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Search results 1 to 100 out of 1736 for Rag2

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Category: Publication
Type Details Score
Publication
First Author: Fugmann SD
Year: 2002
Journal: Nature
Title: DNA repair: breaking the seal.
Volume: 416
Issue: 6882
Pages: 691-4
Publication
First Author: Yu W
Year: 1999
Journal: Science
Title: Coordinate regulation of RAG1 and RAG2 by cell type-specific DNA elements 5' of RAG2.
Volume: 285
Issue: 5430
Pages: 1080-4
Publication
First Author: Deriano L
Year: 2011
Journal: Nature
Title: The RAG2 C terminus suppresses genomic instability and lymphomagenesis.
Volume: 471
Issue: 7336
Pages: 119-23
Publication
First Author: Akamatsu Y
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Deletion of the RAG2 C terminus leads to impaired lymphoid development in mice.
Volume: 100
Issue: 3
Pages: 1209-14
Publication
First Author: Marrella V
Year: 2007
Journal: J Clin Invest
Title: A hypomorphic R229Q Rag2 mouse mutant recapitulates human Omenn syndrome.
Volume: 117
Issue: 5
Pages: 1260-9
Publication
First Author: Laszkiewicz A
Year: 2011
Journal: Immunogenetics
Title: Complexity of transcriptional regulation within the Rag locus: identification of a second Nwc promoter region within the Rag2 intron.
Volume: 63
Issue: 3
Pages: 183-7
Publication
First Author: Han S
Year: 1996
Journal: Science
Title: Neoteny in lymphocytes: Rag1 and Rag2 expression in germinal center B cells.
Volume: 274
Issue: 5295
Pages: 2094-7
Publication
First Author: Matthews AG
Year: 2007
Journal: Nature
Title: RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination.
Volume: 450
Issue: 7172
Pages: 1106-10
Publication
First Author: Jin Y
Year: 2019
Journal: Sci Rep
Title: The R229Q mutation of Rag2 does not characterize severe immunodeficiency in mice.
Volume: 9
Issue: 1
Pages: 4415
Publication
First Author: Shetty K
Year: 2015
Journal: Mol Cell Biol
Title: Recruitment of RAG1 and RAG2 to Chromatinized DNA during V(D)J Recombination.
Volume: 35
Issue: 21
Pages: 3701-13
Publication
First Author: Hao B
Year: 2015
Journal: J Exp Med
Title: An anti-silencer- and SATB1-dependent chromatin hub regulates Rag1 and Rag2 gene expression during thymocyte development.
Volume: 212
Issue: 5
Pages: 809-24
Publication
First Author: Monroe RJ
Year: 1999
Journal: Immunity
Title: RAG2:GFP knockin mice reveal novel aspects of RAG2 expression in primary and peripheral lymphoid tissues.
Volume: 11
Issue: 2
Pages: 201-12
Publication
First Author: Ji Y
Year: 2010
Journal: Cell
Title: The in vivo pattern of binding of RAG1 and RAG2 to antigen receptor loci.
Volume: 141
Issue: 3
Pages: 419-31
Publication
First Author: Ramón-Maiques S
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2.
Volume: 104
Issue: 48
Pages: 18993-8
Publication
First Author: Elkin SK
Year: 2005
Journal: J Biol Chem
Title: A PHD finger motif in the C terminus of RAG2 modulates recombination activity.
Volume: 280
Issue: 31
Pages: 28701-10
Publication
First Author: Roh YJ
Year: 2023
Journal: Lab Anim Res
Title: Comparison of immunophenotypes between Rag2 knockout mice derived from two different sources.
Volume: 39
Issue: 1
Pages: 2
Publication
First Author: Xu K
Year: 2016
Journal: Eur J Immunol
Title: Disruption of the RAG2 zinc finger motif impairs protein stability and causes immunodeficiency.
Volume: 46
Issue: 4
Pages: 1011-9
Publication  
First Author: Lescale C
Year: 2016
Journal: Nat Commun
Title: RAG2 and XLF/Cernunnos interplay reveals a novel role for the RAG complex in DNA repair.
