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Search results 1 to 100 out of 222 for Tph2

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Category: Publication
Type Details Score
Publication  
First Author: Liu H
Year: 2021
Journal: Endocrinology
Title: TPH2 in the Dorsal Raphe Nuclei Regulates Energy Balance in a Sex-Dependent Manner.
Volume: 162
Issue: 1
Publication
First Author: Gutknecht L
Year: 2008
Journal: J Neural Transm (Vienna)
Title: Deficiency of brain 5-HT synthesis but serotonergic neuron formation in Tph2 knockout mice.
Volume: 115
Issue: 8
Pages: 1127-32
Publication
First Author: Kulikov AV
Year: 2005
Journal: Genes Brain Behav
Title: Association between Tph2 gene polymorphism, brain tryptophan hydroxylase activity and aggressiveness in mouse strains.
Volume: 4
Issue: 8
Pages: 482-5
Publication
First Author: Gutknecht L
Year: 2012
Journal: PLoS One
Title: Impacts of brain serotonin deficiency following Tph2 inactivation on development and raphe neuron serotonergic specification.
Volume: 7
Issue: 8
Pages: e43157
Publication  
First Author: Mosienko V
Year: 2014
Journal: Neuropharmacology
Title: Adaptive changes in serotonin metabolism preserve normal behavior in mice with reduced TPH2 activity.
Volume: 85
Pages: 73-80
Publication
First Author: Carli M
Year: 2015
Journal: J Neurochem
Title: Tph2 gene deletion enhances amphetamine-induced hypermotility: effect of 5-HT restoration and role of striatal noradrenaline release.
Volume: 135
Issue: 4
Pages: 674-85
Publication
First Author: Pelosi B
Year: 2015
Journal: PLoS One
Title: Generation of a Tph2 Conditional Knockout Mouse Line for Time- and Tissue-Specific Depletion of Brain Serotonin.
Volume: 10
Issue: 8
Pages: e0136422
Publication
First Author: Gutknecht L
Year: 2015
Journal: Psychopharmacology (Berl)
Title: Interaction of brain 5-HT synthesis deficiency, chronic stress and sex differentially impact emotional behavior in Tph2 knockout mice.
Volume: 232
Issue: 14
Pages: 2429-41
Publication
First Author: Gutknecht L
Year: 2009
Journal: Eur Neuropsychopharmacol
Title: Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: convergent data from Tph2 knockout mice.
Volume: 19
Issue: 4
Pages: 266-82
Publication
First Author: Kriegebaum C
Year: 2010
Journal: Neurochem Int
Title: Brain-specific conditional and time-specific inducible Tph2 knockout mice possess normal serotonergic gene expression in the absence of serotonin during adult life.
Volume: 57
Issue: 5
Pages: 512-7
Publication  
First Author: Gorlova A
Year: 2020
Journal: J Affect Disord
Title: Stress-induced aggression in heterozygous TPH2 mutant mice is associated with alterations in serotonin turnover and expression of 5-HT6 and AMPA subunit 2A receptors.
Volume: 272
Pages: 440-451
Publication
First Author: Waider J
Year: 2013
Journal: Histochem Cell Biol
Title: GABA concentration and GABAergic neuron populations in limbic areas are differentially altered by brain serotonin deficiency in Tph2 knockout mice.
Volume: 139
Issue: 2
Pages: 267-81
Publication      
First Author: Gloss B
Year: 2011
Journal: MGI Direct Data Submission
Title: Generation of an inducible Tph2 cre transgene
Publication
First Author: Zhang X
Year: 2004
Journal: Science
Title: Tryptophan hydroxylase-2 controls brain serotonin synthesis.
Volume: 305
Issue: 5681
Pages: 217
Publication
First Author: Tenner K
Year: 2008
Journal: Neurosci Lett
Title: The mTPH2 C1473G single nucleotide polymorphism is not responsible for behavioural differences between mouse strains.
Volume: 431
Issue: 1
Pages: 21-5
Publication  
First Author: Mosienko V
Year: 2015
Journal: Behav Brain Res
Title: Life without brain serotonin: reevaluation of serotonin function with mice deficient in brain serotonin synthesis.
