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Search results 1 to 100 out of 212 for Scn5a

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Category: Publication
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Type Details Score
Publication
30371314 | J:279087
First Author: Pang PD
Year: 2018
Journal: J Am Heart Assoc
Title: CRISPR -Mediated Expression of the Fetal Scn5a Isoform in Adult Mice Causes Conduction Defects and Arrhythmias.
Volume: 7
Issue: 19
Pages: e010393
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Publication
22728936 | J:190765
First Author: Arnolds DE
Year: 2012
Journal: J Clin Invest
Title: TBX5 drives Scn5a expression to regulate cardiac conduction system function.
Volume: 122
Issue: 7
Pages: 2509-18
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Publication
21824921 | J:189389
First Author: Watanabe H
Year: 2011
Journal: Circulation
Title: Striking In vivo phenotype of a disease-associated human SCN5A mutation producing minimal changes in vitro.
Volume: 124
Issue: 9
Pages: 1001-11
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Publication
24642470 | J:209588
First Author: van den Boogaard M
Year: 2014
Journal: J Clin Invest
Title: A common genetic variant within SCN10A modulates cardiac SCN5A expression.
Volume: 124
Issue: 4
Pages: 1844-52
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Publication
17118339 | J:116497
First Author: Yong SL
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Characterization of the cardiac sodium channel SCN5A mutation, N1325S, in single murine ventricular myocytes.
Volume: 352
Issue: 2
Pages: 378-83
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Publication
17157817 | J:116505
First Author: Tian XL
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Optical mapping of ventricular arrhythmias in LQTS mice with SCN5A mutation N1325S.
Volume: 352
Issue: 4
Pages: 879-83
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Publication
27063795 | J:236898
 
First Author: Freyermuth F
Year: 2016
Journal: Nat Commun
Title: Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy.
Volume: 7
Pages: 11067
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Publication
26392562 | J:227075
First Author: Musa H
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: SCN5A variant that blocks fibroblast growth factor homologous factor regulation causes human arrhythmia.
Volume: 112
Issue: 40
Pages: 12528-33
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Publication
14736542 | J:134567
First Author: Tian XL
Year: 2004
Journal: Cardiovasc Res
Title: Mechanisms by which SCN5A mutation N1325S causes cardiac arrhythmias and sudden death in vivo.
Volume: 61
Issue: 2
Pages: 256-67
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Publication
17300750 | J:118632
First Author: Zhang T
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Cardiac-specific overexpression of SCN5A gene leads to shorter P wave duration and PR interval in transgenic mice.
Volume: 355
Issue: 2
Pages: 444-50
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Publication
16403066 | J:127879
First Author: Head CE
Year: 2005
Journal: J Cardiovasc Electrophysiol
Title: Paced electrogram fractionation analysis of arrhythmogenic tendency in DeltaKPQ Scn5a mice.
Volume: 16
Issue: 12
Pages: 1329-40
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Publication
31125670 | J:333144
First Author: Daniel LL
Year: 2019
Journal: Heart Rhythm
Title: SCN5A variant R222Q generated abnormal changes in cardiac sodium current and action potentials in murine myocytes and Purkinje cells.
Volume: 16
Issue: 11
Pages: 1676-1685
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Publication
28779003 | J:342506
First Author: Shen C
Year: 2017
Journal: J Med Genet
Title: Novel idiopathic DCM-related SCN5A variants localised in DI-S4 predispose electrical disorders by reducing peak sodium current density.
Volume: 54
Issue: 11
Pages: 762-770
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Publication
12650887 | J:162749
First Author: Fabritz L
Year: 2003
Journal: Cardiovasc Res
Title: Effect of pacing and mexiletine on dispersion of repolarisation and arrhythmias in DeltaKPQ SCN5A (long QT3) mice.
Volume: 57
Issue: 4
Pages: 1085-93
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Publication
17110414 | J:134138
First Author: Thomas G
Year: 2007
Journal: J Physiol
Title: Effects of L-type Ca2+ channel antagonism on ventricular arrhythmogenesis in murine hearts containing a modification in the Scn5a gene modelling human long QT syndrome 3.
Volume: 578
Issue: Pt 1
Pages: 85-97
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Publication
21097662 | J:166438
First Author: Martin CA
Year: 2011
Journal: Am J Physiol Heart Circ Physiol
Title: Spatial and temporal heterogeneities are localized to the right ventricular outflow tract in a heterozygotic Scn5a mouse model.
Volume: 300
Issue: 2
Pages: H605-16
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Publication
34248669 | J:312594
 
