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Search results 1 to 100 out of 560 for Prf1

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Category: Publication
Type Details Score
Publication
First Author: Fink TM
Year: 1992
Journal: Genomics
Title: Human perforin (PRF1) maps to 10q22, a region that is syntenic with mouse chromosome 10.
Volume: 13
Issue: 4
Pages: 1300-2
Publication
First Author: Albeituni S
Year: 2019
Journal: Blood
Title: Mechanisms of action of ruxolitinib in murine models of hemophagocytic lymphohistiocytosis.
Volume: 134
Issue: 2
Pages: 147-159
Publication
First Author: van Dommelen SL
Year: 2006
Journal: Immunity
Title: Perforin and granzymes have distinct roles in defensive immunity and immunopathology.
Volume: 25
Issue: 5
Pages: 835-48
Publication
First Author: Lee SH
Year: 2009
Journal: J Exp Med
Title: Activating receptors promote NK cell expansion for maintenance, IL-10 production, and CD8 T cell regulation during viral infection.
Volume: 206
Issue: 10
Pages: 2235-51
Publication
First Author: Pearson T
Year: 2008
Journal: Diabetologia
Title: A new immunodeficient hyperglycaemic mouse model based on the Ins2Akita mutation for analyses of human islet and beta stem and progenitor cell function.
Volume: 51
Issue: 8
Pages: 1449-56
Publication
First Author: Kwon BS
Year: 1989
Journal: Biochem Biophys Res Commun
Title: The structure of the mouse lymphocyte pore-forming protein perforin.
Volume: 158
Issue: 1
Pages: 1-10
Publication
First Author: Shinkai Y
Year: 1988
Journal: Nature
Title: Homology of perforin to the ninth component of complement (C9).
Volume: 334
Issue: 6182
Pages: 525-7
Publication
First Author: Lowrey DM
Year: 1989
Journal: Proc Natl Acad Sci U S A
Title: Cloning, analysis, and expression of murine perforin 1 cDNA, a component of cytolytic T-cell granules with homology to complement component C9.
Volume: 86
Issue: 1
Pages: 247-51
Publication
First Author: Lichtenheld MG
Year: 1992
Journal: J Immunol
Title: Structure and function of the murine perforin promoter and upstream region. Reciprocal gene activation or silencing in perforin positive and negative cells.
Volume: 149
Issue: 8
Pages: 2619-26
Publication
First Author: Kägi D
Year: 1994
Journal: Nature
Title: Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice.
Volume: 369
Issue: 6475
Pages: 31-7
Publication
First Author: Walsh CM
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Immune function in mice lacking the perforin gene.
Volume: 91
Issue: 23
Pages: 10854-8
Publication
First Author: Law RH
Year: 2010
Journal: Nature
Title: The structural basis for membrane binding and pore formation by lymphocyte perforin.
Volume: 468
Issue: 7322
Pages: 447-51
Publication
First Author: Choy JC
Year: 2004
Journal: Am J Pathol
Title: Perforin mediates endothelial cell death and resultant transplant vascular disease in cardiac allografts.
Volume: 165
Issue: 1
Pages: 127-33
Publication
First Author: Seki N
Year: 2002
Journal: J Immunol
Title: Tumor-specific CTL kill murine renal cancer cells using both perforin and Fas ligand-mediated lysis in vitro, but cause tumor regression in vivo in the absence of perforin.
Volume: 168
Issue: 7
Pages: 3484-92
Publication
First Author: Zlotnikov-Klionsky Y
Year: 2015
Journal: Immunity
Title: Perforin-Positive Dendritic Cells Exhibit an Immuno-regulatory Role in Metabolic Syndrome and Autoimmunity.
Volume: 43
Issue: 4
Pages: 776-87
Publication
First Author: Kuhla A
Year: 2009
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Role of the perforin/granzyme cell death pathway in D-Gal/LPS-induced inflammatory liver injury.
Volume: 296
Issue: 5
Pages: G1069-76
Publication
First Author: Suidan GL
Year: 2010
Journal: J Immunol
Title: CD8 T cell-initiated vascular endothelial growth factor expression promotes central nervous system vascular permeability under neuroinflammatory conditions.
