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Search results 1 to 100 out of 135 for Rcan1

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Type Details Score
Publication
11231093 | J:68156
First Author: Casas C
Year: 2001
Journal: Mech Dev
Title: Dscr1, a novel endogenous inhibitor of calcineurin signaling, is expressed in the primitive ventricle of the heart and during neurogenesis.
Volume: 101
Issue: 1-2
Pages: 289-92
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Publication
14738882 | J:87405
First Author: Lange AW
Year: 2004
Journal: Dev Biol
Title: DSCR1 gene expression is dependent on NFATc1 during cardiac valve formation and colocalizes with anomalous organ development in trisomy 16 mice.
Volume: 266
Issue: 2
Pages: 346-60
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Publication
12809556 | J:259128
First Author: Genescà L
Year: 2003
Journal: Biochem J
Title: Phosphorylation of calcipressin 1 increases its ability to inhibit calcineurin and decreases calcipressin half-life.
Volume: 374
Issue: Pt 2
Pages: 567-75
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Publication
17693409 | J:126797
First Author: Wu H
Year: 2007
Journal: J Biol Chem
Title: Down syndrome critical region-1 is a transcriptional target of nuclear factor of activated T cells-c1 within the endocardium during heart development.
Volume: 282
Issue: 42
Pages: 30673-9
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Publication
22546913 | J:321076
First Author: Rakowski-Anderson T
Year: 2012
Journal: Comp Med
Title: Fecal corticosterone levels in RCAN1 mutant mice.
Volume: 62
Issue: 2
Pages: 87-94
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Publication
18294449 | J:135673
First Author: Riper DV
Year: 2008
Journal: Arch Biochem Biophys
Title: Regulation of vascular function by RCAN1 (ADAPT78).
Volume: 472
Issue: 1
Pages: 43-50
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Publication
22511596 | J:184606
First Author: Martin KR
Year: 2012
Journal: Hum Mol Genet
Title: Over-expression of RCAN1 causes Down syndrome-like hippocampal deficits that alter learning and memory.
Volume: 21
Issue: 13
Pages: 3025-41
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Publication
23134420 | J:192249
First Author: Zanin MP
Year: 2013
Journal: J Neurochem
Title: RCAN1 regulates vesicle recycling and quantal release kinetics via effects on calcineurin activity.
Volume: 124
Issue: 3
Pages: 290-9
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Publication
24127415 | J:229224
First Author: Méndez-Barbero N
Year: 2013
Journal: EMBO Mol Med
Title: A major role for RCAN1 in atherosclerosis progression.
Volume: 5
Issue: 12
Pages: 1901-17
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Publication
19124655 | J:144026
First Author: Yang YJ
Year: 2009
Journal: J Exp Med
Title: Rcan1 negatively regulates Fc epsilonRI-mediated signaling and mast cell function.
Volume: 206
Issue: 1
Pages: 195-207
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Publication
21965663 | J:178153
First Author: Jung MS
Year: 2011
Journal: J Biol Chem
Title: Regulation of RCAN1 protein activity by Dyrk1A protein-mediated phosphorylation.
Volume: 286
Issue: 46
Pages: 40401-12
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Publication
30366682 | J:294873
First Author: Li H
Year: 2018
Journal: Kidney Int
Title: Epigenetic regulation of RCAN1 expression in kidney disease and its role in podocyte injury.
Volume: 94
Issue: 6
Pages: 1160-1176
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Publication
17341486 | J:132745
First Author: Porta S
Year: 2007
Journal: Hum Mol Genet
Title: RCAN1 (DSCR1) increases neuronal susceptibility to oxidative stress: a potential pathogenic process in neurodegeneration.
Volume: 16
Issue: 9
Pages: 1039-50
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Publication
30442942 | J:268611
First Author: Villahoz S
Year: 2018
Journal: Nat Commun
Title: Conditional deletion of Rcan1 predisposes to hypertension-mediated intramural hematoma and subsequent aneurysm and aortic rupture.
Volume: 9
Issue: 1
Pages: 4795
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Publication
27195491 | J:231889
First Author: Peiris H
Year: 2016
Journal: PLoS Genet
Title: A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes.
Volume: 12
Issue: 5
Pages: e1006033
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Publication
18045910 | J:127820
First Author: Hoeffer CA
Year: 2007
Journal: J Neurosci
Title: The Down syndrome critical region protein RCAN1 regulates long-term potentiation and memory via inhibition of phosphatase signaling.
Volume: 27
Issue: 48
Pages: 13161-72
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Publication
26658127 | J:228293
 