Volume: 277
Pages: 78-88
Publication  
First Author: Waider J
Year: 2019
Journal: Front Neurosci
Title: Serotonin Deficiency Increases Context-Dependent Fear Learning Through Modulation of Hippocampal Activity.
Volume: 13
Pages: 245
Publication
First Author: Siesser WB
Year: 2010
Journal: Neurosci Lett
Title: Tryptophan hydroxylase 2 genotype determines brain serotonin synthesis but not tissue content in C57Bl/6 and BALB/c congenic mice.
Volume: 481
Issue: 1
Pages: 6-11
Publication
First Author: Koshimizu H
Year: 2019
Journal: Neuropsychopharmacol Rep
Title: Comprehensive behavioral analysis and quantification of brain free amino acids of C57BL/6J congenic mice carrying the 1473G allele in tryptophan hydroxylase-2.
Volume: 39
Issue: 1
Pages: 56-60
Publication  
First Author: Bazovkina DV
Year: 2015
Journal: Neurosci Lett
Title: The C1473G polymorphism in the Tryptophan hydroxylase-2 gene: involvement in ethanol-related behavior in mice.
Volume: 589
Pages: 79-82
Publication
First Author: von Linstow CU
Year: 2022
Journal: J Alzheimers Dis
Title: The Combined Effects of Amyloidosis and Serotonin Deficiency by Tryptophan Hydroxylase-2 Knockout Impacts Viability of the APP/PS1 Mouse Model of Alzheimer's Disease.
Volume: 85
Issue: 3
Pages: 1283-1300
Publication
First Author: Montalbano A
Year: 2015
Journal: Eur Neuropsychopharmacol
Title: Cellular resilience: 5-HT neurons in Tph2(-/-) mice retain normal firing behavior despite the lack of brain 5-HT.
Volume: 25
Issue: 11
Pages: 2022-35
Publication  
First Author: Lemay F
Year: 2015
Journal: Neurosci Lett
Title: Increased ethanol consumption despite taste aversion in mice with a human tryptophan hydroxylase 2 loss of function mutation.
Volume: 609
Pages: 194-7
Publication  
First Author: Jørgensen CV
Year: 2013
Journal: Neurosci Lett
Title: Cerebral 5-HT2A receptor binding, but not mGluR2, is increased in tryptophan hydroxylase 2 decrease-of-function mice.
Volume: 555
Pages: 118-22
Publication
First Author: Omenetti A
Year: 2011
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Paracrine modulation of cholangiocyte serotonin synthesis orchestrates biliary remodeling in adults.
Volume: 300
Issue: 2
Pages: G303-15
Publication
First Author: Aboagye B
Year: 2021
Journal: Sci Rep
Title: Serotonin deficiency induced after brain maturation rescues consequences of early life adversity.
Volume: 11
Issue: 1
Pages: 5368
Publication  
First Author: Lieb MW
Year: 2019
Journal: Behav Brain Res
Title: Effects of maternal separation on serotonergic systems in the dorsal and median raphe nuclei of adult male Tph2-deficient mice.
Volume: 373
Pages: 112086
Publication
First Author: Kästner N
Year: 2019
Journal: Sci Rep
Title: Brain serotonin deficiency affects female aggression.
Volume: 9
Issue: 1
Pages: 1366
Publication
First Author: Waider J
Year: 2017
Journal: Transl Psychiatry
Title: Genetically driven brain serotonin deficiency facilitates panic-like escape behavior in mice.
Volume: 7
Issue: 10
Pages: e1246
Publication
First Author: Maddaloni G
Year: 2018
Journal: Sci Rep
Title: Serotonin depletion causes valproate-responsive manic-like condition and increased hippocampal neuroplasticity that are reversed by stress.
Volume: 8
Issue: 1
Pages: 11847
Publication
First Author: Pho H
Year: 2022
Journal: Physiol Rep
Title: The effect of brain serotonin deficiency on breathing is magnified by age.