Volume: 7
Pages: 10529
Publication
First Author: Goldman JP
Year: 1998
Journal: Br J Haematol
Title: Enhanced human cell engraftment in mice deficient in RAG2 and the common cytokine receptor gamma chain.
Volume: 103
Issue: 2
Pages: 335-42
Publication
First Author: Grawunder U
Year: 1995
Journal: Immunity
Title: Down-regulation of RAG1 and RAG2 gene expression in preB cells after functional immunoglobulin heavy chain rearrangement.
Volume: 3
Issue: 5
Pages: 601-8
Publication
First Author: Golumbek PT
Year: 2007
Journal: Neuromuscul Disord
Title: Strength and corticosteroid responsiveness of mdx mice is unchanged by RAG2 gene knockout.
Volume: 17
Issue: 5
Pages: 376-84
Publication
First Author: Liang HE
Year: 2002
Journal: Immunity
Title: The "dispensable" portion of RAG2 is necessary for efficient V-to-DJ rearrangement during B and T cell development.
Volume: 17
Issue: 5
Pages: 639-51
Publication
First Author: Barreto V
Year: 2001
Journal: Eur J Immunol
Title: Early death and severe lymphopenia caused by ubiquitous expression of the Rag1 and Rag2 genes in mice.
Volume: 31
Issue: 12
Pages: 3763-72
Publication
First Author: Maina V
Year: 2013
Journal: J Leukoc Biol
Title: Hypomorphic mutation in the RAG2 gene affects dendritic cell distribution and migration.
Volume: 94
Issue: 6
Pages: 1221-30
Publication
First Author: Cassani B
Year: 2010
Journal: J Exp Med
Title: Homeostatic expansion of autoreactive immunoglobulin-secreting cells in the Rag2 mouse model of Omenn syndrome.
Volume: 207
Issue: 7
Pages: 1525-40
Publication
First Author: Sugimoto E
Year: 2023
Journal: Commun Biol
Title: Hyperactive Natural Killer cells in Rag2 knockout mice inhibit the development of acute myeloid leukemia.
Volume: 6
Issue: 1
Pages: 1294
Publication
First Author: Grundy GJ
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Autoinhibition of DNA cleavage mediated by RAG1 and RAG2 is overcome by an epigenetic signal in V(D)J recombination.
Volume: 107
Issue: 52
Pages: 22487-92
Publication
First Author: Couëdel C
Year: 2010
Journal: J Clin Invest
Title: Analysis of mutations from SCID and Omenn syndrome patients reveals the central role of the Rag2 PHD domain in regulating V(D)J recombination.
Volume: 120
Issue: 4
Pages: 1337-44
Publication
First Author: Hsu LY
Year: 2003
Journal: Immunity
Title: A conserved transcriptional enhancer regulates RAG gene expression in developing B cells.
Volume: 19
Issue: 1
Pages: 105-17
Publication  
First Author: Clark SM
Year: 2015
Journal: Behav Brain Res
Title: Dissociation between sickness behavior and emotionality during lipopolysaccharide challenge in lymphocyte deficient Rag2(-/-) mice.
Volume: 278
Pages: 74-82
Publication
First Author: Amin RH
Year: 2008
Journal: Nat Immunol
Title: Foxo1 directly regulates the transcription of recombination-activating genes during B cell development.
Volume: 9
Issue: 6
Pages: 613-22
Publication
First Author: Borghesi L
Year: 2004
Journal: J Exp Med
Title: B lineage-specific regulation of V(D)J recombinase activity is established in common lymphoid progenitors.
Volume: 199
Issue: 4
Pages: 491-502
Publication
First Author: Johnson K
Year: 2012
Journal: J Immunol
Title: IL-7 functionally segregates the pro-B cell stage by regulating transcription of recombination mediators across cell cycle.
