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Search results 1 to 98 out of 98 for Whrn

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Category: Publication
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Type Details Score
Publication
37066759 | J:345851
First Author: Guan Y
Year: 2023
Journal: Adv Sci (Weinh)
Title: Deafness-Associated ADGRV1 Mutation Impairs USH2A Stability through Improper Phosphorylation of WHRN and WDSUB1 Recruitment.
Volume: 10
Issue: 16
Pages: e2205993
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Publication
28031293 | J:241430
First Author: Zou J
Year: 2017
Journal: Hum Mol Genet
Title: The roles of USH1 proteins and PDZ domain-containing USH proteins in USH2 complex integrity in cochlear hair cells.
Volume: 26
Issue: 3
Pages: 624-636
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Publication
26401052 | J:226845
First Author: Zou J
Year: 2015
Journal: Hum Mol Genet
Title: Individual USH2 proteins make distinct contributions to the ankle link complex during development of the mouse cochlear stereociliary bundle.
Volume: 24
Issue: 24
Pages: 6944-57
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Publication
24334608 | J:209073
First Author: Zou J
Year: 2014
Journal: Hum Mol Genet
Title: Deletion of PDZD7 disrupts the Usher syndrome type 2 protein complex in cochlear hair cells and causes hearing loss in mice.
Volume: 23
Issue: 9
Pages: 2374-90
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Publication
27117407 | J:235390
First Author: Ebrahim S
Year: 2016
Journal: Cell Rep
Title: Alternative Splice Forms Influence Functions of Whirlin in Mechanosensory Hair Cell Stereocilia.
Volume: 15
Issue: 5
Pages: 935-943
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Publication
30447021 | J:283100
First Author: Saifetiarova J
Year: 2019
Journal: J Neurosci Res
Title: Ablation of cytoskeletal scaffolding proteins, Band 4.1B and Whirlin, leads to cerebellar purkinje axon pathology and motor dysfunction.
Volume: 97
Issue: 3
Pages: 313-331
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Publication
24011083 | J:202030
 
First Author: Green JA
Year: 2013
Journal: BMC Neurosci
Title: Whirlin, a cytoskeletal scaffolding protein, stabilizes the paranodal region and axonal cytoskeleton in myelinated axons.
Volume: 14
Pages: 96
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Publication
25406310 | J:218667
First Author: Chen Q
Year: 2014
Journal: J Biol Chem
Title: Whirlin and PDZ domain-containing 7 (PDZD7) proteins are both required to form the quaternary protein complex associated with Usher syndrome type 2.
Volume: 289
Issue: 52
Pages: 36070-88
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Publication
30827920 | J:271898
First Author: Tadenev ALD
Year: 2019
Journal: Curr Biol
Title: GPSM2-GNAI Specifies the Tallest Stereocilia and Defines Hair Bundle Row Identity.
Volume: 29
Issue: 6
Pages: 921-934.e4
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Publication
12124769 | J:77939
First Author: Holme RH
Year: 2002
Journal: J Comp Neurol
Title: Elongation of hair cell stereocilia is defective in the mouse mutant whirler.
Volume: 450
Issue: 1
Pages: 94-102
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Publication
17326148 | J:122600
First Author: Mogensen MM
Year: 2007
Journal: Cell Motil Cytoskeleton
Title: The deaf mouse mutant whirler suggests a role for whirlin in actin filament dynamics and stereocilia development.
Volume: 64
Issue: 7
Pages: 496-508
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Publication
26420843 | J:226841
First Author: Mathur PD
Year: 2015
Journal: Hum Mol Genet
Title: A study of whirlin isoforms in the mouse vestibular system suggests potential vestibular dysfunction in DFNB31-deficient patients.
Volume: 24
Issue: 24
Pages: 7017-30
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Publication
22048959 | J:179695
First Author: Wang L
Year: 2012
Journal: Hum Mol Genet
Title: Whirlin interacts with espin and modulates its actin-regulatory function: an insight into the mechanism of Usher syndrome type II.
Volume: 21
Issue: 3
Pages: 692-710
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Publication
31680869 | J:324365
 