Volume: 184
Issue: 2
Pages: 1031-40
Publication
First Author: Schulz M
Year: 1995
Journal: Eur J Immunol
Title: Acute rejection of vascular heart allografts by perforin-deficient mice.
Volume: 25
Issue: 2
Pages: 474-80
Publication
First Author: Jensen S
Year: 2013
Journal: J Immunol
Title: Adenovirus-based vaccine against Listeria monocytogenes: extending the concept of invariant chain linkage.
Volume: 191
Issue: 8
Pages: 4152-64
Publication
First Author: Frese-Schaper M
Year: 2014
Journal: Cancer Immunol Immunother
Title: Influence of natural killer cells and perforin‑mediated cytolysis on the development of chemically induced lung cancer in A/J mice.
Volume: 63
Issue: 6
Pages: 571-80
Publication
First Author: Holst PJ
Year: 2011
Journal: J Immunol
Title: Vaccination against lymphocytic choriomeningitis virus infection in MHC class II-deficient mice.
Volume: 186
Issue: 7
Pages: 3997-4007
Publication
First Author: Dyer CM
Year: 2004
Journal: Blood
Title: Unexpectedly, induction of cytotoxic T lymphocytes enhances the humoral response after DNA immunization.
Volume: 103
Issue: 8
Pages: 3073-5
Publication
First Author: Sagiv A
Year: 2013
Journal: Oncogene
Title: Granule exocytosis mediates immune surveillance of senescent cells.
Volume: 32
Issue: 15
Pages: 1971-7
Publication
First Author: Johnson HL
Year: 2014
Journal: PLoS One
Title: Perforin competent CD8 T cells are sufficient to cause immune-mediated blood-brain barrier disruption.
Volume: 9
Issue: 10
Pages: e111401
Publication
First Author: Garofalo S
Year: 2020
Journal: Nat Commun
Title: Natural killer cells modulate motor neuron-immune cell cross talk in models of Amyotrophic Lateral Sclerosis.
Volume: 11
Issue: 1
Pages: 1773
Publication
First Author: Spaner D
Year: 1999
Journal: J Immunol
Title: A role for perforin in activation-induced T cell death in vivo: increased expansion of allogeneic perforin-deficient T cells in SCID mice.
Volume: 162
Issue: 2
Pages: 1192-9
Publication
First Author: Epardaud M
Year: 2008
Journal: Cancer Res
Title: Interleukin-15/interleukin-15R alpha complexes promote destruction of established tumors by reviving tumor-resident CD8+ T cells.
Volume: 68
Issue: 8
Pages: 2972-83
Publication
First Author: Kägi D
Year: 1997
Journal: J Exp Med
Title: Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice.
Volume: 186
Issue: 7
Pages: 989-97
Publication
First Author: Zhou P
Year: 2001
Journal: J Immunol
Title: Perforin is required for primary immunity to Histoplasma capsulatum.
Volume: 166
Issue: 3
Pages: 1968-74
Publication
First Author: Dotiwala F
Year: 2016
Journal: Nat Med
Title: Killer lymphocytes use granulysin, perforin and granzymes to kill intracellular parasites.
Volume: 22
Issue: 2
Pages: 210-6
Publication
First Author: Das R
Year: 2016
Journal: Blood
Title: Janus kinase inhibition lessens inflammation and ameliorates disease in murine models of hemophagocytic lymphohistiocytosis.
Volume: 127
Issue: 13
Pages: 1666-75
Publication
First Author: Street SE
Year: 2007
Journal: Cancer Res
Title: Host perforin reduces tumor number but does not increase survival in oncogene-driven mammary adenocarcinoma.
Volume: 67
Issue: 11
Pages: 5454-60
Publication
First Author: Doloff JC
Year: 2012
Journal: Cancer Res
Title: VEGF receptor inhibitors block the ability of metronomically dosed cyclophosphamide to activate innate immunity-induced tumor regression.
Volume: 72
Issue: 5
Pages: 1103-15
Publication
First Author: Ciurea A
Year: 2001
Journal: Nat Med
Title: CD4+ T-cell-epitope escape mutant virus selected in vivo.
