|  Help  |  About  |  Contact Us

Search our database by keyword

- or -

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 70 out of 70 for Phlpp1

Category restricted to Publication (x)

0.026s

Categories

Category: Publication
« show all
Type Details Score
Publication
31408005 | J:278678
   
First Author: Cohen Katsenelson K
Year: 2019
Journal: Elife
Title: PHLPP1 counter-regulates STAT1-mediated inflammatory signaling.
Volume: 8
•
•
•
•
•
Publication
23072745 | J:225077
First Author: Chen B
Year: 2013
Journal: J Cereb Blood Flow Metab
Title: PHLPP1 gene deletion protects the brain from ischemic injury.
Volume: 33
Issue: 2
Pages: 196-204
•
•
•
•
•
Publication
20080691 | J:156530
First Author: Masubuchi S
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Protein phosphatase PHLPP1 controls the light-induced resetting of the circadian clock.
Volume: 107
Issue: 4
Pages: 1642-7
•
•
•
•
•
Publication
25411382 | J:230296
First Author: Moc C
Year: 2015
Journal: Cardiovasc Res
Title: Physiological activation of Akt by PHLPP1 deletion protects against pathological hypertrophy.
Volume: 105
Issue: 2
Pages: 160-70
•
•
•
•
•
Publication
31189651 | J:281076
First Author: Mattson AM
Year: 2019
Journal: J Biol Chem
Title: Deficiency in the phosphatase PHLPP1 suppresses osteoclast-mediated bone resorption and enhances bone formation in mice.
Volume: 294
Issue: 31
Pages: 11772-11784
•
•
•
•
•
Publication
34575866 | J:331252
 
First Author: Karkache IY
Year: 2021
Journal: Int J Mol Sci
Title: Myeloid Lineage Ablation of Phlpp1 Regulates M-CSF Signaling and Tempers Bone Resorption in Female Mice.
Volume: 22
Issue: 18
•
•
•
•
•
Publication
21840483 | J:176062
First Author: Chen M
Year: 2011
Journal: Cancer Cell
Title: Identification of PHLPP1 as a tumor suppressor reveals the role of feedback activation in PTEN-mutant prostate cancer progression.
Volume: 20
Issue: 2
Pages: 173-86
•
•
•
•
•
Publication
31582730 | J:293360
First Author: Zhang C
Year: 2019
Journal: Cell Death Dis
Title: Phlpp1 is associated with human intervertebral disc degeneration and its deficiency promotes healing after needle puncture injury in mice.
Volume: 10
Issue: 10
Pages: 754
•
•
•
•
•
Publication
34143773 | J:342570
First Author: Hanson MK
Year: 2021
Journal: PLoS One
Title: Phlpp1 is induced by estrogen in osteoclasts and its loss in Ctsk-expressing cells does not protect against ovariectomy-induced bone loss.
Volume: 16
Issue: 6
Pages: e0251732
•
•
•
•
•
Publication
27421891 | J:342572
First Author: Liu Y
Year: 2016
Journal: Learn Mem
Title: Deleting both PHLPP1 and CANP1 rescues impairments in long-term potentiation and learning in both single knockout mice.
Volume: 23
Issue: 8
Pages: 399-404
•
•
•
•
•
Publication
25827478 | J:287126
 