First Author: Patel A
Year: 2015
Journal: Nat Commun
Title: RCAN1 links impaired neurotrophin trafficking to aberrant development of the sympathetic nervous system in Down syndrome.
Volume: 6
Pages: 10119
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Publication
36933529 | J:355516
First Author: Pang Z
Year: 2023
Journal: Immunobiology
Title: Mice with double knockout of Egr-1 and RCAN1 exhibit reduced inflammation during Pseudomonas aeruginosa lung infection.
Volume: 228
Issue: 3
Pages: 152377
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Publication
23096997 | J:194008
First Author: Xing L
Year: 2013
Journal: Mamm Genome
Title: Creation and characterization of BAC-transgenic mice with physiological overexpression of epitope-tagged RCAN1 (DSCR1).
Volume: 24
Issue: 1-2
Pages: 30-43
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Publication
12942079 | -
First Author: Parry RV
Year: 2003
Journal: Nat Immunol
Title: Calcium-independent calcineurin regulation.
Volume: 4
Issue: 9
Pages: 821-3
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Publication
19273587 | -
First Author: Mehta S
Year: 2009
Journal: Mol Cell Biol
Title: Domain architecture of the regulators of calcineurin (RCANs) and identification of a divergent RCAN in yeast.
Volume: 29
Issue: 10
Pages: 2777-93
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Publication
28712932 | J:255405
 
First Author: Lee EH
Year: 2017
Journal: Biochem Pharmacol
Title: Pyrrolidine dithiocarbamate (PDTC) inhibits inflammatory signaling via expression of regulator of calcineurin activity 1 (RCAN1): Anti-inflammatory mechanism of PDTC through RCAN1 induction.
Volume: 143
Pages: 107-117
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Publication
35610565 | J:351595
First Author: Wong H
Year: 2022
Journal: J Neurodev Disord
Title: RCAN1 knockout and overexpression recapitulate an ensemble of rest-activity and circadian disruptions characteristic of Down syndrome, Alzheimer's disease, and normative aging.
Volume: 14
Issue: 1
Pages: 33
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Publication
23011918 | J:190956
First Author: Peiris H
Year: 2012
Journal: Endocrinology
Title: Increased expression of the glucose-responsive gene, RCAN1, causes hypoinsulinemia, β-cell dysfunction, and diabetes.
Volume: 153
Issue: 11
Pages: 5212-21
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Publication
18180251 | J:132495
First Author: Keating DJ
Year: 2008
Journal: Hum Mol Genet
Title: DSCR1/RCAN1 regulates vesicle exocytosis and fusion pore kinetics: implications for Down syndrome and Alzheimer's disease.
Volume: 17
Issue: 7
Pages: 1020-30
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Publication
23144708 | J:192360
First Author: Brait VH
Year: 2012
Journal: PLoS One
Title: Over-expression of DSCR1 protects against post-ischemic neuronal injury.
Volume: 7
Issue: 10
Pages: e47841
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Publication
27185837 | J:236816
First Author: Wang W
Year: 2016
Journal: J Cell Biol
Title: DSCR1 is required for both axonal growth cone extension and steering.
Volume: 213
Issue: 4
Pages: 451-62
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Publication
24051307 | J:205062
First Author: Shin J
Year: 2014
Journal: Cancer Lett
Title: A single extra copy of Dscr1 improves survival of mice developing spontaneous lung tumors through suppression of tumor angiogenesis.
Volume: 342
Issue: 1
Pages: 70-81
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Publication
21741935 | J:176322
First Author: Yang YJ
Year: 2011
Journal: Am J Pathol
Title: Regulator of calcineurin 1 (Rcan1) is required for the development of pulmonary eosinophilia in allergic inflammation in mice.
Volume: 179
Issue: 3
Pages: 1199-210
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Publication
34312845 | J:319467
First Author: Choi C
Year: 2021
Journal: J Pathol
Title: DSCR1 upregulation enhances dural meningeal lymphatic drainage to attenuate amyloid pathology of Alzheimer's disease.
Volume: 255
Issue: 3
Pages: 296-310
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Publication
23644448 | J:200872
First Author: Martin KR
Year: 2013
Journal: J Med Genet
Title: Upregulation of RCAN1 causes Down syndrome-like immune dysfunction.
Volume: 50
Issue: 7
Pages: 444-54
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Publication
25194880 | J:218438
First Author: Wu Y
Year: 2015
Journal: Neurobiol Aging
Title: Amyloid-β precursor protein facilitates the regulator of calcineurin 1-mediated apoptosis by downregulating proteasome subunit α type-5 and proteasome subunit β type-7.
Volume: 36
Issue: 1
Pages: 169-77
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Publication
24155299 | J:204674
First Author: Hoeffer CA
Year: 2013
Journal: J Neurosci
Title: Regulator of calcineurin 1 modulates expression of innate anxiety and anxiogenic responses to selective serotonin reuptake inhibitor treatment.
Volume: 33
Issue: 43
Pages: 16930-44
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Publication
30389725 | J:269484
 
