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Search results 1 to 100 out of 271 for Tnni3

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Type Details Score
Publication
16936010 | J:119966
First Author: Bilchick KC
Year: 2007
Journal: Am J Physiol Heart Circ Physiol
Title: Heart failure-associated alterations in troponin I phosphorylation impair ventricular relaxation-afterload and force-frequency responses and systolic function.
Volume: 292
Issue: 1
Pages: H318-25
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37597489 | J:339970
 
First Author: Purdy AL
Year: 2023
Journal: J Mol Cell Cardiol
Title: Tnni3k influences cardiomyocyte S-phase activity and proliferation.
Volume: 183
Pages: 22-26
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Publication
37628941 | J:339644
 
First Author: Gu Q
Year: 2023
Journal: Int J Mol Sci
Title: Expression Levels of the Tnni3k Gene in the Heart Are Highly Associated with Cardiac and Glucose Metabolism-Related Phenotypes and Functional Pathways.
Volume: 24
Issue: 16
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Publication
19763165 | J:154116
First Author: Wheeler FC
Year: 2009
Journal: PLoS Genet
Title: Tnni3k modifies disease progression in murine models of cardiomyopathy.
Volume: 5
Issue: 9
Pages: e1000647
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Publication
8276817 | J:16384
First Author: Ausoni S
Year: 1994
Journal: J Biol Chem
Title: Structure and regulation of the mouse cardiac troponin I gene.
Volume: 269
Issue: 1
Pages: 339-46
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Publication
8195157 | J:31198
First Author: Guo X
Year: 1994
Journal: J Biol Chem
Title: Mutagenesis of cardiac troponin I. Role of the unique NH2-terminal peptide in myofilament activation.
Volume: 269
Issue: 21
Pages: 15210-6
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Publication
17540338 | J:122464
First Author: Opherk JP
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Cardiac-specific activation of Cre expression at late fetal development.
Volume: 359
Issue: 2
Pages: 209-13
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Publication
28066262 | J:243552
 
First Author: Liu X
Year: 2016
Journal: Front Physiol
Title: Restrictive Cardiomyopathy Caused by Troponin Mutations: Application of Disease Animal Models in Translational Studies.
Volume: 7
Pages: 629
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Publication
17526646 | J:126155
First Author: Liu J
Year: 2007
Journal: Am J Physiol Heart Circ Physiol
Title: Progressive troponin I loss impairs cardiac relaxation and causes heart failure in mice.
Volume: 293
Issue: 2
Pages: H1273-81
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Publication
29669813 | J:264134
First Author: Martin-Garrido A
Year: 2018
Journal: J Biol Chem
Title: Monophosphorylation of cardiac troponin-I at Ser-23/24 is sufficient to regulate cardiac myofibrillar Ca2+ sensitivity and calpain-induced proteolysis.
Volume: 293
Issue: 22
Pages: 8588-8599
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Publication
12923217 | J:133812
First Author: Pi Y
Year: 2003
Journal: J Physiol
Title: Protein kinase C and A sites on troponin I regulate myofilament Ca2+ sensitivity and ATPase activity in the mouse myocardium.
Volume: 552
Issue: Pt 3
Pages: 845-57
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Publication
19433057 | J:151170
First Author: Feng HZ
Year: 2009
Journal: Arch Biochem Biophys
Title: Myofilament incorporation determines the stoichiometry of troponin I in transgenic expression and the rescue of a null mutation.
Volume: 487
Issue: 1
Pages: 36-41
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Publication
11934831 | J:109759
First Author: Pi Y
Year: 2002
Journal: Circ Res
Title: Phosphorylation of troponin I controls cardiac twitch dynamics: evidence from phosphorylation site mutants expressed on a troponin I-null background in mice.
Volume: 90
Issue: 6
Pages: 649-56
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Publication
23810866 | J:308153
 