First Author: Jackson TC
Year: 2015
Journal: Sci Rep
Title: Detection of PHLPP1α/β in human and mouse brain by different anti-PHLPP1 antibodies.
Volume: 5
Pages: 9377
•
•
•
•
•
Publication
21986499 | J:178312
First Author: Liu J
Year: 2011
Journal: Mol Cell Biol
Title: PHLPP-mediated dephosphorylation of S6K1 inhibits protein translation and cell growth.
Volume: 31
Issue: 24
Pages: 4917-27
•
•
•
•
•
Publication
27320912 | J:238374
First Author: Wang Y
Year: 2016
Journal: Cell Rep
Title: Defects in the CAPN1 Gene Result in Alterations in Cerebellar Development and Cerebellar Ataxia in Mice and Humans.
Volume: 16
Issue: 1
Pages: 79-91
•
•
•
•
•
Publication
25953896 | J:223319
First Author: Bradley EW
Year: 2015
Journal: J Biol Chem
Title: Deletion of the PH-domain and Leucine-rich Repeat Protein Phosphatase 1 (Phlpp1) Increases Fibroblast Growth Factor (Fgf) 18 Expression and Promotes Chondrocyte Proliferation.
Volume: 290
Issue: 26
Pages: 16272-80
•
•
•
•
•
Publication
24703948 | J:213142
First Author: Wang P
Year: 2014
Journal: Mol Cell
Title: Both decreased and increased SRPK1 levels promote cancer by interfering with PHLPP-mediated dephosphorylation of Akt.
Volume: 54
Issue: 3
Pages: 378-91
•
•
•
•
•
Publication
21498666 | J:173220
First Author: Patterson SJ
Year: 2011
Journal: J Immunol
Title: Cutting edge: PHLPP regulates the development, function, and molecular signaling pathways of regulatory T cells.
Volume: 186
Issue: 10
Pages: 5533-7
•
•
•
•
•
Publication
26187040 | J:231241
First Author: Wen YA
Year: 2015
Journal: Biochim Biophys Acta
Title: Loss of PHLPP protects against colitis by inhibiting intestinal epithelial cell apoptosis.
Volume: 1852
Issue: 10 Pt A
Pages: 2013-23
•
•
•
•
•
Publication
33434347 | J:342571
First Author: Weaver SR
Year: 2021
Journal: J Bone Miner Res
Title: Pleckstrin homology (PH) domain and Leucine Rich Repeat Phosphatase 1 (Phlpp1) Suppresses Parathyroid Hormone Receptor 1 (Pth1r) Expression and Signaling During Bone Growth.
Volume: 36
Issue: 5
Pages: 986-999
•
•
•
•
•
Publication
27760826 | J:308383
First Author: Xiong X
Year: 2016
Journal: J Biol Chem
Title: Pleckstrin Homology (PH) Domain Leucine-rich Repeat Protein Phosphatase Controls Cell Polarity by Negatively Regulating the Activity of Atypical Protein Kinase C.
Volume: 291
Issue: 48
Pages: 25167-25178
•
•
•
•
•
Publication
23408427 | J:197836
First Author: Bradley EW
Year: 2013
Journal: J Biol Chem
Title: Histone deacetylase 3 suppression increases PH domain and leucine-rich repeat phosphatase (Phlpp)1 expression in chondrocytes to suppress Akt signaling and matrix secretion.
Volume: 288
Issue: 14
Pages: 9572-82
•
•
•
•
•
Publication
25820252 | J:227444
 
First Author: Fatima S
Year: 2015
Journal: Sci Rep
Title: Interactome of the negative regulator of nuclear import BRCA1-binding protein 2.
Volume: 5
Pages: 9459
•
•
•
•
•
Publication
24530606 | J:225239
First Author: Li X
Year: 2014
Journal: Gastroenterology
Title: PHLPP is a negative regulator of RAF1, which reduces colorectal cancer cell motility and prevents tumor progression in mice.
Volume: 146
Issue: 5
Pages: 1301-12.e1-10
•
•
•
•
•
Publication
17382888 | J:126510
First Author: Shimizu K
Year: 2007
Journal: Cell
Title: Proteolytic degradation of SCOP in the hippocampus contributes to activation of MAP kinase and memory.
Volume: 128
Issue: 6
Pages: 1219-29
•
•
•
•
•
Publication
31555304 | J:281789
 
First Author: Ran T
Year: 2019
Journal: Front Immunol
Title: Enhanced Neutrophil Immune Homeostasis Due to Deletion of PHLPP.
Volume: 10
Pages: 2127
•
•
•
•
•
Publication
29739983 | J:287125
First Author: Jackson TC
Year: 2018
Journal: Sci Rep
Title: Acute Physiology and Neurologic Outcomes after Brain Injury in SCOP/PHLPP1 KO Mice.
Volume: 8
Issue: 1
Pages: 7158
•
•
•
•
•
Publication
25201979 | J:216487
First Author: Reyes G
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Pleckstrin homology domain leucine-rich repeat protein phosphatases set the amplitude of receptor tyrosine kinase output.
Volume: 111
Issue: 38
Pages: E3957-65
•
•
•
•
•
Publication
34348155 | J:324786
First Author: Lupse B
Year: 2021
Journal: Cell Rep
Title: Inhibition of PHLPP1/2 phosphatases rescues pancreatic β-cells in diabetes.
Volume: 36
Issue: 5
Pages: 109490
•
•
•
•
•
Publication
27686624 | J:242361
 