First Author: Rotter D
Year: 2018
Journal: EMBO Rep
Title: Regulator of Calcineurin 1 helps coordinate whole-body metabolism and thermogenesis.
Volume: 19
Issue: 12
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23589609 | J:202556
First Author: Junkins RD
Year: 2013
Journal: J Immunol
Title: Regulator of calcineurin 1 suppresses inflammation during respiratory tract infections.
Volume: 190
Issue: 10
Pages: 5178-86
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Publication
24218457 | J:207132
First Author: Wu Z
Year: 2013
Journal: J Immunol
Title: Calcineurin-Rcan1 interaction contributes to stem cell factor-mediated mast cell activation.
Volume: 191
Issue: 12
Pages: 5885-94
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Publication
29799862 | J:262949
First Author: Pang Z
Year: 2018
Journal: PLoS One
Title: Regulator of calcineurin 1 differentially regulates TLR-dependent MyD88 and TRIF signaling pathways.
Volume: 13
Issue: 5
Pages: e0197491
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Publication
21364922 | J:171071
First Author: Dierssen M
Year: 2011
Journal: PLoS One
Title: Behavioral characterization of a mouse model overexpressing DSCR1/ RCAN1.
Volume: 6
Issue: 2
Pages: e17010
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Publication
26157140 | J:335066
First Author: Lee EH
Year: 2015
Journal: J Biol Chem
Title: Pituitary Adenylate Cyclase-activating Polypeptide (PACAP) Targets Down Syndrome Candidate Region 1 (DSCR1/RCAN1) to control Neuronal Differentiation.
Volume: 290
Issue: 34
Pages: 21019-21031
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Publication
24041692 | J:211430
First Author: Lee JC
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Trisomy of the Dscr1 gene suppresses early progression of pancreatic intraepithelial neoplasia driven by oncogenic Kras.
Volume: 440
Issue: 1
Pages: 50-5
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Publication
22397398 | J:318082
 
First Author: Sobrado M
Year: 2012
Journal: J Neuroinflammation
Title: Regulator of calcineurin 1 (Rcan1) has a protective role in brain ischemia/reperfusion injury.
Volume: 9
Pages: 48
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Publication
32896034 | J:328839
 