First Author: Li Y
Year: 2013
Journal: J Mol Cell Cardiol
Title: Dose-dependent diastolic dysfunction and early death in a mouse model with cardiac troponin mutations.
Volume: 62
Pages: 227-36
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Publication
16950368 | J:114537
First Author: Tsoutsman T
Year: 2006
Journal: J Mol Cell Cardiol
Title: Molecular insights from a novel cardiac troponin I mouse model of familial hypertrophic cardiomyopathy.
Volume: 41
Issue: 4
Pages: 623-32
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Publication
23352598 | J:206706
First Author: McKee LA
Year: 2013
Journal: Arch Biochem Biophys
Title: Sexually dimorphic myofilament function and cardiac troponin I phosphospecies distribution in hypertrophic cardiomyopathy mice.
Volume: 535
Issue: 1
Pages: 39-48
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Publication
22086914 | J:180606
First Author: Wang Y
Year: 2012
Journal: J Biol Chem
Title: Generation and functional characterization of knock-in mice harboring the cardiac troponin I-R21C mutation associated with hypertrophic cardiomyopathy.
Volume: 287
Issue: 3
Pages: 2156-67
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Publication
24973218 | J:307879
First Author: Dweck D
Year: 2014
Journal: J Biol Chem
Title: Long term ablation of protein kinase A (PKA)-mediated cardiac troponin I phosphorylation leads to excitation-contraction uncoupling and diastolic dysfunction in a knock-in mouse model of hypertrophic cardiomyopathy.
Volume: 289
Issue: 33
Pages: 23097-23111
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Publication
25961037 | J:307877
 
First Author: Liang J
Year: 2015
Journal: Biomed Res Int
Title: The R21C Mutation in Cardiac Troponin I Imposes Differences in Contractile Force Generation between the Left and Right Ventricles of Knock-In Mice.
Volume: 2015
Pages: 742536
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Publication
22940544 | J:198401
First Author: Henze M
Year: 2013
Journal: Biochim Biophys Acta
Title: New insights into the functional significance of the acidic region of the unique N-terminal extension of cardiac troponin I.
Volume: 1833
Issue: 4
Pages: 823-32
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Publication
18096573 | J:161911
First Author: Iorga B
Year: 2008
Journal: Cardiovasc Res
Title: Lys184 deletion in troponin I impairs relaxation kinetics and induces hypercontractility in murine cardiac myofibrils.
Volume: 77
Issue: 4
Pages: 676-86
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Publication
10642551 | J:59433
First Author: Murphy AM
Year: 2000
Journal: Science
Title: Transgenic mouse model of stunned myocardium.
Volume: 287
Issue: 5452
Pages: 488-91
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11356618 | J:69919
First Author: Kögler H
Year: 2001
Journal: Am J Physiol Heart Circ Physiol
Title: Maintained contractile reserve in a transgenic mouse model of myocardial stunning.
Volume: 280
Issue: 6
Pages: H2623-30
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Publication
22683325 | J:186721
First Author: Davis J
Year: 2012
Journal: J Mol Cell Cardiol
Title: Diastolic dysfunction and thin filament dysregulation resulting from excitation-contraction uncoupling in a mouse model of restrictive cardiomyopathy.
Volume: 53
Issue: 3
Pages: 446-57
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Publication
11158984 | J:68042
First Author: MacGowan GA
Year: 2001
Journal: Am J Physiol Heart Circ Physiol
Title: Ischemic dysfunction in transgenic mice expressing troponin I lacking protein kinase C phosphorylation sites.
Volume: 280
Issue: 2
Pages: H835-43
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15611140 | J:97072
First Author: Barbato JC
Year: 2005
Journal: J Biol Chem
Title: Proteolytic N-terminal truncation of cardiac troponin I enhances ventricular diastolic function.
Volume: 280
Issue: 8
Pages: 6602-9
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Publication
8662015 | J:34377
First Author: Hastings KE
Year: 1996
Journal: J Mol Evol
Title: Strong evolutionary conservation of broadly expressed protein isoforms in the troponin I gene family and other vertebrate gene families.
Volume: 42
Issue: 6
Pages: 631-40
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8661099 | J:33933
First Author: Bhavsar PK
Year: 1996
Journal: Genomics
Title: Isolation and characterization of the human cardiac troponin I gene (TNNI3).
Volume: 35
Issue: 1
Pages: 11-23
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9464252 | J:45503
First Author: Jin JP
Year: 1998
Journal: Biochem Biophys Res Commun
Title: Developmentally regulated muscle type-specific alternative splicing of the COOH-terminal variable region of fast skeletal muscle troponin T and an aberrant splicing pathway to encode a mutant COOH-terminus.
Volume: 242
Issue: 3
Pages: 540-4
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16024565 | J:104781
First Author: Arteaga GM
Year: 2005
Journal: Am J Physiol Heart Circ Physiol
Title: Specific enhancement of sarcomeric response to Ca2+ protects murine myocardium against ischemia-reperfusion dysfunction.
Volume: 289
Issue: 5
Pages: H2183-92
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9241277 | J:113668
First Author: Kimura A
Year: 1997
Journal: Nat Genet
Title: Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy.
Volume: 16
Issue: 4
Pages: 379-82
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12809519 | J:113932
First Author: Li Q
Year: 2003
Journal: Biochemistry
Title: Troponin I binds polycystin-L and inhibits its calcium-induced channel activation.
Volume: 42
Issue: 24
Pages: 7618-25
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Publication
12562915 | J:133820
First Author: Konhilas JP
Year: 2003
Journal: J Physiol
Title: Troponin I in the murine myocardium: influence on length-dependent activation and interfilament spacing.
Volume: 547
Issue: Pt 3
Pages: 951-61
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Publication
17615373 | J:140293
First Author: Yasuda S
Year: 2007
Journal: Circ Res
Title: Cardiac transgenic and gene transfer strategies converge to support an important role for troponin I in regulating relaxation in cardiac myocytes.
Volume: 101
Issue: 4
Pages: 377-86
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Publication
19637843 | J:154873
First Author: Ayaz-Guner S
Year: 2009
Journal: Biochemistry
Title: In vivo phosphorylation site mapping in mouse cardiac troponin I by high resolution top-down electron capture dissociation mass spectrometry: Ser22/23 are the only sites basally phosphorylated.
Volume: 48
Issue: 34
Pages: 8161-70
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Publication
21777381 | J:193010
First Author: Zhang Z
Year: 2011
Journal: FEBS J
Title: Calcium-regulated conformational change in the C-terminal end segment of troponin I and its binding to tropomyosin.
Volume: 278
Issue: 18
Pages: 3348-59
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Publication
24326031 | J:227880
 
First Author: Akhter S
Year: 2014
Journal: Arch Biochem Biophys
Title: Restrictive cardiomyopathy mutations demonstrate functions of the C-terminal end-segment of troponin I.
Volume: 552-553
Pages: 3-10
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15507454 | J:308286
First Author: Sakthivel S
Year: 2005
Journal: J Biol Chem
Title: In vivo and in vitro analysis of cardiac troponin I phosphorylation.
Volume: 280
Issue: 1
Pages: 703-14
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12181153 | J:311979
First Author: Pyle WG
Year: 2002
Journal: Am J Physiol Heart Circ Physiol
Title: Troponin I serines 43/45 and regulation of cardiac myofilament function.
Volume: 283
Issue: 3
Pages: H1215-24
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Publication
30321814 | J:267512
 
First Author: Murata K
Year: 2018
Journal: iScience
Title: PRMT1 Deficiency in Mouse Juvenile Heart Induces Dilated Cardiomyopathy and Reveals Cryptic Alternative Splicing Products.
Volume: 8
Pages: 200-213
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Publication
14595408 | J:86800
First Author: Okazaki T
Year: 2003
Journal: Nat Med
Title: Autoantibodies against cardiac troponin I are responsible for dilated cardiomyopathy in PD-1-deficient mice.
Volume: 9
Issue: 12
Pages: 1477-83
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9915769 | J:53628
First Author: Huang X
Year: 1999
Journal: Circ Res
Title: Cardiac troponin I gene knockout: a mouse model of myocardial troponin I deficiency.
Volume: 84
Issue: 1
Pages: 1-8
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19797054 | J:156322
First Author: Feng HZ
Year: 2009
Journal: J Biol Chem
Title: Deletion of a genomic segment containing the cardiac troponin I gene knocks down expression of the slow troponin T gene and impairs fatigue tolerance of diaphragm muscle.
Volume: 284
Issue: 46
Pages: 31798-806
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17641226 | J:140289
First Author: Stelzer JE
Year: 2007
Journal: Circ Res
Title: Differential roles of cardiac myosin-binding protein C and cardiac troponin I in the myofibrillar force responses to protein kinase A phosphorylation.
Volume: 101
Issue: 5
Pages: 503-11
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Publication
24898585 | J:221709
First Author: Wei H
Year: 2014
Journal: Am J Physiol Cell Physiol
Title: A dominantly negative mutation in cardiac troponin I at the interface with troponin T causes early remodeling in ventricular cardiomyocytes.
Volume: 307
Issue: 4
Pages: C338-48
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25518962 | J:223982
First Author: Wei H
Year: 2015
Journal: Am J Physiol Cell Physiol
Title: NH2-terminal truncations of cardiac troponin I and cardiac troponin T produce distinct effects on contractility and calcium homeostasis in adult cardiomyocytes.
Volume: 308
Issue: 5
Pages: C397-404
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Publication
20551314 | J:166190
First Author: Wei B
Year: 2010
Journal: J Biol Chem
Title: Mutual rescues between two dominant negative mutations in cardiac troponin I and cardiac troponin T.
Volume: 285
Issue: 36
Pages: 27806-16
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19955219 | J:176112
First Author: van Amerongen MJ
Year: 2010
Journal: Cardiovasc Res
Title: E2F4 is required for cardiomyocyte proliferation.
Volume: 86
Issue: 1
Pages: 92-102
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23539503 | J:211438
First Author: Memo M
Year: 2013
Journal: Cardiovasc Res
Title: Familial dilated cardiomyopathy mutations uncouple troponin I phosphorylation from changes in myofibrillar Ca²⁺ sensitivity.
Volume: 99
Issue: 1
Pages: 65-73
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10878607 | J:63319
First Author: Millino C
Year: 2000
Journal: Dev Dyn
Title: Cardiac and smooth muscle cell contribution to the formation of the murine pulmonary veins.
Volume: 218
Issue: 3
Pages: 414-25
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22815472 | J:190407
First Author: Hyde AS
Year: 2012
Journal: J Biol Chem
Title: UDP-glucose dehydrogenase polymorphisms from patients with congenital heart valve defects disrupt enzyme stability and quaternary assembly.
Volume: 287
Issue: 39
Pages: 32708-16
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23748972 | J:201083
First Author: Mamidi R
Year: 2013
Journal: FASEB J
Title: Interplay between the overlapping ends of tropomyosin and the N terminus of cardiac troponin T affects tropomyosin states on actin.
Volume: 27
Issue: 9
Pages: 3848-59
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23176202 | J:211543
First Author: Kracklauer MP
Year: 2013
Journal: FEBS J
Title: Discontinuous thoracic venous cardiomyocytes and heart exhibit synchronized developmental switch of troponin isoforms.
Volume: 280
Issue: 3
Pages: 880-91
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17010989 | J:117012
First Author: Wang H
Year: 2006
Journal: J Mol Cell Cardiol
Title: PKC-betaII sensitizes cardiac myofilaments to Ca2+ by phosphorylating troponin I on threonine-144.
Volume: 41
Issue: 5
Pages: 823-33
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Publication
18815135 | J:143376
First Author: Feng HZ
Year: 2008
Journal: J Biol Chem
Title: Removal of the N-terminal extension of cardiac troponin I as a functional compensation for impaired myocardial beta-adrenergic signaling.
Volume: 283
Issue: 48
Pages: 33384-93
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Publication
28592524 | J:244438
     
