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Search results 1 to 100 out of 133 for Xrcc6

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Category: Publication
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Type Details Score
Publication
8661113 | J:33936
First Author: Takiguchi Y
Year: 1996
Journal: Genomics
Title: Genomic structure and chromosomal assignment of the mouse Ku70 gene.
Volume: 35
Issue: 1
Pages: 129-35
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Publication
9223317 | J:41941
First Author: Gu Y
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination.
Volume: 94
Issue: 15
Pages: 8076-81
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Publication
9625768 | J:110884
First Author: Manis JP
Year: 1998
Journal: J Exp Med
Title: Ku70 is required for late B cell development and immunoglobulin heavy chain class switching.
Volume: 187
Issue: 12
Pages: 2081-9
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Publication
18506893 | J:138646
First Author: Teoh NC
Year: 2008
Journal: Hepatology
Title: Defective DNA strand break repair causes chromosomal instability and accelerates liver carcinogenesis in mice.
Volume: 47
Issue: 6
Pages: 2078-88
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Publication
21398614 | J:172454
First Author: Zhang X
Year: 2011
Journal: J Immunol
Title: Cutting edge: Ku70 is a novel cytosolic DNA sensor that induces type III rather than type I IFN.
Volume: 186
Issue: 8
Pages: 4541-5
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Publication
9702186 | J:48929
First Author: Li GC
Year: 1998
Journal: Mol Cell
Title: Ku70: a candidate tumor suppressor gene for murine T cell lymphoma.
Volume: 2
Issue: 1
Pages: 1-8
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Publication
37653239 | J:340115
First Author: Myler LR
Year: 2023
Journal: Nat Struct Mol Biol
Title: DNA-PK and the TRF2 iDDR inhibit MRN-initiated resection at leading-end telomeres.
Volume: 30
Issue: 9
Pages: 1346-1356
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Publication
34428289 | J:310821
First Author: Saha J
Year: 2021
Journal: Nucleic Acids Res
Title: Ablating putative Ku70 phosphorylation sites results in defective DNA damage repair and spontaneous induction of hepatocellular carcinoma.
Volume: 49
Issue: 17
Pages: 9836-9850
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Publication
7565861 | J:28779
First Author: Thompson LH
Year: 1995
Journal: Mutat Res
Title: Nomenclature of human genes involved in ionizing radiation sensitivity.
Volume: 337
Issue: 2
Pages: 131-4
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Publication
8597595 | J:31754
First Author: Paesen GC
Year: 1996
Journal: Biochim Biophys Acta
Title: A tick homologue of the human DNA helicase II 70-kDa subunit.
Volume: 1305
Issue: 3
Pages: 120-4
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Publication
18584027 | J:161655
First Author: Bennardo N
Year: 2008
Journal: PLoS Genet
Title: Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair.
Volume: 4
Issue: 6
Pages: e1000110
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Publication
21349273 | J:170708
First Author: Yano K
Year: 2011
Journal: FEBS Lett
Title: Functional significance of the interaction with Ku in DNA double-strand break recognition of XLF.
Volume: 585
Issue: 6
Pages: 841-6
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Publication
22037767 | J:183676
First Author: Fell VL
Year: 2012
Journal: Mol Cell Biol
Title: Ku regulates signaling to DNA damage response pathways through the Ku70 von Willebrand A domain.
Volume: 32
Issue: 1
Pages: 76-87
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Publication
12551933 | J:82574
First Author: Leskov KS
Year: 2003
Journal: J Biol Chem
Title: Synthesis and functional analyses of nuclear clusterin, a cell death protein.
Volume: 278
Issue: 13
Pages: 11590-600
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Publication
1701785 | J:15671
First Author: Porges AJ
Year: 1990
Journal: J Immunol
Title: Antigenic determinants of the Ku (p70/p80) autoantigen are poorly conserved between species.
Volume: 145
Issue: 12
Pages: 4222-8
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Publication
1641347 | J:1686
First Author: Falzon M
Year: 1992
Journal: Nucleic Acids Res
Title: The nucleotide sequence of a mouse cDNA encoding the 80 kDa subunit of the Ku (p70/p80) autoantigen.