Volume: 7
Issue: 7
Pages: 795-800
Publication
First Author: Sarcon AK
Year: 2009
Journal: Exp Hematol
Title: Role of perforin-mediated cell apoptosis in murine models of infusion-induced bone marrow failure.
Volume: 37
Issue: 4
Pages: 477-86
Publication    
First Author: Gutwillig A
Year: 2022
Journal: Elife
Title: Transient cell-in-cell formation underlies tumor relapse and resistance to immunotherapy.
Volume: 11
Publication
First Author: Meyer LK
Year: 2020
Journal: Blood
Title: JAK/STAT pathway inhibition sensitizes CD8 T cells to dexamethasone-induced apoptosis in hyperinflammation.
Volume: 136
Issue: 6
Pages: 657-668
Publication
First Author: Freeman AJ
Year: 2019
Journal: Cell Rep
Title: Natural Killer Cells Suppress T Cell-Associated Tumor Immune Evasion.
Volume: 28
Issue: 11
Pages: 2784-2794.e5
Publication  
First Author: Cuff AO
Year: 2019
Journal: Front Immunol
Title: The Obese Liver Environment Mediates Conversion of NK Cells to a Less Cytotoxic ILC1-Like Phenotype.
Volume: 10
Pages: 2180
Publication
First Author: Johnson RM
Year: 2013
Journal: PLoS One
Title: Perforin is detrimental to controlling [corrected] C. muridarum replication in vitro, but not in vivo.
Volume: 8
Issue: 5
Pages: e63340
Publication  
First Author: Pan Y
Year: 2021
Journal: Front Cell Neurosci
Title: Inhibition of Perforin-Mediated Neurotoxicity Attenuates Neurological Deficits After Ischemic Stroke.
Volume: 15
Pages: 664312
Publication
First Author: Keenan C
Year: 2024
Journal: Blood
Title: Differential effects of itacitinib, fedratinib, and ruxolitinib in mouse models of hemophagocytic lymphohistiocytosis.
Volume: 143
Issue: 23
Pages: 2386-2400
Publication
First Author: Cretney E
Year: 1999
Journal: J Exp Med
Title: m144, a murine cytomegalovirus (MCMV)-encoded major histocompatibility complex class I homologue, confers tumor resistance to natural killer cell-mediated rejection.
Volume: 190
Issue: 3
Pages: 435-44
Publication
First Author: Enomoto N
Year: 2012
Journal: J Immunol
Title: Allergen-specific CTL require perforin expression to suppress allergic airway inflammation.
Volume: 188
Issue: 4
Pages: 1734-41
Publication
First Author: Zhang T
Year: 2012
Journal: J Immunol
Title: An NKp30-based chimeric antigen receptor promotes T cell effector functions and antitumor efficacy in vivo.
Volume: 189
Issue: 5
Pages: 2290-9
Publication
First Author: Liu B
Year: 2003
Journal: Microb Pathog
Title: Local immune responses to influenza virus infection in mice with a targeted disruption of perforin gene.
Volume: 34
Issue: 4
Pages: 161-7
Publication
First Author: Ip CW
Year: 2012
Journal: PLoS One
Title: Neuroinflammation by cytotoxic T-lymphocytes impairs retrograde axonal transport in an oligodendrocyte mutant mouse.
Volume: 7
Issue: 8
Pages: e42554
Publication
First Author: Palma JP
Year: 2001
Journal: J Neuroimmunol
Title: Enhanced susceptibility to Theiler's virus-induced demyelinating disease in perforin-deficient mice.
Volume: 116
Issue: 2
Pages: 125-35
Publication
First Author: Terrell CE
Year: 2013
Journal: Blood
Title: Perforin deficiency impairs a critical immunoregulatory loop involving murine CD8(+) T cells and dendritic cells.
Volume: 121
Issue: 26
Pages: 5184-91
Publication
First Author: Olson JA
Year: 2013
Journal: Immunity
Title: Effector-like CD8⁺ T cells in the memory population mediate potent protective immunity.
Volume: 38
Issue: 6
Pages: 1250-60
Publication
First Author: Yang J
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Perforin-dependent elimination of dendritic cells regulates the expansion of antigen-specific CD8+ T cells in vivo.