Volume: 188
Issue: 12
Pages: 6084-92
Publication
First Author: Yannoutsos N
Year: 2004
Journal: Nat Immunol
Title: A cis element in the recombination activating gene locus regulates gene expression by counteracting a distant silencer.
Volume: 5
Issue: 4
Pages: 443-50
Publication
First Author: McCaughtry TM
Year: 2007
Journal: J Exp Med
Title: Thymic emigration revisited.
Volume: 204
Issue: 11
Pages: 2513-20
Publication
First Author: Yu W
Year: 1999
Journal: Nature
Title: Continued RAG expression in late stages of B cell development and no apparent re-induction after immunization.
Volume: 400
Issue: 6745
Pages: 682-7
Publication
First Author: Oettinger MA
Year: 1992
Journal: Trends Genet
Title: Activation of V(D)J recombination by RAG1 and RAG2.
Volume: 8
Issue: 12
Pages: 413-6
Publication
First Author: Borghesi L
Year: 2005
Journal: J Exp Med
Title: E47 is required for V(D)J recombinase activity in common lymphoid progenitors.
Volume: 202
Issue: 12
Pages: 1669-77
Publication
First Author: Son YM
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Modulation of RAG/DNA complex by HSP70 in V(D)J recombination.
Volume: 365
Issue: 1
Pages: 113-7
Publication  
First Author: Ogawa Y
Year: 2016
Journal: Elife
Title: MHC-compatible bone marrow stromal/stem cells trigger fibrosis by activating host T cells in a scleroderma mouse model.
Volume: 5
Pages: e09394
Publication
First Author: Hansen JD
Year: 1996
Journal: Immunogenetics
Title: The recombination activating gene 2 (RAG2) of the rainbow trout Oncorhynchus mykiss.
Volume: 44
Issue: 3
Pages: 203-11
Publication
First Author: Yin FF
Year: 2009
Journal: Nat Struct Mol Biol
Title: Structure of the RAG1 nonamer binding domain with DNA reveals a dimer that mediates DNA synapsis.
Volume: 16
Issue: 5
Pages: 499-508
Publication
First Author: Shreedhar V
Year: 1999
Journal: Immunity
Title: Dendritic cells require T cells for functional maturation in vivo.
Volume: 11
Issue: 5
Pages: 625-36
Publication
First Author: Jin W
Year: 2009
Journal: Blood
Title: Regulation of Th17 cell differentiation and EAE induction by MAP3K NIK.
Volume: 113
Issue: 26
Pages: 6603-10
Publication
First Author: Winkels H
Year: 2021
Journal: J Immunol
Title: Thymus-Derived CD4(+)CD8(+) Cells Reside in Mediastinal Adipose Tissue and the Aortic Arch.
Volume: 207
Issue: 11
Pages: 2720-2732
Publication
First Author: Kim MS
Year: 2015
Journal: Nature
Title: Crystal structure of the V(D)J recombinase RAG1-RAG2.
Volume: 518
Issue: 7540
Pages: 507-11
Publication
First Author: Spanopoulou E
Year: 1995
Journal: Immunity
Title: Localization, interaction, and RNA binding properties of the V(D)J recombination-activating proteins RAG1 and RAG2.
Volume: 3
Issue: 6
Pages: 715-26
Publication
First Author: Cuomo CA
Year: 1996
Journal: Mol Cell Biol
Title: DNA sequence and structure requirements for cleavage of V(D)J recombination signal sequences.
Volume: 16
Issue: 10
Pages: 5683-90
Publication
First Author: McMahan CJ
Year: 1997
Journal: J Immunol
Title: Definition of a large region of RAG1 that is important for coimmunoprecipitation of RAG2.
Volume: 158
Issue: 5
Pages: 2202-10
Publication
First Author: Cebrat M
Year: 2005
Journal: Eur J Immunol
Title: Identification of a third evolutionarily conserved gene within the RAG locus and its RAG1-dependent and -independent regulation.
Volume: 35
Issue: 7
Pages: 2230-8
Publication
First Author: Kelsoe G
Year: 1999
Journal: Curr Opin Immunol
Title: V(D)J hypermutation and receptor revision: coloring outside the lines.
