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Search results 1 to 98 out of 98 for Sirt5

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Category: Publication
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Type Details Score
Publication
39673708 | J:361352
First Author: Zhang X
Year: 2024
Journal: Cell Rep
Title: Desuccinylation of TBK1 by SIRT5 regulates inflammatory response of macrophages in sepsis.
Volume: 43
Issue: 12
Pages: 115060
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Publication
22076378 | J:177830
First Author: Du J
Year: 2011
Journal: Science
Title: Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase.
Volume: 334
Issue: 6057
Pages: 806-9
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Publication
24076663 | J:205149
 
First Author: Yu J
Year: 2013
Journal: Sci Rep
Title: Metabolic characterization of a Sirt5 deficient mouse model.
Volume: 3
Pages: 2806
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Publication
36879797 | J:334984
First Author: Zhang R
Year: 2023
Journal: iScience
Title: Histone malonylation is regulated by SIRT5 and KAT2A.
Volume: 26
Issue: 3
Pages: 106193
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Publication
24315375 | J:205910
First Author: Rardin MJ
Year: 2013
Journal: Cell Metab
Title: SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks.
Volume: 18
Issue: 6
Pages: 920-33
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Publication
23085393 | J:191242
First Author: Nakamura Y
Year: 2012
Journal: FEBS Lett
Title: SIRT5 deacetylates and activates urate oxidase in liver mitochondria of mice.
Volume: 586
Issue: 23
Pages: 4076-81
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Publication
31010955 | J:277362
First Author: Shuai L
Year: 2019
Journal: Diabetes
Title: SIRT5 Regulates Brown Adipocyte Differentiation and Browning of Subcutaneous White Adipose Tissue.
Volume: 68
Issue: 7
Pages: 1449-1461
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Publication
27113762 | J:234492
First Author: Zhou L
Year: 2016
Journal: EMBO Rep
Title: SIRT5 promotes IDH2 desuccinylation and G6PD deglutarylation to enhance cellular antioxidant defense.
Volume: 17
Issue: 6
Pages: 811-22
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Publication
33479498 | J:303959
First Author: Abril YLN
Year: 2021
Journal: Oncogene
Title: Pharmacological and genetic perturbation establish SIRT5 as a promising target in breast cancer.
Volume: 40
Issue: 9
Pages: 1644-1658
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Publication
26073543 | J:226118
First Author: Nishida Y
Year: 2015
Journal: Mol Cell
Title: SIRT5 Regulates both Cytosolic and Mitochondrial Protein Malonylation with Glycolysis as a Major Target.
Volume: 59
Issue: 2
Pages: 321-32
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Publication
29491006 | J:261391
 
First Author: Chen XF
Year: 2018
Journal: EMBO Rep
Title: SIRT5 inhibits peroxisomal ACOX1 to prevent oxidative damage and is downregulated in liver cancer.
Volume: 19
Issue: 5
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Publication
30017194 | J:271428
First Author: Bentley NL
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Protein hypoacylation induced by Sirt5 overexpression has minimal metabolic effect in mice.
Volume: 503
Issue: 3
Pages: 1349-1355
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Publication
30471144 | J:321181
First Author: Moon H
Year: 2019
Journal: Exp Dermatol
Title: Sirt5 is dispensable for BrafV600E -mediated cutaneous melanoma development and growth in vivo.
Volume: 28
Issue: 1
Pages: 83-85
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Publication
38846003 | J:360357
First Author: Yuan T
Year: 2024
Journal: iScience
Title: Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice.
Volume: 27
Issue: 6
Pages: 109991
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Publication
19410549 | J:148769
First Author: Nakagawa T
Year: 2009
Journal: Cell
Title: SIRT5 Deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle.
Volume: 137
Issue: 3
Pages: 560-70
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Publication
30279144 | J:279147
 
First Author: Du Y
Year: 2018
Journal: EBioMedicine
Title: SIRT5 deacylates metabolism-related proteins and attenuates hepatic steatosis in ob/ob mice.
Volume: 36
Pages: 347-357
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Publication
29440987 | J:310553
 