Volume: 20
Issue: 14
Pages: 3784
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Publication
25811803 | J:316581
 
First Author: Ngo J
Year: 2015
Journal: Cell Death Dis
Title: Bax deficiency extends the survival of Ku70 knockout mice that develop lung and heart diseases.
Volume: 6
Pages: e1706
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Publication
9294146 | J:108657
First Author: Ouyang H
Year: 1997
Journal: J Exp Med
Title: Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination In vivo.
Volume: 186
Issue: 6
Pages: 921-9
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Publication
10576891 | J:57758
First Author: Hurd YL
Year: 1999
Journal: Mol Cell Neurosci
Title: A novel neuron-specific DNA end-binding factor in the murine brain.
Volume: 14
Issue: 3
Pages: 213-24
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Publication
16845382 | J:115641
First Author: Celli GB
Year: 2006
Journal: Nat Cell Biol
Title: Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination.
Volume: 8
Issue: 8
Pages: 885-90
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Publication
18849970 | J:143599
First Author: Bredemeyer AL
Year: 2008
Journal: Nature
Title: DNA double-strand breaks activate a multi-functional genetic program in developing lymphocytes.
Volume: 456
Issue: 7223
Pages: 819-23
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Publication
17875923 | J:129043
First Author: Li H
Year: 2007
Journal: Mol Cell Biol
Title: Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer.
Volume: 27
Issue: 23
Pages: 8205-14
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Publication
23857907 | J:333244
First Author: Ahmed EA
Year: 2013
Journal: J Cell Sci
Title: Ku70 and non-homologous end joining protect testicular cells from DNA damage.
Volume: 126
Issue: Pt 14
Pages: 3095-104
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Publication
35545041 | J:326401
First Author: Wang Y
Year: 2022
Journal: Cell Rep
Title: SETD4-mediated KU70 methylation suppresses apoptosis.
Volume: 39
Issue: 6
Pages: 110794
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Publication
9362500 | J:320136
First Author: Jin S
Year: 1997
Journal: EMBO J
Title: Double-strand break repair by Ku70 requires heterodimerization with Ku80 and DNA binding functions.
Volume: 16
Issue: 22
Pages: 6874-85
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Publication
10441505 | J:56768
First Author: Osipovich O
Year: 1999
Journal: Biochem Biophys Res Commun
Title: Defining functional domains of Ku80: DNA end binding and survival after radiation.
Volume: 261
Issue: 3
Pages: 802-7
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Publication
16354685 | J:104162
First Author: Weinstock DM
Year: 2006
Journal: Mol Cell Biol
Title: Alternative pathways for the repair of RAG-induced DNA breaks.
Volume: 26
Issue: 1
Pages: 131-9
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Publication
17272272 | J:121153
First Author: Tomimatsu N
Year: 2007
Journal: J Biol Chem
Title: Ku70/80 modulates ATM and ATR signaling pathways in response to DNA double strand breaks.
Volume: 282
Issue: 14
Pages: 10138-45
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Publication
17325036 | J:121403
First Author: Mazumder S
Year: 2007
Journal: Mol Cell Biol
Title: Interaction of a cyclin E fragment with Ku70 regulates Bax-mediated apoptosis.
Volume: 27
Issue: 9
Pages: 3511-20
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Publication
18710944 | J:140966
First Author: Sundaresan NR
Year: 2008
Journal: Mol Cell Biol
Title: SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70.
Volume: 28
Issue: 20
Pages: 6384-401
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Publication
23610439 | J:197342
First Author: Truong LN
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells.
Volume: 110
Issue: 19
Pages: 7720-5
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Publication
9582343 | J:47726
First Author: Fukumura R
Year: 1998
Journal: J Biol Chem
Title: Murine cell line SX9 bearing a mutation in the dna-pkcs gene exhibits aberrant V(D)J recombination not only in the coding joint but also in the signal joint.
Volume: 273
Issue: 21
Pages: 13058-64
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Publication
32103174 | J:287062
First Author: Shao Z
Year: 2020
Journal: Nature
Title: DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis.
Volume: 579
Issue: 7798
Pages: 291-296
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Publication
38277448 | J:344560
First Author: Pandey A
Year: 2024
Journal: Sci Adv
Title: Ku70 senses cytosolic DNA and assembles a tumor-suppressive signalosome.