First Author: Sang XY
Year: 2020
Journal: FASEB J
Title: Regulators of calcineurin 1 deficiency attenuates tubulointerstitial fibrosis through improving mitochondrial fitness.
Volume: 34
Issue: 11
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Publication
19458618 | J:150286
First Author: Baek KH
Year: 2009
Journal: Nature
Title: Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1.
Volume: 459
Issue: 7250
Pages: 1126-30
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Publication
25783055 | J:309990
First Author: Serrano-Candelas E
Year: 2015
Journal: Biochem Biophys Res Commun
Title: RCAN 1 and 3 proteins regulate thymic positive selection.
Volume: 460
Issue: 2
Pages: 295-301
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Publication
21930771 | J:177284
First Author: Esteban V
Year: 2011
Journal: J Exp Med
Title: Regulator of calcineurin 1 mediates pathological vascular wall remodeling.
Volume: 208
Issue: 10
Pages: 2125-39
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Publication
36071051 | J:330849
First Author: Xiao JJ
Year: 2022
Journal: Cell Death Dis
Title: Regulator of calcineurin 1 deletion attenuates mitochondrial dysfunction and apoptosis in acute kidney injury through JNK/Mff signaling pathway.
Volume: 13
Issue: 9
Pages: 774
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Publication
24838101 | J:225630
 
First Author: Rotter D
Year: 2014
Journal: J Mol Cell Cardiol
Title: Calcineurin and its regulator, RCAN1, confer time-of-day changes in susceptibility of the heart to ischemia/reperfusion.
Volume: 74
Pages: 103-11
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Publication
19136967 | J:158070
First Author: Liu Q
Year: 2009
Journal: Nat Cell Biol
Title: Interaction between TAK1-TAB1-TAB2 and RCAN1-calcineurin defines a signalling nodal control point.
Volume: 11
Issue: 2
Pages: 154-61
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Publication
18319259 | J:137088
First Author: Belmont PJ
Year: 2008
Journal: J Biol Chem
Title: Coordination of growth and endoplasmic reticulum stress signaling by regulator of calcineurin 1 (RCAN1), a novel ATF6-inducible gene.
Volume: 283
Issue: 20
Pages: 14012-21
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Publication
12925851 | J:85148
First Author: Ryeom S
Year: 2003
Journal: Nat Immunol
Title: The threshold pattern of calcineurin-dependent gene expression is altered by loss of the endogenous inhibitor calcipressin.
Volume: 4
Issue: 9
Pages: 874-81
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18455125 | J:134771
First Author: Ryeom S
Year: 2008
Journal: Cancer Cell
Title: Targeted deletion of the calcineurin inhibitor DSCR1 suppresses tumor growth.
Volume: 13
Issue: 5
Pages: 420-31
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Publication
23954784 | J:202765
First Author: Minami T
Year: 2013
Journal: Cell Rep
Title: The calcineurin-NFAT-angiopoietin-2 signaling axis in lung endothelium is critical for the establishment of lung metastases.
Volume: 4
Issue: 4
Pages: 709-23
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Publication
36450444 | J:331957
 
First Author: Choi C
Year: 2023
Journal: Life Sci Alliance
Title: DSCR1 deficiency ameliorates the Aβ pathology of Alzheimer's disease by enhancing microglial activity.
Volume: 6
Issue: 2
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16198305 | J:101936
First Author: Kluetzman KS
Year: 2005
Journal: Biochem Biophys Res Commun
Title: DSCR1 (ADAPT78) lethality: evidence for a protective effect of trisomy 21 genes?
Volume: 337
Issue: 2
Pages: 595-601
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32787520 | J:318567
First Author: Muramatsu M
Year: 2020
Journal: Arterioscler Thromb Vasc Biol
Title: Loss of Down Syndrome Critical Region-1 Mediated-Hypercholesterolemia Accelerates Corneal Opacity Via Pathological Neovessel Formation.
Volume: 40
Issue: 10
Pages: 2425-2439
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Publication
- | J:68271
   