First Author: Schroder EA
Year: 2021
Journal: Front Physiol
Title: Cardiomyocyte Deletion of Bmal1 Exacerbates QT- and RR-Interval Prolongation in Scn5a +/ΔKPQ Mice.
Volume: 12
Pages: 681011
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Publication
31666509 | J:281596
First Author: Man JCK
Year: 2019
Journal: Nat Commun
Title: An enhancer cluster controls gene activity and topology of the SCN5A-SCN10A locus in vivo.
Volume: 10
Issue: 1
Pages: 4943
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Publication
26595809 | J:229825
First Author: Wan E
Year: 2016
Journal: J Clin Invest
Title: Aberrant sodium influx causes cardiomyopathy and atrial fibrillation in mice.
Volume: 126
Issue: 1
Pages: 112-22
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Publication
8541846 | J:45859
First Author: Wang Q
Year: 1995
Journal: Hum Mol Genet
Title: Cardiac sodium channel mutations in patients with long QT syndrome, an inherited cardiac arrhythmia.
Volume: 4
Issue: 9
Pages: 1603-7
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Publication
11533705 | J:71542
First Author: Nuyens D
Year: 2001
Journal: Nat Med
Title: Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome.
Volume: 7
Issue: 9
Pages: 1021-7
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Publication
22562703 | J:202661
First Author: Lowe JS
Year: 2012
Journal: Cardiovasc Res
Title: Increased late sodium current contributes to long QT-related arrhythmia susceptibility in female mice.
Volume: 95
Issue: 3
Pages: 300-7
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Publication
36782060 | J:360862
First Author: Weigel B
Year: 2023
Journal: Mol Psychiatry
Title: MYT1L haploinsufficiency in human neurons and mice causes autism-associated phenotypes that can be reversed by genetic and pharmacologic intervention.
Volume: 28
Issue: 5
Pages: 2122-2135
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28339646 | J:260835
First Author: Derangeon M
Year: 2017
Journal: Cardiovasc Res
Title: Transforming growth factor β receptor inhibition prevents ventricular fibrosis in a mouse model of progressive cardiac conduction disease.
Volume: 113
Issue: 5
Pages: 464-474
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16172272 | J:116845
First Author: van Veen TA
Year: 2005
Journal: Circulation
Title: Impaired impulse propagation in Scn5a-knockout mice: combined contribution of excitability, connexin expression, and tissue architecture in relation to aging.
Volume: 112
Issue: 13
Pages: 1927-35
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17083109 | J:115269
First Author: Liu K
Year: 2006
Journal: Genesis
Title: Recombinase-mediated cassette exchange to rapidly and efficiently generate mice with human cardiac sodium channels.
Volume: 44
Issue: 11
Pages: 556-64
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29457789 | J:260801
First Author: Zhang X
Year: 2018
Journal: J Clin Invest
Title: A common variant alters SCN5A-miR-24 interaction and associates with heart failure mortality.
Volume: 128
Issue: 3
Pages: 1154-1163
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Publication
20110334 | J:175883
First Author: Fabritz L
Year: 2010
Journal: Cardiovasc Res
Title: Autonomic modulation and antiarrhythmic therapy in a model of long QT syndrome type 3.
Volume: 87
Issue: 1
Pages: 60-72
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Publication
17145985 | J:128657
First Author: Remme CA
Year: 2006
Journal: Circulation
Title: Overlap syndrome of cardiac sodium channel disease in mice carrying the equivalent mutation of human SCN5A-1795insD.
Volume: 114
Issue: 24
Pages: 2584-94
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Publication
31614475 | J:290393
 