First Author: Kruszka P
Year: 2017
Journal: J Med Genet
Title: Loss of function in ROBO1 is associated with tetralogy of Fallot and septal defects.
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29403069 | J:263013
First Author: Li Y
Year: 2018
Journal: Sci Rep
Title: Genetic targeting of Purkinje fibres by Sema3a-CreERT2.
Volume: 8
Issue: 1
Pages: 2382
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23734001 | J:218651
First Author: Sah R
Year: 2013
Journal: Circulation
Title: Timing of myocardial trpm7 deletion during cardiogenesis variably disrupts adult ventricular function, conduction, and repolarization.
Volume: 128
Issue: 2
Pages: 101-14
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30250288 | J:279166
First Author: He L
Year: 2018
Journal: Nat Protoc
Title: Genetic lineage tracing of resident stem cells by DeaLT.
Volume: 13
Issue: 10
Pages: 2217-2246
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31273086 | J:278239
 
First Author: Han X
Year: 2019
Journal: Development
Title: The lncRNA Hand2os1/Uph locus orchestrates heart development through regulation of precise expression of Hand2.
Volume: 146
Issue: 13
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18408133 | J:136827
First Author: Du J
Year: 2008
Journal: Am J Physiol Heart Circ Physiol
Title: Impaired relaxation is the main manifestation in transgenic mice expressing a restrictive cardiomyopathy mutation, R193H, in cardiac TnI.
Volume: 294
Issue: 6
Pages: H2604-13
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15863459 | J:104770
First Author: Duncan JG
Year: 2005
Journal: Am J Physiol Heart Circ Physiol
Title: Chronic xanthine oxidase inhibition prevents myofibrillar protein oxidation and preserves cardiac function in a transgenic mouse model of cardiomyopathy.
Volume: 289
Issue: 4
Pages: H1512-8
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Publication
35461809 | J:338961
First Author: Wang H
Year: 2022
Journal: J Biol Chem
Title: Dual Cre and Dre recombinases mediate synchronized lineage tracing and cell subset ablation in vivo.
Volume: 298
Issue: 6
Pages: 101965
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12551921 | J:82583
First Author: Burkart EM
Year: 2003
Journal: J Biol Chem
Title: Phosphorylation or glutamic acid substitution at protein kinase C sites on cardiac troponin I differentially depress myofilament tension and shortening velocity.
Volume: 278
Issue: 13
Pages: 11265-72
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Publication
7781893 | J:26132
First Author: Zhu L
Year: 1995
Journal: Dev Biol
Title: Developmental regulation of troponin I isoform genes in striated muscles of transgenic mice.
Volume: 169
Issue: 2
Pages: 487-503
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8825654 | J:30586
First Author: Bermingham N
Year: 1995
Journal: Genomics
Title: Mapping TNNC1, the gene that encodes cardiac troponin I in the human and the mouse.
Volume: 30
Issue: 3
Pages: 620-2
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9405409 | J:44737
First Author: MacLean DW
Year: 1997
Journal: J Biol Chem
Title: Tissue-specific alternative splicing of ascidian troponin I isoforms. Redesign of a protein isoform-generating mechanism during chordate evolution.
Volume: 272
Issue: 51
Pages: 32115-20
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14726296 | J:95785
First Author: Roman BB
Year: 2004
Journal: Am J Physiol Heart Circ Physiol
Title: Inhibition of PKC phosphorylation of cTnI improves cardiac performance in vivo.
Volume: 286
Issue: 6
Pages: H2089-95
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Publication
15249182 | J:132563
First Author: MacGowan GA
Year: 2004
Journal: Cardiovasc Res
Title: Troponin I protein kinase C phosphorylation sites and ventricular function.
Volume: 63
Issue: 2
Pages: 245-55
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19013134 | J:142223
First Author: Nan C
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Transcription factor Yin Yang 1 represses fetal troponin I gene expression in neonatal myocardial cells.
Volume: 378
Issue: 1
