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Search results 1 to 100 out of 1007 for Pax2

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Category: Publication
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Type Details Score
Publication
11807024 | J:73896
First Author: Pfeffer PL
Year: 2002
Journal: Development
Title: The activation and maintenance of Pax2 expression at the mid-hindbrain boundary is controlled by separate enhancers.
Volume: 129
Issue: 2
Pages: 307-18
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Publication
12435636 | J:80208
First Author: Bouchard M
Year: 2002
Journal: Genes Dev
Title: Nephric lineage specification by Pax2 and Pax8.
Volume: 16
Issue: 22
Pages: 2958-70
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Publication
16609680 | J:136502
First Author: Hueber PA
Year: 2006
Journal: Kidney Int
Title: PAX2 inactivation enhances cisplatin-induced apoptosis in renal carcinoma cells.
Volume: 69
Issue: 7
Pages: 1139-45
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Publication
16368682 | J:112694
First Author: Torban E
Year: 2006
Journal: J Biol Chem
Title: PAX2 activates WNT4 expression during mammalian kidney development.
Volume: 281
Issue: 18
Pages: 12705-12
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Publication
9473325 | J:45929
First Author: Otteson DC
Year: 1998
Journal: Dev Biol
Title: Pax2 expression and retinal morphogenesis in the normal and Krd mouse.
Volume: 193
Issue: 2
Pages: 209-24
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Publication
10466411 | J:56640
First Author: Eccles MR
Year: 1999
Journal: Clin Genet
Title: Renal-coloboma syndrome: a multi-system developmental disorder caused by PAX2 mutations.
Volume: 56
Issue: 1
Pages: 1-9
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Publication
9159136 | J:40910
First Author: Urbánek P
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Cooperation of Pax2 and Pax5 in midbrain and cerebellum development.
Volume: 94
Issue: 11
Pages: 5703-8
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Publication
17925232 | J:128440
First Author: Patel SR
Year: 2007
Journal: Dev Cell
Title: The BRCT-domain containing protein PTIP links PAX2 to a histone H3, lysine 4 methyltransferase complex.
Volume: 13
Issue: 4
Pages: 580-92
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Publication
17082250 | J:117762
First Author: Stayner C
Year: 2006
Journal: Hum Mol Genet
Title: Pax2 gene dosage influences cystogenesis in autosomal dominant polycystic kidney disease.
Volume: 15
Issue: 24
Pages: 3520-8
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Publication
1977575 | J:20056
First Author: Nornes HO
Year: 1990
Journal: Development
Title: Spatially and temporally restricted expression of Pax2 during murine neurogenesis.
Volume: 109
Issue: 4
Pages: 797-809
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Publication
10934015 | J:63683
First Author: Bouchard M
Year: 2000
Journal: Development
Title: Functional equivalence of the transcription factors Pax2 and Pax5 in mouse development.
Volume: 127
Issue: 17
Pages: 3703-13
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Publication
15083520 | J:89784
First Author: Ohyama T
Year: 2004
Journal: Genesis
Title: Generation of Pax2-Cre mice by modification of a Pax2 bacterial artificial chromosome.
Volume: 38
Issue: 4
Pages: 195-9
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Publication
10908331 | J:69176
First Author: Lechner MS
Year: 2000
Journal: Nucleic Acids Res
Title: PTIP, a novel BRCT domain-containing protein interacts with Pax2 and is associated with active chromatin.
Volume: 28
Issue: 14
Pages: 2741-51
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Publication
10980123 | J:64394
First Author: Torban E
Year: 2000
Journal: Am J Pathol
Title: PAX2 suppresses apoptosis in renal collecting duct cells.
Volume: 157
Issue: 3
Pages: 833-42
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Publication
8951055 | J:36834
First Author: Torres M
Year: 1996
Journal: Development
Title: Pax2 contributes to inner ear patterning and optic nerve trajectory.
Volume: 122
Issue: 11
Pages: 3381-91
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Publication
14603255 | J:86661
First Author: Discenza MT
Year: 2003
Journal: Oncogene
Title: WT1 is a modifier of the Pax2 mutant phenotype: cooperation and interaction between WT1 and Pax2.
