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Search results 1 to 100 out of 141 for Sos1

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Category: Publication
Type Details Score
Publication
First Author: You X
Year: 2018
Journal: Blood
Title: Unique dependence on Sos1 in Kras G12D -induced leukemogenesis.
Volume: 132
Issue: 24
Pages: 2575-2579
Publication  
First Author: Gómez C
Year: 2022
Journal: Cancers (Basel)
Title: Critical Requirement of SOS1 for Development of BCR/ABL-Driven Chronic Myelogenous Leukemia.
Volume: 14
Issue: 16
Publication
First Author: Kortum RL
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Targeted Sos1 deletion reveals its critical role in early T-cell development.
Volume: 108
Issue: 30
Pages: 12407-12
Publication
First Author: Baltanás FC
Year: 2023
Journal: Nat Commun
Title: Critical requirement of SOS1 for tumor development and microenvironment modulation in KRAS(G12D)-driven lung adenocarcinoma.
Volume: 14
Issue: 1
Pages: 5856
Publication
First Author: Qian X
Year: 2000
Journal: EMBO J
Title: The Sos1 and Sos2 Ras-specific exchange factors: differences in placental expression and signaling properties.
Volume: 19
Issue: 4
Pages: 642-54
Publication      
First Author: Liceras-Boillos P
Year: 2018
Journal: Mol Cell Biol
Title: DIFFERENTIAL ROLE OF THE RasGEFs SOS1 AND SOS2 IN MOUSE SKIN HOMEOSTASIS AND CARCINOGENESIS.
Publication
First Author: Baltanás FC
Year: 2013
Journal: Mol Cell Biol
Title: Functional redundancy of Sos1 and Sos2 for lymphopoiesis and organismal homeostasis and survival.
Volume: 33
Issue: 22
Pages: 4562-78
Publication
First Author: Chen PC
Year: 2010
Journal: J Clin Invest
Title: Activation of multiple signaling pathways causes developmental defects in mice with a Noonan syndrome–associated Sos1 mutation.
Volume: 120
Issue: 12
Pages: 4353-65
Publication
First Author: Chardin P
Year: 1994
Journal: Cytogenet Cell Genet
Title: Chromosomal localization of two genes encoding human ras exchange factors: SOS1 maps to the 2p22-->p16 region and SOS2 to the 14q21-->q22 region of the human genome.
Volume: 66
Issue: 1
Pages: 68-9
Publication
First Author: Nielsen KH
Year: 1997
Journal: Mol Cell Biol
Title: The Ras-specific exchange factors mouse Sos1 (mSos1) and mSos2 are regulated differently: mSos2 contains ubiquitination signals absent in mSos1.
Volume: 17
Issue: 12
Pages: 7132-8
Publication
First Author: Kortum RL
Year: 2013
Journal: Sci Signal
Title: The ability of Sos1 to oligomerize the adaptor protein LAT is separable from its guanine nucleotide exchange activity in vivo.
Volume: 6
Issue: 301
Pages: ra99
Publication
First Author: Wang DZ
Year: 1997
Journal: Genes Dev
Title: Mutation in Sos1 dominantly enhances a weak allele of the EGFR, demonstrating a requirement for Sos1 in EGFR signaling and development.
Volume: 11
Issue: 3
Pages: 309-20
Publication
First Author: Houtman JC
Year: 2006
Journal: Nat Struct Mol Biol
Title: Oligomerization of signaling complexes by the multipoint binding of GRB2 to both LAT and SOS1.
Volume: 13
Issue: 9
Pages: 798-805
Publication
First Author: Cheng AM
Year: 1998
Journal: Cell
Title: Mammalian Grb2 regulates multiple steps in embryonic development and malignant transformation.
Volume: 95
Issue: 6
Pages: 793-803
Publication
First Author: Kortum RL
Year: 2013
Journal: J Immunol
Title: A phospholipase C-γ1-independent, RasGRP1-ERK-dependent pathway drives lymphoproliferative disease in linker for activation of T cells-Y136F mutant mice.
Volume: 190
Issue: 1
Pages: 147-58
Publication
First Author: Findlay GM
Year: 2013
Journal: Cell
Title: Interaction domains of Sos1/Grb2 are finely tuned for cooperative control of embryonic stem cell fate.
Volume: 152
Issue: 5
Pages: 1008-20
Publication
First Author: Kortum RL
Year: 2012
Journal: Mol Cell Biol
Title: Deconstructing Ras signaling in the thymus.