First Author: Kim EJ
Year: 2019
Journal: Front Cell Neurosci
Title: Impact of Auditory Experience on the Structural Plasticity of the AIS in the Mouse Brainstem Throughout the Lifespan.
Volume: 13
Pages: 456
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Publication
26307081 | J:226417
First Author: Mathur PD
Year: 2015
Journal: Hum Mol Genet
Title: Distinct expression and function of whirlin isoforms in the inner ear and retina: an insight into pathogenesis of USH2D and DFNB31.
Volume: 24
Issue: 21
Pages: 6213-28
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Publication
38974964 | J:351467
First Author: Aguilar C
Year: 2024
Journal: iScience
Title: Pleiotropic brain function of whirlin identified by a novel mutation.
Volume: 27
Issue: 7
Pages: 110170
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Publication
10602993 | J:59252
First Author: Paige AJ
Year: 2000
Journal: Mamm Genome
Title: A deletion on chromosome 4 cosegregates with the whirler deafness mutation: exclusion of Orm1 as a candidate.
Volume: 11
Issue: 1
Pages: 51-7
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Publication
- | J:48657
 
First Author: Kiernan BW
Year: 1998
Journal: Hered Deaf News
Title: Abnormalities of the inner ear in a deaf mouse mutant whirler (wi).
Volume: 15
Pages: 36-7
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Publication
5538400 | J:5538
First Author: Weltman AS
Year: 1970
Journal: Physiol Behav
Title: Metabolism rate, biochemical and endocrine alterations in male whirler mice.
Volume: 5
Issue: 1
Pages: 17-22
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Publication
15590699 | J:95916
First Author: Kikkawa Y
Year: 2005
Journal: Hum Mol Genet
Title: Mutant analysis reveals whirlin as a dynamic organizer in the growing hair cell stereocilium.
Volume: 14
Issue: 3
Pages: 391-400
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Publication
6034501 | J:5037
First Author: Sackler AM
Year: 1967
Journal: J Exp Zool
Title: Metabolic and endocrine differences between the mutation whirler and normal female mice.
Volume: 164
Issue: 2
Pages: 133-40
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Publication
15654330 | J:102099
First Author: Belyantseva IA
Year: 2005
Journal: Nat Cell Biol
Title: Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereocilia.
Volume: 7
Issue: 2
Pages: 148-56
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Publication
17584769 | J:143824
First Author: Gosens I
Year: 2007
Journal: Hum Mol Genet
Title: MPP1 links the Usher protein network and the Crumbs protein complex in the retina.
Volume: 16
Issue: 16
Pages: 1993-2003
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Publication
25698744 | J:219861
First Author: de Nooij JC
Year: 2015
Journal: J Neurosci
Title: The PDZ-domain protein Whirlin facilitates mechanosensory signaling in mammalian proprioceptors.
Volume: 35
Issue: 7
Pages: 3073-84
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Publication
8088529 | J:18899
First Author: Rinchik EM
Year: 1994
Journal: Genetics
Title: Molecular genetics of the brown (b)-locus region of mouse chromosome 4. II. Complementation analyses of lethal brown deletions.
Volume: 137
Issue: 3
Pages: 855-65
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11932245 | J:75900
First Author: Cryns K
Year: 2002
Journal: Genome Res
Title: Vestibular dysfunction in the epistatic circler mouse is caused by phenotypic interaction of one recessive gene and three modifier genes.
Volume: 12
Issue: 4
Pages: 613-7
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Publication
14098314 | J:269
 
First Author: LANE PW
Year: 1963
Journal: J Hered
Title: WHIRLER MICE: A RECESSIVE BEHAVIOR MUTATION IN LINKAGE GROUP VIII.
Volume: 54
Pages: 263-6
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26516054 | J:250693
First Author: Ciardo MG
Year: 2016
Journal: Biochim Biophys Acta
Title: Whirlin increases TRPV1 channel expression and cellular stability.
Volume: 1863
Issue: 1
Pages: 115-27
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Publication
24211856 | J:210386
 