Volume: 22
Issue: 50
Pages: 8145-55
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Publication
15242798 | J:92326
First Author: Burton Q
Year: 2004
Journal: Dev Biol
Title: The role of Pax2 in mouse inner ear development.
Volume: 272
Issue: 1
Pages: 161-75
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Publication
33428890 | J:303632
 
First Author: Bosze B
Year: 2021
Journal: Dev Biol
Title: Multiple roles for Pax2 in the embryonic mouse eye.
Volume: 472
Pages: 18-29
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Publication
17881463 | J:145105
First Author: Murawski IJ
Year: 2007
Journal: Am J Physiol Renal Physiol
Title: Vesico-ureteric reflux and urinary tract development in the Pax2 1Neu+/- mouse.
Volume: 293
Issue: 5
Pages: F1736-45
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Publication
16672320 | J:129294
First Author: Dziarmaga A
Year: 2006
Journal: J Am Soc Nephrol
Title: Suppression of ureteric bud apoptosis rescues nephron endowment and adult renal function in Pax2 mutant mice.
Volume: 17
Issue: 6
Pages: 1568-75
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Publication
20727173 | J:163537
 
First Author: Bouchard M
Year: 2010
Journal: BMC Dev Biol
Title: Pax2 and Pax8 cooperate in mouse inner ear morphogenesis and innervation.
Volume: 10
Pages: 89
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Publication
17164400 | J:120768
First Author: Cohen T
Year: 2007
Journal: Am J Physiol Renal Physiol
Title: PAX2 is reactivated in urinary tract obstruction and partially protects collecting duct cells from programmed cell death.
Volume: 292
Issue: 4
Pages: F1267-73
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Publication
17314325 | J:120229
First Author: Narlis M
Year: 2007
Journal: J Am Soc Nephrol
Title: Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney.
Volume: 18
Issue: 4
Pages: 1121-9
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Publication
7835879 | J:20807
First Author: Keller SA
Year: 1994
Journal: Genomics
Title: Kidney and retinal defects (Krd), a transgene-induced mutation with a deletion of mouse chromosome 19 that includes the Pax2 locus.
Volume: 23
Issue: 2
Pages: 309-20
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Publication
32653558 | J:291402
 
First Author: Wei H
Year: 2020
Journal: Behav Brain Res
Title: Increased repetitive self-grooming occurs in Pax2 mutant mice generated using CRISPR/Cas9.
Volume: 393
Pages: 112803
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Publication
21731775 | J:174353
First Author: Boualia SK
Year: 2011
Journal: PLoS One
Title: Vesicoureteral reflux and other urinary tract malformations in mice compound heterozygous for Pax2 and Emx2.
Volume: 6
Issue: 6
Pages: e21529
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38482556 | J:352476
First Author: Cunanan J
Year: 2024
Journal: Am J Physiol Renal Physiol
Title: Mice with a Pax2 missense variant display impaired glomerular repair.
Volume: 326
Issue: 5
Pages: F704-F726
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Publication
10662641 | J:60092
First Author: Pfeffer PL
Year: 2000
Journal: Development
Title: Pax2 and homeodomain proteins cooperatively regulate a 435 bp enhancer of the mouse Pax5 gene at the midbrain-hindbrain boundary.
Volume: 127
Issue: 5
Pages: 1017-28
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Publication
12756174 | J:83532
First Author: Bäumer N
Year: 2003
Journal: Development
Title: Retinal pigmented epithelium determination requires the redundant activities of Pax2 and Pax6.
Volume: 130
Issue: 13
Pages: 2903-15
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Publication
15012626 | J:89465
First Author: Zaiko M
Year: 2004
Journal: Eur J Endocrinol
Title: Pax2 mutant mice display increased number and size of islets of Langerhans but no change in insulin and glucagon content.
Volume: 150
Issue: 3
Pages: 389-95
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Publication
17173889 | J:119142
First Author: Soukkarieh C
Year: 2007
Journal: Dev Biol
Title: Pax2 regulates neuronal-glial cell fate choice in the embryonic optic nerve.
