inhibits casein kinase 1α activity and stimulates Wnt signaling.
Volume: 39
Issue: 14
Pages: e104410
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9226370 | J:41655
First Author: Shvarts A
Year: 1997
Journal: Genomics
Title: Isolation and identification of the human homolog of a new p53-binding protein, Mdmx.
Volume: 43
Issue: 1
Pages: 34-42
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24190973 | J:207681
First Author: He G
Year: 2014
Journal: Mol Cell Biol
Title: AMP-activated protein kinase induces p53 by phosphorylating MDMX and inhibiting its activity.
Volume: 34
Issue: 2
Pages: 148-57
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18039860 | J:132640
First Author: Matijasevic Z
Year: 2008
Journal: Mol Cell Biol
Title: MdmX promotes bipolar mitosis to suppress transformation and tumorigenesis in p53-deficient cells and mice.
Volume: 28
Issue: 4
Pages: 1265-73
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12036937 | J:77030
First Author: Finch RA
Year: 2002
Journal: Cancer Res
Title: mdmx is a negative regulator of p53 activity in vivo.
Volume: 62
Issue: 11
Pages: 3221-5
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16543935 | J:126382
First Author: Marine JC
Year: 2006
Journal: Cell Death Differ
Title: Keeping p53 in check: essential and synergistic functions of Mdm2 and Mdm4.
Volume: 13
Issue: 6
Pages: 927-34
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29709619 | J:277525
 
First Author: Si S
Year: 2018
Journal: Exp Hematol
Title: Hematopoietic insults damage bone marrow niche by activating p53 in vascular endothelial cells.
Volume: 63
Pages: 41-51.e1
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29581299 | J:261424
First Author: Huang Q
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: MDMX acidic domain inhibits p53 DNA binding in vivo and regulates tumorigenesis.
Volume: 115
Issue: 15
Pages: E3368-E3377
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29540569 | J:261078
First Author: Kuser-Abali G
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: An EZH2-mediated epigenetic mechanism behind p53-dependent tissue sensitivity to DNA damage.
Volume: 115
Issue: 13
Pages: 3452-3457
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29484110 | J:286053
First Author: Kon N
Year: 2018
Journal: Oncotarget
Title: Inhibition of Mdmx (Mdm4) in vivo induces anti-obesity effects.
Volume: 9
Issue: 7
Pages: 7282-7297
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11978988 | J:76602
First Author: Yao R
Year: 2001
Journal: Cytogenet Cell Genet
Title: Chromosome mapping and sequence variation of the murine Ras effector gene Nore1.
Volume: 95
Issue: 1-2
Pages: 126-8
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15865931 | J:98176
First Author: Marine JC
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Mdmx as an essential regulator of p53 activity.
Volume: 331
Issue: 3
Pages: 750-60
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25117711 | J:214218
First Author: Tollini LA
Year: 2014
Journal: Cancer Cell
Title: Regulation of p53 by Mdm2 E3 ligase function is dispensable in embryogenesis and development, but essential in response to DNA damage.
Volume: 26
Issue: 2
Pages: 235-47
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21674502 | J:174216
First Author: Terzian T
Year: 2011
Journal: J Pathol
Title: Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models.
Volume: 224
Issue: 4
Pages: 540-52
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21852537 | J:174671
First Author: Garcia D
Year: 2011
Journal: Genes Dev
Title: Validation of MdmX as a therapeutic target for reactivating p53 in tumors.
Volume: 25
Issue: 16
Pages: 1746-57
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30790589 | J:276227
 
First Author: Yokoyama M
Year: 2019
Journal: J Mol Cell Cardiol
Title: p53 plays a crucial role in endothelial dysfunction associated with hyperglycemia and ischemia.
Volume: 129
Pages: 105-117
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24857662 | J:211787
First Author: Yokoyama M
Year: 2014
Journal: Cell Rep
Title: Inhibition of endothelial p53 improves metabolic abnormalities related to dietary obesity.
Volume: 7
Issue: 5
Pages: 1691-1703
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29123033 | J:256782
First Author: Tian H
Year: 2017
Journal: J Biol Chem
Title: Inactivation of the MDM2 RING domain enhances p53 transcriptional activity in mice.
Volume: 292
Issue: 52
Pages: 21614-21622
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23770245 | J:199308
First Author: Simeonova I
Year: 2013
Journal: Cell Rep
Title: Mutant mice lacking the p53 C-terminal domain model telomere syndromes.
Volume: 3
Issue: 6
Pages: 2046-58
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33277368 | J:303986
First Author: Yang J
Year: 2021
Journal: Cancer Res
Title: MDMX Recruits UbcH5c to Facilitate MDM2 E3 Ligase Activity and Subsequent p53 Degradation In Vivo.
Volume: 81
Issue: 4
Pages: 898-909
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27568562 | J:239019
First Author: Carr MI
Year: 2016
Journal: Cell Rep
Title: Mdm2 Phosphorylation Regulates Its Stability and Has Contrasting Effects on Oncogene and Radiation-Induced Tumorigenesis.
Volume: 16
Issue: 10
Pages: 2618-2629
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19573810 | J:150341
First Author: Wang YV
Year: 2009
Journal: Cancer Cell
Title: Increased radioresistance and accelerated B cell lymphomas in mice with Mdmx mutations that prevent modifications by DNA-damage-activated kinases.
Volume: 16
Issue: 1
Pages: 33-43
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17823617 | J:142171
First Author: Benosman S
Year: 2007
Journal: Cell Death Differ
Title: Multiple neurotoxic stresses converge on MDMX proteolysis to cause neuronal apoptosis.
Volume: 14
Issue: 12
Pages: 2047-57
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26565902 | J:228954
First Author: He XY
Year: 2015
Journal: Cell Rep
Title: p53 in the Myeloid Lineage Modulates an Inflammatory Microenvironment Limiting Initiation and Invasion of Intestinal Tumors.
Volume: 13
Issue: 5
Pages: 888-97
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21730163 | J:174359
First Author: Huang L
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: The p53 inhibitors MDM2/MDMX complex is required for control of p53 activity in vivo.
Volume: 108
Issue: 29
Pages: 12001-6
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Publication
23973961 | J:201057
First Author: Pant V
Year: 2013
Journal: Genes Dev
Title: The p53-Mdm2 feedback loop protects against DNA damage by inhibiting p53 activity but is dispensable for p53 stability, development, and longevity.
Volume: 27
Issue: 17
Pages: 1857-67
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22666487 | J:187290
First Author: Clegg HV
Year: 2012
Journal: PLoS One
Title: Mdm2 RING mutation enhances p53 transcriptional activity and p53-p300 interaction.
Volume: 7
Issue: 5
Pages: e38212
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25263199 | J:217191
First Author: Zhang Y
Year: 2014
Journal: Dev Biol
Title: Aberrant activation of p53 due to loss of MDM2 or MDMX causes early lens dysmorphogenesis.
Volume: 396
Issue: 1
Pages: 19-30
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25457166 | J:219506
First Author: Kim S
Year: 2014
Journal: Mol Cell
Title: PRMT5 protects genomic integrity during global DNA demethylation in primordial germ cells and preimplantation embryos.
Volume: 56
Issue: 4
Pages: 564-79
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25976245 | J:223310
First Author: Crespo I
Year: 2015
Journal: Am J Pathol
Title: Molecular and Genomic Alterations in Glioblastoma Multiforme.
Volume: 185
Issue: 7
Pages: 1820-33
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