First Author: Tian M
Year: 2014
Journal: Exp Eye Res
Title: Photoreceptors in whirler mice show defective transducin translocation and are susceptible to short-term light/dark changes-induced degeneration.
Volume: 118
Pages: 145-53
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7916309 | J:18898
First Author: Rinchik EM
Year: 1994
Journal: Genetics
Title: Molecular genetics of the brown (b)-locus region of mouse chromosome 4. I. Origin and molecular mapping of radiation- and chemical-induced lethal brown deletions.
Volume: 137
Issue: 3
Pages: 845-54
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Publication
16301217 | J:186070
First Author: Adato A
Year: 2005
Journal: Hum Mol Genet
Title: Usherin, the defective protein in Usher syndrome type IIA, is likely to be a component of interstereocilia ankle links in the inner ear sensory cells.
Volume: 14
Issue: 24
Pages: 3921-32
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Publication
21236676 | J:171832
First Author: Manor U
Year: 2011
Journal: Curr Biol
Title: Regulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8.
Volume: 21
Issue: 2
Pages: 167-72
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Publication
15590698 | J:95920
First Author: Delprat B
Year: 2005
Journal: Hum Mol Genet
Title: Myosin XVa and whirlin, two deafness gene products required for hair bundle growth, are located at the stereocilia tips and interact directly.
Volume: 14
Issue: 3
Pages: 401-10
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16829577 | J:111803
First Author: Mburu P
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Whirlin complexes with p55 at the stereocilia tip during hair cell development.
Volume: 103
Issue: 29
Pages: 10973-8
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Publication
22323458 | J:196243
First Author: Wright RN
Year: 2012
Journal: Invest Ophthalmol Vis Sci
Title: RpgrORF15 connects to the usher protein network through direct interactions with multiple whirlin isoforms.
Volume: 53
Issue: 3
Pages: 1519-29
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Publication
12833159 | J:86904
First Author: Mburu P
Year: 2003
Journal: Nat Genet
Title: Defects in whirlin, a PDZ domain molecule involved in stereocilia elongation, cause deafness in the whirler mouse and families with DFNB31.
Volume: 34
Issue: 4
Pages: 421-8
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Publication
16434480 | J:106765
First Author: van Wijk E
Year: 2006
Journal: Hum Mol Genet
Title: The DFNB31 gene product whirlin connects to the Usher protein network in the cochlea and retina by direct association with USH2A and VLGR1.
Volume: 15
Issue: 5
Pages: 751-65
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Publication
- | J:13477
 
First Author: Lane PW
Year: 1968
Journal: Mouse News Lett
Title: New allele of diabetes.
Volume: 38
Pages: 24
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Publication
18160714 | J:132633
First Author: Prosser HM
Year: 2008
Journal: Mol Cell Biol
Title: Mosaic complementation demonstrates a regulatory role for myosin VIIa in actin dynamics of stereocilia.
Volume: 28
Issue: 5
Pages: 1702-12
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Publication
- | J:212307
       
First Author: IMGC
Year: 2014
Title: Abstracts for the IMGC2014 meeting (October, 2014)
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Publication
28387217 | J:250575
 
First Author: Mauriac SA
Year: 2017
Journal: Nat Commun
Title: Defective Gpsm2/Gαi3 signalling disrupts stereocilia development and growth cone actin dynamics in Chudley-McCullough syndrome.
Volume: 8
Pages: 14907
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Publication
- | J:44122
 