Volume: 303
Issue: 2
Pages: 800-13
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Publication
19037705 | J:173744
First Author: Nakane A
Year: 2009
Journal: In Vitro Cell Dev Biol Anim
Title: Pax2 overexpression in embryoid bodies induces upregulation of integrin alpha8 and aquaporin-1.
Volume: 45
Issue: 1-2
Pages: 62-8
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Publication
18700968 | J:139696
 
First Author: Fotaki V
Year: 2008
Journal: BMC Dev Biol
Title: Newly identified patterns of Pax2 expression in the developing mouse forebrain.
Volume: 8
Pages: 79
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Publication
22677559 | J:316665
First Author: Qin S
Year: 2012
Journal: J Am Soc Nephrol
Title: c-Met and NF-κB-dependent overexpression of Wnt7a and -7b and Pax2 promotes cystogenesis in polycystic kidney disease.
Volume: 23
Issue: 8
Pages: 1309-18
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Publication
10587573 | J:59408
First Author: Porteous S
Year: 2000
Journal: Hum Mol Genet
Title: Primary renal hypoplasia in humans and mice with PAX2 mutations: evidence of increased apoptosis in fetal kidneys of Pax2(1Neu) +/- mutant mice.
Volume: 9
Issue: 1
Pages: 1-11
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Publication
7795640 | J:41679
First Author: Sanyanusin P
Year: 1995
Journal: Nat Genet
Title: Mutation of the PAX2 gene in a family with optic nerve colobomas, renal anomalies and vesicoureteral reflux.
Volume: 9
Issue: 4
Pages: 358-64
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Publication
10694420 | J:61157
First Author: Ostrom L
Year: 2000
Journal: Dev Biol
Title: Reduced Pax2 gene dosage increases apoptosis and slows the progression of renal cystic disease.
Volume: 219
Issue: 2
Pages: 250-8
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Publication
30144446 | J:268604
First Author: Lu M
Year: 2018
Journal: Exp Cell Res
Title: Pax2 is essential for proliferation and osteogenic differentiation of mouse mesenchymal stem cells via Runx2.
Volume: 371
Issue: 2
Pages: 342-352
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Publication
12756228 | J:83385
First Author: Weston CR
Year: 2003
Journal: Genes Dev
Title: JNK initiates a cytokine cascade that causes Pax2 expression and closure of the optic fissure.
Volume: 17
Issue: 10
Pages: 1271-80
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Publication
9112988 | J:39854
First Author: Green DG
Year: 1997
Journal: Invest Ophthalmol Vis Sci
Title: Electrophysiology and density of retinal neurons in mice with a mutation that includes the Pax2 locus.
Volume: 38
Issue: 5
Pages: 919-29
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Publication
17047028 | J:117753
First Author: Clarke JC
Year: 2006
Journal: Hum Mol Genet
Title: Regulation of c-Ret in the developing kidney is responsive to Pax2 gene dosage.
Volume: 15
Issue: 23
Pages: 3420-8
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Publication
20943750 | J:166924
First Author: Cross SH
Year: 2011
Journal: Hum Mol Genet
Title: The Opdc missense mutation of Pax2 has a milder than loss-of-function phenotype.
Volume: 20
Issue: 2
Pages: 223-34
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8970821 | J:37995
First Author: Rinkwitz-Brandt S
Year: 1996
Journal: Hear Res
Title: Regionalized expression of Nkx5-1, Nkx5-2, Pax2 and sek genes during mouse inner ear development.
Volume: 99
Issue: 1-2
Pages: 129-38
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Publication
11793341 | J:73497
First Author: Lawoko-Kerali G
Year: 2002
Journal: J Comp Neurol
Title: Expression of the transcription factors GATA3 and Pax2 during development of the mammalian inner ear.
Volume: 442
Issue: 4
Pages: 378-91
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Publication
11003833 | J:64590
First Author: Schwarz M
Year: 2000
Journal: Development
Title: Spatial specification of mammalian eye territories by reciprocal transcriptional repression of Pax2 and Pax6.
Volume: 127
Issue: 20
Pages: 4325-34
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Publication
11511678 | J:71108
First Author: Lozanoff S
Year: 2001
Journal: J Histochem Cytochem
Title: Immunohistochemical localization of Pax2 and associated proteins in the developing kidney of mice with renal hypoplasia.