Volume: 32
Issue: 14
Pages: 2748-59
Publication  
First Author: Jun JE
Year: 2019
Journal: Sci Signal
Title: Alternative ZAP70-p38 signals prime a classical p38 pathway through LAT and SOS to support regulatory T cell differentiation.
Volume: 12
Issue: 591
Publication
First Author: Cherniack AD
Year: 1995
Journal: J Biol Chem
Title: Disassembly of Son-of-sevenless proteins from Grb2 during p21ras desensitization by insulin.
Volume: 270
Issue: 4
Pages: 1485-8
Publication
First Author: Reynolds LF
Year: 2004
Journal: J Biol Chem
Title: Vav1 transduces T cell receptor signals to the activation of the Ras/ERK pathway via LAT, Sos, and RasGRP1.
Volume: 279
Issue: 18
Pages: 18239-46
Publication
First Author: Webb GC
Year: 1993
Journal: Genomics
Title: Mammalian homologues of the Drosophila Son of sevenless gene map to murine chromosomes 17 and 12 and to human chromosomes 2 and 14, respectively.
Volume: 18
Issue: 1
Pages: 14-9
Publication
First Author: Hall BE
Year: 2001
Journal: J Biol Chem
Title: Structure-based mutagenesis reveals distinct functions for Ras switch 1 and switch 2 in Sos-catalyzed guanine nucleotide exchange.
Volume: 276
Issue: 29
Pages: 27629-37
Publication
First Author: Ferguson MR
Year: 2004
Journal: Protein Sci
Title: Directed discovery of bivalent peptide ligands to an SH3 domain.
Volume: 13
Issue: 3
Pages: 626-32
Publication
First Author: Ferreon JC
Year: 2005
Journal: J Biol Chem
Title: Molecular determinants of TRIF proteolysis mediated by the hepatitis C virus NS3/4A protease.
Volume: 280
Issue: 21
Pages: 20483-92
Publication
First Author: Miura K
Year: 2001
Journal: J Biol Chem
Title: The Sos1-Rac1 signaling. Possible involvement of a vacuolar H(+)-ATPase E subunit.
Volume: 276
Issue: 49
Pages: 46276-83
Publication
First Author: Scita G
Year: 2001
Journal: J Cell Biol
Title: An effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin-polymerizing machine.
Volume: 154
Issue: 5
Pages: 1031-44
Publication
First Author: Bowtell D
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: Identification of murine homologues of the Drosophila son of sevenless gene: potential activators of ras.
Volume: 89
Issue: 14
Pages: 6511-5
Publication
First Author: Guittard G
Year: 2015
Journal: Eur J Immunol
Title: Absence of both Sos-1 and Sos-2 in peripheral CD4(+) T cells leads to PI3K pathway activation and defects in migration.
Volume: 45
Issue: 8
Pages: 2389-95
Publication
First Author: Jun HJ
Year: 2014
Journal: Endocrinology
Title: ROS1 signaling regulates epithelial differentiation in the epididymis.
Volume: 155
Issue: 9
Pages: 3661-73
Publication
First Author: Yulug IG
Year: 1993
Journal: Genomics
Title: A homologue of the Drosophila Son of sevenless gene maps to mouse chromosome 17.
Volume: 18
Issue: 3
Pages: 733-4
Publication
First Author: Kouhara H
Year: 1997
Journal: Cell
Title: A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway.
Volume: 89
Issue: 5
Pages: 693-702
Publication
First Author: Zhang J
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Identification of K-ras as the major regulator for cytokine-dependent Akt activation in erythroid progenitors in vivo.
Volume: 102
Issue: 41
Pages: 14605-10
Publication
First Author: Khalaf WF
Year: 2005
Journal: Blood
Title: K-Ras is essential for normal fetal liver erythropoiesis.
Volume: 105
Issue: 9
Pages: 3538-41
Publication
First Author: Zhang J
Year: 2007
Journal: Cell Cycle
Title: Endogenous K-ras signaling in erythroid differentiation.
Volume: 6
Issue: 16
Pages: 1970-3
Publication
First Author: Egan SE
Year: 1993
Journal: Nature
Title: Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation.
Volume: 363
Issue: 6424
Pages: 45-51
Publication
First Author: Wei X
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Kindlin-2 regulates renal tubular cell plasticity by activation of Ras and its downstream signaling.