Pages: 62-7
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15601779 | J:95322
First Author: Kedar V
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin I.
Volume: 101
Issue: 52
Pages: 18135-40
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10594179 | J:58719
First Author: Huang QQ
Year: 1999
Journal: J Mol Evol
Title: Preserved close linkage between the genes encoding troponin I and troponin T, reflecting an evolution of adapter proteins coupling the Ca(2+) signaling of contractility.
Volume: 49
Issue: 6
Pages: 780-8
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20225205 | J:173512
First Author: Boogerd CJ
Year: 2010
Journal: Anat Rec (Hoboken)
Title: Expression of muscle segment homeobox genes in the developing myocardium.
Volume: 293
Issue: 6
Pages: 998-1001
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18612386 | J:137964
First Author: Ahmad F
Year: 2008
Journal: PLoS One
Title: The role of cardiac troponin T quantity and function in cardiac development and dilated cardiomyopathy.
Volume: 3
Issue: 7
Pages: e2642
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18362229 | J:153302
First Author: Tsoutsman T
Year: 2008
Journal: Circulation
Title: Severe heart failure and early mortality in a double-mutation mouse model of familial hypertrophic cardiomyopathy.
Volume: 117
Issue: 14
Pages: 1820-31
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Publication
20018870 | J:159755
First Author: Bardswell SC
Year: 2010
Journal: J Biol Chem
Title: Distinct sarcomeric substrates are responsible for protein kinase D-mediated regulation of cardiac myofilament Ca2+ sensitivity and cross-bridge cycling.
Volume: 285
Issue: 8
Pages: 5674-82
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Publication
23872634 | J:280846
First Author: Bezzina CR
Year: 2013
Journal: Nat Genet
Title: Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death.
Volume: 45
Issue: 9
Pages: 1044-9
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18671960 | J:141967
First Author: Nishii K
Year: 2008
Journal: Dev Biol
Title: Targeted disruption of the cardiac troponin T gene causes sarcomere disassembly and defects in heartbeat within the early mouse embryo.
Volume: 322
Issue: 1
Pages: 65-73
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Publication
36004502 | J:344097
First Author: Zhao J
Year: 2024
Journal: Dev Dyn
Title: Maternal and zygotic ZFP57 regulate coronary vascular formation and myocardium maturation in mouse embryo.
Volume: 253
Issue: 1
Pages: 144-156
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Publication
31954841 | J:360506
First Author: Oda T
Year: 2020
Journal: J Struct Biol
Title: Cryo-EM structures of cardiac thin filaments reveal the 3D architecture of troponin.
Volume: 209
Issue: 3
Pages: 107450
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19586048 | J:154887
First Author: Sumandea MP
Year: 2009
Journal: Biochemistry
Title: Impact of cardiac troponin T N-terminal deletion and phosphorylation on myofilament function.
Volume: 48
Issue: 32
Pages: 7722-31
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Publication
22966157 | J:203024
First Author: Ford SJ
Year: 2012
Journal: J Physiol
Title: The effects of slow skeletal troponin I expression in the murine myocardium are influenced by development-related shifts in myosin heavy chain isoform.
Volume: 590
Issue: 23
Pages: 6047-63
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Publication
28211472 | J:244024
 
First Author: Fukuda R
Year: 2017
Journal: Nat Commun
Title: Proteolysis regulates cardiomyocyte maturation and tissue integration.
Volume: 8
Pages: 14495
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Publication
19369973 | J:147421
First Author: Christoffels VM
Year: 2009
Journal: Nature
Title: Tbx18 and the fate of epicardial progenitors.
Volume: 458
Issue: 7240
Pages: E8-9; discussion E9-10
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Publication
16164837 | J:106344
First Author: Matalon R
Year: 2005
Journal: Int J Immunopathol Pharmacol
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