First Author: Fuentes JJ
Year: 2000
Journal: GenBank Submission
Title: Mus musculus calcineurin inhibitor mRNA, complete cds
Pages: AF263240
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Publication
- | J:68272
   
First Author: Fuentes JJ
Year: 2000
Journal: GenBank Submission
Title: Mus musculus calcineurin inhibitor mRNA, complete cds
Pages: AF263239
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Publication
24021800 | J:201827
 
First Author: Song WJ
Year: 2013
Journal: Neurosci Lett
Title: Dyrk1A-mediated phosphorylation of RCAN1 promotes the formation of insoluble RCAN1 aggregates.
Volume: 554
Pages: 135-40
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10722714 | J:64822
First Author: Rothermel B
Year: 2000
Journal: J Biol Chem
Title: A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling.
Volume: 275
Issue: 12
Pages: 8719-25
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19620774 | J:152536
First Author: Minami T
Year: 2009
Journal: J Clin Invest
Title: The Down syndrome critical region gene 1 short variant promoters direct vascular bed-specific gene expression during inflammation in mice.
Volume: 119
Issue: 8
Pages: 2257-70
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11080588 | J:65855
First Author: Strippoli P
Year: 2000
Journal: Gene
Title: The murine DSCR1-like (Down syndrome candidate region 1) gene family: conserved synteny with the human orthologous genes.
Volume: 257
Issue: 2
Pages: 223-32
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Publication
22863780 | J:188613
First Author: Wang W
Year: 2012
Journal: EMBO J
Title: DSCR1 interacts with FMRP and is required for spine morphogenesis and local protein synthesis.
Volume: 31
Issue: 18
Pages: 3655-66
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Publication
15906378 | J:98789
First Author: Lange AW
Year: 2005
Journal: Dev Dyn
Title: Restoration of DSCR1 to disomy in the trisomy 16 mouse model of Down syndrome does not correct cardiac or craniofacial development anomalies.
Volume: 233
Issue: 3
Pages: 954-63
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Publication
25009293 | J:216706
First Author: Zhou AY
Year: 2014
Journal: Mol Cancer Res
Title: Cyclosporin A promotes tumor angiogenesis in a calcineurin-independent manner by increasing mitochondrial reactive oxygen species.
Volume: 12
Issue: 11
Pages: 1663-76
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10756093 | J:61529
First Author: Strippoli P
Year: 2000
Journal: Genomics
Title: A new gene family including DSCR1 (Down Syndrome Candidate Region 1) and ZAKI-4: characterization from yeast to human and identification of DSCR1-like 2, a novel human member (DSCR1L2).
Volume: 64
Issue: 3
Pages: 252-63
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16415348 | J:110583
First Author: Abbasi S
Year: 2006
Journal: J Biol Chem
Title: Protein kinase-mediated regulation of calcineurin through the phosphorylation of modulatory calcineurin-interacting protein 1.
Volume: 281
Issue: 12
Pages: 7717-26
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17595344 | J:122065
First Author: Davies KJ
Year: 2007
Journal: FASEB J
Title: Renaming the DSCR1/Adapt78 gene family as RCAN: regulators of calcineurin.
Volume: 21
Issue: 12
Pages: 3023-8
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Publication
33895138 | J:305879
   