Volume: 10
Issue: 4
Pages: eadh3409
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Publication
20383123 | J:159280
First Author: Roberts SA
Year: 2010
Journal: Nature
Title: Ku is a 5'-dRP/AP lyase that excises nucleotide damage near broken ends.
Volume: 464
Issue: 7292
Pages: 1214-7
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Publication
9390689 | J:44361
First Author: Gu Y
Year: 1997
Journal: Immunity
Title: Growth retardation and leaky SCID phenotype of Ku70-deficient mice.
Volume: 7
Issue: 5
Pages: 653-65
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Publication
23474484 | J:208670
First Author: Tavana O
Year: 2013
Journal: Diabetes
Title: Ku70 functions in addition to nonhomologous end joining in pancreatic β-cells: a connection to β-catenin regulation.
Volume: 62
Issue: 7
Pages: 2429-38
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Publication
24394664 | J:208689
First Author: Qing Y
Year: 2014
Journal: Blood
Title: Bcl2 overexpression rescues the hematopoietic stem cell defects in Ku70-deficient mice by restoration of quiescence.
Volume: 123
Issue: 7
Pages: 1002-11
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Publication
23752193 | J:212586
First Author: Puebla-Osorio N
Year: 2014
Journal: Oncogene
Title: A novel Ku70 function in colorectal homeostasis separate from nonhomologous end joining.
Volume: 33
Issue: 21
Pages: 2748-57
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Publication
9736627 | J:50055
First Author: Takata M
Year: 1998
Journal: EMBO J
Title: Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells.
Volume: 17
Issue: 18
Pages: 5497-508
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Publication
29490055 | J:261945
First Author: Maekawa T
Year: 2018
Journal: Nucleic Acids Res
Title: ATF7 mediates TNF-α-induced telomere shortening.
Volume: 46
Issue: 9
Pages: 4487-4504
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Publication
14668445 | J:87802
First Author: Libby BJ
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Positional cloning and characterization of Mei1, a vertebrate-specific gene required for normal meiotic chromosome synapsis in mice.
Volume: 100
Issue: 26
Pages: 15706-11
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Publication
11516951 | J:115412
First Author: d'Adda di Fagagna F
Year: 2001
Journal: Curr Biol
Title: Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells.
Volume: 11
Issue: 15
Pages: 1192-6
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Publication
20854421 | J:217052
First Author: Akhter S
Year: 2010
Journal: Aging Cell
Title: The telomeric protein SNM1B/Apollo is required for normal cell proliferation and embryonic development.
Volume: 9
Issue: 6
Pages: 1047-56
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Publication
12604618 | J:82010
First Author: Hamer G
Year: 2003
Journal: Biol Reprod
Title: Function of DNA-protein kinase catalytic subunit during the early meiotic prophase without Ku70 and Ku86.
Volume: 68
Issue: 3
Pages: 717-21
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Publication
19664609 | J:157421
 
First Author: Liu J
Year: 2009
Journal: Brain Res
Title: The DNA-PK catalytic subunit regulates Bax-mediated excitotoxic cell death by Ku70 phosphorylation.
Volume: 1296
Pages: 164-75
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Publication
19330025 | J:148795
First Author: Li H
Year: 2009
Journal: Oncogene
Title: Deleting Ku70 is milder than deleting Ku80 in p53-mutant mice and cells.
Volume: 28
Issue: 16
Pages: 1875-8
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Publication
10823907 | J:62721
First Author: Ferguson DO
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations.
Volume: 97
Issue: 12
Pages: 6630-3
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Publication
9823897 | J:50865
First Author: Frank KM
Year: 1998
Journal: Nature
Title: Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV.
Volume: 396
Issue: 6707
Pages: 173-7
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Publication
9990036 | J:53765
First Author: Kurimasa A
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Catalytic subunit of DNA-dependent protein kinase: impact on lymphocyte development and tumorigenesis.
Volume: 96
Issue: 4
Pages: 1403-8
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Publication
12119352 | J:120697
First Author: Ishii KJ
Year: 2002
Journal: J Exp Med
Title: Potential role of phosphatidylinositol 3 kinase, rather than DNA-dependent protein kinase, in CpG DNA-induced immune activation.
Volume: 196
Issue: 2
Pages: 269-74
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Publication
24466051 | J:212564
First Author: Choi YJ
Year: 2014
Journal: PLoS One
Title: Deletion of individual Ku subunits in mice causes an NHEJ-independent phenotype potentially by altering apurinic/apyrimidinic site repair.
