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Search results 1 to 75 out of 75 for Phgdh

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Category: Publication
Type Details Score
Publication
First Author: Mattaini KR
Year: 2019
Journal: BMC Cancer
Title: Increased PHGDH expression promotes aberrant melanin accumulation.
Volume: 19
Issue: 1
Pages: 723
Publication
First Author: Vandekeere S
Year: 2018
Journal: Cell Metab
Title: Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells.
Volume: 28
Issue: 4
Pages: 573-587.e13
Publication
First Author: Okabe K
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Deletion of PHGDH in adipocytes improves glucose intolerance in diet-induced obese mice.
Volume: 504
Issue: 1
Pages: 309-314
Publication  
First Author: Sim WC
Year: 2020
Journal: Metabolism
Title: Downregulation of PHGDH expression and hepatic serine level contribute to the development of fatty liver disease.
Volume: 102
Pages: 154000
Publication  
First Author: D'Avola A
Year: 2022
Journal: J Clin Invest
Title: PHGDH is required for germinal center formation and is a therapeutic target in MYC-driven lymphoma.
Volume: 132
Issue: 9
Publication
First Author: Wilson JL
Year: 2020
Journal: Cell Rep
Title: Inverse Data-Driven Modeling and Multiomics Analysis Reveals Phgdh as a Metabolic Checkpoint of Macrophage Polarization and Proliferation.
Volume: 30
Issue: 5
Pages: 1542-1552.e7
Publication
First Author: Kawakami Y
Year: 2009
Journal: Neurosci Res
Title: Impaired neurogenesis in embryonic spinal cord of Phgdh knockout mice, a serine deficiency disorder model.
Volume: 63
Issue: 3
Pages: 184-93
Publication
First Author: Yang JH
Year: 2010
Journal: J Biol Chem
Title: Brain-specific Phgdh deletion reveals a pivotal role for L-serine biosynthesis in controlling the level of D-serine, an N-methyl-D-aspartate receptor co-agonist, in adult brain.
Volume: 285
Issue: 53
Pages: 41380-90
Publication
First Author: Sayano T
Year: 2013
Journal: FEBS J
Title: L-serine deficiency caused by genetic Phgdh deletion leads to robust induction of 4E-BP1 and subsequent repression of translation initiation in the developing central nervous system.
Volume: 280
Issue: 6
Pages: 1502-17
Publication
First Author: Zhang D
Year: 2023
Journal: Cell Metab
Title: PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy.
Volume: 35
Issue: 3
Pages: 517-534.e8
Publication
First Author: Sullivan MR
Year: 2019
Journal: Cell Metab
Title: Increased Serine Synthesis Provides an Advantage for Tumors Arising in Tissues Where Serine Levels Are Limiting.
Volume: 29
Issue: 6
Pages: 1410-1421.e4
Publication
First Author: Hayashi Y
Year: 2024
Journal: iScience
Title: Control of epigenomic landscape and development of fetal male germ cells through L-serine metabolism.
Volume: 27
Issue: 9
Pages: 110702
Publication
First Author: Yoshida K
Year: 2004
Journal: J Biol Chem
Title: Targeted disruption of the mouse 3-phosphoglycerate dehydrogenase gene causes severe neurodevelopmental defects and results in embryonic lethality.
Volume: 279
Issue: 5
Pages: 3573-7
Publication
First Author: Shen W
Year: 2021
Journal: Glia
Title: Effect of selectively knocking down key metabolic genes in Müller glia on photoreceptor health.
Volume: 69
Issue: 8
Pages: 1966-1986
Publication
First Author: Cho HM
Year: 2000
Journal: Gene
Title: Nucleotide sequence and differential expression of the human 3-phosphoglycerate dehydrogenase gene.
Volume: 245
Issue: 1
Pages: 193-201
Publication    
First Author: Miller IJ
Year: 1997
Journal: GenBank Submission
Title: Mus musculus A10 mRNA, partial cds
Pages: L21027
Publication
First Author: Furuya S
Year: 2008
Journal: Funct Integr Genomics
Title: Inactivation of the 3-phosphoglycerate dehydrogenase gene in mice: changes in gene expression and associated regulatory networks resulting from serine deficiency.
Volume: 8
Issue: 3
Pages: 235-49
Publication
First Author: Ehmsen JT
Year: 2013
Journal: J Neurosci
Title: D-serine in glia and neurons derives from 3-phosphoglycerate dehydrogenase.
Volume: 33
Issue: 30
Pages: 12464-9
Publication
First Author: Miller IJ
Year: 1993
Journal: Mol Cell Biol
Title: A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Krüppel family of nuclear proteins.
Volume: 13
Issue: 5
Pages: 2776-86
Publication
First Author: Le Douce J
Year: 2020
Journal: Cell Metab
Title: Impairment of Glycolysis-Derived l-Serine Production in Astrocytes Contributes to Cognitive Deficits in Alzheimer's Disease.