Volume: 306
Issue: 2
Pages: F271-8
Publication
First Author: Hoeppner MA
Year: 1996
Journal: Nucleic Acids Res
Title: Cloning and characterization of mouse CCAAT binding factor.
Volume: 24
Issue: 6
Pages: 1091-8
Publication
First Author: Xu XX
Year: 1998
Journal: Oncogene
Title: Disabled-2 (Dab2) is an SH3 domain-binding partner of Grb2.
Volume: 16
Issue: 12
Pages: 1561-9
Publication
First Author: Sakaue M
Year: 1995
Journal: Mol Cell Biol
Title: A dominant-negative mutant of mSOS1 inhibits insulin-induced Ras activation and reveals Ras-dependent and -independent insulin signaling pathways.
Volume: 15
Issue: 1
Pages: 379-88
Publication
First Author: Kannan S
Year: 1997
Journal: J Biol Chem
Title: Cripto enhances the tyrosine phosphorylation of Shc and activates mitogen-activated protein kinase (MAPK) in mammary epithelial cells.
Volume: 272
Issue: 6
Pages: 3330-5
Publication
First Author: Spencer ML
Year: 2002
Journal: J Biol Chem
Title: Nerve growth factor-dependent activation of the small GTPase Rin.
Volume: 277
Issue: 20
Pages: 17605-15
Publication
First Author: den Hertog J
Year: 1994
Journal: EMBO J
Title: Phosphorylation of receptor protein-tyrosine phosphatase alpha on Tyr789, a binding site for the SH3-SH2-SH3 adaptor protein GRB-2 in vivo.
Volume: 13
Issue: 13
Pages: 3020-32
Publication
First Author: Zhang M
Year: 2005
Journal: J Immunol
Title: CD45 signals outside of lipid rafts to promote ERK activation, synaptic raft clustering, and IL-2 production.
Volume: 174
Issue: 3
Pages: 1479-90
Publication
First Author: Fishel R
Year: 1993
Journal: Cell
Title: The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer.
Volume: 75
Issue: 5
Pages: 1027-38
Publication
First Author: Yohannan J
Year: 1999
Journal: J Biol Chem
Title: Analysis of tyrosine phosphorylation-dependent interactions between stimulatory effector proteins and the B cell co-receptor CD22.
Volume: 274
Issue: 26
Pages: 18769-76
Publication
First Author: Kon-Kozlowski M
Year: 1996
Journal: J Biol Chem
Title: The tyrosine phosphatase PTP1C associates with Vav, Grb2, and mSos1 in hematopoietic cells.
Volume: 271
Issue: 7
Pages: 3856-62
Publication
First Author: Suire S
Year: 2019
Journal: J Leukoc Biol
Title: Frontline Science: TNF-α and GM-CSF1 priming augments the role of SOS1/2 in driving activation of Ras, PI3K-γ, and neutrophil proinflammatory responses.
Volume: 106
Issue: 4
Pages: 815-822
Publication  
First Author: Sala V
Year: 2012
Journal: Mol Med
Title: Signaling to cardiac hypertrophy: insights from human and mouse RASopathies.
Volume: 18
Pages: 938-47
Publication
First Author: Sasaoka T
Year: 1996
Journal: Endocrinology
Title: Comparison of the insulin and insulin-like growth factor 1 mitogenic intracellular signaling pathways.
Volume: 137
Issue: 10
Pages: 4427-34
Publication
First Author: Xie Y
Year: 2005
Journal: Mol Reprod Dev
Title: Six post-implantation lethal knockouts of genes for lipophilic MAPK pathway proteins are expressed in preimplantation mouse embryos and trophoblast stem cells.
Volume: 71
Issue: 1
Pages: 1-11
Publication
First Author: Gross I
Year: 2001
Journal: J Biol Chem
Title: Mammalian sprouty proteins inhibit cell growth and differentiation by preventing ras activation.
Volume: 276
Issue: 49
Pages: 46460-8
Publication
First Author: Rozakis-Adcock M
Year: 1993
Journal: Nature
Title: The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1.
Volume: 363
Issue: 6424
Pages: 83-5
Publication
First Author: Chook YM
Year: 1996
Journal: J Biol Chem
Title: The Grb2-mSos1 complex binds phosphopeptides with higher affinity than Grb2.
Volume: 271
Issue: 48
Pages: 30472-8
Publication
First Author: Mathew P
Year: 1995
Journal: Cytogenet Cell Genet
Title: Localization of the murine homolog of the anaplastic lymphoma kinase (AlK) gene on mouse chromosome 17.