Volume: 9
Issue: 1
Pages: e86358
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Publication
19692349 | J:154003
First Author: Vishnudas VK
Year: 2009
Journal: Hum Mol Genet
Title: Ku70 regulates Bax-mediated pathogenesis in laminin-alpha2-deficient human muscle cells and mouse models of congenital muscular dystrophy.
Volume: 18
Issue: 23
Pages: 4467-77
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Publication
15870260 | J:98880
First Author: Katz DJ
Year: 2005
Journal: Mol Cell Biol
Title: Functional characterization of a novel Ku70/80 pause site at the H19/Igf2 imprinting control region.
Volume: 25
Issue: 10
Pages: 3855-63
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Publication
10207111 | J:320262
First Author: Kurimasa A
Year: 1999
Journal: Mol Cell Biol
Title: Requirement for the kinase activity of human DNA-dependent protein kinase catalytic subunit in DNA strand break rejoining.
Volume: 19
Issue: 5
Pages: 3877-84
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Publication
19247369 | J:164188
First Author: Gama V
Year: 2009
Journal: Cell Death Differ
Title: Hdm2 is a ubiquitin ligase of Ku70-Akt promotes cell survival by inhibiting Hdm2-dependent Ku70 destabilization.
Volume: 16
Issue: 5
Pages: 758-69
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Publication
20966962 | J:186325
First Author: De Zio D
Year: 2011
Journal: Cell Death Differ
Title: The DNA repair complex Ku70/86 modulates Apaf1 expression upon DNA damage.
Volume: 18
Issue: 3
Pages: 516-27
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Publication
20339076 | J:158884
First Author: Sfeir A
Year: 2010
Journal: Science
Title: Loss of Rap1 induces telomere recombination in the absence of NHEJ or a DNA damage signal.
Volume: 327
Issue: 5973
Pages: 1657-61
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Publication
26941064 | J:236339
 
First Author: Rai R
Year: 2016
Journal: Nat Commun
Title: TRF2-RAP1 is required to protect telomeres from engaging in homologous recombination-mediated deletions and fusions.
Volume: 7
Pages: 10881
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Publication
20142431 | J:158825
First Author: Boboila C
Year: 2010
Journal: J Exp Med
Title: Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4.
Volume: 207
Issue: 2
Pages: 417-27
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Publication
20133803 | J:157537
First Author: Boboila C
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70.
Volume: 107
Issue: 7
Pages: 3034-9
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Publication
15678105 | J:96474
First Author: Dragoi AM
Year: 2005
Journal: EMBO J
Title: DNA-PKcs, but not TLR9, is required for activation of Akt by CpG-DNA.
Volume: 24
Issue: 4
Pages: 779-89
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Publication
20150414 | J:173439
First Author: Wang H
Year: 2010
Journal: Nucleic Acids Res
Title: Characteristics of DNA-binding proteins determine the biological sensitivity to high-linear energy transfer radiation.
Volume: 38
Issue: 10
Pages: 3245-51
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Publication
17318223 | J:139260
First Author: Wang X
Year: 2007
Journal: Cell Death Differ
Title: Haploinsufficiency of Parp1 accelerates Brca1-associated centrosome amplification, telomere shortening, genetic instability, apoptosis, and embryonic lethality.
Volume: 14
Issue: 5
Pages: 924-31
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Publication
28057860 | J:240170
First Author: Bhargava R
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Contribution of canonical nonhomologous end joining to chromosomal rearrangements is enhanced by ATM kinase deficiency.
Volume: 114
Issue: 4
Pages: 728-733
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Publication
11751629 | J:73443
First Author: Pierce AJ
Year: 2001
Journal: Genes Dev
Title: Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells.
Volume: 15
Issue: 24
Pages: 3237-42
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Publication
15485900 | J:94149
First Author: Stark JM
Year: 2004
Journal: Mol Cell Biol
Title: Genetic steps of mammalian homologous repair with distinct mutagenic consequences.
Volume: 24
Issue: 21
Pages: 9305-16
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Publication
8954777 | J:36983
First Author: Koike M
Year: 1996
Journal: Genomics
Title: Chromosomal localization of the mouse and rat DNA double-strand break repair genes Ku p70 and Ku p80/XRCC5 and their mRNA expression in various mouse tissues.