First Author: Koronowski KB
Year: 2018
Journal: Front Neurosci
Title: Metabolomics Based Identification of SIRT5 and Protein Kinase C Epsilon Regulated Pathways in Brain.
Volume: 12
Pages: 32
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Publication
27051063 | J:232110
First Author: Sadhukhan S
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function.
Volume: 113
Issue: 16
Pages: 4320-5
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Publication
34245764 | J:312409
First Author: Hu T
Year: 2021
Journal: Gastroenterology
Title: Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression.
Volume: 161
Issue: 5
Pages: 1584-1600
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Publication
28614718 | J:254358
First Author: Wang F
Year: 2017
Journal: Cell Rep
Title: SIRT5 Desuccinylates and Activates Pyruvate Kinase M2 to Block Macrophage IL-1β Production and to Prevent DSS-Induced Colitis in Mice.
Volume: 19
Issue: 11
Pages: 2331-2344
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Publication
28458255 | J:246021
First Author: Zhang Y
Year: 2017
Journal: J Biol Chem
Title: Lysine desuccinylase SIRT5 binds to cardiolipin and regulates the electron transport chain.
Volume: 292
Issue: 24
Pages: 10239-10249
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Publication
35157847 | J:327488
First Author: Bhatt DP
Year: 2022
Journal: J Biol Chem
Title: Deglutarylation of glutaryl-CoA dehydrogenase by deacylating enzyme SIRT5 promotes lysine oxidation in mice.
Volume: 298
Issue: 4
Pages: 101723
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Publication
20097174 | J:158016
First Author: Ogura M
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Overexpression of SIRT5 confirms its involvement in deacetylation and activation of carbamoyl phosphate synthetase 1.
Volume: 393
Issue: 1
Pages: 73-8
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Publication
31632409 | J:284390
 
First Author: Heinonen T
Year: 2019
Journal: Front Immunol
Title: Impact of the Dual Deletion of the Mitochondrial Sirtuins SIRT3 and SIRT5 on Anti-microbial Host Defenses.
Volume: 10
Pages: 2341
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Publication
25541039 | J:223969
 
First Author: Liu L
Year: 2015
Journal: Behav Brain Res
Title: Protective role of SIRT5 against motor deficit and dopaminergic degeneration in MPTP-induced mice model of Parkinson's disease.
Volume: 281
Pages: 215-21
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Publication
27445698 | J:244413
 
First Author: Li F
Year: 2016
Journal: Front Cell Neurosci
Title: SIRT5 Deficiency Enhances Susceptibility to Kainate-Induced Seizures and Exacerbates Hippocampal Neurodegeneration not through Mitochondrial Antioxidant Enzyme SOD2.
Volume: 10
Pages: 171
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Publication
25811481 | J:232966
First Author: Zhang Y
Year: 2015
Journal: PLoS One
Title: SIRT3 and SIRT5 regulate the enzyme activity and cardiolipin binding of very long-chain acyl-CoA dehydrogenase.
Volume: 10
Issue: 3
Pages: e0122297
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Publication
24687991 | J:216530
First Author: Buler M
Year: 2014
Journal: FASEB J
Title: SIRT5 is under the control of PGC-1α and AMPK and is involved in regulation of mitochondrial energy metabolism.
Volume: 28
Issue: 7
Pages: 3225-37
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Publication
30846716 | J:275888
First Author: Lin JB
Year: 2019
Journal: Sci Rep
Title: Combined SIRT3 and SIRT5 deletion is associated with inner retinal dysfunction in a mouse model of type 1 diabetes.
Volume: 9
Issue: 1
Pages: 3799
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Publication
30849386 | J:295170
 