Volume: 70
Issue: 1-2
Pages: 143-4
Publication
First Author: Salojin K
Year: 1997
Journal: J Exp Med
Title: Impaired plasma membrane targeting of Grb2-murine son of sevenless (mSOS) complex and differential activation of the Fyn-T cell receptor (TCR)-zeta-Cbl pathway mediate T cell hyporesponsiveness in autoimmune nonobese diabetic mice.
Volume: 186
Issue: 6
Pages: 887-97
Publication
First Author: Schmutte C
Year: 1998
Journal: Cancer Res
Title: Refined chromosomal localization of the mismatch repair and hereditary nonpolyposis colorectal cancer genes hMSH2 and hMSH6.
Volume: 58
Issue: 22
Pages: 5023-6
Publication
First Author: Oliver G
Year: 1995
Journal: Development
Title: Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development.
Volume: 121
Issue: 12
Pages: 4045-55
Publication
First Author: Goodearl A
Year: 2001
Journal: Dev Neurosci
Title: Neuregulin-induced association of Sos Ras exchange protein with HER2(erbB2)/HER3(erbB3) receptor complexes in Schwann cells through a specific Grb2-HER2(erbB2) interaction.
Volume: 23
Issue: 1
Pages: 25-30
Publication
First Author: Ozaki K
Year: 2005
Journal: J Cell Sci
Title: Efficient suppression of FGF-2-induced ERK activation by the cooperative interaction among mammalian Sprouty isoforms.
Volume: 118
Issue: Pt 24
Pages: 5861-71
Publication
First Author: Halupa A
Year: 2005
Journal: Exp Cell Res
Title: Erythropoietin receptor Y479 couples to ERK1/2 activation via recruitment of phospholipase Cgamma.
Volume: 309
Issue: 1
Pages: 1-11
Publication
First Author: Lesourne R
Year: 2012
Journal: J Immunol
Title: Interchangeability of Themis1 and Themis2 in thymocyte development reveals two related proteins with conserved molecular function.
Volume: 189
Issue: 3
Pages: 1154-61
Publication
First Author: Oliver G
Year: 1995
Journal: Development
Title: Homeobox genes and connective tissue patterning.
Volume: 121
Issue: 3
Pages: 693-705
Publication
First Author: Liao J
Year: 2021
Journal: Cell Rep
Title: Prenatal correction of IGF2 to rescue the growth phenotypes in mouse models of Beckwith-Wiedemann and Silver-Russell syndromes.
Volume: 34
Issue: 6
Pages: 108729
Publication
First Author: Aoki K
Year: 2005
Journal: Mol Biol Cell
Title: Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells.
Volume: 16
Issue: 5
Pages: 2207-17
Publication
First Author: Garratt AN
Year: 2000
Journal: J Cell Biol
Title: A dual role of erbB2 in myelination and in expansion of the schwann cell precursor pool.
Volume: 148
Issue: 5
Pages: 1035-46
Publication
First Author: Huang ZP
Year: 2010
Journal: Arterioscler Thromb Vasc Biol
Title: Loss of microRNAs in neural crest leads to cardiovascular syndromes resembling human congenital heart defects.
Volume: 30
Issue: 12
Pages: 2575-86
Publication
First Author: Brinkmann BG
Year: 2008
Journal: Neuron
Title: Neuregulin-1/ErbB signaling serves distinct functions in myelination of the peripheral and central nervous system.
Volume: 59
Issue: 4
Pages: 581-95
Publication
First Author: Gaikwad JS
Year: 2001
Journal: Gene
Title: Identification of tooth-specific downstream targets of Runx2.
Volume: 279
Issue: 1
Pages: 91-7
Publication
First Author: Wang Y
Year: 2004
Journal: Dev Dyn
Title: Entire mitogen activated protein kinase (MAPK) pathway is present in preimplantation mouse embryos.
Volume: 231
Issue: 1
Pages: 72-87
Publication      
First Author: Database for Exchangeable Gene Trap Clones
Year: 2006
Journal: Unpublished
Title: Information obtained from the Database for Exchangeable Gene Trap Clones (EGTC), an official database of the Gene Trap Project of the Institute of Molecular Embryology and Genetics and the Institute of Resource Development and Analysis, Kumamoto University, Japan
Publication
First Author: Bulfone A
Year: 2005
Journal: J Neurosci
Title: Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.
Volume: 25
Issue: 33
Pages: 7586-600
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center
Publication
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
Publication
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
Publication        
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).