Volume: 31
Issue: 3
Pages: 503-517.e8
Publication
First Author: Silva-Álvarez C
Year: 2017
Journal: Mol Neurobiol
Title: Apical Polarization of SVCT2 in Apical Radial Glial Cells and Progenitors During Brain Development.
Volume: 54
Issue: 7
Pages: 5449-5467
Publication
First Author: Nilsson LM
Year: 2012
Journal: PLoS Genet
Title: Mouse genetics suggests cell-context dependency for Myc-regulated metabolic enzymes during tumorigenesis.
Volume: 8
Issue: 3
Pages: e1002573
Publication
First Author: Yamasaki M
Year: 2001
Journal: J Neurosci
Title: 3-Phosphoglycerate dehydrogenase, a key enzyme for l-serine biosynthesis, is preferentially expressed in the radial glia/astrocyte lineage and olfactory ensheathing glia in the mouse brain.
Volume: 21
Issue: 19
Pages: 7691-704
Publication
First Author: Mukhopadhyay P
Year: 2012
Journal: Birth Defects Res A Clin Mol Teratol
Title: Strain-specific modifier genes governing craniofacial phenotypes.
Volume: 94
Issue: 3
Pages: 162-75
Publication
First Author: Sakai K
Year: 2003
Journal: J Neurosci
Title: Neutral amino acid transporter ASCT1 is preferentially expressed in L-Ser-synthetic/storing glial cells in the mouse brain with transient expression in developing capillaries.
Volume: 23
Issue: 2
Pages: 550-60
Publication
First Author: Zhu S
Year: 2022
Journal: Circulation
Title: Mitochondrial Stress Induces an HRI-eIF2α Pathway Protective for Cardiomyopathy.
Volume: 146
Issue: 13
Pages: 1028-1031
Publication
First Author: Gao L
Year: 2015
Journal: J Clin Invest
Title: Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition.
Volume: 125
Issue: 7
Pages: 2808-24
Publication  
First Author: Huynh H
Year: 2023
Journal: J Mol Cell Cardiol
Title: DELE1 is protective for mitochondrial cardiomyopathy.
Volume: 175
Pages: 44-48
Publication
First Author: Luo XJ
Year: 2013
Journal: Hum Mol Genet
Title: GATA3 controls the specification of prosensory domain and neuronal survival in the mouse cochlea.
Volume: 22
Issue: 18
Pages: 3609-23
Publication
First Author: Radzishevsky I
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Impairment of serine transport across the blood-brain barrier by deletion of Slc38a5 causes developmental delay and motor dysfunction.
Volume: 120
Issue: 42
Pages: e2302780120
Publication  
First Author: Zhao K
Year: 2022
Journal: Development
Title: LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development.
Volume: 149
Issue: 6
Publication
First Author: Gineste C
Year: 2013
Journal: Neuromuscul Disord
Title: In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype.
Volume: 23
Issue: 4
Pages: 357-69
Publication
First Author: Werner HB
Year: 2007
Journal: J Neurosci
Title: Proteolipid protein is required for transport of sirtuin 2 into CNS myelin.
Volume: 27
Issue: 29
Pages: 7717-30
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication  
First Author: Li AM
Year: 2020
Journal: Cancer Lett
Title: The PHGDH enigma: Do cancer cells only need serine or also a redox modulator?
Volume: 476
Pages: 97-105
Publication
First Author: Jasani N
Year: 2025
Journal: Cancer Res
Title: PHGDH Induction by MAPK Is Essential for Melanoma Formation and Creates an Actionable Metabolic Vulnerability.
Volume: 85
Issue: 2
Pages: 314-328
Publication  
First Author: Yang S
Year: 2024
Journal: Brain Behav Immun
Title: Multi-omics analysis reveals GAPDH posttranscriptional regulation of IFN-γ and PHGDH as a metabolic checkpoint of microglia polarization.
Volume: 117
Pages: 155-166
Publication
First Author: Ma L
Year: 2013
Journal: Cell
Title: Control of nutrient stress-induced metabolic reprogramming by PKCζ in tumorigenesis.
Volume: 152
Issue: 3
Pages: 599-611
Publication
First Author: Shen L
Year: 2021
Journal: Cell Metab
Title: Serine metabolism antagonizes antiviral innate immunity by preventing ATP6V0d2-mediated YAP lysosomal degradation.
Volume: 33
Issue: 5
Pages: 971-987.e6
Publication
First Author: Neame S
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: The NMDA receptor activation by d-serine and glycine is controlled by an astrocytic Phgdh-dependent serine shuttle.
Volume: 116
Issue: 41
Pages: 20736-20742
Publication
First Author: Hamanaka RB
Year: 2018
Journal: Am J Respir Cell Mol Biol
Title: Inhibition of Phosphoglycerate Dehydrogenase Attenuates Bleomycin-induced Pulmonary Fibrosis.
Volume: 58
Issue: 5
Pages: 585-593
Publication
First Author: Tajan M
Year: 2021
Journal: Nat Commun
Title: Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy.
Volume: 12
Issue: 1
Pages: 366