Volume: 10
Issue: 10
Pages: e15245
Publication
First Author: Angoa-Pérez M
Year: 2012
Journal: J Neurochem
Title: Genetic depletion of brain 5HT reveals a common molecular pathway mediating compulsivity and impulsivity.
Volume: 121
Issue: 6
Pages: 974-84
Publication
First Author: Sakowski SA
Year: 2006
Journal: J Neurochem
Title: Mouse tryptophan hydroxylase isoform 2 and the role of proline 447 in enzyme function.
Volume: 96
Issue: 3
Pages: 758-65
Publication
First Author: Kulikov AV
Year: 2012
Journal: Behav Brain Res
Title: A pharmacological evidence of positive association between mouse intermale aggression and brain serotonin metabolism.
Volume: 233
Issue: 1
Pages: 113-9
Publication  
First Author: Bazhenova EY
Year: 2017
Journal: Neurosci Lett
Title: C1473G polymorphism in mouse tryptophan hydroxylase-2 gene in the regulation of the reaction to emotional stress.
Volume: 640
Pages: 105-110
Publication
First Author: Liu Y
Year: 2011
Journal: Nature
Title: Molecular regulation of sexual preference revealed by genetic studies of 5-HT in the brains of male mice.
Volume: 472
Issue: 7341
Pages: 95-9
Publication  
First Author: Takahashi A
Year: 2014
Journal: Front Neurosci
Title: Genetic mapping of escalated aggression in wild-derived mouse strain MSM/Ms: association with serotonin-related genes.
Volume: 8
Pages: 156
Publication  
First Author: Wong P
Year: 2015
Journal: Front Behav Neurosci
Title: Early life environmental and pharmacological stressors result in persistent dysregulations of the serotonergic system.
Volume: 9
Pages: 94
Publication  
First Author: Russo AM
Year: 2019
Journal: Behav Brain Res
Title: Social approach, anxiety, and altered tryptophan hydroxylase 2 activity in juvenile BALB/c and C57BL/6J mice.
Volume: 359
Pages: 918-926
Publication  
First Author: Campanelli F
Year: 2021
Journal: Neurobiol Dis
Title: Serotonin drives striatal synaptic plasticity in a sex-related manner.
Volume: 158
Pages: 105448
Publication
First Author: Muzerelle A
Year: 2021
Journal: Sci Rep
Title: Dorsal raphe serotonin neurotransmission is required for the expression of nursing behavior and for pup survival.
Volume: 11
Issue: 1
Pages: 6004
Publication
First Author: Côté F
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function.
Volume: 100
Issue: 23
Pages: 13525-30
Publication
First Author: Savelieva KV
Year: 2008
Journal: PLoS One
Title: Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants.
Volume: 3
Issue: 10
Pages: e3301
Publication
First Author: Sakowski SA
Year: 2006
Journal: Brain Res
Title: Differential tissue distribution of tryptophan hydroxylase isoforms 1 and 2 as revealed with monospecific antibodies.
Volume: 1085
Issue: 1
Pages: 11-8
Publication
First Author: Liu Y
Year: 2023
Journal: Neuron
Title: Molecular and cellular mechanisms of the first social relationship: A conserved role of 5-HT from mice to monkeys, upstream of oxytocin.
Volume: 111
Issue: 9
Pages: 1468-1485.e7
Publication
First Author: Beaulieu JM
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency.
Volume: 105
Issue: 4
Pages: 1333-8
Publication  
First Author: Jia YF
Year: 2014
Journal: Front Behav Neurosci
Title: Abnormal anxiety- and depression-like behaviors in mice lacking both central serotonergic neurons and pancreatic islet cells.
Volume: 8
Pages: 325
Publication      
First Author: Zhu P
Year: 2022
Journal: Neuron
Title: 5-hydroxytryptamine produced by enteric serotonergic neurons initiates colorectal cancer stem cell self-renewal and tumorigenesis.
Publication
First Author: Li Z
Year: 2011
Journal: J Neurosci
Title: Essential roles of enteric neuronal serotonin in gastrointestinal motility and the development/survival of enteric dopaminergic neurons.
Volume: 31
Issue: 24
Pages: 8998-9009
Publication
First Author: Izikki M
Year: 2007
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Tryptophan hydroxylase 1 knockout and tryptophan hydroxylase 2 polymorphism: effects on hypoxic pulmonary hypertension in mice.
Volume: 293
Issue: 4
Pages: L1045-52
Publication
First Author: Huo Y
Year: 2018
Journal: PLoS One
Title: Tph2-/- female mice restore socio-sexual recognition through upregulating ERα and OTR genes in the amygdala.
Volume: 13
Issue: 2
Pages: e0193395
Publication
First Author: Basu B
Year: 2008
Journal: Reproduction
Title: Serotonin in pre-implantation mouse embryos is localized to the mitochondria and can modulate mitochondrial potential.
Volume: 135
Issue: 5
Pages: 657-69
Publication
First Author: Kitt MM
Year: 2022
Journal: Cell Rep
Title: An adult-stage transcriptional program for survival of serotonergic connectivity.
Volume: 39
Issue: 3
Pages: 110711
Publication    
First Author: Donovan LJ
Year: 2019
Journal: Elife
Title: Lmx1b is required at multiple stages to build expansive serotonergic axon architectures.
Volume: 8
Publication
First Author: Wu Q
Year: 2012
Journal: Nature
Title: Deciphering a neuronal circuit that mediates appetite.
Volume: 483
Issue: 7391
Pages: 594-7
Publication  
First Author: Teng T
Year: 2017
Journal: eNeuro
Title: EphrinA5 Signaling Is Required for the Distinctive Targeting of Raphe Serotonin Neurons in the Forebrain.
Volume: 4
Issue: 1
Publication
First Author: Cai X
Year: 2022
Journal: Nat Neurosci
Title: A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice.
Volume: 25
Issue: 5
Pages: 646-658
Publication  
First Author: Kouwenhoven WM
Year: 2021
Journal: Int J Mol Sci
Title: Nkx2.9 Contributes to Mid-Hindbrain Patterning by Regulation of mdDA Neuronal Cell-Fate and Repression of a Hindbrain-Specific Cell-Fate.
Volume: 22
Issue: 23
Publication
First Author: Jacob J
Year: 2009
Journal: Development
Title: Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain.
Volume: 136
Issue: 14
Pages: 2477-85
Publication  
First Author: Pratelli M
Year: 2017
Journal: eNeuro
Title: Perturbation of Serotonin Homeostasis during Adulthood Affects Serotonergic Neuronal Circuitry.
Volume: 4
Issue: 2
Publication
First Author: Migliarini S
Year: 2013
Journal: Mol Psychiatry
Title: Lack of brain serotonin affects postnatal development and serotonergic neuronal circuitry formation.
Volume: 18
Issue: 10
Pages: 1106-18
Publication
First Author: Osipova DV
Year: 2010
Journal: Genes Brain Behav
Title: Distribution of the C1473G polymorphism in tryptophan hydroxylase 2 gene in laboratory and wild mice.
Volume: 9
Issue: 5
Pages: 537-43
Publication
First Author: Isles AR
Year: 2005
Journal: Eur J Neurosci
Title: An mTph2 SNP gives rise to alterations in extracellular 5-HT levels, but not in performance on a delayed-reinforcement task.
Volume: 22
Issue: 4
Pages: 997-1000
Publication  
First Author: Flood ZC
Year: 2012
Journal: Neuroscience
Title: Brain growth trajectories in mouse strains with central and peripheral serotonin differences: relevance to autism models.
Volume: 210
Pages: 286-95
Publication
First Author: Browne CA
Year: 2011
Journal: Neuropharmacology
Title: Differential stress-induced alterations in tryptophan hydroxylase activity and serotonin turnover in two inbred mouse strains.
Volume: 60
Issue: 4
Pages: 683-91
Publication  
First Author: Huq SN
Year: 2021
Journal: Front Neurosci
Title: The Effects of Brain Serotonin Deficiency on Responses to High Fat Diet in Female Mice.