Volume: 49
Issue: 9
Pages: 1081-97
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Publication
9439670 | J:45157
First Author: Tavassoli K
Year: 1997
Journal: Hum Genet
Title: Alternative splicing in PAX2 generates a new reading frame and an extended conserved coding region at the carboxy terminus.
Volume: 101
Issue: 3
Pages: 371-5
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Publication
22410172 | J:184878
First Author: Soofi A
Year: 2012
Journal: Dev Biol
Title: Two novel EGFP insertion alleles reveal unique aspects of Pax2 function in embryonic and adult kidneys.
Volume: 365
Issue: 1
Pages: 241-50
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Publication
19505455 | J:152817
First Author: Sehgal R
Year: 2009
Journal: Dev Biol
Title: BMP7 and SHH regulate Pax2 in mouse retinal astrocytes by relieving TLX repression.
Volume: 332
Issue: 2
Pages: 429-43
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Publication
25617721 | J:219797
First Author: Ranghini EJ
Year: 2015
Journal: Dev Biol
Title: Evidence for intermediate mesoderm and kidney progenitor cell specification by Pax2 and PTIP dependent mechanisms.
Volume: 399
Issue: 2
Pages: 296-305
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Publication
18634777 | J:142008
First Author: Huang M
Year: 2008
Journal: Dev Biol
Title: Ptf1a, Lbx1 and Pax2 coordinate glycinergic and peptidergic transmitter phenotypes in dorsal spinal inhibitory neurons.
Volume: 322
Issue: 2
Pages: 394-405
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Publication
22511595 | J:185279
First Author: Paces-Fessy M
Year: 2012
Journal: Hum Mol Genet
Title: Hnf1b and Pax2 cooperate to control different pathways in kidney and ureter morphogenesis.
Volume: 21
Issue: 14
Pages: 3143-55
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Publication
29370269 | J:257955
First Author: Patel D
Year: 2018
Journal: PLoS One
Title: The histone demethylase LSD1 regulates inner ear progenitor differentiation through interactions with Pax2 and the NuRD repressor complex.
Volume: 13
Issue: 1
Pages: e0191689
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Publication
32381599 | J:345452
First Author: Laszczyk AM
Year: 2020
Journal: J Am Soc Nephrol
Title: Pax2 and Pax8 Proteins Regulate Urea Transporters and Aquaporins to Control Urine Concentration in the Adult Kidney.
Volume: 31
Issue: 6
Pages: 1212-1225
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Publication
35645731 | J:325114
 
First Author: Serra I
Year: 2022
Journal: Front Mol Neurosci
Title: Tsc1 Haploinsufficiency Leads to Pax2 Dysregulation in the Developing Murine Cerebellum.
Volume: 15
Pages: 831687
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Publication
28535371 | J:241850
First Author: Naiman N
Year: 2017
Journal: Dev Cell
Title: Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development.
Volume: 41
Issue: 4
Pages: 349-365.e3
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Publication
8943028 | J:37055
First Author: Favor J
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: The mouse Pax2(1Neu) mutation is identical to a human PAX2 mutation in a family with renal-coloboma syndrome and results in developmental defects of the brain, ear, eye, and kidney.
Volume: 93
Issue: 24
Pages: 13870-5
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Publication
9409667 | J:88970
First Author: Burrill JD
Year: 1997
Journal: Development
Title: PAX2 is expressed in multiple spinal cord interneurons, including a population of EN1+ interneurons that require PAX6 for their development.
Volume: 124
Issue: 22
Pages: 4493-503
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Publication
16916509 | J:119574
First Author: Zou D
Year: 2006
Journal: Dev Biol
Title: Eya1 regulates the growth of otic epithelium and interacts with Pax2 during the development of all sensory areas in the inner ear.
Volume: 298
Issue: 2
Pages: 430-41
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11704761 | J:72984
First Author: Ye W
Year: 2001
Journal: Nat Neurosci
Title: Distinct regulators control the expression of the mid-hindbrain organizer signal FGF8.