First Author: Paige AJW
Year: 1997
Journal: Genet Res
Title: Genetic and physical mapping in the vicinity of the wi locus on mouse Chromosome 4
Volume: 70
Pages: 85 (Abstr.)
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- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
20502675 | J:160677
First Author: Yang J
Year: 2010
Journal: PLoS Genet
Title: Ablation of whirlin long isoform disrupts the USH2 protein complex and causes vision and hearing loss.
Volume: 6
Issue: 5
Pages: e1000955
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Publication
23055499 | J:266117
First Author: Grati M
Year: 2012
Journal: J Neurosci
Title: Localization of PDZD7 to the stereocilia ankle-link associates this scaffolding protein with the Usher syndrome protein network.
Volume: 32
Issue: 41
Pages: 14288-93
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Publication
33009420 | J:299425
First Author: Michel V
Year: 2020
Journal: Sci Rep
Title: Interaction of protocadherin-15 with the scaffold protein whirlin supports its anchoring of hair-bundle lateral links in cochlear hair cells.
Volume: 10
Issue: 1
Pages: 16430
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Publication
19363478 | J:151354
First Author: Lewis MA
Year: 2009
Journal: Nat Genet
Title: An ENU-induced mutation of miR-96 associated with progressive hearing loss in mice.
Volume: 41
Issue: 5
Pages: 614-8
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20332152 | J:158897
First Author: Etournay R
Year: 2010
Journal: Development
Title: Cochlear outer hair cells undergo an apical circumference remodeling constrained by the hair bundle shape.
Volume: 137
Issue: 8
Pages: 1373-83
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- | J:39923
First Author: British Society of Audiology short papers meeting on experimental studies of hearing and deafness. Cambridge, United Kingdom, 22-23 September 1996. Kiernan BW
Year: 1997
Journal: Br J Audiol
Title: Analysis of the deaf mouse mutant, whirler.
Volume: 31
Issue: 2
Pages: 73-132 (84-5 Abstr.)
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17906286 | J:132040
First Author: Maerker T
Year: 2008
Journal: Hum Mol Genet
Title: A novel Usher protein network at the periciliary reloading point between molecular transport machineries in vertebrate photoreceptor cells.
Volume: 17
Issue: 1
Pages: 71-86
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Publication
8088814 | J:18269
First Author: Fleming J
Year: 1994
Journal: Genomics
Title: Linkage analysis of the whirler deafness gene on mouse chromosome 4.
Volume: 21
Issue: 1
Pages: 42-8
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10337627 | J:54496
First Author: Rogers MJ
Year: 1999
Journal: Mamm Genome
Title: Genetic mapping of the whirler mutation.
Volume: 10
Issue: 5
Pages: 513-9
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Publication
21212183 | J:171542
First Author: Zou J
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Whirlin replacement restores the formation of the USH2 protein complex in whirlin knockout photoreceptors.
Volume: 52
Issue: 5
Pages: 2343-51
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
31448880 | J:283627
First Author: Dunbar LA
Year: 2019
Journal: EMBO Mol Med
Title: Clarin-2 is essential for hearing by maintaining stereocilia integrity and function.
Volume: 11
Issue: 9
Pages: e10288
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24239741 | J:218725
 
First Author: Cosgrove D
Year: 2014
Journal: Int J Biochem Cell Biol
Title: Usher protein functions in hair cells and photoreceptors.
Volume: 46
Pages: 80-9
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28663585 | J:244562
First Author: Giese APJ
Year: 2017
Journal: Nat Commun
Title: CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells.
Volume: 8
Issue: 1
Pages: 43
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17567809 | J:122415
First Author: Michalski N
Year: 2007
Journal: J Neurosci
Title: Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.
Volume: 27
Issue: 24
Pages: 6478-88
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Publication
36260679 | J:330604
First Author: Akturk A
Year: 2022
Journal: Sci Adv
Title: RGS12 polarizes the GPSM2-GNAI complex to organize and elongate stereocilia in sensory hair cells.
Volume: 8
Issue: 42
Pages: eabq2826
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20016102 | J:157099
First Author: Grimsley-Myers CM
Year: 2009
Journal: J Neurosci
Title: The small GTPase Rac1 regulates auditory hair cell morphogenesis.
Volume: 29
Issue: 50
Pages: 15859-69
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27534441 | J:234901
 
First Author: Potter PK
Year: 2016
Journal: Nat Commun
Title: Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.
Volume: 7
Pages: 12444
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Publication
- | J:90559
     
First Author: The Mammalian Genetics Unit at Harwell
Year: 2004
Journal: Unpublished
Title: Information obtained from the Mammalian Genetics Unit, Medical Research Council (MRC), Harwell, UK
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19554387 | J:156036
First Author: Schilling K
Year: 2009
Journal: Cerebellum
Title: The treasury of the commons: making use of public gene expression resources to better characterize the molecular diversity of inhibitory interneurons in the cerebellar cortex.
Volume: 8
Issue: 4
Pages: 477-89
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Publication
12693553 | J:83413
First Author: Okazaki N
Year: 2003
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 10
Issue: 1
Pages: 35-48
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26238476 | J:226028
First Author: Lewandowski JP
Year: 2015
Journal: Dev Biol
Title: Spatiotemporal regulation of GLI target genes in the mammalian limb bud.
Volume: 406
Issue: 1
Pages: 92-103
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32290105 | J:282558
 
First Author: Collin GB
Year: 2020
Journal: Cells
Title: Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.
Volume: 9
Issue: 4
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Publication
- | J:175295
     
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
19959638 | J:164341
First Author: Kersten FF
Year: 2010
Journal: Invest Ophthalmol Vis Sci
Title: Association of whirlin with Cav1.3 (alpha1D) channels in photoreceptors, defining a novel member of the usher protein network.
Volume: 51
Issue: 5
Pages: 2338-46
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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