Volume: 103
Issue: 1
Pages: 147-52
Publication
First Author: Johnson TS
Year: 2014
Journal: J Immunol
Title: Etoposide selectively ablates activated T cells to control the immunoregulatory disorder hemophagocytic lymphohistiocytosis.
Volume: 192
Issue: 1
Pages: 84-91
Publication
First Author: Schulert GS
Year: 2018
Journal: Int Immunol
Title: Convergent pathways of the hyperferritinemic syndromes.
Volume: 30
Issue: 5
Pages: 195-203
Publication
First Author: Henriques-Pons A
Year: 2002
Journal: Int J Exp Pathol
Title: Evidence for a perforin-mediated mechanism controlling cardiac inflammation in Trypanosoma cruzi infection.
Volume: 83
Issue: 2
Pages: 67-79
Publication
First Author: Tiwari A
Year: 2019
Journal: Am J Pathol
Title: Penetration of CD8+ Cytotoxic T Cells into Large Target, Tissue Cysts of Toxoplasma gondii, Leads to Its Elimination.
Volume: 189
Issue: 8
Pages: 1594-1607
Publication
First Author: White DW
Year: 1999
Journal: J Immunol
Title: Perforin-deficient CD8+ T cells: in vivo priming and antigen-specific immunity against Listeria monocytogenes.
Volume: 162
Issue: 2
Pages: 980-8
Publication
First Author: Bouwer AL
Year: 2014
Journal: J Immunol
Title: NK cells are required for dendritic cell-based immunotherapy at the time of tumor challenge.
Volume: 192
Issue: 5
Pages: 2514-21
Publication
First Author: Peng SP
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Participation of perforin in mediating dopaminergic neuron loss in MPTP-induced Parkinson's disease in mice.
Volume: 484
Issue: 3
Pages: 618-622
Publication
First Author: Felzen B
Year: 1998
Journal: Circ Res
Title: Fas (CD95/Apo-1)-mediated damage to ventricular myocytes induced by cytotoxic T lymphocytes from perforin-deficient mice: a major role for inositol 1,4,5-trisphosphate.
Volume: 82
Issue: 4
Pages: 438-50
Publication
First Author: Liu K
Year: 2005
Journal: Cancer Res
Title: Immune selection and emergence of aggressive tumor variants as negative consequences of Fas-mediated cytotoxicity and altered IFN-gamma-regulated gene expression.
Volume: 65
Issue: 10
Pages: 4376-88
Publication
First Author: Gebhard JR
Year: 1998
Journal: Am J Pathol
Title: Coxsackievirus B3-induced myocarditis: perforin exacerbates disease, but plays no detectable role in virus clearance.
Volume: 153
Issue: 2
Pages: 417-28
Publication
First Author: Messingham KA
Year: 2003
Journal: J Immunol
Title: Deficient anti-listerial immunity in the absence of perforin can be restored by increasing memory CD8+ T cell numbers.
Volume: 171
Issue: 8
Pages: 4254-62
Publication
First Author: Silverio JC
Year: 2010
Journal: Int J Exp Pathol
Title: Perforin-expressing cytotoxic cells contribute to chronic cardiomyopathy in Trypanosoma cruzi infection.
Volume: 91
Issue: 1
Pages: 72-86
Publication
First Author: Liu CC
Year: 1995
Journal: J Immunol
Title: Morphologic and functional characterization of perforin-deficient lymphokine-activated killer cells.
Volume: 155
Issue: 2
Pages: 602-8
Publication
First Author: Pham NL
Year: 2012
Journal: Eur J Immunol
Title: Epitope specificity of memory CD8+ T cells dictates vaccination-induced mortality in LCMV-infected perforin-deficient mice.
Volume: 42
Issue: 6
Pages: 1488-99
Publication
First Author: Sambhara S
Year: 1998
Journal: Cell Immunol
Title: Enhanced antibody and cytokine responses to influenza viral antigens in perforin-deficient mice.
Volume: 187
Issue: 1
Pages: 13-8
Publication
First Author: Aung S
Year: 2001
Journal: J Virol
Title: Alternative mechanisms of respiratory syncytial virus clearance in perforin knockout mice lead to enhanced disease.