Volume: 15
Pages: 683103
Publication
First Author: Dzirasa K
Year: 2013
Journal: J Neurosci
Title: Cortical-amygdalar circuit dysfunction in a genetic mouse model of serotonin deficiency.
Volume: 33
Issue: 10
Pages: 4505-13
Publication
First Author: Sachs BD
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Brain 5-HT deficiency increases stress vulnerability and impairs antidepressant responses following psychosocial stress.
Volume: 112
Issue: 8
Pages: 2557-62
Publication
First Author: Ren J
Year: 2018
Journal: Cell
Title: Anatomically Defined and Functionally Distinct Dorsal Raphe Serotonin Sub-systems.
Volume: 175
Issue: 2
Pages: 472-487.e20
Publication  
First Author: Song NN
Year: 2016
Journal: Sci Rep
Title: Reducing central serotonin in adulthood promotes hippocampal neurogenesis.
Volume: 6
Pages: 20338
Publication
First Author: Alenina N
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Growth retardation and altered autonomic control in mice lacking brain serotonin.
Volume: 106
Issue: 25
Pages: 10332-7
Publication
First Author: Klempin F
Year: 2013
Journal: J Neurosci
Title: Serotonin is required for exercise-induced adult hippocampal neurogenesis.
Volume: 33
Issue: 19
Pages: 8270-5
Publication  
First Author: van Lingen M
Year: 2019
Journal: Front Cell Dev Biol
Title: Lack of Brain Serotonin Affects Feeding and Differentiation of Newborn Cells in the Adult Hypothalamus.
Volume: 7
Pages: 65
Publication  
First Author: Mosienko V
Year: 2012
Journal: Transl Psychiatry
Title: Exaggerated aggression and decreased anxiety in mice deficient in brain serotonin.
Volume: 2
Pages: e122
Publication
First Author: Montalbano A
Year: 2019
Journal: PLoS One
Title: Dual inhibitory action of trazodone on dorsal raphe serotonergic neurons through 5-HT1A receptor partial agonism and α1-adrenoceptor antagonism.
Volume: 14
Issue: 9
Pages: e0222855
Publication  
First Author: Svirin E
Year: 2022
Journal: Cells
Title: Predation Stress Causes Excessive Aggression in Female Mice with Partial Genetic Inactivation of Tryptophan Hydroxylase-2: Evidence for Altered Myelination-Related Processes.
Volume: 11
Issue: 6
Publication  
First Author: Cai YQ
Year: 2014
Journal: Mol Pain
Title: Optogenetic activation of brainstem serotonergic neurons induces persistent pain sensitization.
Volume: 10
Pages: 70
Publication
First Author: Whitney MS
Year: 2016
Journal: J Neurosci
Title: Adult Brain Serotonin Deficiency Causes Hyperactivity, Circadian Disruption, and Elimination of Siestas.
Volume: 36
Issue: 38
Pages: 9828-42
Publication  
First Author: Huo Y
Year: 2014
Journal: Front Behav Neurosci
Title: Chronic exposure to a predator or its scent does not inhibit male-male competition in male mice lacking brain serotonin.
Volume: 8
Pages: 116
Publication
First Author: Thomas DM
Year: 2010
Journal: J Neurochem
Title: The role of endogenous serotonin in methamphetamine-induced neurotoxicity to dopamine nerve endings of the striatum.
Volume: 115
Issue: 3
Pages: 595-605
Publication
First Author: Angoa-Pérez M
Year: 2015
Journal: PLoS One
Title: Brain serotonin signaling does not determine sexual preference in male mice.
Volume: 10
Issue: 2
Pages: e0118603
Publication  
First Author: Angoa-Pérez M
Year: 2021
Journal: Brain Res
Title: Responses to chronic corticosterone on brain glucocorticoid receptors, adrenal gland, and gut microbiota in mice lacking neuronal serotonin.
Volume: 1751
Pages: 147190
Publication
First Author: Solarewicz JZ
Year: 2015
Journal: Am J Physiol Regul Integr Comp Physiol
Title: The sleep-wake cycle and motor activity, but not temperature, are disrupted over the light-dark cycle in mice genetically depleted of serotonin.