Volume: 4
Issue: 12
Pages: 1175-81
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15064766 | J:90585
First Author: Cheng L
Year: 2004
Journal: Nat Neurosci
Title: Tlx3 and Tlx1 are post-mitotic selector genes determining glutamatergic over GABAergic cell fates.
Volume: 7
Issue: 5
Pages: 510-7
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Publication
15872005 | J:98482
First Author: Bouchard M
Year: 2005
Journal: Development
Title: Identification of Pax2-regulated genes by expression profiling of the mid-hindbrain organizer region.
Volume: 132
Issue: 11
Pages: 2633-43
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Publication
22984579 | J:192892
First Author: Saifudeen Z
Year: 2012
Journal: PLoS One
Title: A p53-Pax2 pathway in kidney development: implications for nephrogenesis.
Volume: 7
Issue: 9
Pages: e44869
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Publication
12117823 | J:77446
First Author: Wendl T
Year: 2002
Journal: Development
Title: Pax2.1 is required for the development of thyroid follicles in zebrafish.
Volume: 129
Issue: 15
Pages: 3751-60
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Publication
16216236 | J:104938
First Author: Pedersen A
Year: 2005
Journal: Dev Biol
Title: Lim 1 is required for nephric duct extension and ureteric bud morphogenesis.
Volume: 288
Issue: 2
Pages: 571-81
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23515312 | J:198381
First Author: Carbe C
Year: 2013
Journal: J Biol Chem
Title: An allelic series at the paired box gene 6 (Pax6) locus reveals the functional specificity of Pax genes.
Volume: 288
Issue: 17
Pages: 12130-41
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16319112 | J:104408
First Author: Grote D
Year: 2006
Journal: Development
Title: Pax 2/8-regulated Gata 3 expression is necessary for morphogenesis and guidance of the nephric duct in the developing kidney.
Volume: 133
Issue: 1
Pages: 53-61
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1977574 | J:10797
First Author: Dressler GR
Year: 1990
Journal: Development
Title: Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system.
Volume: 109
Issue: 4
Pages: 787-95
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11693299 | J:73206
First Author: Bard JB
Year: 2001
Journal: J Anat
Title: Early nephron formation in the developing mouse kidney.
Volume: 199
Issue: Pt 4
Pages: 385-92
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Publication
20221250 | J:159240
First Author: Alur RP
Year: 2010
Journal: PLoS Genet
Title: Papillorenal syndrome-causing missense mutations in PAX2/Pax2 result in hypomorphic alleles in mouse and human.
Volume: 6
Issue: 3
Pages: e1000870
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7856737 | J:172924
First Author: Eccles MR
Year: 1995
Journal: Am J Pathol
Title: Comparative in situ hybridization analysis of PAX2, PAX8, and WT1 gene transcription in human fetal kidney and Wilms' tumors.
Volume: 146
Issue: 1
Pages: 40-5
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16631587 | J:108896
First Author: Wagner KD
Year: 2006
Journal: Curr Biol
Title: An inducible mouse model for PAX2-dependent glomerular disease: insights into a complex pathogenesis.
Volume: 16
Issue: 8
Pages: 793-800
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Publication
16903854 | J:111533
First Author: Weisheit G
Year: 2006
Journal: Eur J Neurosci
Title: Postnatal development of the murine cerebellar cortex: formation and early dispersal of basket, stellate and Golgi neurons.
Volume: 24
Issue: 2
Pages: 466-78
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17785448 | J:129070
First Author: Gong KQ
Year: 2007
Journal: Mol Cell Biol
Title: A Hox-Eya-Pax complex regulates early kidney developmental gene expression.
Volume: 27
Issue: 21
Pages: 7661-8
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18083586 | J:172973
First Author: Alur RP
Year: 2008
Journal: J AAPOS
Title: Optic nerve axon number in mouse is regulated by PAX2.
Volume: 12
Issue: 2
Pages: 117-21
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10864462 | J:63194
First Author: Tsang TE
Year: 2000
Journal: Dev Biol
Title: Lim1 activity is required for intermediate mesoderm differentiation in the mouse embryo.
Volume: 223
Issue: 1
Pages: 77-90
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20171952 | J:172946
First Author: Mae S
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Combination of small molecules enhances differentiation of mouse embryonic stem cells into intermediate mesoderm through BMP7-positive cells.