Volume: 75
Issue: 20
Pages: 9918-24
Publication
First Author: Badovinac VP
Year: 2003
Journal: Immunity
Title: Viral infection results in massive CD8+ T cell expansion and mortality in vaccinated perforin-deficient mice.
Volume: 18
Issue: 4
Pages: 463-74
Publication
First Author: Brown DM
Year: 2009
Journal: Cell Immunol
Title: IL-2 and antigen dose differentially regulate perforin- and FasL-mediated cytolytic activity in antigen specific CD4+ T cells.
Volume: 257
Issue: 1-2
Pages: 69-79
Publication
First Author: Schmidt ME
Year: 2018
Journal: PLoS Pathog
Title: Memory CD8 T cells mediate severe immunopathology following respiratory syncytial virus infection.
Volume: 14
Issue: 1
Pages: e1006810
Publication
First Author: White DW
Year: 1998
Journal: J Immunol
Title: Perforin-deficient CD8+ T cells provide immunity to Listeria monocytogenes by a mechanism that is independent of CD95 and IFN-gamma but requires TNF-alpha.
Volume: 160
Issue: 2
Pages: 898-905
Publication
First Author: Lowin B
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: A null mutation in the perforin gene impairs cytolytic T lymphocyte- and natural killer cell-mediated cytotoxicity.
Volume: 91
Issue: 24
Pages: 11571-5
Publication
First Author: Joshi PS
Year: 2006
Journal: J Leukoc Biol
Title: Cytokine-induced killer T cells kill immature dendritic cells by TCR-independent and perforin-dependent mechanisms.
Volume: 80
Issue: 6
Pages: 1345-53
Publication      
First Author: Zhang D
Year: 2014
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for prime. Updated on December 15, 2014.
Publication
First Author: Yagi H
Year: 2015
Journal: J Biol Chem
Title: Structural Basis for Ca2+-mediated Interaction of the Perforin C2 Domain with Lipid Membranes.
Volume: 290
Issue: 42
Pages: 25213-26
Publication
First Author: Ivanova ME
Year: 2022
Journal: Sci Adv
Title: The pore conformation of lymphocyte perforin.
Volume: 8
Issue: 6
Pages: eabk3147
Publication
First Author: Tvinnereim AR
Year: 2002
Journal: Infect Immun
Title: CD8(+)-T-cell response to secreted and nonsecreted antigens delivered by recombinant Listeria monocytogenes during secondary infection.
Volume: 70
Issue: 1
Pages: 153-62
Publication
First Author: Austin Taylor M
Year: 2000
Journal: J Immunol
Title: Functional defects of NK cells treated with chloroquine mimic the lytic defects observed in perforin-deficient mice.
Volume: 165
Issue: 9
Pages: 5048-53
Publication
First Author: Trapani JA
Year: 1990
Journal: Tissue Antigens
Title: Novel putative promoter/enhancer sequences are shared by the mouse and human perforin (Pfp) genes.
Volume: 36
Issue: 5
Pages: 228-34
Publication
First Author: Kawasaki A
Year: 1992
Journal: Eur J Immunol
Title: Expression of perforin in murine natural killer cells and cytotoxic T lymphocytes in vivo.
Volume: 22
Issue: 5
Pages: 1215-9
Publication
First Author: García-Sanz JA
Year: 1993
Journal: Eur J Immunol
Title: Regulation of perforin gene expression in a T cell hybrid with inducible cytolytic activity.
Volume: 23
Issue: 8
Pages: 1877-83
Publication
First Author: Zheng LM
Year: 1993
Journal: Eur J Immunol
Title: Distribution of perforin-containing cells in normal and pregnant mice.
Volume: 23
Issue: 9
Pages: 2085-91
Publication
First Author: Liu CC
Year: 1995
Journal: Immunol Today
Title: Perforin: structure and function.
Volume: 16
Issue: 4
Pages: 194-201
Publication
First Author: Spaner D
Year: 1998
Journal: J Immunol
Title: A role for perforin in activation-induced cell death.