First Author: Nandi SK
Year: 2019
Journal: Exp Eye Res
Title: The absence of SIRT3 and SIRT5 promotes the acetylation of lens proteins and improves the chaperone activity of α-crystallin in mouse lenses.
Volume: 182
Pages: 1-9
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Publication
36653443 | J:340143
First Author: Mao J
Year: 2023
Journal: Exp Mol Med
Title: SIRT5-related desuccinylation modification of AIFM1 protects against compression-induced intervertebral disc degeneration by regulating mitochondrial homeostasis.
Volume: 55
Issue: 1
Pages: 253-268
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Publication
34966740 | J:316920
 
First Author: Duan Q
Year: 2021
Journal: Front Cell Dev Biol
Title: Sirtuin 5 is Dispensable for CD8+ T Cell Effector and Memory Differentiation.
Volume: 9
Pages: 761193
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Publication
30515162 | J:337315
 
First Author: Heinonen T
Year: 2018
Journal: Front Immunol
Title: Sirtuin 5 Deficiency Does Not Compromise Innate Immune Responses to Bacterial Infections.
Volume: 9
Pages: 2675
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Publication
23806337 | J:203468
First Author: Park J
Year: 2013
Journal: Mol Cell
Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.
Volume: 50
Issue: 6
Pages: 919-30
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Publication
18680753 | J:168967
First Author: Schlicker C
Year: 2008
Journal: J Mol Biol
Title: Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5.
Volume: 382
Issue: 3
Pages: 790-801
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Publication
28972174 | J:252043
First Author: Hershberger KA
Year: 2017
Journal: J Biol Chem
Title: Sirtuin 5 is required for mouse survival in response to cardiac pressure overload.
Volume: 292
Issue: 48
Pages: 19767-19781
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Publication
35851833 | J:344069
First Author: Guo AH
Year: 2022
Journal: Sci Rep
Title: Sirtuin 5 levels are limiting in preserving cardiac function and suppressing fibrosis in response to pressure overload.
Volume: 12
Issue: 1
Pages: 12258
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Publication
18054327 | J:130436
First Author: Nakamura Y
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Localization of mouse mitochondrial SIRT proteins: shift of SIRT3 to nucleus by co-expression with SIRT5.
Volume: 366
Issue: 1
Pages: 174-9
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Publication
31575700 | J:298412
First Author: Chiba T
Year: 2019
Journal: J Am Soc Nephrol
Title: Sirtuin 5 Regulates Proximal Tubule Fatty Acid Oxidation to Protect against AKI.
Volume: 30
Issue: 12
Pages: 2384-2398
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Publication
24703693 | J:213152
First Author: Tan M
Year: 2014
Journal: Cell Metab
Title: Lysine glutarylation is a protein posttranslational modification regulated by SIRT5.
Volume: 19
Issue: 4
Pages: 605-17
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Publication
31000437 | J:275689
First Author: Wang G
Year: 2019
Journal: Mol Cell
Title: Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation.
Volume: 74
Issue: 4
Pages: 844-857.e7
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Publication
30726738 | J:277712
First Author: Fisher-Wellman KH
Year: 2019
Journal: Cell Rep
Title: Respiratory Phenomics across Multiple Models of Protein Hyperacylation in Cardiac Mitochondria Reveals a Marginal Impact on Bioenergetics.
Volume: 26
Issue: 6
Pages: 1557-1572.e8
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Publication
35613279 | J:326799
First Author: Head PE
Year: 2022
Journal: Sci Transl Med
Title: Aberrant methylmalonylation underlies methylmalonic acidemia and is attenuated by an engineered sirtuin.
Volume: 14
Issue: 646
Pages: eabn4772
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Publication
27681422 | J:265592
First Author: Lin JB
Year: 2016
Journal: Cell Rep
Title: NAMPT-Mediated NAD(+) Biosynthesis Is Essential for Vision In Mice.
Volume: 17
Issue: 1
Pages: 69-85
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Publication
33110171 | J:298941
First Author: Goetzman ES
Year: 2020
Journal: Sci Rep
Title: Impaired mitochondrial medium-chain fatty acid oxidation drives periportal macrovesicular steatosis in sirtuin-5 knockout mice.
Volume: 10
Issue: 1
Pages: 18367
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Publication
29769314 | J:267100
First Author: Hershberger KA
Year: 2018
Journal: J Biol Chem
Title: Ablation of Sirtuin5 in the postnatal mouse heart results in protein succinylation and normal survival in response to chronic pressure overload.
Volume: 293
Issue: 27
Pages: 10630-10645
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Publication
39766215 | J:361337
 