Volume: 393
Issue: 4
Pages: 877-82
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9738017 | J:50071
First Author: Stayner CK
Year: 1998
Journal: J Biol Chem
Title: Cloning and characterization of the human PAX2 promoter.
Volume: 273
Issue: 39
Pages: 25472-9
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Publication
22669823 | J:185503
First Author: Yu CT
Year: 2012
Journal: Development
Title: COUP-TFII is essential for metanephric mesenchyme formation and kidney precursor cell survival.
Volume: 139
Issue: 13
Pages: 2330-9
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Publication
16735463 | J:172991
First Author: Dziarmaga A
Year: 2006
Journal: Am J Physiol Renal Physiol
Title: Neuronal apoptosis inhibitory protein is expressed in developing kidney and is regulated by PAX2.
Volume: 291
Issue: 4
Pages: F913-20
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Publication
16900517 | J:114449
First Author: Robledo RF
Year: 2006
Journal: Genesis
Title: Dlx5 and Dlx6 homeobox genes are required for specification of the mammalian vestibular apparatus.
Volume: 44
Issue: 9
Pages: 425-37
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Publication
30220628 | J:333402
First Author: Ihermann-Hella A
Year: 2018
Journal: Stem Cell Reports
Title: Dynamic MAPK/ERK Activity Sustains Nephron Progenitors through Niche Regulation and Primes Precursors for Differentiation.
Volume: 11
Issue: 4
Pages: 912-928
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Publication
22725947 | J:317543
First Author: Stayner C
Year: 2012
Journal: Nephrology (Carlton)
Title: Rapamycin-mediated suppression of renal cyst expansion in del34 Pkd1-/- mutant mouse embryos: an investigation of the feasibility of renal cyst prevention in the foetus.
Volume: 17
Issue: 8
Pages: 739-47
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Publication
10490025 | J:57538
First Author: Broccoli V
Year: 1999
Journal: Nature
Title: The caudal limit of Otx2 expression positions the isthmic organizer.
Volume: 401
Issue: 6749
Pages: 164-8
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11804780 | J:74492
First Author: Heanue TA
Year: 2002
Journal: Mech Dev
Title: Dach1, a vertebrate homologue of Drosophila dachshund, is expressed in the developing eye and ear of both chick and mouse and is regulated independently of Pax and Eya genes.
Volume: 111
Issue: 1-2
Pages: 75-87
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First Author: Surace EM
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Journal: Invest Ophthalmol Vis Sci
Title: Expression pattern of the ocular albinism type 1 (Oa1) gene in the murine retinal pigment epithelium.
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First Author: Washausen S
Year: 2017
Journal: Brain Struct Funct
Title: Pax2/Pax8-defined subdomains and the occurrence of apoptosis in the posterior placodal area of mice.
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Title: The Key Transcription Factor Expression in the Developing Vestibular and Auditory Sensory Organs: A Comprehensive Comparison of Spatial and Temporal Patterns.
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Journal: Dev Biol
Title: Abnormal cerebellar development and Purkinje cell defects in Lgl1-Pax2 conditional knockout mice.
Volume: 395
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First Author: Pan N
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Journal: Hear Res
Title: Conditional deletion of Atoh1 using Pax2-Cre results in viable mice without differentiated cochlear hair cells that have lost most of the organ of Corti.
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Year: 2013
Journal: PLoS One
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First Author: Brophy PD
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Journal: Development
Title: Regulation of ureteric bud outgrowth by Pax2-dependent activation of the glial derived neurotrophic factor gene.
Volume: 128
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Journal: Genes Dev
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Title: Deterioration of the Medial Olivocochlear Efferent System Accelerates Age-Related Hearing Loss in Pax2-Isl1 Transgenic Mice.
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Title: Eya1 expression in the developing ear and kidney: towards the understanding of the pathogenesis of Branchio-Oto-Renal (BOR) syndrome.
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Title: Aphakia (ak), a mouse mutation affecting early eye development: fine mapping, consideration of candidate genes and altered Pax6 and Six3 gene expression pattern.
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Title: OTX1 compensates for OTX2 requirement in regionalisation of anterior neuroectoderm.
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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