First Author: Casini S
Year: 2019
Journal: Int J Mol Sci
Title: Functional Consequences of the SCN5A-p.Y1977N Mutation within the PY Ubiquitylation Motif: Discrepancy between HEK293 Cells and Transgenic Mice.
Volume: 20
Issue: 20
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Publication
20042427 | J:184957
First Author: Valdivia CR
Year: 2010
Journal: Cardiovasc Res
Title: Loss-of-function mutation of the SCN3B-encoded sodium channel {beta}3 subunit associated with a case of idiopathic ventricular fibrillation.
Volume: 86
Issue: 3
Pages: 392-400
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Publication
20174578 | J:301953
First Author: Leoni AL
Year: 2010
Journal: PLoS One
Title: Variable Na(v)1.5 protein expression from the wild-type allele correlates with the penetrance of cardiac conduction disease in the Scn5a(+/-) mouse model.
Volume: 5
Issue: 2
Pages: e9298
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29267949 | J:268240
First Author: Kelly A
Year: 2018
Journal: Cardiovasc Res
Title: Normal interventricular differences in tissue architecture underlie right ventricular susceptibility to conduction abnormalities in a mouse model of Brugada syndrome.
Volume: 114
Issue: 5
Pages: 724-736
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21672931 | J:191708
First Author: Lemoine MD
Year: 2011
Journal: Cardiovasc Res
Title: Arrhythmogenic left atrial cellular electrophysiology in a murine genetic long QT syndrome model.
Volume: 92
Issue: 1
Pages: 67-74
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Publication
22287583 | J:186583
First Author: Wu J
Year: 2012
Journal: Am J Physiol Heart Circ Physiol
Title: Altered sinoatrial node function and intra-atrial conduction in murine gain-of-function Scn5a+/ΔKPQ hearts suggest an overlap syndrome.
Volume: 302
Issue: 7
Pages: H1510-23
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30144447 | J:266290
 
First Author: Montnach J
Year: 2018
Journal: J Mol Cell Cardiol
Title: Arrhythmias precede cardiomyopathy and remodeling of Ca2+ handling proteins in a novel model of long QT syndrome.
Volume: 123
Pages: 13-25
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38214908 | J:345780
First Author: Blair GA
Year: 2024
Journal: Am J Physiol Heart Circ Physiol
Title: Mannitol and hyponatremia regulate cardiac ventricular conduction in the context of sodium channel loss of function.
Volume: 326
Issue: 3
Pages: H724-H734
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21566215 | J:185686
First Author: Atack TC
Year: 2011
Journal: Circ Res
Title: Informatic and functional approaches to identifying a regulatory region for the cardiac sodium channel.
Volume: 109
Issue: 1
Pages: 38-46
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23364267 | J:198010
First Author: Schroder EA
Year: 2013
Journal: Am J Physiol Cell Physiol
Title: The cardiomyocyte molecular clock, regulation of Scn5a, and arrhythmia susceptibility.
Volume: 304
Issue: 10
Pages: C954-65
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18591664 | J:198910
First Author: Ueda K
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Syntrophin mutation associated with long QT syndrome through activation of the nNOS-SCN5A macromolecular complex.
Volume: 105
Issue: 27
Pages: 9355-60
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15932895 | J:151611
First Author: Lei M
Year: 2005
Journal: J Physiol
Title: Sinus node dysfunction following targeted disruption of the murine cardiac sodium channel gene Scn5a.
Volume: 567
Issue: Pt 2
Pages: 387-400
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21673812 | J:174959
First Author: Stein M
Year: 2011
Journal: PLoS One
Title: A 50% reduction of excitability but not of intercellular coupling affects conduction velocity restitution and activation delay in the mouse heart.
Volume: 6
Issue: 6
Pages: e20310
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32778883 | J:320917
First Author: Rivaud MR
Year: 2020
Journal: Europace
Title: Functional modulation of atrio-ventricular conduction by enhanced late sodium current and calcium-dependent mechanisms in Scn5a1798insD/+ mice.
Volume: 22
Issue: 10
Pages: 1579-1589
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Publication
23872634 | J:280846
First Author: Bezzina CR
Year: 2013
Journal: Nat Genet
Title: Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death.
Volume: 45
Issue: 9
Pages: 1044-9
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19389723 | J:162186
First Author: Stein M
Year: 2009
Journal: Cardiovasc Res
Title: Combined reduction of intercellular coupling and membrane excitability differentially affects transverse and longitudinal cardiac conduction.
Volume: 83
Issue: 1
Pages: 52-60
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Publication
26187182 | J:239053
First Author: Glynn P
Year: 2015
Journal: Circulation
Title: Voltage-Gated Sodium Channel Phosphorylation at Ser571 Regulates Late Current, Arrhythmia, and Cardiac Function In Vivo.
Volume: 132
Issue: 7
Pages: 567-77
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24687990 | J:216531
First Author: Hartman ME
Year: 2014
Journal: FASEB J
Title: Myocardial deletion of transcription factor CHF1/Hey2 results in altered myocyte action potential and mild conduction system expansion but does not alter conduction system function or promote spontaneous arrhythmias.
Volume: 28
Issue: 7
Pages: 3007-15
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23661717 | J:213278
First Author: Boukens BJ
Year: 2013
Journal: Circ Res
Title: Reduced sodium channel function unmasks residual embryonic slow conduction in the adult right ventricular outflow tract.
Volume: 113
Issue: 2
Pages: 137-41
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18178574 | J:161910
First Author: Domínguez JN
Year: 2008
Journal: Cardiovasc Res
Title: Tissue distribution and subcellular localization of the cardiac sodium channel during mouse heart development.
Volume: 78
Issue: 1
Pages: 45-52
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19255801 | J:152116
First Author: Remme CA
Year: 2009
Journal: Basic Res Cardiol
Title: The cardiac sodium channel displays differential distribution in the conduction system and transmural heterogeneity in the murine ventricular myocardium.
Volume: 104
Issue: 5
Pages: 511-22
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Publication
24956219 | J:323796
 