Volume: 160
Issue: 6
Pages: 2655-64
Publication
First Author: Zhang D
Year: 2007
Journal: Blood
Title: New differentiation pathway for double-negative regulatory T cells that regulates the magnitude of immune responses.
Volume: 109
Issue: 9
Pages: 4071-9
Publication
First Author: Voskoboinik I
Year: 2007
Journal: Blood
Title: Perforin activity and immune homeostasis: the common A91V polymorphism in perforin results in both presynaptic and postsynaptic defects in function.
Volume: 110
Issue: 4
Pages: 1184-90
Publication
First Author: Persson CM
Year: 2009
Journal: Infect Immun
Title: Transmission of Toxoplasma gondii from infected dendritic cells to natural killer cells.
Volume: 77
Issue: 3
Pages: 970-6
Publication
First Author: Brennan AJ
Year: 2011
Journal: Immunity
Title: Protection from endogenous perforin: glycans and the C terminus regulate exocytic trafficking in cytotoxic lymphocytes.
Volume: 34
Issue: 6
Pages: 879-92
Publication
First Author: Terrell CE
Year: 2013
Journal: Blood
Title: Mixed hematopoietic or T-cell chimerism above a minimal threshold restores perforin-dependent immune regulation in perforin-deficient mice.
Volume: 122
Issue: 15
Pages: 2618-21
Publication
First Author: Traore DA
Year: 2013
Journal: Biochem J
Title: Defining the interaction of perforin with calcium and the phospholipid membrane.
Volume: 456
Issue: 3
Pages: 323-35
Publication
First Author: Macagno M
Year: 2014
Journal: J Immunol
Title: Multiple roles of perforin in hampering ERBB-2 (Her-2/neu) carcinogenesis in transgenic male mice.
Volume: 192
Issue: 11
Pages: 5434-41
Publication  
First Author: Huggins MA
Year: 2017
Journal: Infect Immun
Title: Perforin Expression by CD8 T Cells Is Sufficient To Cause Fatal Brain Edema during Experimental Cerebral Malaria.
Volume: 85
Issue: 5
Publication
First Author: Zhang Z
Year: 2020
Journal: Nature
Title: Gasdermin E suppresses tumour growth by activating anti-tumour immunity.
Volume: 579
Issue: 7799
Pages: 415-420
Publication
First Author: Lacorazza HD
Year: 2002
Journal: Immunity
Title: The ETS protein MEF plays a critical role in perforin gene expression and the development of natural killer and NK-T cells.
Volume: 17
Issue: 4
Pages: 437-49
Publication
First Author: Alves BN
Year: 2009
Journal: J Leukoc Biol
Title: Pancreatic lipase-related protein 2 (PLRP2) induction by IL-4 in cytotoxic T lymphocytes (CTLs) and reevaluation of the negative effects of its gene ablation on cytotoxicity.
Volume: 86
Issue: 3
Pages: 701-12
Publication
First Author: Jessen B
Year: 2011
Journal: Blood
Title: Subtle differences in CTL cytotoxicity determine susceptibility to hemophagocytic lymphohistiocytosis in mice and humans with Chediak-Higashi syndrome.
Volume: 118
Issue: 17
Pages: 4620-9
Publication
First Author: Pachlopnik Schmid J
Year: 2008
Journal: Eur J Immunol
Title: A Griscelli syndrome type 2 murine model of hemophagocytic lymphohistiocytosis (HLH).
Volume: 38
Issue: 11
Pages: 3219-25
Publication
First Author: Pachlopnik Schmid J
Year: 2009
Journal: EMBO Mol Med
Title: Neutralization of IFNgamma defeats haemophagocytosis in LCMV-infected perforin- and Rab27a-deficient mice.
Volume: 1
Issue: 2
Pages: 112-24
Publication
First Author: Revelo XS
Year: 2015
Journal: Diabetes
Title: Perforin is a novel immune regulator of obesity-related insulin resistance.
Volume: 64
Issue: 1
Pages: 90-103
Publication
First Author: Duthie MS
Year: 2006
Journal: Immunology
Title: During acute Trypanosoma cruzi infection highly susceptible mice deficient in natural killer cells are protected by a single alpha-galactosylceramide treatment.
Volume: 119
Issue: 3
Pages: 355-61