First Author: Zhang Y
Year: 2024
Journal: Biomolecules
Title: Sirtuin-5 Is Recruited to Hepatic Peroxisomes in Mice Fed Dodecanedioic Acid but Has Little Impact on the Peroxisomal Succinylome.
Volume: 14
Issue: 12
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Publication
27435822 | J:337573
 
First Author: Morris-Blanco KC
Year: 2016
Journal: Sci Rep
Title: Protein Kinase C Epsilon Promotes Cerebral Ischemic Tolerance Via Modulation of Mitochondrial Sirt5.
Volume: 6
Pages: 29790
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Publication
38169591 | J:351144
First Author: Wei C
Year: 2024
Journal: Int J Biol Sci
Title: SIRT5-related lysine demalonylation of GSTP1 contributes to cardiomyocyte pyroptosis suppression in diabetic cardiomyopathy.
Volume: 20
Issue: 2
Pages: 585-605
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Publication
26388266 | J:251621
 
First Author: Boylston JA
Year: 2015
Journal: J Mol Cell Cardiol
Title: Characterization of the cardiac succinylome and its role in ischemia-reperfusion injury.
Volume: 88
Pages: 73-81
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Publication
34644302 | J:311741
First Author: Zhang Y
Year: 2021
Journal: PLoS One
Title: The enzyme activity of mitochondrial trifunctional protein is not altered by lysine acetylation or lysine succinylation.
Volume: 16
Issue: 10
Pages: e0256619
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Publication
21908771 | J:180637
First Author: Peng C
Year: 2011
Journal: Mol Cell Proteomics
Title: The first identification of lysine malonylation substrates and its regulatory enzyme.
Volume: 10
Issue: 12
Pages: M111.012658
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Publication
20506229 | J:165463
First Author: Scapoli L
Year: 2010
Journal: Hum Mutat
Title: Expression and association data strongly support JARID2 involvement in nonsyndromic cleft lip with or without cleft palate.
Volume: 31
Issue: 7
Pages: 794-800
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Publication
20644252 | J:163766
First Author: Kawamura Y
Year: 2010
Journal: J Clin Invest
Title: Sirt3 protects in vitro-fertilized mouse preimplantation embryos against oxidative stress-induced p53-mediated developmental arrest.
Volume: 120
Issue: 8
Pages: 2817-28
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17923681 | J:129009
First Author: Lombard DB
Year: 2007
Journal: Mol Cell Biol
Title: Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation.
Volume: 27
Issue: 24
Pages: 8807-14
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Publication
38288355 | J:344966
First Author: Wei Y
Year: 2024
Journal: iScience
Title: Sirt6 regulates the proliferation of neural precursor cells and cortical neurogenesis in mice.
Volume: 27
Issue: 2
Pages: 108706
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Publication
26767982 | J:233904
First Author: Martin J
Year: 2016
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Nutritional stress exacerbates hepatic steatosis induced by deletion of the histidine nucleotide-binding (Hint2) mitochondrial protein.
Volume: 310
Issue: 7
Pages: G497-509
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18824292 | J:147317
First Author: Witt O
Year: 2009
Journal: Cancer Lett
Title: HDAC family: What are the cancer relevant targets?
Volume: 277
Issue: 1
Pages: 8-21
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27166947 | J:235368
First Author: Gómez-Del Arco P
Year: 2016
Journal: Cell Metab
Title: The Chromatin Remodeling Complex Chd4/NuRD Controls Striated Muscle Identity and Metabolic Homeostasis.
Volume: 23
Issue: 5
Pages: 881-92
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- | J:342612
       
First Author: UniProt curators
Year: 2014
Title: Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features
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- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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18614015 | J:151002
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
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20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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