Volume: 38
Issue: 1
Pages: 38-44
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Publication
18625717 | J:140239
First Author: Wu P
Year: 2008
Journal: Mol Cell Biol
Title: No overt nucleosome eviction at deprotected telomeres.
Volume: 28
Issue: 18
Pages: 5724-35
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Publication
14988733 | J:88876
First Author: Dreveny I
Year: 2004
Journal: EMBO J
Title: Structural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47.
Volume: 23
Issue: 5
Pages: 1030-9
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Publication
28759779 | J:277029
 
First Author: Xing M
Year: 2017
Journal: DNA Repair (Amst)
Title: Synthetic lethality between murine DNA repair factors XLF and DNA-PKcs is rescued by inactivation of Ku70.
Volume: 57
Pages: 133-138
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Publication
11248063 | J:68074
First Author: Sekiguchi J
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Genetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and development.
Volume: 98
Issue: 6
Pages: 3243-8
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Publication
19057578 | J:157375
First Author: Gurley KE
Year: 2009
Journal: EMBO Rep
Title: DNA-PK suppresses a p53-independent apoptotic response to DNA damage.
Volume: 10
Issue: 1
Pages: 87-93
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Publication
19221393 | J:146799
First Author: Helmink BA
Year: 2009
Journal: J Exp Med
Title: MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks.
Volume: 206
Issue: 3
Pages: 669-79
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Publication
29323295 | J:253597
First Author: Garaycoechea JI
Year: 2018
Journal: Nature
Title: Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells.
Volume: 553
Issue: 7687
Pages: 171-177
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Publication
12186839 | J:78496
First Author: Difilippantonio MJ
Year: 2002
Journal: J Exp Med
Title: Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification.
Volume: 196
Issue: 4
Pages: 469-80
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Publication
12846809 | J:85021
 
First Author: Mills KD
Year: 2003
Journal: Immunol Rev
Title: The role of DNA breaks in genomic instability and tumorigenesis.
Volume: 194
Pages: 77-95
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Publication
10716994 | J:110848
First Author: Gu Y
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice.
Volume: 97
Issue: 6
Pages: 2668-73
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Publication
15979950 | J:105008
First Author: Griffin C
Year: 2005
Journal: DNA Repair (Amst)
Title: The involvement of key DNA repair pathways in the formation of chromosome rearrangements in embryonic stem cells.
Volume: 4
Issue: 9
Pages: 1019-27
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Publication
22445484 | J:183455
First Author: Bunting SF
Year: 2012
Journal: Mol Cell
Title: BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair.
Volume: 46
Issue: 2
Pages: 125-35
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Publication
23345432 | J:194333
First Author: Oksenych V
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Functional redundancy between the XLF and DNA-PKcs DNA repair factors in V(D)J recombination and nonhomologous DNA end joining.
Volume: 110
Issue: 6
Pages: 2234-9
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Publication
21568942 | J:172439
First Author: Lur G
Year: 2011
Journal: Biochem J
Title: InsP₃receptors and Orai channels in pancreatic acinar cells: co-localization and its consequences.
Volume: 436
Issue: 2
Pages: 231-9
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Publication
2072923 | J:11336
First Author: Baughman G
Year: 1991
Journal: Mol Endocrinol
Title: Genes newly identified as regulated by glucocorticoids in murine thymocytes.
Volume: 5
Issue: 5
Pages: 637-44
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Publication
14576192 | J:88676
First Author: Hammer F
Year: 2004
Journal: Endocrinology
Title: Transcriptional regulation of P450scc gene expression in the embryonic rodent nervous system.
Volume: 145
Issue: 2
Pages: 901-12
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Publication
30017584 | J:265834
First Author: Hung PJ
Year: 2018
Journal: Mol Cell
Title: MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining.
Volume: 71
Issue: 2
Pages: 332-342.e8
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Publication
25818648 | J:220823
First Author: Jiang W
Year: 2015
Journal: Mol Cell
Title: Differential phosphorylation of DNA-PKcs regulates the interplay between end-processing and end-ligation during nonhomologous end-joining.
Volume: 58
Issue: 1
Pages: 172-85
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