Volume: 11
Issue: 1
Pages: 70-5
Publication
First Author: Nacht M
Year: 1998
Journal: Cell Growth Differ
Title: V(D)J recombination is not required for the development of lymphoma in p53-deficient mice.
Volume: 9
Issue: 2
Pages: 131-8
Publication
First Author: Hagenbeek TJ
Year: 2004
Journal: J Exp Med
Title: The loss of PTEN allows TCR alphabeta lineage thymocytes to bypass IL-7 and Pre-TCR-mediated signaling.
Volume: 200
Issue: 7
Pages: 883-94
Publication
First Author: Riding AM
Year: 2022
Journal: iScience
Title: Group 3 innate lymphocytes make a distinct contribution to type 17 immunity in bladder defence.
Volume: 25
Issue: 7
Pages: 104660
Publication
First Author: Du H
Year: 2008
Journal: Mol Cell
Title: Activation of 12/23-RSS-dependent RAG cleavage by hSWI/SNF complex in the absence of transcription.
Volume: 31
Issue: 5
Pages: 641-9
Publication
First Author: Hendricks DW
Year: 2009
Journal: J Immunol
Title: Uneven colonization of the lymphoid periphery by T cells that undergo early TCR{alpha} rearrangements.
Volume: 182
Issue: 7
Pages: 4267-74
Publication
First Author: Kruschinski A
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas.
Volume: 105
Issue: 45
Pages: 17481-6
Publication
First Author: Kondo E
Year: 2003
Journal: Int Immunol
Title: Expression of recombination-activating gene in mature peripheral T cells in Peyer's patch.
Volume: 15
Issue: 3
Pages: 393-402
Publication
First Author: Curry JD
Year: 2007
Journal: J Exp Med
Title: Chromosomal reinsertion of broken RSS ends during T cell development.
Volume: 204
Issue: 10
Pages: 2293-303
Publication
First Author: Ochiai K
Year: 2012
Journal: Nat Immunol
Title: A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation.
Volume: 13
Issue: 3
Pages: 300-7
Publication
First Author: Ji Y
Year: 2010
Journal: J Exp Med
Title: Promoters, enhancers, and transcription target RAG1 binding during V(D)J recombination.
Volume: 207
Issue: 13
Pages: 2809-16
Publication
First Author: Lira A
Year: 2011
Journal: J Biol Chem
Title: Involvement of the Fc gamma receptor in a chronic N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of dopaminergic loss.
Volume: 286
Issue: 33
Pages: 28783-93
Publication  
First Author: McGowan PO
Year: 2011
Journal: Brain Res
Title: Impaired social recognition memory in recombination activating gene 1-deficient mice.
Volume: 1383
Pages: 187-95
Publication
First Author: Zhang YW
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Targeted disruption of Mig-6 in the mouse genome leads to early onset degenerative joint disease.
Volume: 102
Issue: 33
Pages: 11740-5
Publication
First Author: Lu CP
Year: 2008
Journal: Nucleic Acids Res
Title: Understanding how the V(D)J recombinase catalyzes transesterification: distinctions between DNA cleavage and transposition.
Volume: 36
Issue: 9
Pages: 2864-73
Publication
First Author: Madsen LS
Year: 1999
Journal: Nat Genet
Title: A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor.
Volume: 23
Issue: 3
Pages: 343-7
Publication
First Author: Daugherty A
Year: 1997
Journal: J Clin Invest
Title: The effects of total lymphocyte deficiency on the extent of atherosclerosis in apolipoprotein E-/- mice.
Volume: 100
Issue: 6
Pages: 1575-80
Publication
First Author: Reardon CA
Year: 2001
Journal: Arterioscler Thromb Vasc Biol
Title: Effect of immune deficiency on lipoproteins and atherosclerosis in male apolipoprotein E-deficient mice.