First Author: Cai B
Year: 2014
Journal: J Mol Cell Cardiol
Title: Deletion of FoxO1 leads to shortening of QRS by increasing Na(+) channel activity through enhanced expression of both cardiac NaV1.5 and β3 subunit.
Volume: 74
Pages: 297-306
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- | J:2513
First Author: Klocke R
Year: 1992
Journal: Mouse Genome
Title: Chromosomal mapping of muscle-expressed sodium channel genes in the mouse
Volume: 90
Issue: 3
Pages: 433-35
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27766308 | J:243706
 
First Author: Choy L
Year: 2016
Journal: Int J Cardiol Heart Vasc
Title: Cardiac disease and arrhythmogenesis: Mechanistic insights from mouse models.
Volume: 12
Pages: 1-10
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11972032 | J:76331
First Author: Papadatos GA
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a.
Volume: 99
Issue: 9
Pages: 6210-5
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31291141 | J:279268
First Author: Finlay M
Year: 2019
Journal: Am J Physiol Cell Physiol
Title: Autonomic modulation of the electrical substrate in mice haploinsufficient for cardiac sodium channels: a model of the Brugada syndrome.
Volume: 317
Issue: 3
Pages: C576-C583
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15809371 | J:109689
First Author: Royer A
Year: 2005
Journal: Circulation
Title: Mouse model of SCN5A-linked hereditary Lenègre's disease: age-related conduction slowing and myocardial fibrosis.
Volume: 111
Issue: 14
Pages: 1738-46
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23836691 | J:214178
First Author: Matthews GD
Year: 2013
Journal: J Physiol
Title: Action potential wavelength restitution predicts alternans and arrhythmia in murine Scn5a(+/-) hearts.
Volume: 591
Issue: 17
Pages: 4167-88
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19745168 | J:169955
First Author: Liu M
Year: 2009
Journal: Circ Res
Title: Cardiac Na+ current regulation by pyridine nucleotides.
Volume: 105
Issue: 8
Pages: 737-45
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17082480 | J:129060
First Author: Fredj S
Year: 2006
Journal: Circ Res
Title: Altered Na+ channels promote pause-induced spontaneous diastolic activity in long QT syndrome type 3 myocytes.
Volume: 99
Issue: 11
Pages: 1225-32
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25343952 | J:220782
First Author: Schroder EA
Year: 2014
Journal: Am J Physiol Heart Circ Physiol
Title: Light phase-restricted feeding slows basal heart rate to exaggerate the type-3 long QT syndrome phenotype in mice.
Volume: 307
Issue: 12
Pages: H1777-85
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28894151 | J:255390
First Author: Chadda KR
Year: 2017
Journal: Sci Rep
Title: The effects of ageing and adrenergic challenge on electrocardiographic phenotypes in a murine model of long QT syndrome type 3.
Volume: 7
Issue: 1
Pages: 11070
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17023504 | J:134141
First Author: Stokoe KS
Year: 2007
Journal: J Physiol
Title: Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/Delta murine hearts modelling long QT syndrome 3.
Volume: 578
Issue: Pt 1
Pages: 69-84