Volume: 308
Issue: 1
Pages: R10-7
Publication
First Author: Angoa-Pérez M
Year: 2014
Journal: Genes Brain Behav
Title: Brain serotonin determines maternal behavior and offspring survival.
Volume: 13
Issue: 7
Pages: 579-91
Publication
First Author: Kane MJ
Year: 2012
Journal: PLoS One
Title: Mice genetically depleted of brain serotonin display social impairments, communication deficits and repetitive behaviors: possible relevance to autism.
Volume: 7
Issue: 11
Pages: e48975
Publication  
First Author: Carlson KS
Year: 2016
Journal: eNeuro
Title: Preservation of Essential Odor-Guided Behaviors and Odor-Based Reversal Learning after Targeting Adult Brain Serotonin Synthesis.
Volume: 3
Issue: 5
Publication
First Author: Walther DJ
Year: 2003
Journal: Science
Title: Synthesis of serotonin by a second tryptophan hydroxylase isoform.
Volume: 299
Issue: 5603
Pages: 76
Publication
First Author: Zhang S
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Serotonin signaling in the brain of adult female mice is required for sexual preference.
Volume: 110
Issue: 24
Pages: 9968-73
Publication
First Author: Walther DJ
Year: 2003
Journal: Biochem Pharmacol
Title: A unique central tryptophan hydroxylase isoform.
Volume: 66
Issue: 9
Pages: 1673-80
Publication
First Author: Côté F
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Maternal serotonin is crucial for murine embryonic development.
Volume: 104
Issue: 1
Pages: 329-34
Publication
First Author: Liu Z
Year: 2014
Journal: Neuron
Title: Dorsal raphe neurons signal reward through 5-HT and glutamate.
Volume: 81
Issue: 6
Pages: 1360-1374
Publication  
First Author: Forero A
Year: 2020
Journal: Neuropharmacology
Title: Serotonin (5-HT) neuron-specific inactivation of Cadherin-13 impacts 5-HT system formation and cognitive function.
Volume: 168
Pages: 108018
Publication
First Author: Mordhorst A
Year: 2021
Journal: FASEB J
Title: Phenylalanine hydroxylase contributes to serotonin synthesis in mice.
Volume: 35
Issue: 6
Pages: e21648
Publication
First Author: Xi TF
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Central 5-hydroxytryptamine (5-HT) mediates colonic motility by hypothalamus oxytocin-colonic oxytocin receptor pathway.
Volume: 508
Issue: 3
Pages: 959-964
Publication
First Author: Baan M
Year: 2015
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Transgenic expression of the human growth hormone minigene promotes pancreatic β-cell proliferation.
Volume: 309
Issue: 7
Pages: R788-94
Publication  
First Author: Gallardo CM
Year: 2020
Journal: Front Mol Neurosci
Title: Food Anticipatory Activity on Circadian Time Scales Is Not Dependent on Central Serotonin: Evidence From Tryptophan Hydroxylase-2 and Serotonin Transporter Knockout Mice.
Volume: 13
Pages: 534238
Publication
First Author: Ortuño MJ
Year: 2016
Journal: Nat Med
Title: Serotonin-reuptake inhibitors act centrally to cause bone loss in mice by counteracting a local anti-resorptive effect.
Volume: 22
Issue: 10
Pages: 1170-1179
Publication  
First Author: Ortuño MJ
Year: 2021
Journal: J Clin Invest
Title: Melanocortin 4 receptor stimulation prevents antidepressant-associated weight gain in mice caused by long-term fluoxetine exposure.
Volume: 131
Issue: 24
Publication
First Author: Narboux-Nême N
Year: 2013
Journal: ACS Chem Neurosci
Title: Postnatal growth defects in mice with constitutive depletion of central serotonin.
Volume: 4
Issue: 1
Pages: 171-81
Publication
First Author: Kirby PJ
Year: 2002
Journal: Cytogenet Genome Res
Title: Cloning and mapping of platypus SOX2 and SOX14: insights into SOX group B evolution.
Volume: 98
Issue: 1
Pages: 96-100