Volume: 21
Issue: 6
Pages: 1011-6
Publication
First Author: Chan EA
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Peripheral subnuclear positioning suppresses Tcrb recombination and segregates Tcrb alleles from RAG2.
Volume: 110
Issue: 48
Pages: E4628-37
Publication  
First Author: Safari F
Year: 2024
Journal: Life Sci Alliance
Title: SHIP1 deficiency causes inflammation-dependent retardation in skeletal growth.
Volume: 7
Issue: 5
Publication
First Author: Colucci F
Year: 2000
Journal: J Immunol
Title: A new look at Syk in alpha beta and gamma delta T cell development using chimeric mice with a low competitive hematopoietic environment.
Volume: 164
Issue: 10
Pages: 5140-5
Publication
First Author: Oshima M
Year: 2005
Journal: Cancer Res
Title: Hyperplastic gastric tumors with spasmolytic polypeptide-expressing metaplasia caused by tumor necrosis factor-alpha-dependent inflammation in cyclooxygenase-2/microsomal prostaglandin E synthase-1 transgenic mice.
Volume: 65
Issue: 20
Pages: 9147-51
Publication
First Author: Battista S
Year: 2005
Journal: Biochem J
Title: High-mobility-group A1 (HMGA1) proteins down-regulate the expression of the recombination activating gene 2 (RAG2).
Volume: 389
Issue: Pt 1
Pages: 91-7
Publication
First Author: Hennenberg EM
Year: 2017
Journal: PLoS One
Title: MDR1A deficiency restrains tumor growth in murine colitis-associated carcinogenesis.
Volume: 12
Issue: 7
Pages: e0180834
Publication  
First Author: Bonnet M
Year: 2017
Journal: Front Immunol
Title: iRAGu: A Novel Inducible and Reversible Mouse Model for Ubiquitous Recombinase Activity.
Volume: 8
Pages: 1525
Publication
First Author: Egawa T
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Transcription factor AP4 modulates reversible and epigenetic silencing of the Cd4 gene.
Volume: 108
Issue: 36
Pages: 14873-8
Publication
First Author: Hu Z
Year: 2017
Journal: Cell Rep
Title: CCR7 Modulates the Generation of Thymic Regulatory T Cells by Altering the Composition of the Thymic Dendritic Cell Compartment.
Volume: 21
Issue: 1
Pages: 168-180
Publication  
First Author: Rajakumar SA
Year: 2020
Journal: Sci Transl Med
Title: B cell acute lymphoblastic leukemia cells mediate RANK-RANKL-dependent bone destruction.
Volume: 12
Issue: 561
Publication
First Author: Abe H
Year: 2014
Journal: Int Immunol
Title: Aryl hydrocarbon receptor plays protective roles in ConA-induced hepatic injury by both suppressing IFN-γ expression and inducing IL-22.
Volume: 26
Issue: 3
Pages: 129-37
Publication
First Author: Luo XM
Year: 2012
Journal: PLoS One
Title: Recombination activating gene-2 regulates CpG-mediated interferon-α production in mouse bone marrow-derived plasmacytoid dendritic cells.
Volume: 7
Issue: 10
Pages: e47952
Publication
First Author: Soong L
Year: 1997
Journal: J Immunol
Title: Role of CD4+ T cells in pathogenesis associated with Leishmania amazonensis infection.
Volume: 158
Issue: 11
Pages: 5374-83
Publication
First Author: Sugita J
Year: 2017
Journal: Immun Inflamm Dis
Title: Contributions of Interleukin-33 and TSLP in a papain-soaked contact lens-induced mouse conjunctival inflammation model.
Volume: 5
Issue: 4
Pages: 515-525
Publication
First Author: Mallampati S
Year: 2014
Journal: Blood
Title: Integrated genetic approaches identify the molecular mechanisms of Sox4 in early B-cell development: intricate roles for RAG1/2 and CK1ε.
Volume: 123
Issue: 26
Pages: 4064-76
Publication
First Author: Chang CY
Year: 2019
Journal: Glia
Title: Glial TLR2-driven innate immune responses and CD8+ T cell activation against brain tumor.
Volume: 67
Issue: 6
Pages: 1179-1195
Publication
First Author: Kawane K
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Cytokine-dependent but acquired immunity-independent arthritis caused by DNA escaped from degradation.
Volume: 107
Issue: 45
Pages: 19432-7
Publication
First Author: Danielson M
Year: 2024
Journal: iScience
Title: Cytosolic bacterial pathogens activate TLR pathways in tumors that synergistically enhance STING agonist cancer therapies.
Volume: 27
Issue: 12
Pages: 111385
Publication
First Author: Kaur G
Year: 2023
Journal: PLoS One
Title: Helicase-like transcription factor (Hltf)-deletion activates Hmgb1-Rage axis and granzyme A-mediated killing of pancreatic β cells resulting in neonatal lethality.
Volume: 18
Issue: 8
Pages: e0286109
Publication
First Author: Lin JD
Year: 2016
Journal: PLoS Pathog
Title: Distinct Roles of Type I and Type III Interferons in Intestinal Immunity to Homologous and Heterologous Rotavirus Infections.
Volume: 12
Issue: 4
Pages: e1005600
Publication
First Author: Lee SK
Year: 2006
Journal: J Bone Miner Res
Title: T lymphocyte-deficient mice lose trabecular bone mass with ovariectomy.
Volume: 21
Issue: 11
Pages: 1704-12
Publication  
First Author: Zarnegar B
Year: 2018
Journal: Front Immunol
Title: Innate Immunity Induces the Accumulation of Lung Mast Cells During Influenza Infection.
Volume: 9
Pages: 2288
Publication
First Author: Tamehiro N
Year: 2015
Journal: PLoS One
Title: Overexpression of RhoH Permits to Bypass the Pre-TCR Checkpoint.
Volume: 10
Issue: 6
Pages: e0131047
Publication
First Author: Tsuji H
Year: 2009
Journal: Mutat Res
Title: Rag-dependent and Rag-independent mechanisms of Notch1 rearrangement in thymic lymphomas of Atm(-/-) and scid mice.
Volume: 660
Issue: 1-2
Pages: 22-32
Publication
First Author: Callén E
Year: 2007
Journal: Cell
Title: ATM prevents the persistence and propagation of chromosome breaks in lymphocytes.
Volume: 130
Issue: 1
Pages: 63-75
Publication
First Author: Ko A
Year: 2020
Journal: J Immunol
Title: TCR Repertoires of Thymic Conventional and Regulatory T Cells: Identification and Characterization of Both Unique and Shared TCR Sequences.
Volume: 204
Issue: 4
Pages: 858-867
Publication
First Author: Martins VC
Year: 2014
Journal: Nature
Title: Cell competition is a tumour suppressor mechanism in the thymus.
Volume: 509
Issue: 7501
Pages: 465-70
Publication
First Author: Burns AM
Year: 2011
Journal: J Immunol
Title: Alloantibodies prevent the induction of transplantation tolerance by enhancing alloreactive T cell priming.
Volume: 186
Issue: 1
Pages: 214-21
Publication    
First Author: Li Y
Year: 2023
Journal: Elife
Title: CCR4 and CCR7 differentially regulate thymocyte localization with distinct outcomes for central tolerance.
Volume: 12
Publication
First Author: Klinger MB
Year: 2005
Journal: Oncogene
Title: Deregulated expression of RasGRP1 initiates thymic lymphomagenesis independently of T-cell receptors.
Volume: 24
Issue: 16
Pages: 2695-704
Publication
First Author: Shinkai Y
Year: 1992
Journal: Cell
Title: RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement.
Volume: 68
Issue: 5
Pages: 855-67
Publication
First Author: Ioakeimidis F
Year: 2014
Journal: PLoS One
Title: A splicing mutation in the novel mitochondrial protein DNAJC11 causes motor neuron pathology associated with cristae disorganization, and lymphoid abnormalities in mice.
Volume: 9
Issue: 8
Pages: e104237