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22842345 | J:187595
First Author: Lo WL
Year: 2012
Journal: Nat Immunol
Title: A voltage-gated sodium channel is essential for the positive selection of CD4(+) T cells.
Volume: 13
Issue: 9
Pages: 880-7
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24705556 | J:212400
First Author: Zhang Y
Year: 2014
Journal: Am J Physiol Heart Circ Physiol
Title: Measurement and interpretation of electrocardiographic QT intervals in murine hearts.
Volume: 306
Issue: 11
Pages: H1553-7
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20854825 | J:171025
First Author: Scicluna BP
Year: 2011
Journal: J Mol Cell Cardiol
Title: Quantitative trait loci for electrocardiographic parameters and arrhythmia in the mouse.
Volume: 50
Issue: 3
Pages: 380-9
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28430892 | J:263303
First Author: Portero V
Year: 2017
Journal: Cardiovasc Res
Title: Anti-arrhythmic potential of the late sodium current inhibitor GS-458967 in murine Scn5a-1798insD+/- and human SCN5A-1795insD+/- iPSC-derived cardiomyocytes.
Volume: 113
Issue: 7
Pages: 829-838
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19407241 | J:172111
First Author: Remme CA
Year: 2009
Journal: Circ Res
Title: Genetically determined differences in sodium current characteristics modulate conduction disease severity in mice with cardiac sodium channelopathy.
Volume: 104
Issue: 11
Pages: 1283-92
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30194875 | J:266988
First Author: Pappalardo LW
Year: 2018
Journal: Glia
Title: Nav1.5 in astrocytes plays a sex-specific role in clinical outcomes in a mouse model of multiple sclerosis.
Volume: 66
Issue: 10
Pages: 2174-2187
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24895455 | J:224433
First Author: Shy D
Year: 2014
Journal: Circulation
Title: PDZ domain-binding motif regulates cardiomyocyte compartment-specific NaV1.5 channel expression and function.
Volume: 130
Issue: 2
Pages: 147-60
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29932771 | J:267177
First Author: Howard T
Year: 2018
Journal: Am J Physiol Heart Circ Physiol
Title: CaMKII-dependent late Na+ current increases electrical dispersion and arrhythmia in ischemia-reperfusion.
Volume: 315
Issue: 4
Pages: H794-H801
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32886003 | J:301328
First Author: Comelli M
Year: 2020
Journal: Am J Physiol Heart Circ Physiol
Title: Rhythm dynamics of the aging heart: an experimental study using conscious, restrained mice.
Volume: 319
Issue: 4
Pages: H893-H905
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20549739 | J:161206
First Author: Chen F
Year: 2010
Journal: Dev Dyn
Title: Atrioventricular conduction and arrhythmias at the initiation of beating in embryonic mouse hearts.
Volume: 239
Issue: 7
Pages: 1941-9
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21378142 | J:170460
First Author: Martin CA
Year: 2011
Journal: Am J Physiol Heart Circ Physiol
Title: Mapping of reentrant spontaneous polymorphic ventricular tachycardia in a Scn5a+/- mouse model.
Volume: 300
Issue: 5
Pages: H1853-62
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- | J:65942
   
First Author: Zimmer T
Year: 2000
Journal: GenBank Submission
Title: Mus musculus mRNA for voltage-gated sodium channel (Scn5a gene)
Pages: AJ271477
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18184654 | J:184959
First Author: Wu L
Year: 2008
Journal: J Biol Chem
Title: Identification of a new co-factor, MOG1, required for the full function of cardiac sodium channel Nav 1.5.
Volume: 283
Issue: 11
Pages: 6968-78
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23420830 | J:200449
First Author: Chakrabarti S
Year: 2013
Journal: Circ Arrhythm Electrophysiol
Title: MOG1 rescues defective trafficking of Na(v)1.5 mutations in Brugada syndrome and sick sinus syndrome.
Volume: 6
Issue: 2
Pages: 392-401
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16636276 | J:109589
First Author: Franken P
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: NPAS2 as a transcriptional regulator of non-rapid eye movement sleep: genotype and sex interactions.
Volume: 103
Issue: 18
Pages: 7118-23
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15047701 | J:90731
First Author: Kerr NC
Year: 2004
Journal: J Biol Chem
Title: Novel isoforms of the sodium channels Nav1.8 and Nav1.5 are produced by a conserved mechanism in mouse and rat.
Volume: 279
Issue: 23
Pages: 24826-33
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11834499 | J:108205
First Author: Zimmer T
Year: 2002
Journal: Am J Physiol Heart Circ Physiol
Title: Mouse heart Na+ channels: primary structure and function of two isoforms and alternatively spliced variants.
Volume: 282
Issue: 3
Pages: H1007-17
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Publication
23236294 | J:194852
First Author: Lodder EM
Year: 2012
Journal: PLoS Genet
Title: Dissection of a quantitative trait locus for PR interval duration identifies Tnni3k as a novel modulator of cardiac conduction.
Volume: 8
Issue: 12
Pages: e1003113
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Publication
31333492 | J:286963
 
First Author: Rougier JS
Year: 2019
Journal: Front Physiol
Title: A Distinct Pool of Nav1.5 Channels at the Lateral Membrane of Murine Ventricular Cardiomyocytes.
Volume: 10
Pages: 834
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Publication
30602331 | J:320791
First Author: El Refaey M
Year: 2019
Journal: Circ Res
Title: Protein Phosphatase 2A Regulates Cardiac Na+ Channels.
Volume: 124
Issue: 5
Pages: 737-746
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Publication
16728661 | J:122624
First Author: Allouis M
Year: 2006
Journal: Circ Res
Title: 14-3-3 is a regulator of the cardiac voltage-gated sodium channel Nav1.5.
Volume: 98
Issue: 12
Pages: 1538-46
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Publication
19943616 | J:221558
First Author: Ziane R
Year: 2010
Journal: Biochemistry
Title: Cell membrane expression of cardiac sodium channel Na(v)1.5 is modulated by alpha-actinin-2 interaction.
Volume: 49
Issue: 1
Pages: 166-78
•
•
•
•
•
Publication
21817159 | J:187546
First Author: Wang C
Year: 2011
Journal: Circ Res
Title: Fibroblast growth factor homologous factor 13 regulates Na+ channels and conduction velocity in murine hearts.
Volume: 109
Issue: 7
Pages: 775-82
•
•
•
•
•
Publication
17095567 | J:140608
First Author: Thomas G
Year: 2007
Journal: J Physiol
Title: Mechanisms of ventricular arrhythmogenesis in mice following targeted disruption of KCNE1 modelling long QT syndrome 5.
Volume: 578
Issue: Pt 1
Pages: 99-114
•
•
•
•
•
Publication
38322613 | J:345880
 
First Author: Ferrand MC
Year: 2024
Journal: Front Physiol
Title: Intracardiac electrophysiology to characterize susceptibility to ventricular arrhythmias in murine models.
Volume: 15
Pages: 1326663
•
•
•
•
•
Publication
26289036 | J:282759
 
First Author: Iyer V
Year: 2015
Journal: Sci Rep
Title: Purkinje Cells as Sources of Arrhythmias in Long QT Syndrome Type 3.
Volume: 5
Pages: 13287
•
•
•
•
•
Publication
23723061 | J:218654
First Author: King JH
Year: 2013
Journal: Cardiovasc Res
Title: Loss of Nav1.5 expression and function in murine atria containing the RyR2-P2328S gain-of-function mutation.
Volume: 99
Issue: 4
Pages: 751-9
•
•
•
•
•
Publication
29306897 | J:255706
 
First Author: Huang L
Year: 2018
Journal: J Am Heart Assoc
Title: Critical Roles of Xirp Proteins in Cardiac Conduction and Their Rare Variants Identified in Sudden Unexplained Nocturnal Death Syndrome and Brugada Syndrome in Chinese Han Population.
Volume: 7
Issue: 1
•
•
•
•
•
Publication
25139742 | J:230223
First Author: Agullo-Pascual E
Year: 2014
Journal: Cardiovasc Res
Title: Super-resolution imaging reveals that loss of the C-terminus of connexin43 limits microtubule plus-end capture and NaV1.5 localization at the intercalated disc.
Volume: 104
Issue: 2
Pages: 371-81
•
•
•
•
•
Publication
24719102 | J:208111
First Author: Osorio N
Year: 2014
Journal: J Neurosci
Title: Specialized functions of Nav1.5 and Nav1.9 channels in electrogenesis of myenteric neurons in intact mouse ganglia.
Volume: 34
Issue: 15
Pages: 5233-44
•
•
•
•
•
Publication
28882890 | J:246419
First Author: Burel S
Year: 2017
Journal: J Biol Chem
Title: C-terminal phosphorylation of NaV1.5 impairs FGF13-dependent regulation of channel inactivation.
Volume: 292
Issue: 42
Pages: 17431-17448
•
•
•
•
•
Publication
21164104 | J:183504
First Author: Petitprez S
Year: 2011
Journal: Circ Res
Title: SAP97 and dystrophin macromolecular complexes determine two pools of cardiac sodium channels Nav1.5 in cardiomyocytes.
Volume: 108
Issue: 3
Pages: 294-304
•
•
•
•
•
Publication
15546876 | J:105049
First Author: Jones GL
Year: 2005
Journal: J Biol Chem
Title: A functional analysis of mouse models of cardiac disease through metabolic profiling.
Volume: 280
Issue: 9
Pages: 7530-9
•
•
•
•
•
Publication
20952415 | J:186038
First Author: Albesa M
Year: 2011
Journal: Cardiovasc Res
Title: Regulation of the cardiac sodium channel Nav1.5 by utrophin in dystrophin-deficient mice.
Volume: 89
Issue: 2
Pages: 320-8
•
•
•
•
•
Publication
32555258 | J:296665
First Author: Bidaud I
Year: 2020
Journal: Sci Rep
Title: Inhibition of G protein-gated K+ channels by tertiapin-Q rescues sinus node dysfunction and atrioventricular conduction in mouse models of primary bradycardia.
Volume: 10
Issue: 1
Pages: 9835
•
•
•
•
•
Publication
18662696 | J:139953
First Author: Bierhuizen MF
Year: 2008
Journal: J Mol Cell Cardiol
Title: In calcineurin-induced cardiac hypertrophy expression of Nav1.5, Cx40 and Cx43 is reduced by different mechanisms.
Volume: 45
Issue: 3
Pages: 373-84
•
•
•
•
•
Publication
24498049 | J:212685
First Author: Fontes MS
Year: 2014
Journal: PLoS One
Title: Changes in Cx43 and NaV1.5 expression precede the occurrence of substantial fibrosis in calcineurin-induced murine cardiac hypertrophy.
Volume: 9
Issue: 1
Pages: e87226
•
•
•
•
•
Publication
32713021 | J:299886
First Author: Saadeh K
Year: 2020
Journal: Ann N Y Acad Sci
Title: Protein expression profiles in murine ventricles modeling catecholaminergic polymorphic ventricular tachycardia: effects of genotype and sex.
Volume: 1478
Issue: 1
Pages: 63-74
•
•
•
•
•




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