First Author: Muramatsu M
Year: 2021
Journal: J Biol Chem
Title: Loss of Down syndrome critical region-1 leads to cholesterol metabolic dysfunction that exaggerates hypercholesterolemia in ApoE-null background.
Pages: 100697
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16648267 | J:109586
First Author: Sanna B
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Modulatory calcineurin-interacting proteins 1 and 2 function as calcineurin facilitators in vivo.
Volume: 103
Issue: 19
Pages: 7327-32
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12515860 | J:81417
First Author: Vega RB
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Dual roles of modulatory calcineurin-interacting protein 1 in cardiac hypertrophy.
Volume: 100
Issue: 2
Pages: 669-74
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20371871 | J:163881
First Author: Oh M
Year: 2010
Journal: J Biol Chem
Title: The CCAAT/enhancer binding protein beta (C/EBPbeta) cooperates with NFAT to control expression of the calcineurin regulatory protein RCAN1-4.
Volume: 285
Issue: 22
Pages: 16623-31
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21947295 | J:189471
First Author: Chen S
Year: 2011
Journal: Circulation
Title: Cardiomyocyte-specific deletion of the vitamin D receptor gene results in cardiac hypertrophy.
Volume: 124
Issue: 17
Pages: 1838-47
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28172997 | J:241781
First Author: McElyea SD
Year: 2016
Journal: Hum Mol Genet
Title: Influence of prenatal EGCG treatment and Dyrk1a dosage reduction on craniofacial features associated with Down syndrome.
Volume: 25
Issue: 22
Pages: 4856-4869
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15866158 | J:105135
First Author: Mammucari C
Year: 2005
Journal: Dev Cell
Title: Integration of Notch 1 and calcineurin/NFAT signaling pathways in keratinocyte growth and differentiation control.
Volume: 8
Issue: 5
Pages: 665-76
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Publication
32499640 | J:291601
First Author: Nguyen NUN
Year: 2020
Journal: Nature
Title: A calcineurin-Hoxb13 axis regulates growth mode of mammalian cardiomyocytes.
Volume: 582
Issue: 7811
Pages: 271-276
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25556111 | J:217672
 
First Author: Blazek JD
Year: 2015
Journal: Mech Dev
Title: Abnormal mineralization of the Ts65Dn Down syndrome mouse appendicular skeleton begins during embryonic development in a Dyrk1a-independent manner.
Volume: 136
Pages: 133-42
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24352425 | J:205486
First Author: Kurabayashi N
Year: 2013
Journal: Genes Dev
Title: Increased dosage of DYRK1A and DSCR1 delays neuronal differentiation in neocortical progenitor cells.
Volume: 27
Issue: 24
Pages: 2708-21
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25261685 | J:220406
 
First Author: Ishihara K
Year: 2014
Journal: Neuroscience
Title: Comparative proteomic profiling reveals aberrant cell proliferation in the brain of embryonic Ts1Cje, a mouse model of Down syndrome.
Volume: 281
Pages: 1-15
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Publication
33172478 | J:313510
First Author: Denkena J
Year: 2020
Journal: Mol Brain
Title: Neuronal activity regulates alternative exon usage.
Volume: 13
Issue: 1
Pages: 148
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16554754 | J:109139
First Author: Arron JR
Year: 2006
Journal: Nature
Title: NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21.
Volume: 441
Issue: 7093
Pages: 595-600
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16024798 | J:100019
First Author: Oh M
Year: 2005
Journal: Mol Cell Biol
Title: Calcineurin is necessary for the maintenance but not embryonic development of slow muscle fibers.
Volume: 25
Issue: 15
Pages: 6629-38
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26430214 | J:233771
First Author: Chen HH
Year: 2015
Journal: J Cell Sci
Title: NRIP is newly identified as a Z-disc protein, activating calmodulin signaling for skeletal muscle contraction and regeneration.
Volume: 128
Issue: 22
Pages: 4196-209
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33773996 | J:304446
 
First Author: Beckert V
Year: 2021
Journal: J Mol Cell Cardiol
Title: Creld1 regulates myocardial development and function.
Volume: 156
Pages: 45-56
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Publication
24697899 | J:313967
First Author: Mass E
Year: 2014
Journal: Dev Cell
Title: Murine Creld1 controls cardiac development through activation of calcineurin/NFATc1 signaling.
Volume: 28
Issue: 6
Pages: 711-26
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Publication
36899856 | J:334092
 
First Author: Broadway-Stringer S
Year: 2023
Journal: Cells
Title: Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2.
Volume: 12
Issue: 5
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Publication
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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