First Author: Shimizu K
Year: 2016
Journal: Nat Commun
Title: SCOP/PHLPP1β mediates circadian regulation of long-term recognition memory.
Volume: 7
Pages: 12926
•
•
•
•
•
Publication
27640726 | J:250183
 
First Author: Nakano JJ
Year: 2016
Journal: Sci Rep
Title: SCOP/PHLPP1β in the basolateral amygdala regulates circadian expression of mouse anxiety-like behavior.
Volume: 6
Pages: 33500
•
•
•
•
•
Publication
20576936 | J:175033
First Author: Miyamoto S
Year: 2010
Journal: Circ Res
Title: PHLPP-1 negatively regulates Akt activity and survival in the heart.
Volume: 107
Issue: 4
Pages: 476-84
•
•
•
•
•
Publication
27721240 | J:239619
First Author: Rué L
Year: 2016
Journal: J Clin Invest
Title: Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels.
Volume: 126
Issue: 11
Pages: 4319-4330
•
•
•
•
•
Publication
22837474 | J:201479
First Author: Srivastava U
Year: 2012
Journal: Arterioscler Thromb Vasc Biol
Title: Differences in health status affect susceptibility and mapping of genetic loci for atherosclerosis (fatty streak) in inbred mice.
Volume: 32
Issue: 10
Pages: 2380-6
•
•
•
•
•
Publication
12465718 | J:86755
First Author: Okazaki N
Year: 2002
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 9
Issue: 5
Pages: 179-88
•
•
•
•
•
Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
•
•
•
•
•
Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
•
•
•
•
•
Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
•
•
•
•
•
Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
•
•
•
•
•
Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
•
•
•
•
•
Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
•
•
•
•
•
Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
•
•
•
•
•
Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
•
•
•
•
•
Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
•
•
•
•
•
Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
•
•
•
•
•
Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
•
•
•
•
•
Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
•
•
•
•
•
Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
•
•
•
•
•
Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
•
•
•
•
•
Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
•
•
•
•
•
Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
•
•
•
•
•
Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
•
•
•
•
•
Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
•
•
•
•
•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Publication
21701506 | J:200493
First Author: Li X
Year: 2011
Journal: EMBO Rep
Title: Scribble-mediated membrane targeting of PHLPP1 is required for its negative regulation of Akt.
Volume: 12
Issue: 8
Pages: 818-24
•
•
•
•
•
Publication
20574456 | J:164259
First Author: Hussain S
Year: 2010
Journal: Leukemia
Title: The de-ubiquitinase UCH-L1 is an oncogene that drives the development of lymphoma in vivo by deregulating PHLPP1 and Akt signaling.
Volume: 24
Issue: 9
Pages: 1641-55
•
•
•
•
•
Publication
23512990 | J:260390
First Author: Huang PH
Year: 2013
Journal: Sci Signal
Title: Vitamin E facilitates the inactivation of the kinase Akt by the phosphatase PHLPP1.
Volume: 6
Issue: 267
Pages: ra19
•
•
•
•
•
Publication
19745829 | J:169436
First Author: Saavedra A
Year: 2010
Journal: Cell Death Differ
Title: PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum.
Volume: 17
Issue: 2
Pages: 324-35
•
•
•
•
•
Publication
24285894 | J:352203
First Author: Wang Y
Year: 2013
Journal: J Neurosci
Title: Distinct roles for μ-calpain and m-calpain in synaptic NMDAR-mediated neuroprotection and extrasynaptic NMDAR-mediated neurodegeneration.
Volume: 33
Issue: 48
Pages: 18880-92
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom